Mutagenetix > Incidental Mutation

Incidental Mutation 'R4962:Tenm3'

381841

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Ten-m3, Odz3, 2610100B16Rik

MMRRC Submission

042559-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.598) question?

Stock #

R4962 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

48227682-48843951 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 48278961 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Stop codon at position 1287 (K1287*)

Ref Sequence

ENSEMBL: ENSMUSP00000140141 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000033965
AA Change: K1303*

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: K1303*

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000129821
AA Change: K941*

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000145344

Predicted Effect

probably null
Transcript: ENSMUST00000190840
AA Change: K1287*

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: K1287*

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.7%
20x: 93.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921509C19Rik	A	G	2: 151,472,808 (GRCm38)	F317L	possibly damaging	Het
Abcc4	A	G	14: 118,668,399 (GRCm38)	I85T	probably benign	Het
Acoxl	G	T	2: 128,075,890 (GRCm38)	C498F	probably damaging	Het
Akap13	C	T	7: 75,749,430 (GRCm38)	T2752I	probably damaging	Het
Anks6	C	T	4: 47,030,795 (GRCm38)	G601S	probably damaging	Het
Ap2a2	T	G	7: 141,630,148 (GRCm38)	F836C	probably damaging	Het
Atp2c1	A	G	9: 105,442,950 (GRCm38)	V404A	probably benign	Het
Atp7b	G	T	8: 22,020,885 (GRCm38)	A415E	probably damaging	Het
Babam2	A	T	5: 31,785,583 (GRCm38)	I71L	possibly damaging	Het
Bean1	A	G	8: 104,216,974 (GRCm38)	T54A	probably damaging	Het
Cacna1b	T	A	2: 24,618,318 (GRCm38)	I1816F	probably damaging	Het
Cacna1b	C	T	2: 24,657,366 (GRCm38)	G1202D	probably damaging	Het
Casp8ap2	A	G	4: 32,640,554 (GRCm38)	E536G	probably damaging	Het
Cfap57	A	G	4: 118,613,065 (GRCm38)	V206A	probably benign	Het
Clca2	A	T	3: 145,077,879 (GRCm38)	D658E	probably damaging	Het
Cwc22	A	T	2: 77,896,309 (GRCm38)	S809T	probably benign	Het
Cyp2c54	C	T	19: 40,072,141 (GRCm38)	R132Q	possibly damaging	Het
Ddx20	A	T	3: 105,680,605 (GRCm38)	D386E	possibly damaging	Het
Ddx50	T	C	10: 62,642,853 (GRCm38)	T185A	probably damaging	Het
Decr1	G	A	4: 15,930,976 (GRCm38)	R119*	probably null	Het
Dennd4a	T	C	9: 64,906,003 (GRCm38)	S1415P	probably benign	Het
Dnah12	A	T	14: 26,716,700 (GRCm38)	I495L	probably benign	Het
Dnah2	G	A	11: 69,455,973 (GRCm38)	Q2596*	probably null	Het
Dnajb13	A	G	7: 100,507,500 (GRCm38)	L123S	probably benign	Het
Elavl3	G	A	9: 22,036,811 (GRCm38)	P19L	probably benign	Het
Fer1l6	T	C	15: 58,571,401 (GRCm38)	S518P	probably benign	Het
Fgd3	T	C	13: 49,266,629 (GRCm38)	S591G	probably benign	Het
Galnt18	C	A	7: 111,472,064 (GRCm38)	R566L	probably benign	Het
Galnt6	A	T	15: 100,696,574 (GRCm38)	Y525*	probably null	Het
Gm10036	A	T	18: 15,833,302 (GRCm38)	Y170F	probably benign	Het
Hacd2	A	G	16: 35,022,551 (GRCm38)	D24G	unknown	Het
Idh3a	T	C	9: 54,596,041 (GRCm38)	M128T	possibly damaging	Het
Ido1	C	T	8: 24,584,549 (GRCm38)	M359I	probably benign	Het
Ikbkb	T	C	8: 22,681,677 (GRCm38)	T185A	probably damaging	Het
Insl6	C	T	19: 29,321,619 (GRCm38)	G131D	probably damaging	Het
Irgm1	A	C	11: 48,866,332 (GRCm38)	S217R	possibly damaging	Het
Itga11	T	A	9: 62,761,568 (GRCm38)	Y702*	probably null	Het
Itgb4	C	T	11: 115,984,157 (GRCm38)	R447W	probably benign	Het
Kansl2	T	C	15: 98,531,843 (GRCm38)	M103V	probably benign	Het
Kcnq2	T	C	2: 181,112,043 (GRCm38)	N258S	possibly damaging	Het
Kdm5d	A	T	Y: 940,624 (GRCm38)	D1045V	probably damaging	Het
Lats2	A	G	14: 57,699,592 (GRCm38)	L480P	probably damaging	Het
Lin28b	T	A	10: 45,420,640 (GRCm38)	K87N	possibly damaging	Het
Lpgat1	T	A	1: 191,719,570 (GRCm38)	W103R	probably damaging	Het
Lpl	G	T	8: 68,894,693 (GRCm38)	G166C	probably damaging	Het
Ly75	A	T	2: 60,352,125 (GRCm38)	Y569N	probably damaging	Het
Mcm8	A	T	2: 132,838,769 (GRCm38)	E564D	probably damaging	Het
Me2	G	T	18: 73,785,776 (GRCm38)	N411K	probably damaging	Het
Mn1	A	G	5: 111,454,786 (GRCm38)	T1297A	possibly damaging	Het
Mphosph8	T	A	14: 56,678,589 (GRCm38)	F447L	probably benign	Het
Nacad	T	A	11: 6,599,169 (GRCm38)	D1294V	probably damaging	Het
Neu3	A	T	7: 99,823,408 (GRCm38)	F41I	probably damaging	Het
Nlrp6	G	T	7: 140,923,584 (GRCm38)	L534F	probably damaging	Het
Nrap	A	G	19: 56,378,143 (GRCm38)	M338T	probably damaging	Het
Nuak1	T	C	10: 84,375,115 (GRCm38)	K370E	probably damaging	Het
Olfr1151	A	G	2: 87,857,288 (GRCm38)	T38A	probably benign	Het
Olfr1425	T	A	19: 12,074,275 (GRCm38)	D119V	probably damaging	Het
Olfr479	T	A	7: 108,055,440 (GRCm38)	C153S	probably benign	Het
Olfr805	C	T	10: 129,722,723 (GRCm38)	V274M	probably damaging	Het
P3h3	T	C	6: 124,841,773 (GRCm38)	S701G	probably benign	Het
Pdss2	T	C	10: 43,298,912 (GRCm38)	M138T	possibly damaging	Het
Piezo1	C	T	8: 122,486,481 (GRCm38)	E1848K	probably benign	Het
Prmt3	T	G	7: 49,826,809 (GRCm38)	S389A	probably benign	Het
Prrxl1	G	T	14: 32,647,144 (GRCm38)		probably benign	Het
Prune2	T	A	19: 17,122,273 (GRCm38)	F1714I	probably benign	Het
Ptgis	A	G	2: 167,225,274 (GRCm38)		probably null	Het
Ptpn20	T	C	14: 33,614,459 (GRCm38)	V85A	probably benign	Het
Rabepk	A	T	2: 34,780,657 (GRCm38)	Y264N	probably damaging	Het
Ralgapa2	A	T	2: 146,434,834 (GRCm38)	C495*	probably null	Het
Satb2	A	G	1: 56,891,168 (GRCm38)	I232T	probably benign	Het
Selenbp2	A	T	3: 94,703,549 (GRCm38)	L307F	probably damaging	Het
Sgpl1	T	G	10: 61,114,084 (GRCm38)	Y112S	probably damaging	Het
Slitrk5	T	C	14: 111,681,247 (GRCm38)	S768P	probably benign	Het
Smc3	T	A	19: 53,631,517 (GRCm38)	Y615N	probably damaging	Het
Spag17	A	G	3: 100,027,623 (GRCm38)	N715S	probably benign	Het
Spats2	A	G	15: 99,212,276 (GRCm38)	E518G	probably benign	Het
Spats2l	A	G	1: 57,885,824 (GRCm38)	H127R	possibly damaging	Het
Thoc1	T	A	18: 9,962,387 (GRCm38)	S91T	probably benign	Het
Thoc6	C	T	17: 23,669,937 (GRCm38)	G166S	probably damaging	Het
Tmem107	C	A	11: 69,071,261 (GRCm38)	T42N	possibly damaging	Het
Tmprss11c	A	G	5: 86,237,710 (GRCm38)	I288T	probably damaging	Het
Tnrc18	A	G	5: 142,739,493 (GRCm38)	F1827S	unknown	Het
Trmt112	C	A	19: 6,910,198 (GRCm38)	T5N	probably damaging	Het
Trp53bp1	A	T	2: 121,270,546 (GRCm38)	M57K	probably benign	Het
Ttbk2	C	A	2: 120,745,150 (GRCm38)	Q1115H	probably damaging	Het
Ttn	A	G	2: 76,944,109 (GRCm38)	M2151T	probably damaging	Het
Ttn	C	A	2: 76,729,645 (GRCm38)	E27725*	probably null	Het
Usp9y	A	T	Y: 1,384,336 (GRCm38)	D727E	probably damaging	Het
Vps13c	A	G	9: 67,873,891 (GRCm38)	T221A	probably damaging	Het
Zbtb20	A	G	16: 43,618,692 (GRCm38)	D725G	probably damaging	Het
Zfp341	A	T	2: 154,626,814 (GRCm38)	I126F	possibly damaging	Het
Zfyve16	C	T	13: 92,513,894 (GRCm38)	A861T	probably damaging	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,417,060 (GRCm38)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,236,025 (GRCm38)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,279,042 (GRCm38)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,276,421 (GRCm38)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,417,132 (GRCm38)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,256,841 (GRCm38)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,236,423 (GRCm38)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,276,645 (GRCm38)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,228,802 (GRCm38)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,254,477 (GRCm38)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,236,758 (GRCm38)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,276,396 (GRCm38)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,276,576 (GRCm38)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,235,476 (GRCm38)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,236,694 (GRCm38)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,279,198 (GRCm38)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,288,016 (GRCm38)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,299,639 (GRCm38)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,298,956 (GRCm38)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,276,903 (GRCm38)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,298,878 (GRCm38)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	48,646,418 (GRCm38)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,235,523 (GRCm38)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,235,346 (GRCm38)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,235,607 (GRCm38)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,293,657 (GRCm38)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,343,345 (GRCm38)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,342,659 (GRCm38)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,341,034 (GRCm38)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,236,912 (GRCm38)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,232,105 (GRCm38)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,228,975 (GRCm38)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,287,791 (GRCm38)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,341,160 (GRCm38)	splice site	probably benign
R0573:Tenm3	UTSW	8	48,674,399 (GRCm38)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,277,710 (GRCm38)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,276,156 (GRCm38)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,236,525 (GRCm38)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,236,594 (GRCm38)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,335,742 (GRCm38)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,298,965 (GRCm38)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,228,542 (GRCm38)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,235,582 (GRCm38)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,240,396 (GRCm38)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,287,893 (GRCm38)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,276,400 (GRCm38)	missense	probably benign
R1455:Tenm3	UTSW	8	48,279,048 (GRCm38)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,235,971 (GRCm38)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,310,625 (GRCm38)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,343,316 (GRCm38)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,287,822 (GRCm38)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,395,576 (GRCm38)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,228,981 (GRCm38)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,236,421 (GRCm38)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,228,993 (GRCm38)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,279,074 (GRCm38)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,417,119 (GRCm38)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,310,634 (GRCm38)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,232,104 (GRCm38)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,417,179 (GRCm38)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	48,674,544 (GRCm38)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,276,256 (GRCm38)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,276,346 (GRCm38)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,310,761 (GRCm38)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,236,313 (GRCm38)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,228,591 (GRCm38)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,228,668 (GRCm38)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,342,256 (GRCm38)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,343,349 (GRCm38)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,417,006 (GRCm38)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,395,544 (GRCm38)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	48,674,550 (GRCm38)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,342,337 (GRCm38)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,287,953 (GRCm38)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,240,270 (GRCm38)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,228,555 (GRCm38)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,277,746 (GRCm38)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,349,223 (GRCm38)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,349,404 (GRCm38)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,395,658 (GRCm38)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,293,726 (GRCm38)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,235,970 (GRCm38)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,310,621 (GRCm38)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,235,821 (GRCm38)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,276,861 (GRCm38)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,300,971 (GRCm38)	missense	probably damaging	1.00
R4995:Tenm3	UTSW	8	48,229,137 (GRCm38)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,235,826 (GRCm38)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,342,308 (GRCm38)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,229,198 (GRCm38)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,236,855 (GRCm38)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,287,831 (GRCm38)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,236,564 (GRCm38)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,367,377 (GRCm38)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,279,006 (GRCm38)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,236,764 (GRCm38)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,228,762 (GRCm38)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	48,646,498 (GRCm38)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	48,646,447 (GRCm38)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,228,508 (GRCm38)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,343,406 (GRCm38)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,395,573 (GRCm38)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,298,808 (GRCm38)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,254,622 (GRCm38)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,293,665 (GRCm38)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,417,059 (GRCm38)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,367,394 (GRCm38)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,276,849 (GRCm38)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,236,063 (GRCm38)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6516:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6747:Tenm3	UTSW	8	48,343,243 (GRCm38)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	48,646,256 (GRCm38)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	48,674,493 (GRCm38)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,256,837 (GRCm38)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,276,738 (GRCm38)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	48,674,416 (GRCm38)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,240,479 (GRCm38)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,240,444 (GRCm38)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	48,674,553 (GRCm38)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,292,236 (GRCm38)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,300,969 (GRCm38)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,235,935 (GRCm38)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,236,177 (GRCm38)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,236,183 (GRCm38)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,287,812 (GRCm38)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,276,600 (GRCm38)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,341,049 (GRCm38)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,335,727 (GRCm38)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	48,646,333 (GRCm38)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,236,465 (GRCm38)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,276,300 (GRCm38)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,229,111 (GRCm38)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,310,703 (GRCm38)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,367,422 (GRCm38)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,293,773 (GRCm38)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,287,848 (GRCm38)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,293,509 (GRCm38)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,229,181 (GRCm38)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,342,633 (GRCm38)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,299,645 (GRCm38)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,349,356 (GRCm38)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,342,449 (GRCm38)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,310,724 (GRCm38)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8831:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8853:Tenm3	UTSW	8	48,342,347 (GRCm38)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,236,402 (GRCm38)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,235,602 (GRCm38)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,279,060 (GRCm38)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,235,348 (GRCm38)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,276,687 (GRCm38)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,342,653 (GRCm38)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,254,633 (GRCm38)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,292,151 (GRCm38)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,335,513 (GRCm38)	missense	unknown
R9231:Tenm3	UTSW	8	48,236,196 (GRCm38)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	48,555,900 (GRCm38)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,417,080 (GRCm38)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,299,655 (GRCm38)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	48,674,524 (GRCm38)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,313,257 (GRCm38)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,235,761 (GRCm38)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,236,211 (GRCm38)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,300,814 (GRCm38)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,335,561 (GRCm38)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,287,829 (GRCm38)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,236,477 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,276,780 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CAGTAGATGTGATGCAGCTTTC -3'
(R):5'- TTTACAGTAGCAACCCAGCTC -3'

Sequencing Primer
(F):5'- TGTGATGCAGCTTTCAAGAACACG -3'
(R):5'- CAGTCACCGGAGATTTGTACGTC -3'

Posted On

2016-04-27