Incidental Mutation 'R5070:Myo3b'
| ID |
388613 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo3b
|
| Ensembl Gene |
ENSMUSG00000042064 |
| Gene Name |
myosin IIIB |
| Synonyms |
A430065P19Rik |
| MMRRC Submission |
042660-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5070 (G1)
|
| Quality Score |
177 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
69869470-70259542 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 70083456 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 675
(L675P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107862
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000060208]
[ENSMUST00000112243]
|
| AlphaFold |
Q1EG27 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000060208
AA Change: L703P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000055362
Gene: ENSMUSG00000042064
AA Change: L703P
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
43 |
309 |
2.24e-85 |
SMART |
|
MYSc
|
353 |
1075 |
6.61e-260 |
SMART |
|
IQ
|
1075 |
1097 |
9.51e1 |
SMART |
|
IQ
|
1102 |
1124 |
1.73e-5 |
SMART |
|
low complexity region
|
1319 |
1324 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112243
AA Change: L675P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000107862
Gene: ENSMUSG00000042064
AA Change: L675P
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
15 |
281 |
2.24e-85 |
SMART |
|
MYSc
|
325 |
1047 |
6.61e-260 |
SMART |
|
IQ
|
1047 |
1069 |
9.51e1 |
SMART |
|
IQ
|
1074 |
1096 |
1.73e-5 |
SMART |
|
low complexity region
|
1291 |
1296 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.6%
- 20x: 93.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 114 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,383,749 (GRCm39) |
S739P |
possibly damaging |
Het |
| Acacb |
T |
C |
5: 114,384,089 (GRCm39) |
I2206T |
possibly damaging |
Het |
| Actn2 |
A |
G |
13: 12,303,408 (GRCm39) |
I464T |
possibly damaging |
Het |
| AI987944 |
C |
T |
7: 41,024,748 (GRCm39) |
G77D |
probably benign |
Het |
| Ankar |
T |
C |
1: 72,719,369 (GRCm39) |
|
probably null |
Het |
| Armc9 |
A |
T |
1: 86,184,959 (GRCm39) |
H670L |
probably benign |
Het |
| Arvcf |
A |
G |
16: 18,217,736 (GRCm39) |
Y412C |
probably damaging |
Het |
| Baiap3 |
A |
T |
17: 25,468,082 (GRCm39) |
C283S |
probably damaging |
Het |
| Bend3 |
A |
T |
10: 43,369,681 (GRCm39) |
E11D |
probably damaging |
Het |
| Birc6 |
C |
T |
17: 74,872,967 (GRCm39) |
R409C |
probably damaging |
Het |
| Cds2 |
T |
A |
2: 132,144,008 (GRCm39) |
Y4* |
probably null |
Het |
| Celsr1 |
G |
T |
15: 85,823,335 (GRCm39) |
P1691Q |
possibly damaging |
Het |
| Chmp1a |
A |
T |
8: 123,933,054 (GRCm39) |
V133E |
probably benign |
Het |
| Cnbd2 |
T |
C |
2: 156,177,318 (GRCm39) |
V92A |
probably damaging |
Het |
| Comp |
G |
A |
8: 70,829,145 (GRCm39) |
G272S |
probably benign |
Het |
| Csnk1a1 |
T |
A |
18: 61,688,852 (GRCm39) |
F11I |
probably benign |
Het |
| Ctse |
A |
G |
1: 131,595,917 (GRCm39) |
D203G |
probably damaging |
Het |
| Cyp1b1 |
T |
A |
17: 80,018,040 (GRCm39) |
M372L |
probably benign |
Het |
| Cyp2c66 |
T |
A |
19: 39,151,914 (GRCm39) |
S210T |
probably benign |
Het |
| Dnah1 |
G |
A |
14: 31,004,375 (GRCm39) |
P2385S |
probably benign |
Het |
| Dsp |
A |
C |
13: 38,381,099 (GRCm39) |
T2615P |
possibly damaging |
Het |
| Eif4g3 |
A |
G |
4: 137,873,610 (GRCm39) |
T682A |
probably benign |
Het |
| Enpp2 |
T |
C |
15: 54,727,450 (GRCm39) |
Y513C |
probably damaging |
Het |
| Ercc6 |
T |
C |
14: 32,292,020 (GRCm39) |
V1128A |
probably benign |
Het |
| Fam136b-ps |
C |
T |
15: 31,276,862 (GRCm39) |
|
probably benign |
Het |
| Fbxl7 |
T |
A |
15: 26,789,640 (GRCm39) |
H29L |
probably benign |
Het |
| Fbxw22 |
A |
G |
9: 109,214,183 (GRCm39) |
V211A |
probably benign |
Het |
| Frk |
A |
T |
10: 34,360,280 (GRCm39) |
K94* |
probably null |
Het |
| G0s2 |
T |
A |
1: 192,954,870 (GRCm39) |
E71D |
probably damaging |
Het |
| Gfpt1 |
A |
G |
6: 87,030,727 (GRCm39) |
|
probably null |
Het |
| Gga1 |
A |
G |
15: 78,776,217 (GRCm39) |
D420G |
possibly damaging |
Het |
| Gldc |
T |
C |
19: 30,095,998 (GRCm39) |
Q671R |
possibly damaging |
Het |
| Gpc6 |
A |
G |
14: 117,424,181 (GRCm39) |
T90A |
probably benign |
Het |
| Gucy2g |
C |
A |
19: 55,218,219 (GRCm39) |
V410F |
probably damaging |
Het |
| Ifnlr1 |
T |
C |
4: 135,431,509 (GRCm39) |
S233P |
probably benign |
Het |
| Ighv1-9 |
A |
T |
12: 114,547,377 (GRCm39) |
W55R |
probably damaging |
Het |
| Igsf10 |
T |
A |
3: 59,235,714 (GRCm39) |
H1489L |
probably benign |
Het |
| Il17re |
T |
C |
6: 113,435,971 (GRCm39) |
L39P |
probably damaging |
Het |
| Irag1 |
A |
G |
7: 110,524,519 (GRCm39) |
S208P |
probably benign |
Het |
| Kcna2 |
T |
A |
3: 107,011,953 (GRCm39) |
V178D |
probably damaging |
Het |
| Kcnk3 |
A |
G |
5: 30,779,730 (GRCm39) |
H260R |
possibly damaging |
Het |
| Kctd19 |
T |
C |
8: 106,118,631 (GRCm39) |
Y287C |
probably damaging |
Het |
| Klhl28 |
A |
T |
12: 65,004,486 (GRCm39) |
M9K |
probably benign |
Het |
| Lama2 |
A |
G |
10: 27,226,247 (GRCm39) |
|
probably null |
Het |
| Lrrc27 |
A |
T |
7: 138,794,715 (GRCm39) |
D26V |
probably damaging |
Het |
| Mcm4 |
A |
G |
16: 15,443,434 (GRCm39) |
S830P |
probably damaging |
Het |
| Mei1 |
T |
A |
15: 81,961,804 (GRCm39) |
C188S |
possibly damaging |
Het |
| Mettl13 |
C |
T |
1: 162,373,468 (GRCm39) |
R261H |
possibly damaging |
Het |
| Mex3a |
A |
T |
3: 88,443,694 (GRCm39) |
I257F |
probably damaging |
Het |
| Mib1 |
A |
G |
18: 10,793,002 (GRCm39) |
E646G |
probably damaging |
Het |
| Mier2 |
T |
C |
10: 79,385,411 (GRCm39) |
D139G |
probably benign |
Het |
| Mmp14 |
T |
A |
14: 54,676,570 (GRCm39) |
Y372N |
probably damaging |
Het |
| Myh14 |
A |
G |
7: 44,265,672 (GRCm39) |
V1569A |
possibly damaging |
Het |
| Myo18b |
T |
C |
5: 112,909,212 (GRCm39) |
E1977G |
probably damaging |
Het |
| N4bp1 |
A |
G |
8: 87,587,165 (GRCm39) |
V591A |
probably damaging |
Het |
| Nedd9 |
C |
A |
13: 41,470,074 (GRCm39) |
V360L |
probably benign |
Het |
| Oit3 |
C |
T |
10: 59,259,849 (GRCm39) |
R518H |
probably damaging |
Het |
| Or10ag57 |
T |
G |
2: 87,218,507 (GRCm39) |
C153G |
probably damaging |
Het |
| Or11g2 |
A |
G |
14: 50,855,931 (GRCm39) |
N84S |
probably benign |
Het |
| Or11g2 |
T |
A |
14: 50,856,197 (GRCm39) |
C173S |
probably damaging |
Het |
| Or11h4 |
C |
A |
14: 50,974,531 (GRCm39) |
L29F |
probably benign |
Het |
| Or1j14 |
T |
A |
2: 36,417,778 (GRCm39) |
M118K |
probably damaging |
Het |
| Or2aj6 |
A |
G |
16: 19,443,742 (GRCm39) |
I36T |
possibly damaging |
Het |
| Or2j6 |
A |
G |
7: 139,980,482 (GRCm39) |
V159A |
probably benign |
Het |
| Or9s23 |
T |
A |
1: 92,501,135 (GRCm39) |
S81T |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Pask |
A |
T |
1: 93,258,596 (GRCm39) |
C251S |
probably damaging |
Het |
| Pdzk1 |
A |
T |
3: 96,757,637 (GRCm39) |
D31V |
probably benign |
Het |
| Pmfbp1 |
A |
T |
8: 110,256,787 (GRCm39) |
Q497L |
probably damaging |
Het |
| Pofut1 |
T |
C |
2: 153,103,486 (GRCm39) |
|
probably benign |
Het |
| Polr2h |
A |
G |
16: 20,540,716 (GRCm39) |
N95S |
probably damaging |
Het |
| Pou2f3 |
A |
G |
9: 43,056,578 (GRCm39) |
V93A |
possibly damaging |
Het |
| Ppfia1 |
G |
A |
7: 144,068,210 (GRCm39) |
Q446* |
probably null |
Het |
| Prkd1 |
A |
T |
12: 50,441,405 (GRCm39) |
L327* |
probably null |
Het |
| Prrt4 |
T |
C |
6: 29,177,511 (GRCm39) |
E86G |
probably benign |
Het |
| Psen2 |
T |
C |
1: 180,056,422 (GRCm39) |
I393V |
probably benign |
Het |
| Psma2 |
G |
A |
13: 14,790,613 (GRCm39) |
V20I |
probably benign |
Het |
| Qser1 |
C |
T |
2: 104,617,627 (GRCm39) |
V1062I |
possibly damaging |
Het |
| Rab11b |
G |
T |
17: 33,967,855 (GRCm39) |
A114D |
probably damaging |
Het |
| Rag1 |
A |
T |
2: 101,472,656 (GRCm39) |
W829R |
probably damaging |
Het |
| Rgl3 |
A |
G |
9: 21,899,340 (GRCm39) |
|
probably null |
Het |
| Rgs8 |
C |
T |
1: 153,541,650 (GRCm39) |
T3I |
probably damaging |
Het |
| Rnf17 |
T |
C |
14: 56,743,385 (GRCm39) |
V1317A |
probably damaging |
Het |
| Rps6kb2 |
A |
T |
19: 4,213,227 (GRCm39) |
D6E |
probably damaging |
Het |
| Shisal1 |
G |
T |
15: 84,304,364 (GRCm39) |
A14E |
possibly damaging |
Het |
| Skint5 |
T |
A |
4: 113,652,735 (GRCm39) |
I630F |
unknown |
Het |
| Skint7 |
T |
C |
4: 111,841,331 (GRCm39) |
L257P |
probably damaging |
Het |
| Slc11a1 |
G |
A |
1: 74,424,343 (GRCm39) |
A434T |
probably damaging |
Het |
| Slc5a8 |
A |
T |
10: 88,722,460 (GRCm39) |
I98F |
possibly damaging |
Het |
| Sorl1 |
T |
C |
9: 41,943,114 (GRCm39) |
K921E |
possibly damaging |
Het |
| Stub1 |
A |
G |
17: 26,051,112 (GRCm39) |
L90P |
probably damaging |
Het |
| Sycp1 |
A |
T |
3: 102,827,881 (GRCm39) |
S289T |
probably damaging |
Het |
| Taar7b |
T |
G |
10: 23,876,359 (GRCm39) |
S175A |
probably benign |
Het |
| Tead3 |
T |
C |
17: 28,560,451 (GRCm39) |
K51R |
probably benign |
Het |
| Tmed11 |
T |
A |
5: 108,943,089 (GRCm39) |
I30L |
probably benign |
Het |
| Tmem131 |
A |
G |
1: 36,893,986 (GRCm39) |
I139T |
probably damaging |
Het |
| Tmem191 |
A |
G |
16: 17,095,559 (GRCm39) |
Q206R |
probably null |
Het |
| Tph2 |
T |
A |
10: 114,987,079 (GRCm39) |
Y237F |
probably benign |
Het |
| Trim35 |
C |
T |
14: 66,546,421 (GRCm39) |
|
probably benign |
Het |
| Tsc22d1 |
T |
C |
14: 76,655,750 (GRCm39) |
I661T |
probably benign |
Het |
| Ttc27 |
T |
A |
17: 75,106,337 (GRCm39) |
H541Q |
probably damaging |
Het |
| Uqcrq |
A |
G |
11: 53,320,954 (GRCm39) |
|
probably null |
Het |
| Vmn1r215 |
T |
A |
13: 23,260,666 (GRCm39) |
S235R |
probably benign |
Het |
| Vmn1r70 |
T |
C |
7: 10,368,325 (GRCm39) |
V271A |
probably benign |
Het |
| Vps13a |
G |
A |
19: 16,631,848 (GRCm39) |
R2596C |
probably benign |
Het |
| Vwa7 |
G |
A |
17: 35,243,166 (GRCm39) |
V615I |
probably benign |
Het |
| Wdr90 |
T |
C |
17: 26,065,307 (GRCm39) |
T1650A |
probably damaging |
Het |
| Zbtb32 |
T |
A |
7: 30,290,891 (GRCm39) |
M135L |
probably benign |
Het |
| Zc2hc1c |
A |
G |
12: 85,337,288 (GRCm39) |
D315G |
probably benign |
Het |
| Zfc3h1 |
T |
A |
10: 115,254,688 (GRCm39) |
C1427* |
probably null |
Het |
| Zfp30 |
A |
G |
7: 29,485,691 (GRCm39) |
|
probably benign |
Het |
| Zfp428 |
T |
A |
7: 24,214,550 (GRCm39) |
D55E |
probably damaging |
Het |
| Zfyve26 |
A |
T |
12: 79,302,135 (GRCm39) |
N1820K |
probably damaging |
Het |
| Zw10 |
C |
A |
9: 48,988,759 (GRCm39) |
S675* |
probably null |
Het |
|
| Other mutations in Myo3b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00736:Myo3b
|
APN |
2 |
69,935,989 (GRCm39) |
splice site |
probably benign |
|
|
IGL00959:Myo3b
|
APN |
2 |
70,144,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01069:Myo3b
|
APN |
2 |
70,075,735 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01116:Myo3b
|
APN |
2 |
70,119,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02097:Myo3b
|
APN |
2 |
70,069,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02220:Myo3b
|
APN |
2 |
70,119,923 (GRCm39) |
splice site |
probably benign |
|
|
IGL02553:Myo3b
|
APN |
2 |
69,925,568 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02557:Myo3b
|
APN |
2 |
70,085,663 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL02648:Myo3b
|
APN |
2 |
69,935,716 (GRCm39) |
splice site |
probably benign |
|
|
IGL02902:Myo3b
|
APN |
2 |
70,119,745 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL02981:Myo3b
|
APN |
2 |
69,938,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03030:Myo3b
|
APN |
2 |
70,257,160 (GRCm39) |
splice site |
probably benign |
|
|
IGL03031:Myo3b
|
APN |
2 |
70,085,721 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL03068:Myo3b
|
APN |
2 |
70,257,160 (GRCm39) |
splice site |
probably benign |
|
|
IGL03078:Myo3b
|
APN |
2 |
70,117,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03224:Myo3b
|
APN |
2 |
70,180,283 (GRCm39) |
missense |
probably benign |
|
|
IGL03329:Myo3b
|
APN |
2 |
70,084,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0079:Myo3b
|
UTSW |
2 |
69,925,502 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R0226:Myo3b
|
UTSW |
2 |
70,047,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Myo3b
|
UTSW |
2 |
69,935,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Myo3b
|
UTSW |
2 |
69,935,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Myo3b
|
UTSW |
2 |
69,935,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Myo3b
|
UTSW |
2 |
69,935,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0313:Myo3b
|
UTSW |
2 |
70,179,303 (GRCm39) |
nonsense |
probably null |
|
|
R0331:Myo3b
|
UTSW |
2 |
69,925,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0371:Myo3b
|
UTSW |
2 |
70,083,304 (GRCm39) |
splice site |
probably benign |
|
|
R0442:Myo3b
|
UTSW |
2 |
70,069,305 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0964:Myo3b
|
UTSW |
2 |
70,257,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1217:Myo3b
|
UTSW |
2 |
70,161,224 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1429:Myo3b
|
UTSW |
2 |
70,083,351 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1460:Myo3b
|
UTSW |
2 |
70,062,798 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1617:Myo3b
|
UTSW |
2 |
70,111,562 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1628:Myo3b
|
UTSW |
2 |
70,117,306 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1708:Myo3b
|
UTSW |
2 |
70,075,729 (GRCm39) |
nonsense |
probably null |
|
|
R1940:Myo3b
|
UTSW |
2 |
70,088,419 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2407:Myo3b
|
UTSW |
2 |
70,085,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Myo3b
|
UTSW |
2 |
70,086,927 (GRCm39) |
splice site |
probably benign |
|
|
R3687:Myo3b
|
UTSW |
2 |
70,075,658 (GRCm39) |
missense |
probably benign |
|
|
R3745:Myo3b
|
UTSW |
2 |
70,064,829 (GRCm39) |
splice site |
probably benign |
|
|
R4011:Myo3b
|
UTSW |
2 |
69,926,720 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4074:Myo3b
|
UTSW |
2 |
70,119,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4419:Myo3b
|
UTSW |
2 |
69,926,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4496:Myo3b
|
UTSW |
2 |
70,084,748 (GRCm39) |
missense |
probably benign |
|
|
R4539:Myo3b
|
UTSW |
2 |
69,869,491 (GRCm39) |
start codon destroyed |
probably null |
0.00 |
|
R4643:Myo3b
|
UTSW |
2 |
70,069,186 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4657:Myo3b
|
UTSW |
2 |
70,069,243 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4807:Myo3b
|
UTSW |
2 |
69,936,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Myo3b
|
UTSW |
2 |
70,075,253 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4997:Myo3b
|
UTSW |
2 |
70,088,427 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5008:Myo3b
|
UTSW |
2 |
70,088,412 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5072:Myo3b
|
UTSW |
2 |
69,925,593 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5082:Myo3b
|
UTSW |
2 |
70,088,374 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5103:Myo3b
|
UTSW |
2 |
69,926,747 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5109:Myo3b
|
UTSW |
2 |
69,925,637 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5304:Myo3b
|
UTSW |
2 |
70,257,232 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5396:Myo3b
|
UTSW |
2 |
69,957,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5400:Myo3b
|
UTSW |
2 |
69,935,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5468:Myo3b
|
UTSW |
2 |
70,064,785 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5620:Myo3b
|
UTSW |
2 |
70,069,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5646:Myo3b
|
UTSW |
2 |
70,144,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5729:Myo3b
|
UTSW |
2 |
69,936,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5943:Myo3b
|
UTSW |
2 |
70,117,285 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5971:Myo3b
|
UTSW |
2 |
70,069,243 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6091:Myo3b
|
UTSW |
2 |
70,069,113 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6138:Myo3b
|
UTSW |
2 |
70,069,243 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6164:Myo3b
|
UTSW |
2 |
70,075,754 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6177:Myo3b
|
UTSW |
2 |
70,143,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6421:Myo3b
|
UTSW |
2 |
70,143,700 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6478:Myo3b
|
UTSW |
2 |
70,179,304 (GRCm39) |
missense |
probably benign |
|
|
R6606:Myo3b
|
UTSW |
2 |
70,062,829 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6752:Myo3b
|
UTSW |
2 |
70,119,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6982:Myo3b
|
UTSW |
2 |
70,256,409 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6997:Myo3b
|
UTSW |
2 |
69,957,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7032:Myo3b
|
UTSW |
2 |
69,925,608 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7038:Myo3b
|
UTSW |
2 |
69,925,552 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7062:Myo3b
|
UTSW |
2 |
70,047,501 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7537:Myo3b
|
UTSW |
2 |
70,047,513 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7861:Myo3b
|
UTSW |
2 |
69,939,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7955:Myo3b
|
UTSW |
2 |
69,925,623 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7977:Myo3b
|
UTSW |
2 |
70,161,277 (GRCm39) |
missense |
probably benign |
|
|
R7978:Myo3b
|
UTSW |
2 |
70,083,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7987:Myo3b
|
UTSW |
2 |
70,161,277 (GRCm39) |
missense |
probably benign |
|
|
R8803:Myo3b
|
UTSW |
2 |
70,083,338 (GRCm39) |
missense |
probably benign |
|
|
R8843:Myo3b
|
UTSW |
2 |
70,088,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Myo3b
|
UTSW |
2 |
70,069,160 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8904:Myo3b
|
UTSW |
2 |
70,257,252 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8909:Myo3b
|
UTSW |
2 |
70,083,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9031:Myo3b
|
UTSW |
2 |
70,082,094 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9052:Myo3b
|
UTSW |
2 |
70,062,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9251:Myo3b
|
UTSW |
2 |
70,088,425 (GRCm39) |
nonsense |
probably null |
|
|
R9268:Myo3b
|
UTSW |
2 |
70,257,305 (GRCm39) |
makesense |
probably null |
|
|
R9334:Myo3b
|
UTSW |
2 |
70,047,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9377:Myo3b
|
UTSW |
2 |
70,069,242 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9457:Myo3b
|
UTSW |
2 |
69,925,553 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9520:Myo3b
|
UTSW |
2 |
70,062,753 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9593:Myo3b
|
UTSW |
2 |
70,075,648 (GRCm39) |
missense |
probably benign |
0.43 |
|
R9671:Myo3b
|
UTSW |
2 |
70,086,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9790:Myo3b
|
UTSW |
2 |
70,180,287 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9791:Myo3b
|
UTSW |
2 |
70,180,287 (GRCm39) |
missense |
probably benign |
0.35 |
|
U15987:Myo3b
|
UTSW |
2 |
70,069,243 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0025:Myo3b
|
UTSW |
2 |
70,062,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0065:Myo3b
|
UTSW |
2 |
70,088,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Myo3b
|
UTSW |
2 |
70,088,371 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Myo3b
|
UTSW |
2 |
69,926,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGTAGCCACATGTCTAGGAC -3'
(R):5'- CACTGATGCTCTAAACGATGAAAG -3'
Sequencing Primer
(F):5'- GGTAGCCACATGTCTAGGACCATAC -3'
(R):5'- TTTGCCTAAAGAAAAACCACGTAGG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation