Mutagenetix > Incidental Mutation

Incidental Mutation 'R5033:Pcnt'

389380

Institutional Source

Beutler Lab

Gene Symbol

Pcnt

Ensembl Gene

ENSMUSG00000001151

Gene Name

pericentrin (kendrin)

Synonyms

m239Asp, m275Asp, Pcnt2

MMRRC Submission

042624-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5033 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

76351263-76442786 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 76399945 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Serine at position 1401 (C1401S)

Ref Sequence

ENSEMBL: ENSMUSP00000151534 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000001179] [ENSMUST00000217838]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000001179
AA Change: C1401S

PolyPhen 2 Score 0.900 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000001179
Gene: ENSMUSG00000001151
AA Change: C1401S

Domain	Start	End	E-Value	Type
internal_repeat_1	7	78	2.47e-5	PROSPERO
low complexity region	104	114	N/A	INTRINSIC
coiled coil region	131	229	N/A	INTRINSIC
internal_repeat_3	241	259	6.69e-5	PROSPERO
low complexity region	313	325	N/A	INTRINSIC
internal_repeat_3	391	409	6.69e-5	PROSPERO
low complexity region	456	467	N/A	INTRINSIC
coiled coil region	468	520	N/A	INTRINSIC
coiled coil region	554	581	N/A	INTRINSIC
low complexity region	652	666	N/A	INTRINSIC
coiled coil region	727	787	N/A	INTRINSIC
coiled coil region	871	916	N/A	INTRINSIC
low complexity region	931	942	N/A	INTRINSIC
low complexity region	969	985	N/A	INTRINSIC
coiled coil region	1055	1383	N/A	INTRINSIC
coiled coil region	1429	1481	N/A	INTRINSIC
coiled coil region	1529	1567	N/A	INTRINSIC
low complexity region	1614	1624	N/A	INTRINSIC
internal_repeat_2	1916	1964	2.47e-5	PROSPERO
coiled coil region	2158	2178	N/A	INTRINSIC
coiled coil region	2211	2279	N/A	INTRINSIC
coiled coil region	2300	2421	N/A	INTRINSIC
coiled coil region	2447	2526	N/A	INTRINSIC
Pfam:PACT_coil_coil	2718	2797	5.8e-29	PFAM
internal_repeat_1	2820	2885	2.47e-5	PROSPERO
internal_repeat_2	2844	2891	2.47e-5	PROSPERO

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000187079

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000190491

Predicted Effect

possibly damaging
Transcript: ENSMUST00000217838
AA Change: C1401S

PolyPhen 2 Score 0.955 (Sensitivity: 0.79; Specificity: 0.95)

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000219701

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000220395

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.4%
20x: 92.8%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a gene trapped allele display mitotic spindle misorientation, microcephaly, craniofacial developmental anomalies, such as cleft palate and eye defects, variable structural kidney and cardiovascular defects, and altered hemodynamics leading to heart failure and prenatal lethality. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 88 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1300017J02Rik	A	G	9: 103,279,414 (GRCm38)	V149A	probably benign	Het
1700012B07Rik	G	T	11: 109,794,154 (GRCm38)	C172*	probably null	Het
4931406P16Rik	C	T	7: 34,245,812 (GRCm38)	G336S	probably benign	Het
9930111J21Rik1	G	A	11: 48,947,706 (GRCm38)	R685W	probably damaging	Het
Arhgap10	A	T	8: 77,382,757 (GRCm38)	L399H	probably damaging	Het
Arih2	AGCCG	AG	9: 108,611,660 (GRCm38)		probably benign	Het
Atp13a2	A	G	4: 141,000,821 (GRCm38)	H575R	possibly damaging	Het
Bbof1	G	A	12: 84,411,270 (GRCm38)		probably null	Het
Catsperg2	A	C	7: 29,710,134 (GRCm38)	Y545D	possibly damaging	Het
Cdc42bpa	T	A	1: 180,065,015 (GRCm38)	I248N	probably damaging	Het
Cdk11b	A	T	4: 155,648,825 (GRCm38)		probably benign	Het
Cfap46	C	A	7: 139,603,860 (GRCm38)	L90F	probably benign	Het
Cndp2	A	G	18: 84,670,829 (GRCm38)	L276P	possibly damaging	Het
Col3a1	A	C	1: 45,346,110 (GRCm38)	D129A	probably damaging	Het
Daam1	C	A	12: 71,946,520 (GRCm38)	H354Q	unknown	Het
Dnah5	T	A	15: 28,421,678 (GRCm38)	F3892Y	probably damaging	Het
Dnajb3	A	G	1: 88,205,023 (GRCm38)	V219A	possibly damaging	Het
Drd5	A	G	5: 38,320,201 (GRCm38)	H179R	probably damaging	Het
Dym	A	G	18: 75,119,161 (GRCm38)	N333D	possibly damaging	Het
Eif2b3	A	G	4: 117,052,736 (GRCm38)	D156G	probably damaging	Het
Emc1	A	G	4: 139,371,696 (GRCm38)	D830G	probably damaging	Het
F13a1	A	C	13: 36,988,856 (GRCm38)	I183M	probably damaging	Het
Fam136b-ps	T	A	15: 31,276,897 (GRCm38)		probably benign	Het
Fdft1	C	A	14: 63,163,404 (GRCm38)	K93N	probably damaging	Het
Gcc2	A	G	10: 58,278,806 (GRCm38)	D959G	probably damaging	Het
Gm14085	T	A	2: 122,522,914 (GRCm38)		probably null	Het
Gm853	C	T	4: 130,221,615 (GRCm38)		probably null	Het
Gp2	A	G	7: 119,454,291 (GRCm38)	V149A	probably damaging	Het
Gpc1	G	A	1: 92,857,029 (GRCm38)	G308D	probably damaging	Het
Hdac9	A	T	12: 34,373,907 (GRCm38)	C587S	probably benign	Het
Hspg2	C	T	4: 137,518,940 (GRCm38)	R1010C	probably damaging	Het
Iars2	A	G	1: 185,317,928 (GRCm38)	V453A	possibly damaging	Het
Il1r1	T	G	1: 40,293,524 (GRCm38)	C121W	probably damaging	Het
Jazf1	A	G	6: 52,777,540 (GRCm38)	Y184H	probably damaging	Het
Kel	A	T	6: 41,699,055 (GRCm38)	Y234N	probably damaging	Het
Khk	G	A	5: 30,929,660 (GRCm38)	G186D	probably damaging	Het
Klf4	A	T	4: 55,530,301 (GRCm38)	M270K	probably benign	Het
Kmt2c	G	A	5: 25,314,708 (GRCm38)	L2135F	probably benign	Het
Krtap15	A	G	16: 88,829,156 (GRCm38)	Y37C	probably damaging	Het
Lars	A	G	18: 42,214,776 (GRCm38)	F994S	possibly damaging	Het
Lrp8	T	C	4: 107,834,755 (GRCm38)		probably null	Het
Lrrc2	A	T	9: 110,980,919 (GRCm38)	D341V	probably damaging	Het
Map4k4	A	G	1: 40,007,502 (GRCm38)	K646R	probably damaging	Het
Mrps9	T	A	1: 42,895,331 (GRCm38)		probably null	Het
Olfr1130	T	A	2: 87,607,711 (GRCm38)	C108S	probably damaging	Het
Olfr745	T	A	14: 50,643,162 (GRCm38)	Y288N	probably damaging	Het
Olfr898	C	T	9: 38,349,628 (GRCm38)	H176Y	probably damaging	Het
Pdgfrb	A	T	18: 61,077,668 (GRCm38)	K749M	probably damaging	Het
Pigo	A	T	4: 43,019,412 (GRCm38)	W969R	probably null	Het
Pigr	A	T	1: 130,844,699 (GRCm38)	Y218F	probably damaging	Het
Pih1d1	A	G	7: 45,154,854 (GRCm38)		probably benign	Het
Pik3cg	A	T	12: 32,199,196 (GRCm38)		probably null	Het
Pik3r6	A	T	11: 68,533,468 (GRCm38)	K300*	probably null	Het
Pip5k1c	A	G	10: 81,305,250 (GRCm38)	D64G	probably damaging	Het
Piwil2	A	T	14: 70,421,593 (GRCm38)	I161K	possibly damaging	Het
Pou3f1	A	G	4: 124,658,656 (GRCm38)	E317G	probably damaging	Het
Prdm8	C	T	5: 98,185,212 (GRCm38)	Q213*	probably null	Het
Prpf6	T	A	2: 181,650,106 (GRCm38)	C739S	possibly damaging	Het
Psmc3	T	A	2: 91,054,608 (GRCm38)	S40T	probably benign	Het
Psmd3	A	T	11: 98,682,824 (GRCm38)	D32V	probably damaging	Het
Ptpro	T	A	6: 137,443,594 (GRCm38)	V1007D	probably damaging	Het
Rapgef6	A	T	11: 54,691,381 (GRCm38)	H1373L	possibly damaging	Het
Rnf207	A	C	4: 152,313,209 (GRCm38)	S328A	probably benign	Het
Ros1	C	T	10: 52,128,416 (GRCm38)		probably null	Het
Ryr2	T	A	13: 11,587,254 (GRCm38)	I4581F	possibly damaging	Het
Sacm1l	C	T	9: 123,586,399 (GRCm38)	R480W	probably damaging	Het
Sec16a	A	G	2: 26,419,649 (GRCm38)	V664A	probably benign	Het
Selenoo	T	A	15: 89,092,766 (GRCm38)	M207K	probably damaging	Het
Sh3tc2	G	A	18: 62,014,891 (GRCm38)		probably null	Het
Slco2b1	G	T	7: 99,660,049 (GRCm38)	Q692K	probably benign	Het
Slfn4	A	T	11: 83,186,797 (GRCm38)	D137V	probably damaging	Het
Srrm2	G	A	17: 23,820,618 (GRCm38)	A2175T	probably damaging	Het
Stard9	T	A	2: 120,693,399 (GRCm38)	C692S	probably benign	Het
Sulf2	T	A	2: 166,081,622 (GRCm38)	D559V	probably benign	Het
Tbpl2	T	C	2: 24,087,158 (GRCm38)	I283V	probably benign	Het
Tmem19	A	G	10: 115,359,761 (GRCm38)	F46S	probably benign	Het
Trp63	T	A	16: 25,763,306 (GRCm38)	Y35N	probably damaging	Het
Ttn	T	A	2: 76,886,442 (GRCm38)		probably benign	Het
Ube2z	A	T	11: 96,050,322 (GRCm38)	H331Q	probably benign	Het
Ubr1	C	T	2: 120,911,997 (GRCm38)		probably null	Het
Uhrf1bp1	A	G	17: 27,886,864 (GRCm38)	E788G	probably damaging	Het
Vmn1r235	A	T	17: 21,262,288 (GRCm38)	I292F	possibly damaging	Het
Vmn2r1	T	A	3: 64,105,080 (GRCm38)	D787E	probably damaging	Het
Vmn2r3	A	G	3: 64,259,799 (GRCm38)	V637A	probably benign	Het
Xpnpep1	C	A	19: 53,006,175 (GRCm38)	V341L	probably benign	Het
Yme1l1	A	G	2: 23,194,747 (GRCm38)	D619G	probably damaging	Het
Zfp597	G	A	16: 3,866,638 (GRCm38)	P85S	probably damaging	Het
Zscan20	A	G	4: 128,586,128 (GRCm38)	S857P	probably benign	Het

Other mutations in Pcnt

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01075:Pcnt	APN	10	76,422,904 (GRCm38)	nonsense	probably null
IGL01307:Pcnt	APN	10	76,411,588 (GRCm38)	missense	probably damaging	1.00
IGL01549:Pcnt	APN	10	76,367,486 (GRCm38)	splice site	probably null
IGL01576:Pcnt	APN	10	76,368,822 (GRCm38)	missense	probably damaging	0.99
IGL01611:Pcnt	APN	10	76,436,424 (GRCm38)	critical splice donor site	probably null
IGL01630:Pcnt	APN	10	76,420,246 (GRCm38)	missense	probably damaging	0.99
IGL01647:Pcnt	APN	10	76,370,001 (GRCm38)	nonsense	probably null
IGL01689:Pcnt	APN	10	76,411,653 (GRCm38)	missense	probably damaging	1.00
IGL01690:Pcnt	APN	10	76,392,775 (GRCm38)	missense	probably damaging	1.00
IGL01723:Pcnt	APN	10	76,418,499 (GRCm38)	missense	possibly damaging	0.63
IGL01920:Pcnt	APN	10	76,404,528 (GRCm38)	missense	probably damaging	1.00
IGL01958:Pcnt	APN	10	76,433,679 (GRCm38)	missense	probably damaging	0.96
IGL02210:Pcnt	APN	10	76,389,219 (GRCm38)	missense	possibly damaging	0.95
IGL02225:Pcnt	APN	10	76,389,474 (GRCm38)	missense	probably benign	0.00
IGL02228:Pcnt	APN	10	76,389,474 (GRCm38)	missense	probably benign	0.00
IGL02237:Pcnt	APN	10	76,352,984 (GRCm38)	missense	probably damaging	1.00
IGL02279:Pcnt	APN	10	76,403,765 (GRCm38)	missense	probably damaging	1.00
IGL02303:Pcnt	APN	10	76,442,559 (GRCm38)	splice site	probably benign
IGL02355:Pcnt	APN	10	76,375,162 (GRCm38)	nonsense	probably null
IGL02362:Pcnt	APN	10	76,375,162 (GRCm38)	nonsense	probably null
IGL02428:Pcnt	APN	10	76,429,256 (GRCm38)	missense	probably damaging	0.99
IGL02536:Pcnt	APN	10	76,380,229 (GRCm38)	missense	possibly damaging	0.68
IGL02715:Pcnt	APN	10	76,368,722 (GRCm38)	splice site	probably benign
IGL02800:Pcnt	APN	10	76,412,583 (GRCm38)	nonsense	probably null
IGL03395:Pcnt	APN	10	76,436,491 (GRCm38)	missense	possibly damaging	0.95
IGL02799:Pcnt	UTSW	10	76,412,583 (GRCm38)	nonsense	probably null
PIT4520001:Pcnt	UTSW	10	76,420,235 (GRCm38)	missense	probably damaging	0.99
R0049:Pcnt	UTSW	10	76,369,821 (GRCm38)	unclassified	probably benign
R0049:Pcnt	UTSW	10	76,369,821 (GRCm38)	unclassified	probably benign
R0109:Pcnt	UTSW	10	76,389,196 (GRCm38)	missense	probably benign	0.00
R0117:Pcnt	UTSW	10	76,408,727 (GRCm38)	nonsense	probably null
R0254:Pcnt	UTSW	10	76,392,580 (GRCm38)	missense	probably benign	0.10
R0392:Pcnt	UTSW	10	76,384,826 (GRCm38)	missense	probably benign
R0511:Pcnt	UTSW	10	76,404,595 (GRCm38)	missense	possibly damaging	0.66
R0570:Pcnt	UTSW	10	76,412,107 (GRCm38)	missense	probably damaging	1.00
R0614:Pcnt	UTSW	10	76,420,316 (GRCm38)	missense	probably damaging	1.00
R0635:Pcnt	UTSW	10	76,404,585 (GRCm38)	missense	probably damaging	1.00
R0707:Pcnt	UTSW	10	76,420,541 (GRCm38)	missense	probably damaging	1.00
R0749:Pcnt	UTSW	10	76,381,364 (GRCm38)	missense	probably damaging	1.00
R0969:Pcnt	UTSW	10	76,427,951 (GRCm38)	missense	probably damaging	1.00
R1172:Pcnt	UTSW	10	76,393,044 (GRCm38)	splice site	probably null
R1174:Pcnt	UTSW	10	76,393,044 (GRCm38)	splice site	probably null
R1175:Pcnt	UTSW	10	76,393,044 (GRCm38)	splice site	probably null
R1512:Pcnt	UTSW	10	76,404,662 (GRCm38)	splice site	probably null
R1542:Pcnt	UTSW	10	76,401,386 (GRCm38)	missense	probably benign	0.02
R1542:Pcnt	UTSW	10	76,389,387 (GRCm38)	missense	probably benign	0.08
R1558:Pcnt	UTSW	10	76,422,922 (GRCm38)	missense	possibly damaging	0.53
R1562:Pcnt	UTSW	10	76,367,330 (GRCm38)	missense	probably benign	0.02
R1762:Pcnt	UTSW	10	76,355,137 (GRCm38)	critical splice acceptor site	probably null
R1779:Pcnt	UTSW	10	76,408,796 (GRCm38)	missense	probably damaging	0.99
R1869:Pcnt	UTSW	10	76,379,906 (GRCm38)	missense	probably null	0.94
R1911:Pcnt	UTSW	10	76,368,816 (GRCm38)	missense	possibly damaging	0.94
R1985:Pcnt	UTSW	10	76,380,337 (GRCm38)	missense	possibly damaging	0.95
R1995:Pcnt	UTSW	10	76,392,799 (GRCm38)	nonsense	probably null
R2073:Pcnt	UTSW	10	76,380,380 (GRCm38)	missense	possibly damaging	0.92
R2111:Pcnt	UTSW	10	76,420,526 (GRCm38)	missense	probably damaging	0.99
R2112:Pcnt	UTSW	10	76,420,526 (GRCm38)	missense	probably damaging	0.99
R2309:Pcnt	UTSW	10	76,442,626 (GRCm38)	start gained	probably benign
R2902:Pcnt	UTSW	10	76,375,230 (GRCm38)	missense	probably damaging	0.98
R3623:Pcnt	UTSW	10	76,433,750 (GRCm38)	missense	probably benign	0.23
R4088:Pcnt	UTSW	10	76,428,014 (GRCm38)	missense	probably damaging	1.00
R4300:Pcnt	UTSW	10	76,367,391 (GRCm38)	missense	probably benign	0.40
R4402:Pcnt	UTSW	10	76,392,393 (GRCm38)	missense	probably benign	0.00
R4407:Pcnt	UTSW	10	76,374,870 (GRCm38)	missense	possibly damaging	0.90
R4483:Pcnt	UTSW	10	76,401,483 (GRCm38)	missense	probably damaging	1.00
R4647:Pcnt	UTSW	10	76,354,213 (GRCm38)	missense	probably benign	0.01
R4734:Pcnt	UTSW	10	76,437,206 (GRCm38)	missense	probably benign	0.25
R4747:Pcnt	UTSW	10	76,436,465 (GRCm38)	missense	possibly damaging	0.91
R4782:Pcnt	UTSW	10	76,409,577 (GRCm38)	missense	possibly damaging	0.62
R4795:Pcnt	UTSW	10	76,370,024 (GRCm38)	missense	probably benign	0.21
R4831:Pcnt	UTSW	10	76,412,501 (GRCm38)	missense	probably damaging	0.96
R4873:Pcnt	UTSW	10	76,369,854 (GRCm38)	missense	probably benign	0.03
R4875:Pcnt	UTSW	10	76,369,854 (GRCm38)	missense	probably benign	0.03
R4946:Pcnt	UTSW	10	76,356,185 (GRCm38)	missense	probably damaging	1.00
R5032:Pcnt	UTSW	10	76,355,077 (GRCm38)	missense	probably benign	0.00
R5106:Pcnt	UTSW	10	76,401,444 (GRCm38)	missense	probably damaging	1.00
R5118:Pcnt	UTSW	10	76,412,168 (GRCm38)	missense	probably damaging	0.98
R5167:Pcnt	UTSW	10	76,420,424 (GRCm38)	missense	probably damaging	0.97
R5199:Pcnt	UTSW	10	76,418,544 (GRCm38)	missense	probably benign	0.09
R5223:Pcnt	UTSW	10	76,380,272 (GRCm38)	missense	probably damaging	0.99
R5241:Pcnt	UTSW	10	76,433,617 (GRCm38)	missense	probably benign	0.26
R5308:Pcnt	UTSW	10	76,356,325 (GRCm38)	nonsense	probably null
R5328:Pcnt	UTSW	10	76,411,719 (GRCm38)	missense	probably damaging	1.00
R5454:Pcnt	UTSW	10	76,389,547 (GRCm38)	splice site	probably null
R5543:Pcnt	UTSW	10	76,412,052 (GRCm38)	missense	probably benign	0.01
R5588:Pcnt	UTSW	10	76,442,611 (GRCm38)	missense	possibly damaging	0.74
R5647:Pcnt	UTSW	10	76,385,841 (GRCm38)	missense	probably benign	0.17
R5668:Pcnt	UTSW	10	76,409,500 (GRCm38)	missense	probably benign	0.16
R5712:Pcnt	UTSW	10	76,429,271 (GRCm38)	missense	probably damaging	0.96
R5714:Pcnt	UTSW	10	76,420,491 (GRCm38)	missense	probably damaging	1.00
R5797:Pcnt	UTSW	10	76,392,756 (GRCm38)	missense	probably benign	0.00
R5946:Pcnt	UTSW	10	76,382,063 (GRCm38)	missense	possibly damaging	0.91
R5955:Pcnt	UTSW	10	76,411,622 (GRCm38)	missense	possibly damaging	0.45
R6024:Pcnt	UTSW	10	76,420,037 (GRCm38)	missense	possibly damaging	0.87
R6267:Pcnt	UTSW	10	76,385,798 (GRCm38)	missense	probably benign	0.02
R6485:Pcnt	UTSW	10	76,389,330 (GRCm38)	nonsense	probably null
R6605:Pcnt	UTSW	10	76,429,198 (GRCm38)	critical splice donor site	probably null
R6877:Pcnt	UTSW	10	76,434,017 (GRCm38)	missense	possibly damaging	0.94
R6882:Pcnt	UTSW	10	76,427,828 (GRCm38)	missense	probably benign	0.00
R6919:Pcnt	UTSW	10	76,385,798 (GRCm38)	missense	probably benign	0.02
R7025:Pcnt	UTSW	10	76,403,835 (GRCm38)	missense	probably damaging	1.00
R7098:Pcnt	UTSW	10	76,384,839 (GRCm38)	missense	probably benign
R7109:Pcnt	UTSW	10	76,369,904 (GRCm38)	missense	probably damaging	1.00
R7121:Pcnt	UTSW	10	76,427,927 (GRCm38)	missense	possibly damaging	0.73
R7143:Pcnt	UTSW	10	76,389,060 (GRCm38)	missense	possibly damaging	0.47
R7152:Pcnt	UTSW	10	76,411,360 (GRCm38)	splice site	probably null
R7213:Pcnt	UTSW	10	76,408,904 (GRCm38)	missense	probably damaging	1.00
R7368:Pcnt	UTSW	10	76,400,001 (GRCm38)	missense	probably benign
R7453:Pcnt	UTSW	10	76,389,450 (GRCm38)	missense	probably benign
R7486:Pcnt	UTSW	10	76,418,437 (GRCm38)	missense	probably benign
R7486:Pcnt	UTSW	10	76,418,436 (GRCm38)	missense	probably benign	0.03
R7538:Pcnt	UTSW	10	76,399,939 (GRCm38)	missense	probably benign
R7575:Pcnt	UTSW	10	76,389,252 (GRCm38)	missense	probably benign	0.32
R7662:Pcnt	UTSW	10	76,387,522 (GRCm38)	missense	probably benign	0.27
R7685:Pcnt	UTSW	10	76,422,808 (GRCm38)	missense	probably benign	0.14
R7764:Pcnt	UTSW	10	76,354,248 (GRCm38)	missense	probably benign	0.33
R7802:Pcnt	UTSW	10	76,375,303 (GRCm38)	splice site	probably null
R8432:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8439:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8493:Pcnt	UTSW	10	76,403,623 (GRCm38)	critical splice donor site	probably null
R8530:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8535:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8830:Pcnt	UTSW	10	76,382,174 (GRCm38)	missense	probably benign	0.03
R8878:Pcnt	UTSW	10	76,408,841 (GRCm38)	missense	probably damaging	1.00
R8911:Pcnt	UTSW	10	76,387,525 (GRCm38)	missense	probably damaging	0.98
R8988:Pcnt	UTSW	10	76,409,573 (GRCm38)	nonsense	probably null
R9084:Pcnt	UTSW	10	76,399,992 (GRCm38)	missense	probably benign	0.09
R9169:Pcnt	UTSW	10	76,385,738 (GRCm38)	missense	possibly damaging	0.95
R9372:Pcnt	UTSW	10	76,423,126 (GRCm38)	missense	probably damaging	1.00
R9411:Pcnt	UTSW	10	76,423,062 (GRCm38)	missense	probably damaging	0.96
R9448:Pcnt	UTSW	10	76,420,526 (GRCm38)	missense	probably damaging	0.99
R9459:Pcnt	UTSW	10	76,392,738 (GRCm38)	missense	probably damaging	1.00
R9479:Pcnt	UTSW	10	76,382,129 (GRCm38)	missense	probably benign	0.00
R9503:Pcnt	UTSW	10	76,428,048 (GRCm38)	missense	possibly damaging	0.59
R9561:Pcnt	UTSW	10	76,381,294 (GRCm38)	nonsense	probably null
R9618:Pcnt	UTSW	10	76,352,960 (GRCm38)	missense	probably damaging	1.00
R9648:Pcnt	UTSW	10	76,354,255 (GRCm38)	missense	probably benign	0.32
R9733:Pcnt	UTSW	10	76,401,480 (GRCm38)	missense	probably benign	0.01
Z1176:Pcnt	UTSW	10	76,382,157 (GRCm38)	nonsense	probably null
Z1177:Pcnt	UTSW	10	76,399,968 (GRCm38)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- ATAAACTCTGGCCACAGTGCTG -3'
(R):5'- ACTTCTGCAGGAGACCTCATG -3'

Sequencing Primer
(F):5'- ATGGTGAGCCTTTATGCAGAAG -3'
(R):5'- GGAGACCTCATGCTGGCTTATAAC -3'

Posted On

2016-06-06