Incidental Mutation 'R5068:Cep152'
| ID |
388411 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep152
|
| Ensembl Gene |
ENSMUSG00000068394 |
| Gene Name |
centrosomal protein 152 |
| Synonyms |
|
| MMRRC Submission |
042658-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5068 (G1)
|
| Quality Score |
177 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
125405008-125467033 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 125413736 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 1199
(I1199V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000087208
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000089776]
|
| AlphaFold |
A2AUM9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089776
AA Change: I1199V
PolyPhen 2
Score 0.253 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000087208
Gene: ENSMUSG00000068394
AA Change: I1199V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
106 |
124 |
N/A |
INTRINSIC |
|
coiled coil region
|
228 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
582 |
593 |
N/A |
INTRINSIC |
|
coiled coil region
|
602 |
651 |
N/A |
INTRINSIC |
|
coiled coil region
|
692 |
770 |
N/A |
INTRINSIC |
|
low complexity region
|
780 |
793 |
N/A |
INTRINSIC |
|
coiled coil region
|
835 |
868 |
N/A |
INTRINSIC |
|
coiled coil region
|
954 |
1038 |
N/A |
INTRINSIC |
|
coiled coil region
|
1205 |
1277 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
PHENOTYPE: Embryos homozygous for a null allele exhibit reduced numbers of centrosomes and cilia, increased apoptosis, and midgestation lethality. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 110 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,383,749 (GRCm39) |
S739P |
possibly damaging |
Het |
| 6030468B19Rik |
A |
G |
11: 117,693,701 (GRCm39) |
Y56C |
possibly damaging |
Het |
| Actn2 |
A |
G |
13: 12,303,408 (GRCm39) |
I464T |
possibly damaging |
Het |
| Add2 |
T |
A |
6: 86,084,440 (GRCm39) |
L496Q |
probably damaging |
Het |
| Akt1s1 |
T |
C |
7: 44,499,432 (GRCm39) |
|
probably null |
Het |
| Als2 |
G |
T |
1: 59,250,433 (GRCm39) |
P437Q |
probably benign |
Het |
| Ankar |
T |
C |
1: 72,719,369 (GRCm39) |
|
probably null |
Het |
| Ankrd17 |
T |
C |
5: 90,402,667 (GRCm39) |
R1464G |
probably damaging |
Het |
| Ankrd24 |
T |
C |
10: 81,475,699 (GRCm39) |
S121P |
possibly damaging |
Het |
| Arvcf |
A |
G |
16: 18,217,736 (GRCm39) |
Y412C |
probably damaging |
Het |
| Birc6 |
C |
T |
17: 74,872,967 (GRCm39) |
R409C |
probably damaging |
Het |
| Bnip3l |
T |
C |
14: 67,237,081 (GRCm39) |
E57G |
possibly damaging |
Het |
| Calcoco1 |
A |
G |
15: 102,619,527 (GRCm39) |
L354P |
probably damaging |
Het |
| Cc2d1b |
T |
C |
4: 108,480,661 (GRCm39) |
V27A |
possibly damaging |
Het |
| Cdc37 |
T |
C |
9: 21,061,099 (GRCm39) |
T19A |
probably damaging |
Het |
| Chd6 |
G |
T |
2: 160,808,289 (GRCm39) |
L1642I |
possibly damaging |
Het |
| Chst13 |
T |
C |
6: 90,286,551 (GRCm39) |
E137G |
possibly damaging |
Het |
| Cnrip1 |
A |
G |
11: 17,004,687 (GRCm39) |
D79G |
probably damaging |
Het |
| Dars2 |
A |
T |
1: 160,869,483 (GRCm39) |
C589S |
probably benign |
Het |
| Dhx15 |
T |
G |
5: 52,327,409 (GRCm39) |
I102L |
possibly damaging |
Het |
| Dip2a |
A |
G |
10: 76,153,877 (GRCm39) |
L151P |
possibly damaging |
Het |
| Dlc1 |
T |
C |
8: 37,405,184 (GRCm39) |
T202A |
probably benign |
Het |
| Dlg1 |
G |
T |
16: 31,503,113 (GRCm39) |
|
probably null |
Het |
| Dlgap4 |
T |
C |
2: 156,549,031 (GRCm39) |
F464L |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,632,013 (GRCm39) |
H1314R |
probably benign |
Het |
| Dsp |
A |
C |
13: 38,381,099 (GRCm39) |
T2615P |
possibly damaging |
Het |
| Dthd1 |
C |
A |
5: 62,976,059 (GRCm39) |
D244E |
probably benign |
Het |
| Dtl |
A |
T |
1: 191,300,485 (GRCm39) |
D126E |
probably damaging |
Het |
| Ell2 |
A |
G |
13: 75,911,737 (GRCm39) |
N341S |
probably benign |
Het |
| Enpp2 |
T |
C |
15: 54,727,450 (GRCm39) |
Y513C |
probably damaging |
Het |
| Erbb4 |
A |
T |
1: 68,083,061 (GRCm39) |
|
probably null |
Het |
| Erc2 |
A |
T |
14: 28,024,900 (GRCm39) |
H593L |
possibly damaging |
Het |
| Ercc6 |
T |
C |
14: 32,292,020 (GRCm39) |
V1128A |
probably benign |
Het |
| Fyn |
A |
G |
10: 39,402,839 (GRCm39) |
K204E |
probably damaging |
Het |
| Gm4847 |
A |
T |
1: 166,465,953 (GRCm39) |
F212Y |
possibly damaging |
Het |
| Gpc5 |
T |
C |
14: 115,654,676 (GRCm39) |
*499R |
probably null |
Het |
| Hcn4 |
T |
C |
9: 58,767,304 (GRCm39) |
L955P |
unknown |
Het |
| Hook2 |
C |
A |
8: 85,720,028 (GRCm39) |
L111I |
possibly damaging |
Het |
| Hook3 |
C |
T |
8: 26,585,785 (GRCm39) |
|
probably null |
Het |
| Hvcn1 |
T |
C |
5: 122,371,544 (GRCm39) |
F28S |
probably damaging |
Het |
| Igkv6-32 |
A |
G |
6: 70,051,267 (GRCm39) |
F30L |
possibly damaging |
Het |
| Inpp5b |
G |
A |
4: 124,636,442 (GRCm39) |
|
probably null |
Het |
| Itgb2 |
G |
A |
10: 77,384,595 (GRCm39) |
A239T |
probably damaging |
Het |
| Kcnrg |
T |
C |
14: 61,845,266 (GRCm39) |
L102P |
probably damaging |
Het |
| Kif16b |
A |
T |
2: 142,553,627 (GRCm39) |
M1068K |
probably benign |
Het |
| Kifc3 |
T |
C |
8: 95,836,844 (GRCm39) |
R109G |
possibly damaging |
Het |
| Klhl28 |
A |
T |
12: 65,004,486 (GRCm39) |
M9K |
probably benign |
Het |
| Kptn |
T |
C |
7: 15,857,027 (GRCm39) |
Y172H |
probably damaging |
Het |
| Mib1 |
A |
G |
18: 10,793,002 (GRCm39) |
E646G |
probably damaging |
Het |
| Mmp14 |
T |
A |
14: 54,676,570 (GRCm39) |
Y372N |
probably damaging |
Het |
| Mrc1 |
T |
A |
2: 14,311,327 (GRCm39) |
M868K |
probably benign |
Het |
| Mterf1a |
T |
C |
5: 3,941,854 (GRCm39) |
N5D |
probably benign |
Het |
| Muc5b |
T |
C |
7: 141,412,345 (GRCm39) |
S1764P |
unknown |
Het |
| Myo9b |
T |
C |
8: 71,801,699 (GRCm39) |
Y1275H |
probably damaging |
Het |
| Nek1 |
T |
C |
8: 61,469,330 (GRCm39) |
I129T |
probably damaging |
Het |
| Net1 |
G |
A |
13: 3,936,740 (GRCm39) |
A221V |
probably benign |
Het |
| Nuak2 |
A |
T |
1: 132,259,509 (GRCm39) |
D429V |
probably benign |
Het |
| Nup98 |
T |
C |
7: 101,794,862 (GRCm39) |
T882A |
probably benign |
Het |
| Or11g2 |
T |
A |
14: 50,856,197 (GRCm39) |
C173S |
probably damaging |
Het |
| Or11h4 |
C |
A |
14: 50,974,531 (GRCm39) |
L29F |
probably benign |
Het |
| Or52ab4 |
A |
T |
7: 102,987,229 (GRCm39) |
|
probably null |
Het |
| Or52h1 |
T |
A |
7: 103,829,448 (GRCm39) |
S56C |
probably damaging |
Het |
| Or8b42 |
T |
C |
9: 38,341,760 (GRCm39) |
Y61H |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Pcdh7 |
T |
C |
5: 57,879,508 (GRCm39) |
V1021A |
probably damaging |
Het |
| Pclo |
G |
C |
5: 14,729,087 (GRCm39) |
|
probably benign |
Het |
| Pds5a |
A |
C |
5: 65,772,615 (GRCm39) |
D1329E |
probably damaging |
Het |
| Pex5 |
A |
G |
6: 124,390,555 (GRCm39) |
S97P |
probably benign |
Het |
| Pias3 |
A |
G |
3: 96,611,171 (GRCm39) |
K431E |
probably damaging |
Het |
| Piwil1 |
T |
C |
5: 128,818,678 (GRCm39) |
S158P |
probably damaging |
Het |
| Plxnc1 |
A |
T |
10: 94,635,239 (GRCm39) |
I1329N |
possibly damaging |
Het |
| Pnkp |
C |
T |
7: 44,511,827 (GRCm39) |
S113L |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 29,098,397 (GRCm39) |
|
probably null |
Het |
| Prdm10 |
T |
C |
9: 31,270,343 (GRCm39) |
Y827H |
probably damaging |
Het |
| Prss3b |
A |
C |
6: 41,009,370 (GRCm39) |
Y155D |
probably benign |
Het |
| Psma2 |
G |
A |
13: 14,790,613 (GRCm39) |
V20I |
probably benign |
Het |
| Pwwp4a |
T |
C |
X: 72,171,577 (GRCm39) |
I323T |
probably damaging |
Het |
| Rgl3 |
A |
G |
9: 21,899,340 (GRCm39) |
|
probably null |
Het |
| Rnf17 |
T |
C |
14: 56,743,385 (GRCm39) |
V1317A |
probably damaging |
Het |
| Rpp40 |
T |
C |
13: 36,082,681 (GRCm39) |
N254D |
probably benign |
Het |
| Scin |
T |
A |
12: 40,174,699 (GRCm39) |
H128L |
probably damaging |
Het |
| Sh3bp2 |
A |
T |
5: 34,714,311 (GRCm39) |
M225L |
probably benign |
Het |
| Shisa9 |
C |
A |
16: 12,085,412 (GRCm39) |
H324Q |
possibly damaging |
Het |
| Sipa1l1 |
A |
G |
12: 82,484,601 (GRCm39) |
D1585G |
probably damaging |
Het |
| Slc11a1 |
G |
A |
1: 74,424,343 (GRCm39) |
A434T |
probably damaging |
Het |
| Slc5a8 |
A |
T |
10: 88,722,460 (GRCm39) |
I98F |
possibly damaging |
Het |
| Slc6a13 |
T |
C |
6: 121,310,301 (GRCm39) |
L320P |
probably damaging |
Het |
| Spats2l |
A |
G |
1: 57,982,380 (GRCm39) |
T421A |
probably benign |
Het |
| Spryd3 |
A |
T |
15: 102,037,046 (GRCm39) |
D207E |
probably benign |
Het |
| Srrt |
T |
C |
5: 137,294,803 (GRCm39) |
N392S |
possibly damaging |
Het |
| Stk36 |
G |
T |
1: 74,661,504 (GRCm39) |
R510S |
probably benign |
Het |
| Sucnr1 |
A |
G |
3: 59,994,288 (GRCm39) |
Y272C |
probably damaging |
Het |
| Taar7b |
T |
G |
10: 23,876,359 (GRCm39) |
S175A |
probably benign |
Het |
| Tmem131 |
A |
G |
1: 36,893,986 (GRCm39) |
I139T |
probably damaging |
Het |
| Tph2 |
T |
A |
10: 114,987,079 (GRCm39) |
Y237F |
probably benign |
Het |
| Trim35 |
C |
T |
14: 66,546,421 (GRCm39) |
|
probably benign |
Het |
| Tsc22d1 |
T |
C |
14: 76,655,750 (GRCm39) |
I661T |
probably benign |
Het |
| Ttc27 |
T |
A |
17: 75,106,337 (GRCm39) |
H541Q |
probably damaging |
Het |
| Uap1 |
G |
T |
1: 169,989,032 (GRCm39) |
P130Q |
probably damaging |
Het |
| Ube3c |
T |
C |
5: 29,806,352 (GRCm39) |
|
probably null |
Het |
| Umad1 |
A |
T |
6: 8,401,157 (GRCm39) |
|
probably null |
Het |
| Usp34 |
T |
C |
11: 23,410,665 (GRCm39) |
V2705A |
possibly damaging |
Het |
| Vps13a |
T |
C |
19: 16,723,422 (GRCm39) |
S259G |
probably benign |
Het |
| Vwa7 |
G |
A |
17: 35,243,166 (GRCm39) |
V615I |
probably benign |
Het |
| Wdfy3 |
T |
C |
5: 102,042,803 (GRCm39) |
T1983A |
probably benign |
Het |
| Wdr24 |
T |
G |
17: 26,044,753 (GRCm39) |
F203V |
possibly damaging |
Het |
| Xlr4c |
T |
A |
X: 72,282,290 (GRCm39) |
K121M |
probably damaging |
Het |
| Zfc3h1 |
T |
A |
10: 115,254,688 (GRCm39) |
C1427* |
probably null |
Het |
| Zfp282 |
A |
C |
6: 47,854,637 (GRCm39) |
Q11P |
probably benign |
Het |
| Zfp750 |
T |
A |
11: 121,403,021 (GRCm39) |
T576S |
probably benign |
Het |
|
| Other mutations in Cep152 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00155:Cep152
|
APN |
2 |
125,405,808 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00561:Cep152
|
APN |
2 |
125,405,643 (GRCm39) |
nonsense |
probably null |
|
|
IGL01082:Cep152
|
APN |
2 |
125,411,465 (GRCm39) |
splice site |
probably benign |
|
|
IGL01420:Cep152
|
APN |
2 |
125,405,572 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL01832:Cep152
|
APN |
2 |
125,460,414 (GRCm39) |
nonsense |
probably null |
|
|
IGL02106:Cep152
|
APN |
2 |
125,444,856 (GRCm39) |
splice site |
probably null |
|
|
IGL02124:Cep152
|
APN |
2 |
125,405,381 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL02349:Cep152
|
APN |
2 |
125,436,876 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02541:Cep152
|
APN |
2 |
125,447,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02659:Cep152
|
APN |
2 |
125,421,469 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02711:Cep152
|
APN |
2 |
125,405,862 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02737:Cep152
|
APN |
2 |
125,428,394 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL03060:Cep152
|
APN |
2 |
125,461,907 (GRCm39) |
splice site |
probably benign |
|
|
IGL03095:Cep152
|
APN |
2 |
125,460,371 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03186:Cep152
|
APN |
2 |
125,405,895 (GRCm39) |
missense |
probably benign |
|
|
IGL03306:Cep152
|
APN |
2 |
125,447,328 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0034:Cep152
|
UTSW |
2 |
125,425,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0034:Cep152
|
UTSW |
2 |
125,425,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0079:Cep152
|
UTSW |
2 |
125,460,373 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0244:Cep152
|
UTSW |
2 |
125,406,134 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0390:Cep152
|
UTSW |
2 |
125,418,789 (GRCm39) |
splice site |
probably benign |
|
|
R0462:Cep152
|
UTSW |
2 |
125,425,854 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0480:Cep152
|
UTSW |
2 |
125,423,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0595:Cep152
|
UTSW |
2 |
125,436,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Cep152
|
UTSW |
2 |
125,436,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0973:Cep152
|
UTSW |
2 |
125,436,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1634:Cep152
|
UTSW |
2 |
125,425,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Cep152
|
UTSW |
2 |
125,408,174 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1693:Cep152
|
UTSW |
2 |
125,408,174 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1887:Cep152
|
UTSW |
2 |
125,462,225 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1930:Cep152
|
UTSW |
2 |
125,460,291 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2178:Cep152
|
UTSW |
2 |
125,421,954 (GRCm39) |
splice site |
probably null |
|
|
R2225:Cep152
|
UTSW |
2 |
125,423,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2324:Cep152
|
UTSW |
2 |
125,405,382 (GRCm39) |
missense |
probably benign |
0.38 |
|
R2416:Cep152
|
UTSW |
2 |
125,406,092 (GRCm39) |
nonsense |
probably null |
|
|
R2845:Cep152
|
UTSW |
2 |
125,429,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3753:Cep152
|
UTSW |
2 |
125,466,972 (GRCm39) |
unclassified |
probably benign |
|
|
R4212:Cep152
|
UTSW |
2 |
125,461,921 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4304:Cep152
|
UTSW |
2 |
125,405,643 (GRCm39) |
nonsense |
probably null |
|
|
R4371:Cep152
|
UTSW |
2 |
125,454,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4399:Cep152
|
UTSW |
2 |
125,429,900 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4536:Cep152
|
UTSW |
2 |
125,444,867 (GRCm39) |
splice site |
probably null |
|
|
R4713:Cep152
|
UTSW |
2 |
125,429,868 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4777:Cep152
|
UTSW |
2 |
125,406,015 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4779:Cep152
|
UTSW |
2 |
125,410,812 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4785:Cep152
|
UTSW |
2 |
125,428,249 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4816:Cep152
|
UTSW |
2 |
125,405,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4847:Cep152
|
UTSW |
2 |
125,460,394 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R4898:Cep152
|
UTSW |
2 |
125,428,301 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4934:Cep152
|
UTSW |
2 |
125,453,016 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4997:Cep152
|
UTSW |
2 |
125,428,271 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5183:Cep152
|
UTSW |
2 |
125,408,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5198:Cep152
|
UTSW |
2 |
125,429,544 (GRCm39) |
missense |
probably benign |
|
|
R5261:Cep152
|
UTSW |
2 |
125,406,125 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5272:Cep152
|
UTSW |
2 |
125,452,950 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5284:Cep152
|
UTSW |
2 |
125,421,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Cep152
|
UTSW |
2 |
125,405,552 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6155:Cep152
|
UTSW |
2 |
125,423,620 (GRCm39) |
missense |
probably benign |
|
|
R6239:Cep152
|
UTSW |
2 |
125,421,332 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6590:Cep152
|
UTSW |
2 |
125,406,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6690:Cep152
|
UTSW |
2 |
125,406,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6754:Cep152
|
UTSW |
2 |
125,429,588 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6798:Cep152
|
UTSW |
2 |
125,408,447 (GRCm39) |
splice site |
probably null |
|
|
R6816:Cep152
|
UTSW |
2 |
125,436,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6977:Cep152
|
UTSW |
2 |
125,410,742 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7125:Cep152
|
UTSW |
2 |
125,408,593 (GRCm39) |
nonsense |
probably null |
|
|
R7146:Cep152
|
UTSW |
2 |
125,456,325 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7588:Cep152
|
UTSW |
2 |
125,411,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Cep152
|
UTSW |
2 |
125,432,033 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7883:Cep152
|
UTSW |
2 |
125,454,978 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8047:Cep152
|
UTSW |
2 |
125,406,247 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8082:Cep152
|
UTSW |
2 |
125,428,313 (GRCm39) |
missense |
probably benign |
|
|
R8680:Cep152
|
UTSW |
2 |
125,406,131 (GRCm39) |
nonsense |
probably null |
|
|
R8739:Cep152
|
UTSW |
2 |
125,461,975 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8744:Cep152
|
UTSW |
2 |
125,436,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8896:Cep152
|
UTSW |
2 |
125,408,155 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8924:Cep152
|
UTSW |
2 |
125,444,778 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8971:Cep152
|
UTSW |
2 |
125,421,770 (GRCm39) |
nonsense |
probably null |
|
|
R9004:Cep152
|
UTSW |
2 |
125,453,020 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9149:Cep152
|
UTSW |
2 |
125,463,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9149:Cep152
|
UTSW |
2 |
125,461,803 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9161:Cep152
|
UTSW |
2 |
125,408,574 (GRCm39) |
nonsense |
probably null |
|
|
R9239:Cep152
|
UTSW |
2 |
125,425,830 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9249:Cep152
|
UTSW |
2 |
125,405,904 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9258:Cep152
|
UTSW |
2 |
125,421,356 (GRCm39) |
nonsense |
probably null |
|
|
R9619:Cep152
|
UTSW |
2 |
125,436,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9643:Cep152
|
UTSW |
2 |
125,406,150 (GRCm39) |
nonsense |
probably null |
|
|
R9775:Cep152
|
UTSW |
2 |
125,423,660 (GRCm39) |
nonsense |
probably null |
|
|
X0009:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0010:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0011:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0014:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0017:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0021:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Cep152
|
UTSW |
2 |
125,461,983 (GRCm39) |
missense |
probably benign |
0.07 |
|
X0023:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0033:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0064:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0067:Cep152
|
UTSW |
2 |
125,456,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cep152
|
UTSW |
2 |
125,425,891 (GRCm39) |
missense |
probably benign |
0.23 |
|
Z1177:Cep152
|
UTSW |
2 |
125,461,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cep152
|
UTSW |
2 |
125,456,244 (GRCm39) |
missense |
probably benign |
0.33 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTTTTCAGCCAGGATCCG -3'
(R):5'- ATGGAGGCTAAGAAACCATCC -3'
Sequencing Primer
(F):5'- GATCCGCCAGCCTCCTAC -3'
(R):5'- CATCCAGCAAATCGTGGGACTG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation