Incidental Mutation 'R4993:Zfp462'
| ID |
384987 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp462
|
| Ensembl Gene |
ENSMUSG00000060206 |
| Gene Name |
zinc finger protein 462 |
| Synonyms |
9430078C22Rik, Zfpip, Gt4-2 |
| MMRRC Submission |
042587-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.881)
|
| Stock # |
R4993 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
54945048-55083563 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 55051204 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 2226
(M2226V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000095677
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030131]
[ENSMUST00000079605]
[ENSMUST00000098070]
|
| AlphaFold |
B1AWL2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000030131
AA Change: M1138V
PolyPhen 2
Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000030131
Gene: ENSMUSG00000060206
AA Change: M1138V
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
35 |
58 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
106 |
129 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
153 |
176 |
3.47e0 |
SMART |
|
ZnF_C2H2
|
210 |
233 |
7.29e0 |
SMART |
|
ZnF_C2H2
|
311 |
334 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
356 |
379 |
6.57e0 |
SMART |
|
ZnF_C2H2
|
418 |
441 |
5.34e-1 |
SMART |
|
low complexity region
|
450 |
463 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
501 |
524 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
538 |
561 |
5.34e0 |
SMART |
|
ZnF_C2H2
|
608 |
631 |
6.4e0 |
SMART |
|
low complexity region
|
655 |
676 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
687 |
711 |
3.05e1 |
SMART |
|
ZnF_C2H2
|
733 |
755 |
1.08e-1 |
SMART |
|
low complexity region
|
757 |
771 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
809 |
831 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
892 |
914 |
3.11e-2 |
SMART |
|
ZnF_C2H2
|
926 |
948 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
955 |
978 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
984 |
1007 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
1092 |
1115 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
1121 |
1144 |
5.48e0 |
SMART |
|
ZnF_C2H2
|
1155 |
1177 |
6.13e-1 |
SMART |
|
ZnF_C2H2
|
1201 |
1223 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
1229 |
1252 |
2.02e-1 |
SMART |
|
low complexity region
|
1273 |
1296 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1315 |
1337 |
2.2e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000079605
AA Change: M1139V
PolyPhen 2
Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000078555
Gene: ENSMUSG00000060206
AA Change: M1139V
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
35 |
58 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
106 |
129 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
153 |
176 |
3.47e0 |
SMART |
|
ZnF_C2H2
|
210 |
233 |
7.29e0 |
SMART |
|
ZnF_C2H2
|
311 |
334 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
356 |
379 |
6.57e0 |
SMART |
|
ZnF_C2H2
|
418 |
441 |
5.34e-1 |
SMART |
|
low complexity region
|
450 |
463 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
501 |
524 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
538 |
561 |
5.34e0 |
SMART |
|
ZnF_C2H2
|
608 |
631 |
6.4e0 |
SMART |
|
low complexity region
|
655 |
676 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
687 |
711 |
3.05e1 |
SMART |
|
ZnF_C2H2
|
733 |
755 |
1.08e-1 |
SMART |
|
low complexity region
|
757 |
771 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
809 |
831 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
893 |
915 |
3.11e-2 |
SMART |
|
ZnF_C2H2
|
927 |
949 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
956 |
979 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
985 |
1008 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
1093 |
1116 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
1122 |
1145 |
5.48e0 |
SMART |
|
ZnF_C2H2
|
1156 |
1178 |
6.13e-1 |
SMART |
|
ZnF_C2H2
|
1202 |
1224 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
1230 |
1253 |
2.02e-1 |
SMART |
|
low complexity region
|
1274 |
1297 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1316 |
1338 |
2.2e-2 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000098070
AA Change: M2226V
PolyPhen 2
Score 0.619 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000095677
Gene: ENSMUSG00000060206
AA Change: M2226V
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
27 |
5.81e-2 |
SMART |
|
low complexity region
|
81 |
94 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
108 |
131 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
162 |
185 |
4.65e-1 |
SMART |
|
low complexity region
|
194 |
215 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
243 |
266 |
4.98e-1 |
SMART |
|
low complexity region
|
332 |
343 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
440 |
463 |
1.01e-1 |
SMART |
|
ZnF_C2H2
|
471 |
493 |
2.86e-1 |
SMART |
|
low complexity region
|
503 |
515 |
N/A |
INTRINSIC |
|
low complexity region
|
536 |
592 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
593 |
616 |
2.53e-2 |
SMART |
|
low complexity region
|
707 |
736 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
835 |
858 |
5.62e0 |
SMART |
|
ZnF_C2H2
|
878 |
900 |
2.14e0 |
SMART |
|
ZnF_C2H2
|
917 |
940 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
1023 |
1046 |
5.72e-1 |
SMART |
|
low complexity region
|
1092 |
1100 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1107 |
1130 |
4.23e0 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
1254 |
1277 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
1301 |
1324 |
3.47e0 |
SMART |
|
ZnF_C2H2
|
1358 |
1381 |
7.29e0 |
SMART |
|
ZnF_C2H2
|
1459 |
1482 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
1504 |
1527 |
6.57e0 |
SMART |
|
ZnF_C2H2
|
1566 |
1589 |
5.34e-1 |
SMART |
|
low complexity region
|
1598 |
1611 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1649 |
1672 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
1686 |
1709 |
5.34e0 |
SMART |
|
ZnF_C2H2
|
1756 |
1779 |
6.4e0 |
SMART |
|
low complexity region
|
1803 |
1824 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1835 |
1859 |
3.05e1 |
SMART |
|
ZnF_C2H2
|
1881 |
1903 |
1.08e-1 |
SMART |
|
low complexity region
|
1905 |
1919 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1957 |
1979 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
2014 |
2036 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
2043 |
2066 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
2072 |
2095 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
2180 |
2203 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
2209 |
2232 |
5.48e0 |
SMART |
|
ZnF_C2H2
|
2243 |
2265 |
6.13e-1 |
SMART |
|
ZnF_C2H2
|
2289 |
2311 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
2317 |
2340 |
2.02e-1 |
SMART |
|
low complexity region
|
2361 |
2384 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
2403 |
2425 |
2.2e-2 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to C2H2-type zinc finger family of proteins. It contains multiple C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930505A04Rik |
C |
T |
11: 30,376,349 (GRCm39) |
V173M |
probably damaging |
Het |
| 9130008F23Rik |
G |
T |
17: 41,191,052 (GRCm39) |
Q126K |
probably benign |
Het |
| Abca15 |
C |
A |
7: 120,000,941 (GRCm39) |
N1492K |
probably damaging |
Het |
| Afap1l2 |
C |
T |
19: 56,906,472 (GRCm39) |
D402N |
probably damaging |
Het |
| Akap11 |
A |
G |
14: 78,750,408 (GRCm39) |
F660L |
probably damaging |
Het |
| Bcl3 |
T |
C |
7: 19,554,102 (GRCm39) |
T89A |
probably benign |
Het |
| Bub1b |
T |
C |
2: 118,467,251 (GRCm39) |
I858T |
possibly damaging |
Het |
| Cdk19 |
A |
G |
10: 40,352,214 (GRCm39) |
D288G |
possibly damaging |
Het |
| Cyp2d34 |
T |
A |
15: 82,502,530 (GRCm39) |
D202V |
probably damaging |
Het |
| Dip2c |
T |
G |
13: 9,625,259 (GRCm39) |
Y584* |
probably null |
Het |
| Dpf3 |
A |
T |
12: 83,378,635 (GRCm39) |
|
probably null |
Het |
| Drp2 |
G |
A |
X: 133,342,065 (GRCm39) |
R567H |
probably damaging |
Homo |
| Emid1 |
G |
T |
11: 5,081,512 (GRCm39) |
Q212K |
probably benign |
Het |
| Esm1 |
C |
T |
13: 113,349,933 (GRCm39) |
Q118* |
probably null |
Het |
| Fahd2a |
T |
G |
2: 127,278,284 (GRCm39) |
I308L |
probably benign |
Het |
| Fanci |
T |
C |
7: 79,085,126 (GRCm39) |
*851Q |
probably null |
Het |
| Fastkd1 |
C |
A |
2: 69,533,084 (GRCm39) |
V428F |
probably damaging |
Het |
| Fat2 |
A |
T |
11: 55,173,918 (GRCm39) |
I2265N |
probably damaging |
Het |
| Gale |
C |
A |
4: 135,694,171 (GRCm39) |
H191Q |
probably damaging |
Het |
| Ghsr |
T |
A |
3: 27,426,403 (GRCm39) |
V153E |
possibly damaging |
Het |
| Gpc6 |
A |
G |
14: 117,861,951 (GRCm39) |
N289S |
possibly damaging |
Het |
| Hoxb6 |
A |
T |
11: 96,191,537 (GRCm39) |
Y153F |
probably damaging |
Het |
| Ints3 |
T |
C |
3: 90,322,814 (GRCm39) |
T139A |
probably benign |
Het |
| Irf2bp2 |
A |
G |
8: 127,319,410 (GRCm39) |
S256P |
probably benign |
Het |
| Klf4 |
G |
T |
4: 55,530,640 (GRCm39) |
P148Q |
probably damaging |
Het |
| Loxl1 |
T |
G |
9: 58,219,820 (GRCm39) |
H117P |
probably damaging |
Het |
| Lpl |
A |
G |
8: 69,348,445 (GRCm39) |
K225E |
probably benign |
Het |
| Lrba |
T |
A |
3: 86,267,344 (GRCm39) |
V1678D |
probably damaging |
Het |
| Med1 |
A |
T |
11: 98,054,730 (GRCm39) |
F398Y |
probably damaging |
Het |
| Mfap2 |
T |
C |
4: 140,742,889 (GRCm39) |
*186Q |
probably null |
Het |
| Mfsd3 |
T |
C |
15: 76,586,182 (GRCm39) |
L105P |
probably damaging |
Het |
| Mlxip |
T |
G |
5: 123,533,357 (GRCm39) |
I122S |
probably damaging |
Het |
| Mmrn2 |
A |
T |
14: 34,118,355 (GRCm39) |
Y107F |
probably damaging |
Het |
| Mtg1 |
G |
T |
7: 139,720,196 (GRCm39) |
D88Y |
probably null |
Het |
| Mutyh |
T |
A |
4: 116,675,132 (GRCm39) |
S426R |
probably benign |
Het |
| Myo16 |
C |
T |
8: 10,526,094 (GRCm39) |
T878I |
probably damaging |
Het |
| Myo9a |
T |
A |
9: 59,768,755 (GRCm39) |
Y912* |
probably null |
Het |
| Ncor1 |
A |
C |
11: 62,234,167 (GRCm39) |
I669R |
probably damaging |
Het |
| Ndufs1 |
T |
C |
1: 63,202,935 (GRCm39) |
I210V |
probably benign |
Het |
| Nek9 |
A |
G |
12: 85,357,194 (GRCm39) |
C657R |
probably damaging |
Het |
| Noct |
C |
T |
3: 51,157,442 (GRCm39) |
T260I |
probably damaging |
Het |
| Nr1h4 |
A |
T |
10: 89,334,042 (GRCm39) |
M102K |
probably benign |
Het |
| Obscn |
G |
A |
11: 59,015,587 (GRCm39) |
R1054C |
possibly damaging |
Het |
| Or10ag58 |
T |
A |
2: 87,265,496 (GRCm39) |
F222I |
probably benign |
Het |
| Or1j20 |
C |
A |
2: 36,760,000 (GRCm39) |
Q141K |
probably benign |
Het |
| Or2a57 |
A |
G |
6: 43,213,390 (GRCm39) |
M283V |
possibly damaging |
Het |
| Or51ah3 |
T |
A |
7: 103,210,524 (GRCm39) |
I280N |
possibly damaging |
Het |
| Or52z14 |
A |
T |
7: 103,252,863 (GRCm39) |
M1L |
probably benign |
Het |
| Or5p75-ps1 |
G |
A |
7: 108,107,450 (GRCm39) |
M62I |
probably damaging |
Het |
| Otol1 |
C |
A |
3: 69,926,211 (GRCm39) |
Q129K |
probably benign |
Het |
| Otx1 |
A |
T |
11: 21,948,532 (GRCm39) |
|
probably null |
Het |
| Pcdhac2 |
C |
A |
18: 37,279,304 (GRCm39) |
N761K |
probably damaging |
Het |
| Pde1c |
A |
T |
6: 56,127,609 (GRCm39) |
M452K |
probably damaging |
Het |
| Phkg2 |
T |
C |
7: 127,173,113 (GRCm39) |
Y24H |
probably damaging |
Het |
| Pigr |
G |
A |
1: 130,769,554 (GRCm39) |
D122N |
probably benign |
Het |
| Prg4 |
C |
T |
1: 150,336,432 (GRCm39) |
C97Y |
probably damaging |
Het |
| Ptdss1 |
T |
C |
13: 67,093,352 (GRCm39) |
V64A |
probably benign |
Het |
| Ralgapa2 |
T |
C |
2: 146,289,231 (GRCm39) |
K324E |
probably damaging |
Het |
| Rfx5 |
G |
A |
3: 94,863,126 (GRCm39) |
V73I |
probably benign |
Het |
| Riiad1 |
T |
C |
3: 94,380,170 (GRCm39) |
T42A |
probably benign |
Het |
| Rims2 |
T |
C |
15: 39,317,841 (GRCm39) |
V640A |
possibly damaging |
Het |
| Rnpep |
G |
T |
1: 135,190,770 (GRCm39) |
S592Y |
possibly damaging |
Het |
| Scap |
T |
C |
9: 110,207,458 (GRCm39) |
L431P |
probably damaging |
Het |
| Siglec1 |
T |
A |
2: 130,915,281 (GRCm39) |
I1437F |
possibly damaging |
Het |
| Skic3 |
T |
A |
13: 76,331,055 (GRCm39) |
M1495K |
probably damaging |
Het |
| Skint1 |
T |
C |
4: 111,885,530 (GRCm39) |
|
probably null |
Het |
| Slc44a1 |
A |
G |
4: 53,543,644 (GRCm39) |
E396G |
probably damaging |
Het |
| Slc4a2 |
T |
C |
5: 24,639,867 (GRCm39) |
F521S |
probably damaging |
Het |
| Smarcc1 |
T |
A |
9: 110,004,129 (GRCm39) |
S394R |
probably damaging |
Het |
| Socs1 |
A |
G |
16: 10,602,549 (GRCm39) |
S63P |
probably benign |
Het |
| Spopfm2 |
C |
T |
3: 94,083,623 (GRCm39) |
G63R |
probably damaging |
Het |
| Sun1 |
T |
G |
5: 139,211,088 (GRCm39) |
S20A |
possibly damaging |
Het |
| Tac4 |
A |
T |
11: 95,156,068 (GRCm39) |
K50* |
probably null |
Het |
| Tasor |
T |
A |
14: 27,151,071 (GRCm39) |
W16R |
possibly damaging |
Het |
| Tcaf2 |
A |
G |
6: 42,619,574 (GRCm39) |
I151T |
probably damaging |
Het |
| Tcf4 |
T |
C |
18: 69,814,840 (GRCm39) |
V587A |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,571,253 (GRCm39) |
K24801* |
probably null |
Het |
| Tuba3b |
G |
T |
6: 145,566,999 (GRCm39) |
M413I |
possibly damaging |
Het |
| Ufl1 |
C |
T |
4: 25,267,832 (GRCm39) |
A280T |
possibly damaging |
Het |
| Ugt2b5 |
T |
A |
5: 87,287,532 (GRCm39) |
I212L |
probably benign |
Het |
| Umodl1 |
A |
G |
17: 31,205,459 (GRCm39) |
T685A |
probably benign |
Het |
| Uqcrc1 |
T |
A |
9: 108,773,878 (GRCm39) |
V183D |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,642,917 (GRCm39) |
N4093S |
probably benign |
Het |
| Vmn1r167 |
C |
T |
7: 23,204,653 (GRCm39) |
S121N |
probably damaging |
Het |
| Vmn1r47 |
A |
G |
6: 89,999,740 (GRCm39) |
S291G |
possibly damaging |
Het |
| Vmn2r108 |
A |
G |
17: 20,701,449 (GRCm39) |
V17A |
probably benign |
Het |
| Vmn2r58 |
T |
A |
7: 41,487,176 (GRCm39) |
H573L |
probably benign |
Het |
| Xirp1 |
C |
T |
9: 119,847,858 (GRCm39) |
V342I |
probably damaging |
Het |
| Zfp467 |
G |
A |
6: 48,415,963 (GRCm39) |
H230Y |
probably damaging |
Het |
| Zfp595 |
T |
A |
13: 67,464,465 (GRCm39) |
K599N |
probably damaging |
Het |
| Zfp819 |
C |
A |
7: 43,266,720 (GRCm39) |
T401K |
probably benign |
Het |
|
| Other mutations in Zfp462 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00162:Zfp462
|
APN |
4 |
55,011,483 (GRCm39) |
splice site |
probably null |
|
|
IGL00421:Zfp462
|
APN |
4 |
55,023,576 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00899:Zfp462
|
APN |
4 |
55,007,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Zfp462
|
APN |
4 |
55,013,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01627:Zfp462
|
APN |
4 |
55,008,912 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01715:Zfp462
|
APN |
4 |
55,008,586 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01862:Zfp462
|
APN |
4 |
55,023,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01878:Zfp462
|
APN |
4 |
55,010,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01913:Zfp462
|
APN |
4 |
55,012,138 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02029:Zfp462
|
APN |
4 |
55,079,395 (GRCm39) |
splice site |
probably benign |
|
|
IGL02338:Zfp462
|
APN |
4 |
55,010,292 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02552:Zfp462
|
APN |
4 |
55,010,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02623:Zfp462
|
APN |
4 |
55,012,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02750:Zfp462
|
APN |
4 |
55,060,236 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL02815:Zfp462
|
APN |
4 |
55,051,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Zfp462
|
APN |
4 |
55,080,785 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
FR4304:Zfp462
|
UTSW |
4 |
55,009,758 (GRCm39) |
unclassified |
probably benign |
|
|
FR4304:Zfp462
|
UTSW |
4 |
55,009,757 (GRCm39) |
unclassified |
probably benign |
|
|
FR4737:Zfp462
|
UTSW |
4 |
55,009,760 (GRCm39) |
unclassified |
probably benign |
|
|
FR4737:Zfp462
|
UTSW |
4 |
55,009,758 (GRCm39) |
unclassified |
probably benign |
|
|
FR4976:Zfp462
|
UTSW |
4 |
55,009,761 (GRCm39) |
unclassified |
probably benign |
|
|
FR4976:Zfp462
|
UTSW |
4 |
55,009,760 (GRCm39) |
unclassified |
probably benign |
|
|
P0035:Zfp462
|
UTSW |
4 |
55,009,086 (GRCm39) |
missense |
probably benign |
|
|
R0052:Zfp462
|
UTSW |
4 |
55,011,762 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0143:Zfp462
|
UTSW |
4 |
55,023,402 (GRCm39) |
splice site |
probably benign |
|
|
R0145:Zfp462
|
UTSW |
4 |
55,010,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0315:Zfp462
|
UTSW |
4 |
55,079,314 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0349:Zfp462
|
UTSW |
4 |
55,008,768 (GRCm39) |
missense |
probably benign |
|
|
R0359:Zfp462
|
UTSW |
4 |
55,013,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0413:Zfp462
|
UTSW |
4 |
55,010,534 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0554:Zfp462
|
UTSW |
4 |
55,013,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0616:Zfp462
|
UTSW |
4 |
55,011,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0631:Zfp462
|
UTSW |
4 |
55,007,563 (GRCm39) |
start codon destroyed |
possibly damaging |
0.60 |
|
R1086:Zfp462
|
UTSW |
4 |
55,013,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1499:Zfp462
|
UTSW |
4 |
55,060,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1509:Zfp462
|
UTSW |
4 |
55,007,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1526:Zfp462
|
UTSW |
4 |
55,009,002 (GRCm39) |
missense |
probably benign |
|
|
R1541:Zfp462
|
UTSW |
4 |
55,008,928 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1691:Zfp462
|
UTSW |
4 |
55,013,489 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1843:Zfp462
|
UTSW |
4 |
55,010,010 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2086:Zfp462
|
UTSW |
4 |
55,010,830 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Zfp462
|
UTSW |
4 |
55,008,496 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2148:Zfp462
|
UTSW |
4 |
55,013,670 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2179:Zfp462
|
UTSW |
4 |
55,009,524 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2325:Zfp462
|
UTSW |
4 |
55,013,712 (GRCm39) |
missense |
probably benign |
|
|
R2352:Zfp462
|
UTSW |
4 |
55,008,313 (GRCm39) |
missense |
probably null |
|
|
R2566:Zfp462
|
UTSW |
4 |
55,008,522 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3879:Zfp462
|
UTSW |
4 |
55,060,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3969:Zfp462
|
UTSW |
4 |
55,012,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4273:Zfp462
|
UTSW |
4 |
55,008,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4413:Zfp462
|
UTSW |
4 |
55,012,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4510:Zfp462
|
UTSW |
4 |
55,008,934 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4511:Zfp462
|
UTSW |
4 |
55,008,934 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4609:Zfp462
|
UTSW |
4 |
55,011,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Zfp462
|
UTSW |
4 |
55,012,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp462
|
UTSW |
4 |
55,009,349 (GRCm39) |
missense |
probably benign |
|
|
R4682:Zfp462
|
UTSW |
4 |
55,011,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Zfp462
|
UTSW |
4 |
55,008,612 (GRCm39) |
missense |
probably benign |
|
|
R4744:Zfp462
|
UTSW |
4 |
55,011,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Zfp462
|
UTSW |
4 |
55,013,476 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4819:Zfp462
|
UTSW |
4 |
55,060,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4827:Zfp462
|
UTSW |
4 |
55,012,213 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4854:Zfp462
|
UTSW |
4 |
55,010,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4879:Zfp462
|
UTSW |
4 |
55,009,444 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4891:Zfp462
|
UTSW |
4 |
55,060,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5118:Zfp462
|
UTSW |
4 |
55,010,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5171:Zfp462
|
UTSW |
4 |
55,016,986 (GRCm39) |
splice site |
probably null |
|
|
R5173:Zfp462
|
UTSW |
4 |
55,011,115 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5221:Zfp462
|
UTSW |
4 |
55,016,887 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5268:Zfp462
|
UTSW |
4 |
55,012,299 (GRCm39) |
missense |
probably benign |
|
|
R5314:Zfp462
|
UTSW |
4 |
55,013,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5429:Zfp462
|
UTSW |
4 |
55,060,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5518:Zfp462
|
UTSW |
4 |
55,009,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5525:Zfp462
|
UTSW |
4 |
55,050,281 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5620:Zfp462
|
UTSW |
4 |
55,013,464 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5775:Zfp462
|
UTSW |
4 |
55,010,590 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6126:Zfp462
|
UTSW |
4 |
55,023,573 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6280:Zfp462
|
UTSW |
4 |
55,010,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6325:Zfp462
|
UTSW |
4 |
55,080,680 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6542:Zfp462
|
UTSW |
4 |
55,023,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6612:Zfp462
|
UTSW |
4 |
55,012,324 (GRCm39) |
splice site |
probably null |
|
|
R6663:Zfp462
|
UTSW |
4 |
55,008,933 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6872:Zfp462
|
UTSW |
4 |
55,012,326 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6889:Zfp462
|
UTSW |
4 |
55,007,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6896:Zfp462
|
UTSW |
4 |
55,009,544 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6913:Zfp462
|
UTSW |
4 |
55,007,775 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6988:Zfp462
|
UTSW |
4 |
55,080,716 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7131:Zfp462
|
UTSW |
4 |
55,009,380 (GRCm39) |
missense |
probably benign |
|
|
R7151:Zfp462
|
UTSW |
4 |
55,051,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7684:Zfp462
|
UTSW |
4 |
55,008,908 (GRCm39) |
missense |
probably benign |
|
|
R7741:Zfp462
|
UTSW |
4 |
55,008,637 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7750:Zfp462
|
UTSW |
4 |
55,016,958 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7812:Zfp462
|
UTSW |
4 |
55,008,509 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7863:Zfp462
|
UTSW |
4 |
55,007,747 (GRCm39) |
missense |
probably benign |
|
|
R7898:Zfp462
|
UTSW |
4 |
55,012,995 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7993:Zfp462
|
UTSW |
4 |
55,011,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp462
|
UTSW |
4 |
55,011,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8023:Zfp462
|
UTSW |
4 |
55,073,106 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8394:Zfp462
|
UTSW |
4 |
55,011,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8669:Zfp462
|
UTSW |
4 |
55,051,313 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8877:Zfp462
|
UTSW |
4 |
55,011,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8980:Zfp462
|
UTSW |
4 |
55,009,681 (GRCm39) |
unclassified |
probably benign |
|
|
R9023:Zfp462
|
UTSW |
4 |
55,007,563 (GRCm39) |
start codon destroyed |
probably null |
0.00 |
|
R9243:Zfp462
|
UTSW |
4 |
55,009,595 (GRCm39) |
nonsense |
probably null |
|
|
R9378:Zfp462
|
UTSW |
4 |
55,011,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9417:Zfp462
|
UTSW |
4 |
55,016,988 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9476:Zfp462
|
UTSW |
4 |
55,080,735 (GRCm39) |
missense |
probably benign |
|
|
R9510:Zfp462
|
UTSW |
4 |
55,080,735 (GRCm39) |
missense |
probably benign |
|
|
R9610:Zfp462
|
UTSW |
4 |
55,009,545 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9628:Zfp462
|
UTSW |
4 |
55,009,423 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GAGTAGTTGCCTCTGTATCTCC -3'
(R):5'- GCTGAGGCACTAACCAACTC -3'
Sequencing Primer
(F):5'- CCCTCTCTGTTCCTTGATGG -3'
(R):5'- GCAGCAGCAGCACTACG -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation