Incidental Mutation 'R4960:Clip1'
| ID |
382261 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| MMRRC Submission |
042557-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4960 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 123792066 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Stop codon
at position 35
(K35*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115965
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000031382
AA Change: K35*
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
AA Change: K35*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000063905
AA Change: K35*
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
AA Change: K35*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000111561
AA Change: K35*
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
AA Change: K35*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000111564
AA Change: K35*
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
AA Change: K35*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000111566
AA Change: K35*
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
AA Change: K35*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000144121
AA Change: K11*
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
AA Change: K11*
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000149410
AA Change: K35*
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
AA Change: K35*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc9 |
A |
T |
6: 142,566,509 (GRCm39) |
|
probably null |
Het |
| Abtb3 |
A |
C |
10: 85,487,526 (GRCm39) |
N998T |
probably benign |
Het |
| Adamts20 |
T |
C |
15: 94,277,655 (GRCm39) |
H269R |
probably benign |
Het |
| Adamtsl1 |
C |
T |
4: 86,342,410 (GRCm39) |
Q1642* |
probably null |
Het |
| Adamtsl3 |
A |
C |
7: 82,216,185 (GRCm39) |
T863P |
probably damaging |
Het |
| Adcy3 |
G |
T |
12: 4,184,896 (GRCm39) |
V191L |
probably benign |
Het |
| Akap9 |
G |
T |
5: 4,007,664 (GRCm39) |
R244L |
probably benign |
Het |
| Anapc1 |
C |
T |
2: 128,526,514 (GRCm39) |
V95M |
probably benign |
Het |
| Arhgap17 |
G |
T |
7: 122,886,149 (GRCm39) |
|
probably benign |
Het |
| Art2b |
T |
A |
7: 101,229,437 (GRCm39) |
Y154F |
probably damaging |
Het |
| Atrn |
C |
T |
2: 130,836,967 (GRCm39) |
R1144* |
probably null |
Het |
| Atxn3 |
T |
C |
12: 101,914,638 (GRCm39) |
S29G |
possibly damaging |
Het |
| Batf3 |
C |
T |
1: 190,830,707 (GRCm39) |
P18S |
probably benign |
Het |
| Bmal1 |
T |
A |
7: 112,898,642 (GRCm39) |
|
probably null |
Het |
| Bmpr1b |
A |
T |
3: 141,576,546 (GRCm39) |
C96S |
probably damaging |
Het |
| Bola1 |
A |
G |
3: 96,104,370 (GRCm39) |
S75P |
probably benign |
Het |
| Cela3a |
G |
A |
4: 137,129,959 (GRCm39) |
R221* |
probably null |
Het |
| Chat |
A |
G |
14: 32,142,771 (GRCm39) |
V406A |
possibly damaging |
Het |
| Chd1 |
T |
A |
17: 15,962,493 (GRCm39) |
M750K |
probably damaging |
Het |
| Cnr2 |
G |
A |
4: 135,644,918 (GRCm39) |
G332D |
probably benign |
Het |
| Cnrip1 |
A |
G |
11: 17,002,228 (GRCm39) |
D20G |
probably damaging |
Het |
| Col2a1 |
T |
C |
15: 97,874,030 (GRCm39) |
Y1384C |
unknown |
Het |
| Col6a3 |
T |
A |
1: 90,731,940 (GRCm39) |
I831F |
probably damaging |
Het |
| Cp |
G |
A |
3: 20,027,961 (GRCm39) |
V456I |
probably damaging |
Het |
| Cspp1 |
T |
A |
1: 10,196,688 (GRCm39) |
N900K |
probably damaging |
Het |
| Ctbp2 |
T |
C |
7: 132,615,967 (GRCm39) |
I323V |
probably benign |
Het |
| Ctnna2 |
C |
T |
6: 77,630,094 (GRCm39) |
R120H |
probably damaging |
Het |
| Cyp2a12 |
A |
G |
7: 26,733,575 (GRCm39) |
H318R |
probably benign |
Het |
| Cyp2c66 |
A |
T |
19: 39,151,766 (GRCm39) |
|
probably null |
Het |
| Cyp2j8 |
T |
C |
4: 96,395,614 (GRCm39) |
T4A |
probably benign |
Het |
| Cyp4v3 |
A |
G |
8: 45,773,674 (GRCm39) |
V165A |
possibly damaging |
Het |
| D5Ertd579e |
G |
A |
5: 36,773,571 (GRCm39) |
R275* |
probably null |
Het |
| Deup1 |
G |
T |
9: 15,512,264 (GRCm39) |
Q160K |
possibly damaging |
Het |
| Dhx36 |
A |
T |
3: 62,404,280 (GRCm39) |
I221K |
probably damaging |
Het |
| Dnah7b |
T |
A |
1: 46,272,886 (GRCm39) |
M2338K |
probably benign |
Het |
| Dync2li1 |
T |
G |
17: 84,940,969 (GRCm39) |
L62V |
probably benign |
Het |
| Ephb3 |
A |
G |
16: 21,039,245 (GRCm39) |
K367R |
probably benign |
Het |
| Etv3 |
A |
G |
3: 87,435,368 (GRCm39) |
K80E |
probably damaging |
Het |
| Flacc1 |
T |
A |
1: 58,706,965 (GRCm39) |
E234V |
probably damaging |
Het |
| Gdap1l1 |
T |
C |
2: 163,295,779 (GRCm39) |
F346L |
probably benign |
Het |
| Gm4787 |
C |
T |
12: 81,426,090 (GRCm39) |
V23M |
probably damaging |
Het |
| Greb1l |
T |
A |
18: 10,547,306 (GRCm39) |
I1508N |
probably damaging |
Het |
| Heatr5b |
G |
A |
17: 79,139,013 (GRCm39) |
T43I |
probably benign |
Het |
| Hephl1 |
T |
C |
9: 14,997,586 (GRCm39) |
Y360C |
probably damaging |
Het |
| Itgam |
A |
C |
7: 127,715,012 (GRCm39) |
T865P |
possibly damaging |
Het |
| Kcnma1 |
T |
C |
14: 24,054,186 (GRCm39) |
|
probably benign |
Het |
| Kidins220 |
T |
A |
12: 25,042,259 (GRCm39) |
C185* |
probably null |
Het |
| Klhl35 |
G |
T |
7: 99,118,275 (GRCm39) |
G273V |
probably damaging |
Het |
| Lama5 |
A |
G |
2: 179,850,045 (GRCm39) |
|
probably null |
Het |
| Lamc3 |
A |
G |
2: 31,805,966 (GRCm39) |
Q689R |
probably benign |
Het |
| Lnx2 |
C |
T |
5: 146,955,850 (GRCm39) |
V649I |
probably benign |
Het |
| Lrrc43 |
A |
G |
5: 123,637,675 (GRCm39) |
I281V |
probably benign |
Het |
| Ly6g6d |
C |
A |
17: 35,290,730 (GRCm39) |
A67S |
probably benign |
Het |
| Map1b |
A |
G |
13: 99,568,720 (GRCm39) |
S1334P |
probably benign |
Het |
| Mast1 |
T |
A |
8: 85,644,500 (GRCm39) |
T810S |
probably benign |
Het |
| Matcap1 |
G |
T |
8: 106,009,843 (GRCm39) |
R369S |
probably damaging |
Het |
| Mbnl1 |
A |
G |
3: 60,503,117 (GRCm39) |
M1V |
probably null |
Het |
| Mc5r |
T |
G |
18: 68,471,890 (GRCm39) |
M83R |
possibly damaging |
Het |
| Mkln1 |
T |
C |
6: 31,435,941 (GRCm39) |
F300S |
probably damaging |
Het |
| Mrgpre |
A |
T |
7: 143,335,088 (GRCm39) |
C138* |
probably null |
Het |
| Mtarc2 |
T |
A |
1: 184,566,116 (GRCm39) |
M186L |
probably benign |
Het |
| Ncbp1 |
C |
T |
4: 46,165,273 (GRCm39) |
Q529* |
probably null |
Het |
| Nherf1 |
A |
G |
11: 115,067,289 (GRCm39) |
D180G |
probably benign |
Het |
| Nrcam |
A |
G |
12: 44,613,082 (GRCm39) |
D591G |
probably benign |
Het |
| Nrxn3 |
A |
T |
12: 88,761,971 (GRCm39) |
H6L |
possibly damaging |
Het |
| Nsmaf |
T |
A |
4: 6,423,342 (GRCm39) |
D342V |
probably damaging |
Het |
| Oip5 |
TGAGAAA |
T |
2: 119,448,342 (GRCm39) |
|
probably benign |
Het |
| Omt2a |
T |
A |
9: 78,220,305 (GRCm39) |
E31D |
possibly damaging |
Het |
| Or4f62 |
A |
G |
2: 111,986,697 (GRCm39) |
T134A |
probably benign |
Het |
| Or52n2b |
A |
G |
7: 104,565,915 (GRCm39) |
I196T |
probably benign |
Het |
| Or5ac20 |
A |
G |
16: 59,104,348 (GRCm39) |
S171P |
probably benign |
Het |
| Or6c88 |
A |
C |
10: 129,406,895 (GRCm39) |
I124L |
probably damaging |
Het |
| Or9a2 |
C |
A |
6: 41,749,003 (GRCm39) |
V77F |
probably damaging |
Het |
| Phyhipl |
A |
G |
10: 70,404,815 (GRCm39) |
V131A |
probably benign |
Het |
| Pik3r5 |
A |
G |
11: 68,384,464 (GRCm39) |
M619V |
probably benign |
Het |
| Pramel19 |
T |
C |
4: 101,798,661 (GRCm39) |
Y211H |
probably benign |
Het |
| Ptprg |
A |
T |
14: 12,237,837 (GRCm38) |
E1431D |
probably benign |
Het |
| Rnf20 |
A |
G |
4: 49,638,029 (GRCm39) |
T85A |
probably damaging |
Het |
| Rtn3 |
A |
T |
19: 7,433,886 (GRCm39) |
I683K |
probably damaging |
Het |
| Rwdd3 |
A |
G |
3: 120,952,470 (GRCm39) |
F174L |
probably damaging |
Het |
| Ryr1 |
T |
C |
7: 28,778,208 (GRCm39) |
Q2096R |
possibly damaging |
Het |
| Scrn1 |
T |
C |
6: 54,511,407 (GRCm39) |
D111G |
probably damaging |
Het |
| Sema3e |
A |
G |
5: 14,302,646 (GRCm39) |
R724G |
possibly damaging |
Het |
| She |
A |
G |
3: 89,741,544 (GRCm39) |
M232V |
possibly damaging |
Het |
| Skic3 |
T |
A |
13: 76,333,275 (GRCm39) |
V1508E |
possibly damaging |
Het |
| Slc25a54 |
A |
T |
3: 109,020,132 (GRCm39) |
N382I |
possibly damaging |
Het |
| Slc26a2 |
T |
C |
18: 61,331,875 (GRCm39) |
M519V |
probably damaging |
Het |
| Slc9a1 |
T |
A |
4: 133,097,967 (GRCm39) |
L38H |
probably damaging |
Het |
| Snap47 |
A |
T |
11: 59,319,369 (GRCm39) |
D256E |
probably damaging |
Het |
| Tacc3 |
A |
G |
5: 33,829,326 (GRCm39) |
T610A |
probably benign |
Het |
| Tbc1d30 |
G |
A |
10: 121,103,121 (GRCm39) |
T637M |
probably benign |
Het |
| Tbcd |
T |
A |
11: 121,464,681 (GRCm39) |
M572K |
probably benign |
Het |
| Thoc7 |
A |
T |
14: 13,953,460 (GRCm38) |
D68E |
probably benign |
Het |
| Tmpo |
G |
A |
10: 90,989,171 (GRCm39) |
T250M |
probably damaging |
Het |
| Tmtc1 |
TGTCCGCCAGGCCCTTGCCCCAGAAGTC |
TGTC |
6: 148,345,445 (GRCm39) |
|
probably benign |
Het |
| Tnfaip1 |
A |
T |
11: 78,418,396 (GRCm39) |
C224S |
possibly damaging |
Het |
| Tshz1 |
T |
C |
18: 84,032,987 (GRCm39) |
T474A |
probably benign |
Het |
| Tspoap1 |
C |
T |
11: 87,657,222 (GRCm39) |
Q345* |
probably null |
Het |
| Ttc21a |
A |
G |
9: 119,774,067 (GRCm39) |
E258G |
possibly damaging |
Het |
| Ttyh1 |
T |
C |
7: 4,131,225 (GRCm39) |
L232P |
probably damaging |
Het |
| Usp2 |
T |
A |
9: 43,987,110 (GRCm39) |
L136Q |
probably damaging |
Het |
| Usp31 |
T |
C |
7: 121,247,868 (GRCm39) |
S1192G |
probably damaging |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,768,738 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0254:Clip1
|
UTSW |
5 |
123,755,395 (GRCm39) |
splice site |
probably benign |
|
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,768,466 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,791,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,751,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAGCCATCGTTCTTCCCTATG -3'
(R):5'- ACAAGTCAACAAGTTCTGGTCTG -3'
Sequencing Primer
(F):5'- TGGGTTCATCTAAAACAATCCCAG -3'
(R):5'- CAGATCCCCTGGAAATGGACTTATG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation