Incidental Mutation 'R5072:Ly75'
| ID |
388841 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| Accession Numbers |
Genbank: NM_013825
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5072 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
60292103-60383303 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 60375963 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 121
(Y121H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108152
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000028362
AA Change: Y121H
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: Y121H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112533
AA Change: Y121H
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: Y121H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151984
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 95.9%
- 20x: 90.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930486L24Rik |
A |
T |
13: 60,853,600 (GRCm38) |
H104Q |
probably benign |
Het |
| 4933405L10Rik |
A |
G |
8: 105,709,569 (GRCm38) |
T158A |
possibly damaging |
Het |
| A1cf |
T |
C |
19: 31,917,985 (GRCm38) |
M156T |
probably benign |
Het |
| Abca15 |
A |
G |
7: 120,406,975 (GRCm38) |
Y1620C |
probably damaging |
Het |
| Abca3 |
C |
T |
17: 24,374,300 (GRCm38) |
R224C |
probably damaging |
Het |
| Ablim1 |
A |
G |
19: 57,073,853 (GRCm38) |
|
probably null |
Het |
| Acox2 |
A |
T |
14: 8,241,374 (GRCm38) |
Y579* |
probably null |
Het |
| Adnp |
A |
T |
2: 168,183,001 (GRCm38) |
S791R |
probably damaging |
Het |
| Agbl1 |
A |
G |
7: 76,421,917 (GRCm38) |
E329G |
probably damaging |
Het |
| Alx3 |
G |
T |
3: 107,604,793 (GRCm38) |
S249I |
possibly damaging |
Het |
| Apob |
A |
G |
12: 8,008,714 (GRCm38) |
T2366A |
probably benign |
Het |
| Apool |
C |
T |
X: 112,349,843 (GRCm38) |
Q60* |
probably null |
Het |
| Arid4a |
T |
C |
12: 71,045,079 (GRCm38) |
V213A |
probably benign |
Het |
| Atp7a |
A |
G |
X: 106,109,768 (GRCm38) |
D1092G |
probably benign |
Het |
| Bpifa5 |
A |
T |
2: 154,165,972 (GRCm38) |
E178V |
probably damaging |
Het |
| Car4 |
G |
A |
11: 84,963,367 (GRCm38) |
E47K |
probably benign |
Het |
| Catsper1 |
T |
C |
19: 5,340,046 (GRCm38) |
|
probably null |
Het |
| Ccdc63 |
T |
A |
5: 122,121,055 (GRCm38) |
Q260L |
probably benign |
Het |
| Ccdc83 |
A |
T |
7: 90,250,529 (GRCm38) |
F45Y |
probably damaging |
Het |
| Cct8l1 |
G |
A |
5: 25,516,883 (GRCm38) |
V199I |
probably benign |
Het |
| Cdc23 |
C |
A |
18: 34,651,689 (GRCm38) |
V7L |
unknown |
Het |
| Ces5a |
C |
T |
8: 93,534,668 (GRCm38) |
V44M |
probably damaging |
Het |
| Cltc |
A |
G |
11: 86,717,968 (GRCm38) |
I741T |
possibly damaging |
Het |
| Cnst |
C |
A |
1: 179,622,886 (GRCm38) |
D638E |
possibly damaging |
Het |
| Col13a1 |
A |
G |
10: 61,874,018 (GRCm38) |
|
silent |
Het |
| Cyp2a22 |
A |
T |
7: 26,932,481 (GRCm38) |
F450Y |
probably benign |
Het |
| Cyp2d10 |
C |
T |
15: 82,403,753 (GRCm38) |
R383H |
probably benign |
Het |
| Cyp4a29 |
A |
G |
4: 115,247,663 (GRCm38) |
T123A |
probably benign |
Het |
| Ddx20 |
A |
G |
3: 105,682,875 (GRCm38) |
|
probably null |
Het |
| Dnaja3 |
A |
T |
16: 4,696,425 (GRCm38) |
T274S |
probably damaging |
Het |
| Dot1l |
A |
G |
10: 80,784,646 (GRCm38) |
D514G |
possibly damaging |
Het |
| Dysf |
A |
T |
6: 84,137,272 (GRCm38) |
K1226M |
probably damaging |
Het |
| Epha4 |
T |
C |
1: 77,445,002 (GRCm38) |
Y281C |
probably damaging |
Het |
| Fbxo42 |
T |
C |
4: 141,198,945 (GRCm38) |
W313R |
probably damaging |
Het |
| Fign |
A |
T |
2: 63,979,693 (GRCm38) |
L411* |
probably null |
Het |
| Flt1 |
C |
A |
5: 147,683,939 (GRCm38) |
A132S |
probably benign |
Het |
| Fryl |
G |
A |
5: 73,074,767 (GRCm38) |
P1550L |
probably damaging |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,430,958 (GRCm38) |
|
probably benign |
Het |
| Gprasp2 |
C |
T |
X: 135,842,597 (GRCm38) |
T235I |
possibly damaging |
Het |
| Gtf2ird1 |
G |
T |
5: 134,390,933 (GRCm38) |
|
probably null |
Het |
| H2afb3 |
T |
C |
X: 120,312,846 (GRCm38) |
T84A |
probably damaging |
Het |
| Hal |
A |
T |
10: 93,514,042 (GRCm38) |
I555F |
probably damaging |
Het |
| Hdac6 |
A |
G |
X: 7,944,797 (GRCm38) |
F104L |
probably damaging |
Homo |
| Hist2h2ac |
C |
T |
3: 96,220,783 (GRCm38) |
|
probably benign |
Het |
| Hspg2 |
T |
C |
4: 137,540,230 (GRCm38) |
S2050P |
probably damaging |
Het |
| Irgc1 |
T |
C |
7: 24,432,771 (GRCm38) |
D207G |
probably benign |
Het |
| Kif19a |
G |
A |
11: 114,767,227 (GRCm38) |
M37I |
probably benign |
Het |
| Kiss1r |
C |
A |
10: 79,918,762 (GRCm38) |
S30* |
probably null |
Het |
| Krtap1-4 |
C |
G |
11: 99,583,616 (GRCm38) |
|
probably benign |
Het |
| Lrrfip2 |
A |
G |
9: 111,199,804 (GRCm38) |
E365G |
probably damaging |
Het |
| Man2a1 |
G |
A |
17: 64,659,079 (GRCm38) |
|
probably null |
Het |
| Mkl1 |
A |
G |
15: 81,022,426 (GRCm38) |
V91A |
probably damaging |
Het |
| Mllt10 |
C |
A |
2: 18,109,874 (GRCm38) |
H52N |
possibly damaging |
Het |
| Myo1a |
T |
C |
10: 127,707,419 (GRCm38) |
|
probably null |
Het |
| Myo3b |
C |
A |
2: 70,095,249 (GRCm38) |
T20K |
possibly damaging |
Het |
| Nipsnap2 |
A |
T |
5: 129,739,580 (GRCm38) |
K62N |
probably damaging |
Het |
| Nr1i3 |
C |
T |
1: 171,216,813 (GRCm38) |
T169I |
probably benign |
Het |
| Numbl |
G |
A |
7: 27,280,990 (GRCm38) |
D466N |
probably damaging |
Het |
| Olfr1100 |
A |
T |
2: 86,978,322 (GRCm38) |
V158D |
possibly damaging |
Het |
| Olfr310 |
A |
G |
7: 86,269,591 (GRCm38) |
I66T |
probably damaging |
Het |
| Olfr420 |
A |
T |
1: 174,158,961 (GRCm38) |
I63F |
probably damaging |
Het |
| Olfr639 |
T |
A |
7: 104,012,118 (GRCm38) |
R195W |
probably damaging |
Het |
| Oprm1 |
A |
G |
10: 6,832,550 (GRCm38) |
S398G |
probably benign |
Het |
| Pebp1 |
G |
T |
5: 117,283,410 (GRCm38) |
D156E |
probably benign |
Het |
| Pik3c2g |
T |
A |
6: 139,720,147 (GRCm38) |
C65S |
probably null |
Het |
| Pilra |
A |
G |
5: 137,835,412 (GRCm38) |
F131L |
probably damaging |
Het |
| Pitrm1 |
T |
C |
13: 6,553,190 (GRCm38) |
F91S |
probably damaging |
Het |
| Ppl |
A |
T |
16: 5,088,878 (GRCm38) |
S1184R |
probably benign |
Het |
| Prmt2 |
C |
T |
10: 76,222,556 (GRCm38) |
V140I |
probably damaging |
Het |
| Psg29 |
T |
A |
7: 17,211,838 (GRCm38) |
D444E |
probably damaging |
Het |
| Ptgs1 |
A |
T |
2: 36,251,260 (GRCm38) |
N573I |
probably damaging |
Het |
| Pygb |
C |
T |
2: 150,801,578 (GRCm38) |
T95M |
probably damaging |
Het |
| Rassf9 |
A |
G |
10: 102,545,905 (GRCm38) |
K383E |
probably damaging |
Het |
| Rfk |
T |
A |
19: 17,398,599 (GRCm38) |
F86I |
possibly damaging |
Het |
| Rims2 |
T |
C |
15: 39,462,590 (GRCm38) |
F773L |
probably benign |
Het |
| Sdcbp |
A |
G |
4: 6,393,019 (GRCm38) |
I218V |
probably benign |
Het |
| Slc4a2 |
G |
A |
5: 24,438,762 (GRCm38) |
S855N |
probably benign |
Het |
| Slc8a2 |
T |
C |
7: 16,150,583 (GRCm38) |
L626P |
possibly damaging |
Het |
| Snrpd3 |
G |
T |
10: 75,519,393 (GRCm38) |
C20F |
possibly damaging |
Het |
| Spen |
A |
T |
4: 141,522,302 (GRCm38) |
S58R |
unknown |
Het |
| St3gal2 |
T |
C |
8: 110,957,718 (GRCm38) |
C3R |
possibly damaging |
Het |
| Stab2 |
A |
T |
10: 86,863,558 (GRCm38) |
I481N |
probably benign |
Het |
| Stat5b |
T |
C |
11: 100,808,535 (GRCm38) |
|
probably null |
Het |
| Tmco3 |
G |
T |
8: 13,292,860 (GRCm38) |
E199* |
probably null |
Het |
| Tmem26 |
A |
G |
10: 68,775,348 (GRCm38) |
T216A |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,772,365 (GRCm38) |
|
probably null |
Het |
| Ttn |
C |
T |
2: 76,746,402 (GRCm38) |
V24716I |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,720,478 (GRCm38) |
|
probably null |
Het |
| Uba5 |
T |
C |
9: 104,054,427 (GRCm38) |
E202G |
probably damaging |
Het |
| Ufl1 |
A |
G |
4: 25,254,780 (GRCm38) |
Y559H |
probably benign |
Het |
| Utrn |
A |
T |
10: 12,384,204 (GRCm38) |
|
probably null |
Het |
| Vmn2r111 |
C |
A |
17: 22,548,041 (GRCm38) |
C825F |
probably damaging |
Het |
| Vmn2r113 |
T |
A |
17: 22,958,355 (GRCm38) |
C704* |
probably null |
Het |
| Vmn2r56 |
A |
G |
7: 12,694,056 (GRCm38) |
I761T |
probably benign |
Het |
| Vmn2r98 |
C |
T |
17: 19,066,044 (GRCm38) |
T268I |
probably benign |
Het |
| Zfp263 |
A |
G |
16: 3,746,840 (GRCm38) |
R240G |
possibly damaging |
Het |
| Zfp473 |
T |
A |
7: 44,732,519 (GRCm38) |
I797F |
probably damaging |
Het |
| Zfp68 |
A |
T |
5: 138,606,317 (GRCm38) |
D543E |
probably benign |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,376,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,354,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,321,692 (GRCm38) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,376,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,301,015 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,338,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,299,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,311,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,352,356 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,354,452 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,358,507 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,293,781 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,383,182 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,321,900 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,308,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,376,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,352,070 (GRCm38) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,352,352 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,339,457 (GRCm38) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,318,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,306,404 (GRCm38) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,308,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,316,221 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,293,758 (GRCm38) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,368,757 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,327,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,314,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,311,777 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,349,913 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,334,554 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,352,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,354,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,330,773 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,308,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,352,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,375,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,334,487 (GRCm38) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,365,111 (GRCm38) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,365,145 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,352,381 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,299,082 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,318,439 (GRCm38) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,383,146 (GRCm38) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,375,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,368,873 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,318,376 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,308,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,306,405 (GRCm38) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,306,434 (GRCm38) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,376,184 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,323,852 (GRCm38) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,329,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,334,515 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,334,474 (GRCm38) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,334,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,293,827 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,365,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,332,934 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,314,228 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,318,385 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,334,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,323,926 (GRCm38) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,348,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,331,089 (GRCm38) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,358,559 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,316,098 (GRCm38) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,330,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,327,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,338,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,323,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,306,328 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,354,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,352,133 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,350,004 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAAGCTGTGCTGGGTATGGC -3'
(R):5'- ATCGTCCATGAAAACACTGGC -3'
Sequencing Primer
(F):5'- GCTGGGTATGGCATTTAAATGAAAC -3'
(R):5'- ACTGGCAAGTGCATCCAG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation