Mutagenetix > Incidental Mutation

Incidental Mutation 'R0432:Usp34'

38846

Institutional Source

Beutler Lab

Gene Symbol

Usp34

Ensembl Gene

ENSMUSG00000056342

Gene Name

ubiquitin specific peptidase 34

Synonyms

Murr2, A530081C03Rik

MMRRC Submission

038634-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.831) question?

Stock #

R0432 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

23306895-23490560 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 23401505 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Aspartic acid at position 1431 (V1431D)

Ref Sequence

ENSEMBL: ENSMUSP00000137430 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000180046]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000137823
AA Change: V1450D

SMART Domains

Protein: ENSMUSP00000120747
Gene: ENSMUSG00000056342
AA Change: V1450D

Domain	Start	End	E-Value	Type
low complexity region	489	500	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	591	610	N/A	INTRINSIC
coiled coil region	626	671	N/A	INTRINSIC
low complexity region	827	842	N/A	INTRINSIC
low complexity region	1207	1218	N/A	INTRINSIC
low complexity region	1399	1410	N/A	INTRINSIC
low complexity region	1518	1532	N/A	INTRINSIC
low complexity region	1751	1764	N/A	INTRINSIC
low complexity region	1812	1824	N/A	INTRINSIC
Pfam:UCH	1950	2293	7.6e-44	PFAM
Pfam:UCH_1	1951	2249	3.6e-22	PFAM
low complexity region	2542	2564	N/A	INTRINSIC
low complexity region	2672	2679	N/A	INTRINSIC
Blast:Drf_GBD	2943	3116	3e-53	BLAST
low complexity region	3344	3357	N/A	INTRINSIC
coiled coil region	3371	3393	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000180046
AA Change: V1431D

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000137430
Gene: ENSMUSG00000056342
AA Change: V1431D

Domain	Start	End	E-Value	Type
low complexity region	469	480	N/A	INTRINSIC
low complexity region	510	524	N/A	INTRINSIC
low complexity region	571	590	N/A	INTRINSIC
coiled coil region	607	652	N/A	INTRINSIC
low complexity region	807	822	N/A	INTRINSIC
low complexity region	1187	1198	N/A	INTRINSIC
low complexity region	1379	1390	N/A	INTRINSIC
low complexity region	1498	1512	N/A	INTRINSIC
low complexity region	1731	1744	N/A	INTRINSIC
low complexity region	1792	1804	N/A	INTRINSIC
Pfam:UCH	1930	2273	2.3e-44	PFAM
Pfam:UCH_1	1931	2229	1.1e-22	PFAM
low complexity region	2522	2544	N/A	INTRINSIC
low complexity region	2652	2659	N/A	INTRINSIC
Blast:Drf_GBD	2923	3096	2e-53	BLAST
low complexity region	3324	3337	N/A	INTRINSIC
coiled coil region	3352	3374	N/A	INTRINSIC

Meta Mutation Damage Score

0.9308

Coding Region Coverage

1x: 99.2%
3x: 98.3%
10x: 96.3%
20x: 92.9%

Validation Efficiency

99% (91/92)

Allele List at MGI

Other mutations in this stock

Total: 88 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310061I04Rik	A	G	17: 35,895,816 (GRCm38)	L110P	probably damaging	Het
4930522L14Rik	A	T	5: 109,736,919 (GRCm38)	C358S	probably damaging	Het
Abca8b	C	A	11: 109,980,015 (GRCm38)	V104F	possibly damaging	Het
Afap1l2	T	C	19: 56,917,119 (GRCm38)		probably benign	Het
Ahctf1	A	C	1: 179,784,161 (GRCm38)	I548R	probably damaging	Het
Alox12b	G	T	11: 69,169,556 (GRCm38)	G646V	probably damaging	Het
Aoah	C	T	13: 20,911,198 (GRCm38)		probably benign	Het
Arhgap39	C	T	15: 76,734,886 (GRCm38)	D833N	probably damaging	Het
Atxn1l	A	G	8: 109,731,693 (GRCm38)	W646R	probably damaging	Het
Cabp2	T	C	19: 4,084,903 (GRCm38)	I28T	possibly damaging	Het
Cacna1b	G	A	2: 24,687,704 (GRCm38)	T719I	probably damaging	Het
Camk1d	A	T	2: 5,445,135 (GRCm38)	H70Q	probably damaging	Het
Car1	T	C	3: 14,770,176 (GRCm38)	T170A	probably benign	Het
Ccdc162	T	C	10: 41,541,860 (GRCm38)	T2113A	probably benign	Het
Cdc5l	G	A	17: 45,415,684 (GRCm38)	R321W	probably damaging	Het
Cdh17	T	A	4: 11,771,273 (GRCm38)	C18*	probably null	Het
Cdk17	A	T	10: 93,237,790 (GRCm38)		probably benign	Het
Chd9	T	A	8: 90,994,450 (GRCm38)		probably benign	Het
Chrm5	T	A	2: 112,479,655 (GRCm38)	K372M	possibly damaging	Het
Clasp2	A	G	9: 113,909,419 (GRCm38)	T423A	probably benign	Het
Col11a1	A	G	3: 114,205,901 (GRCm38)		probably benign	Het
Col27a1	T	C	4: 63,225,611 (GRCm38)	M512T	possibly damaging	Het
Dclk3	A	G	9: 111,484,935 (GRCm38)	D693G	probably damaging	Het
Dcun1d3	T	A	7: 119,857,950 (GRCm38)	K180*	probably null	Het
Dmxl2	T	C	9: 54,416,951 (GRCm38)	R876G	probably benign	Het
Dnmbp	A	T	19: 43,854,857 (GRCm38)	Y432*	probably null	Het
Elapor2	G	T	5: 9,440,966 (GRCm38)	G659*	probably null	Het
Eml2	C	T	7: 19,179,531 (GRCm38)	Q125*	probably null	Het
Faap100	A	C	11: 120,373,876 (GRCm38)		probably benign	Het
Foxp2	T	C	6: 15,254,279 (GRCm38)		probably benign	Het
Gda	A	G	19: 21,417,107 (GRCm38)	Y129H	probably damaging	Het
Gga3	G	A	11: 115,590,524 (GRCm38)	R207C	probably damaging	Het
Glg1	T	C	8: 111,182,569 (GRCm38)	I496M	probably damaging	Het
Glt6d1	C	A	2: 25,794,727 (GRCm38)		probably null	Het
Gm10322	A	T	10: 59,616,208 (GRCm38)	H49L	possibly damaging	Het
Golga5	G	T	12: 102,476,208 (GRCm38)	V269F	possibly damaging	Het
Gramd2b	G	A	18: 56,474,069 (GRCm38)	C85Y	probably benign	Het
Grhl1	C	T	12: 24,582,919 (GRCm38)	P153L	probably benign	Het
Hdac9	T	C	12: 34,437,222 (GRCm38)	Q60R	probably damaging	Het
Hdlbp	T	C	1: 93,425,332 (GRCm38)	I414V	probably damaging	Het
Itpk1	C	T	12: 102,606,078 (GRCm38)		probably benign	Het
Itsn1	T	A	16: 91,815,520 (GRCm38)	Y266N	probably damaging	Het
Lipe	G	A	7: 25,398,488 (GRCm38)	P10L	probably benign	Het
Lrrc8a	A	G	2: 30,257,067 (GRCm38)	E631G	probably damaging	Het
Lvrn	T	A	18: 46,905,299 (GRCm38)	N973K	possibly damaging	Het
Man2c1	T	A	9: 57,135,597 (GRCm38)	H250Q	probably damaging	Het
Mup3	T	C	4: 62,085,282 (GRCm38)	T117A	probably benign	Het
Myo6	A	C	9: 80,273,974 (GRCm38)		probably benign	Het
Nbn	T	A	4: 15,983,951 (GRCm38)		probably benign	Het
Ncapg	T	A	5: 45,672,428 (GRCm38)	N157K	probably damaging	Het
Or4p7	C	T	2: 88,392,033 (GRCm38)	T262I	probably damaging	Het
Or5an1	T	A	19: 12,283,903 (GRCm38)	M285K	probably damaging	Het
Or5m12	T	A	2: 85,904,157 (GRCm38)	N299I	probably damaging	Het
Or5w14	G	A	2: 87,711,430 (GRCm38)	H159Y	probably benign	Het
Or9m1	T	C	2: 87,902,960 (GRCm38)	T239A	probably damaging	Het
P4ha1	T	A	10: 59,348,257 (GRCm38)	Y180*	probably null	Het
Pcdhb19	T	A	18: 37,499,535 (GRCm38)	F794L	probably benign	Het
Pdxdc1	T	A	16: 13,854,400 (GRCm38)	I379F	probably damaging	Het
Psme3	T	A	11: 101,320,442 (GRCm38)	S185T	possibly damaging	Het
Ptgr1	A	G	4: 58,978,045 (GRCm38)	S116P	probably damaging	Het
Ptpn23	A	T	9: 110,389,010 (GRCm38)		probably null	Het
Rabgap1l	A	C	1: 160,722,205 (GRCm38)	I277R	probably benign	Het
Rapgef1	C	T	2: 29,679,816 (GRCm38)	T93I	possibly damaging	Het
Rbp3	A	T	14: 33,954,773 (GRCm38)	D226V	probably damaging	Het
Rnf144a	A	T	12: 26,339,329 (GRCm38)	C38S	probably damaging	Het
Rptor	C	T	11: 119,780,553 (GRCm38)	Q281*	probably null	Het
Rragd	T	C	4: 33,004,332 (GRCm38)	L208S	probably damaging	Het
Slc12a4	T	C	8: 105,959,488 (GRCm38)	E41G	probably damaging	Het
Slc16a1	G	T	3: 104,653,419 (GRCm38)	V347F	probably benign	Het
Slit1	G	A	19: 41,743,293 (GRCm38)	T39I	probably damaging	Het
Sra1	T	C	18: 36,677,503 (GRCm38)	N98S	probably benign	Het
Ssx2ip	T	C	3: 146,426,429 (GRCm38)	L215P	probably damaging	Het
Syne2	A	T	12: 75,949,064 (GRCm38)	H2126L	probably damaging	Het
Tep1	TTTCTTCTTCTT	TTTCTTCTT	14: 50,866,823 (GRCm38)		probably benign	Het
Tgfbi	T	C	13: 56,632,191 (GRCm38)		probably benign	Het
Tmem232	T	C	17: 65,256,503 (GRCm38)	M632V	probably damaging	Het
Tmem81	C	G	1: 132,507,829 (GRCm38)	I124M	probably damaging	Het
Tnnt3	T	G	7: 142,512,086 (GRCm38)	D153E	probably benign	Het
Tnrc6b	T	A	15: 80,923,446 (GRCm38)		probably benign	Het
Tpsab1	A	G	17: 25,343,824 (GRCm38)		probably benign	Het
Wdr49	G	T	3: 75,450,022 (GRCm38)	R285S	possibly damaging	Het
Wdr7	A	G	18: 63,796,249 (GRCm38)	Y1052C	probably damaging	Het
Zan	A	T	5: 137,382,316 (GRCm38)		probably benign	Het
Zfp652	G	A	11: 95,763,739 (GRCm38)	V323I	possibly damaging	Het
Zfp740	A	G	15: 102,212,659 (GRCm38)	T136A	possibly damaging	Het
Zfp82	C	T	7: 30,056,329 (GRCm38)	E443K	probably damaging	Het
Zfp874b	A	G	13: 67,481,836 (GRCm38)	S10P	probably damaging	Het
Zmynd19	A	G	2: 24,958,122 (GRCm38)	Y110C	probably benign	Het

Other mutations in Usp34

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00092:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL00477:Usp34	APN	11	23,468,879 (GRCm38)	missense	probably damaging	0.99
IGL01307:Usp34	APN	11	23,417,676 (GRCm38)	missense	probably damaging	0.99
IGL01313:Usp34	APN	11	23,473,206 (GRCm38)	missense	probably damaging	1.00
IGL01794:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01826:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01827:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01830:Usp34	APN	11	23,436,020 (GRCm38)	missense	probably damaging	0.98
IGL01867:Usp34	APN	11	23,384,411 (GRCm38)	missense	possibly damaging	0.77
IGL01939:Usp34	APN	11	23,345,141 (GRCm38)	splice site	probably benign
IGL01977:Usp34	APN	11	23,452,661 (GRCm38)	missense	probably damaging	1.00
IGL01985:Usp34	APN	11	23,452,565 (GRCm38)	missense	probably damaging	1.00
IGL02011:Usp34	APN	11	23,471,554 (GRCm38)	missense	probably damaging	0.99
IGL02302:Usp34	APN	11	23,467,243 (GRCm38)	missense	possibly damaging	0.91
IGL02423:Usp34	APN	11	23,354,900 (GRCm38)	missense	probably benign	0.11
IGL02491:Usp34	APN	11	23,432,630 (GRCm38)	missense	probably damaging	0.98
IGL02532:Usp34	APN	11	23,370,291 (GRCm38)	missense	probably damaging	0.99
IGL02561:Usp34	APN	11	23,351,652 (GRCm38)	missense	probably benign	0.09
IGL02706:Usp34	APN	11	23,388,659 (GRCm38)	splice site	probably benign
IGL02891:Usp34	APN	11	23,487,166 (GRCm38)	missense	probably benign	0.09
IGL03079:Usp34	APN	11	23,432,247 (GRCm38)	missense	possibly damaging	0.48
IGL03089:Usp34	APN	11	23,446,958 (GRCm38)	missense	possibly damaging	0.84
IGL03175:Usp34	APN	11	23,488,686 (GRCm38)	missense	probably benign
IGL03256:Usp34	APN	11	23,420,090 (GRCm38)	nonsense	probably null
IGL03280:Usp34	APN	11	23,354,897 (GRCm38)	missense	probably damaging	1.00
IGL03289:Usp34	APN	11	23,393,818 (GRCm38)	missense	possibly damaging	0.94
IGL03408:Usp34	APN	11	23,446,957 (GRCm38)	missense	possibly damaging	0.92
Chub	UTSW	11	23,464,686 (GRCm38)	missense	probably damaging	0.99
Cicione	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R5571_Usp34_680	UTSW	11	23,457,975 (GRCm38)	missense	probably damaging	0.99
R5713_Usp34_003	UTSW	11	23,343,515 (GRCm38)	missense	possibly damaging	0.94
Roebuck	UTSW	11	23,486,810 (GRCm38)	splice site	probably benign
stoat	UTSW	11	23,487,203 (GRCm38)	missense
tunnelvision	UTSW	11	23,446,968 (GRCm38)	missense
I2288:Usp34	UTSW	11	23,432,473 (GRCm38)	splice site	probably benign
R0047:Usp34	UTSW	11	23,464,403 (GRCm38)	missense	probably benign	0.34
R0047:Usp34	UTSW	11	23,464,403 (GRCm38)	missense	probably benign	0.34
R0099:Usp34	UTSW	11	23,363,111 (GRCm38)	missense	probably damaging	1.00
R0240:Usp34	UTSW	11	23,433,206 (GRCm38)	missense	probably damaging	0.99
R0240:Usp34	UTSW	11	23,433,206 (GRCm38)	missense	probably damaging	0.99
R0403:Usp34	UTSW	11	23,333,838 (GRCm38)	missense	possibly damaging	0.82
R0446:Usp34	UTSW	11	23,467,207 (GRCm38)	missense	probably damaging	0.97
R0455:Usp34	UTSW	11	23,446,741 (GRCm38)	splice site	probably benign
R0470:Usp34	UTSW	11	23,436,001 (GRCm38)	missense	possibly damaging	0.94
R0472:Usp34	UTSW	11	23,384,509 (GRCm38)	splice site	probably benign
R0512:Usp34	UTSW	11	23,451,997 (GRCm38)	missense	probably benign	0.04
R0557:Usp34	UTSW	11	23,403,848 (GRCm38)	missense	probably damaging	0.98
R0562:Usp34	UTSW	11	23,432,406 (GRCm38)	splice site	probably benign
R0656:Usp34	UTSW	11	23,472,967 (GRCm38)	missense	probably damaging	0.99
R0693:Usp34	UTSW	11	23,452,637 (GRCm38)	missense	probably damaging	0.97
R0739:Usp34	UTSW	11	23,467,243 (GRCm38)	missense	possibly damaging	0.91
R1061:Usp34	UTSW	11	23,384,420 (GRCm38)	missense	possibly damaging	0.51
R1078:Usp34	UTSW	11	23,433,175 (GRCm38)	splice site	probably benign
R1223:Usp34	UTSW	11	23,446,464 (GRCm38)	splice site	probably null
R1295:Usp34	UTSW	11	23,384,477 (GRCm38)	missense	probably damaging	1.00
R1430:Usp34	UTSW	11	23,459,151 (GRCm38)	missense	probably damaging	0.97
R1445:Usp34	UTSW	11	23,351,629 (GRCm38)	missense	probably damaging	0.99
R1468:Usp34	UTSW	11	23,441,171 (GRCm38)	missense	probably damaging	1.00
R1468:Usp34	UTSW	11	23,441,171 (GRCm38)	missense	probably damaging	1.00
R1471:Usp34	UTSW	11	23,488,862 (GRCm38)	missense	probably benign	0.20
R1475:Usp34	UTSW	11	23,473,253 (GRCm38)	missense	probably damaging	0.99
R1628:Usp34	UTSW	11	23,488,725 (GRCm38)	missense	probably damaging	1.00
R1631:Usp34	UTSW	11	23,460,651 (GRCm38)	missense	probably damaging	0.99
R1655:Usp34	UTSW	11	23,375,051 (GRCm38)	missense	probably benign	0.05
R1741:Usp34	UTSW	11	23,364,103 (GRCm38)	missense	probably benign	0.00
R1854:Usp34	UTSW	11	23,426,153 (GRCm38)	missense	probably benign	0.24
R1867:Usp34	UTSW	11	23,361,593 (GRCm38)	missense	possibly damaging	0.82
R1869:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1870:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1871:Usp34	UTSW	11	23,364,479 (GRCm38)	missense	probably benign	0.37
R1967:Usp34	UTSW	11	23,364,503 (GRCm38)	missense	probably benign	0.01
R2051:Usp34	UTSW	11	23,464,468 (GRCm38)	missense	probably damaging	0.97
R2132:Usp34	UTSW	11	23,464,556 (GRCm38)	missense	possibly damaging	0.95
R2156:Usp34	UTSW	11	23,382,602 (GRCm38)	missense	probably damaging	0.98
R2205:Usp34	UTSW	11	23,385,147 (GRCm38)	missense	probably damaging	0.97
R2342:Usp34	UTSW	11	23,403,599 (GRCm38)	missense	possibly damaging	0.46
R3431:Usp34	UTSW	11	23,370,466 (GRCm38)	missense	possibly damaging	0.95
R3812:Usp34	UTSW	11	23,464,517 (GRCm38)	missense	possibly damaging	0.94
R3872:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3873:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3874:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3875:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R3925:Usp34	UTSW	11	23,343,640 (GRCm38)	missense	probably benign	0.28
R3972:Usp34	UTSW	11	23,457,803 (GRCm38)	missense	probably damaging	1.00
R4018:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R4042:Usp34	UTSW	11	23,489,033 (GRCm38)	missense	possibly damaging	0.85
R4155:Usp34	UTSW	11	23,417,676 (GRCm38)	missense	probably damaging	0.99
R4197:Usp34	UTSW	11	23,444,189 (GRCm38)	missense	probably damaging	0.98
R4352:Usp34	UTSW	11	23,320,727 (GRCm38)	missense	possibly damaging	0.73
R4379:Usp34	UTSW	11	23,384,499 (GRCm38)	missense	possibly damaging	0.52
R4444:Usp34	UTSW	11	23,435,998 (GRCm38)	missense	probably damaging	0.98
R4475:Usp34	UTSW	11	23,457,975 (GRCm38)	missense	possibly damaging	0.95
R4501:Usp34	UTSW	11	23,401,529 (GRCm38)	missense	probably damaging	1.00
R4527:Usp34	UTSW	11	23,421,257 (GRCm38)	missense	possibly damaging	0.57
R4603:Usp34	UTSW	11	23,464,633 (GRCm38)	missense	probably damaging	0.97
R4612:Usp34	UTSW	11	23,432,268 (GRCm38)	missense	probably damaging	0.99
R4673:Usp34	UTSW	11	23,364,480 (GRCm38)	small deletion	probably benign
R4707:Usp34	UTSW	11	23,487,215 (GRCm38)	missense	probably damaging	1.00
R4736:Usp34	UTSW	11	23,393,749 (GRCm38)	splice site	probably null
R4867:Usp34	UTSW	11	23,451,999 (GRCm38)	missense	probably benign	0.28
R4879:Usp34	UTSW	11	23,373,410 (GRCm38)	missense	possibly damaging	0.94
R4977:Usp34	UTSW	11	23,488,982 (GRCm38)	missense	probably damaging	1.00
R5004:Usp34	UTSW	11	23,464,586 (GRCm38)	missense	probably damaging	1.00
R5057:Usp34	UTSW	11	23,458,086 (GRCm38)	intron	probably benign
R5068:Usp34	UTSW	11	23,460,665 (GRCm38)	missense	possibly damaging	0.94
R5304:Usp34	UTSW	11	23,343,616 (GRCm38)	missense	probably damaging	1.00
R5320:Usp34	UTSW	11	23,333,739 (GRCm38)	missense	probably benign
R5327:Usp34	UTSW	11	23,468,846 (GRCm38)	missense	probably damaging	1.00
R5328:Usp34	UTSW	11	23,488,659 (GRCm38)	missense	probably benign	0.04
R5328:Usp34	UTSW	11	23,464,616 (GRCm38)	missense	probably benign	0.01
R5390:Usp34	UTSW	11	23,444,202 (GRCm38)	critical splice donor site	probably null
R5434:Usp34	UTSW	11	23,412,271 (GRCm38)	missense	probably damaging	0.99
R5523:Usp34	UTSW	11	23,349,198 (GRCm38)	missense	probably benign	0.39
R5567:Usp34	UTSW	11	23,488,336 (GRCm38)	missense	probably damaging	0.97
R5571:Usp34	UTSW	11	23,457,975 (GRCm38)	missense	probably damaging	0.99
R5645:Usp34	UTSW	11	23,375,024 (GRCm38)	missense	possibly damaging	0.86
R5713:Usp34	UTSW	11	23,343,515 (GRCm38)	missense	possibly damaging	0.94
R5719:Usp34	UTSW	11	23,354,846 (GRCm38)	missense	probably benign	0.00
R5813:Usp34	UTSW	11	23,421,340 (GRCm38)	missense	probably benign	0.38
R5921:Usp34	UTSW	11	23,464,686 (GRCm38)	missense	probably damaging	0.99
R5928:Usp34	UTSW	11	23,436,040 (GRCm38)	missense	probably damaging	0.98
R5944:Usp34	UTSW	11	23,363,089 (GRCm38)	missense	probably damaging	1.00
R6198:Usp34	UTSW	11	23,484,127 (GRCm38)	missense	probably damaging	1.00
R6229:Usp34	UTSW	11	23,446,778 (GRCm38)	missense	probably damaging	0.99
R6306:Usp34	UTSW	11	23,412,260 (GRCm38)	missense	possibly damaging	0.94
R6320:Usp34	UTSW	11	23,452,520 (GRCm38)	missense	probably damaging	0.98
R6341:Usp34	UTSW	11	23,381,353 (GRCm38)	missense	probably damaging	0.97
R6374:Usp34	UTSW	11	23,438,914 (GRCm38)	missense	probably damaging	1.00
R6398:Usp34	UTSW	11	23,488,666 (GRCm38)	missense	probably benign
R6438:Usp34	UTSW	11	23,364,266 (GRCm38)	missense	probably benign	0.02
R6668:Usp34	UTSW	11	23,460,659 (GRCm38)	missense	probably damaging	0.97
R6700:Usp34	UTSW	11	23,439,011 (GRCm38)	missense	probably damaging	1.00
R6783:Usp34	UTSW	11	23,412,318 (GRCm38)	missense	probably damaging	1.00
R6821:Usp34	UTSW	11	23,367,491 (GRCm38)	missense	possibly damaging	0.79
R6855:Usp34	UTSW	11	23,452,569 (GRCm38)	missense	possibly damaging	0.94
R6916:Usp34	UTSW	11	23,458,023 (GRCm38)	missense	probably damaging	0.98
R7020:Usp34	UTSW	11	23,393,954 (GRCm38)	missense	probably benign	0.05
R7026:Usp34	UTSW	11	23,361,622 (GRCm38)	missense	probably damaging	1.00
R7085:Usp34	UTSW	11	23,363,097 (GRCm38)	missense
R7101:Usp34	UTSW	11	23,426,183 (GRCm38)	missense
R7168:Usp34	UTSW	11	23,464,585 (GRCm38)	missense
R7192:Usp34	UTSW	11	23,460,571 (GRCm38)	missense
R7264:Usp34	UTSW	11	23,333,566 (GRCm38)	missense	probably benign	0.00
R7325:Usp34	UTSW	11	23,419,052 (GRCm38)	missense
R7343:Usp34	UTSW	11	23,488,868 (GRCm38)	missense
R7358:Usp34	UTSW	11	23,361,683 (GRCm38)	missense	probably damaging	0.99
R7369:Usp34	UTSW	11	23,432,361 (GRCm38)	missense
R7389:Usp34	UTSW	11	23,345,200 (GRCm38)	missense
R7459:Usp34	UTSW	11	23,364,458 (GRCm38)	missense	possibly damaging	0.53
R7517:Usp34	UTSW	11	23,446,968 (GRCm38)	missense
R7729:Usp34	UTSW	11	23,449,268 (GRCm38)	missense
R7777:Usp34	UTSW	11	23,382,638 (GRCm38)	missense
R7810:Usp34	UTSW	11	23,412,314 (GRCm38)	missense
R7836:Usp34	UTSW	11	23,446,614 (GRCm38)	missense
R7862:Usp34	UTSW	11	23,464,718 (GRCm38)	missense
R7993:Usp34	UTSW	11	23,377,622 (GRCm38)	missense
R8050:Usp34	UTSW	11	23,446,787 (GRCm38)	missense
R8054:Usp34	UTSW	11	23,361,295 (GRCm38)	missense
R8239:Usp34	UTSW	11	23,446,750 (GRCm38)	missense
R8266:Usp34	UTSW	11	23,486,810 (GRCm38)	splice site	probably benign
R8347:Usp34	UTSW	11	23,412,345 (GRCm38)	missense
R8409:Usp34	UTSW	11	23,457,811 (GRCm38)	missense
R8692:Usp34	UTSW	11	23,429,325 (GRCm38)	missense
R8694:Usp34	UTSW	11	23,484,161 (GRCm38)	missense
R8734:Usp34	UTSW	11	23,444,184 (GRCm38)	missense
R8806:Usp34	UTSW	11	23,484,143 (GRCm38)	missense
R8914:Usp34	UTSW	11	23,343,604 (GRCm38)	missense
R8987:Usp34	UTSW	11	23,464,267 (GRCm38)	missense
R9013:Usp34	UTSW	11	23,370,302 (GRCm38)	missense
R9108:Usp34	UTSW	11	23,370,528 (GRCm38)	missense
R9264:Usp34	UTSW	11	23,489,064 (GRCm38)	missense
R9301:Usp34	UTSW	11	23,472,951 (GRCm38)	missense
R9375:Usp34	UTSW	11	23,487,203 (GRCm38)	missense
R9385:Usp34	UTSW	11	23,449,223 (GRCm38)	missense
R9500:Usp34	UTSW	11	23,381,337 (GRCm38)	missense	probably damaging	0.99
R9566:Usp34	UTSW	11	23,367,529 (GRCm38)	missense
R9629:Usp34	UTSW	11	23,364,364 (GRCm38)	missense
R9679:Usp34	UTSW	11	23,444,369 (GRCm38)	missense
R9680:Usp34	UTSW	11	23,367,385 (GRCm38)	missense	possibly damaging	0.94
R9686:Usp34	UTSW	11	23,474,351 (GRCm38)	missense
R9752:Usp34	UTSW	11	23,459,182 (GRCm38)	missense	probably benign	0.11
X0023:Usp34	UTSW	11	23,375,028 (GRCm38)	missense	possibly damaging	0.73
X0057:Usp34	UTSW	11	23,457,824 (GRCm38)	missense	possibly damaging	0.86
Z1176:Usp34	UTSW	11	23,473,221 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGTTGCTTGGGAACAATGATCAGCTAA -3'
(R):5'- AAGAGGACCTCTAGCCTCCATCTATCT -3'

Sequencing Primer
(F):5'- gaactcccagcaccgac -3'
(R):5'- TCTGTACACAAACACTGCTGGG -3'

Posted On

2013-05-23