Mutagenetix > Incidental Mutation

Incidental Mutation 'R4940:Ankrd11'

383012

Institutional Source

Beutler Lab

Gene Symbol

Ankrd11

Ensembl Gene

ENSMUSG00000035569

Gene Name

ankyrin repeat domain 11

Synonyms

Yod, 3010027A04Rik, 2410104C19Rik, 9530048I21Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R4940 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

123610561-123769016 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 123616560 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 2410 (Y2410H)

Ref Sequence

ENSEMBL: ENSMUSP00000095939 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000098333] [ENSMUST00000098334] [ENSMUST00000127664] [ENSMUST00000172906]

AlphaFold

E9Q4F7

Predicted Effect

probably damaging
Transcript: ENSMUST00000098333
AA Change: Y2431H

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000095938
Gene: ENSMUSG00000035569
AA Change: Y2431H

Domain	Start	End	E-Value	Type
ANK	188	217	2.58e-3	SMART
ANK	221	250	1.31e-4	SMART
ANK	254	283	5.04e-6	SMART
low complexity region	311	324	N/A	INTRINSIC
low complexity region	366	377	N/A	INTRINSIC
low complexity region	429	440	N/A	INTRINSIC
low complexity region	470	487	N/A	INTRINSIC
low complexity region	499	521	N/A	INTRINSIC
low complexity region	534	549	N/A	INTRINSIC
low complexity region	596	609	N/A	INTRINSIC
low complexity region	649	669	N/A	INTRINSIC
coiled coil region	786	826	N/A	INTRINSIC
low complexity region	867	877	N/A	INTRINSIC
low complexity region	965	984	N/A	INTRINSIC
low complexity region	1040	1055	N/A	INTRINSIC
low complexity region	1058	1082	N/A	INTRINSIC
low complexity region	1187	1200	N/A	INTRINSIC
low complexity region	1204	1227	N/A	INTRINSIC
low complexity region	1268	1289	N/A	INTRINSIC
low complexity region	1294	1306	N/A	INTRINSIC
coiled coil region	1374	1406	N/A	INTRINSIC
low complexity region	1476	1496	N/A	INTRINSIC
low complexity region	1508	1523	N/A	INTRINSIC
low complexity region	1526	1547	N/A	INTRINSIC
coiled coil region	1598	1625	N/A	INTRINSIC
low complexity region	1770	1781	N/A	INTRINSIC
low complexity region	1874	1885	N/A	INTRINSIC
low complexity region	1913	1922	N/A	INTRINSIC
low complexity region	1969	1979	N/A	INTRINSIC
low complexity region	2035	2045	N/A	INTRINSIC
low complexity region	2057	2071	N/A	INTRINSIC
low complexity region	2162	2179	N/A	INTRINSIC
low complexity region	2191	2209	N/A	INTRINSIC
low complexity region	2224	2236	N/A	INTRINSIC
low complexity region	2250	2263	N/A	INTRINSIC
low complexity region	2294	2305	N/A	INTRINSIC
low complexity region	2391	2409	N/A	INTRINSIC
low complexity region	2445	2455	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000098334
AA Change: Y2410H

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000095939
Gene: ENSMUSG00000035569
AA Change: Y2410H

Domain	Start	End	E-Value	Type
ANK	167	196	2.58e-3	SMART
ANK	200	229	1.31e-4	SMART
ANK	233	262	5.04e-6	SMART
low complexity region	290	303	N/A	INTRINSIC
low complexity region	345	356	N/A	INTRINSIC
low complexity region	408	419	N/A	INTRINSIC
low complexity region	449	466	N/A	INTRINSIC
low complexity region	478	500	N/A	INTRINSIC
low complexity region	513	528	N/A	INTRINSIC
low complexity region	575	588	N/A	INTRINSIC
low complexity region	628	648	N/A	INTRINSIC
coiled coil region	765	805	N/A	INTRINSIC
low complexity region	846	856	N/A	INTRINSIC
low complexity region	944	963	N/A	INTRINSIC
low complexity region	1019	1034	N/A	INTRINSIC
low complexity region	1037	1061	N/A	INTRINSIC
low complexity region	1166	1179	N/A	INTRINSIC
low complexity region	1183	1206	N/A	INTRINSIC
low complexity region	1247	1268	N/A	INTRINSIC
low complexity region	1273	1285	N/A	INTRINSIC
coiled coil region	1353	1385	N/A	INTRINSIC
low complexity region	1455	1475	N/A	INTRINSIC
low complexity region	1487	1502	N/A	INTRINSIC
low complexity region	1505	1526	N/A	INTRINSIC
coiled coil region	1577	1604	N/A	INTRINSIC
low complexity region	1749	1760	N/A	INTRINSIC
low complexity region	1853	1864	N/A	INTRINSIC
low complexity region	1892	1901	N/A	INTRINSIC
low complexity region	1948	1958	N/A	INTRINSIC
low complexity region	2014	2024	N/A	INTRINSIC
low complexity region	2036	2050	N/A	INTRINSIC
low complexity region	2141	2158	N/A	INTRINSIC
low complexity region	2170	2188	N/A	INTRINSIC
low complexity region	2203	2215	N/A	INTRINSIC
low complexity region	2229	2242	N/A	INTRINSIC
low complexity region	2273	2284	N/A	INTRINSIC
low complexity region	2370	2388	N/A	INTRINSIC
low complexity region	2424	2434	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000127664

SMART Domains

Protein: ENSMUSP00000118564
Gene: ENSMUSG00000092329

Domain	Start	End	E-Value	Type
Pfam:Glycos_transf_2	104	287	7.4e-31	PFAM
Pfam:Glyco_transf_7C	261	331	4.9e-8	PFAM
RICIN	406	531	9.28e-27	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000172906

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211940

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000212728

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.5%
20x: 93.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
PHENOTYPE: Mice homozygous for a spontaneous allele die by E9.5, are small and fail to turn. Mice heterozygous for a spontaneous allele exhibit craniofacial abnormalities, decreased weight, osteoporosis and osteopenia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4931414P19Rik	T	C	14: 54,828,782 (GRCm39)	T240A	probably benign	Het
Abca15	T	C	7: 119,931,917 (GRCm39)	Y57H	probably benign	Het
Adgrf4	A	G	17: 42,977,420 (GRCm39)	I641T	possibly damaging	Het
Apbb2	C	A	5: 66,609,604 (GRCm39)	L14F	probably null	Het
Arhgdia	T	C	11: 120,470,061 (GRCm39)	D204G	probably damaging	Het
Armh4	A	T	14: 50,010,939 (GRCm39)	M256K	probably benign	Het
Catsperd	A	T	17: 56,969,736 (GRCm39)	Y610F	possibly damaging	Het
Cblb	T	A	16: 51,853,466 (GRCm39)	D27E	probably damaging	Het
Ccdc180	A	T	4: 45,917,453 (GRCm39)	I893F	probably damaging	Het
Ccdc180	A	G	4: 45,917,508 (GRCm39)	H911R	probably damaging	Het
Cdh23	T	A	10: 60,143,714 (GRCm39)	I2966F	probably damaging	Het
Cfap299	A	G	5: 98,885,495 (GRCm39)	H134R	possibly damaging	Het
Chat	G	A	14: 32,141,062 (GRCm39)	P445L	probably damaging	Het
Chdh	G	T	14: 29,754,809 (GRCm39)	R273L	possibly damaging	Het
Clic3	T	C	2: 25,347,929 (GRCm39)	V72A	probably benign	Het
Cyp2d12	T	A	15: 82,442,251 (GRCm39)	D244E	probably benign	Het
Ddr1	T	A	17: 36,001,022 (GRCm39)	D241V	probably damaging	Het
Dock7	T	A	4: 98,908,314 (GRCm39)	K605N	probably damaging	Het
Dsg2	T	A	18: 20,712,487 (GRCm39)	F164I	probably damaging	Het
Dstyk	T	A	1: 132,380,844 (GRCm39)	N446K	probably damaging	Het
Epb42	A	T	2: 120,864,932 (GRCm39)	L53Q	probably damaging	Het
Extl2	G	C	3: 115,820,841 (GRCm39)	K229N	probably benign	Het
Frmd4b	T	A	6: 97,275,051 (GRCm39)	S617C	probably damaging	Het
Fscb	C	T	12: 64,520,588 (GRCm39)	V293I	probably benign	Het
Glp2r	G	T	11: 67,648,419 (GRCm39)	Y94*	probably null	Het
Gm4978	A	C	9: 69,358,154 (GRCm39)		probably benign	Het
Gm6729	A	G	10: 86,376,252 (GRCm39)		noncoding transcript	Het
Gnat2	A	C	3: 108,007,932 (GRCm39)	N293T	probably benign	Het
Herpud1	T	C	8: 95,117,470 (GRCm39)	I142T	probably benign	Het
Irak2	G	A	6: 113,670,691 (GRCm39)	V536I	probably benign	Het
Kcnu1	A	T	8: 26,387,890 (GRCm39)		probably null	Het
Kdm4a	A	G	4: 118,018,951 (GRCm39)	S422P	probably benign	Het
Lair1	T	A	7: 4,031,948 (GRCm39)	D53V	probably benign	Het
Lhx1	G	T	11: 84,410,735 (GRCm39)	Y196*	probably null	Het
Lrrc37a	G	A	11: 103,388,438 (GRCm39)	T2329I	unknown	Het
Mag	T	C	7: 30,608,625 (GRCm39)	D163G	probably damaging	Het
Magi3	A	G	3: 103,958,708 (GRCm39)	V459A	probably damaging	Het
Med13	A	G	11: 86,178,944 (GRCm39)	Y1451H	probably damaging	Het
Megf8	T	A	7: 25,060,131 (GRCm39)	C2341S	probably damaging	Het
Mppe1	A	G	18: 67,361,095 (GRCm39)	C221R	probably damaging	Het
Mtus1	T	A	8: 41,494,515 (GRCm39)	H39L	possibly damaging	Het
Nkpd1	C	T	7: 19,257,498 (GRCm39)	Q276*	probably null	Het
Nkx3-1	G	A	14: 69,428,367 (GRCm39)	G72S	probably benign	Het
Nutm2	T	C	13: 50,628,909 (GRCm39)	C658R	possibly damaging	Het
Olfm1	T	C	2: 28,112,602 (GRCm39)	V239A	possibly damaging	Het
Pcnx1	C	T	12: 81,964,567 (GRCm39)	H245Y	possibly damaging	Het
Pgm3	A	G	9: 86,441,529 (GRCm39)	L356S	probably damaging	Het
Pik3r4	C	G	9: 105,546,193 (GRCm39)	H207D	probably benign	Het
Pkd1l1	T	C	11: 8,794,585 (GRCm39)	T1859A	probably benign	Het
Pon3	A	T	6: 5,221,625 (GRCm39)	V335E	possibly damaging	Het
Ppp4r3b	A	G	11: 29,161,740 (GRCm39)	T705A	probably benign	Het
Prmt7	T	C	8: 106,963,910 (GRCm39)	V268A	probably benign	Het
Psd	C	T	19: 46,310,856 (GRCm39)	G398R	probably damaging	Het
Pygl	A	G	12: 70,253,155 (GRCm39)	V188A	probably damaging	Het
Rnf13	T	A	3: 57,703,627 (GRCm39)	N110K	probably damaging	Het
Rnf170	C	T	8: 26,615,939 (GRCm39)	Q77*	probably null	Het
Rrp8	A	T	7: 105,383,284 (GRCm39)	Y327*	probably null	Het
Ruvbl2	T	C	7: 45,074,150 (GRCm39)	D228G	probably damaging	Het
Scgn	T	A	13: 24,173,807 (GRCm39)	T35S	probably benign	Het
Scyl3	C	T	1: 163,762,316 (GRCm39)	P74S	probably damaging	Het
Sec61b	T	G	4: 47,483,074 (GRCm39)	S123A	probably benign	Het
Sertad2	T	C	11: 20,597,899 (GRCm39)	S32P	possibly damaging	Het
Slc23a3	T	C	1: 75,110,447 (GRCm39)		probably null	Het
Sult2a2	T	G	7: 13,472,223 (GRCm39)	V140G	probably benign	Het
Tbc1d4	A	T	14: 101,744,667 (GRCm39)	S320T	probably benign	Het
Trabd2b	T	C	4: 114,266,141 (GRCm39)	Y52H	probably damaging	Het
Traf2	T	C	2: 25,420,300 (GRCm39)	E183G	probably null	Het
Trip10	G	T	17: 57,570,017 (GRCm39)	V561F	possibly damaging	Het
Ttc7	G	T	17: 87,614,386 (GRCm39)	V184F	probably benign	Het
Ubc	A	G	5: 125,463,293 (GRCm39)	V678A	probably benign	Het
Unk	A	G	11: 115,944,491 (GRCm39)	E414G	possibly damaging	Het
Usp42	T	C	5: 143,705,517 (GRCm39)	N365D	probably damaging	Het
Zbtb26	A	T	2: 37,326,781 (GRCm39)	I85K	probably damaging	Het
Zfhx2	A	T	14: 55,303,891 (GRCm39)	H1364Q	possibly damaging	Het

Other mutations in Ankrd11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00949:Ankrd11	APN	8	123,635,467 (GRCm39)	missense	possibly damaging	0.59
IGL00971:Ankrd11	APN	8	123,622,092 (GRCm39)	missense	probably damaging	1.00
IGL01017:Ankrd11	APN	8	123,621,467 (GRCm39)	missense	probably damaging	1.00
IGL01137:Ankrd11	APN	8	123,611,075 (GRCm39)	missense	probably damaging	0.99
IGL01659:Ankrd11	APN	8	123,622,110 (GRCm39)	missense	probably damaging	1.00
IGL01920:Ankrd11	APN	8	123,642,636 (GRCm39)	splice site	probably benign
IGL01964:Ankrd11	APN	8	123,616,475 (GRCm39)	missense	probably damaging	0.97
IGL02131:Ankrd11	APN	8	123,621,149 (GRCm39)	missense	probably damaging	1.00
IGL02226:Ankrd11	APN	8	123,618,984 (GRCm39)	missense	probably damaging	1.00
IGL02549:Ankrd11	APN	8	123,618,032 (GRCm39)	missense	probably damaging	1.00
IGL02642:Ankrd11	APN	8	123,617,390 (GRCm39)	missense	probably damaging	1.00
IGL02643:Ankrd11	APN	8	123,619,061 (GRCm39)	missense	probably damaging	0.98
IGL02861:Ankrd11	APN	8	123,622,566 (GRCm39)	missense	probably damaging	0.99
IGL03086:Ankrd11	APN	8	123,621,249 (GRCm39)	missense	probably damaging	1.00
IGL03336:Ankrd11	APN	8	123,618,582 (GRCm39)	missense	probably benign	0.00
anchors	UTSW	8	123,622,509 (GRCm39)	missense	probably damaging	0.99
away	UTSW	8	123,618,692 (GRCm39)	missense	probably damaging	1.00
bluebell	UTSW	8	123,618,524 (GRCm39)	missense	probably damaging	0.97
Navy	UTSW	8	123,635,473 (GRCm39)	nonsense	probably null
BB001:Ankrd11	UTSW	8	123,622,641 (GRCm39)	missense	possibly damaging	0.95
BB011:Ankrd11	UTSW	8	123,622,641 (GRCm39)	missense	possibly damaging	0.95
R0051:Ankrd11	UTSW	8	123,616,481 (GRCm39)	missense	probably damaging	1.00
R0051:Ankrd11	UTSW	8	123,616,481 (GRCm39)	missense	probably damaging	1.00
R0110:Ankrd11	UTSW	8	123,618,914 (GRCm39)	missense	possibly damaging	0.95
R0281:Ankrd11	UTSW	8	123,622,307 (GRCm39)	missense	probably benign	0.01
R0450:Ankrd11	UTSW	8	123,618,914 (GRCm39)	missense	possibly damaging	0.95
R0481:Ankrd11	UTSW	8	123,626,775 (GRCm39)	missense	probably damaging	1.00
R0542:Ankrd11	UTSW	8	123,622,509 (GRCm39)	missense	probably damaging	0.99
R0606:Ankrd11	UTSW	8	123,619,571 (GRCm39)	missense	probably benign	0.04
R0702:Ankrd11	UTSW	8	123,616,505 (GRCm39)	missense	probably damaging	1.00
R0730:Ankrd11	UTSW	8	123,618,692 (GRCm39)	missense	probably damaging	1.00
R0737:Ankrd11	UTSW	8	123,622,575 (GRCm39)	missense	probably damaging	0.99
R1401:Ankrd11	UTSW	8	123,619,789 (GRCm39)	missense	probably benign	0.23
R1464:Ankrd11	UTSW	8	123,619,463 (GRCm39)	missense	probably damaging	1.00
R1464:Ankrd11	UTSW	8	123,619,463 (GRCm39)	missense	probably damaging	1.00
R1470:Ankrd11	UTSW	8	123,626,463 (GRCm39)	missense	probably damaging	0.98
R1470:Ankrd11	UTSW	8	123,626,463 (GRCm39)	missense	probably damaging	0.98
R1641:Ankrd11	UTSW	8	123,618,485 (GRCm39)	missense	probably benign	0.03
R1950:Ankrd11	UTSW	8	123,616,608 (GRCm39)	missense	probably damaging	1.00
R2004:Ankrd11	UTSW	8	123,629,161 (GRCm39)	critical splice donor site	probably null
R2401:Ankrd11	UTSW	8	123,635,473 (GRCm39)	nonsense	probably null
R2425:Ankrd11	UTSW	8	123,619,902 (GRCm39)	missense	possibly damaging	0.86
R2830:Ankrd11	UTSW	8	123,618,935 (GRCm39)	missense	probably damaging	1.00
R2910:Ankrd11	UTSW	8	123,635,537 (GRCm39)	missense	probably damaging	1.00
R2911:Ankrd11	UTSW	8	123,635,537 (GRCm39)	missense	probably damaging	1.00
R3736:Ankrd11	UTSW	8	123,618,524 (GRCm39)	missense	probably damaging	0.97
R3738:Ankrd11	UTSW	8	123,623,454 (GRCm39)	unclassified	probably benign
R3739:Ankrd11	UTSW	8	123,623,454 (GRCm39)	unclassified	probably benign
R3813:Ankrd11	UTSW	8	123,618,117 (GRCm39)	missense	probably benign
R4012:Ankrd11	UTSW	8	123,619,156 (GRCm39)	missense	probably damaging	0.98
R4183:Ankrd11	UTSW	8	123,626,415 (GRCm39)	missense	possibly damaging	0.88
R4213:Ankrd11	UTSW	8	123,617,765 (GRCm39)	missense	probably benign	0.00
R4469:Ankrd11	UTSW	8	123,623,326 (GRCm39)	missense	probably damaging	1.00
R4482:Ankrd11	UTSW	8	123,620,228 (GRCm39)	missense	probably damaging	1.00
R4935:Ankrd11	UTSW	8	123,626,922 (GRCm39)	missense	probably benign	0.02
R5145:Ankrd11	UTSW	8	123,617,943 (GRCm39)	utr 3 prime	probably benign
R5154:Ankrd11	UTSW	8	123,619,878 (GRCm39)	missense	probably damaging	1.00
R5230:Ankrd11	UTSW	8	123,617,216 (GRCm39)	missense	probably benign	0.11
R5283:Ankrd11	UTSW	8	123,610,921 (GRCm39)	missense	probably damaging	1.00
R5377:Ankrd11	UTSW	8	123,620,453 (GRCm39)	splice site	probably null
R5513:Ankrd11	UTSW	8	123,619,259 (GRCm39)	missense	probably benign	0.38
R5518:Ankrd11	UTSW	8	123,617,733 (GRCm39)	missense	possibly damaging	0.93
R5549:Ankrd11	UTSW	8	123,617,117 (GRCm39)	missense	probably benign	0.02
R5579:Ankrd11	UTSW	8	123,610,970 (GRCm39)	missense	probably damaging	0.97
R5595:Ankrd11	UTSW	8	123,621,043 (GRCm39)	nonsense	probably null
R5650:Ankrd11	UTSW	8	123,614,136 (GRCm39)	missense	probably damaging	0.99
R5717:Ankrd11	UTSW	8	123,619,377 (GRCm39)	missense	possibly damaging	0.92
R5753:Ankrd11	UTSW	8	123,622,043 (GRCm39)	missense	possibly damaging	0.90
R5782:Ankrd11	UTSW	8	123,626,756 (GRCm39)	missense	probably damaging	1.00
R5812:Ankrd11	UTSW	8	123,620,544 (GRCm39)	splice site	probably null
R5823:Ankrd11	UTSW	8	123,622,529 (GRCm39)	missense	probably benign	0.12
R5900:Ankrd11	UTSW	8	123,617,805 (GRCm39)	missense	probably benign	0.00
R5975:Ankrd11	UTSW	8	123,616,488 (GRCm39)	missense	possibly damaging	0.93
R5979:Ankrd11	UTSW	8	123,619,139 (GRCm39)	missense	probably damaging	1.00
R6000:Ankrd11	UTSW	8	123,617,934 (GRCm39)	missense	possibly damaging	0.73
R6145:Ankrd11	UTSW	8	123,619,400 (GRCm39)	missense	probably damaging	1.00
R6252:Ankrd11	UTSW	8	123,620,561 (GRCm39)	missense	possibly damaging	0.87
R6302:Ankrd11	UTSW	8	123,616,728 (GRCm39)	missense	probably benign
R6457:Ankrd11	UTSW	8	123,635,503 (GRCm39)	missense	probably damaging	1.00
R6513:Ankrd11	UTSW	8	123,616,919 (GRCm39)	missense	probably benign	0.02
R6582:Ankrd11	UTSW	8	123,618,368 (GRCm39)	missense	probably benign	0.00
R6738:Ankrd11	UTSW	8	123,618,660 (GRCm39)	missense	probably damaging	0.99
R6865:Ankrd11	UTSW	8	123,621,683 (GRCm39)	missense	probably benign	0.41
R6913:Ankrd11	UTSW	8	123,621,650 (GRCm39)	missense	probably benign	0.01
R7101:Ankrd11	UTSW	8	123,622,194 (GRCm39)	missense	probably benign	0.35
R7116:Ankrd11	UTSW	8	123,622,869 (GRCm39)	missense	probably damaging	1.00
R7477:Ankrd11	UTSW	8	123,621,124 (GRCm39)	missense	possibly damaging	0.91
R7534:Ankrd11	UTSW	8	123,621,149 (GRCm39)	missense	probably damaging	1.00
R7555:Ankrd11	UTSW	8	123,614,145 (GRCm39)	missense	probably damaging	0.99
R7627:Ankrd11	UTSW	8	123,617,690 (GRCm39)	missense	possibly damaging	0.63
R7658:Ankrd11	UTSW	8	123,620,403 (GRCm39)	missense	probably benign
R7721:Ankrd11	UTSW	8	123,621,498 (GRCm39)	missense	probably damaging	1.00
R7731:Ankrd11	UTSW	8	123,622,172 (GRCm39)	missense	probably benign	0.12
R7792:Ankrd11	UTSW	8	123,610,970 (GRCm39)	missense	probably damaging	0.97
R7924:Ankrd11	UTSW	8	123,622,641 (GRCm39)	missense	possibly damaging	0.95
R7939:Ankrd11	UTSW	8	123,617,812 (GRCm39)	missense	probably damaging	1.00
R8022:Ankrd11	UTSW	8	123,614,332 (GRCm39)	missense	probably damaging	1.00
R8222:Ankrd11	UTSW	8	123,622,347 (GRCm39)	missense	probably damaging	0.98
R8362:Ankrd11	UTSW	8	123,618,797 (GRCm39)	missense	probably damaging	0.96
R8430:Ankrd11	UTSW	8	123,620,105 (GRCm39)	missense	probably benign	0.01
R8511:Ankrd11	UTSW	8	123,626,468 (GRCm39)	missense
R8726:Ankrd11	UTSW	8	123,620,765 (GRCm39)	missense	possibly damaging	0.90
R8888:Ankrd11	UTSW	8	123,621,014 (GRCm39)	missense	possibly damaging	0.87
R8895:Ankrd11	UTSW	8	123,621,014 (GRCm39)	missense	possibly damaging	0.87
R8928:Ankrd11	UTSW	8	123,622,718 (GRCm39)	missense	probably damaging	0.99
R8930:Ankrd11	UTSW	8	123,622,718 (GRCm39)	missense	probably damaging	0.99
R8931:Ankrd11	UTSW	8	123,622,718 (GRCm39)	missense	probably damaging	0.99
R8936:Ankrd11	UTSW	8	123,621,840 (GRCm39)	missense	possibly damaging	0.69
R9018:Ankrd11	UTSW	8	123,622,251 (GRCm39)	missense	probably damaging	1.00
R9113:Ankrd11	UTSW	8	123,614,072 (GRCm39)	missense	possibly damaging	0.60
R9399:Ankrd11	UTSW	8	123,618,179 (GRCm39)	missense	probably benign
R9644:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
R9645:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
R9647:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
R9683:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
RF019:Ankrd11	UTSW	8	123,623,373 (GRCm39)	missense	probably damaging	1.00
Z1176:Ankrd11	UTSW	8	123,622,542 (GRCm39)	missense	possibly damaging	0.68
Z1177:Ankrd11	UTSW	8	123,626,881 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AATGTCACTGCCTCCTGAC -3'
(R):5'- TACCTGCAGCAGAGAAGGAC -3'

Sequencing Primer
(F):5'- CTTGTGGAGACAGAGCCCATG -3'
(R):5'- AGCCTCTAGAGCCAAGGGTC -3'

Posted On

2016-04-27