Incidental Mutation 'R0426:Synj1'
| ID |
38689 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Synj1
|
| Ensembl Gene |
ENSMUSG00000022973 |
| Gene Name |
synaptojanin 1 |
| Synonyms |
A930006D20Rik |
| MMRRC Submission |
038628-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0426 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
90732980-90808196 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 90764242 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Glutamic Acid
at position 65
(A65E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156148
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000121759]
[ENSMUST00000130813]
[ENSMUST00000170853]
[ENSMUST00000231472]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000118246
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000118390
AA Change: A600E
|
| SMART Domains |
Protein: ENSMUSP00000113518
Gene: ENSMUSG00000022973
AA Change: A600E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
1 |
15 |
N/A |
INTRINSIC |
|
Pfam:Syja_N
|
75 |
356 |
3.1e-71 |
PFAM |
|
IPPc
|
546 |
889 |
6.37e-177 |
SMART |
|
DUF1866
|
882 |
1024 |
1.24e-80 |
SMART |
|
low complexity region
|
1040 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1117 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1155 |
1166 |
N/A |
INTRINSIC |
|
low complexity region
|
1189 |
1208 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1322 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000121759
AA Change: A626E
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000113308
Gene: ENSMUSG00000022973
AA Change: A626E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
9 |
40 |
N/A |
INTRINSIC |
|
Pfam:Syja_N
|
100 |
381 |
4.2e-71 |
PFAM |
|
IPPc
|
571 |
914 |
6.37e-177 |
SMART |
|
DUF1866
|
907 |
1049 |
1.24e-80 |
SMART |
|
low complexity region
|
1065 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1142 |
1176 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1214 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1314 |
1343 |
N/A |
INTRINSIC |
|
Blast:IPPc
|
1344 |
1428 |
1e-17 |
BLAST |
|
low complexity region
|
1564 |
1596 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000130813
AA Change: A581E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000119712
Gene: ENSMUSG00000022973
AA Change: A581E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Syja_N
|
59 |
346 |
1.4e-86 |
PFAM |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
IPPc
|
526 |
693 |
1.8e-9 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170853
AA Change: A586E
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000128997
Gene: ENSMUSG00000022973
AA Change: A586E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Syja_N
|
59 |
346 |
1.7e-85 |
PFAM |
|
IPPc
|
531 |
874 |
6.37e-177 |
SMART |
|
DUF1866
|
867 |
1009 |
1.24e-80 |
SMART |
|
low complexity region
|
1025 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1140 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1174 |
1193 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1307 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000231472
AA Change: A65E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Meta Mutation Damage Score |
0.9439 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.9%
|
| Validation Efficiency |
96% (86/90) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit neurological defects associated with impaired phosphoinositide metabolism and accumulation of clathrin-coated vesicles at nerve endings. Mutants show impaired suckling and most die within 24 hours of birth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
G |
T |
11: 109,845,853 (GRCm39) |
|
probably benign |
Het |
| Acadl |
A |
T |
1: 66,880,805 (GRCm39) |
F320L |
probably damaging |
Het |
| Acsbg1 |
T |
C |
9: 54,530,030 (GRCm39) |
D222G |
probably benign |
Het |
| Anapc15 |
A |
G |
7: 101,547,240 (GRCm39) |
T39A |
probably benign |
Het |
| Ano3 |
A |
T |
2: 110,491,519 (GRCm39) |
V919E |
probably damaging |
Het |
| Arhgef12 |
T |
C |
9: 42,882,286 (GRCm39) |
|
probably null |
Het |
| Atad5 |
T |
A |
11: 80,003,658 (GRCm39) |
I1091N |
probably benign |
Het |
| Atf1 |
A |
T |
15: 100,130,708 (GRCm39) |
H26L |
possibly damaging |
Het |
| Atp10a |
T |
C |
7: 58,434,482 (GRCm39) |
M252T |
probably benign |
Het |
| Btbd8 |
C |
T |
5: 107,658,239 (GRCm39) |
T1603I |
probably damaging |
Het |
| Cd55 |
C |
T |
1: 130,376,109 (GRCm39) |
R347H |
probably benign |
Het |
| Cdc27 |
A |
C |
11: 104,403,853 (GRCm39) |
|
probably null |
Het |
| Cdh9 |
G |
A |
15: 16,823,540 (GRCm39) |
|
probably null |
Het |
| Cdk11b |
T |
C |
4: 155,726,969 (GRCm39) |
|
probably benign |
Het |
| Cep70 |
A |
G |
9: 99,179,737 (GRCm39) |
D567G |
probably benign |
Het |
| Cep78 |
A |
T |
19: 15,948,334 (GRCm39) |
Y382* |
probably null |
Het |
| Cgas |
G |
A |
9: 78,343,020 (GRCm39) |
|
probably benign |
Het |
| Col9a2 |
T |
C |
4: 120,901,857 (GRCm39) |
|
probably benign |
Het |
| Cyp2d12 |
G |
A |
15: 82,443,164 (GRCm39) |
D409N |
probably benign |
Het |
| Ddx39a |
A |
G |
8: 84,448,398 (GRCm39) |
T217A |
probably benign |
Het |
| Dennd1b |
T |
A |
1: 139,097,934 (GRCm39) |
D733E |
probably benign |
Het |
| Dicer1 |
A |
G |
12: 104,668,801 (GRCm39) |
S1294P |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 119,542,795 (GRCm39) |
E3539G |
probably benign |
Het |
| Dnmbp |
A |
G |
19: 43,840,875 (GRCm39) |
|
probably benign |
Het |
| Dysf |
T |
C |
6: 84,126,739 (GRCm39) |
L1332P |
probably damaging |
Het |
| F5 |
A |
G |
1: 164,010,409 (GRCm39) |
D380G |
probably damaging |
Het |
| Fam171a1 |
T |
C |
2: 3,226,433 (GRCm39) |
V522A |
probably benign |
Het |
| Fhip1b |
A |
C |
7: 105,038,680 (GRCm39) |
C186W |
probably damaging |
Het |
| Galr2 |
C |
A |
11: 116,172,517 (GRCm39) |
A69D |
probably damaging |
Het |
| Grk2 |
T |
C |
19: 4,340,628 (GRCm39) |
|
probably null |
Het |
| Gtf3c1 |
A |
T |
7: 125,262,188 (GRCm39) |
Y1119* |
probably null |
Het |
| Hgd |
A |
T |
16: 37,409,047 (GRCm39) |
|
probably benign |
Het |
| Ildr2 |
G |
T |
1: 166,136,468 (GRCm39) |
V436L |
probably benign |
Het |
| Intu |
G |
A |
3: 40,629,735 (GRCm39) |
C355Y |
probably damaging |
Het |
| Irf2bpl |
G |
T |
12: 86,929,870 (GRCm39) |
P268T |
probably benign |
Het |
| Jarid2 |
T |
C |
13: 44,994,358 (GRCm39) |
|
probably null |
Het |
| Jup |
A |
T |
11: 100,263,227 (GRCm39) |
M716K |
probably benign |
Het |
| Kank1 |
G |
A |
19: 25,388,837 (GRCm39) |
V809I |
probably damaging |
Het |
| Kdm1b |
T |
A |
13: 47,217,720 (GRCm39) |
|
probably benign |
Het |
| Kdm3a |
C |
T |
6: 71,577,739 (GRCm39) |
C687Y |
probably damaging |
Het |
| Kdm5d |
T |
A |
Y: 942,437 (GRCm39) |
|
probably benign |
Het |
| Kifap3 |
T |
A |
1: 163,693,121 (GRCm39) |
|
probably benign |
Het |
| Macf1 |
T |
A |
4: 123,377,453 (GRCm39) |
K1400* |
probably null |
Het |
| Majin |
A |
G |
19: 6,262,147 (GRCm39) |
|
probably benign |
Het |
| Mctp1 |
A |
G |
13: 77,168,940 (GRCm39) |
I846V |
probably benign |
Het |
| Mrgpra2b |
T |
A |
7: 47,113,875 (GRCm39) |
I286F |
possibly damaging |
Het |
| Neil3 |
T |
G |
8: 54,062,431 (GRCm39) |
|
probably benign |
Het |
| Nox3 |
G |
T |
17: 3,745,838 (GRCm39) |
N23K |
probably damaging |
Het |
| Nt5c3 |
T |
C |
6: 56,860,797 (GRCm39) |
K219E |
probably benign |
Het |
| Or1e29 |
T |
A |
11: 73,667,263 (GRCm39) |
M297L |
probably benign |
Het |
| Or52b4i |
T |
A |
7: 102,191,893 (GRCm39) |
I250N |
probably damaging |
Het |
| Or5b105 |
G |
A |
19: 13,080,642 (GRCm39) |
R3C |
possibly damaging |
Het |
| Or6b13 |
A |
C |
7: 139,782,029 (GRCm39) |
F218C |
possibly damaging |
Het |
| Or6d13 |
A |
T |
6: 116,517,446 (GRCm39) |
N11Y |
probably damaging |
Het |
| Or8g34 |
T |
C |
9: 39,372,889 (GRCm39) |
L54P |
probably damaging |
Het |
| Pacsin2 |
A |
G |
15: 83,263,996 (GRCm39) |
V347A |
possibly damaging |
Het |
| Pcdhb7 |
A |
T |
18: 37,475,857 (GRCm39) |
E331V |
probably damaging |
Het |
| Pcid2 |
A |
C |
8: 13,131,262 (GRCm39) |
|
probably null |
Het |
| Pcsk9 |
T |
C |
4: 106,307,274 (GRCm39) |
D323G |
possibly damaging |
Het |
| Pdhb |
T |
C |
14: 8,169,801 (GRCm38) |
E203G |
probably damaging |
Het |
| Phlpp2 |
A |
G |
8: 110,655,095 (GRCm39) |
Y630C |
probably benign |
Het |
| Pidd1 |
C |
T |
7: 141,019,046 (GRCm39) |
A812T |
probably damaging |
Het |
| Plau |
G |
A |
14: 20,892,382 (GRCm39) |
R389H |
probably benign |
Het |
| Plekhg6 |
G |
A |
6: 125,341,592 (GRCm39) |
|
probably null |
Het |
| Ppox |
T |
C |
1: 171,105,322 (GRCm39) |
Y321C |
probably damaging |
Het |
| Pxdn |
A |
G |
12: 30,037,065 (GRCm39) |
N281S |
possibly damaging |
Het |
| Pycr3 |
A |
T |
15: 75,790,237 (GRCm39) |
M138K |
probably benign |
Het |
| Radil |
T |
C |
5: 142,483,628 (GRCm39) |
Y526C |
probably damaging |
Het |
| Ranbp3 |
C |
A |
17: 57,014,169 (GRCm39) |
D233E |
probably benign |
Het |
| Rhpn1 |
A |
G |
15: 75,583,721 (GRCm39) |
Q402R |
possibly damaging |
Het |
| Sec23b |
T |
A |
2: 144,410,532 (GRCm39) |
|
probably benign |
Het |
| Sel1l2 |
A |
T |
2: 140,082,832 (GRCm39) |
L602* |
probably null |
Het |
| Sema5b |
G |
A |
16: 35,466,725 (GRCm39) |
G209D |
probably damaging |
Het |
| Svep1 |
T |
C |
4: 58,073,333 (GRCm39) |
Y1992C |
possibly damaging |
Het |
| Syncrip |
T |
A |
9: 88,338,312 (GRCm39) |
|
probably benign |
Het |
| Taar2 |
G |
A |
10: 23,817,393 (GRCm39) |
R311H |
probably benign |
Het |
| Tecrl |
T |
C |
5: 83,502,610 (GRCm39) |
|
probably benign |
Het |
| Tenm4 |
G |
T |
7: 96,427,058 (GRCm39) |
G698C |
probably damaging |
Het |
| Tmem209 |
G |
A |
6: 30,491,181 (GRCm39) |
L259F |
probably damaging |
Het |
| Tmem247 |
G |
A |
17: 87,225,931 (GRCm39) |
E124K |
possibly damaging |
Het |
| Tnks2 |
C |
A |
19: 36,830,221 (GRCm39) |
A218E |
probably damaging |
Het |
| Tppp |
T |
A |
13: 74,169,430 (GRCm39) |
F57I |
probably damaging |
Het |
| Trim36 |
A |
G |
18: 46,305,592 (GRCm39) |
W452R |
probably damaging |
Het |
| Vars2 |
A |
T |
17: 35,975,476 (GRCm39) |
V262E |
probably damaging |
Het |
| Vmn2r92 |
C |
T |
17: 18,388,219 (GRCm39) |
A408V |
probably damaging |
Het |
| Zfp516 |
G |
T |
18: 82,973,897 (GRCm39) |
A32S |
probably benign |
Het |
| Zfy2 |
G |
T |
Y: 2,107,348 (GRCm39) |
L429I |
possibly damaging |
Het |
|
| Other mutations in Synj1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01143:Synj1
|
APN |
16 |
90,748,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01468:Synj1
|
APN |
16 |
90,807,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL02209:Synj1
|
APN |
16 |
90,784,307 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02452:Synj1
|
APN |
16 |
90,758,253 (GRCm39) |
splice site |
probably benign |
|
|
IGL02619:Synj1
|
APN |
16 |
90,770,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02650:Synj1
|
APN |
16 |
90,773,584 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02708:Synj1
|
APN |
16 |
90,788,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02863:Synj1
|
APN |
16 |
90,758,322 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03131:Synj1
|
APN |
16 |
90,785,056 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03295:Synj1
|
APN |
16 |
90,735,318 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL03356:Synj1
|
APN |
16 |
90,784,280 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Synj1
|
UTSW |
16 |
90,761,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0179:Synj1
|
UTSW |
16 |
90,761,519 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0396:Synj1
|
UTSW |
16 |
90,735,528 (GRCm39) |
missense |
probably benign |
|
|
R0486:Synj1
|
UTSW |
16 |
90,735,151 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R0515:Synj1
|
UTSW |
16 |
90,790,910 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0535:Synj1
|
UTSW |
16 |
90,744,975 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0697:Synj1
|
UTSW |
16 |
90,757,503 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0698:Synj1
|
UTSW |
16 |
90,757,503 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0945:Synj1
|
UTSW |
16 |
90,757,333 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1327:Synj1
|
UTSW |
16 |
90,743,743 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1562:Synj1
|
UTSW |
16 |
90,784,290 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1732:Synj1
|
UTSW |
16 |
90,761,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1752:Synj1
|
UTSW |
16 |
90,735,361 (GRCm39) |
missense |
probably benign |
|
|
R1785:Synj1
|
UTSW |
16 |
90,761,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1786:Synj1
|
UTSW |
16 |
90,761,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2011:Synj1
|
UTSW |
16 |
90,735,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2012:Synj1
|
UTSW |
16 |
90,735,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2065:Synj1
|
UTSW |
16 |
90,788,537 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2862:Synj1
|
UTSW |
16 |
90,766,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3026:Synj1
|
UTSW |
16 |
90,775,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3151:Synj1
|
UTSW |
16 |
90,757,514 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3946:Synj1
|
UTSW |
16 |
90,806,984 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R3971:Synj1
|
UTSW |
16 |
90,788,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4472:Synj1
|
UTSW |
16 |
90,766,069 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4547:Synj1
|
UTSW |
16 |
90,785,170 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4647:Synj1
|
UTSW |
16 |
90,770,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4739:Synj1
|
UTSW |
16 |
90,752,307 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Synj1
|
UTSW |
16 |
90,737,407 (GRCm39) |
splice site |
probably null |
|
|
R5428:Synj1
|
UTSW |
16 |
90,788,406 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5586:Synj1
|
UTSW |
16 |
90,806,865 (GRCm39) |
intron |
probably benign |
|
|
R5769:Synj1
|
UTSW |
16 |
90,735,141 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R6005:Synj1
|
UTSW |
16 |
90,766,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6119:Synj1
|
UTSW |
16 |
90,735,877 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6313:Synj1
|
UTSW |
16 |
90,743,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6324:Synj1
|
UTSW |
16 |
90,735,518 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6549:Synj1
|
UTSW |
16 |
90,735,565 (GRCm39) |
missense |
probably benign |
|
|
R6696:Synj1
|
UTSW |
16 |
90,757,340 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6698:Synj1
|
UTSW |
16 |
90,757,340 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6861:Synj1
|
UTSW |
16 |
90,760,768 (GRCm39) |
nonsense |
probably null |
|
|
R7008:Synj1
|
UTSW |
16 |
90,790,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7153:Synj1
|
UTSW |
16 |
90,744,978 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7393:Synj1
|
UTSW |
16 |
90,748,887 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7510:Synj1
|
UTSW |
16 |
90,735,565 (GRCm39) |
missense |
probably benign |
|
|
R7560:Synj1
|
UTSW |
16 |
90,737,371 (GRCm39) |
missense |
probably benign |
|
|
R7724:Synj1
|
UTSW |
16 |
90,758,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7913:Synj1
|
UTSW |
16 |
90,788,315 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8326:Synj1
|
UTSW |
16 |
90,785,084 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8707:Synj1
|
UTSW |
16 |
90,752,319 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8711:Synj1
|
UTSW |
16 |
90,806,971 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8767:Synj1
|
UTSW |
16 |
90,758,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8911:Synj1
|
UTSW |
16 |
90,775,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Synj1
|
UTSW |
16 |
90,735,728 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9124:Synj1
|
UTSW |
16 |
90,735,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9307:Synj1
|
UTSW |
16 |
90,785,095 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9408:Synj1
|
UTSW |
16 |
90,741,740 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9458:Synj1
|
UTSW |
16 |
90,766,200 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9567:Synj1
|
UTSW |
16 |
90,790,912 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9651:Synj1
|
UTSW |
16 |
90,757,343 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9651:Synj1
|
UTSW |
16 |
90,735,412 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Synj1
|
UTSW |
16 |
90,758,300 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9730:Synj1
|
UTSW |
16 |
90,757,552 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9732:Synj1
|
UTSW |
16 |
90,761,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Synj1
|
UTSW |
16 |
90,784,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAAAAGCCATCTTGCCAGTTCCG -3'
(R):5'- AAAGCTTAGAGCCTTCCAGCTTCAG -3'
Sequencing Primer
(F):5'- AGACTCATACCAAAAATACTGAGAAC -3'
(R):5'- ACTCAGTTCCCCCAGTAAGG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation