Incidental Mutation 'R5074:Cfap65'
| ID |
386781 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap65
|
| Ensembl Gene |
ENSMUSG00000047021 |
| Gene Name |
cilia and flagella associated protein 65 |
| Synonyms |
Ccdc108, B230363K08Rik |
| MMRRC Submission |
042663-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.676)
|
| Stock # |
R5074 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
74902071-74935599 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 74922978 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 695
(S695T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092440
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094844]
|
| AlphaFold |
Q3V0B4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094844
AA Change: S695T
PolyPhen 2
Score 0.042 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000092440
Gene: ENSMUSG00000047021
AA Change: S695T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
111 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
745 |
890 |
9.31e-5 |
PROSPERO |
|
internal_repeat_1
|
1167 |
1322 |
9.31e-5 |
PROSPERO |
|
low complexity region
|
1350 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1592 |
N/A |
INTRINSIC |
|
coiled coil region
|
1687 |
1724 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000130489
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139950
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
A |
T |
3: 124,416,833 (GRCm38) |
H143Q |
probably benign |
Het |
| Abca3 |
C |
T |
17: 24,374,300 (GRCm38) |
R224C |
probably damaging |
Het |
| Adcy8 |
A |
T |
15: 64,787,358 (GRCm38) |
W528R |
probably damaging |
Het |
| Agbl1 |
A |
G |
7: 76,421,917 (GRCm38) |
E329G |
probably damaging |
Het |
| Agbl5 |
G |
A |
5: 30,903,059 (GRCm38) |
R141Q |
probably damaging |
Het |
| Ampd2 |
A |
T |
3: 108,079,233 (GRCm38) |
M245K |
probably damaging |
Het |
| Apob |
G |
A |
12: 8,005,219 (GRCm38) |
|
probably null |
Het |
| Apool |
C |
T |
X: 112,349,843 (GRCm38) |
Q60* |
probably null |
Het |
| Aqp1 |
A |
T |
6: 55,345,535 (GRCm38) |
I172F |
probably damaging |
Het |
| Atp7a |
A |
G |
X: 106,109,768 (GRCm38) |
D1092G |
probably benign |
Het |
| Ccdc83 |
A |
T |
7: 90,250,529 (GRCm38) |
F45Y |
probably damaging |
Het |
| Cct8l1 |
G |
A |
5: 25,516,883 (GRCm38) |
V199I |
probably benign |
Het |
| Cdc23 |
C |
A |
18: 34,651,689 (GRCm38) |
V7L |
unknown |
Het |
| Cdc25a |
T |
A |
9: 109,884,140 (GRCm38) |
C227S |
possibly damaging |
Het |
| Ces1a |
A |
G |
8: 93,032,675 (GRCm38) |
S278P |
possibly damaging |
Het |
| Col13a1 |
A |
G |
10: 61,874,018 (GRCm38) |
|
silent |
Het |
| Ctps1 |
A |
T |
4: 120,553,973 (GRCm38) |
L282Q |
probably damaging |
Het |
| Cyp2a22 |
A |
T |
7: 26,932,481 (GRCm38) |
F450Y |
probably benign |
Het |
| Cyp2d10 |
C |
T |
15: 82,403,753 (GRCm38) |
R383H |
probably benign |
Het |
| Dennd3 |
G |
A |
15: 73,547,295 (GRCm38) |
R645H |
probably damaging |
Het |
| Dnaaf5 |
G |
T |
5: 139,174,207 (GRCm38) |
R620L |
probably damaging |
Het |
| Dnah11 |
A |
T |
12: 118,082,453 (GRCm38) |
L1750* |
probably null |
Het |
| Dnah9 |
A |
G |
11: 65,850,040 (GRCm38) |
F4107L |
probably damaging |
Het |
| Dnaja3 |
A |
T |
16: 4,696,425 (GRCm38) |
T274S |
probably damaging |
Het |
| Dot1l |
A |
G |
10: 80,784,646 (GRCm38) |
D514G |
possibly damaging |
Het |
| Dst |
A |
C |
1: 34,295,263 (GRCm38) |
K4857N |
probably damaging |
Het |
| Dysf |
A |
T |
6: 84,137,272 (GRCm38) |
K1226M |
probably damaging |
Het |
| Enpep |
T |
A |
3: 129,303,755 (GRCm38) |
Q409L |
probably damaging |
Het |
| Fign |
A |
T |
2: 63,979,693 (GRCm38) |
L411* |
probably null |
Het |
| Flt1 |
C |
A |
5: 147,683,939 (GRCm38) |
A132S |
probably benign |
Het |
| Fryl |
G |
A |
5: 73,074,767 (GRCm38) |
P1550L |
probably damaging |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,430,958 (GRCm38) |
|
probably benign |
Het |
| H2ab3 |
T |
C |
X: 120,312,846 (GRCm38) |
T84A |
probably damaging |
Het |
| Hal |
A |
T |
10: 93,514,042 (GRCm38) |
I555F |
probably damaging |
Het |
| Hibadh |
C |
T |
6: 52,620,094 (GRCm38) |
V122M |
possibly damaging |
Het |
| Hsd3b3 |
T |
C |
3: 98,742,024 (GRCm38) |
T328A |
possibly damaging |
Het |
| Ifi44 |
T |
C |
3: 151,749,632 (GRCm38) |
|
probably benign |
Het |
| Ifi47 |
A |
G |
11: 49,095,534 (GRCm38) |
T43A |
probably benign |
Het |
| Inf2 |
A |
T |
12: 112,612,039 (GRCm38) |
|
probably null |
Het |
| Itga10 |
C |
T |
3: 96,652,211 (GRCm38) |
Q475* |
probably null |
Het |
| Itga6 |
T |
A |
2: 71,826,435 (GRCm38) |
D344E |
probably benign |
Het |
| Kcnmb4 |
T |
C |
10: 116,473,197 (GRCm38) |
T109A |
probably benign |
Het |
| Kif19a |
G |
A |
11: 114,767,227 (GRCm38) |
M37I |
probably benign |
Het |
| Kiss1r |
C |
A |
10: 79,918,762 (GRCm38) |
S30* |
probably null |
Het |
| Lrrc66 |
G |
A |
5: 73,608,011 (GRCm38) |
P563L |
probably damaging |
Het |
| Mamdc2 |
T |
C |
19: 23,378,796 (GRCm38) |
D96G |
probably benign |
Het |
| Map3k12 |
A |
T |
15: 102,501,832 (GRCm38) |
|
probably null |
Het |
| Mc3r |
A |
T |
2: 172,249,613 (GRCm38) |
I252F |
possibly damaging |
Het |
| Metrn |
C |
T |
17: 25,796,639 (GRCm38) |
G34D |
probably damaging |
Het |
| Mipep |
A |
G |
14: 60,809,013 (GRCm38) |
E328G |
probably benign |
Het |
| Mrtfa |
A |
G |
15: 81,022,426 (GRCm38) |
V91A |
probably damaging |
Het |
| Muc5b |
A |
T |
7: 141,859,262 (GRCm38) |
T1982S |
unknown |
Het |
| Myh8 |
A |
T |
11: 67,305,916 (GRCm38) |
T1792S |
possibly damaging |
Het |
| Myo1a |
T |
C |
10: 127,707,419 (GRCm38) |
|
probably null |
Het |
| Myo5a |
T |
A |
9: 75,174,156 (GRCm38) |
S1008T |
probably benign |
Het |
| Ncald |
A |
T |
15: 37,397,234 (GRCm38) |
H67Q |
probably damaging |
Het |
| Nudt5 |
T |
A |
2: 5,864,387 (GRCm38) |
H141Q |
probably benign |
Het |
| Numbl |
G |
A |
7: 27,280,990 (GRCm38) |
D466N |
probably damaging |
Het |
| Nup210 |
T |
A |
6: 91,055,327 (GRCm38) |
I20F |
probably benign |
Het |
| Odad1 |
T |
A |
7: 45,929,090 (GRCm38) |
M29K |
probably benign |
Het |
| Or10ak12 |
A |
C |
4: 118,808,860 (GRCm38) |
W319G |
possibly damaging |
Het |
| Or10p21 |
T |
C |
10: 129,011,344 (GRCm38) |
Y20H |
possibly damaging |
Het |
| Or14c46 |
A |
G |
7: 86,269,591 (GRCm38) |
I66T |
probably damaging |
Het |
| Or51l14 |
A |
T |
7: 103,451,410 (GRCm38) |
E24D |
probably benign |
Het |
| Or52e8b |
A |
T |
7: 105,024,053 (GRCm38) |
M309K |
probably benign |
Het |
| Or52n2c |
A |
C |
7: 104,925,493 (GRCm38) |
N90K |
probably benign |
Het |
| Or7h8 |
A |
T |
9: 20,212,582 (GRCm38) |
I78F |
possibly damaging |
Het |
| Or8h10 |
A |
T |
2: 86,978,322 (GRCm38) |
V158D |
possibly damaging |
Het |
| Papolg |
G |
A |
11: 23,867,331 (GRCm38) |
T153I |
possibly damaging |
Het |
| Pappa |
A |
G |
4: 65,205,128 (GRCm38) |
H900R |
probably benign |
Het |
| Pcdh17 |
T |
C |
14: 84,533,342 (GRCm38) |
S1087P |
probably benign |
Het |
| Phf11a |
T |
G |
14: 59,284,400 (GRCm38) |
L107F |
possibly damaging |
Het |
| Phlpp2 |
A |
T |
8: 109,925,829 (GRCm38) |
I602F |
probably damaging |
Het |
| Pik3c2g |
T |
A |
6: 139,720,147 (GRCm38) |
C65S |
probably null |
Het |
| Pilra |
A |
G |
5: 137,835,412 (GRCm38) |
F131L |
probably damaging |
Het |
| Pomt2 |
A |
C |
12: 87,133,460 (GRCm38) |
C256G |
probably damaging |
Het |
| Ppl |
A |
T |
16: 5,088,878 (GRCm38) |
S1184R |
probably benign |
Het |
| Prkaa1 |
G |
T |
15: 5,176,911 (GRCm38) |
R416L |
possibly damaging |
Het |
| Prkdc |
C |
A |
16: 15,772,048 (GRCm38) |
R2592S |
probably damaging |
Het |
| Prmt2 |
C |
T |
10: 76,222,556 (GRCm38) |
V140I |
probably damaging |
Het |
| Prodh |
A |
T |
16: 18,077,789 (GRCm38) |
|
probably null |
Het |
| Psg29 |
T |
A |
7: 17,211,838 (GRCm38) |
D444E |
probably damaging |
Het |
| Ptgs1 |
A |
T |
2: 36,251,260 (GRCm38) |
N573I |
probably damaging |
Het |
| Rbm38 |
C |
T |
2: 173,022,082 (GRCm38) |
P15S |
probably benign |
Het |
| Riox2 |
T |
C |
16: 59,491,873 (GRCm38) |
S458P |
possibly damaging |
Het |
| Rnase4 |
T |
C |
14: 51,105,245 (GRCm38) |
V142A |
possibly damaging |
Het |
| Rnf138 |
A |
G |
18: 21,026,147 (GRCm38) |
N244S |
probably benign |
Het |
| Rnf40 |
T |
C |
7: 127,597,286 (GRCm38) |
L802P |
probably damaging |
Het |
| Sfxn4 |
C |
T |
19: 60,851,012 (GRCm38) |
V203M |
probably damaging |
Het |
| Skor2 |
G |
T |
18: 76,858,954 (GRCm38) |
E124* |
probably null |
Het |
| Slc4a2 |
G |
A |
5: 24,438,762 (GRCm38) |
S855N |
probably benign |
Het |
| Slc8a2 |
T |
C |
7: 16,150,583 (GRCm38) |
L626P |
possibly damaging |
Het |
| Slco4c1 |
G |
A |
1: 96,841,228 (GRCm38) |
P303L |
probably damaging |
Het |
| Slirp |
A |
G |
12: 87,444,014 (GRCm38) |
T29A |
probably damaging |
Het |
| Snrpd3 |
G |
T |
10: 75,519,393 (GRCm38) |
C20F |
possibly damaging |
Het |
| Spag17 |
T |
A |
3: 100,080,118 (GRCm38) |
Y1575N |
possibly damaging |
Het |
| St8sia4 |
G |
A |
1: 95,667,185 (GRCm38) |
A26V |
probably benign |
Het |
| Stab2 |
A |
T |
10: 86,863,558 (GRCm38) |
I481N |
probably benign |
Het |
| Tenm2 |
T |
A |
11: 36,068,381 (GRCm38) |
T1114S |
probably damaging |
Het |
| Tgm1 |
A |
G |
14: 55,709,935 (GRCm38) |
V323A |
probably damaging |
Het |
| Tmco4 |
A |
G |
4: 139,058,122 (GRCm38) |
H501R |
probably damaging |
Het |
| Tob1 |
A |
T |
11: 94,213,741 (GRCm38) |
R34S |
possibly damaging |
Het |
| Trhr2 |
C |
T |
8: 122,357,371 (GRCm38) |
V297I |
probably benign |
Het |
| Trim30d |
A |
C |
7: 104,487,958 (GRCm38) |
V13G |
probably damaging |
Het |
| Trpm3 |
T |
C |
19: 22,885,349 (GRCm38) |
V485A |
possibly damaging |
Het |
| Trrap |
T |
C |
5: 144,851,179 (GRCm38) |
I3518T |
probably damaging |
Het |
| Ttc27 |
T |
C |
17: 74,747,755 (GRCm38) |
L352P |
probably damaging |
Het |
| Ush1g |
A |
G |
11: 115,318,297 (GRCm38) |
L357P |
possibly damaging |
Het |
| Usp24 |
A |
G |
4: 106,420,447 (GRCm38) |
H2258R |
probably benign |
Het |
| Vcam1 |
A |
G |
3: 116,124,388 (GRCm38) |
V308A |
probably damaging |
Het |
| Vdr |
A |
G |
15: 97,857,578 (GRCm38) |
S355P |
probably benign |
Het |
| Vldlr |
T |
C |
19: 27,238,277 (GRCm38) |
S184P |
probably damaging |
Het |
| Xpo4 |
C |
A |
14: 57,584,641 (GRCm38) |
A1073S |
probably benign |
Het |
| Zfand2b |
A |
G |
1: 75,170,990 (GRCm38) |
D224G |
probably benign |
Het |
| Zfp263 |
A |
G |
16: 3,746,840 (GRCm38) |
R240G |
possibly damaging |
Het |
|
| Other mutations in Cfap65 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01107:Cfap65
|
APN |
1 |
74,919,183 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01526:Cfap65
|
APN |
1 |
74,911,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01716:Cfap65
|
APN |
1 |
74,927,194 (GRCm38) |
missense |
probably benign |
|
|
IGL01780:Cfap65
|
APN |
1 |
74,928,348 (GRCm38) |
nonsense |
probably null |
|
|
IGL01993:Cfap65
|
APN |
1 |
74,920,543 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02164:Cfap65
|
APN |
1 |
74,928,145 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
IGL02350:Cfap65
|
APN |
1 |
74,928,348 (GRCm38) |
nonsense |
probably null |
|
|
IGL02357:Cfap65
|
APN |
1 |
74,928,348 (GRCm38) |
nonsense |
probably null |
|
|
IGL02576:Cfap65
|
APN |
1 |
74,903,458 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02756:Cfap65
|
APN |
1 |
74,905,080 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02792:Cfap65
|
APN |
1 |
74,927,178 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02874:Cfap65
|
APN |
1 |
74,911,108 (GRCm38) |
nonsense |
probably null |
|
|
IGL03101:Cfap65
|
APN |
1 |
74,928,433 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03348:Cfap65
|
APN |
1 |
74,927,619 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03396:Cfap65
|
APN |
1 |
74,904,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4131001:Cfap65
|
UTSW |
1 |
74,928,342 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0077:Cfap65
|
UTSW |
1 |
74,931,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0227:Cfap65
|
UTSW |
1 |
74,931,958 (GRCm38) |
nonsense |
probably null |
|
|
R0281:Cfap65
|
UTSW |
1 |
74,927,071 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0312:Cfap65
|
UTSW |
1 |
74,904,067 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,929,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,929,301 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0347:Cfap65
|
UTSW |
1 |
74,926,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0359:Cfap65
|
UTSW |
1 |
74,920,601 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0361:Cfap65
|
UTSW |
1 |
74,925,440 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0465:Cfap65
|
UTSW |
1 |
74,916,884 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0549:Cfap65
|
UTSW |
1 |
74,918,444 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0646:Cfap65
|
UTSW |
1 |
74,902,169 (GRCm38) |
missense |
probably benign |
0.09 |
|
R0734:Cfap65
|
UTSW |
1 |
74,918,887 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0763:Cfap65
|
UTSW |
1 |
74,904,682 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0990:Cfap65
|
UTSW |
1 |
74,921,519 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R1079:Cfap65
|
UTSW |
1 |
74,905,713 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1079:Cfap65
|
UTSW |
1 |
74,902,447 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1083:Cfap65
|
UTSW |
1 |
74,918,504 (GRCm38) |
splice site |
probably benign |
|
|
R1159:Cfap65
|
UTSW |
1 |
74,929,340 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1282:Cfap65
|
UTSW |
1 |
74,925,104 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1644:Cfap65
|
UTSW |
1 |
74,917,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1796:Cfap65
|
UTSW |
1 |
74,918,948 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1950:Cfap65
|
UTSW |
1 |
74,907,660 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2079:Cfap65
|
UTSW |
1 |
74,917,199 (GRCm38) |
missense |
probably benign |
0.30 |
|
R2132:Cfap65
|
UTSW |
1 |
74,907,691 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2136:Cfap65
|
UTSW |
1 |
74,917,273 (GRCm38) |
frame shift |
probably null |
|
|
R2219:Cfap65
|
UTSW |
1 |
74,904,025 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2220:Cfap65
|
UTSW |
1 |
74,904,025 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2291:Cfap65
|
UTSW |
1 |
74,926,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2417:Cfap65
|
UTSW |
1 |
74,927,186 (GRCm38) |
small insertion |
probably benign |
|
|
R3114:Cfap65
|
UTSW |
1 |
74,927,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4202:Cfap65
|
UTSW |
1 |
74,920,542 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4214:Cfap65
|
UTSW |
1 |
74,927,681 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4254:Cfap65
|
UTSW |
1 |
74,903,358 (GRCm38) |
missense |
probably benign |
0.17 |
|
R4547:Cfap65
|
UTSW |
1 |
74,907,612 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4548:Cfap65
|
UTSW |
1 |
74,907,612 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4588:Cfap65
|
UTSW |
1 |
74,904,056 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4657:Cfap65
|
UTSW |
1 |
74,925,354 (GRCm38) |
intron |
probably benign |
|
|
R4701:Cfap65
|
UTSW |
1 |
74,918,908 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4755:Cfap65
|
UTSW |
1 |
74,928,361 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4820:Cfap65
|
UTSW |
1 |
74,927,632 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4831:Cfap65
|
UTSW |
1 |
74,917,295 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4866:Cfap65
|
UTSW |
1 |
74,925,557 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4869:Cfap65
|
UTSW |
1 |
74,919,261 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4881:Cfap65
|
UTSW |
1 |
74,907,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4884:Cfap65
|
UTSW |
1 |
74,903,124 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4950:Cfap65
|
UTSW |
1 |
74,906,336 (GRCm38) |
nonsense |
probably null |
|
|
R5083:Cfap65
|
UTSW |
1 |
74,906,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5164:Cfap65
|
UTSW |
1 |
74,926,516 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5268:Cfap65
|
UTSW |
1 |
74,924,902 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5333:Cfap65
|
UTSW |
1 |
74,903,175 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5417:Cfap65
|
UTSW |
1 |
74,925,100 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5582:Cfap65
|
UTSW |
1 |
74,907,518 (GRCm38) |
intron |
probably benign |
|
|
R5669:Cfap65
|
UTSW |
1 |
74,924,968 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6010:Cfap65
|
UTSW |
1 |
74,923,031 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6084:Cfap65
|
UTSW |
1 |
74,920,405 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6112:Cfap65
|
UTSW |
1 |
74,903,139 (GRCm38) |
missense |
probably benign |
0.14 |
|
R6425:Cfap65
|
UTSW |
1 |
74,927,709 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6677:Cfap65
|
UTSW |
1 |
74,904,685 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6693:Cfap65
|
UTSW |
1 |
74,917,286 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6838:Cfap65
|
UTSW |
1 |
74,932,021 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6861:Cfap65
|
UTSW |
1 |
74,925,115 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6958:Cfap65
|
UTSW |
1 |
74,931,899 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R7134:Cfap65
|
UTSW |
1 |
74,926,633 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7320:Cfap65
|
UTSW |
1 |
74,926,604 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7340:Cfap65
|
UTSW |
1 |
74,921,583 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7426:Cfap65
|
UTSW |
1 |
74,920,426 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7529:Cfap65
|
UTSW |
1 |
74,926,610 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7634:Cfap65
|
UTSW |
1 |
74,902,434 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7654:Cfap65
|
UTSW |
1 |
74,933,144 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7704:Cfap65
|
UTSW |
1 |
74,928,368 (GRCm38) |
missense |
probably benign |
0.19 |
|
R7727:Cfap65
|
UTSW |
1 |
74,926,625 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7895:Cfap65
|
UTSW |
1 |
74,933,162 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8215:Cfap65
|
UTSW |
1 |
74,910,743 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8344:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8345:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8413:Cfap65
|
UTSW |
1 |
74,917,169 (GRCm38) |
nonsense |
probably null |
|
|
R8431:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8432:Cfap65
|
UTSW |
1 |
74,928,044 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8528:Cfap65
|
UTSW |
1 |
74,905,937 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R8809:Cfap65
|
UTSW |
1 |
74,903,223 (GRCm38) |
missense |
probably benign |
0.43 |
|
R8996:Cfap65
|
UTSW |
1 |
74,902,188 (GRCm38) |
missense |
probably benign |
0.11 |
|
R9020:Cfap65
|
UTSW |
1 |
74,920,393 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9043:Cfap65
|
UTSW |
1 |
74,904,688 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R9127:Cfap65
|
UTSW |
1 |
74,919,351 (GRCm38) |
splice site |
probably benign |
|
|
R9187:Cfap65
|
UTSW |
1 |
74,917,358 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9210:Cfap65
|
UTSW |
1 |
74,920,408 (GRCm38) |
missense |
probably benign |
|
|
R9212:Cfap65
|
UTSW |
1 |
74,920,408 (GRCm38) |
missense |
probably benign |
|
|
R9273:Cfap65
|
UTSW |
1 |
74,921,610 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9454:Cfap65
|
UTSW |
1 |
74,905,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9514:Cfap65
|
UTSW |
1 |
74,906,309 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9595:Cfap65
|
UTSW |
1 |
74,907,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9721:Cfap65
|
UTSW |
1 |
74,919,342 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9742:Cfap65
|
UTSW |
1 |
74,904,681 (GRCm38) |
missense |
probably benign |
0.08 |
|
RF009:Cfap65
|
UTSW |
1 |
74,905,647 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Cfap65
|
UTSW |
1 |
74,910,747 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGGGAGACACATGATCCAC -3'
(R):5'- TAGGATACCTCCAGCACAGG -3'
Sequencing Primer
(F):5'- TGGCCTAAATCCCCAGGATG -3'
(R):5'- GCACAGGGCTAGGGAGG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation