Incidental Mutation 'R4959:Thada'
| ID |
382212 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
042556-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4959 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 84751611 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 455
(Y455C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047524
AA Change: Y455C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: Y455C
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.6%
- 20x: 89.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| 6820408C15Rik |
T |
A |
2: 152,282,808 (GRCm39) |
I221K |
possibly damaging |
Het |
| Aadacl3 |
A |
T |
4: 144,183,656 (GRCm39) |
C136S |
probably benign |
Het |
| Abhd16a |
T |
A |
17: 35,321,318 (GRCm39) |
S498T |
probably benign |
Het |
| Acrv1 |
G |
A |
9: 36,605,996 (GRCm39) |
|
probably null |
Het |
| Adamts18 |
G |
A |
8: 114,463,357 (GRCm39) |
R830* |
probably null |
Het |
| Art3 |
A |
G |
5: 92,551,478 (GRCm39) |
Y279C |
probably damaging |
Het |
| Atm |
A |
T |
9: 53,426,601 (GRCm39) |
D552E |
probably benign |
Het |
| Ccdc154 |
T |
C |
17: 25,389,888 (GRCm39) |
L508P |
probably damaging |
Het |
| Ccser2 |
A |
T |
14: 36,662,753 (GRCm39) |
S144T |
probably benign |
Het |
| Cgn |
C |
T |
3: 94,685,564 (GRCm39) |
A320T |
probably benign |
Het |
| Cklf |
A |
G |
8: 104,988,184 (GRCm39) |
K106E |
probably benign |
Het |
| Clec12a |
C |
A |
6: 129,330,628 (GRCm39) |
T70K |
probably benign |
Het |
| CN725425 |
G |
A |
15: 91,129,904 (GRCm39) |
A256T |
possibly damaging |
Het |
| Crb2 |
G |
T |
2: 37,680,482 (GRCm39) |
R470L |
probably damaging |
Het |
| Csn1s1 |
T |
G |
5: 87,821,120 (GRCm39) |
S33A |
probably benign |
Het |
| D630045J12Rik |
C |
T |
6: 38,125,302 (GRCm39) |
V1571M |
possibly damaging |
Het |
| Deup1 |
G |
A |
9: 15,523,310 (GRCm39) |
Q58* |
probably null |
Het |
| Dph2 |
T |
A |
4: 117,748,527 (GRCm39) |
D82V |
probably damaging |
Het |
| Dsp |
C |
T |
13: 38,375,686 (GRCm39) |
A1157V |
probably benign |
Het |
| Evi5l |
G |
T |
8: 4,255,406 (GRCm39) |
V477L |
probably benign |
Het |
| Fam187b |
T |
A |
7: 30,681,687 (GRCm39) |
H131Q |
probably damaging |
Het |
| Fam193b |
A |
G |
13: 55,691,097 (GRCm39) |
I259T |
probably damaging |
Het |
| Fam91a1 |
A |
G |
15: 58,303,059 (GRCm39) |
T323A |
probably benign |
Het |
| Fat4 |
T |
G |
3: 39,037,195 (GRCm39) |
S3616A |
probably benign |
Het |
| Fbxo38 |
A |
T |
18: 62,655,578 (GRCm39) |
N369K |
probably benign |
Het |
| Fitm1 |
T |
A |
14: 55,813,831 (GRCm39) |
|
probably null |
Het |
| Fkbp5 |
T |
C |
17: 28,647,343 (GRCm39) |
E164G |
probably damaging |
Het |
| Fpr-rs3 |
T |
C |
17: 20,844,211 (GRCm39) |
Y310C |
possibly damaging |
Het |
| Fryl |
A |
T |
5: 73,192,401 (GRCm39) |
M2678K |
probably benign |
Het |
| Fsip2 |
T |
C |
2: 82,815,169 (GRCm39) |
I3634T |
probably benign |
Het |
| Gm3233 |
T |
C |
10: 77,595,399 (GRCm39) |
|
probably benign |
Het |
| Gzmd |
T |
G |
14: 56,369,955 (GRCm39) |
T9P |
unknown |
Het |
| Htr2b |
A |
T |
1: 86,027,813 (GRCm39) |
I231N |
probably damaging |
Het |
| Il2ra |
A |
G |
2: 11,681,664 (GRCm39) |
T90A |
possibly damaging |
Het |
| Kbtbd2 |
A |
G |
6: 56,758,943 (GRCm39) |
F60S |
probably benign |
Het |
| Kif21b |
G |
A |
1: 136,076,108 (GRCm39) |
C299Y |
possibly damaging |
Het |
| Lsm5 |
A |
T |
6: 56,680,309 (GRCm39) |
D44E |
probably damaging |
Het |
| Mapk1 |
T |
A |
16: 16,836,170 (GRCm39) |
M106K |
probably damaging |
Het |
| Mpp2 |
A |
G |
11: 101,954,117 (GRCm39) |
V193A |
probably damaging |
Het |
| Muc4 |
T |
C |
16: 32,575,437 (GRCm39) |
S1398P |
possibly damaging |
Het |
| Ndufs2 |
A |
G |
1: 171,065,578 (GRCm39) |
Y282H |
probably damaging |
Het |
| Nes |
T |
A |
3: 87,882,983 (GRCm39) |
L414Q |
probably damaging |
Het |
| Neurl2 |
T |
A |
2: 164,675,122 (GRCm39) |
|
probably null |
Het |
| Ngef |
A |
G |
1: 87,431,070 (GRCm39) |
F159S |
possibly damaging |
Het |
| Nlrx1 |
T |
C |
9: 44,165,448 (GRCm39) |
H816R |
possibly damaging |
Het |
| Or10v5 |
A |
G |
19: 11,806,300 (GRCm39) |
L30P |
probably benign |
Het |
| Or1e22 |
A |
T |
11: 73,376,893 (GRCm39) |
Y252* |
probably null |
Het |
| Or2f1 |
T |
C |
6: 42,721,621 (GRCm39) |
S217P |
probably damaging |
Het |
| Or4c106 |
T |
C |
2: 88,682,516 (GRCm39) |
V74A |
possibly damaging |
Het |
| Or4f17-ps1 |
T |
A |
2: 111,357,969 (GRCm39) |
F103L |
probably damaging |
Het |
| Or4p7 |
T |
A |
2: 88,221,674 (GRCm39) |
L28I |
probably benign |
Het |
| Or7g35 |
A |
G |
9: 19,496,504 (GRCm39) |
T224A |
probably benign |
Het |
| Pcgf2 |
A |
T |
11: 97,582,515 (GRCm39) |
Y7N |
possibly damaging |
Het |
| Pdlim5 |
G |
A |
3: 142,017,740 (GRCm39) |
|
probably benign |
Het |
| Pdzd2 |
A |
G |
15: 12,375,734 (GRCm39) |
V1467A |
probably damaging |
Het |
| Pigp |
C |
A |
16: 94,160,006 (GRCm39) |
G134V |
probably benign |
Het |
| Pik3c2g |
T |
C |
6: 139,789,657 (GRCm39) |
Y385H |
possibly damaging |
Het |
| Pnliprp2 |
G |
A |
19: 58,754,750 (GRCm39) |
E265K |
probably benign |
Het |
| Prl3c1 |
G |
T |
13: 27,386,471 (GRCm39) |
|
probably null |
Het |
| Ptpn4 |
A |
T |
1: 119,692,826 (GRCm39) |
Y110* |
probably null |
Het |
| Ptprq |
C |
T |
10: 107,522,416 (GRCm39) |
V546I |
probably damaging |
Het |
| Rd3l |
C |
T |
12: 111,946,578 (GRCm39) |
|
probably null |
Het |
| Rpl37 |
G |
A |
15: 5,147,128 (GRCm39) |
R56Q |
possibly damaging |
Het |
| Rttn |
A |
T |
18: 89,060,292 (GRCm39) |
H998L |
probably damaging |
Het |
| Rufy1 |
A |
T |
11: 50,292,315 (GRCm39) |
F491L |
probably benign |
Het |
| Simc1 |
T |
G |
13: 54,673,131 (GRCm39) |
V493G |
possibly damaging |
Het |
| Slc22a14 |
CTTTCCTGAA |
C |
9: 119,003,101 (GRCm39) |
|
probably benign |
Het |
| Slc25a46 |
A |
T |
18: 31,735,807 (GRCm39) |
I144N |
possibly damaging |
Het |
| Smtn |
A |
T |
11: 3,477,825 (GRCm39) |
M1K |
probably null |
Het |
| Snd1 |
C |
A |
6: 28,884,250 (GRCm39) |
Y766* |
probably null |
Het |
| Spata31d1d |
C |
T |
13: 59,875,102 (GRCm39) |
G811D |
probably damaging |
Het |
| Spta1 |
A |
C |
1: 174,074,174 (GRCm39) |
D2371A |
probably damaging |
Het |
| Stard6 |
A |
C |
18: 70,631,631 (GRCm39) |
D74A |
possibly damaging |
Het |
| Stim2 |
G |
T |
5: 54,262,712 (GRCm39) |
R318L |
probably benign |
Het |
| Sufu |
C |
T |
19: 46,463,991 (GRCm39) |
T401I |
possibly damaging |
Het |
| Suz12 |
G |
A |
11: 79,920,057 (GRCm39) |
G539D |
probably damaging |
Het |
| Sytl2 |
C |
G |
7: 90,025,245 (GRCm39) |
S411C |
probably damaging |
Het |
| Taf6 |
G |
A |
5: 138,181,465 (GRCm39) |
Q156* |
probably null |
Het |
| Tead4 |
T |
C |
6: 128,247,950 (GRCm39) |
D29G |
probably damaging |
Het |
| Tlr6 |
G |
C |
5: 65,111,002 (GRCm39) |
T635S |
possibly damaging |
Het |
| Tlr9 |
A |
G |
9: 106,101,876 (GRCm39) |
D389G |
probably benign |
Het |
| Tmem54 |
A |
T |
4: 129,002,073 (GRCm39) |
H40L |
probably damaging |
Het |
| Trappc9 |
G |
T |
15: 72,808,905 (GRCm39) |
N540K |
probably damaging |
Het |
| Trbv28 |
C |
T |
6: 41,248,788 (GRCm39) |
S106F |
probably damaging |
Het |
| Trrap |
A |
T |
5: 144,793,770 (GRCm39) |
H3384L |
probably damaging |
Het |
| Usp16 |
T |
A |
16: 87,277,802 (GRCm39) |
M684K |
probably damaging |
Het |
| Vat1 |
G |
A |
11: 101,351,426 (GRCm39) |
T305M |
probably damaging |
Het |
| Vmn2r85 |
A |
G |
10: 130,257,302 (GRCm39) |
S544P |
probably damaging |
Het |
| Vps8 |
T |
C |
16: 21,278,536 (GRCm39) |
S267P |
probably damaging |
Het |
| Ylpm1 |
T |
A |
12: 85,096,719 (GRCm39) |
V1242E |
probably damaging |
Het |
| Zfp267 |
C |
T |
3: 36,218,285 (GRCm39) |
R102C |
possibly damaging |
Het |
| Zfp322a |
T |
C |
13: 23,541,052 (GRCm39) |
Y230C |
probably damaging |
Het |
| Zfp352 |
T |
A |
4: 90,112,376 (GRCm39) |
V172E |
probably benign |
Het |
| Zfp936 |
A |
T |
7: 42,839,034 (GRCm39) |
H167L |
probably damaging |
Het |
| Zkscan14 |
A |
G |
5: 145,132,302 (GRCm39) |
Y410H |
probably benign |
Het |
| Zkscan17 |
A |
G |
11: 59,394,538 (GRCm39) |
M21T |
probably damaging |
Het |
| Zswim4 |
G |
T |
8: 84,938,852 (GRCm39) |
A1010D |
probably benign |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAGTTTGGGACTTCAAATGGC -3'
(R):5'- CATCTGAACGGGGACTCATG -3'
Sequencing Primer
(F):5'- GGGACTTCAAATGGCTCTTATG -3'
(R):5'- GACTCATGCGTACCTAGGAGACTTC -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation