Incidental Mutation 'R4979:Ly75'
| ID |
384650 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
042574-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4979 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
60292103-60383303 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 60375894 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Serine
at position 144
(G144S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000028362
AA Change: G144S
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: G144S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112533
AA Change: G144S
PolyPhen 2
Score 0.928 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: G144S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151984
|
| Meta Mutation Damage Score |
0.1368 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.4%
|
| Validation Efficiency |
99% (79/80) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
G |
A |
17: 9,001,811 (GRCm38) |
E381K |
probably damaging |
Het |
| Abca1 |
T |
C |
4: 53,085,092 (GRCm38) |
|
probably null |
Het |
| Abca7 |
C |
T |
10: 80,004,783 (GRCm38) |
Q870* |
probably null |
Het |
| Ambp |
C |
T |
4: 63,152,651 (GRCm38) |
V64M |
probably benign |
Het |
| Ank1 |
T |
C |
8: 23,132,196 (GRCm38) |
V1542A |
probably damaging |
Het |
| Anln |
T |
C |
9: 22,376,501 (GRCm38) |
Y168C |
probably benign |
Het |
| Apoa4 |
T |
A |
9: 46,241,505 (GRCm38) |
N29K |
probably benign |
Het |
| Arfgef1 |
T |
C |
1: 10,213,109 (GRCm38) |
T192A |
probably damaging |
Het |
| Atad2b |
G |
T |
12: 5,034,513 (GRCm38) |
D1420Y |
probably damaging |
Het |
| Baiap3 |
A |
G |
17: 25,246,362 (GRCm38) |
W648R |
possibly damaging |
Het |
| Bank1 |
A |
G |
3: 136,254,901 (GRCm38) |
L198P |
probably damaging |
Het |
| Bicd2 |
A |
G |
13: 49,379,464 (GRCm38) |
K509E |
possibly damaging |
Het |
| Cacna1e |
T |
C |
1: 154,413,993 (GRCm38) |
D1821G |
probably damaging |
Het |
| Ccdc80 |
G |
A |
16: 45,116,287 (GRCm38) |
V692M |
possibly damaging |
Het |
| Ccdc88a |
C |
T |
11: 29,482,133 (GRCm38) |
Q308* |
probably null |
Het |
| Ccl8 |
T |
C |
11: 82,116,147 (GRCm38) |
V62A |
probably damaging |
Het |
| Clspn |
C |
A |
4: 126,578,386 (GRCm38) |
P951Q |
probably damaging |
Het |
| Cngb1 |
T |
A |
8: 95,259,157 (GRCm38) |
I858F |
probably damaging |
Het |
| Cspp1 |
T |
A |
1: 10,126,463 (GRCm38) |
N900K |
probably damaging |
Het |
| Ctc1 |
C |
T |
11: 69,033,502 (GRCm38) |
A960V |
probably damaging |
Het |
| Ctnnd2 |
A |
G |
15: 31,009,075 (GRCm38) |
E1106G |
probably damaging |
Het |
| Dido1 |
C |
T |
2: 180,660,813 (GRCm38) |
R1766H |
probably damaging |
Het |
| Dipk1a |
A |
T |
5: 107,909,534 (GRCm38) |
L386* |
probably null |
Het |
| Dnajc13 |
G |
T |
9: 104,186,723 (GRCm38) |
N1341K |
probably damaging |
Het |
| Dnase1l1 |
C |
T |
X: 74,277,038 (GRCm38) |
|
probably null |
Homo |
| E2f8 |
G |
A |
7: 48,875,170 (GRCm38) |
|
probably benign |
Het |
| Entpd8 |
A |
G |
2: 25,082,955 (GRCm38) |
D91G |
possibly damaging |
Het |
| Fars2 |
A |
G |
13: 36,204,581 (GRCm38) |
R18G |
possibly damaging |
Het |
| Fcgbp |
A |
G |
7: 28,117,570 (GRCm38) |
S2486G |
probably benign |
Het |
| Fibin |
C |
T |
2: 110,362,618 (GRCm38) |
D60N |
possibly damaging |
Het |
| Fpgs |
A |
G |
2: 32,687,367 (GRCm38) |
|
probably benign |
Het |
| Galnt15 |
A |
G |
14: 32,043,290 (GRCm38) |
D303G |
probably damaging |
Het |
| Gli3 |
C |
A |
13: 15,724,464 (GRCm38) |
T812K |
possibly damaging |
Het |
| Gpbar1 |
G |
C |
1: 74,279,245 (GRCm38) |
A216P |
probably benign |
Het |
| Grin2d |
A |
G |
7: 45,857,933 (GRCm38) |
I448T |
probably benign |
Het |
| Il21 |
C |
A |
3: 37,232,504 (GRCm38) |
S21I |
probably damaging |
Het |
| Iqce |
G |
T |
5: 140,691,621 (GRCm38) |
D148E |
probably damaging |
Het |
| Iqcg |
T |
A |
16: 33,019,514 (GRCm38) |
E354V |
probably damaging |
Het |
| Iws1 |
T |
C |
18: 32,093,267 (GRCm38) |
|
probably benign |
Het |
| Marco |
C |
A |
1: 120,494,225 (GRCm38) |
M83I |
probably benign |
Het |
| Mettl6 |
A |
T |
14: 31,479,795 (GRCm38) |
L185H |
probably damaging |
Het |
| Mppe1 |
C |
T |
18: 67,229,702 (GRCm38) |
G154D |
probably damaging |
Het |
| Mrpl42 |
T |
C |
10: 95,490,375 (GRCm38) |
E85G |
probably benign |
Het |
| Neb |
A |
G |
2: 52,189,909 (GRCm38) |
V5518A |
probably damaging |
Het |
| Or12d13 |
A |
T |
17: 37,336,868 (GRCm38) |
F121L |
probably benign |
Het |
| Or52p1 |
T |
A |
7: 104,618,605 (GRCm38) |
F317I |
probably null |
Het |
| Or5b105 |
A |
T |
19: 13,102,689 (GRCm38) |
I199N |
probably damaging |
Het |
| Or7a42 |
T |
A |
10: 78,955,932 (GRCm38) |
C242* |
probably null |
Het |
| Or7d10 |
G |
T |
9: 19,920,359 (GRCm38) |
S50I |
probably benign |
Het |
| Perm1 |
A |
G |
4: 156,217,577 (GRCm38) |
T193A |
probably benign |
Het |
| Prkd2 |
T |
A |
7: 16,848,727 (GRCm38) |
C172S |
probably damaging |
Het |
| Prr23a3 |
T |
A |
9: 98,865,378 (GRCm38) |
D128E |
possibly damaging |
Het |
| Prss28 |
A |
G |
17: 25,309,737 (GRCm38) |
Y51C |
probably damaging |
Het |
| Psmb1 |
A |
T |
17: 15,476,189 (GRCm38) |
M85K |
probably benign |
Het |
| Rae1 |
T |
A |
2: 173,012,608 (GRCm38) |
|
probably benign |
Het |
| Rasal1 |
A |
G |
5: 120,678,676 (GRCm38) |
D759G |
probably benign |
Het |
| Rcvrn |
G |
A |
11: 67,695,420 (GRCm38) |
G2R |
probably damaging |
Het |
| Robo3 |
C |
T |
9: 37,423,344 (GRCm38) |
A597T |
probably damaging |
Het |
| Rsf1 |
GCG |
GCGACGGCGCCG |
7: 97,579,907 (GRCm38) |
|
probably benign |
Homo |
| Sdcbp |
T |
A |
4: 6,378,980 (GRCm38) |
Y22* |
probably null |
Het |
| Sin3a |
T |
C |
9: 57,118,076 (GRCm38) |
F1069L |
probably damaging |
Het |
| Slitrk3 |
C |
T |
3: 73,049,796 (GRCm38) |
V548I |
possibly damaging |
Het |
| Tbc1d22a |
A |
G |
15: 86,391,086 (GRCm38) |
H403R |
probably damaging |
Het |
| Tbr1 |
G |
T |
2: 61,805,249 (GRCm38) |
|
probably null |
Het |
| Tiam2 |
T |
A |
17: 3,505,710 (GRCm38) |
D65E |
probably damaging |
Het |
| Tpcn2 |
A |
G |
7: 145,260,096 (GRCm38) |
S488P |
probably benign |
Het |
| Trav9-2 |
T |
C |
14: 53,591,238 (GRCm38) |
S22P |
probably damaging |
Het |
| Trim34a |
T |
A |
7: 104,247,862 (GRCm38) |
N44K |
probably benign |
Het |
| Unc79 |
C |
G |
12: 103,112,432 (GRCm38) |
P1619A |
probably benign |
Het |
| Usp22 |
A |
T |
11: 61,157,216 (GRCm38) |
V426E |
probably damaging |
Het |
| Vhl |
A |
T |
6: 113,624,198 (GRCm38) |
M20L |
unknown |
Het |
| Vmn1r215 |
G |
A |
13: 23,075,894 (GRCm38) |
A35T |
probably benign |
Het |
| Vmn1r222 |
G |
A |
13: 23,232,432 (GRCm38) |
L204F |
possibly damaging |
Het |
| Zfp871 |
A |
T |
17: 32,775,855 (GRCm38) |
H115Q |
probably damaging |
Het |
| Zpr1 |
T |
A |
9: 46,278,342 (GRCm38) |
F340L |
probably benign |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,376,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,354,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,321,692 (GRCm38) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,376,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,301,015 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,338,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,299,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,311,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,352,356 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,354,452 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,358,507 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,293,781 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,383,182 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,321,900 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,308,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,376,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,352,070 (GRCm38) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,352,352 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,339,457 (GRCm38) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,318,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,306,404 (GRCm38) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,308,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,316,221 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,293,758 (GRCm38) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,368,757 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,327,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,314,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,311,777 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,349,913 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,334,554 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,352,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,354,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,330,773 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,308,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,352,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,375,963 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,334,487 (GRCm38) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,365,111 (GRCm38) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,365,145 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,352,381 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,299,082 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,318,439 (GRCm38) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,383,146 (GRCm38) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,375,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,368,873 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,318,376 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,308,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,306,405 (GRCm38) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,306,434 (GRCm38) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,376,184 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,323,852 (GRCm38) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,329,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,334,515 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,334,474 (GRCm38) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,334,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,293,827 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,365,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,332,934 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,314,228 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,318,385 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,334,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,323,926 (GRCm38) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,348,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,331,089 (GRCm38) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,358,559 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,316,098 (GRCm38) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,330,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,327,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,338,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,323,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,306,328 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,354,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,352,133 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,350,004 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAACTGAGTTGTGCGTGTTC -3'
(R):5'- TGCCTCGGCCTCGATATTAC -3'
Sequencing Primer
(F):5'- GTGTGTGCAAAACCTTCAGC -3'
(R):5'- TCGGCCTCGATATTACCAAAG -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation