Incidental Mutation 'R4983:Arap2'
| ID |
385717 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
042577-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4983 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 62833868 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 866
(H866Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076623
AA Change: H866Q
PolyPhen 2
Score 0.980 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: H866Q
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201373
|
| Meta Mutation Damage Score |
0.1052 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
97% (103/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933411K16Rik |
T |
G |
19: 42,041,515 (GRCm39) |
S215R |
possibly damaging |
Het |
| Abcc9 |
T |
C |
6: 142,627,867 (GRCm39) |
M388V |
probably benign |
Het |
| Acbd6 |
A |
C |
1: 155,477,275 (GRCm39) |
T154P |
probably benign |
Het |
| Ago1 |
T |
C |
4: 126,347,447 (GRCm39) |
D434G |
probably damaging |
Het |
| Ankib1 |
A |
T |
5: 3,819,652 (GRCm39) |
M89K |
probably benign |
Het |
| Armh3 |
T |
C |
19: 45,939,146 (GRCm39) |
T335A |
probably benign |
Het |
| Capn12 |
A |
T |
7: 28,589,795 (GRCm39) |
H622L |
probably benign |
Het |
| Capns2 |
T |
G |
8: 93,628,530 (GRCm39) |
F140V |
probably damaging |
Het |
| Catsper1 |
T |
G |
19: 5,385,991 (GRCm39) |
F75V |
probably benign |
Het |
| Ccdc24 |
T |
C |
4: 117,729,297 (GRCm39) |
N16S |
probably benign |
Het |
| Cdkn2aip |
A |
T |
8: 48,165,964 (GRCm39) |
L114Q |
probably damaging |
Het |
| Cenpe |
T |
A |
3: 134,940,689 (GRCm39) |
S649R |
probably damaging |
Het |
| Chgb |
A |
T |
2: 132,635,602 (GRCm39) |
R515W |
probably damaging |
Het |
| Chrnb1 |
A |
G |
11: 69,684,804 (GRCm39) |
F123S |
probably damaging |
Het |
| Copz2 |
A |
T |
11: 96,748,377 (GRCm39) |
|
probably null |
Het |
| Cspp1 |
T |
A |
1: 10,196,688 (GRCm39) |
N900K |
probably damaging |
Het |
| Daw1 |
C |
A |
1: 83,165,719 (GRCm39) |
A178E |
probably benign |
Het |
| Dnase1l1 |
C |
T |
X: 73,320,644 (GRCm39) |
|
probably null |
Homo |
| Epb41l5 |
T |
C |
1: 119,482,801 (GRCm39) |
D629G |
probably benign |
Het |
| Erap1 |
A |
G |
13: 74,838,829 (GRCm39) |
E925G |
probably benign |
Het |
| Exoc7 |
A |
C |
11: 116,180,095 (GRCm39) |
F657V |
probably damaging |
Het |
| Fam210b |
G |
C |
2: 172,187,585 (GRCm39) |
A2P |
probably damaging |
Homo |
| Fry |
A |
G |
5: 150,321,719 (GRCm39) |
E1018G |
probably damaging |
Het |
| Galc |
A |
T |
12: 98,209,027 (GRCm39) |
L15* |
probably null |
Het |
| Gm11232 |
T |
A |
4: 71,675,138 (GRCm39) |
K121N |
possibly damaging |
Het |
| Hectd1 |
A |
T |
12: 51,831,045 (GRCm39) |
D931E |
probably benign |
Het |
| Hecw2 |
T |
C |
1: 53,871,830 (GRCm39) |
H1372R |
probably benign |
Het |
| Ighv3-2 |
T |
A |
12: 113,997,606 (GRCm39) |
|
noncoding transcript |
Het |
| Kcns2 |
T |
G |
15: 34,839,751 (GRCm39) |
S371R |
probably damaging |
Het |
| Kif23 |
T |
C |
9: 61,843,985 (GRCm39) |
K175E |
probably benign |
Het |
| Kmt2c |
G |
A |
5: 25,500,509 (GRCm39) |
R436W |
possibly damaging |
Het |
| Lama5 |
A |
G |
2: 179,835,242 (GRCm39) |
S1317P |
probably benign |
Het |
| Lce1e |
T |
C |
3: 92,615,135 (GRCm39) |
S71G |
unknown |
Het |
| Lrrc37a |
T |
A |
11: 103,388,444 (GRCm39) |
E2327V |
unknown |
Het |
| Map3k20 |
A |
G |
2: 72,232,411 (GRCm39) |
M356V |
probably benign |
Het |
| Med12l |
C |
T |
3: 59,169,350 (GRCm39) |
A1580V |
probably damaging |
Het |
| Metap2 |
G |
T |
10: 93,725,462 (GRCm39) |
T30K |
possibly damaging |
Het |
| Mysm1 |
T |
A |
4: 94,861,207 (GRCm39) |
T53S |
probably benign |
Het |
| Nasp |
A |
T |
4: 116,459,382 (GRCm39) |
D717E |
probably damaging |
Het |
| Ndnf |
G |
A |
6: 65,680,555 (GRCm39) |
R278H |
possibly damaging |
Het |
| Neb |
A |
T |
2: 52,106,273 (GRCm39) |
N4205K |
probably damaging |
Het |
| Nebl |
A |
T |
2: 17,380,082 (GRCm39) |
I764N |
possibly damaging |
Het |
| Nucb1 |
A |
G |
7: 45,148,313 (GRCm39) |
Y131H |
probably damaging |
Het |
| Or14c39 |
A |
C |
7: 86,343,687 (GRCm39) |
T8P |
probably benign |
Het |
| Or1e22 |
A |
G |
11: 73,377,623 (GRCm39) |
I9T |
probably benign |
Het |
| Or5l14 |
G |
T |
2: 87,793,042 (GRCm39) |
H65N |
probably benign |
Het |
| Oscp1 |
T |
A |
4: 125,970,555 (GRCm39) |
C115S |
probably benign |
Het |
| Paip2 |
C |
T |
18: 35,746,412 (GRCm39) |
R59C |
possibly damaging |
Het |
| Pate10 |
T |
G |
9: 35,653,465 (GRCm39) |
F90V |
probably benign |
Het |
| Pcdhga4 |
G |
A |
18: 37,819,572 (GRCm39) |
D374N |
probably damaging |
Het |
| Pcolce |
G |
T |
5: 137,603,936 (GRCm39) |
|
probably benign |
Het |
| Pcyox1l |
T |
C |
18: 61,832,468 (GRCm39) |
E193G |
probably damaging |
Het |
| Pde6b |
A |
T |
5: 108,573,196 (GRCm39) |
Q522L |
probably benign |
Het |
| Peg10 |
T |
TCCG |
6: 4,756,451 (GRCm39) |
|
probably benign |
Het |
| Phf11a |
A |
G |
14: 59,521,887 (GRCm39) |
F95L |
probably benign |
Het |
| Pja2 |
A |
C |
17: 64,616,053 (GRCm39) |
S281A |
probably benign |
Het |
| Plekhm2 |
A |
G |
4: 141,361,687 (GRCm39) |
F272S |
probably damaging |
Het |
| Pom121l2 |
T |
C |
13: 22,167,984 (GRCm39) |
S752P |
probably benign |
Het |
| Ppl |
T |
C |
16: 4,906,582 (GRCm39) |
T1238A |
possibly damaging |
Het |
| Prmt7 |
A |
G |
8: 106,976,995 (GRCm39) |
Y569C |
probably damaging |
Het |
| Prss37 |
G |
A |
6: 40,493,070 (GRCm39) |
T132I |
probably benign |
Het |
| Psmf1 |
A |
T |
2: 151,571,377 (GRCm39) |
|
probably benign |
Het |
| Ptprj |
A |
C |
2: 90,290,876 (GRCm39) |
I528S |
probably damaging |
Het |
| Reg1 |
A |
G |
6: 78,405,196 (GRCm39) |
T140A |
possibly damaging |
Het |
| Rtn4 |
A |
G |
11: 29,657,217 (GRCm39) |
N457S |
probably benign |
Het |
| Rusf1 |
C |
T |
7: 127,875,645 (GRCm39) |
|
probably benign |
Het |
| Scn9a |
T |
C |
2: 66,396,614 (GRCm39) |
K93R |
probably benign |
Het |
| Sec16a |
A |
G |
2: 26,329,531 (GRCm39) |
V828A |
probably benign |
Het |
| Sec23b |
T |
A |
2: 144,423,873 (GRCm39) |
D507E |
probably benign |
Het |
| Sirt4 |
A |
T |
5: 115,620,850 (GRCm39) |
F107L |
probably benign |
Het |
| Slc14a2 |
A |
T |
18: 78,193,616 (GRCm39) |
L862Q |
probably damaging |
Het |
| Slc16a4 |
T |
C |
3: 107,208,176 (GRCm39) |
S229P |
probably benign |
Het |
| Slc37a3 |
A |
T |
6: 39,329,651 (GRCm39) |
C185* |
probably null |
Het |
| Slc5a2 |
A |
T |
7: 127,870,982 (GRCm39) |
*154C |
probably null |
Het |
| Snx17 |
A |
G |
5: 31,353,138 (GRCm39) |
S42G |
possibly damaging |
Het |
| Tgm6 |
T |
C |
2: 129,983,113 (GRCm39) |
V234A |
probably damaging |
Het |
| Thbs4 |
A |
G |
13: 92,927,207 (GRCm39) |
M94T |
probably benign |
Het |
| Thtpa |
A |
G |
14: 55,309,605 (GRCm39) |
|
probably benign |
Het |
| Tie1 |
T |
C |
4: 118,340,952 (GRCm39) |
E343G |
probably damaging |
Het |
| Tmem145 |
A |
G |
7: 25,008,027 (GRCm39) |
I238V |
probably benign |
Het |
| Tmprss11f |
T |
C |
5: 86,685,858 (GRCm39) |
S170G |
probably benign |
Het |
| Tnk2 |
T |
A |
16: 32,499,283 (GRCm39) |
D865E |
probably damaging |
Het |
| Ttll8 |
T |
C |
15: 88,809,785 (GRCm39) |
E337G |
probably benign |
Het |
| Ttn |
G |
A |
2: 76,697,790 (GRCm39) |
|
probably benign |
Het |
| Tubgcp6 |
T |
C |
15: 88,990,494 (GRCm39) |
E710G |
probably damaging |
Het |
| Txndc2 |
T |
A |
17: 65,945,055 (GRCm39) |
H374L |
probably benign |
Het |
| Unc80 |
G |
T |
1: 66,713,891 (GRCm39) |
|
probably null |
Het |
| Vmn2r23 |
G |
A |
6: 123,710,308 (GRCm39) |
C537Y |
probably damaging |
Het |
| Vmn2r45 |
A |
G |
7: 8,486,116 (GRCm39) |
F391L |
probably damaging |
Het |
| Vstm4 |
A |
T |
14: 32,641,202 (GRCm39) |
T262S |
probably benign |
Het |
| Zfp180 |
C |
T |
7: 23,805,503 (GRCm39) |
R641C |
probably damaging |
Het |
| Zfp979 |
A |
T |
4: 147,698,371 (GRCm39) |
S113T |
possibly damaging |
Het |
| Zswim4 |
C |
T |
8: 84,953,296 (GRCm39) |
|
probably null |
Het |
| Zswim5 |
T |
A |
4: 116,842,883 (GRCm39) |
M876K |
possibly damaging |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Arap2
|
UTSW |
5 |
62,835,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4715:Arap2
|
UTSW |
5 |
62,906,437 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5426:Arap2
|
UTSW |
5 |
62,800,159 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Arap2
|
UTSW |
5 |
62,828,297 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7107:Arap2
|
UTSW |
5 |
62,763,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Arap2
|
UTSW |
5 |
62,855,728 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTGCAAAGAAGCACACACTTAAGC -3'
(R):5'- GAATGCATAGGCTCTGTGTGC -3'
Sequencing Primer
(F):5'- GAAGCACACACTTAAGCCATAG -3'
(R):5'- CTGCAGTTGTGAAGCCAGATG -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation