|Institutional Source||Beutler Lab|
|Gene Name||aldehyde dehydrogenase 3 family, member B1|
|Synonyms||1700001N19Rik, ALDH7, ALDH4|
|Is this an essential gene?||Probably non essential (E-score: 0.068)|
|Stock #||R0320 (G1)|
|Chromosomal Location||3913493-3929761 bp(-) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||T to C at 3918999 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000056276 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000051803]|
|Predicted Effect||probably benign
|Coding Region Coverage||
|Validation Efficiency||100% (71/71)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Aldh3b1||
(F):5'- TTAAAGTAGCGGAACCAGGCCAC -3'
(R):5'- TTCCTGACCATCAGTCAGCGAAAC -3'
(F):5'- TCCACATAGCAGGGGTTCTT -3'
(R):5'- AAACTGGCTCTGGCCTTAG -3'