Mutagenetix > Incidental Mutation

Incidental Mutation 'R5036:Gm4781'

389542

Institutional Source

Beutler Lab

Gene Symbol

Gm4781

Ensembl Gene

ENSMUSG00000090987

Gene Name

predicted gene 4781

Synonyms

MMRRC Submission

042627-MU

Accession Numbers

Essential gene?

Not available question?

Stock #

R5036 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

100232275-100232925 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

C to A at 100232851 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000167995

SMART Domains

Protein: ENSMUSP00000132273
Gene: ENSMUSG00000090987

Domain	Start	End	E-Value	Type
Pfam:FYTT	1	52	6e-8	PFAM
RRM	87	159	9.63e-17	SMART
coiled coil region	209	261	N/A	INTRINSIC

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.0%
3x: 98.2%
10x: 95.7%
20x: 90.1%

Validation Efficiency

100% (44/44)

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610021A01Rik	G	A	7: 41,275,578 (GRCm39)	G427D	possibly damaging	Het
Agbl5	G	A	5: 31,060,403 (GRCm39)	R141Q	probably damaging	Het
C4b	T	A	17: 34,959,419 (GRCm39)		probably null	Het
Cabyr	A	T	18: 12,884,303 (GRCm39)	E263D	probably damaging	Het
Car1	A	T	3: 14,841,299 (GRCm39)	D45E	possibly damaging	Het
Col25a1	T	C	3: 130,376,978 (GRCm39)		probably null	Het
Dnah6	G	T	6: 73,021,674 (GRCm39)	S3549R	probably benign	Het
Dync1h1	A	T	12: 110,596,969 (GRCm39)	I1639F	probably damaging	Het
Fhad1	A	T	4: 141,648,052 (GRCm39)	D271E	probably benign	Het
Gle1	T	C	2: 29,826,223 (GRCm39)	S101P	probably benign	Het
Gpatch3	A	G	4: 133,305,461 (GRCm39)	Y232C	probably damaging	Het
Gtf2ird2	A	G	5: 134,246,349 (GRCm39)	N869S	probably damaging	Het
Ifi204	G	A	1: 173,580,311 (GRCm39)	P400S	possibly damaging	Het
Ighv2-2	T	C	12: 113,552,092 (GRCm39)	T49A	possibly damaging	Het
Itsn1	T	A	16: 91,579,123 (GRCm39)		probably benign	Het
Mib2	A	T	4: 155,740,745 (GRCm39)	N626K	probably damaging	Het
Nf1	C	A	11: 79,337,690 (GRCm39)	Q1098K	probably damaging	Het
Odc1	C	A	12: 17,598,020 (GRCm39)	Q116K	probably damaging	Het
Otof	C	T	5: 30,541,783 (GRCm39)	E761K	possibly damaging	Het
Palld	A	T	8: 62,003,196 (GRCm39)	V301D	probably damaging	Het
Pask	A	T	1: 93,249,801 (GRCm39)	L533*	probably null	Het
Plekhh2	T	C	17: 84,879,189 (GRCm39)	S638P	probably damaging	Het
Scaf8	T	A	17: 3,214,537 (GRCm39)		probably benign	Het
Sdccag8	G	T	1: 176,839,541 (GRCm39)	R695L	probably damaging	Het
Serpina1c	A	G	12: 103,865,085 (GRCm39)	I187T	probably damaging	Het
Slitrk5	G	T	14: 111,918,316 (GRCm39)	G647W	possibly damaging	Het
Sycp1	T	A	3: 102,727,916 (GRCm39)	K899M	probably damaging	Het
Taok1	G	A	11: 77,440,157 (GRCm39)	R617C	probably benign	Het
Tbc1d32	A	C	10: 56,071,500 (GRCm39)	Y341*	probably null	Het
Tenm4	A	G	7: 96,343,997 (GRCm39)	N267D	probably damaging	Het
Tenm4	T	C	7: 96,501,768 (GRCm39)	V1287A	probably damaging	Het
Tsga10	A	T	1: 37,823,049 (GRCm39)	V488E	possibly damaging	Het
Ttc39c	G	T	18: 12,820,138 (GRCm39)		probably null	Het
Uck1	A	T	2: 32,148,478 (GRCm39)		probably benign	Het
Vmn2r98	A	G	17: 19,286,419 (GRCm39)	I306V	probably benign	Het

Other mutations in Gm4781

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02321:Gm4781	APN	10	100,232,752 (GRCm39)	exon	noncoding transcript
IGL02583:Gm4781	APN	10	100,232,507 (GRCm39)	exon	noncoding transcript
R0731:Gm4781	UTSW	10	100,232,639 (GRCm39)	exon	noncoding transcript
R1686:Gm4781	UTSW	10	100,232,837 (GRCm39)	exon	noncoding transcript
R1836:Gm4781	UTSW	10	100,232,582 (GRCm39)	exon	noncoding transcript
R2147:Gm4781	UTSW	10	100,232,414 (GRCm39)	exon	noncoding transcript
R4647:Gm4781	UTSW	10	100,232,862 (GRCm39)	exon	noncoding transcript
R5039:Gm4781	UTSW	10	100,232,851 (GRCm39)	exon	noncoding transcript
R5777:Gm4781	UTSW	10	100,232,831 (GRCm39)	exon	noncoding transcript
R5793:Gm4781	UTSW	10	100,232,529 (GRCm39)	exon	noncoding transcript
R5966:Gm4781	UTSW	10	100,232,814 (GRCm39)	exon	noncoding transcript
R6180:Gm4781	UTSW	10	100,232,349 (GRCm39)	exon	noncoding transcript
R8227:Gm4781	UTSW	10	100,232,424 (GRCm39)	missense	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TGACAGGAACAGCTTCCCAC -3'
(R):5'- CCTAATCAGGTTCTCAGGATCTC -3'

Sequencing Primer
(F):5'- ACCAGTATCCACGTCGTTTTGAC -3'
(R):5'- GATCTCTTCCTTATGCCTTAATGATG -3'

Posted On

2016-06-06