Incidental Mutation 'R4952:Heatr1'
| ID |
382087 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Heatr1
|
| Ensembl Gene |
ENSMUSG00000050244 |
| Gene Name |
HEAT repeat containing 1 |
| Synonyms |
B130016L12Rik |
| MMRRC Submission |
042549-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.964)
|
| Stock # |
R4952 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
12410256-12453774 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 12425480 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Leucine
at position 640
(W640L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000054084
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000059270]
[ENSMUST00000221046]
|
| AlphaFold |
G3X9B1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000059270
AA Change: W640L
PolyPhen 2
Score 0.384 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000054084
Gene: ENSMUSG00000050244
AA Change: W640L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
15 |
N/A |
INTRINSIC |
|
Pfam:U3snoRNP10
|
238 |
354 |
7e-30 |
PFAM |
|
SCOP:d1qbkb_
|
919 |
1795 |
3e-8 |
SMART |
|
low complexity region
|
1805 |
1814 |
N/A |
INTRINSIC |
|
BP28CT
|
1856 |
2009 |
2.25e-77 |
SMART |
|
Blast:BP28CT
|
2015 |
2061 |
2e-15 |
BLAST |
|
coiled coil region
|
2109 |
2137 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000221046
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000221746
|
| Meta Mutation Damage Score |
0.1265 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.3%
- 10x: 96.5%
- 20x: 93.0%
|
| Validation Efficiency |
99% (93/94) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522L14Rik |
A |
G |
5: 109,887,063 (GRCm39) |
|
probably null |
Het |
| 4933421I07Rik |
T |
C |
7: 42,097,083 (GRCm39) |
Y76C |
possibly damaging |
Het |
| Adcy4 |
C |
T |
14: 56,016,486 (GRCm39) |
D322N |
probably damaging |
Het |
| Ak9 |
A |
G |
10: 41,296,585 (GRCm39) |
M1444V |
probably benign |
Het |
| Amfr |
A |
G |
8: 94,699,787 (GRCm39) |
|
probably benign |
Het |
| Ankef1 |
A |
G |
2: 136,392,449 (GRCm39) |
E546G |
probably damaging |
Het |
| Ankrd24 |
A |
G |
10: 81,482,982 (GRCm39) |
M977V |
probably benign |
Het |
| Ap3m1 |
A |
T |
14: 21,090,134 (GRCm39) |
S5T |
probably benign |
Het |
| Aqr |
C |
A |
2: 113,940,418 (GRCm39) |
D1243Y |
probably damaging |
Het |
| Arhgef2 |
T |
C |
3: 88,549,769 (GRCm39) |
L591P |
probably damaging |
Het |
| Arid4a |
C |
A |
12: 71,070,299 (GRCm39) |
T70K |
possibly damaging |
Het |
| Asphd1 |
C |
T |
7: 126,547,857 (GRCm39) |
A149T |
probably benign |
Het |
| Avpr1a |
T |
A |
10: 122,285,659 (GRCm39) |
M317K |
probably damaging |
Het |
| Birc2 |
T |
C |
9: 7,836,741 (GRCm39) |
I109V |
probably damaging |
Het |
| Catsperd |
A |
G |
17: 56,939,303 (GRCm39) |
Y44C |
probably damaging |
Het |
| Crygb |
T |
G |
1: 65,121,268 (GRCm39) |
S20R |
probably benign |
Het |
| Cyp3a25 |
T |
C |
5: 145,928,334 (GRCm39) |
N237S |
probably benign |
Het |
| Dkk3 |
C |
T |
7: 111,717,558 (GRCm39) |
A304T |
probably benign |
Het |
| Dst |
T |
C |
1: 34,310,503 (GRCm39) |
L4101S |
probably damaging |
Het |
| Dysf |
A |
G |
6: 84,126,968 (GRCm39) |
N1407S |
possibly damaging |
Het |
| Epb41 |
A |
G |
4: 131,727,581 (GRCm39) |
V265A |
probably damaging |
Het |
| Faim2 |
C |
T |
15: 99,419,109 (GRCm39) |
E75K |
possibly damaging |
Het |
| Fam237b |
T |
A |
5: 5,625,387 (GRCm39) |
F28I |
probably benign |
Het |
| Fbn1 |
T |
A |
2: 125,159,454 (GRCm39) |
D2208V |
probably damaging |
Het |
| Fbxo28 |
A |
G |
1: 182,153,950 (GRCm39) |
S129P |
probably damaging |
Het |
| Fbxw14 |
T |
A |
9: 109,105,269 (GRCm39) |
I299L |
probably benign |
Het |
| Fras1 |
C |
T |
5: 96,795,357 (GRCm39) |
A1050V |
probably benign |
Het |
| Fyb1 |
C |
A |
15: 6,668,292 (GRCm39) |
T495K |
probably damaging |
Het |
| Ghdc |
A |
T |
11: 100,659,977 (GRCm39) |
W257R |
probably damaging |
Het |
| Gm10719 |
T |
C |
9: 3,018,962 (GRCm39) |
L69S |
probably benign |
Het |
| Gm12250 |
G |
T |
11: 58,079,210 (GRCm39) |
|
noncoding transcript |
Het |
| Gm4846 |
A |
T |
1: 166,311,503 (GRCm39) |
F452Y |
probably damaging |
Het |
| Gpbp1 |
T |
C |
13: 111,577,284 (GRCm39) |
D202G |
probably damaging |
Het |
| Gpd2 |
C |
A |
2: 57,197,025 (GRCm39) |
Y193* |
probably null |
Het |
| Grhl2 |
G |
T |
15: 37,287,493 (GRCm39) |
R229L |
probably benign |
Het |
| Gtf2a1 |
A |
G |
12: 91,542,523 (GRCm39) |
F59L |
possibly damaging |
Het |
| Kalrn |
A |
T |
16: 34,177,785 (GRCm39) |
|
probably null |
Het |
| Keap1 |
T |
C |
9: 21,148,582 (GRCm39) |
T142A |
probably damaging |
Het |
| Kpna2 |
G |
A |
11: 106,882,061 (GRCm39) |
T255M |
probably damaging |
Het |
| Kpna3 |
A |
G |
14: 61,607,838 (GRCm39) |
C456R |
probably damaging |
Het |
| Lama1 |
G |
A |
17: 68,074,561 (GRCm39) |
|
probably null |
Het |
| Lrrc37 |
T |
C |
11: 103,505,033 (GRCm39) |
T2312A |
possibly damaging |
Het |
| Mag |
C |
A |
7: 30,608,581 (GRCm39) |
E178* |
probably null |
Het |
| Map3k13 |
A |
G |
16: 21,729,769 (GRCm39) |
I467V |
probably benign |
Het |
| Mga |
A |
G |
2: 119,733,782 (GRCm39) |
E210G |
probably damaging |
Het |
| Msi2 |
C |
T |
11: 88,257,610 (GRCm39) |
|
probably null |
Het |
| Naa16 |
A |
T |
14: 79,582,525 (GRCm39) |
D521E |
probably damaging |
Het |
| Nav2 |
C |
T |
7: 48,954,288 (GRCm39) |
|
probably benign |
Het |
| Nek10 |
T |
A |
14: 14,860,986 (GRCm38) |
L513M |
possibly damaging |
Het |
| Nek5 |
T |
C |
8: 22,586,815 (GRCm39) |
K332R |
probably benign |
Het |
| Nek5 |
T |
A |
8: 22,569,104 (GRCm39) |
I573L |
probably benign |
Het |
| Ntn1 |
CCTTCTTCT |
CCTTCT |
11: 68,103,852 (GRCm39) |
|
probably benign |
Het |
| Odad1 |
A |
C |
7: 45,591,615 (GRCm39) |
E293A |
probably damaging |
Het |
| Or2w1 |
G |
A |
13: 21,317,514 (GRCm39) |
V190I |
probably benign |
Het |
| Or5v1b |
A |
T |
17: 37,841,641 (GRCm39) |
T258S |
possibly damaging |
Het |
| Or6c204 |
T |
A |
10: 129,022,466 (GRCm39) |
T275S |
probably benign |
Het |
| Or8b12b |
T |
A |
9: 37,684,360 (GRCm39) |
M135K |
probably damaging |
Het |
| Orai1 |
T |
G |
5: 123,167,313 (GRCm39) |
V162G |
probably damaging |
Het |
| P2rx6 |
T |
C |
16: 17,385,308 (GRCm39) |
S134P |
probably damaging |
Het |
| Pappa2 |
G |
A |
1: 158,684,706 (GRCm39) |
T811I |
probably null |
Het |
| Pcdhga10 |
T |
C |
18: 37,880,213 (GRCm39) |
|
probably benign |
Het |
| Pex16 |
C |
T |
2: 92,209,405 (GRCm39) |
R241* |
probably null |
Het |
| Plxnb1 |
T |
C |
9: 108,943,904 (GRCm39) |
F1969L |
probably damaging |
Het |
| Postn |
A |
G |
3: 54,297,736 (GRCm39) |
|
probably benign |
Het |
| Prdm15 |
A |
T |
16: 97,607,277 (GRCm39) |
I752N |
probably damaging |
Het |
| Rasgef1c |
A |
T |
11: 49,870,339 (GRCm39) |
K468M |
probably damaging |
Het |
| Rbfox1 |
A |
G |
16: 7,094,952 (GRCm39) |
S111G |
probably benign |
Het |
| Rbm28 |
T |
C |
6: 29,138,597 (GRCm39) |
D405G |
probably damaging |
Het |
| Rell1 |
A |
G |
5: 64,097,010 (GRCm39) |
|
probably benign |
Het |
| Rfx3 |
A |
G |
19: 27,808,072 (GRCm39) |
S224P |
probably damaging |
Het |
| Scarb2 |
A |
T |
5: 92,602,636 (GRCm39) |
I260K |
probably damaging |
Het |
| Septin4 |
A |
G |
11: 87,458,598 (GRCm39) |
N324S |
probably benign |
Het |
| Slc15a4 |
A |
G |
5: 127,680,901 (GRCm39) |
F72L |
probably damaging |
Het |
| Spg7 |
C |
A |
8: 123,816,910 (GRCm39) |
R534S |
probably damaging |
Het |
| Stoml2 |
T |
C |
4: 43,029,589 (GRCm39) |
T164A |
probably benign |
Het |
| Syt11 |
C |
T |
3: 88,669,590 (GRCm39) |
G101S |
possibly damaging |
Het |
| Traj12 |
A |
G |
14: 54,444,013 (GRCm39) |
|
probably benign |
Het |
| Traj7 |
A |
T |
14: 54,448,981 (GRCm39) |
|
probably benign |
Het |
| Tysnd1 |
C |
T |
10: 61,537,855 (GRCm39) |
T175I |
possibly damaging |
Het |
| Usp48 |
T |
G |
4: 137,334,004 (GRCm39) |
Y139* |
probably null |
Het |
| Vmn2r72 |
A |
G |
7: 85,400,317 (GRCm39) |
L244P |
probably benign |
Het |
| Wasf1 |
C |
A |
10: 40,812,186 (GRCm39) |
P325Q |
unknown |
Het |
| Zc3h18 |
T |
A |
8: 123,137,639 (GRCm39) |
|
probably benign |
Het |
| Zfp712 |
A |
G |
13: 67,188,905 (GRCm39) |
S541P |
possibly damaging |
Het |
|
| Other mutations in Heatr1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00666:Heatr1
|
APN |
13 |
12,425,331 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00863:Heatr1
|
APN |
13 |
12,450,009 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00899:Heatr1
|
APN |
13 |
12,450,057 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL01147:Heatr1
|
APN |
13 |
12,452,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01317:Heatr1
|
APN |
13 |
12,413,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01323:Heatr1
|
APN |
13 |
12,413,819 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL01625:Heatr1
|
APN |
13 |
12,428,409 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01973:Heatr1
|
APN |
13 |
12,444,680 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Heatr1
|
APN |
13 |
12,448,867 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02830:Heatr1
|
APN |
13 |
12,441,093 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02956:Heatr1
|
APN |
13 |
12,430,940 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL03000:Heatr1
|
APN |
13 |
12,449,292 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03024:Heatr1
|
APN |
13 |
12,422,390 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03035:Heatr1
|
APN |
13 |
12,428,100 (GRCm39) |
splice site |
probably benign |
|
|
IGL03301:Heatr1
|
APN |
13 |
12,449,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
hasan
|
UTSW |
13 |
12,432,328 (GRCm39) |
splice site |
probably benign |
|
|
H8562:Heatr1
|
UTSW |
13 |
12,423,594 (GRCm39) |
missense |
probably benign |
0.13 |
|
R0226:Heatr1
|
UTSW |
13 |
12,425,443 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0571:Heatr1
|
UTSW |
13 |
12,445,121 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0722:Heatr1
|
UTSW |
13 |
12,420,918 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1264:Heatr1
|
UTSW |
13 |
12,439,491 (GRCm39) |
unclassified |
probably benign |
|
|
R1371:Heatr1
|
UTSW |
13 |
12,432,513 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1388:Heatr1
|
UTSW |
13 |
12,432,328 (GRCm39) |
splice site |
probably benign |
|
|
R1396:Heatr1
|
UTSW |
13 |
12,420,927 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1519:Heatr1
|
UTSW |
13 |
12,427,040 (GRCm39) |
missense |
probably benign |
|
|
R1689:Heatr1
|
UTSW |
13 |
12,439,506 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1696:Heatr1
|
UTSW |
13 |
12,438,602 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1756:Heatr1
|
UTSW |
13 |
12,411,341 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1859:Heatr1
|
UTSW |
13 |
12,418,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1932:Heatr1
|
UTSW |
13 |
12,450,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Heatr1
|
UTSW |
13 |
12,411,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2018:Heatr1
|
UTSW |
13 |
12,429,359 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2106:Heatr1
|
UTSW |
13 |
12,426,939 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2119:Heatr1
|
UTSW |
13 |
12,447,527 (GRCm39) |
missense |
probably null |
1.00 |
|
R2121:Heatr1
|
UTSW |
13 |
12,418,145 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2122:Heatr1
|
UTSW |
13 |
12,418,145 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2367:Heatr1
|
UTSW |
13 |
12,448,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3777:Heatr1
|
UTSW |
13 |
12,428,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3783:Heatr1
|
UTSW |
13 |
12,449,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Heatr1
|
UTSW |
13 |
12,449,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3786:Heatr1
|
UTSW |
13 |
12,449,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3787:Heatr1
|
UTSW |
13 |
12,449,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3843:Heatr1
|
UTSW |
13 |
12,450,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4533:Heatr1
|
UTSW |
13 |
12,449,392 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4725:Heatr1
|
UTSW |
13 |
12,439,543 (GRCm39) |
nonsense |
probably null |
|
|
R4763:Heatr1
|
UTSW |
13 |
12,445,811 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4793:Heatr1
|
UTSW |
13 |
12,446,718 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4797:Heatr1
|
UTSW |
13 |
12,426,929 (GRCm39) |
missense |
probably benign |
0.36 |
|
R4798:Heatr1
|
UTSW |
13 |
12,426,929 (GRCm39) |
missense |
probably benign |
0.36 |
|
R4942:Heatr1
|
UTSW |
13 |
12,428,391 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4954:Heatr1
|
UTSW |
13 |
12,422,397 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5370:Heatr1
|
UTSW |
13 |
12,416,403 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5464:Heatr1
|
UTSW |
13 |
12,448,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5483:Heatr1
|
UTSW |
13 |
12,413,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5497:Heatr1
|
UTSW |
13 |
12,435,945 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5504:Heatr1
|
UTSW |
13 |
12,421,500 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R5527:Heatr1
|
UTSW |
13 |
12,419,829 (GRCm39) |
missense |
probably benign |
|
|
R5527:Heatr1
|
UTSW |
13 |
12,417,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5836:Heatr1
|
UTSW |
13 |
12,423,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5916:Heatr1
|
UTSW |
13 |
12,449,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6018:Heatr1
|
UTSW |
13 |
12,420,939 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6018:Heatr1
|
UTSW |
13 |
12,419,828 (GRCm39) |
missense |
probably benign |
|
|
R6216:Heatr1
|
UTSW |
13 |
12,447,545 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6396:Heatr1
|
UTSW |
13 |
12,420,978 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6472:Heatr1
|
UTSW |
13 |
12,449,111 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6922:Heatr1
|
UTSW |
13 |
12,449,956 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7077:Heatr1
|
UTSW |
13 |
12,433,045 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7297:Heatr1
|
UTSW |
13 |
12,435,941 (GRCm39) |
nonsense |
probably null |
|
|
R7445:Heatr1
|
UTSW |
13 |
12,445,919 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7669:Heatr1
|
UTSW |
13 |
12,426,143 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7672:Heatr1
|
UTSW |
13 |
12,453,545 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7772:Heatr1
|
UTSW |
13 |
12,432,522 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8205:Heatr1
|
UTSW |
13 |
12,430,928 (GRCm39) |
missense |
probably benign |
|
|
R8518:Heatr1
|
UTSW |
13 |
12,425,415 (GRCm39) |
missense |
probably benign |
|
|
R8754:Heatr1
|
UTSW |
13 |
12,428,175 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8874:Heatr1
|
UTSW |
13 |
12,445,793 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8992:Heatr1
|
UTSW |
13 |
12,415,995 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9045:Heatr1
|
UTSW |
13 |
12,428,233 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9077:Heatr1
|
UTSW |
13 |
12,428,247 (GRCm39) |
missense |
probably benign |
|
|
R9183:Heatr1
|
UTSW |
13 |
12,436,266 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9186:Heatr1
|
UTSW |
13 |
12,436,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Heatr1
|
UTSW |
13 |
12,419,802 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9242:Heatr1
|
UTSW |
13 |
12,448,806 (GRCm39) |
missense |
probably benign |
|
|
R9267:Heatr1
|
UTSW |
13 |
12,421,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9289:Heatr1
|
UTSW |
13 |
12,447,608 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9310:Heatr1
|
UTSW |
13 |
12,453,491 (GRCm39) |
missense |
probably benign |
|
|
R9312:Heatr1
|
UTSW |
13 |
12,446,565 (GRCm39) |
missense |
probably benign |
|
|
R9358:Heatr1
|
UTSW |
13 |
12,433,087 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9385:Heatr1
|
UTSW |
13 |
12,421,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9530:Heatr1
|
UTSW |
13 |
12,439,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9532:Heatr1
|
UTSW |
13 |
12,429,306 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9647:Heatr1
|
UTSW |
13 |
12,441,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9683:Heatr1
|
UTSW |
13 |
12,449,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9695:Heatr1
|
UTSW |
13 |
12,438,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF011:Heatr1
|
UTSW |
13 |
12,422,425 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Heatr1
|
UTSW |
13 |
12,413,889 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCTTGAGCTAGCAGCAAAC -3'
(R):5'- GTTATAACTCTCAGCCATGGTCTC -3'
Sequencing Primer
(F):5'- GCTAGCAGCAAACATACTAATTAAAG -3'
(R):5'- GACTGCTCTTCCAAAGGTCATGAG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation