Incidental Mutation 'R0433:Myh15'
| ID |
38972 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh15
|
| Ensembl Gene |
ENSMUSG00000092009 |
| Gene Name |
myosin, heavy chain 15 |
| Synonyms |
EG667772 |
| MMRRC Submission |
038635-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R0433 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
48877849-49019467 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 48965599 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1168
(D1168G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127539
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168680]
|
| AlphaFold |
E9Q264 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000168680
AA Change: D1168G
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000127539
Gene: ENSMUSG00000092009
AA Change: D1168G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
30 |
70 |
5.2e-12 |
PFAM |
|
MYSc
|
76 |
770 |
N/A |
SMART |
|
Pfam:Myosin_tail_1
|
836 |
1915 |
9.5e-118 |
PFAM |
|
| Meta Mutation Damage Score |
0.4343 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 94.3%
|
| Validation Efficiency |
99% (108/109) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110032F04Rik |
T |
C |
3: 68,777,636 (GRCm39) |
V199A |
possibly damaging |
Het |
| Abcb5 |
T |
C |
12: 118,841,545 (GRCm39) |
M967V |
probably benign |
Het |
| Adcy10 |
T |
A |
1: 165,379,591 (GRCm39) |
L951Q |
probably damaging |
Het |
| Amer2 |
A |
T |
14: 60,616,032 (GRCm39) |
S76C |
probably damaging |
Het |
| Atad1 |
T |
C |
19: 32,675,877 (GRCm39) |
I182M |
probably benign |
Het |
| Bpi |
A |
G |
2: 158,100,339 (GRCm39) |
D42G |
probably damaging |
Het |
| C7 |
G |
T |
15: 5,018,398 (GRCm39) |
T815K |
probably damaging |
Het |
| Cacna1g |
T |
A |
11: 94,350,033 (GRCm39) |
D604V |
probably benign |
Het |
| Camk1g |
A |
G |
1: 193,036,366 (GRCm39) |
F165L |
probably damaging |
Het |
| Ccdc69 |
C |
T |
11: 54,943,716 (GRCm39) |
|
probably null |
Het |
| Ccser2 |
A |
C |
14: 36,640,486 (GRCm39) |
F37L |
probably damaging |
Het |
| Cfap43 |
A |
G |
19: 47,814,210 (GRCm39) |
F208S |
probably benign |
Het |
| Cfap54 |
G |
A |
10: 92,814,942 (GRCm39) |
|
probably benign |
Het |
| Cfap69 |
A |
C |
5: 5,699,853 (GRCm39) |
D62E |
probably damaging |
Het |
| Cnksr2 |
A |
T |
X: 156,671,554 (GRCm39) |
M483K |
probably benign |
Het |
| Cnksr2 |
C |
A |
X: 156,671,553 (GRCm39) |
M483I |
probably benign |
Het |
| Cog8 |
T |
C |
8: 107,783,110 (GRCm39) |
S60G |
possibly damaging |
Het |
| Col4a3 |
C |
T |
1: 82,647,940 (GRCm39) |
P484S |
unknown |
Het |
| Col6a4 |
C |
T |
9: 105,945,193 (GRCm39) |
G974R |
probably damaging |
Het |
| Cplane1 |
T |
C |
15: 8,246,046 (GRCm39) |
S1473P |
probably benign |
Het |
| Dbnl |
T |
G |
11: 5,746,825 (GRCm39) |
|
probably null |
Het |
| Dhcr7 |
T |
C |
7: 143,394,200 (GRCm39) |
C114R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,350,114 (GRCm39) |
D2340Y |
probably damaging |
Het |
| Dnai4 |
T |
C |
4: 102,960,450 (GRCm39) |
N67D |
probably benign |
Het |
| Dusp10 |
T |
A |
1: 183,801,393 (GRCm39) |
Y387N |
probably damaging |
Het |
| Eipr1 |
C |
T |
12: 28,909,330 (GRCm39) |
T199I |
possibly damaging |
Het |
| Emc2 |
T |
G |
15: 43,360,520 (GRCm39) |
|
probably null |
Het |
| Enpp3 |
A |
G |
10: 24,696,495 (GRCm39) |
S147P |
probably benign |
Het |
| Fam133b |
T |
A |
5: 3,608,560 (GRCm39) |
|
probably benign |
Het |
| Fat1 |
C |
A |
8: 45,477,686 (GRCm39) |
T2244K |
possibly damaging |
Het |
| Fbn1 |
A |
G |
2: 125,190,135 (GRCm39) |
S1453P |
possibly damaging |
Het |
| Fez2 |
A |
T |
17: 78,725,476 (GRCm39) |
F13I |
probably damaging |
Het |
| Ggnbp2 |
T |
C |
11: 84,727,246 (GRCm39) |
K530R |
probably damaging |
Het |
| Gpa33 |
T |
C |
1: 165,991,330 (GRCm39) |
|
probably benign |
Het |
| Gpr142 |
T |
C |
11: 114,696,823 (GRCm39) |
I123T |
probably damaging |
Het |
| Il21 |
T |
G |
3: 37,286,684 (GRCm39) |
I11L |
possibly damaging |
Het |
| Klhl7 |
A |
G |
5: 24,332,700 (GRCm39) |
E86G |
probably damaging |
Het |
| Klk10 |
G |
T |
7: 43,430,989 (GRCm39) |
A11S |
possibly damaging |
Het |
| Knl1 |
A |
T |
2: 118,934,542 (GRCm39) |
D2115V |
probably damaging |
Het |
| Lonp2 |
A |
G |
8: 87,360,582 (GRCm39) |
D185G |
probably damaging |
Het |
| Lrrc47 |
T |
C |
4: 154,102,822 (GRCm39) |
|
probably benign |
Het |
| Lrrcc1 |
A |
G |
3: 14,624,434 (GRCm39) |
I698V |
probably damaging |
Het |
| Lzts2 |
T |
C |
19: 45,010,115 (GRCm39) |
V83A |
possibly damaging |
Het |
| Melk |
C |
A |
4: 44,340,614 (GRCm39) |
|
probably benign |
Het |
| Mical1 |
G |
A |
10: 41,355,486 (GRCm39) |
V150I |
probably benign |
Het |
| Morn3 |
C |
A |
5: 123,177,396 (GRCm39) |
M129I |
probably benign |
Het |
| Mroh2b |
T |
A |
15: 4,971,116 (GRCm39) |
D1040E |
probably benign |
Het |
| Mroh5 |
T |
C |
15: 73,661,877 (GRCm39) |
N438S |
probably benign |
Het |
| Mroh5 |
T |
A |
15: 73,662,657 (GRCm39) |
Q387L |
probably damaging |
Het |
| Nek10 |
A |
G |
14: 14,860,927 (GRCm38) |
E493G |
probably benign |
Het |
| Nipsnap3a |
A |
G |
4: 53,000,316 (GRCm39) |
Y227C |
probably damaging |
Het |
| Nlrp9c |
T |
A |
7: 26,085,244 (GRCm39) |
T112S |
probably benign |
Het |
| Nphp4 |
T |
C |
4: 152,602,629 (GRCm39) |
V401A |
probably benign |
Het |
| Nr1h2 |
A |
G |
7: 44,199,411 (GRCm39) |
*365Q |
probably null |
Het |
| Or13p5 |
T |
C |
4: 118,592,287 (GRCm39) |
V187A |
probably benign |
Het |
| Or5p54 |
T |
C |
7: 107,554,469 (GRCm39) |
I207T |
probably damaging |
Het |
| Pacs2 |
T |
A |
12: 113,020,464 (GRCm39) |
V279D |
possibly damaging |
Het |
| Pdcd2 |
C |
T |
17: 15,746,646 (GRCm39) |
C171Y |
probably benign |
Het |
| Pde11a |
T |
A |
2: 76,168,050 (GRCm39) |
D301V |
possibly damaging |
Het |
| Pfpl |
T |
G |
19: 12,406,839 (GRCm39) |
N363K |
probably damaging |
Het |
| Phf14 |
T |
A |
6: 11,933,742 (GRCm39) |
S201R |
probably damaging |
Het |
| Pip4k2c |
G |
A |
10: 127,044,815 (GRCm39) |
P66S |
probably benign |
Het |
| Pou2f3 |
G |
T |
9: 43,038,693 (GRCm39) |
H392N |
probably benign |
Het |
| Pou3f1 |
G |
T |
4: 124,552,697 (GRCm39) |
G400C |
probably damaging |
Het |
| Ptprg |
T |
C |
14: 12,220,620 (GRCm38) |
I1219T |
probably damaging |
Het |
| Rfx6 |
A |
G |
10: 51,596,124 (GRCm39) |
D435G |
probably damaging |
Het |
| Rhpn2 |
T |
A |
7: 35,084,899 (GRCm39) |
S598T |
probably benign |
Het |
| Sdccag8 |
C |
A |
1: 176,672,387 (GRCm39) |
|
probably null |
Het |
| Sec16b |
C |
A |
1: 157,362,279 (GRCm39) |
Y43* |
probably null |
Het |
| Sele |
T |
C |
1: 163,876,813 (GRCm39) |
Y30H |
possibly damaging |
Het |
| Sgsm2 |
C |
T |
11: 74,749,016 (GRCm39) |
|
probably null |
Het |
| Slc45a2 |
T |
C |
15: 11,025,831 (GRCm39) |
Y394H |
probably benign |
Het |
| Slc4a10 |
T |
G |
2: 62,120,327 (GRCm39) |
I788S |
probably benign |
Het |
| Slmap |
A |
T |
14: 26,174,749 (GRCm39) |
L161* |
probably null |
Het |
| Slx4 |
A |
T |
16: 3,803,882 (GRCm39) |
D977E |
probably benign |
Het |
| Spata31e5 |
A |
T |
1: 28,816,423 (GRCm39) |
Y536* |
probably null |
Het |
| Spata31f3 |
A |
G |
4: 42,874,013 (GRCm39) |
|
probably benign |
Het |
| Spen |
A |
T |
4: 141,211,069 (GRCm39) |
M608K |
unknown |
Het |
| St8sia4 |
G |
C |
1: 95,519,429 (GRCm39) |
T353R |
probably damaging |
Het |
| Stab2 |
G |
T |
10: 86,679,355 (GRCm39) |
|
probably benign |
Het |
| Stx12 |
C |
T |
4: 132,585,741 (GRCm39) |
G213D |
probably damaging |
Het |
| Synj2 |
A |
T |
17: 6,084,123 (GRCm39) |
N270Y |
probably damaging |
Het |
| Tdrd9 |
C |
T |
12: 111,992,015 (GRCm39) |
R438* |
probably null |
Het |
| Tert |
T |
C |
13: 73,775,200 (GRCm39) |
Y18H |
probably damaging |
Het |
| Tph1 |
A |
T |
7: 46,303,245 (GRCm39) |
F244L |
probably damaging |
Het |
| Triobp |
T |
C |
15: 78,852,401 (GRCm39) |
F852L |
possibly damaging |
Het |
| Trpv1 |
T |
C |
11: 73,143,834 (GRCm39) |
|
probably benign |
Het |
| Uggt2 |
A |
T |
14: 119,312,741 (GRCm39) |
|
probably null |
Het |
| Ulk4 |
A |
G |
9: 120,873,885 (GRCm39) |
I1182T |
probably benign |
Het |
| Uqcc1 |
A |
G |
2: 155,752,288 (GRCm39) |
Y98H |
probably damaging |
Het |
| Usp25 |
A |
G |
16: 76,906,105 (GRCm39) |
I854V |
probably benign |
Het |
| Usp50 |
T |
C |
2: 126,603,464 (GRCm39) |
S361G |
probably damaging |
Het |
| Uspl1 |
C |
A |
5: 149,151,625 (GRCm39) |
Q743K |
probably damaging |
Het |
| Vmn2r3 |
A |
G |
3: 64,183,054 (GRCm39) |
V215A |
possibly damaging |
Het |
| Vmn2r61 |
A |
T |
7: 41,915,335 (GRCm39) |
H94L |
probably benign |
Het |
| Vps37c |
T |
C |
19: 10,690,393 (GRCm39) |
V285A |
probably benign |
Het |
| Vwa8 |
T |
C |
14: 79,300,116 (GRCm39) |
V983A |
probably damaging |
Het |
| Zcchc9 |
C |
T |
13: 91,954,081 (GRCm39) |
R58H |
probably benign |
Het |
| Zdbf2 |
T |
C |
1: 63,345,302 (GRCm39) |
V1227A |
possibly damaging |
Het |
| Zfp292 |
T |
C |
4: 34,839,959 (GRCm39) |
K64E |
probably damaging |
Het |
| Zfp948 |
A |
G |
17: 21,807,764 (GRCm39) |
T319A |
probably benign |
Het |
| Zp3r |
T |
G |
1: 130,504,870 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Myh15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00943:Myh15
|
APN |
16 |
48,986,176 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01095:Myh15
|
APN |
16 |
48,952,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01343:Myh15
|
APN |
16 |
48,976,040 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01474:Myh15
|
APN |
16 |
48,952,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01572:Myh15
|
APN |
16 |
48,920,585 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01595:Myh15
|
APN |
16 |
48,993,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Myh15
|
APN |
16 |
48,881,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01638:Myh15
|
APN |
16 |
48,889,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01667:Myh15
|
APN |
16 |
49,015,942 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01715:Myh15
|
APN |
16 |
48,877,847 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01833:Myh15
|
APN |
16 |
48,934,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02004:Myh15
|
APN |
16 |
48,930,892 (GRCm39) |
splice site |
probably benign |
|
|
IGL02033:Myh15
|
APN |
16 |
48,965,707 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02148:Myh15
|
APN |
16 |
48,936,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Myh15
|
APN |
16 |
48,911,526 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02249:Myh15
|
APN |
16 |
48,930,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02505:Myh15
|
APN |
16 |
48,937,626 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02622:Myh15
|
APN |
16 |
48,997,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02814:Myh15
|
APN |
16 |
48,965,801 (GRCm39) |
splice site |
probably benign |
|
|
IGL02869:Myh15
|
APN |
16 |
48,965,767 (GRCm39) |
missense |
probably benign |
|
|
IGL02879:Myh15
|
APN |
16 |
48,993,422 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02881:Myh15
|
APN |
16 |
48,937,628 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03077:Myh15
|
APN |
16 |
48,916,901 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03354:Myh15
|
APN |
16 |
48,992,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03411:Myh15
|
APN |
16 |
48,980,330 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
ANU74:Myh15
|
UTSW |
16 |
48,993,295 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
P0027:Myh15
|
UTSW |
16 |
48,901,571 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
PIT1430001:Myh15
|
UTSW |
16 |
49,017,254 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0017:Myh15
|
UTSW |
16 |
48,983,423 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0038:Myh15
|
UTSW |
16 |
48,891,504 (GRCm39) |
splice site |
probably benign |
|
|
R0149:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0361:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0373:Myh15
|
UTSW |
16 |
49,003,322 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0525:Myh15
|
UTSW |
16 |
48,952,414 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0586:Myh15
|
UTSW |
16 |
48,992,250 (GRCm39) |
splice site |
probably benign |
|
|
R0601:Myh15
|
UTSW |
16 |
48,881,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0717:Myh15
|
UTSW |
16 |
48,963,356 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0963:Myh15
|
UTSW |
16 |
48,952,512 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1075:Myh15
|
UTSW |
16 |
48,940,417 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1143:Myh15
|
UTSW |
16 |
48,885,449 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1200:Myh15
|
UTSW |
16 |
48,916,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Myh15
|
UTSW |
16 |
48,952,566 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1646:Myh15
|
UTSW |
16 |
49,015,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Myh15
|
UTSW |
16 |
48,913,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1768:Myh15
|
UTSW |
16 |
48,983,498 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1881:Myh15
|
UTSW |
16 |
48,891,446 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2048:Myh15
|
UTSW |
16 |
48,975,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2064:Myh15
|
UTSW |
16 |
48,975,984 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2184:Myh15
|
UTSW |
16 |
48,957,874 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2212:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2216:Myh15
|
UTSW |
16 |
48,986,201 (GRCm39) |
nonsense |
probably null |
|
|
R2321:Myh15
|
UTSW |
16 |
48,933,436 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2327:Myh15
|
UTSW |
16 |
48,963,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2395:Myh15
|
UTSW |
16 |
48,889,877 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2399:Myh15
|
UTSW |
16 |
48,957,952 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3413:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4234:Myh15
|
UTSW |
16 |
48,983,405 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4382:Myh15
|
UTSW |
16 |
48,963,306 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4421:Myh15
|
UTSW |
16 |
48,929,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4580:Myh15
|
UTSW |
16 |
48,885,388 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4657:Myh15
|
UTSW |
16 |
48,992,421 (GRCm39) |
nonsense |
probably null |
|
|
R4780:Myh15
|
UTSW |
16 |
48,940,420 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5004:Myh15
|
UTSW |
16 |
48,952,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5175:Myh15
|
UTSW |
16 |
48,889,789 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5189:Myh15
|
UTSW |
16 |
48,921,870 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5311:Myh15
|
UTSW |
16 |
48,986,204 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5318:Myh15
|
UTSW |
16 |
48,930,834 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5404:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5415:Myh15
|
UTSW |
16 |
48,937,658 (GRCm39) |
missense |
probably null |
1.00 |
|
R5558:Myh15
|
UTSW |
16 |
48,889,900 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5977:Myh15
|
UTSW |
16 |
48,973,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6004:Myh15
|
UTSW |
16 |
48,980,062 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6275:Myh15
|
UTSW |
16 |
48,965,610 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6381:Myh15
|
UTSW |
16 |
48,921,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6448:Myh15
|
UTSW |
16 |
48,992,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6516:Myh15
|
UTSW |
16 |
48,957,996 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6752:Myh15
|
UTSW |
16 |
49,003,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6847:Myh15
|
UTSW |
16 |
48,965,451 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R6868:Myh15
|
UTSW |
16 |
48,889,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6889:Myh15
|
UTSW |
16 |
48,973,474 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6896:Myh15
|
UTSW |
16 |
48,933,434 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6955:Myh15
|
UTSW |
16 |
48,901,598 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6984:Myh15
|
UTSW |
16 |
48,930,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7046:Myh15
|
UTSW |
16 |
48,929,662 (GRCm39) |
nonsense |
probably null |
|
|
R7095:Myh15
|
UTSW |
16 |
48,992,272 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7098:Myh15
|
UTSW |
16 |
48,997,420 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7134:Myh15
|
UTSW |
16 |
48,901,705 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7159:Myh15
|
UTSW |
16 |
48,881,937 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7244:Myh15
|
UTSW |
16 |
49,017,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7278:Myh15
|
UTSW |
16 |
48,911,468 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7309:Myh15
|
UTSW |
16 |
48,916,828 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7327:Myh15
|
UTSW |
16 |
48,993,369 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7418:Myh15
|
UTSW |
16 |
48,975,900 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7937:Myh15
|
UTSW |
16 |
48,976,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8053:Myh15
|
UTSW |
16 |
48,963,302 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8313:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8315:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8316:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8317:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8342:Myh15
|
UTSW |
16 |
48,913,120 (GRCm39) |
missense |
probably benign |
|
|
R8379:Myh15
|
UTSW |
16 |
48,901,551 (GRCm39) |
missense |
probably benign |
|
|
R8445:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8707:Myh15
|
UTSW |
16 |
48,973,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8729:Myh15
|
UTSW |
16 |
48,881,851 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8773:Myh15
|
UTSW |
16 |
49,015,900 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8869:Myh15
|
UTSW |
16 |
48,997,366 (GRCm39) |
missense |
probably benign |
|
|
R8890:Myh15
|
UTSW |
16 |
48,959,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9026:Myh15
|
UTSW |
16 |
49,007,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Myh15
|
UTSW |
16 |
48,913,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9290:Myh15
|
UTSW |
16 |
48,997,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9710:Myh15
|
UTSW |
16 |
48,959,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0012:Myh15
|
UTSW |
16 |
48,963,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0020:Myh15
|
UTSW |
16 |
48,986,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Myh15
|
UTSW |
16 |
48,916,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Myh15
|
UTSW |
16 |
48,980,189 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1177:Myh15
|
UTSW |
16 |
48,975,981 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1177:Myh15
|
UTSW |
16 |
48,901,591 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGGGGAATCTGGAAGTACTGAAAATT -3'
(R):5'- GGAGGTCATCCACTTGAAGCTGC -3'
Sequencing Primer
(F):5'- CATGTTTGCTTTTGAAGTTGAGAC -3'
(R):5'- GCAGGTCACTCTTGTCTTGTTC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation