Incidental Mutation 'R5069:Plxnd1'
| ID |
388536 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnd1
|
| Ensembl Gene |
ENSMUSG00000030123 |
| Gene Name |
plexin D1 |
| Synonyms |
b2b553Clo, 6230425C21Rik, b2b1863Clo |
| MMRRC Submission |
042659-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5069 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
115954811-115995005 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 115965901 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 1274
(V1274E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000015511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000015511]
|
| AlphaFold |
Q3UH93 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000015511
AA Change: V1274E
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000015511
Gene: ENSMUSG00000030123
AA Change: V1274E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
48 |
N/A |
INTRINSIC |
|
Sema
|
61 |
531 |
6.52e-90 |
SMART |
|
PSI
|
550 |
603 |
6.06e-12 |
SMART |
|
PSI
|
703 |
755 |
1.06e-2 |
SMART |
|
Blast:PSI
|
850 |
891 |
9e-20 |
BLAST |
|
IPT
|
892 |
981 |
4.43e-20 |
SMART |
|
IPT
|
982 |
1068 |
6.61e-19 |
SMART |
|
IPT
|
1070 |
1149 |
6.13e-14 |
SMART |
|
transmembrane domain
|
1271 |
1293 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1345 |
1888 |
5e-238 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131590
|
| SMART Domains |
Protein: ENSMUSP00000115650
Gene: ENSMUSG00000030123
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:PSI
|
2 |
34 |
1e-13 |
BLAST |
|
IPT
|
35 |
124 |
4.43e-20 |
SMART |
|
Blast:IPT
|
125 |
177 |
3e-30 |
BLAST |
|
Pfam:TIG
|
180 |
233 |
4.6e-6 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display neonatal lethality, thin-walled atria, and vascular abnormalities including abnormal branchial arch artery development, cardiac outflow tract abnormalities, and reduced vascular smooth muscle around some vessels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,661,792 (GRCm38) |
S739P |
possibly damaging |
Het |
| AAdacl4fm3 |
T |
A |
4: 144,703,867 (GRCm38) |
D184V |
probably damaging |
Het |
| Actn2 |
A |
G |
13: 12,288,522 (GRCm38) |
I464T |
possibly damaging |
Het |
| Adcy7 |
T |
C |
8: 88,327,697 (GRCm38) |
L1060P |
probably damaging |
Het |
| Aff3 |
A |
G |
1: 38,181,613 (GRCm38) |
|
probably null |
Het |
| Ankar |
T |
C |
1: 72,680,210 (GRCm38) |
|
probably null |
Het |
| Ankrd27 |
A |
T |
7: 35,628,435 (GRCm38) |
K793N |
probably damaging |
Het |
| Arhgef28 |
T |
C |
13: 98,075,206 (GRCm38) |
T90A |
probably damaging |
Het |
| Armc9 |
A |
T |
1: 86,257,237 (GRCm38) |
H670L |
probably benign |
Het |
| Arvcf |
A |
G |
16: 18,398,986 (GRCm38) |
Y412C |
probably damaging |
Het |
| Ass1 |
C |
T |
2: 31,510,173 (GRCm38) |
T301M |
probably damaging |
Het |
| Baiap3 |
A |
T |
17: 25,249,108 (GRCm38) |
C283S |
probably damaging |
Het |
| Birc6 |
C |
T |
17: 74,565,972 (GRCm38) |
R409C |
probably damaging |
Het |
| Calcoco1 |
A |
G |
15: 102,711,092 (GRCm38) |
L354P |
probably damaging |
Het |
| Cdh3 |
A |
G |
8: 106,536,826 (GRCm38) |
N126S |
probably benign |
Het |
| Cfap54 |
A |
C |
10: 92,937,774 (GRCm38) |
F135L |
probably benign |
Het |
| Dlg1 |
G |
T |
16: 31,684,295 (GRCm38) |
|
probably null |
Het |
| Dnah3 |
T |
C |
7: 120,032,790 (GRCm38) |
H1314R |
probably benign |
Het |
| Dsp |
A |
C |
13: 38,197,123 (GRCm38) |
T2615P |
possibly damaging |
Het |
| Elapor2 |
T |
A |
5: 9,440,897 (GRCm38) |
C636S |
probably damaging |
Het |
| Enpp2 |
T |
C |
15: 54,864,054 (GRCm38) |
Y513C |
probably damaging |
Het |
| Ercc6 |
T |
C |
14: 32,570,063 (GRCm38) |
V1128A |
probably benign |
Het |
| Firrm |
T |
C |
1: 163,987,674 (GRCm38) |
T93A |
possibly damaging |
Het |
| Gipc2 |
A |
G |
3: 152,094,248 (GRCm38) |
F282L |
probably benign |
Het |
| Gm1043 |
T |
G |
5: 37,187,236 (GRCm38) |
L231R |
probably damaging |
Het |
| Gpr153 |
T |
A |
4: 152,279,883 (GRCm38) |
M132K |
probably damaging |
Het |
| Hbs1l |
T |
A |
10: 21,354,647 (GRCm38) |
S496T |
probably damaging |
Het |
| Inpp5f |
A |
G |
7: 128,676,727 (GRCm38) |
|
probably null |
Het |
| Kat6a |
G |
A |
8: 22,903,133 (GRCm38) |
C209Y |
probably damaging |
Het |
| Kcna2 |
T |
A |
3: 107,104,637 (GRCm38) |
V178D |
probably damaging |
Het |
| Krt75 |
A |
G |
15: 101,566,238 (GRCm38) |
|
probably null |
Het |
| Letm2 |
G |
A |
8: 25,593,964 (GRCm38) |
Q84* |
probably null |
Het |
| Mib1 |
A |
G |
18: 10,793,002 (GRCm38) |
E646G |
probably damaging |
Het |
| Mmp14 |
T |
A |
14: 54,439,113 (GRCm38) |
Y372N |
probably damaging |
Het |
| Muc6 |
A |
G |
7: 141,651,299 (GRCm38) |
C218R |
probably damaging |
Het |
| Myof |
A |
T |
19: 37,905,325 (GRCm38) |
I1130N |
possibly damaging |
Het |
| Neil3 |
A |
G |
8: 53,601,041 (GRCm38) |
S318P |
possibly damaging |
Het |
| Nhlh1 |
A |
G |
1: 172,053,900 (GRCm38) |
V133A |
probably benign |
Het |
| Nup153 |
A |
C |
13: 46,709,792 (GRCm38) |
S331A |
probably benign |
Het |
| Nup98 |
T |
C |
7: 102,145,655 (GRCm38) |
T882A |
probably benign |
Het |
| Or11g2 |
T |
A |
14: 50,618,740 (GRCm38) |
C173S |
probably damaging |
Het |
| Or11h4 |
C |
A |
14: 50,737,074 (GRCm38) |
L29F |
probably benign |
Het |
| Or52ab4 |
A |
T |
7: 103,338,022 (GRCm38) |
|
probably null |
Het |
| Or9s23 |
T |
A |
1: 92,573,413 (GRCm38) |
S81T |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,997,037 (GRCm38) |
A91S |
probably damaging |
Het |
| Pald1 |
A |
T |
10: 61,341,246 (GRCm38) |
M675K |
possibly damaging |
Het |
| Pex5 |
A |
G |
6: 124,413,596 (GRCm38) |
S97P |
probably benign |
Het |
| Pitpnm1 |
C |
T |
19: 4,111,140 (GRCm38) |
A897V |
probably benign |
Het |
| Polr2a |
T |
C |
11: 69,736,735 (GRCm38) |
|
probably null |
Het |
| Ppfia1 |
G |
A |
7: 144,514,473 (GRCm38) |
Q446* |
probably null |
Het |
| Psma2 |
G |
A |
13: 14,616,028 (GRCm38) |
V20I |
probably benign |
Het |
| Pwwp4a |
T |
C |
X: 73,127,971 (GRCm38) |
I323T |
probably damaging |
Het |
| Rhbdl2 |
T |
A |
4: 123,817,917 (GRCm38) |
L149* |
probably null |
Het |
| Rnf17 |
T |
C |
14: 56,505,928 (GRCm38) |
V1317A |
probably damaging |
Het |
| Rtel1 |
G |
A |
2: 181,355,492 (GRCm38) |
V1042M |
probably benign |
Het |
| Sidt2 |
A |
T |
9: 45,939,461 (GRCm38) |
|
probably null |
Het |
| Slc11a1 |
G |
A |
1: 74,385,184 (GRCm38) |
A434T |
probably damaging |
Het |
| Slc28a2b |
A |
T |
2: 122,494,373 (GRCm38) |
N142I |
possibly damaging |
Het |
| Slc4a10 |
G |
A |
2: 62,267,571 (GRCm38) |
R508H |
probably benign |
Het |
| Slc5a8 |
A |
T |
10: 88,886,598 (GRCm38) |
I98F |
possibly damaging |
Het |
| Slf2 |
T |
A |
19: 44,935,253 (GRCm38) |
S169T |
possibly damaging |
Het |
| Snx33 |
A |
T |
9: 56,926,191 (GRCm38) |
I198N |
probably damaging |
Het |
| Spock3 |
A |
G |
8: 63,355,265 (GRCm38) |
T396A |
probably benign |
Het |
| Sva |
A |
T |
6: 42,038,417 (GRCm38) |
|
probably benign |
Het |
| Syt7 |
A |
G |
19: 10,439,237 (GRCm38) |
N261S |
probably benign |
Het |
| Taar7b |
T |
G |
10: 24,000,461 (GRCm38) |
S175A |
probably benign |
Het |
| Thoc2 |
C |
T |
X: 41,806,693 (GRCm38) |
E1491K |
probably damaging |
Het |
| Tlr1 |
T |
C |
5: 64,926,400 (GRCm38) |
Y278C |
probably benign |
Het |
| Tph2 |
T |
A |
10: 115,151,174 (GRCm38) |
Y237F |
probably benign |
Het |
| Trim35 |
C |
T |
14: 66,308,972 (GRCm38) |
|
probably benign |
Het |
| Trpm4 |
T |
G |
7: 45,310,469 (GRCm38) |
Y667S |
probably damaging |
Het |
| Ttc27 |
T |
A |
17: 74,799,342 (GRCm38) |
H541Q |
probably damaging |
Het |
| Ube4a |
T |
C |
9: 44,940,089 (GRCm38) |
H709R |
probably damaging |
Het |
| Vwa7 |
G |
A |
17: 35,024,190 (GRCm38) |
V615I |
probably benign |
Het |
| Wars2 |
A |
G |
3: 99,187,533 (GRCm38) |
H48R |
probably damaging |
Het |
| Xlr4c |
T |
A |
X: 73,238,684 (GRCm38) |
K121M |
probably damaging |
Het |
| Zfc3h1 |
T |
A |
10: 115,418,783 (GRCm38) |
C1427* |
probably null |
Het |
|
| Other mutations in Plxnd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00764:Plxnd1
|
APN |
6 |
115,967,972 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
IGL01099:Plxnd1
|
APN |
6 |
115,969,945 (GRCm38) |
missense |
probably benign |
|
|
IGL01323:Plxnd1
|
APN |
6 |
115,966,799 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL01382:Plxnd1
|
APN |
6 |
115,960,527 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01786:Plxnd1
|
APN |
6 |
115,959,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02244:Plxnd1
|
APN |
6 |
115,978,257 (GRCm38) |
missense |
probably benign |
0.39 |
|
IGL02272:Plxnd1
|
APN |
6 |
115,993,628 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02293:Plxnd1
|
APN |
6 |
115,963,913 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02465:Plxnd1
|
APN |
6 |
115,955,742 (GRCm38) |
makesense |
probably null |
|
|
IGL02873:Plxnd1
|
APN |
6 |
115,959,976 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03209:Plxnd1
|
APN |
6 |
115,962,357 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Hiss
|
UTSW |
6 |
115,969,929 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
murmer
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
mutter
|
UTSW |
6 |
115,968,044 (GRCm38) |
missense |
probably benign |
0.27 |
|
rattle
|
UTSW |
6 |
115,959,794 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0357:Plxnd1
|
UTSW |
6 |
115,969,460 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0646:Plxnd1
|
UTSW |
6 |
115,958,699 (GRCm38) |
splice site |
probably benign |
|
|
R0648:Plxnd1
|
UTSW |
6 |
115,994,001 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R0718:Plxnd1
|
UTSW |
6 |
115,966,638 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R1116:Plxnd1
|
UTSW |
6 |
115,967,005 (GRCm38) |
splice site |
probably null |
|
|
R1292:Plxnd1
|
UTSW |
6 |
115,962,683 (GRCm38) |
unclassified |
probably benign |
|
|
R1715:Plxnd1
|
UTSW |
6 |
115,968,681 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1760:Plxnd1
|
UTSW |
6 |
115,967,779 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1799:Plxnd1
|
UTSW |
6 |
115,994,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1817:Plxnd1
|
UTSW |
6 |
115,980,601 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R1848:Plxnd1
|
UTSW |
6 |
115,966,546 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1851:Plxnd1
|
UTSW |
6 |
115,963,914 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1864:Plxnd1
|
UTSW |
6 |
115,969,441 (GRCm38) |
splice site |
probably null |
|
|
R1865:Plxnd1
|
UTSW |
6 |
115,969,441 (GRCm38) |
splice site |
probably null |
|
|
R1875:Plxnd1
|
UTSW |
6 |
115,978,084 (GRCm38) |
splice site |
probably null |
|
|
R1899:Plxnd1
|
UTSW |
6 |
115,969,363 (GRCm38) |
missense |
probably benign |
|
|
R1913:Plxnd1
|
UTSW |
6 |
115,978,017 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R1970:Plxnd1
|
UTSW |
6 |
115,962,517 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2007:Plxnd1
|
UTSW |
6 |
115,967,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2134:Plxnd1
|
UTSW |
6 |
115,957,548 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2202:Plxnd1
|
UTSW |
6 |
115,962,764 (GRCm38) |
missense |
probably benign |
0.45 |
|
R2230:Plxnd1
|
UTSW |
6 |
115,964,144 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2267:Plxnd1
|
UTSW |
6 |
115,962,743 (GRCm38) |
missense |
probably benign |
0.29 |
|
R2427:Plxnd1
|
UTSW |
6 |
115,967,748 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4108:Plxnd1
|
UTSW |
6 |
115,959,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4233:Plxnd1
|
UTSW |
6 |
115,965,953 (GRCm38) |
missense |
probably benign |
0.30 |
|
R4280:Plxnd1
|
UTSW |
6 |
115,956,095 (GRCm38) |
splice site |
probably null |
|
|
R4280:Plxnd1
|
UTSW |
6 |
115,956,094 (GRCm38) |
splice site |
probably benign |
|
|
R4346:Plxnd1
|
UTSW |
6 |
115,977,980 (GRCm38) |
missense |
probably benign |
0.16 |
|
R4439:Plxnd1
|
UTSW |
6 |
115,993,976 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4572:Plxnd1
|
UTSW |
6 |
115,955,756 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4576:Plxnd1
|
UTSW |
6 |
115,968,044 (GRCm38) |
missense |
probably benign |
0.27 |
|
R4599:Plxnd1
|
UTSW |
6 |
115,994,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4614:Plxnd1
|
UTSW |
6 |
115,972,525 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4700:Plxnd1
|
UTSW |
6 |
115,958,615 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4705:Plxnd1
|
UTSW |
6 |
115,958,620 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4806:Plxnd1
|
UTSW |
6 |
115,960,855 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Plxnd1
|
UTSW |
6 |
115,955,765 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4977:Plxnd1
|
UTSW |
6 |
115,994,376 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5155:Plxnd1
|
UTSW |
6 |
115,958,988 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5460:Plxnd1
|
UTSW |
6 |
115,957,648 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5729:Plxnd1
|
UTSW |
6 |
115,965,877 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5909:Plxnd1
|
UTSW |
6 |
115,968,688 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5992:Plxnd1
|
UTSW |
6 |
115,967,787 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6129:Plxnd1
|
UTSW |
6 |
115,978,174 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6254:Plxnd1
|
UTSW |
6 |
115,977,960 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6273:Plxnd1
|
UTSW |
6 |
115,978,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6310:Plxnd1
|
UTSW |
6 |
115,976,736 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6732:Plxnd1
|
UTSW |
6 |
115,969,929 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6857:Plxnd1
|
UTSW |
6 |
115,993,763 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7243:Plxnd1
|
UTSW |
6 |
115,972,507 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7282:Plxnd1
|
UTSW |
6 |
115,960,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7632:Plxnd1
|
UTSW |
6 |
115,976,639 (GRCm38) |
missense |
probably benign |
|
|
R7699:Plxnd1
|
UTSW |
6 |
115,959,794 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7915:Plxnd1
|
UTSW |
6 |
115,966,918 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8090:Plxnd1
|
UTSW |
6 |
115,956,617 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8382:Plxnd1
|
UTSW |
6 |
115,972,472 (GRCm38) |
missense |
probably benign |
|
|
R8507:Plxnd1
|
UTSW |
6 |
115,966,905 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8539:Plxnd1
|
UTSW |
6 |
115,962,807 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R8548:Plxnd1
|
UTSW |
6 |
115,957,597 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8963:Plxnd1
|
UTSW |
6 |
115,972,545 (GRCm38) |
nonsense |
probably null |
|
|
R9119:Plxnd1
|
UTSW |
6 |
115,955,871 (GRCm38) |
splice site |
probably benign |
|
|
R9177:Plxnd1
|
UTSW |
6 |
115,966,508 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9182:Plxnd1
|
UTSW |
6 |
115,993,785 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9185:Plxnd1
|
UTSW |
6 |
115,957,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9226:Plxnd1
|
UTSW |
6 |
115,957,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9433:Plxnd1
|
UTSW |
6 |
115,968,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9449:Plxnd1
|
UTSW |
6 |
115,955,769 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9451:Plxnd1
|
UTSW |
6 |
115,963,316 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R9599:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9627:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9644:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9672:Plxnd1
|
UTSW |
6 |
115,963,313 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
X0024:Plxnd1
|
UTSW |
6 |
115,963,310 (GRCm38) |
missense |
probably benign |
0.02 |
|
X0026:Plxnd1
|
UTSW |
6 |
115,966,784 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
Z1088:Plxnd1
|
UTSW |
6 |
115,967,510 (GRCm38) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGACAAACTTCTTTAGTAGCTCC -3'
(R):5'- TTGTCTGTGAGGCTCAGAGC -3'
Sequencing Primer
(F):5'- AGTAGCTCCCAAATTCGTCTG -3'
(R):5'- GCTCAGAGCACACAACAGTAAGAAG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation