Incidental Mutation 'R5092:Kdm3b'
| ID |
387882 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kdm3b
|
| Ensembl Gene |
ENSMUSG00000038773 |
| Gene Name |
KDM3B lysine (K)-specific demethylase 3B |
| Synonyms |
Jmjd1b, 5830462I21Rik, JHDM2B |
| MMRRC Submission |
042681-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.943)
|
| Stock # |
R5092 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
34910100-34971713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 34946515 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 835
(C835S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153446
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043775]
[ENSMUST00000225195]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043775
AA Change: C1035S
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000037628
Gene: ENSMUSG00000038773
AA Change: C1035S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
36 |
N/A |
INTRINSIC |
|
Blast:JmjC
|
149 |
944 |
N/A |
BLAST |
|
Blast:JmjC
|
946 |
1064 |
5e-40 |
BLAST |
|
Blast:JmjC
|
1069 |
1471 |
N/A |
BLAST |
|
JmjC
|
1499 |
1722 |
2.43e-65 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000224065
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000225195
AA Change: C835S
PolyPhen 2
Score 0.160 (Sensitivity: 0.92; Specificity: 0.87)
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930433I11Rik |
C |
T |
7: 40,637,091 (GRCm39) |
|
probably benign |
Het |
| Abca13 |
T |
A |
11: 9,208,535 (GRCm39) |
L236Q |
probably damaging |
Het |
| Acp2 |
A |
T |
2: 91,038,391 (GRCm39) |
T255S |
probably benign |
Het |
| Acsf3 |
A |
C |
8: 123,544,131 (GRCm39) |
R536S |
probably benign |
Het |
| Adgrb1 |
T |
G |
15: 74,401,664 (GRCm39) |
V220G |
probably benign |
Het |
| Anks6 |
C |
T |
4: 47,030,795 (GRCm39) |
G601S |
probably damaging |
Het |
| Atp5f1b |
A |
G |
10: 127,919,854 (GRCm39) |
Q74R |
probably benign |
Het |
| Bltp1 |
A |
T |
3: 37,054,234 (GRCm39) |
M3118L |
probably benign |
Het |
| Brf1 |
G |
A |
12: 112,943,352 (GRCm39) |
T166M |
probably damaging |
Het |
| Capn9 |
A |
G |
8: 125,324,264 (GRCm39) |
K188R |
probably damaging |
Het |
| Casp8 |
A |
T |
1: 58,883,835 (GRCm39) |
N381Y |
possibly damaging |
Het |
| Ccdc88b |
A |
G |
19: 6,825,600 (GRCm39) |
S1218P |
probably damaging |
Het |
| Cdc42bpg |
C |
T |
19: 6,363,250 (GRCm39) |
P403S |
probably benign |
Het |
| Cdkal1 |
T |
A |
13: 30,030,222 (GRCm39) |
Y91F |
probably damaging |
Het |
| Cdyl2 |
T |
C |
8: 117,350,679 (GRCm39) |
N151D |
possibly damaging |
Het |
| Cnot1 |
T |
A |
8: 96,479,396 (GRCm39) |
R875S |
possibly damaging |
Het |
| Cpd |
A |
G |
11: 76,702,530 (GRCm39) |
S613P |
possibly damaging |
Het |
| Cyp2e1 |
G |
T |
7: 140,354,648 (GRCm39) |
R492L |
probably damaging |
Het |
| D5Ertd579e |
G |
A |
5: 36,760,047 (GRCm39) |
T1371M |
probably benign |
Het |
| Dcaf8 |
A |
G |
1: 172,014,476 (GRCm39) |
T394A |
probably benign |
Het |
| Dgka |
T |
C |
10: 128,571,702 (GRCm39) |
E117G |
probably damaging |
Het |
| Dock4 |
G |
A |
12: 40,894,440 (GRCm39) |
V1867I |
probably benign |
Het |
| E2f2 |
G |
T |
4: 135,914,248 (GRCm39) |
A333S |
probably benign |
Het |
| Eif3l |
T |
C |
15: 78,968,354 (GRCm39) |
S208P |
probably benign |
Het |
| Elovl3 |
A |
T |
19: 46,122,961 (GRCm39) |
H179L |
probably damaging |
Het |
| Eml5 |
T |
C |
12: 98,758,875 (GRCm39) |
D1766G |
probably damaging |
Het |
| Eno4 |
A |
G |
19: 58,934,023 (GRCm39) |
T75A |
probably benign |
Het |
| Fam135a |
C |
T |
1: 24,067,888 (GRCm39) |
D94N |
probably benign |
Het |
| Fasn |
G |
T |
11: 120,705,862 (GRCm39) |
Q1136K |
probably benign |
Het |
| Fcer1a |
T |
G |
1: 173,053,022 (GRCm39) |
N58T |
probably damaging |
Het |
| Frmd4b |
T |
A |
6: 97,272,941 (GRCm39) |
D763V |
probably damaging |
Het |
| Gm43518 |
A |
G |
5: 124,076,297 (GRCm39) |
T115A |
probably damaging |
Het |
| Gria4 |
C |
T |
9: 4,472,176 (GRCm39) |
E438K |
probably benign |
Het |
| Grin2d |
T |
C |
7: 45,503,692 (GRCm39) |
E681G |
probably damaging |
Het |
| Gtf3c5 |
G |
T |
2: 28,472,885 (GRCm39) |
N35K |
possibly damaging |
Het |
| Hydin |
A |
G |
8: 111,309,300 (GRCm39) |
T4031A |
probably benign |
Het |
| Igfn1 |
G |
T |
1: 135,892,564 (GRCm39) |
N2185K |
probably benign |
Het |
| Il17rb |
T |
C |
14: 29,724,333 (GRCm39) |
T174A |
probably benign |
Het |
| Lgi2 |
A |
T |
5: 52,695,429 (GRCm39) |
I510N |
probably damaging |
Het |
| Map3k6 |
A |
G |
4: 132,979,054 (GRCm39) |
E1164G |
probably benign |
Het |
| Mpv17l |
T |
A |
16: 13,758,537 (GRCm39) |
M1K |
probably null |
Het |
| Myoc |
T |
A |
1: 162,467,203 (GRCm39) |
L124Q |
probably damaging |
Het |
| Nbeal2 |
C |
A |
9: 110,455,796 (GRCm39) |
|
probably null |
Het |
| Nek10 |
A |
G |
14: 14,820,851 (GRCm38) |
K13E |
possibly damaging |
Het |
| Nt5dc2 |
A |
G |
14: 30,860,989 (GRCm39) |
H491R |
possibly damaging |
Het |
| Or4f61 |
A |
C |
2: 111,922,452 (GRCm39) |
M198R |
possibly damaging |
Het |
| Or51b6 |
T |
A |
7: 103,556,406 (GRCm39) |
Y250* |
probably null |
Het |
| Or8k21 |
T |
C |
2: 86,144,706 (GRCm39) |
Q308R |
probably benign |
Het |
| Pclo |
T |
A |
5: 14,727,322 (GRCm39) |
|
probably benign |
Het |
| Pgm2 |
A |
T |
5: 64,265,092 (GRCm39) |
N371I |
possibly damaging |
Het |
| Phf20l1 |
T |
A |
15: 66,508,762 (GRCm39) |
S873T |
possibly damaging |
Het |
| Plch1 |
T |
C |
3: 63,606,131 (GRCm39) |
T1249A |
probably benign |
Het |
| Plekhn1 |
A |
T |
4: 156,309,222 (GRCm39) |
I228N |
possibly damaging |
Het |
| Ppp1r12a |
A |
T |
10: 108,103,263 (GRCm39) |
|
probably null |
Het |
| Ptchd3 |
T |
C |
11: 121,721,972 (GRCm39) |
Y282H |
probably damaging |
Het |
| Ptprk |
T |
A |
10: 28,468,769 (GRCm39) |
N1396K |
probably damaging |
Het |
| Rap1gap2 |
T |
C |
11: 74,329,121 (GRCm39) |
E81G |
probably damaging |
Het |
| Rpf2 |
T |
C |
10: 40,122,971 (GRCm39) |
M1V |
probably null |
Het |
| Rpgrip1l |
G |
A |
8: 91,948,012 (GRCm39) |
Q1224* |
probably null |
Het |
| Rreb1 |
A |
G |
13: 38,112,254 (GRCm39) |
D286G |
probably benign |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Senp5 |
A |
T |
16: 31,807,960 (GRCm39) |
N431K |
probably benign |
Het |
| Serpina1f |
A |
C |
12: 103,659,809 (GRCm39) |
S158A |
probably damaging |
Het |
| Sertad3 |
T |
A |
7: 27,176,145 (GRCm39) |
I193N |
probably damaging |
Het |
| Slc22a8 |
T |
A |
19: 8,571,528 (GRCm39) |
N86K |
probably damaging |
Het |
| Slc6a2 |
T |
C |
8: 93,721,347 (GRCm39) |
V492A |
possibly damaging |
Het |
| Slf2 |
T |
A |
19: 44,940,523 (GRCm39) |
D773E |
probably benign |
Het |
| Slmap |
A |
C |
14: 26,184,744 (GRCm39) |
L272R |
probably damaging |
Het |
| Smyd5 |
T |
C |
6: 85,422,185 (GRCm39) |
|
probably benign |
Het |
| Snx21 |
G |
T |
2: 164,628,666 (GRCm39) |
R103L |
probably damaging |
Het |
| Sphk2 |
T |
A |
7: 45,361,777 (GRCm39) |
|
probably null |
Het |
| Stab1 |
T |
C |
14: 30,867,812 (GRCm39) |
K1653E |
probably benign |
Het |
| Syde1 |
A |
G |
10: 78,425,252 (GRCm39) |
V253A |
probably benign |
Het |
| Sympk |
G |
T |
7: 18,776,584 (GRCm39) |
R492L |
probably benign |
Het |
| Taar7f |
T |
C |
10: 23,925,451 (GRCm39) |
I15T |
probably benign |
Het |
| Tas2r140 |
A |
G |
6: 40,468,200 (GRCm39) |
D10G |
probably benign |
Het |
| Tbcc |
A |
G |
17: 47,202,600 (GRCm39) |
S329G |
probably benign |
Het |
| Teddm3 |
G |
A |
16: 20,971,900 (GRCm39) |
T223M |
probably benign |
Het |
| Tex14 |
G |
T |
11: 87,405,668 (GRCm39) |
C860F |
probably benign |
Het |
| Thada |
A |
T |
17: 84,751,896 (GRCm39) |
L360Q |
probably damaging |
Het |
| Thop1 |
C |
A |
10: 80,916,412 (GRCm39) |
H473Q |
probably damaging |
Het |
| Tln2 |
T |
C |
9: 67,163,310 (GRCm39) |
D1075G |
probably benign |
Het |
| Tmem130 |
G |
A |
5: 144,680,528 (GRCm39) |
T292I |
probably benign |
Het |
| Tmem198b |
T |
C |
10: 128,637,305 (GRCm39) |
N278S |
probably benign |
Het |
| Ttc21a |
A |
T |
9: 119,771,731 (GRCm39) |
T177S |
probably benign |
Het |
| Ubr2 |
A |
T |
17: 47,280,173 (GRCm39) |
C659S |
probably damaging |
Het |
| Vmn2r4 |
T |
C |
3: 64,298,373 (GRCm39) |
K585R |
probably benign |
Het |
| Vmn2r86 |
A |
G |
10: 130,282,456 (GRCm39) |
I720T |
probably damaging |
Het |
| Wdr35 |
G |
T |
12: 9,037,327 (GRCm39) |
W311L |
probably damaging |
Het |
| Zfp39 |
A |
T |
11: 58,782,028 (GRCm39) |
F245I |
possibly damaging |
Het |
| Zftraf1 |
A |
T |
15: 76,530,512 (GRCm39) |
F269L |
probably benign |
Het |
| Zmym5 |
G |
A |
14: 57,034,236 (GRCm39) |
T325I |
probably benign |
Het |
| Zng1 |
A |
T |
19: 24,898,383 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Kdm3b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00162:Kdm3b
|
APN |
18 |
34,942,462 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01357:Kdm3b
|
APN |
18 |
34,926,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01615:Kdm3b
|
APN |
18 |
34,962,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01980:Kdm3b
|
APN |
18 |
34,967,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Kdm3b
|
APN |
18 |
34,956,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02346:Kdm3b
|
APN |
18 |
34,967,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02417:Kdm3b
|
APN |
18 |
34,941,630 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02531:Kdm3b
|
APN |
18 |
34,928,782 (GRCm39) |
missense |
probably benign |
|
|
IGL02589:Kdm3b
|
APN |
18 |
34,945,471 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02793:Kdm3b
|
APN |
18 |
34,962,072 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03121:Kdm3b
|
APN |
18 |
34,928,762 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03123:Kdm3b
|
APN |
18 |
34,942,544 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03128:Kdm3b
|
APN |
18 |
34,960,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Affable
|
UTSW |
18 |
34,926,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Dotage
|
UTSW |
18 |
34,960,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Endearing
|
UTSW |
18 |
34,960,381 (GRCm39) |
splice site |
probably null |
|
|
Oldtimer
|
UTSW |
18 |
34,956,752 (GRCm39) |
nonsense |
probably null |
|
|
PIT4382001:Kdm3b
|
UTSW |
18 |
34,942,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4445001:Kdm3b
|
UTSW |
18 |
34,926,168 (GRCm39) |
nonsense |
probably null |
|
|
R0068:Kdm3b
|
UTSW |
18 |
34,957,827 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0068:Kdm3b
|
UTSW |
18 |
34,957,827 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0233:Kdm3b
|
UTSW |
18 |
34,942,473 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0265:Kdm3b
|
UTSW |
18 |
34,928,716 (GRCm39) |
splice site |
probably benign |
|
|
R0306:Kdm3b
|
UTSW |
18 |
34,937,070 (GRCm39) |
missense |
probably benign |
0.35 |
|
R0941:Kdm3b
|
UTSW |
18 |
34,936,605 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0970:Kdm3b
|
UTSW |
18 |
34,942,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1061:Kdm3b
|
UTSW |
18 |
34,929,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Kdm3b
|
UTSW |
18 |
34,952,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1221:Kdm3b
|
UTSW |
18 |
34,941,298 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1486:Kdm3b
|
UTSW |
18 |
34,967,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1523:Kdm3b
|
UTSW |
18 |
34,926,226 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1558:Kdm3b
|
UTSW |
18 |
34,942,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Kdm3b
|
UTSW |
18 |
34,942,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1601:Kdm3b
|
UTSW |
18 |
34,941,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1650:Kdm3b
|
UTSW |
18 |
34,942,168 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1772:Kdm3b
|
UTSW |
18 |
34,936,557 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1853:Kdm3b
|
UTSW |
18 |
34,966,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1934:Kdm3b
|
UTSW |
18 |
34,946,597 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1959:Kdm3b
|
UTSW |
18 |
34,945,448 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2079:Kdm3b
|
UTSW |
18 |
34,936,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2102:Kdm3b
|
UTSW |
18 |
34,963,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2121:Kdm3b
|
UTSW |
18 |
34,929,833 (GRCm39) |
splice site |
probably benign |
|
|
R2281:Kdm3b
|
UTSW |
18 |
34,941,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Kdm3b
|
UTSW |
18 |
34,941,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3755:Kdm3b
|
UTSW |
18 |
34,941,349 (GRCm39) |
missense |
probably benign |
|
|
R3857:Kdm3b
|
UTSW |
18 |
34,966,440 (GRCm39) |
missense |
probably benign |
|
|
R4165:Kdm3b
|
UTSW |
18 |
34,928,797 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4166:Kdm3b
|
UTSW |
18 |
34,928,797 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4372:Kdm3b
|
UTSW |
18 |
34,960,497 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4672:Kdm3b
|
UTSW |
18 |
34,941,630 (GRCm39) |
missense |
probably benign |
|
|
R4933:Kdm3b
|
UTSW |
18 |
34,943,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Kdm3b
|
UTSW |
18 |
34,955,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5009:Kdm3b
|
UTSW |
18 |
34,957,763 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5059:Kdm3b
|
UTSW |
18 |
34,910,250 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5270:Kdm3b
|
UTSW |
18 |
34,960,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5816:Kdm3b
|
UTSW |
18 |
34,961,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5970:Kdm3b
|
UTSW |
18 |
34,962,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6244:Kdm3b
|
UTSW |
18 |
34,926,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6705:Kdm3b
|
UTSW |
18 |
34,952,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6723:Kdm3b
|
UTSW |
18 |
34,926,058 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6909:Kdm3b
|
UTSW |
18 |
34,960,381 (GRCm39) |
splice site |
probably null |
|
|
R6958:Kdm3b
|
UTSW |
18 |
34,941,336 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7026:Kdm3b
|
UTSW |
18 |
34,955,517 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7289:Kdm3b
|
UTSW |
18 |
34,927,557 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7488:Kdm3b
|
UTSW |
18 |
34,957,934 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7587:Kdm3b
|
UTSW |
18 |
34,930,080 (GRCm39) |
splice site |
probably null |
|
|
R7695:Kdm3b
|
UTSW |
18 |
34,927,612 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7846:Kdm3b
|
UTSW |
18 |
34,942,293 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7984:Kdm3b
|
UTSW |
18 |
34,956,752 (GRCm39) |
nonsense |
probably null |
|
|
R7997:Kdm3b
|
UTSW |
18 |
34,941,336 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8035:Kdm3b
|
UTSW |
18 |
34,941,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8064:Kdm3b
|
UTSW |
18 |
34,946,460 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8141:Kdm3b
|
UTSW |
18 |
34,961,599 (GRCm39) |
nonsense |
probably null |
|
|
R8302:Kdm3b
|
UTSW |
18 |
34,967,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8328:Kdm3b
|
UTSW |
18 |
34,926,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8513:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8515:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8523:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8717:Kdm3b
|
UTSW |
18 |
34,952,840 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8725:Kdm3b
|
UTSW |
18 |
34,960,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8727:Kdm3b
|
UTSW |
18 |
34,960,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8762:Kdm3b
|
UTSW |
18 |
34,937,157 (GRCm39) |
missense |
probably benign |
|
|
R8835:Kdm3b
|
UTSW |
18 |
34,941,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8918:Kdm3b
|
UTSW |
18 |
34,970,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Kdm3b
|
UTSW |
18 |
34,963,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9144:Kdm3b
|
UTSW |
18 |
34,927,558 (GRCm39) |
missense |
probably benign |
|
|
R9246:Kdm3b
|
UTSW |
18 |
34,941,480 (GRCm39) |
nonsense |
probably null |
|
|
R9376:Kdm3b
|
UTSW |
18 |
34,970,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0028:Kdm3b
|
UTSW |
18 |
34,932,319 (GRCm39) |
splice site |
probably null |
|
|
X0067:Kdm3b
|
UTSW |
18 |
34,956,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Kdm3b
|
UTSW |
18 |
34,942,122 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CGACAACACTCGGCTATTTG -3'
(R):5'- TTCAGAGGGACATAAGCGTC -3'
Sequencing Primer
(F):5'- GACAACACTCGGCTATTTGTTTCTC -3'
(R):5'- TCCAACTGCCAATGCCTACTATC -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation