Mutagenetix > Incidental Mutation

Incidental Mutation 'R5009:Greb1'

390378

Institutional Source

Beutler Lab

Gene Symbol

Greb1

Ensembl Gene

ENSMUSG00000036523

Gene Name

gene regulated by estrogen in breast cancer protein

Synonyms

5730583K22Rik

MMRRC Submission

042600-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5009 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

16670615-16800886 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 16724857 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 180 (T180A)

Ref Sequence

ENSEMBL: ENSMUSP00000124348 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048064] [ENSMUST00000159120] [ENSMUST00000162112]

AlphaFold

Q3UHK3

Predicted Effect

possibly damaging
Transcript: ENSMUST00000048064
AA Change: T180A

PolyPhen 2 Score 0.786 (Sensitivity: 0.85; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000044454
Gene: ENSMUSG00000036523
AA Change: T180A

Domain	Start	End	E-Value	Type
Pfam:GREB1	1	1954	N/A	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000159120
AA Change: T180A

PolyPhen 2 Score 0.786 (Sensitivity: 0.85; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000125339
Gene: ENSMUSG00000036523
AA Change: T180A

Domain	Start	End	E-Value	Type
low complexity region	52	71	N/A	INTRINSIC
low complexity region	292	303	N/A	INTRINSIC
low complexity region	437	453	N/A	INTRINSIC
low complexity region	480	503	N/A	INTRINSIC
low complexity region	631	643	N/A	INTRINSIC
low complexity region	1100	1118	N/A	INTRINSIC
low complexity region	1196	1207	N/A	INTRINSIC
low complexity region	1251	1265	N/A	INTRINSIC
low complexity region	1596	1607	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159573

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161036

Predicted Effect

possibly damaging
Transcript: ENSMUST00000162112
AA Change: T180A

PolyPhen 2 Score 0.786 (Sensitivity: 0.85; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000124348
Gene: ENSMUSG00000036523
AA Change: T180A

Domain	Start	End	E-Value	Type
low complexity region	52	71	N/A	INTRINSIC
low complexity region	292	303	N/A	INTRINSIC
low complexity region	437	453	N/A	INTRINSIC
low complexity region	480	503	N/A	INTRINSIC
low complexity region	631	643	N/A	INTRINSIC
low complexity region	1128	1146	N/A	INTRINSIC
low complexity region	1224	1235	N/A	INTRINSIC
low complexity region	1279	1293	N/A	INTRINSIC
low complexity region	1624	1635	N/A	INTRINSIC

Meta Mutation Damage Score

0.0612

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.6%
20x: 93.5%

Validation Efficiency

100% (91/91)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 80 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Afg2a	T	A	3: 37,433,277 (GRCm38)		probably benign	Het
Aim2	T	C	1: 173,455,366 (GRCm38)	Y5H	probably damaging	Het
Atosa	G	A	9: 75,008,889 (GRCm38)	E257K	probably damaging	Het
Atp7b	A	G	8: 22,027,698 (GRCm38)	S375P	possibly damaging	Het
BC106179	C	A	16: 23,224,442 (GRCm38)		probably benign	Het
Brinp3	T	A	1: 146,901,049 (GRCm38)	N411K	probably benign	Het
Cacna1d	A	G	14: 30,079,332 (GRCm38)	V1386A	probably damaging	Het
Cuzd1	T	A	7: 131,311,523 (GRCm38)	Y455F	probably damaging	Het
Dctd	C	T	8: 48,137,414 (GRCm38)		probably benign	Het
Dip2b	T	A	15: 100,195,784 (GRCm38)		probably null	Het
Dot1l	G	T	10: 80,771,196 (GRCm38)	R108L	probably benign	Het
Dysf	T	C	6: 84,151,986 (GRCm38)	S1413P	probably damaging	Het
Eea1	C	A	10: 96,011,021 (GRCm38)	R388S	probably benign	Het
Elavl1	C	T	8: 4,301,723 (GRCm38)	R131Q	probably benign	Het
Erich6b	A	G	14: 75,665,156 (GRCm38)	T138A	possibly damaging	Het
Esr1	C	T	10: 4,712,394 (GRCm38)	T4I	probably damaging	Het
Ets1	T	C	9: 32,732,999 (GRCm38)	S152P	possibly damaging	Het
Fcsk	C	T	8: 110,887,830 (GRCm38)	C609Y	probably damaging	Het
Flrt2	T	C	12: 95,779,773 (GRCm38)	V295A	probably damaging	Het
Gm13196	A	G	2: 4,700,338 (GRCm38)		noncoding transcript	Het
Gm5965	T	A	16: 88,778,424 (GRCm38)	Y162N	probably benign	Het
Gm7853	A	T	14: 36,089,509 (GRCm38)		noncoding transcript	Het
Gm8126	C	T	14: 43,261,608 (GRCm38)	A178V	probably benign	Het
Gpihbp1	A	T	15: 75,597,721 (GRCm38)		probably benign	Het
Gsdme	C	T	6: 50,246,012 (GRCm38)	V108M	possibly damaging	Het
Gtpbp4	T	C	13: 8,989,066 (GRCm38)	Y157C	probably benign	Het
Gvin3	A	G	7: 106,601,560 (GRCm38)		noncoding transcript	Het
Hivep1	T	A	13: 42,158,753 (GRCm38)	F1490I	probably benign	Het
Il17ra	T	C	6: 120,482,207 (GRCm38)	V773A	probably benign	Het
Kctd8	T	A	5: 69,110,733 (GRCm38)	T345S	probably benign	Het
Kdm3b	T	C	18: 34,824,710 (GRCm38)	S1243P	probably benign	Het
Klhdc1	T	C	12: 69,251,938 (GRCm38)	V99A	possibly damaging	Het
Lars1	T	G	18: 42,221,547 (GRCm38)	E778D	probably benign	Het
Map7	C	T	10: 20,261,918 (GRCm38)	R279*	probably null	Het
Mdp1	C	T	14: 55,659,226 (GRCm38)	R126Q	probably damaging	Het
Mtbp	A	G	15: 55,603,187 (GRCm38)	D532G	probably benign	Het
Mylk	G	A	16: 34,899,507 (GRCm38)	V597I	probably benign	Het
Necab1	A	G	4: 14,947,503 (GRCm38)		probably benign	Het
Nisch	C	T	14: 31,187,229 (GRCm38)		probably benign	Het
Nlrp1a	T	C	11: 71,122,705 (GRCm38)	D573G	probably benign	Het
Noct	C	A	3: 51,248,061 (GRCm38)	N83K	probably damaging	Het
Or10am5	A	G	7: 6,514,547 (GRCm38)	L294P	probably damaging	Het
Or1b1	C	T	2: 37,105,455 (GRCm38)	R65H	possibly damaging	Het
Or2a12	C	A	6: 42,927,433 (GRCm38)	D67E	probably damaging	Het
Or2ad1	T	C	13: 21,142,265 (GRCm38)	N264S	probably benign	Het
Or52n4b	A	G	7: 108,544,848 (GRCm38)	I106V	probably benign	Het
Or6b13	C	T	7: 140,201,838 (GRCm38)	A311T	probably benign	Het
Or6c201	T	C	10: 129,133,615 (GRCm38)	H51R	probably benign	Het
Osgepl1	T	A	1: 53,318,180 (GRCm38)	V167D	probably damaging	Het
Pabpc6	T	C	17: 9,668,560 (GRCm38)	E354G	probably damaging	Het
Pgghg	A	C	7: 140,943,390 (GRCm38)	D194A	probably benign	Het
Podnl1	A	T	8: 84,126,258 (GRCm38)	H19L	probably benign	Het
Pold1	G	T	7: 44,533,902 (GRCm38)	A977E	probably benign	Het
Poldip3	T	C	15: 83,133,194 (GRCm38)	T227A	probably damaging	Het
Prss43	A	G	9: 110,827,421 (GRCm38)	S59G	possibly damaging	Het
Ptpn14	T	A	1: 189,850,534 (GRCm38)	I526N	probably benign	Het
Ptprb	T	C	10: 116,348,127 (GRCm38)	S1615P	possibly damaging	Het
Ptpro	A	G	6: 137,377,132 (GRCm38)	K169E	probably damaging	Het
Rab15	T	C	12: 76,800,567 (GRCm38)	E114G	probably damaging	Het
Rcvrn	A	G	11: 67,695,724 (GRCm38)	E103G	probably benign	Het
Repin1	T	A	6: 48,594,845 (GRCm38)		probably benign	Het
Rita1	T	A	5: 120,611,383 (GRCm38)	K88N	probably damaging	Het
Rtkn2	T	C	10: 68,041,409 (GRCm38)	V433A	probably benign	Het
Runx1t1	T	C	4: 13,865,231 (GRCm38)	I314T	possibly damaging	Het
Serpinb9c	A	C	13: 33,154,431 (GRCm38)	S190A	probably benign	Het
Shank2	C	A	7: 144,070,179 (GRCm38)	H300Q	probably benign	Het
Slc4a4	A	G	5: 89,149,298 (GRCm38)		probably null	Het
Slc5a8	T	C	10: 88,909,654 (GRCm38)	S375P	probably benign	Het
Spns3	C	A	11: 72,537,201 (GRCm38)	W251L	probably damaging	Het
Spta1	A	G	1: 174,240,223 (GRCm38)	N2072S	possibly damaging	Het
Sptbn1	A	G	11: 30,124,016 (GRCm38)	V1351A	probably benign	Het
Sytl2	A	T	7: 90,381,315 (GRCm38)		probably benign	Het
Tax1bp1	A	G	6: 52,729,493 (GRCm38)		probably benign	Het
Tg	A	G	15: 66,696,586 (GRCm38)	D1374G	probably benign	Het
Tlr1	A	G	5: 64,926,224 (GRCm38)	S337P	probably damaging	Het
Trp63	A	T	16: 25,868,227 (GRCm38)	D303V	probably damaging	Het
Ttn	G	A	2: 76,852,906 (GRCm38)		probably benign	Het
Txndc5	T	C	13: 38,528,184 (GRCm38)		probably null	Het
Vmn2r77	T	G	7: 86,801,807 (GRCm38)	D300E	possibly damaging	Het
Zfp729a	A	T	13: 67,620,246 (GRCm38)	N621K	probably benign	Het

Other mutations in Greb1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00155:Greb1	APN	12	16,711,961 (GRCm38)	missense	probably damaging	1.00
IGL01316:Greb1	APN	12	16,698,586 (GRCm38)	missense	probably benign	0.04
IGL01464:Greb1	APN	12	16,714,826 (GRCm38)	missense	probably damaging	0.99
IGL01474:Greb1	APN	12	16,684,501 (GRCm38)	missense	probably benign
IGL01522:Greb1	APN	12	16,701,201 (GRCm38)	missense	probably damaging	1.00
IGL01824:Greb1	APN	12	16,711,716 (GRCm38)	nonsense	probably null
IGL01837:Greb1	APN	12	16,684,451 (GRCm38)	missense	probably benign	0.19
IGL01991:Greb1	APN	12	16,699,681 (GRCm38)	missense	probably damaging	1.00
IGL01996:Greb1	APN	12	16,690,845 (GRCm38)	missense	possibly damaging	0.70
IGL02213:Greb1	APN	12	16,706,232 (GRCm38)	missense	probably damaging	1.00
IGL02267:Greb1	APN	12	16,717,208 (GRCm38)	missense	probably benign	0.00
IGL02512:Greb1	APN	12	16,692,712 (GRCm38)	missense	possibly damaging	0.79
IGL02583:Greb1	APN	12	16,706,295 (GRCm38)	splice site	probably benign
IGL02613:Greb1	APN	12	16,739,888 (GRCm38)	critical splice donor site	probably null
IGL02648:Greb1	APN	12	16,708,682 (GRCm38)	missense	probably damaging	1.00
IGL02679:Greb1	APN	12	16,708,723 (GRCm38)	missense	probably damaging	1.00
begraben	UTSW	12	16,684,373 (GRCm38)	missense	possibly damaging	0.51
Eared	UTSW	12	16,673,863 (GRCm38)	missense	probably damaging	1.00
Humpback	UTSW	12	16,701,171 (GRCm38)	missense	probably damaging	1.00
pied_billed	UTSW	12	16,724,857 (GRCm38)	missense	possibly damaging	0.79
rednecked	UTSW	12	16,682,152 (GRCm38)	missense	probably damaging	0.99
G1patch:Greb1	UTSW	12	16,688,567 (GRCm38)	missense	probably damaging	1.00
IGL03048:Greb1	UTSW	12	16,733,331 (GRCm38)	missense	probably damaging	1.00
R0083:Greb1	UTSW	12	16,696,451 (GRCm38)	missense	probably benign
R0100:Greb1	UTSW	12	16,680,224 (GRCm38)	missense	probably benign	0.41
R0100:Greb1	UTSW	12	16,680,224 (GRCm38)	missense	probably benign	0.41
R0220:Greb1	UTSW	12	16,682,286 (GRCm38)	missense	probably damaging	1.00
R0245:Greb1	UTSW	12	16,696,456 (GRCm38)	missense	probably damaging	1.00
R0540:Greb1	UTSW	12	16,682,193 (GRCm38)	missense	probably damaging	1.00
R0547:Greb1	UTSW	12	16,723,411 (GRCm38)	missense	probably benign
R0563:Greb1	UTSW	12	16,680,267 (GRCm38)	missense	probably benign	0.23
R0607:Greb1	UTSW	12	16,682,193 (GRCm38)	missense	probably damaging	1.00
R0610:Greb1	UTSW	12	16,696,442 (GRCm38)	missense	probably benign
R0652:Greb1	UTSW	12	16,696,456 (GRCm38)	missense	probably damaging	1.00
R0659:Greb1	UTSW	12	16,680,212 (GRCm38)	missense	probably damaging	0.99
R0945:Greb1	UTSW	12	16,673,802 (GRCm38)	missense	probably benign	0.31
R1055:Greb1	UTSW	12	16,682,251 (GRCm38)	missense	probably damaging	0.98
R1445:Greb1	UTSW	12	16,707,851 (GRCm38)	missense	probably damaging	1.00
R1471:Greb1	UTSW	12	16,711,774 (GRCm38)	missense	probably damaging	0.97
R1503:Greb1	UTSW	12	16,724,819 (GRCm38)	nonsense	probably null
R1566:Greb1	UTSW	12	16,711,828 (GRCm38)	missense	possibly damaging	0.94
R1614:Greb1	UTSW	12	16,701,171 (GRCm38)	missense	probably damaging	1.00
R1623:Greb1	UTSW	12	16,674,770 (GRCm38)	missense	probably damaging	1.00
R1751:Greb1	UTSW	12	16,723,438 (GRCm38)	splice site	probably benign
R1778:Greb1	UTSW	12	16,690,894 (GRCm38)	missense	probably benign
R1842:Greb1	UTSW	12	16,696,243 (GRCm38)	missense	probably damaging	1.00
R2040:Greb1	UTSW	12	16,702,650 (GRCm38)	missense	probably damaging	1.00
R2153:Greb1	UTSW	12	16,699,532 (GRCm38)	missense	probably damaging	1.00
R2178:Greb1	UTSW	12	16,696,387 (GRCm38)	missense	probably damaging	1.00
R2194:Greb1	UTSW	12	16,690,908 (GRCm38)	missense	probably benign	0.08
R2248:Greb1	UTSW	12	16,680,378 (GRCm38)	missense	possibly damaging	0.90
R2474:Greb1	UTSW	12	16,714,953 (GRCm38)	missense	possibly damaging	0.93
R2509:Greb1	UTSW	12	16,724,922 (GRCm38)	missense	probably damaging	1.00
R2860:Greb1	UTSW	12	16,711,745 (GRCm38)	missense	probably benign	0.28
R2861:Greb1	UTSW	12	16,711,745 (GRCm38)	missense	probably benign	0.28
R2862:Greb1	UTSW	12	16,711,745 (GRCm38)	missense	probably benign	0.28
R2866:Greb1	UTSW	12	16,699,550 (GRCm38)	missense	probably damaging	1.00
R2890:Greb1	UTSW	12	16,704,478 (GRCm38)	missense	probably damaging	1.00
R3056:Greb1	UTSW	12	16,688,591 (GRCm38)	missense	probably damaging	0.96
R3863:Greb1	UTSW	12	16,702,420 (GRCm38)	missense	probably damaging	1.00
R3864:Greb1	UTSW	12	16,702,420 (GRCm38)	missense	probably damaging	1.00
R3956:Greb1	UTSW	12	16,682,299 (GRCm38)	missense	probably damaging	1.00
R4493:Greb1	UTSW	12	16,698,610 (GRCm38)	missense	probably benign	0.14
R4548:Greb1	UTSW	12	16,699,675 (GRCm38)	missense	probably damaging	1.00
R4683:Greb1	UTSW	12	16,711,773 (GRCm38)	missense	possibly damaging	0.75
R4739:Greb1	UTSW	12	16,696,328 (GRCm38)	missense	probably damaging	1.00
R4770:Greb1	UTSW	12	16,681,356 (GRCm38)	missense	probably benign	0.03
R4838:Greb1	UTSW	12	16,684,360 (GRCm38)	critical splice donor site	probably null
R4925:Greb1	UTSW	12	16,681,471 (GRCm38)	missense	probably damaging	1.00
R4982:Greb1	UTSW	12	16,724,761 (GRCm38)	missense	probably damaging	0.98
R5086:Greb1	UTSW	12	16,708,022 (GRCm38)	intron	probably benign
R5213:Greb1	UTSW	12	16,714,790 (GRCm38)	nonsense	probably null
R5310:Greb1	UTSW	12	16,716,759 (GRCm38)	missense	probably benign	0.09
R5353:Greb1	UTSW	12	16,688,566 (GRCm38)	nonsense	probably null
R5544:Greb1	UTSW	12	16,673,796 (GRCm38)	missense	probably damaging	1.00
R5605:Greb1	UTSW	12	16,708,726 (GRCm38)	missense	probably damaging	0.96
R5708:Greb1	UTSW	12	16,673,842 (GRCm38)	missense	probably benign	0.11
R5837:Greb1	UTSW	12	16,688,585 (GRCm38)	missense	probably damaging	1.00
R5890:Greb1	UTSW	12	16,733,421 (GRCm38)	missense	possibly damaging	0.90
R5938:Greb1	UTSW	12	16,717,258 (GRCm38)	missense	probably damaging	1.00
R6049:Greb1	UTSW	12	16,681,394 (GRCm38)	missense	probably damaging	0.99
R6093:Greb1	UTSW	12	16,684,486 (GRCm38)	missense	probably benign
R6120:Greb1	UTSW	12	16,708,621 (GRCm38)	missense	probably damaging	0.99
R6175:Greb1	UTSW	12	16,674,770 (GRCm38)	missense	probably damaging	1.00
R6247:Greb1	UTSW	12	16,716,675 (GRCm38)	missense	probably damaging	1.00
R6274:Greb1	UTSW	12	16,735,151 (GRCm38)	missense	probably damaging	0.97
R6376:Greb1	UTSW	12	16,699,579 (GRCm38)	missense	probably damaging	0.97
R6523:Greb1	UTSW	12	16,684,373 (GRCm38)	missense	possibly damaging	0.51
R6557:Greb1	UTSW	12	16,710,383 (GRCm38)	missense	probably benign	0.00
R6602:Greb1	UTSW	12	16,709,440 (GRCm38)	missense	probably benign	0.44
R6621:Greb1	UTSW	12	16,692,717 (GRCm38)	missense	probably damaging	1.00
R6645:Greb1	UTSW	12	16,698,579 (GRCm38)	missense	probably benign	0.07
R6725:Greb1	UTSW	12	16,688,567 (GRCm38)	missense	probably damaging	1.00
R6750:Greb1	UTSW	12	16,688,583 (GRCm38)	missense	probably benign	0.05
R6863:Greb1	UTSW	12	16,684,420 (GRCm38)	missense	probably damaging	1.00
R6914:Greb1	UTSW	12	16,707,902 (GRCm38)	missense	probably damaging	0.97
R6996:Greb1	UTSW	12	16,723,354 (GRCm38)	missense	probably benign	0.00
R7083:Greb1	UTSW	12	16,723,314 (GRCm38)	missense	probably benign
R7147:Greb1	UTSW	12	16,733,427 (GRCm38)	missense	probably damaging	1.00
R7238:Greb1	UTSW	12	16,674,672 (GRCm38)	missense	probably damaging	0.99
R7290:Greb1	UTSW	12	16,711,738 (GRCm38)	missense	probably damaging	1.00
R7358:Greb1	UTSW	12	16,724,881 (GRCm38)	missense	probably damaging	1.00
R7395:Greb1	UTSW	12	16,709,430 (GRCm38)	critical splice donor site	probably null
R7526:Greb1	UTSW	12	16,716,765 (GRCm38)	missense	probably benign	0.00
R7530:Greb1	UTSW	12	16,717,206 (GRCm38)	missense	probably benign	0.02
R7536:Greb1	UTSW	12	16,682,185 (GRCm38)	missense	probably damaging	1.00
R7643:Greb1	UTSW	12	16,711,996 (GRCm38)	missense	probably damaging	0.99
R7732:Greb1	UTSW	12	16,673,863 (GRCm38)	missense	probably damaging	1.00
R7740:Greb1	UTSW	12	16,740,121 (GRCm38)	start gained	probably benign
R7747:Greb1	UTSW	12	16,674,795 (GRCm38)	missense	probably benign	0.01
R7760:Greb1	UTSW	12	16,723,416 (GRCm38)	missense	probably benign
R7937:Greb1	UTSW	12	16,716,669 (GRCm38)	missense	probably damaging	0.99
R8043:Greb1	UTSW	12	16,711,789 (GRCm38)	missense	probably damaging	1.00
R8259:Greb1	UTSW	12	16,724,924 (GRCm38)	nonsense	probably null
R8553:Greb1	UTSW	12	16,723,327 (GRCm38)	missense	probably benign	0.00
R8559:Greb1	UTSW	12	16,696,435 (GRCm38)	missense	probably damaging	1.00
R8690:Greb1	UTSW	12	16,696,547 (GRCm38)	missense	probably benign	0.03
R8830:Greb1	UTSW	12	16,688,519 (GRCm38)	missense	probably benign	0.35
R8911:Greb1	UTSW	12	16,690,902 (GRCm38)	missense	possibly damaging	0.84
R8963:Greb1	UTSW	12	16,724,884 (GRCm38)	missense	probably damaging	1.00
R8986:Greb1	UTSW	12	16,684,456 (GRCm38)	missense	probably damaging	0.99
R9013:Greb1	UTSW	12	16,739,969 (GRCm38)	missense	probably damaging	1.00
R9279:Greb1	UTSW	12	16,682,152 (GRCm38)	missense	probably damaging	0.99
R9360:Greb1	UTSW	12	16,740,036 (GRCm38)	missense	probably damaging	1.00
R9563:Greb1	UTSW	12	16,724,823 (GRCm38)	missense	probably benign	0.06
R9616:Greb1	UTSW	12	16,740,037 (GRCm38)	missense	probably damaging	1.00
R9627:Greb1	UTSW	12	16,706,166 (GRCm38)	missense	probably damaging	1.00
R9731:Greb1	UTSW	12	16,688,597 (GRCm38)	missense	probably damaging	1.00
R9761:Greb1	UTSW	12	16,701,274 (GRCm38)	missense	probably benign	0.05
Z1176:Greb1	UTSW	12	16,696,756 (GRCm38)	missense	probably benign	0.00
Z1177:Greb1	UTSW	12	16,702,491 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCTGTACAGAGATCCCACCC -3'
(R):5'- CTGATTACCAGGACAGGTTCTCTG -3'

Sequencing Primer
(F):5'- CTCCTAGCCTCACAATGCC -3'
(R):5'- CTCTGGCACTCTCTGGGTG -3'

Posted On

2016-06-06