Mutagenetix > Incidental Mutation

Incidental Mutation 'R5089:Bltp1'

387626

Institutional Source

Beutler Lab

Gene Symbol

Bltp1

Ensembl Gene

ENSMUSG00000037270

Gene Name

bridge-like lipid transfer protein family member 1

Synonyms

FSA, 4932438A13Rik, Tweek

MMRRC Submission

042678-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5089 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

36863104-37053033 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 36987502 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 2676 (D2676E)

Ref Sequence

ENSEMBL: ENSMUSP00000148720 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000152564] [ENSMUST00000211820]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000057272
AA Change: D2675E

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000060199
Gene: ENSMUSG00000037270
AA Change: D2675E

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000152564
AA Change: D2675E

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000117808
Gene: ENSMUSG00000037270
AA Change: D2675E

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000211820
AA Change: D2676E

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

Meta Mutation Damage Score

0.0735

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.0%
20x: 91.3%

Validation Efficiency

98% (65/66)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700030J22Rik	T	C	8: 116,971,933 (GRCm38)	N145S	possibly damaging	Het
Acp2	T	C	2: 91,211,922 (GRCm38)		probably benign	Het
Adgrf2	G	A	17: 42,710,097 (GRCm38)	A612V	probably benign	Het
Cct3	T	G	3: 88,300,843 (GRCm38)	M46R	probably damaging	Het
Cdc123	T	C	2: 5,805,000 (GRCm38)	D200G	probably benign	Het
Cdh9	T	A	15: 16,778,276 (GRCm38)	F59Y	probably damaging	Het
Cluh	A	G	11: 74,660,372 (GRCm38)	E349G	probably damaging	Het
Col16a1	C	T	4: 130,079,195 (GRCm38)	T643M	probably benign	Het
Col5a1	G	A	2: 28,018,602 (GRCm38)	W67*	probably null	Het
Crbn	T	C	6: 106,781,718 (GRCm38)	H381R	possibly damaging	Het
Crim1	A	G	17: 78,374,090 (GRCm38)	D991G	probably damaging	Het
Dhx16	A	T	17: 35,884,089 (GRCm38)	M503L	probably damaging	Het
Dthd1	A	G	5: 62,849,905 (GRCm38)	T650A	probably benign	Het
Etfa	T	A	9: 55,488,866 (GRCm38)	K139*	probably null	Het
Flnc	T	C	6: 29,447,813 (GRCm38)	I1205T	probably damaging	Het
Fzd6	T	A	15: 39,007,480 (GRCm38)	C32S	probably damaging	Het
Gm1110	T	A	9: 26,882,387 (GRCm38)	D515V	probably damaging	Het
Gm7676	T	C	8: 13,896,401 (GRCm38)		noncoding transcript	Het
Gpr157	T	C	4: 150,102,293 (GRCm38)	S293P	possibly damaging	Het
Hc	T	C	2: 35,024,890 (GRCm38)	D810G	probably benign	Het
Helz2	T	C	2: 181,235,149 (GRCm38)	H1184R	probably benign	Het
Hoxc5	A	T	15: 103,014,055 (GRCm38)		probably benign	Het
Iah1	C	T	12: 21,323,308 (GRCm38)	S196L	possibly damaging	Het
Il5	C	T	11: 53,721,828 (GRCm38)	T55I	possibly damaging	Het
Kras	T	C	6: 145,225,143 (GRCm38)	K169E	probably benign	Het
Larp1	C	A	11: 58,047,867 (GRCm38)	T492K	possibly damaging	Het
Lgr5	T	C	10: 115,478,423 (GRCm38)	D203G	probably damaging	Het
Lpcat2	G	A	8: 92,879,443 (GRCm38)	V241M	probably damaging	Het
Mpeg1	G	A	19: 12,462,997 (GRCm38)	M606I	probably benign	Het
Ms4a1	G	A	19: 11,258,812 (GRCm38)	P4S	probably benign	Het
Nat10	A	T	2: 103,757,143 (GRCm38)		probably benign	Het
Ncaph2	T	A	15: 89,355,945 (GRCm38)		probably null	Het
Nfat5	T	A	8: 107,351,438 (GRCm38)	V403D	probably damaging	Het
Or2y10	T	A	11: 49,564,413 (GRCm38)	M164K	possibly damaging	Het
Or4c109	A	G	2: 88,988,172 (GRCm38)	F10S	probably damaging	Het
Pax7	T	C	4: 139,830,265 (GRCm38)	H65R	probably damaging	Het
Phf20	C	A	2: 156,302,862 (GRCm38)	H797N	probably benign	Het
Pkhd1l1	T	A	15: 44,591,887 (GRCm38)	S4015T	probably benign	Het
Prdm5	C	T	6: 65,856,090 (GRCm38)	H148Y	probably benign	Het
Prpf8	A	G	11: 75,509,228 (GRCm38)		probably null	Het
Rangap1	A	C	15: 81,710,463 (GRCm38)	D388E	probably benign	Het
Sardh	A	G	2: 27,239,613 (GRCm38)		probably null	Het
Serpinb6b	G	A	13: 32,978,150 (GRCm38)	E192K	probably benign	Het
Shfl	A	T	9: 20,868,916 (GRCm38)	M1L	probably benign	Het
Skor1	A	G	9: 63,145,923 (GRCm38)	S216P	probably damaging	Het
Slc51a	A	G	16: 32,477,546 (GRCm38)		probably null	Het
Smarcb1	T	C	10: 75,915,179 (GRCm38)	T74A	probably benign	Het
Spg11	A	T	2: 122,114,717 (GRCm38)	Y107*	probably null	Het
Spmip5	A	T	19: 58,786,246 (GRCm38)	L176H	probably damaging	Het
Stk25	T	A	1: 93,624,608 (GRCm38)	K350M	probably benign	Het
Syne1	C	T	10: 5,405,444 (GRCm38)	W379*	probably null	Het
Taco1	A	T	11: 106,069,611 (GRCm38)	E126V	probably benign	Het
Tbc1d12	T	A	19: 38,916,788 (GRCm38)	L649*	probably null	Het
Trpm3	G	A	19: 22,766,756 (GRCm38)	G238R	probably damaging	Het
Yy1	C	A	12: 108,793,737 (GRCm38)	Q109K	probably damaging	Het

Other mutations in Bltp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00428:Bltp1	APN	3	37,011,727 (GRCm38)	missense	probably benign	0.00
IGL00434:Bltp1	APN	3	36,987,299 (GRCm38)	missense	probably damaging	0.98
IGL00640:Bltp1	APN	3	36,908,218 (GRCm38)	missense	probably damaging	1.00
IGL00693:Bltp1	APN	3	37,052,547 (GRCm38)	utr 3 prime	probably benign
IGL00721:Bltp1	APN	3	37,030,751 (GRCm38)	splice site	probably null
IGL00756:Bltp1	APN	3	36,908,218 (GRCm38)	missense	probably damaging	1.00
IGL00896:Bltp1	APN	3	37,039,462 (GRCm38)	missense	probably benign
IGL00902:Bltp1	APN	3	37,041,345 (GRCm38)	missense	probably damaging	1.00
IGL00980:Bltp1	APN	3	37,000,041 (GRCm38)	missense	probably damaging	1.00
IGL01019:Bltp1	APN	3	37,006,984 (GRCm38)	critical splice acceptor site	probably null
IGL01025:Bltp1	APN	3	37,046,280 (GRCm38)	missense	possibly damaging	0.89
IGL01306:Bltp1	APN	3	37,005,013 (GRCm38)	splice site	probably benign
IGL01370:Bltp1	APN	3	36,947,755 (GRCm38)	missense	probably benign	0.07
IGL01377:Bltp1	APN	3	36,973,452 (GRCm38)	critical splice donor site	probably null
IGL01401:Bltp1	APN	3	36,942,292 (GRCm38)	missense	probably benign
IGL01419:Bltp1	APN	3	37,048,121 (GRCm38)	missense	probably damaging	1.00
IGL01432:Bltp1	APN	3	37,003,759 (GRCm38)	missense	possibly damaging	0.87
IGL01433:Bltp1	APN	3	36,887,770 (GRCm38)	missense	probably damaging	1.00
IGL01452:Bltp1	APN	3	36,996,308 (GRCm38)	unclassified	probably benign
IGL01520:Bltp1	APN	3	36,973,260 (GRCm38)	nonsense	probably null
IGL01524:Bltp1	APN	3	36,942,382 (GRCm38)	missense	possibly damaging	0.90
IGL01628:Bltp1	APN	3	37,008,485 (GRCm38)	missense	probably damaging	1.00
IGL01638:Bltp1	APN	3	36,974,311 (GRCm38)	missense	probably damaging	1.00
IGL01650:Bltp1	APN	3	36,992,673 (GRCm38)	splice site	probably benign
IGL01717:Bltp1	APN	3	37,034,736 (GRCm38)	missense	probably benign
IGL01767:Bltp1	APN	3	37,041,363 (GRCm38)	missense	probably benign	0.29
IGL01813:Bltp1	APN	3	36,928,520 (GRCm38)	missense	possibly damaging	0.90
IGL01998:Bltp1	APN	3	36,957,016 (GRCm38)	missense	possibly damaging	0.49
IGL02172:Bltp1	APN	3	37,004,873 (GRCm38)	missense	probably damaging	0.99
IGL02197:Bltp1	APN	3	36,906,735 (GRCm38)	missense	probably damaging	1.00
IGL02248:Bltp1	APN	3	36,969,290 (GRCm38)	critical splice donor site	probably null
IGL02273:Bltp1	APN	3	36,921,437 (GRCm38)	splice site	probably benign
IGL02403:Bltp1	APN	3	37,030,664 (GRCm38)	missense	probably benign
IGL02492:Bltp1	APN	3	37,048,113 (GRCm38)	missense	probably benign	0.04
IGL02517:Bltp1	APN	3	36,958,868 (GRCm38)	missense	probably damaging	1.00
IGL02519:Bltp1	APN	3	36,895,315 (GRCm38)	missense	probably damaging	1.00
IGL02586:Bltp1	APN	3	37,044,608 (GRCm38)	nonsense	probably null
IGL02620:Bltp1	APN	3	37,035,945 (GRCm38)	missense	possibly damaging	0.95
IGL02621:Bltp1	APN	3	37,041,484 (GRCm38)	splice site	probably benign
IGL02670:Bltp1	APN	3	36,967,305 (GRCm38)	nonsense	probably null
IGL02806:Bltp1	APN	3	36,946,494 (GRCm38)	missense	possibly damaging	0.95
IGL02985:Bltp1	APN	3	36,958,757 (GRCm38)	missense	probably damaging	0.99
IGL03004:Bltp1	APN	3	36,965,677 (GRCm38)	splice site	probably benign
IGL03037:Bltp1	APN	3	36,969,207 (GRCm38)	missense	probably benign	0.23
IGL03037:Bltp1	APN	3	36,969,208 (GRCm38)	missense	probably damaging	1.00
IGL03062:Bltp1	APN	3	37,038,517 (GRCm38)	splice site	probably benign
IGL03137:Bltp1	APN	3	37,034,602 (GRCm38)	missense	probably damaging	0.98
IGL03150:Bltp1	APN	3	36,948,066 (GRCm38)	missense	probably damaging	1.00
IGL03204:Bltp1	APN	3	37,050,934 (GRCm38)	splice site	probably benign
IGL03207:Bltp1	APN	3	36,949,996 (GRCm38)	missense	possibly damaging	0.73
IGL03256:Bltp1	APN	3	36,906,683 (GRCm38)	splice site	probably benign
IGL03264:Bltp1	APN	3	37,002,635 (GRCm38)	missense	probably damaging	1.00
IGL03265:Bltp1	APN	3	37,047,991 (GRCm38)	missense	probably benign	0.00
IGL03303:Bltp1	APN	3	36,870,077 (GRCm38)	missense	possibly damaging	0.90
admonished	UTSW	3	36,948,304 (GRCm38)	missense	probably damaging	1.00
alerted	UTSW	3	37,033,265 (GRCm38)	missense	possibly damaging	0.85
informed	UTSW	3	36,965,849 (GRCm38)	missense	probably damaging	1.00
resolved	UTSW	3	36,921,221 (GRCm38)	missense	possibly damaging	0.60
tipped	UTSW	3	36,988,085 (GRCm38)	missense	possibly damaging	0.81
warned	UTSW	3	36,965,621 (GRCm38)	missense	probably damaging	1.00
FR4340:Bltp1	UTSW	3	37,050,752 (GRCm38)	critical splice acceptor site	probably benign
FR4737:Bltp1	UTSW	3	37,050,754 (GRCm38)	critical splice acceptor site	probably benign
PIT4515001:Bltp1	UTSW	3	36,974,236 (GRCm38)	missense	probably damaging	1.00
R0035:Bltp1	UTSW	3	36,987,598 (GRCm38)	nonsense	probably null
R0047:Bltp1	UTSW	3	36,908,192 (GRCm38)	missense	possibly damaging	0.83
R0047:Bltp1	UTSW	3	36,908,192 (GRCm38)	missense	possibly damaging	0.83
R0068:Bltp1	UTSW	3	36,952,221 (GRCm38)	missense	probably benign	0.28
R0068:Bltp1	UTSW	3	36,952,221 (GRCm38)	missense	probably benign	0.28
R0092:Bltp1	UTSW	3	37,028,159 (GRCm38)	missense	probably benign	0.41
R0233:Bltp1	UTSW	3	36,948,563 (GRCm38)	nonsense	probably null
R0233:Bltp1	UTSW	3	36,948,563 (GRCm38)	nonsense	probably null
R0256:Bltp1	UTSW	3	36,917,773 (GRCm38)	missense	probably benign	0.01
R0277:Bltp1	UTSW	3	36,943,182 (GRCm38)	nonsense	probably null
R0321:Bltp1	UTSW	3	36,906,788 (GRCm38)	splice site	probably null
R0323:Bltp1	UTSW	3	36,943,182 (GRCm38)	nonsense	probably null
R0335:Bltp1	UTSW	3	36,969,152 (GRCm38)	missense	probably damaging	1.00
R0375:Bltp1	UTSW	3	37,046,252 (GRCm38)	missense	probably damaging	0.99
R0437:Bltp1	UTSW	3	36,989,804 (GRCm38)	missense	possibly damaging	0.81
R0445:Bltp1	UTSW	3	37,000,065 (GRCm38)	missense	probably damaging	0.99
R0496:Bltp1	UTSW	3	36,987,635 (GRCm38)	missense	probably damaging	1.00
R0531:Bltp1	UTSW	3	37,036,825 (GRCm38)	missense	probably damaging	1.00
R0543:Bltp1	UTSW	3	36,996,458 (GRCm38)	missense	probably benign	0.22
R0545:Bltp1	UTSW	3	36,987,690 (GRCm38)	splice site	probably benign
R0674:Bltp1	UTSW	3	37,044,626 (GRCm38)	missense	possibly damaging	0.86
R0745:Bltp1	UTSW	3	36,928,463 (GRCm38)	missense	probably damaging	1.00
R0755:Bltp1	UTSW	3	36,946,364 (GRCm38)	missense	probably damaging	1.00
R0785:Bltp1	UTSW	3	36,959,334 (GRCm38)	splice site	probably benign
R1056:Bltp1	UTSW	3	37,044,680 (GRCm38)	missense	probably benign	0.44
R1056:Bltp1	UTSW	3	36,983,453 (GRCm38)	missense	possibly damaging	0.69
R1080:Bltp1	UTSW	3	36,988,255 (GRCm38)	missense	probably damaging	1.00
R1103:Bltp1	UTSW	3	36,996,523 (GRCm38)	missense	probably benign
R1119:Bltp1	UTSW	3	36,987,045 (GRCm38)	missense	probably damaging	1.00
R1170:Bltp1	UTSW	3	37,044,631 (GRCm38)	missense	probably damaging	0.98
R1183:Bltp1	UTSW	3	36,895,303 (GRCm38)	missense	possibly damaging	0.51
R1186:Bltp1	UTSW	3	36,996,312 (GRCm38)	unclassified	probably benign
R1201:Bltp1	UTSW	3	36,948,375 (GRCm38)	missense	probably benign
R1219:Bltp1	UTSW	3	36,946,470 (GRCm38)	nonsense	probably null
R1270:Bltp1	UTSW	3	36,952,184 (GRCm38)	missense	probably damaging	1.00
R1273:Bltp1	UTSW	3	36,987,210 (GRCm38)	missense	probably damaging	1.00
R1338:Bltp1	UTSW	3	37,052,535 (GRCm38)	missense	unknown
R1364:Bltp1	UTSW	3	36,987,030 (GRCm38)	missense	probably damaging	1.00
R1437:Bltp1	UTSW	3	36,942,429 (GRCm38)	missense	possibly damaging	0.65
R1447:Bltp1	UTSW	3	36,965,586 (GRCm38)	missense	probably damaging	0.98
R1467:Bltp1	UTSW	3	37,035,945 (GRCm38)	missense	probably damaging	0.99
R1467:Bltp1	UTSW	3	37,035,945 (GRCm38)	missense	probably damaging	0.99
R1470:Bltp1	UTSW	3	36,998,331 (GRCm38)	missense	probably benign	0.31
R1470:Bltp1	UTSW	3	36,998,331 (GRCm38)	missense	probably benign	0.31
R1481:Bltp1	UTSW	3	37,008,434 (GRCm38)	missense	probably damaging	0.99
R1528:Bltp1	UTSW	3	37,052,535 (GRCm38)	missense	unknown
R1533:Bltp1	UTSW	3	37,041,375 (GRCm38)	missense	probably damaging	1.00
R1546:Bltp1	UTSW	3	36,870,056 (GRCm38)	missense	possibly damaging	0.64
R1606:Bltp1	UTSW	3	36,942,399 (GRCm38)	missense	probably damaging	1.00
R1638:Bltp1	UTSW	3	37,035,812 (GRCm38)	nonsense	probably null
R1772:Bltp1	UTSW	3	36,959,432 (GRCm38)	missense	probably damaging	1.00
R1896:Bltp1	UTSW	3	36,908,231 (GRCm38)	nonsense	probably null
R1919:Bltp1	UTSW	3	37,006,983 (GRCm38)	critical splice acceptor site	probably null
R1983:Bltp1	UTSW	3	36,887,865 (GRCm38)	missense	probably null	1.00
R1987:Bltp1	UTSW	3	36,953,985 (GRCm38)	critical splice donor site	probably null
R1992:Bltp1	UTSW	3	37,000,032 (GRCm38)	missense	probably benign	0.32
R1999:Bltp1	UTSW	3	36,908,211 (GRCm38)	missense	probably damaging	1.00
R2004:Bltp1	UTSW	3	36,895,378 (GRCm38)	missense	possibly damaging	0.77
R2010:Bltp1	UTSW	3	36,928,551 (GRCm38)	missense	probably benign	0.09
R2027:Bltp1	UTSW	3	37,047,961 (GRCm38)	splice site	probably benign
R2039:Bltp1	UTSW	3	37,003,878 (GRCm38)	missense	possibly damaging	0.66
R2054:Bltp1	UTSW	3	36,947,853 (GRCm38)	missense	probably benign	0.01
R2089:Bltp1	UTSW	3	36,988,256 (GRCm38)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	36,988,256 (GRCm38)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	36,988,256 (GRCm38)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	36,953,970 (GRCm38)	missense	probably damaging	1.00
R2220:Bltp1	UTSW	3	36,875,530 (GRCm38)	critical splice donor site	probably null
R2374:Bltp1	UTSW	3	36,885,396 (GRCm38)	missense	probably benign	0.00
R2437:Bltp1	UTSW	3	36,958,685 (GRCm38)	splice site	probably null
R2860:Bltp1	UTSW	3	36,965,849 (GRCm38)	missense	probably damaging	1.00
R2861:Bltp1	UTSW	3	36,965,849 (GRCm38)	missense	probably damaging	1.00
R2909:Bltp1	UTSW	3	36,947,953 (GRCm38)	missense	probably damaging	1.00
R2925:Bltp1	UTSW	3	37,007,122 (GRCm38)	missense	probably damaging	0.99
R2940:Bltp1	UTSW	3	36,958,805 (GRCm38)	missense	probably damaging	1.00
R3015:Bltp1	UTSW	3	36,875,462 (GRCm38)	missense	probably damaging	1.00
R3086:Bltp1	UTSW	3	37,011,703 (GRCm38)	missense	possibly damaging	0.56
R3159:Bltp1	UTSW	3	36,959,415 (GRCm38)	missense	probably benign	0.17
R3440:Bltp1	UTSW	3	37,041,912 (GRCm38)	nonsense	probably null
R3703:Bltp1	UTSW	3	36,987,581 (GRCm38)	missense	probably damaging	1.00
R3705:Bltp1	UTSW	3	36,987,581 (GRCm38)	missense	probably damaging	1.00
R3795:Bltp1	UTSW	3	37,030,565 (GRCm38)	missense	probably benign	0.30
R3820:Bltp1	UTSW	3	37,040,434 (GRCm38)	missense	probably damaging	1.00
R3862:Bltp1	UTSW	3	36,885,398 (GRCm38)	missense	possibly damaging	0.73
R3944:Bltp1	UTSW	3	37,030,061 (GRCm38)	missense	possibly damaging	0.90
R4020:Bltp1	UTSW	3	37,012,575 (GRCm38)	intron	probably benign
R4091:Bltp1	UTSW	3	37,030,589 (GRCm38)	missense	probably benign	0.00
R4159:Bltp1	UTSW	3	36,931,083 (GRCm38)	missense	probably benign	0.00
R4231:Bltp1	UTSW	3	36,920,236 (GRCm38)	missense	probably benign	0.10
R4368:Bltp1	UTSW	3	36,988,147 (GRCm38)	nonsense	probably null
R4413:Bltp1	UTSW	3	36,958,681 (GRCm38)	splice site	probably null
R4475:Bltp1	UTSW	3	37,040,395 (GRCm38)	missense	probably damaging	1.00
R4488:Bltp1	UTSW	3	37,003,933 (GRCm38)	missense	probably null	0.93
R4489:Bltp1	UTSW	3	37,003,933 (GRCm38)	missense	probably null	0.93
R4516:Bltp1	UTSW	3	36,895,311 (GRCm38)	missense	possibly damaging	0.90
R4580:Bltp1	UTSW	3	37,030,025 (GRCm38)	missense	probably benign	0.02
R4672:Bltp1	UTSW	3	36,889,990 (GRCm38)	makesense	probably null
R4705:Bltp1	UTSW	3	37,041,889 (GRCm38)	missense	probably benign	0.03
R4735:Bltp1	UTSW	3	37,004,967 (GRCm38)	missense	possibly damaging	0.84
R4741:Bltp1	UTSW	3	36,942,375 (GRCm38)	missense	probably damaging	0.99
R4754:Bltp1	UTSW	3	37,022,466 (GRCm38)	nonsense	probably null
R4778:Bltp1	UTSW	3	36,937,065 (GRCm38)	missense	possibly damaging	0.90
R4833:Bltp1	UTSW	3	36,964,968 (GRCm38)	missense	probably damaging	0.96
R4896:Bltp1	UTSW	3	36,965,937 (GRCm38)	missense	probably damaging	1.00
R4910:Bltp1	UTSW	3	36,998,199 (GRCm38)	missense	probably damaging	1.00
R4922:Bltp1	UTSW	3	36,987,165 (GRCm38)	missense	probably damaging	1.00
R4941:Bltp1	UTSW	3	36,919,901 (GRCm38)	missense	probably benign	0.41
R4941:Bltp1	UTSW	3	36,917,702 (GRCm38)	missense	probably damaging	1.00
R4980:Bltp1	UTSW	3	36,943,312 (GRCm38)	missense	probably damaging	1.00
R5030:Bltp1	UTSW	3	36,943,399 (GRCm38)	intron	probably benign
R5049:Bltp1	UTSW	3	37,041,390 (GRCm38)	missense	probably damaging	1.00
R5049:Bltp1	UTSW	3	37,040,506 (GRCm38)	intron	probably benign
R5092:Bltp1	UTSW	3	37,000,085 (GRCm38)	missense	probably benign	0.14
R5122:Bltp1	UTSW	3	37,034,757 (GRCm38)	splice site	probably null
R5210:Bltp1	UTSW	3	37,033,265 (GRCm38)	missense	possibly damaging	0.85
R5246:Bltp1	UTSW	3	37,048,050 (GRCm38)	missense	probably damaging	1.00
R5289:Bltp1	UTSW	3	37,000,109 (GRCm38)	missense	probably damaging	0.97
R5348:Bltp1	UTSW	3	37,048,146 (GRCm38)	missense	probably damaging	1.00
R5394:Bltp1	UTSW	3	36,917,668 (GRCm38)	missense	probably damaging	1.00
R5434:Bltp1	UTSW	3	36,875,516 (GRCm38)	missense	probably damaging	1.00
R5667:Bltp1	UTSW	3	36,917,677 (GRCm38)	missense	probably benign	0.00
R5686:Bltp1	UTSW	3	36,917,660 (GRCm38)	missense	probably benign	0.00
R5701:Bltp1	UTSW	3	36,921,360 (GRCm38)	missense	probably benign	0.10
R5778:Bltp1	UTSW	3	36,958,714 (GRCm38)	missense	probably damaging	1.00
R5787:Bltp1	UTSW	3	36,992,733 (GRCm38)	splice site	probably null
R5800:Bltp1	UTSW	3	37,052,443 (GRCm38)	missense	probably damaging	1.00
R5819:Bltp1	UTSW	3	37,048,600 (GRCm38)	missense	probably benign	0.12
R5820:Bltp1	UTSW	3	37,039,526 (GRCm38)	missense	probably benign	0.00
R5952:Bltp1	UTSW	3	36,965,621 (GRCm38)	missense	probably damaging	1.00
R5975:Bltp1	UTSW	3	36,969,221 (GRCm38)	missense	possibly damaging	0.64
R5996:Bltp1	UTSW	3	36,931,116 (GRCm38)	missense	probably benign	0.07
R6192:Bltp1	UTSW	3	36,988,169 (GRCm38)	missense	probably benign	0.00
R6225:Bltp1	UTSW	3	36,948,304 (GRCm38)	missense	probably damaging	1.00
R6234:Bltp1	UTSW	3	36,983,471 (GRCm38)	missense	probably benign	0.00
R6244:Bltp1	UTSW	3	36,956,999 (GRCm38)	missense	probably benign
R6263:Bltp1	UTSW	3	36,931,111 (GRCm38)	missense	probably benign	0.06
R6351:Bltp1	UTSW	3	36,908,228 (GRCm38)	missense	probably damaging	1.00
R6380:Bltp1	UTSW	3	37,033,307 (GRCm38)	missense	probably benign	0.19
R6468:Bltp1	UTSW	3	37,008,443 (GRCm38)	missense	probably damaging	1.00
R6759:Bltp1	UTSW	3	36,988,085 (GRCm38)	missense	possibly damaging	0.81
R6792:Bltp1	UTSW	3	37,011,566 (GRCm38)	critical splice acceptor site	probably null
R6809:Bltp1	UTSW	3	36,874,282 (GRCm38)	missense	probably damaging	0.98
R6841:Bltp1	UTSW	3	37,021,481 (GRCm38)	missense	probably damaging	1.00
R6959:Bltp1	UTSW	3	36,967,189 (GRCm38)	missense	probably damaging	1.00
R7102:Bltp1	UTSW	3	36,940,798 (GRCm38)	missense	probably damaging	0.99
R7188:Bltp1	UTSW	3	36,950,013 (GRCm38)	missense	probably benign	0.06
R7212:Bltp1	UTSW	3	37,048,009 (GRCm38)	missense
R7425:Bltp1	UTSW	3	36,983,394 (GRCm38)	missense	probably benign	0.02
R7425:Bltp1	UTSW	3	36,948,341 (GRCm38)	missense	probably benign
R7451:Bltp1	UTSW	3	37,022,807 (GRCm38)	splice site	probably null
R7604:Bltp1	UTSW	3	36,949,843 (GRCm38)	splice site	probably null
R7622:Bltp1	UTSW	3	36,948,413 (GRCm38)	nonsense	probably null
R7671:Bltp1	UTSW	3	36,943,231 (GRCm38)	missense	probably damaging	0.99
R7699:Bltp1	UTSW	3	37,026,154 (GRCm38)	missense	probably benign	0.00
R7699:Bltp1	UTSW	3	36,974,172 (GRCm38)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	36,974,172 (GRCm38)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,026,154 (GRCm38)	missense	probably benign	0.00
R7748:Bltp1	UTSW	3	36,959,335 (GRCm38)	critical splice acceptor site	probably null
R7767:Bltp1	UTSW	3	36,920,287 (GRCm38)	critical splice donor site	probably null
R7787:Bltp1	UTSW	3	36,885,408 (GRCm38)	missense	probably damaging	1.00
R7830:Bltp1	UTSW	3	36,964,932 (GRCm38)	frame shift	probably null
R7849:Bltp1	UTSW	3	37,026,328 (GRCm38)	missense
R7912:Bltp1	UTSW	3	37,007,069 (GRCm38)	missense	probably damaging	0.99
R7914:Bltp1	UTSW	3	36,946,283 (GRCm38)	missense	probably benign	0.13
R7945:Bltp1	UTSW	3	36,965,893 (GRCm38)	missense	probably benign	0.03
R8039:Bltp1	UTSW	3	36,943,214 (GRCm38)	missense	probably benign	0.12
R8101:Bltp1	UTSW	3	37,008,502 (GRCm38)	missense	probably damaging	1.00
R8143:Bltp1	UTSW	3	36,946,508 (GRCm38)	critical splice donor site	probably null
R8145:Bltp1	UTSW	3	36,998,267 (GRCm38)	missense	probably damaging	1.00
R8171:Bltp1	UTSW	3	36,975,713 (GRCm38)	missense	probably benign	0.00
R8210:Bltp1	UTSW	3	37,012,881 (GRCm38)	missense
R8250:Bltp1	UTSW	3	36,917,662 (GRCm38)	missense	probably damaging	0.99
R8369:Bltp1	UTSW	3	37,011,603 (GRCm38)	missense
R8478:Bltp1	UTSW	3	37,033,277 (GRCm38)	missense	possibly damaging	0.74
R8558:Bltp1	UTSW	3	37,048,601 (GRCm38)	missense
R8688:Bltp1	UTSW	3	37,035,917 (GRCm38)	missense
R8724:Bltp1	UTSW	3	36,890,893 (GRCm38)	missense	probably damaging	0.99
R8818:Bltp1	UTSW	3	36,996,548 (GRCm38)	missense	possibly damaging	0.60
R8869:Bltp1	UTSW	3	36,958,858 (GRCm38)	missense	probably damaging	0.99
R8887:Bltp1	UTSW	3	37,033,354 (GRCm38)	missense	possibly damaging	0.95
R8899:Bltp1	UTSW	3	36,988,280 (GRCm38)	missense	probably damaging	1.00
R8907:Bltp1	UTSW	3	36,948,146 (GRCm38)	nonsense	probably null
R8960:Bltp1	UTSW	3	37,012,983 (GRCm38)	missense	probably damaging	1.00
R8990:Bltp1	UTSW	3	36,921,221 (GRCm38)	missense	possibly damaging	0.60
R9021:Bltp1	UTSW	3	36,998,344 (GRCm38)	missense	probably benign	0.00
R9048:Bltp1	UTSW	3	37,011,777 (GRCm38)	missense
R9100:Bltp1	UTSW	3	37,044,758 (GRCm38)	missense
R9166:Bltp1	UTSW	3	36,987,367 (GRCm38)	missense	probably damaging	1.00
R9176:Bltp1	UTSW	3	36,956,703 (GRCm38)	missense	possibly damaging	0.82
R9202:Bltp1	UTSW	3	36,890,821 (GRCm38)	missense	probably benign
R9303:Bltp1	UTSW	3	37,044,820 (GRCm38)	missense
R9305:Bltp1	UTSW	3	37,044,820 (GRCm38)	missense
R9332:Bltp1	UTSW	3	37,050,840 (GRCm38)	missense
R9362:Bltp1	UTSW	3	36,957,013 (GRCm38)	missense	probably benign
R9493:Bltp1	UTSW	3	37,011,736 (GRCm38)	missense
R9534:Bltp1	UTSW	3	36,998,270 (GRCm38)	missense	probably benign	0.01
R9569:Bltp1	UTSW	3	37,012,621 (GRCm38)	missense
R9593:Bltp1	UTSW	3	36,947,941 (GRCm38)	missense	probably damaging	1.00
R9600:Bltp1	UTSW	3	37,041,416 (GRCm38)	nonsense	probably null
R9733:Bltp1	UTSW	3	37,048,583 (GRCm38)	missense
R9751:Bltp1	UTSW	3	37,011,740 (GRCm38)	missense
RF013:Bltp1	UTSW	3	37,050,757 (GRCm38)	critical splice acceptor site	probably benign
RF015:Bltp1	UTSW	3	37,050,748 (GRCm38)	critical splice acceptor site	probably benign
RF021:Bltp1	UTSW	3	37,050,748 (GRCm38)	critical splice acceptor site	probably benign
RF023:Bltp1	UTSW	3	37,050,760 (GRCm38)	critical splice acceptor site	probably benign
RF034:Bltp1	UTSW	3	37,050,760 (GRCm38)	critical splice acceptor site	probably benign
RF035:Bltp1	UTSW	3	37,050,758 (GRCm38)	critical splice acceptor site	probably benign
RF055:Bltp1	UTSW	3	37,050,757 (GRCm38)	critical splice acceptor site	probably benign
X0050:Bltp1	UTSW	3	36,957,128 (GRCm38)	missense	probably damaging	1.00
Z1088:Bltp1	UTSW	3	36,987,567 (GRCm38)	missense	probably damaging	1.00
Z1177:Bltp1	UTSW	3	36,983,440 (GRCm38)	missense	possibly damaging	0.88
Z1177:Bltp1	UTSW	3	36,919,950 (GRCm38)	missense	probably benign
Z1177:Bltp1	UTSW	3	37,036,707 (GRCm38)	missense

Predicted Primers

PCR Primer
(F):5'- CGTTCATCTGACTTCAGCCG -3'
(R):5'- GGTGAACAGTCTTCTTTAGCATTTC -3'

Sequencing Primer
(F):5'- ACTTCAGCCGCAGTTCGAGAG -3'
(R):5'- ACAATGCTTGTTACCTGCTGG -3'

Posted On

2016-06-06