Incidental Mutation 'R4992:Nlrp9a'
| ID |
386254 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9a
|
| Ensembl Gene |
ENSMUSG00000054102 |
| Gene Name |
NLR family, pyrin domain containing 9A |
| Synonyms |
Nalp9a, Nalp-theta, D7Ertd565e |
| MMRRC Submission |
042586-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
R4992 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
26234448-26273573 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 26256811 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 54
(V54A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000120498
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071780]
[ENSMUST00000108387]
[ENSMUST00000117252]
[ENSMUST00000122040]
[ENSMUST00000153452]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071780
AA Change: V143A
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000071685
Gene: ENSMUSG00000054102
AA Change: V143A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108387
AA Change: V143A
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000104024
Gene: ENSMUSG00000054102
AA Change: V143A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
7.7e-33 |
PFAM |
|
LRR
|
631 |
658 |
1.42e0 |
SMART |
|
LRR
|
692 |
719 |
1.42e0 |
SMART |
|
LRR
|
748 |
775 |
2.32e-1 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
1.12e-3 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.27e-4 |
SMART |
|
LRR
|
891 |
918 |
2.02e2 |
SMART |
|
LRR
|
919 |
946 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117252
AA Change: V143A
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000112398
Gene: ENSMUSG00000054102
AA Change: V143A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
8.8e-34 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
Blast:LRR
|
666 |
692 |
1e-5 |
BLAST |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.39e0 |
SMART |
|
LRR
|
807 |
834 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122040
AA Change: V143A
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000113318
Gene: ENSMUSG00000054102
AA Change: V143A
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153452
AA Change: V54A
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000120498
Gene: ENSMUSG00000054102
AA Change: V54A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NACHT
|
54 |
222 |
6.9e-33 |
PFAM |
|
LRR
|
542 |
569 |
1.42e0 |
SMART |
|
LRR
|
603 |
630 |
1.42e0 |
SMART |
|
Blast:LRR
|
632 |
657 |
1e-5 |
BLAST |
|
LRR
|
659 |
686 |
2.32e-1 |
SMART |
|
LRR
|
688 |
715 |
3e0 |
SMART |
|
LRR
|
716 |
743 |
1.12e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.7%
|
| Validation Efficiency |
98% (84/86) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930407I10Rik |
G |
A |
15: 81,948,203 (GRCm39) |
R700Q |
possibly damaging |
Het |
| 4930444P10Rik |
T |
A |
1: 16,151,101 (GRCm39) |
E27V |
probably damaging |
Het |
| Acsm4 |
T |
A |
7: 119,310,640 (GRCm39) |
I509N |
probably benign |
Het |
| Asb18 |
T |
C |
1: 89,880,585 (GRCm39) |
M143V |
probably benign |
Het |
| Birc6 |
A |
G |
17: 74,996,251 (GRCm39) |
D4475G |
probably benign |
Het |
| Bsn |
A |
T |
9: 107,992,747 (GRCm39) |
S1002T |
probably damaging |
Het |
| Bub3 |
T |
C |
7: 131,162,535 (GRCm39) |
S33P |
probably damaging |
Het |
| Ccna1 |
T |
A |
3: 54,957,311 (GRCm39) |
R35S |
probably damaging |
Het |
| Cdc23 |
T |
A |
18: 34,779,972 (GRCm39) |
M119L |
probably benign |
Het |
| Ces1a |
A |
G |
8: 93,771,650 (GRCm39) |
V49A |
probably benign |
Het |
| Chi3l1 |
A |
T |
1: 134,116,364 (GRCm39) |
E282D |
probably benign |
Het |
| Crocc |
G |
A |
4: 140,773,977 (GRCm39) |
A220V |
probably damaging |
Het |
| Cstf1 |
A |
G |
2: 172,219,720 (GRCm39) |
Y277C |
probably damaging |
Het |
| D930020B18Rik |
C |
G |
10: 121,490,666 (GRCm39) |
P89A |
probably damaging |
Het |
| D930020B18Rik |
C |
T |
10: 121,490,667 (GRCm39) |
P89L |
probably damaging |
Het |
| Dennd5a |
A |
G |
7: 109,493,919 (GRCm39) |
S1262P |
probably damaging |
Het |
| Dnajb5 |
G |
A |
4: 42,953,386 (GRCm39) |
|
probably null |
Het |
| E330034G19Rik |
A |
G |
14: 24,357,064 (GRCm39) |
K200R |
unknown |
Het |
| Ect2l |
A |
G |
10: 18,048,477 (GRCm39) |
F156S |
probably benign |
Het |
| Egf |
T |
C |
3: 129,505,179 (GRCm39) |
|
probably null |
Het |
| Elmo1 |
T |
C |
13: 20,526,689 (GRCm39) |
F413S |
probably damaging |
Het |
| Elmo3 |
T |
A |
8: 106,036,133 (GRCm39) |
Y607* |
probably null |
Het |
| Eno3 |
A |
G |
11: 70,549,473 (GRCm39) |
D98G |
probably damaging |
Het |
| Ephb2 |
A |
G |
4: 136,388,150 (GRCm39) |
V651A |
probably damaging |
Het |
| Fbp1 |
C |
T |
13: 63,012,888 (GRCm39) |
V102I |
probably benign |
Het |
| Gcn1 |
T |
C |
5: 115,737,225 (GRCm39) |
V1321A |
probably benign |
Het |
| Gimd1 |
A |
T |
3: 132,340,718 (GRCm39) |
Y78F |
probably benign |
Het |
| Glmn |
T |
G |
5: 107,705,167 (GRCm39) |
D483A |
probably damaging |
Het |
| Gsr |
C |
T |
8: 34,183,941 (GRCm39) |
T401I |
probably damaging |
Het |
| Htr3b |
G |
A |
9: 48,870,518 (GRCm39) |
H62Y |
possibly damaging |
Het |
| Ifna6 |
T |
C |
4: 88,745,777 (GRCm39) |
V42A |
probably benign |
Het |
| Igkv4-80 |
A |
C |
6: 68,993,649 (GRCm39) |
S81A |
probably benign |
Het |
| Inpp4b |
A |
T |
8: 82,759,837 (GRCm39) |
R627S |
probably damaging |
Het |
| Kif13a |
C |
T |
13: 46,930,639 (GRCm39) |
V142M |
probably damaging |
Het |
| Lims1 |
A |
C |
10: 58,246,063 (GRCm39) |
|
probably benign |
Het |
| Ltn1 |
T |
C |
16: 87,202,475 (GRCm39) |
T1059A |
possibly damaging |
Het |
| Lyst |
T |
C |
13: 13,835,748 (GRCm39) |
L1810P |
probably damaging |
Het |
| Mboat1 |
T |
G |
13: 30,386,343 (GRCm39) |
I119R |
possibly damaging |
Het |
| Mgat3 |
T |
A |
15: 80,096,743 (GRCm39) |
D523E |
probably benign |
Het |
| Mphosph9 |
T |
C |
5: 124,442,253 (GRCm39) |
E395G |
probably damaging |
Het |
| Mtcl1 |
G |
T |
17: 66,649,834 (GRCm39) |
P1877Q |
probably damaging |
Het |
| Myo6 |
T |
C |
9: 80,190,792 (GRCm39) |
V781A |
possibly damaging |
Het |
| Ncoa3 |
T |
A |
2: 165,911,859 (GRCm39) |
M1395K |
probably benign |
Het |
| Nhlrc2 |
T |
A |
19: 56,558,966 (GRCm39) |
D150E |
probably benign |
Het |
| Or1e32 |
G |
A |
11: 73,705,146 (GRCm39) |
T254I |
probably damaging |
Het |
| Or3a1d |
A |
G |
11: 74,238,023 (GRCm39) |
I129T |
probably damaging |
Het |
| Parp14 |
A |
T |
16: 35,661,512 (GRCm39) |
C1479S |
probably benign |
Het |
| Pdcd1lg2 |
T |
C |
19: 29,423,484 (GRCm39) |
V176A |
probably damaging |
Het |
| Pibf1 |
T |
A |
14: 99,388,103 (GRCm39) |
N416K |
probably damaging |
Het |
| Pip4p1 |
A |
G |
14: 51,166,690 (GRCm39) |
V179A |
probably damaging |
Het |
| Polb |
A |
T |
8: 23,135,087 (GRCm39) |
V115E |
probably damaging |
Het |
| Polq |
T |
A |
16: 36,881,524 (GRCm39) |
N1229K |
possibly damaging |
Het |
| Ppp1r21 |
A |
T |
17: 88,876,508 (GRCm39) |
D440V |
probably benign |
Het |
| Ppp2ca |
T |
A |
11: 52,004,033 (GRCm39) |
H63Q |
possibly damaging |
Het |
| Prl7a1 |
C |
T |
13: 27,819,669 (GRCm39) |
|
probably null |
Het |
| Rgs1 |
C |
A |
1: 144,122,060 (GRCm39) |
K77N |
probably damaging |
Het |
| Rnf112 |
T |
A |
11: 61,343,537 (GRCm39) |
I100F |
possibly damaging |
Het |
| Rnf139 |
G |
T |
15: 58,770,325 (GRCm39) |
E117* |
probably null |
Het |
| Robo1 |
G |
A |
16: 72,776,756 (GRCm39) |
V743I |
probably damaging |
Het |
| Scarf1 |
T |
C |
11: 75,416,841 (GRCm39) |
V761A |
probably benign |
Het |
| Scarf1 |
T |
C |
11: 75,413,056 (GRCm39) |
L434P |
probably damaging |
Het |
| Sgsm1 |
A |
T |
5: 113,430,486 (GRCm39) |
S300T |
possibly damaging |
Het |
| Slc26a7 |
T |
G |
4: 14,565,508 (GRCm39) |
T192P |
probably damaging |
Het |
| Smarcc2 |
A |
G |
10: 128,310,579 (GRCm39) |
K403E |
probably damaging |
Het |
| Snai3 |
G |
A |
8: 123,183,071 (GRCm39) |
T158M |
possibly damaging |
Het |
| Spata31d1a |
T |
C |
13: 59,850,965 (GRCm39) |
N388D |
probably benign |
Het |
| Sptlc3 |
G |
A |
2: 139,437,923 (GRCm39) |
V406I |
probably benign |
Het |
| Tgds |
A |
C |
14: 118,355,175 (GRCm39) |
Y197D |
probably damaging |
Het |
| Tll1 |
G |
T |
8: 64,546,978 (GRCm39) |
R323S |
probably damaging |
Het |
| Trim14 |
A |
G |
4: 46,507,110 (GRCm39) |
Y369H |
probably damaging |
Het |
| Ube2nl |
C |
T |
7: 61,199,112 (GRCm39) |
|
noncoding transcript |
Het |
| Ube3a |
T |
A |
7: 58,934,568 (GRCm39) |
D560E |
possibly damaging |
Het |
| Vmn2r10 |
A |
G |
5: 109,145,592 (GRCm39) |
V505A |
possibly damaging |
Het |
| Vmn2r114 |
T |
G |
17: 23,510,765 (GRCm39) |
I572L |
probably benign |
Het |
| Vmn2r26 |
A |
T |
6: 124,003,070 (GRCm39) |
Q160L |
probably benign |
Het |
| Vmn2r75 |
A |
C |
7: 85,815,375 (GRCm39) |
|
probably null |
Het |
| Vps8 |
A |
G |
16: 21,280,158 (GRCm39) |
K336E |
possibly damaging |
Het |
| Zfp324 |
T |
C |
7: 12,703,300 (GRCm39) |
S32P |
probably benign |
Het |
| Zfp366 |
T |
C |
13: 99,366,003 (GRCm39) |
I388T |
possibly damaging |
Het |
| Zfp68 |
A |
T |
5: 138,605,599 (GRCm39) |
N203K |
possibly damaging |
Het |
| Zhx2 |
A |
T |
15: 57,686,983 (GRCm39) |
N784I |
probably damaging |
Het |
|
| Other mutations in Nlrp9a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00659:Nlrp9a
|
APN |
7 |
26,257,050 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL00895:Nlrp9a
|
APN |
7 |
26,258,103 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp9a
|
APN |
7 |
26,257,519 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01148:Nlrp9a
|
APN |
7 |
26,257,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01368:Nlrp9a
|
APN |
7 |
26,257,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Nlrp9a
|
APN |
7 |
26,256,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01952:Nlrp9a
|
APN |
7 |
26,257,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02245:Nlrp9a
|
APN |
7 |
26,257,318 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02449:Nlrp9a
|
APN |
7 |
26,264,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02702:Nlrp9a
|
APN |
7 |
26,264,381 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02944:Nlrp9a
|
APN |
7 |
26,258,076 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03183:Nlrp9a
|
APN |
7 |
26,256,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0005:Nlrp9a
|
UTSW |
7 |
26,273,213 (GRCm39) |
splice site |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0013:Nlrp9a
|
UTSW |
7 |
26,270,650 (GRCm39) |
splice site |
probably null |
|
|
R0086:Nlrp9a
|
UTSW |
7 |
26,257,972 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0659:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1126:Nlrp9a
|
UTSW |
7 |
26,260,166 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1500:Nlrp9a
|
UTSW |
7 |
26,267,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1585:Nlrp9a
|
UTSW |
7 |
26,258,093 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1594:Nlrp9a
|
UTSW |
7 |
26,269,932 (GRCm39) |
nonsense |
probably null |
|
|
R1968:Nlrp9a
|
UTSW |
7 |
26,264,366 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1989:Nlrp9a
|
UTSW |
7 |
26,273,338 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2057:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2058:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2059:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2188:Nlrp9a
|
UTSW |
7 |
26,264,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Nlrp9a
|
UTSW |
7 |
26,273,277 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3110:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3112:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3237:Nlrp9a
|
UTSW |
7 |
26,270,810 (GRCm39) |
nonsense |
probably null |
|
|
R3545:Nlrp9a
|
UTSW |
7 |
26,256,757 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3805:Nlrp9a
|
UTSW |
7 |
26,264,277 (GRCm39) |
nonsense |
probably null |
|
|
R4005:Nlrp9a
|
UTSW |
7 |
26,257,975 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4057:Nlrp9a
|
UTSW |
7 |
26,270,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4529:Nlrp9a
|
UTSW |
7 |
26,270,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Nlrp9a
|
UTSW |
7 |
26,256,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4908:Nlrp9a
|
UTSW |
7 |
26,250,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4972:Nlrp9a
|
UTSW |
7 |
26,269,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5042:Nlrp9a
|
UTSW |
7 |
26,270,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrp9a
|
UTSW |
7 |
26,256,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5449:Nlrp9a
|
UTSW |
7 |
26,257,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5644:Nlrp9a
|
UTSW |
7 |
26,257,993 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5734:Nlrp9a
|
UTSW |
7 |
26,270,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5905:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5978:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6066:Nlrp9a
|
UTSW |
7 |
26,257,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6082:Nlrp9a
|
UTSW |
7 |
26,267,402 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6171:Nlrp9a
|
UTSW |
7 |
26,258,188 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6352:Nlrp9a
|
UTSW |
7 |
26,257,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Nlrp9a
|
UTSW |
7 |
26,250,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6540:Nlrp9a
|
UTSW |
7 |
26,256,817 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7039:Nlrp9a
|
UTSW |
7 |
26,267,367 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7151:Nlrp9a
|
UTSW |
7 |
26,256,672 (GRCm39) |
nonsense |
probably null |
|
|
R7173:Nlrp9a
|
UTSW |
7 |
26,257,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7214:Nlrp9a
|
UTSW |
7 |
26,250,463 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7226:Nlrp9a
|
UTSW |
7 |
26,258,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7250:Nlrp9a
|
UTSW |
7 |
26,258,143 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7293:Nlrp9a
|
UTSW |
7 |
26,270,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Nlrp9a
|
UTSW |
7 |
26,257,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7586:Nlrp9a
|
UTSW |
7 |
26,256,721 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7844:Nlrp9a
|
UTSW |
7 |
26,262,006 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8073:Nlrp9a
|
UTSW |
7 |
26,260,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8136:Nlrp9a
|
UTSW |
7 |
26,256,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8400:Nlrp9a
|
UTSW |
7 |
26,264,431 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8415:Nlrp9a
|
UTSW |
7 |
26,256,925 (GRCm39) |
missense |
probably benign |
|
|
R8774:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8774-TAIL:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8882:Nlrp9a
|
UTSW |
7 |
26,257,703 (GRCm39) |
nonsense |
probably null |
|
|
R9023:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9031:Nlrp9a
|
UTSW |
7 |
26,257,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9090:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9196:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Nlrp9a
|
UTSW |
7 |
26,257,656 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9265:Nlrp9a
|
UTSW |
7 |
26,258,038 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9271:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9384:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9402:Nlrp9a
|
UTSW |
7 |
26,270,030 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9424:Nlrp9a
|
UTSW |
7 |
26,260,178 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9620:Nlrp9a
|
UTSW |
7 |
26,250,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9696:Nlrp9a
|
UTSW |
7 |
26,275,033 (GRCm39) |
missense |
unknown |
|
|
R9728:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9744:Nlrp9a
|
UTSW |
7 |
26,267,266 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9794:Nlrp9a
|
UTSW |
7 |
26,264,302 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1176:Nlrp9a
|
UTSW |
7 |
26,257,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9a
|
UTSW |
7 |
26,256,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGGAGTATTCTATTCCTAACTGCC -3'
(R):5'- TGAAGATTCAGGCAACGTACTTG -3'
Sequencing Primer
(F):5'- GCCCTTTATTCTGATTTTTCAAATCC -3'
(R):5'- TCAGGCAACGTACTTGAGATAAGCTC -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation