Mutagenetix > Incidental Mutation

Incidental Mutation 'R0426:Dnah3'

38650

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

MMRRC Submission

038628-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.089) question?

Stock #

R0426 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

119922671-120095280 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 119943572 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 3539 (E3539G)

Ref Sequence

ENSEMBL: ENSMUSP00000042857 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000207270] [ENSMUST00000208424] [ENSMUST00000208701] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000046993
AA Change: E3539G

PolyPhen 2 Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: E3539G

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000207270

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207680

Predicted Effect

probably benign
Transcript: ENSMUST00000208424

Predicted Effect

probably benign
Transcript: ENSMUST00000208701
AA Change: E560G

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

Predicted Effect

probably benign
Transcript: ENSMUST00000209154
AA Change: E3528G

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.7%
20x: 93.9%

Validation Efficiency

96% (86/90)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 87 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A830010M20Rik	C	T	5: 107,510,373 (GRCm38)	T1603I	probably damaging	Het
Abca8b	G	T	11: 109,955,027 (GRCm38)		probably benign	Het
Acadl	A	T	1: 66,841,646 (GRCm38)	F320L	probably damaging	Het
Acsbg1	T	C	9: 54,622,746 (GRCm38)	D222G	probably benign	Het
Anapc15	A	G	7: 101,898,033 (GRCm38)	T39A	probably benign	Het
Ano3	A	T	2: 110,661,174 (GRCm38)	V919E	probably damaging	Het
Arhgef12	T	C	9: 42,970,990 (GRCm38)		probably null	Het
Atad5	T	A	11: 80,112,832 (GRCm38)	I1091N	probably benign	Het
Atf1	A	T	15: 100,232,827 (GRCm38)	H26L	possibly damaging	Het
Atp10a	T	C	7: 58,784,734 (GRCm38)	M252T	probably benign	Het
Cd55	C	T	1: 130,448,372 (GRCm38)	R347H	probably benign	Het
Cdc27	A	C	11: 104,513,027 (GRCm38)		probably null	Het
Cdh9	G	A	15: 16,823,454 (GRCm38)		probably null	Het
Cdk11b	T	C	4: 155,642,512 (GRCm38)		probably benign	Het
Cep70	A	G	9: 99,297,684 (GRCm38)	D567G	probably benign	Het
Cep78	A	T	19: 15,970,970 (GRCm38)	Y382*	probably null	Het
Col9a2	T	C	4: 121,044,660 (GRCm38)		probably benign	Het
Cyp2d12	G	A	15: 82,558,963 (GRCm38)	D409N	probably benign	Het
Ddx39	A	G	8: 83,721,769 (GRCm38)	T217A	probably benign	Het
Dennd1b	T	A	1: 139,170,196 (GRCm38)	D733E	probably benign	Het
Dicer1	A	G	12: 104,702,542 (GRCm38)	S1294P	probably damaging	Het
Dnmbp	A	G	19: 43,852,436 (GRCm38)		probably benign	Het
Dysf	T	C	6: 84,149,757 (GRCm38)	L1332P	probably damaging	Het
F5	A	G	1: 164,182,840 (GRCm38)	D380G	probably damaging	Het
Fam160a2	A	C	7: 105,389,473 (GRCm38)	C186W	probably damaging	Het
Fam171a1	T	C	2: 3,225,396 (GRCm38)	V522A	probably benign	Het
Galr2	C	A	11: 116,281,691 (GRCm38)	A69D	probably damaging	Het
Grk2	T	C	19: 4,290,600 (GRCm38)		probably null	Het
Gtf3c1	A	T	7: 125,663,016 (GRCm38)	Y1119*	probably null	Het
Hgd	A	T	16: 37,588,685 (GRCm38)		probably benign	Het
Ildr2	G	T	1: 166,308,899 (GRCm38)	V436L	probably benign	Het
Intu	G	A	3: 40,675,305 (GRCm38)	C355Y	probably damaging	Het
Irf2bpl	G	T	12: 86,883,096 (GRCm38)	P268T	probably benign	Het
Jarid2	T	C	13: 44,840,882 (GRCm38)		probably null	Het
Jup	A	T	11: 100,372,401 (GRCm38)	M716K	probably benign	Het
Kank1	G	A	19: 25,411,473 (GRCm38)	V809I	probably damaging	Het
Kdm1b	T	A	13: 47,064,244 (GRCm38)		probably benign	Het
Kdm3a	C	T	6: 71,600,755 (GRCm38)	C687Y	probably damaging	Het
Kdm5d	T	A	Y: 942,437 (GRCm38)		probably benign	Het
Kifap3	T	A	1: 163,865,552 (GRCm38)		probably benign	Het
Macf1	T	A	4: 123,483,660 (GRCm38)	K1400*	probably null	Het
Majin	A	G	19: 6,212,117 (GRCm38)		probably benign	Het
Mb21d1	G	A	9: 78,435,738 (GRCm38)		probably benign	Het
Mctp1	A	G	13: 77,020,821 (GRCm38)	I846V	probably benign	Het
Mrgpra2b	T	A	7: 47,464,127 (GRCm38)	I286F	possibly damaging	Het
Neil3	T	G	8: 53,609,396 (GRCm38)		probably benign	Het
Nox3	G	T	17: 3,695,563 (GRCm38)	N23K	probably damaging	Het
Nt5c3	T	C	6: 56,883,812 (GRCm38)	K219E	probably benign	Het
Olfr1458	G	A	19: 13,103,278 (GRCm38)	R3C	possibly damaging	Het
Olfr213	A	T	6: 116,540,485 (GRCm38)	N11Y	probably damaging	Het
Olfr389	T	A	11: 73,776,437 (GRCm38)	M297L	probably benign	Het
Olfr524	A	C	7: 140,202,116 (GRCm38)	F218C	possibly damaging	Het
Olfr548-ps1	T	A	7: 102,542,686 (GRCm38)	I250N	probably damaging	Het
Olfr954	T	C	9: 39,461,593 (GRCm38)	L54P	probably damaging	Het
Pacsin2	A	G	15: 83,379,795 (GRCm38)	V347A	possibly damaging	Het
Pcdhb7	A	T	18: 37,342,804 (GRCm38)	E331V	probably damaging	Het
Pcid2	A	C	8: 13,081,262 (GRCm38)		probably null	Het
Pcsk9	T	C	4: 106,450,077 (GRCm38)	D323G	possibly damaging	Het
Pdhb	T	C	14: 8,169,801 (GRCm38)	E203G	probably damaging	Het
Phlpp2	A	G	8: 109,928,463 (GRCm38)	Y630C	probably benign	Het
Pidd1	C	T	7: 141,439,133 (GRCm38)	A812T	probably damaging	Het
Plau	G	A	14: 20,842,314 (GRCm38)	R389H	probably benign	Het
Plekhg6	G	A	6: 125,364,629 (GRCm38)		probably null	Het
Ppox	T	C	1: 171,277,749 (GRCm38)	Y321C	probably damaging	Het
Pxdn	A	G	12: 29,987,066 (GRCm38)	N281S	possibly damaging	Het
Pycrl	A	T	15: 75,918,388 (GRCm38)	M138K	probably benign	Het
Radil	T	C	5: 142,497,873 (GRCm38)	Y526C	probably damaging	Het
Ranbp3	C	A	17: 56,707,169 (GRCm38)	D233E	probably benign	Het
Rhpn1	A	G	15: 75,711,872 (GRCm38)	Q402R	possibly damaging	Het
Sec23b	T	A	2: 144,568,612 (GRCm38)		probably benign	Het
Sel1l2	A	T	2: 140,240,912 (GRCm38)	L602*	probably null	Het
Sema5b	G	A	16: 35,646,355 (GRCm38)	G209D	probably damaging	Het
Svep1	T	C	4: 58,073,333 (GRCm38)	Y1992C	possibly damaging	Het
Syncrip	T	A	9: 88,456,259 (GRCm38)		probably benign	Het
Synj1	G	T	16: 90,967,354 (GRCm38)	A65E	probably damaging	Het
Taar2	G	A	10: 23,941,495 (GRCm38)	R311H	probably benign	Het
Tecrl	T	C	5: 83,354,763 (GRCm38)		probably benign	Het
Tenm4	G	T	7: 96,777,851 (GRCm38)	G698C	probably damaging	Het
Tmem209	G	A	6: 30,491,182 (GRCm38)	L259F	probably damaging	Het
Tmem247	G	A	17: 86,918,503 (GRCm38)	E124K	possibly damaging	Het
Tnks2	C	A	19: 36,852,821 (GRCm38)	A218E	probably damaging	Het
Tppp	T	A	13: 74,021,311 (GRCm38)	F57I	probably damaging	Het
Trim36	A	G	18: 46,172,525 (GRCm38)	W452R	probably damaging	Het
Vars2	A	T	17: 35,664,584 (GRCm38)	V262E	probably damaging	Het
Vmn2r92	C	T	17: 18,167,957 (GRCm38)	A408V	probably damaging	Het
Zfp516	G	T	18: 82,955,772 (GRCm38)	A32S	probably benign	Het
Zfy2	G	T	Y: 2,107,348 (GRCm38)	L429I	possibly damaging	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,938,905 (GRCm38)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,951,597 (GRCm38)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	120,022,941 (GRCm38)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,926,564 (GRCm38)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,967,720 (GRCm38)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,965,530 (GRCm38)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,943,575 (GRCm38)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,951,651 (GRCm38)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,951,214 (GRCm38)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	120,029,054 (GRCm38)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,951,271 (GRCm38)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,967,579 (GRCm38)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,950,992 (GRCm38)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,966,247 (GRCm38)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,938,914 (GRCm38)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,937,023 (GRCm38)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,965,497 (GRCm38)	missense	probably benign
IGL03404:Dnah3	APN	7	119,938,977 (GRCm38)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,952,739 (GRCm38)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	120,078,402 (GRCm38)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,950,651 (GRCm38)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	120,019,701 (GRCm38)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	120,077,775 (GRCm38)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,922,730 (GRCm38)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,922,730 (GRCm38)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	120,045,659 (GRCm38)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,965,659 (GRCm38)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	120,086,720 (GRCm38)	missense	possibly damaging	0.91
R0525:Dnah3	UTSW	7	119,928,754 (GRCm38)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	120,071,887 (GRCm38)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	120,020,915 (GRCm38)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,967,905 (GRCm38)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	120,030,051 (GRCm38)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,952,739 (GRCm38)	splice site	probably benign
R0972:Dnah3	UTSW	7	120,035,340 (GRCm38)	splice site	probably null
R1066:Dnah3	UTSW	7	120,061,009 (GRCm38)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	120,078,445 (GRCm38)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,923,030 (GRCm38)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,939,004 (GRCm38)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	120,090,676 (GRCm38)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,951,979 (GRCm38)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	120,047,630 (GRCm38)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	120,070,958 (GRCm38)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	120,089,946 (GRCm38)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	120,019,695 (GRCm38)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,926,449 (GRCm38)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,971,179 (GRCm38)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,928,740 (GRCm38)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	120,045,786 (GRCm38)	splice site	probably null
R1711:Dnah3	UTSW	7	120,078,571 (GRCm38)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	120,035,359 (GRCm38)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	120,078,402 (GRCm38)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,928,856 (GRCm38)	splice site	probably null
R1883:Dnah3	UTSW	7	120,077,919 (GRCm38)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	120,086,334 (GRCm38)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,975,129 (GRCm38)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,967,959 (GRCm38)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,967,570 (GRCm38)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	120,095,177 (GRCm38)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,951,242 (GRCm38)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	120,039,406 (GRCm38)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,951,909 (GRCm38)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,967,759 (GRCm38)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,952,013 (GRCm38)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,951,569 (GRCm38)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,975,129 (GRCm38)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	120,045,788 (GRCm38)	splice site	probably null
R2567:Dnah3	UTSW	7	119,952,697 (GRCm38)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,967,938 (GRCm38)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,951,499 (GRCm38)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,951,115 (GRCm38)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,951,110 (GRCm38)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	120,078,481 (GRCm38)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,951,080 (GRCm38)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	120,086,720 (GRCm38)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	120,083,293 (GRCm38)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	120,029,025 (GRCm38)	nonsense	probably null
R4478:Dnah3	UTSW	7	120,071,863 (GRCm38)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	120,009,331 (GRCm38)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	120,089,946 (GRCm38)	missense	probably benign
R4649:Dnah3	UTSW	7	120,047,698 (GRCm38)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,950,651 (GRCm38)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	120,059,366 (GRCm38)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	120,077,946 (GRCm38)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	120,079,406 (GRCm38)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,967,824 (GRCm38)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	120,011,072 (GRCm38)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,951,681 (GRCm38)	nonsense	probably null
R4935:Dnah3	UTSW	7	120,016,477 (GRCm38)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,931,560 (GRCm38)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,956,201 (GRCm38)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,928,779 (GRCm38)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	120,071,905 (GRCm38)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,951,580 (GRCm38)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	120,020,946 (GRCm38)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	120,032,790 (GRCm38)	missense	probably benign
R5069:Dnah3	UTSW	7	120,032,790 (GRCm38)	missense	probably benign
R5154:Dnah3	UTSW	7	119,952,419 (GRCm38)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	120,032,638 (GRCm38)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	120,021,011 (GRCm38)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,943,648 (GRCm38)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,924,903 (GRCm38)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	120,090,076 (GRCm38)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,971,466 (GRCm38)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,971,621 (GRCm38)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,939,065 (GRCm38)	splice site	probably null
R5673:Dnah3	UTSW	7	119,951,589 (GRCm38)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	120,077,851 (GRCm38)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	120,059,198 (GRCm38)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,978,222 (GRCm38)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	120,089,952 (GRCm38)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,943,599 (GRCm38)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,931,473 (GRCm38)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	120,039,362 (GRCm38)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,938,833 (GRCm38)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,975,108 (GRCm38)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	120,069,704 (GRCm38)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	120,078,501 (GRCm38)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	120,016,526 (GRCm38)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,922,880 (GRCm38)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	120,073,541 (GRCm38)	missense	probably benign
R6004:Dnah3	UTSW	7	120,086,297 (GRCm38)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	120,071,647 (GRCm38)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	120,071,647 (GRCm38)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,967,522 (GRCm38)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	120,030,031 (GRCm38)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	120,086,246 (GRCm38)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,965,488 (GRCm38)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	120,009,384 (GRCm38)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	120,054,633 (GRCm38)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,922,968 (GRCm38)	splice site	probably null
R6447:Dnah3	UTSW	7	119,923,054 (GRCm38)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	120,060,956 (GRCm38)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	120,070,949 (GRCm38)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,922,974 (GRCm38)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,971,727 (GRCm38)	missense	probably benign
R6882:Dnah3	UTSW	7	119,971,184 (GRCm38)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	120,054,601 (GRCm38)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	120,032,754 (GRCm38)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	120,030,010 (GRCm38)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,971,089 (GRCm38)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,922,742 (GRCm38)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	120,071,523 (GRCm38)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	120,032,670 (GRCm38)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,943,633 (GRCm38)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,981,344 (GRCm38)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	120,029,985 (GRCm38)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	120,029,016 (GRCm38)	missense	probably benign
R7375:Dnah3	UTSW	7	119,951,677 (GRCm38)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	120,060,960 (GRCm38)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,966,251 (GRCm38)	missense
R7431:Dnah3	UTSW	7	120,051,744 (GRCm38)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	120,060,912 (GRCm38)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	120,073,592 (GRCm38)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,971,594 (GRCm38)	missense	probably benign
R7618:Dnah3	UTSW	7	119,978,378 (GRCm38)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,967,434 (GRCm38)	missense
R7728:Dnah3	UTSW	7	119,938,828 (GRCm38)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,971,215 (GRCm38)	splice site	probably null
R7757:Dnah3	UTSW	7	120,071,570 (GRCm38)	missense	probably benign
R7774:Dnah3	UTSW	7	119,951,752 (GRCm38)	nonsense	probably null
R7804:Dnah3	UTSW	7	120,011,012 (GRCm38)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,952,618 (GRCm38)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,951,704 (GRCm38)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,967,552 (GRCm38)	missense
R7903:Dnah3	UTSW	7	120,042,128 (GRCm38)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	120,077,789 (GRCm38)	missense	probably benign
R8142:Dnah3	UTSW	7	120,060,966 (GRCm38)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,967,614 (GRCm38)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,926,413 (GRCm38)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,951,152 (GRCm38)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	120,071,881 (GRCm38)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,952,208 (GRCm38)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,952,505 (GRCm38)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	120,011,030 (GRCm38)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,952,208 (GRCm38)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,937,030 (GRCm38)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,951,368 (GRCm38)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,962,152 (GRCm38)	missense
R8912:Dnah3	UTSW	7	120,090,646 (GRCm38)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,950,658 (GRCm38)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,937,071 (GRCm38)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,952,049 (GRCm38)	missense	probably benign
R9053:Dnah3	UTSW	7	120,019,764 (GRCm38)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	120,085,145 (GRCm38)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	120,085,128 (GRCm38)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,967,636 (GRCm38)	missense
R9383:Dnah3	UTSW	7	120,047,596 (GRCm38)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	120,028,982 (GRCm38)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,952,250 (GRCm38)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,952,300 (GRCm38)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	120,045,689 (GRCm38)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	120,051,728 (GRCm38)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	120,010,891 (GRCm38)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	120,010,891 (GRCm38)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	120,071,013 (GRCm38)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,962,133 (GRCm38)	missense
R9633:Dnah3	UTSW	7	119,950,993 (GRCm38)	missense	probably benign
R9654:Dnah3	UTSW	7	120,042,173 (GRCm38)	nonsense	probably null
R9665:Dnah3	UTSW	7	120,045,758 (GRCm38)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	120,078,388 (GRCm38)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,975,076 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	120,010,873 (GRCm38)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	120,086,297 (GRCm38)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,967,803 (GRCm38)	missense
Z1177:Dnah3	UTSW	7	120,007,862 (GRCm38)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,967,901 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- ATGCTGAAGACCTTGACCTGGTCC -3'
(R):5'- ACCACGACAACGATGATAACGATGATG -3'

Sequencing Primer
(F):5'- GTTCTCAGGGACAATCACCT -3'
(R):5'- aacgatgataacgatgatgatgac -3'

Posted On

2013-05-23