Mutagenetix > Incidental Mutation

Incidental Mutation 'R0347:Dnah7b'

38420

Institutional Source

Beutler Lab

Gene Symbol

Dnah7b

Ensembl Gene

ENSMUSG00000041144

Gene Name

dynein, axonemal, heavy chain 7B

Synonyms

Dnahc7b, LOC227058

MMRRC Submission

038554-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.118) question?

Stock #

R0347 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

46066315-46373546 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 46240944 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 2678 (S2678T)

Ref Sequence

ENSEMBL: ENSMUSP00000068738 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000069293]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000069293
AA Change: S2678T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000068738
Gene: ENSMUSG00000041144
AA Change: S2678T

Domain	Start	End	E-Value	Type
coiled coil region	760	790	N/A	INTRINSIC
Pfam:DHC_N2	800	1209	3.7e-150	PFAM
AAA	1364	1503	3.24e-1	SMART
AAA	2012	2160	5.39e-2	SMART
Pfam:AAA_8	2347	2618	2.4e-75	PFAM
Pfam:MT	2630	2979	2.6e-54	PFAM
Pfam:AAA_9	3001	3226	2.3e-98	PFAM
Pfam:Dynein_heavy	3362	4064	8.4e-288	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000187548

Meta Mutation Damage Score

0.0773

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.2%
20x: 91.8%

Validation Efficiency

100% (78/78)

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810043G02Rik	A	T	10: 77,984,422 (GRCm38)	I209F	probably damaging	Het
5830411N06Rik	T	A	7: 140,297,854 (GRCm38)	H800Q	probably damaging	Het
Abca4	A	G	3: 122,120,099 (GRCm38)	E908G	probably benign	Het
Abcb5	T	A	12: 118,965,251 (GRCm38)		probably benign	Het
Adhfe1	T	A	1: 9,553,430 (GRCm38)	F102Y	probably benign	Het
Aff4	A	G	11: 53,400,088 (GRCm38)	Y625C	probably benign	Het
Alox5	T	C	6: 116,413,552 (GRCm38)	E488G	possibly damaging	Het
Ankmy2	T	C	12: 36,193,754 (GRCm38)	C323R	probably damaging	Het
Ankrd28	A	G	14: 31,702,022 (GRCm38)	*1084R	probably null	Het
Apol10a	A	T	15: 77,488,691 (GRCm38)	I176F	probably damaging	Het
Arhgap26	C	T	18: 38,617,744 (GRCm38)	T70I	unknown	Het
Arid2	A	G	15: 96,370,952 (GRCm38)	N982S	probably benign	Het
Bcl2	G	A	1: 106,712,562 (GRCm38)	R107C	probably damaging	Het
Camsap3	A	G	8: 3,602,029 (GRCm38)	D291G	probably damaging	Het
Camta1	C	A	4: 151,075,140 (GRCm38)	R1614L	probably damaging	Het
Cdc20b	G	T	13: 113,059,827 (GRCm38)	G162V	probably damaging	Het
Cep44	T	G	8: 56,545,475 (GRCm38)	E56A	probably damaging	Het
Cfap65	A	G	1: 74,926,444 (GRCm38)	L469P	probably damaging	Het
Cilp	T	A	9: 65,280,153 (GRCm38)	C1177S	probably benign	Het
Ctnnbip1	C	T	4: 149,545,754 (GRCm38)	P7S	probably damaging	Het
Cyp11a1	T	C	9: 58,016,260 (GRCm38)		probably benign	Het
Cyp3a11	C	T	5: 145,865,925 (GRCm38)	V253M	possibly damaging	Het
D630045J12Rik	C	A	6: 38,181,392 (GRCm38)	V1117L	probably damaging	Het
Dock1	T	C	7: 134,763,867 (GRCm38)	I428T	probably damaging	Het
Fam83f	A	G	15: 80,672,257 (GRCm38)	D114G	probably damaging	Het
Flt3	T	A	5: 147,357,992 (GRCm38)	N423I	probably damaging	Het
Fnbp1l	A	T	3: 122,590,175 (GRCm38)	F31L	probably damaging	Het
Glrx3	G	A	7: 137,437,701 (GRCm38)	E10K	unknown	Het
Gm12185	T	C	11: 48,915,182 (GRCm38)	E394G	probably benign	Het
Gm15448	A	T	7: 3,822,874 (GRCm38)	V332E	probably damaging	Het
Gpatch1	C	T	7: 35,297,631 (GRCm38)	V381M	probably benign	Het
Grm8	T	C	6: 27,981,222 (GRCm38)	S230G	probably benign	Het
Heyl	A	T	4: 123,233,940 (GRCm38)	D25V	probably benign	Het
Junb	G	A	8: 84,978,478 (GRCm38)		probably benign	Het
Klhl29	C	A	12: 5,084,354 (GRCm38)	V747F	probably damaging	Het
Krt77	T	C	15: 101,859,869 (GRCm38)	H569R	unknown	Het
Ldhb	T	C	6: 142,494,133 (GRCm38)	N227S	probably benign	Het
Megf6	A	G	4: 154,254,635 (GRCm38)	D543G	possibly damaging	Het
Mrps23	A	T	11: 88,210,693 (GRCm38)	Q136L	probably benign	Het
Myh2	C	T	11: 67,185,304 (GRCm38)		probably benign	Het
Nadk2	T	A	15: 9,084,207 (GRCm38)	D133E	probably benign	Het
Neurod4	G	A	10: 130,271,111 (GRCm38)	T98I	probably damaging	Het
Nfatc2	G	T	2: 168,536,290 (GRCm38)	T465K	probably damaging	Het
Nipbl	A	G	15: 8,350,732 (GRCm38)	S859P	probably benign	Het
Nipsnap3a	T	C	4: 52,997,155 (GRCm38)		probably benign	Het
Nlrp4c	A	G	7: 6,066,416 (GRCm38)	K439E	possibly damaging	Het
Olfr1419	A	T	19: 11,870,433 (GRCm38)	L261H	probably damaging	Het
Olfr392	C	T	11: 73,814,311 (GRCm38)	G257D	probably damaging	Het
Olfr434	T	C	6: 43,217,362 (GRCm38)	F150L	probably benign	Het
Pds5b	T	A	5: 150,736,427 (GRCm38)		probably benign	Het
Plch1	A	G	3: 63,753,316 (GRCm38)	M282T	probably damaging	Het
Plch2	C	A	4: 154,986,721 (GRCm38)	R1067L	possibly damaging	Het
Pou2f2	A	C	7: 25,097,701 (GRCm38)	F206V	probably damaging	Het
Prss50	A	G	9: 110,862,350 (GRCm38)	I49V	probably damaging	Het
Rexo5	T	A	7: 119,823,896 (GRCm38)		probably null	Het
Rgl2	C	T	17: 33,932,738 (GRCm38)	T252I	probably damaging	Het
Rp1l1	A	T	14: 64,030,804 (GRCm38)	K1280*	probably null	Het
Rpl24	T	A	16: 55,970,177 (GRCm38)		probably null	Het
Satb1	T	A	17: 51,739,906 (GRCm38)	K763*	probably null	Het
Sema6a	T	A	18: 47,291,129 (GRCm38)	R237S	probably damaging	Het
Spg11	T	C	2: 122,097,369 (GRCm38)	T645A	probably damaging	Het
Srrt	T	A	5: 137,299,676 (GRCm38)		probably benign	Het
Tanc1	T	C	2: 59,842,991 (GRCm38)	V1480A	probably benign	Het
Tbc1d2	T	C	4: 46,620,574 (GRCm38)	D412G	possibly damaging	Het
Tecrl	T	C	5: 83,294,632 (GRCm38)	E198G	probably damaging	Het
Tigd4	A	G	3: 84,593,860 (GRCm38)	D28G	probably damaging	Het
Trp53bp2	T	G	1: 182,441,648 (GRCm38)	L226V	probably benign	Het
Ttll13	T	C	7: 80,260,505 (GRCm38)	S799P	possibly damaging	Het
Vps13c	A	T	9: 67,910,233 (GRCm38)	Q1062H	possibly damaging	Het
Wnt10a	T	G	1: 74,793,543 (GRCm38)	H98Q	probably damaging	Het
Zfp651	C	T	9: 121,763,102 (GRCm38)	P198S	probably damaging	Het
Zfp959	T	A	17: 55,897,180 (GRCm38)	Y69*	probably null	Het
Znrd1as	T	A	17: 36,965,315 (GRCm38)	M114K	probably damaging	Het

Other mutations in Dnah7b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00336:Dnah7b	APN	1	46,142,149 (GRCm38)	missense	probably benign	0.04
IGL00796:Dnah7b	APN	1	46,211,337 (GRCm38)	missense	probably damaging	0.96
IGL00825:Dnah7b	APN	1	46,224,651 (GRCm38)	missense	probably damaging	1.00
IGL00910:Dnah7b	APN	1	46,066,729 (GRCm38)	unclassified	probably benign
IGL00950:Dnah7b	APN	1	46,214,322 (GRCm38)	missense	probably benign	0.07
IGL01142:Dnah7b	APN	1	46,195,378 (GRCm38)	critical splice donor site	probably null
IGL01350:Dnah7b	APN	1	46,081,432 (GRCm38)	splice site	probably benign
IGL01392:Dnah7b	APN	1	46,126,788 (GRCm38)	missense	probably damaging	1.00
IGL01403:Dnah7b	APN	1	46,116,300 (GRCm38)	splice site	probably benign
IGL01460:Dnah7b	APN	1	46,139,704 (GRCm38)	missense	possibly damaging	0.82
IGL01576:Dnah7b	APN	1	46,268,653 (GRCm38)	missense	probably damaging	1.00
IGL01693:Dnah7b	APN	1	46,358,147 (GRCm38)	missense	probably benign	0.29
IGL01838:Dnah7b	APN	1	46,358,137 (GRCm38)	nonsense	probably null
IGL01906:Dnah7b	APN	1	46,175,453 (GRCm38)	missense	probably damaging	1.00
IGL01960:Dnah7b	APN	1	46,124,337 (GRCm38)	splice site	probably benign
IGL01989:Dnah7b	APN	1	46,289,534 (GRCm38)	missense	probably damaging	1.00
IGL02127:Dnah7b	APN	1	46,139,875 (GRCm38)	missense	probably benign
IGL02213:Dnah7b	APN	1	46,233,592 (GRCm38)	missense	probably damaging	0.97
IGL02267:Dnah7b	APN	1	46,226,930 (GRCm38)	missense	probably damaging	1.00
IGL02349:Dnah7b	APN	1	46,099,503 (GRCm38)	nonsense	probably null
IGL02381:Dnah7b	APN	1	46,277,120 (GRCm38)	missense	probably damaging	1.00
IGL02473:Dnah7b	APN	1	46,234,193 (GRCm38)	missense	probably damaging	1.00
IGL02484:Dnah7b	APN	1	46,195,318 (GRCm38)	missense	probably damaging	1.00
IGL02590:Dnah7b	APN	1	46,123,777 (GRCm38)	missense	probably benign	0.02
IGL02655:Dnah7b	APN	1	46,116,301 (GRCm38)	splice site	probably benign
IGL02704:Dnah7b	APN	1	46,142,133 (GRCm38)	missense	probably benign	0.03
IGL02719:Dnah7b	APN	1	46,099,608 (GRCm38)	splice site	probably benign
IGL02745:Dnah7b	APN	1	46,195,029 (GRCm38)	splice site	probably benign
IGL02818:Dnah7b	APN	1	46,290,808 (GRCm38)	missense	probably damaging	1.00
IGL02892:Dnah7b	APN	1	46,119,298 (GRCm38)	missense	possibly damaging	0.79
IGL03285:Dnah7b	APN	1	46,182,375 (GRCm38)	missense	probably benign	0.00
IGL03354:Dnah7b	APN	1	46,085,689 (GRCm38)	missense	probably damaging	1.00
IGL03355:Dnah7b	APN	1	46,119,304 (GRCm38)	missense	probably benign	0.18
BB001:Dnah7b	UTSW	1	46,219,430 (GRCm38)	missense	probably benign	0.04
BB011:Dnah7b	UTSW	1	46,219,430 (GRCm38)	missense	probably benign	0.04
PIT4305001:Dnah7b	UTSW	1	46,373,348 (GRCm38)	missense	probably damaging	1.00
R0116:Dnah7b	UTSW	1	46,213,360 (GRCm38)	missense	possibly damaging	0.94
R0145:Dnah7b	UTSW	1	46,223,178 (GRCm38)	missense	probably damaging	1.00
R0230:Dnah7b	UTSW	1	46,219,348 (GRCm38)	missense	probably damaging	1.00
R0302:Dnah7b	UTSW	1	46,123,777 (GRCm38)	missense	probably benign	0.26
R0313:Dnah7b	UTSW	1	46,207,643 (GRCm38)	missense	probably damaging	1.00
R0317:Dnah7b	UTSW	1	46,134,656 (GRCm38)	missense	probably damaging	1.00
R0352:Dnah7b	UTSW	1	46,277,126 (GRCm38)	missense	probably damaging	0.98
R0363:Dnah7b	UTSW	1	46,236,788 (GRCm38)	missense	probably damaging	0.99
R0379:Dnah7b	UTSW	1	46,140,176 (GRCm38)	missense	probably benign	0.00
R0502:Dnah7b	UTSW	1	46,219,544 (GRCm38)	missense	probably damaging	0.96
R0602:Dnah7b	UTSW	1	46,324,842 (GRCm38)	missense	probably damaging	1.00
R0631:Dnah7b	UTSW	1	46,240,992 (GRCm38)	missense	probably benign	0.02
R0664:Dnah7b	UTSW	1	46,324,842 (GRCm38)	missense	probably damaging	1.00
R0882:Dnah7b	UTSW	1	46,340,132 (GRCm38)	missense	probably benign	0.00
R0931:Dnah7b	UTSW	1	46,099,612 (GRCm38)	splice site	probably benign
R1035:Dnah7b	UTSW	1	46,124,448 (GRCm38)	missense	probably benign
R1147:Dnah7b	UTSW	1	46,340,266 (GRCm38)	missense	probably damaging	0.99
R1147:Dnah7b	UTSW	1	46,340,266 (GRCm38)	missense	probably damaging	0.99
R1166:Dnah7b	UTSW	1	46,325,810 (GRCm38)	missense	probably damaging	1.00
R1219:Dnah7b	UTSW	1	46,340,120 (GRCm38)	missense	probably benign	0.00
R1318:Dnah7b	UTSW	1	46,099,509 (GRCm38)	missense	possibly damaging	0.80
R1334:Dnah7b	UTSW	1	46,322,335 (GRCm38)	missense	probably damaging	0.99
R1429:Dnah7b	UTSW	1	46,289,656 (GRCm38)	missense	possibly damaging	0.84
R1440:Dnah7b	UTSW	1	46,078,593 (GRCm38)	splice site	probably benign
R1484:Dnah7b	UTSW	1	46,137,543 (GRCm38)	missense	probably benign	0.00
R1529:Dnah7b	UTSW	1	46,177,281 (GRCm38)	missense	probably damaging	1.00
R1544:Dnah7b	UTSW	1	46,066,797 (GRCm38)	missense	unknown
R1607:Dnah7b	UTSW	1	46,290,646 (GRCm38)	missense	probably damaging	1.00
R1609:Dnah7b	UTSW	1	46,352,966 (GRCm38)	missense	probably damaging	1.00
R1652:Dnah7b	UTSW	1	46,175,390 (GRCm38)	nonsense	probably null
R1681:Dnah7b	UTSW	1	46,324,712 (GRCm38)	nonsense	probably null
R1716:Dnah7b	UTSW	1	46,191,783 (GRCm38)	missense	probably damaging	1.00
R1753:Dnah7b	UTSW	1	46,322,335 (GRCm38)	missense	probably damaging	0.99
R1834:Dnah7b	UTSW	1	46,233,759 (GRCm38)	missense	possibly damaging	0.90
R1838:Dnah7b	UTSW	1	46,277,105 (GRCm38)	missense	probably damaging	1.00
R1838:Dnah7b	UTSW	1	46,116,177 (GRCm38)	missense	probably benign	0.04
R1898:Dnah7b	UTSW	1	46,236,714 (GRCm38)	missense	probably benign	0.02
R1962:Dnah7b	UTSW	1	46,242,103 (GRCm38)	missense	possibly damaging	0.95
R2001:Dnah7b	UTSW	1	46,142,087 (GRCm38)	missense	possibly damaging	0.69
R2049:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2076:Dnah7b	UTSW	1	46,242,321 (GRCm38)	nonsense	probably null
R2083:Dnah7b	UTSW	1	46,241,067 (GRCm38)	missense	possibly damaging	0.90
R2140:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2141:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2142:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2165:Dnah7b	UTSW	1	46,097,992 (GRCm38)	splice site	probably benign
R2172:Dnah7b	UTSW	1	46,124,512 (GRCm38)	missense	probably benign	0.12
R2239:Dnah7b	UTSW	1	46,201,184 (GRCm38)	splice site	probably benign
R2247:Dnah7b	UTSW	1	46,277,063 (GRCm38)	missense	probably damaging	1.00
R2267:Dnah7b	UTSW	1	46,233,915 (GRCm38)	missense	probably damaging	1.00
R2405:Dnah7b	UTSW	1	46,362,954 (GRCm38)	missense	probably benign	0.31
R2509:Dnah7b	UTSW	1	46,195,287 (GRCm38)	missense	probably damaging	0.96
R2895:Dnah7b	UTSW	1	46,139,741 (GRCm38)	missense	probably damaging	1.00
R2965:Dnah7b	UTSW	1	46,207,572 (GRCm38)	missense	probably damaging	1.00
R3013:Dnah7b	UTSW	1	46,188,687 (GRCm38)	critical splice donor site	probably null
R3022:Dnah7b	UTSW	1	46,182,423 (GRCm38)	missense	probably damaging	0.99
R3056:Dnah7b	UTSW	1	46,268,709 (GRCm38)	missense	possibly damaging	0.95
R3107:Dnah7b	UTSW	1	46,352,873 (GRCm38)	missense	probably benign	0.00
R3735:Dnah7b	UTSW	1	46,299,875 (GRCm38)	missense	probably benign	0.05
R3898:Dnah7b	UTSW	1	46,243,257 (GRCm38)	missense	probably damaging	1.00
R3944:Dnah7b	UTSW	1	46,137,485 (GRCm38)	missense	probably damaging	1.00
R3983:Dnah7b	UTSW	1	46,233,711 (GRCm38)	missense	possibly damaging	0.88
R4041:Dnah7b	UTSW	1	46,081,495 (GRCm38)	missense	probably benign
R4172:Dnah7b	UTSW	1	46,226,946 (GRCm38)	missense	probably damaging	1.00
R4210:Dnah7b	UTSW	1	46,137,418 (GRCm38)	missense	possibly damaging	0.63
R4306:Dnah7b	UTSW	1	46,221,772 (GRCm38)	missense	probably damaging	0.99
R4391:Dnah7b	UTSW	1	46,337,594 (GRCm38)	splice site	probably null
R4414:Dnah7b	UTSW	1	46,126,680 (GRCm38)	missense	probably benign	0.00
R4495:Dnah7b	UTSW	1	46,085,632 (GRCm38)	missense	probably benign	0.00
R4660:Dnah7b	UTSW	1	46,289,536 (GRCm38)	missense	probably damaging	1.00
R4670:Dnah7b	UTSW	1	46,078,524 (GRCm38)	missense	probably damaging	1.00
R4675:Dnah7b	UTSW	1	46,217,157 (GRCm38)	missense	possibly damaging	0.89
R4685:Dnah7b	UTSW	1	46,211,328 (GRCm38)	missense	probably damaging	1.00
R4727:Dnah7b	UTSW	1	46,207,656 (GRCm38)	missense	probably damaging	1.00
R4735:Dnah7b	UTSW	1	46,066,955 (GRCm38)	missense	unknown
R4780:Dnah7b	UTSW	1	46,353,014 (GRCm38)	missense	probably benign
R4828:Dnah7b	UTSW	1	46,128,112 (GRCm38)	missense	possibly damaging	0.59
R4859:Dnah7b	UTSW	1	46,356,602 (GRCm38)	missense	probably damaging	1.00
R4865:Dnah7b	UTSW	1	46,195,074 (GRCm38)	missense	probably damaging	1.00
R4871:Dnah7b	UTSW	1	46,081,444 (GRCm38)	missense	probably benign	0.21
R4881:Dnah7b	UTSW	1	46,201,318 (GRCm38)	missense	probably damaging	1.00
R4902:Dnah7b	UTSW	1	46,290,775 (GRCm38)	missense	probably benign	0.04
R4960:Dnah7b	UTSW	1	46,233,726 (GRCm38)	missense	probably benign
R5000:Dnah7b	UTSW	1	46,099,503 (GRCm38)	nonsense	probably null
R5005:Dnah7b	UTSW	1	46,242,028 (GRCm38)	missense	probably damaging	0.99
R5026:Dnah7b	UTSW	1	46,187,363 (GRCm38)	missense	probably damaging	0.99
R5080:Dnah7b	UTSW	1	46,182,380 (GRCm38)	nonsense	probably null
R5174:Dnah7b	UTSW	1	46,243,349 (GRCm38)	missense	possibly damaging	0.83
R5178:Dnah7b	UTSW	1	46,358,216 (GRCm38)	missense	possibly damaging	0.50
R5244:Dnah7b	UTSW	1	46,233,858 (GRCm38)	missense	probably damaging	1.00
R5250:Dnah7b	UTSW	1	46,373,354 (GRCm38)	missense	probably damaging	1.00
R5350:Dnah7b	UTSW	1	46,233,689 (GRCm38)	missense	probably benign	0.16
R5380:Dnah7b	UTSW	1	46,217,191 (GRCm38)	missense	probably benign	0.18
R5387:Dnah7b	UTSW	1	46,188,659 (GRCm38)	missense	probably damaging	1.00
R5423:Dnah7b	UTSW	1	46,358,271 (GRCm38)	missense	probably benign	0.01
R5426:Dnah7b	UTSW	1	46,242,206 (GRCm38)	missense	possibly damaging	0.82
R5451:Dnah7b	UTSW	1	46,242,019 (GRCm38)	missense	possibly damaging	0.73
R5459:Dnah7b	UTSW	1	46,109,312 (GRCm38)	missense	probably null
R5479:Dnah7b	UTSW	1	46,223,105 (GRCm38)	missense	probably damaging	1.00
R5583:Dnah7b	UTSW	1	46,242,199 (GRCm38)	missense	probably benign	0.06
R5637:Dnah7b	UTSW	1	46,356,514 (GRCm38)	missense	possibly damaging	0.95
R5641:Dnah7b	UTSW	1	46,268,764 (GRCm38)	splice site	probably null
R5659:Dnah7b	UTSW	1	46,352,849 (GRCm38)	missense	probably damaging	1.00
R5739:Dnah7b	UTSW	1	46,233,992 (GRCm38)	missense	probably damaging	1.00
R5759:Dnah7b	UTSW	1	46,277,120 (GRCm38)	missense	probably damaging	1.00
R5821:Dnah7b	UTSW	1	46,142,132 (GRCm38)	missense	possibly damaging	0.91
R5874:Dnah7b	UTSW	1	46,191,725 (GRCm38)	missense	probably damaging	1.00
R5892:Dnah7b	UTSW	1	46,337,593 (GRCm38)	critical splice donor site	probably null
R5918:Dnah7b	UTSW	1	46,221,643 (GRCm38)	missense	probably benign
R5941:Dnah7b	UTSW	1	46,187,290 (GRCm38)	missense	probably damaging	1.00
R5965:Dnah7b	UTSW	1	46,362,987 (GRCm38)	missense	probably damaging	1.00
R5987:Dnah7b	UTSW	1	46,119,398 (GRCm38)	splice site	probably null
R6041:Dnah7b	UTSW	1	46,289,645 (GRCm38)	missense	probably benign	0.04
R6043:Dnah7b	UTSW	1	46,139,789 (GRCm38)	missense	probably benign
R6049:Dnah7b	UTSW	1	46,085,602 (GRCm38)	missense	probably benign
R6131:Dnah7b	UTSW	1	46,253,466 (GRCm38)	missense	probably damaging	1.00
R6168:Dnah7b	UTSW	1	46,290,703 (GRCm38)	missense	probably damaging	1.00
R6195:Dnah7b	UTSW	1	46,204,269 (GRCm38)	missense	probably damaging	1.00
R6219:Dnah7b	UTSW	1	46,233,585 (GRCm38)	missense	probably benign	0.03
R6226:Dnah7b	UTSW	1	46,126,668 (GRCm38)	missense	probably benign	0.01
R6233:Dnah7b	UTSW	1	46,204,269 (GRCm38)	missense	probably damaging	1.00
R6247:Dnah7b	UTSW	1	46,225,888 (GRCm38)	missense	probably benign
R6273:Dnah7b	UTSW	1	46,242,316 (GRCm38)	missense	possibly damaging	0.94
R6279:Dnah7b	UTSW	1	46,325,886 (GRCm38)	missense	probably damaging	1.00
R6300:Dnah7b	UTSW	1	46,325,886 (GRCm38)	missense	probably damaging	1.00
R6330:Dnah7b	UTSW	1	46,340,175 (GRCm38)	missense	probably damaging	1.00
R6476:Dnah7b	UTSW	1	46,242,204 (GRCm38)	nonsense	probably null
R6494:Dnah7b	UTSW	1	46,099,431 (GRCm38)	missense	probably damaging	1.00
R6762:Dnah7b	UTSW	1	46,224,742 (GRCm38)	missense	probably benign	0.12
R6800:Dnah7b	UTSW	1	46,340,217 (GRCm38)	missense	possibly damaging	0.90
R6838:Dnah7b	UTSW	1	46,191,788 (GRCm38)	missense	probably damaging	1.00
R6937:Dnah7b	UTSW	1	46,195,120 (GRCm38)	missense	probably damaging	1.00
R6940:Dnah7b	UTSW	1	46,119,268 (GRCm38)	missense	probably benign	0.12
R6969:Dnah7b	UTSW	1	46,358,238 (GRCm38)	missense	probably damaging	1.00
R6993:Dnah7b	UTSW	1	46,195,139 (GRCm38)	critical splice donor site	probably null
R7040:Dnah7b	UTSW	1	46,236,809 (GRCm38)	missense	probably benign	0.01
R7117:Dnah7b	UTSW	1	46,352,813 (GRCm38)	critical splice acceptor site	probably null
R7135:Dnah7b	UTSW	1	46,139,710 (GRCm38)	missense	probably damaging	0.99
R7153:Dnah7b	UTSW	1	46,126,804 (GRCm38)	missense	probably benign	0.05
R7189:Dnah7b	UTSW	1	46,242,142 (GRCm38)	missense	probably damaging	1.00
R7237:Dnah7b	UTSW	1	46,139,966 (GRCm38)	missense	probably damaging	0.98
R7243:Dnah7b	UTSW	1	46,083,754 (GRCm38)	missense	probably benign
R7244:Dnah7b	UTSW	1	46,277,143 (GRCm38)	missense	probably damaging	0.99
R7248:Dnah7b	UTSW	1	46,142,085 (GRCm38)	missense	possibly damaging	0.83
R7318:Dnah7b	UTSW	1	46,195,372 (GRCm38)	missense	probably damaging	1.00
R7375:Dnah7b	UTSW	1	46,303,634 (GRCm38)	missense	probably damaging	1.00
R7483:Dnah7b	UTSW	1	46,175,419 (GRCm38)	missense	probably damaging	1.00
R7486:Dnah7b	UTSW	1	46,290,734 (GRCm38)	missense	probably damaging	1.00
R7498:Dnah7b	UTSW	1	46,325,765 (GRCm38)	missense	probably damaging	1.00
R7501:Dnah7b	UTSW	1	46,356,554 (GRCm38)	missense	probably damaging	1.00
R7513:Dnah7b	UTSW	1	46,124,346 (GRCm38)	missense	probably benign	0.06
R7547:Dnah7b	UTSW	1	46,214,413 (GRCm38)	missense	possibly damaging	0.82
R7620:Dnah7b	UTSW	1	46,268,634 (GRCm38)	missense	probably damaging	1.00
R7670:Dnah7b	UTSW	1	46,109,302 (GRCm38)	missense	probably benign
R7676:Dnah7b	UTSW	1	46,234,164 (GRCm38)	nonsense	probably null
R7731:Dnah7b	UTSW	1	46,139,745 (GRCm38)	missense	probably benign	0.00
R7760:Dnah7b	UTSW	1	46,201,253 (GRCm38)	missense	probably damaging	1.00
R7768:Dnah7b	UTSW	1	46,137,474 (GRCm38)	missense	probably benign
R7807:Dnah7b	UTSW	1	46,214,367 (GRCm38)	missense	probably benign
R7895:Dnah7b	UTSW	1	46,249,950 (GRCm38)	missense	probably damaging	1.00
R7911:Dnah7b	UTSW	1	46,139,678 (GRCm38)	missense	probably damaging	1.00
R7924:Dnah7b	UTSW	1	46,219,430 (GRCm38)	missense	probably benign	0.04
R7944:Dnah7b	UTSW	1	46,227,003 (GRCm38)	missense	probably benign
R7946:Dnah7b	UTSW	1	46,233,579 (GRCm38)	missense	probably damaging	1.00
R7983:Dnah7b	UTSW	1	46,243,424 (GRCm38)	missense	probably damaging	1.00
R8012:Dnah7b	UTSW	1	46,243,365 (GRCm38)	missense	probably damaging	1.00
R8069:Dnah7b	UTSW	1	46,224,706 (GRCm38)	nonsense	probably null
R8094:Dnah7b	UTSW	1	46,126,804 (GRCm38)	missense	probably benign	0.01
R8137:Dnah7b	UTSW	1	46,233,753 (GRCm38)	missense	probably damaging	1.00
R8167:Dnah7b	UTSW	1	46,253,511 (GRCm38)	missense	possibly damaging	0.95
R8268:Dnah7b	UTSW	1	46,356,576 (GRCm38)	missense	probably benign	0.43
R8309:Dnah7b	UTSW	1	46,139,872 (GRCm38)	missense	probably damaging	1.00
R8313:Dnah7b	UTSW	1	46,175,296 (GRCm38)	missense	possibly damaging	0.81
R8410:Dnah7b	UTSW	1	46,356,659 (GRCm38)	critical splice donor site	probably null
R8438:Dnah7b	UTSW	1	46,188,679 (GRCm38)	missense	probably damaging	1.00
R8446:Dnah7b	UTSW	1	46,290,715 (GRCm38)	missense	probably damaging	1.00
R8471:Dnah7b	UTSW	1	46,099,490 (GRCm38)	missense	possibly damaging	0.92
R8551:Dnah7b	UTSW	1	46,116,200 (GRCm38)	missense	possibly damaging	0.94
R8711:Dnah7b	UTSW	1	46,175,438 (GRCm38)	missense	probably damaging	1.00
R8745:Dnah7b	UTSW	1	46,182,464 (GRCm38)	missense	possibly damaging	0.82
R8765:Dnah7b	UTSW	1	46,352,999 (GRCm38)	missense	possibly damaging	0.91
R8797:Dnah7b	UTSW	1	46,123,646 (GRCm38)	missense	probably damaging	1.00
R8805:Dnah7b	UTSW	1	46,234,145 (GRCm38)	missense	possibly damaging	0.90
R8830:Dnah7b	UTSW	1	46,191,793 (GRCm38)	missense	probably damaging	1.00
R8861:Dnah7b	UTSW	1	46,241,076 (GRCm38)	missense	possibly damaging	0.82
R8905:Dnah7b	UTSW	1	46,253,374 (GRCm38)	missense	probably damaging	0.99
R9009:Dnah7b	UTSW	1	46,223,072 (GRCm38)	missense	probably benign	0.00
R9058:Dnah7b	UTSW	1	46,243,415 (GRCm38)	missense	probably damaging	1.00
R9130:Dnah7b	UTSW	1	46,134,514 (GRCm38)	missense	probably benign	0.01
R9131:Dnah7b	UTSW	1	46,227,020 (GRCm38)	missense	probably damaging	1.00
R9181:Dnah7b	UTSW	1	46,142,034 (GRCm38)	missense	probably damaging	1.00
R9182:Dnah7b	UTSW	1	46,290,878 (GRCm38)	missense	probably benign	0.06
R9223:Dnah7b	UTSW	1	46,322,260 (GRCm38)	missense	probably benign	0.12
R9391:Dnah7b	UTSW	1	46,233,754 (GRCm38)	nonsense	probably null
R9392:Dnah7b	UTSW	1	46,123,738 (GRCm38)	nonsense	probably null
R9456:Dnah7b	UTSW	1	46,126,793 (GRCm38)	missense	possibly damaging	0.82
R9498:Dnah7b	UTSW	1	46,214,404 (GRCm38)	missense	probably benign	0.27
R9553:Dnah7b	UTSW	1	46,225,796 (GRCm38)	missense	probably damaging	0.99
R9598:Dnah7b	UTSW	1	46,253,461 (GRCm38)	missense	possibly damaging	0.67
R9653:Dnah7b	UTSW	1	46,213,384 (GRCm38)	missense	possibly damaging	0.55
R9781:Dnah7b	UTSW	1	46,337,594 (GRCm38)	splice site	probably null
RF020:Dnah7b	UTSW	1	46,373,261 (GRCm38)	missense	possibly damaging	0.84
V8831:Dnah7b	UTSW	1	46,373,298 (GRCm38)	nonsense	probably null
X0023:Dnah7b	UTSW	1	46,303,577 (GRCm38)	missense	probably benign	0.04

Predicted Primers

PCR Primer
(F):5'- TCCACACCTAGTACCTGTGAAGGAC -3'
(R):5'- TATCAAGGGCAGCCAGTGCAGATTC -3'

Sequencing Primer
(F):5'- CCTGTGAAGGACTTTTAGACCAC -3'
(R):5'- CCAGTGCAGATTCCAGGATG -3'

Posted On

2013-05-23