Incidental Mutation 'R5011:Tnn'
| ID |
390471 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
tenascin-W, Tnw |
| MMRRC Submission |
042602-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.396)
|
| Stock # |
R5011 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159912599-159981150 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 159953949 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 602
(E602G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039178
AA Change: E602G
PolyPhen 2
Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: E602G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000131919
AA Change: E602G
PolyPhen 2
Score 0.721 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
AA Change: E602G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.5%
|
| Validation Efficiency |
100% (104/104) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810010H24Rik |
T |
C |
11: 106,919,324 (GRCm39) |
V223A |
probably damaging |
Het |
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| Ahctf1 |
A |
T |
1: 179,611,675 (GRCm39) |
I565N |
possibly damaging |
Het |
| Ank1 |
C |
T |
8: 23,572,300 (GRCm39) |
T70I |
probably damaging |
Het |
| Atg16l1 |
C |
A |
1: 87,701,902 (GRCm39) |
S248* |
probably null |
Het |
| Atp13a5 |
A |
T |
16: 29,169,566 (GRCm39) |
L42Q |
probably damaging |
Het |
| Atxn1 |
T |
C |
13: 45,710,545 (GRCm39) |
N796D |
probably damaging |
Het |
| C3 |
T |
A |
17: 57,530,236 (GRCm39) |
Y455F |
probably benign |
Het |
| Card11 |
A |
T |
5: 140,862,275 (GRCm39) |
D1007E |
possibly damaging |
Het |
| Cbr2 |
T |
C |
11: 120,621,697 (GRCm39) |
D60G |
possibly damaging |
Het |
| Cgn |
T |
A |
3: 94,683,455 (GRCm39) |
E400V |
probably null |
Het |
| Chil3 |
T |
A |
3: 106,057,477 (GRCm39) |
Y229F |
possibly damaging |
Het |
| Clcn2 |
G |
A |
16: 20,525,965 (GRCm39) |
P785S |
probably damaging |
Het |
| Clk1 |
T |
C |
1: 58,453,642 (GRCm39) |
I315V |
probably benign |
Het |
| Cops6 |
A |
G |
5: 138,160,459 (GRCm39) |
D102G |
probably benign |
Het |
| Dennd5a |
A |
G |
7: 109,513,983 (GRCm39) |
I743T |
possibly damaging |
Het |
| Dnaaf5 |
T |
A |
5: 139,149,012 (GRCm39) |
L437Q |
probably damaging |
Het |
| Dnah12 |
T |
A |
14: 26,431,326 (GRCm39) |
D381E |
probably benign |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Draxin |
C |
A |
4: 148,192,436 (GRCm39) |
R292L |
probably damaging |
Het |
| Dst |
T |
C |
1: 34,289,728 (GRCm39) |
V5776A |
probably damaging |
Het |
| Eddm13 |
G |
A |
7: 6,269,332 (GRCm39) |
|
probably benign |
Het |
| Ercc4 |
G |
A |
16: 12,941,445 (GRCm39) |
|
probably benign |
Het |
| Eya1 |
T |
A |
1: 14,254,582 (GRCm39) |
N417Y |
probably damaging |
Het |
| Fam149b |
T |
A |
14: 20,413,439 (GRCm39) |
H219Q |
possibly damaging |
Het |
| Fam227b |
G |
A |
2: 125,958,043 (GRCm39) |
P241S |
probably damaging |
Het |
| Fat1 |
A |
T |
8: 45,484,300 (GRCm39) |
|
probably null |
Het |
| Fbxl18 |
A |
G |
5: 142,872,435 (GRCm39) |
S267P |
probably damaging |
Het |
| Fer1l4 |
T |
C |
2: 155,873,135 (GRCm39) |
Y1315C |
probably damaging |
Het |
| Fgd2 |
T |
C |
17: 29,593,954 (GRCm39) |
|
probably null |
Het |
| Gm7251 |
T |
A |
13: 49,958,656 (GRCm39) |
|
noncoding transcript |
Het |
| Golt1a |
T |
C |
1: 133,248,006 (GRCm39) |
V78A |
probably damaging |
Het |
| Gsn |
T |
A |
2: 35,188,933 (GRCm39) |
Y440N |
probably damaging |
Het |
| Gtf2ird2 |
G |
T |
5: 134,245,824 (GRCm39) |
S694I |
possibly damaging |
Het |
| H2-Ob |
T |
A |
17: 34,460,253 (GRCm39) |
|
probably null |
Het |
| Hsp90b1 |
T |
C |
10: 86,532,617 (GRCm39) |
D353G |
probably benign |
Het |
| Ilk |
A |
G |
7: 105,391,456 (GRCm39) |
D374G |
probably damaging |
Het |
| Invs |
G |
A |
4: 48,421,807 (GRCm39) |
R813Q |
probably damaging |
Het |
| Itga7 |
G |
A |
10: 128,785,316 (GRCm39) |
V836M |
possibly damaging |
Het |
| Itln1 |
T |
A |
1: 171,360,958 (GRCm39) |
K45* |
probably null |
Het |
| Ivd |
A |
G |
2: 118,710,946 (GRCm39) |
Y385C |
probably damaging |
Het |
| Ivns1abp |
T |
A |
1: 151,238,953 (GRCm39) |
M589K |
possibly damaging |
Het |
| Jakmip3 |
C |
T |
7: 138,621,951 (GRCm39) |
R284W |
probably damaging |
Het |
| Kank3 |
T |
C |
17: 34,041,044 (GRCm39) |
L512P |
probably damaging |
Het |
| Kcnn2 |
T |
A |
18: 45,818,352 (GRCm39) |
I483N |
possibly damaging |
Het |
| Klk1b4 |
A |
G |
7: 43,860,492 (GRCm39) |
N170S |
probably benign |
Het |
| Klk1b9 |
A |
C |
7: 43,445,419 (GRCm39) |
D203A |
probably damaging |
Het |
| Lbr |
A |
T |
1: 181,647,453 (GRCm39) |
Y199* |
probably null |
Het |
| Lcn6 |
T |
A |
2: 25,567,082 (GRCm39) |
|
probably null |
Het |
| Lrriq1 |
T |
C |
10: 103,025,784 (GRCm39) |
D946G |
probably damaging |
Het |
| Ltbp1 |
T |
A |
17: 75,373,152 (GRCm39) |
L265H |
probably damaging |
Het |
| Maml3 |
A |
T |
3: 51,598,196 (GRCm39) |
N183K |
possibly damaging |
Het |
| Mprip |
T |
C |
11: 59,650,721 (GRCm39) |
V1475A |
possibly damaging |
Het |
| Myh4 |
C |
A |
11: 67,147,189 (GRCm39) |
S1611R |
probably benign |
Het |
| Nagpa |
A |
T |
16: 5,013,743 (GRCm39) |
M365K |
probably benign |
Het |
| Nckap5l |
G |
T |
15: 99,324,457 (GRCm39) |
P682Q |
probably benign |
Het |
| Nudt12 |
T |
C |
17: 59,303,499 (GRCm39) |
|
probably benign |
Het |
| Nup153 |
T |
C |
13: 46,840,879 (GRCm39) |
T910A |
possibly damaging |
Het |
| Or1e31 |
T |
A |
11: 73,690,473 (GRCm39) |
T37S |
possibly damaging |
Het |
| Or5ae2 |
T |
C |
7: 84,505,646 (GRCm39) |
V23A |
probably damaging |
Het |
| Or7c74 |
A |
G |
2: 37,160,937 (GRCm39) |
|
noncoding transcript |
Het |
| Or8k53 |
A |
T |
2: 86,177,647 (GRCm39) |
F154L |
probably benign |
Het |
| Pate14 |
T |
C |
9: 36,549,120 (GRCm39) |
N47D |
probably benign |
Het |
| Pbx2 |
T |
A |
17: 34,813,673 (GRCm39) |
C224* |
probably null |
Het |
| Pcdha6 |
A |
G |
18: 37,100,960 (GRCm39) |
D51G |
probably damaging |
Het |
| Pnpla1 |
C |
T |
17: 29,104,558 (GRCm39) |
T538I |
possibly damaging |
Het |
| Pnpla2 |
T |
C |
7: 141,039,204 (GRCm39) |
|
probably null |
Het |
| Psme2b |
C |
T |
11: 48,836,654 (GRCm39) |
E98K |
probably benign |
Het |
| Ranbp2 |
T |
A |
10: 58,297,717 (GRCm39) |
S375T |
probably benign |
Het |
| Rimbp2 |
T |
C |
5: 128,880,985 (GRCm39) |
Y134C |
probably damaging |
Het |
| Ryr1 |
G |
A |
7: 28,802,234 (GRCm39) |
|
probably null |
Het |
| Sh3tc1 |
G |
T |
5: 35,857,633 (GRCm39) |
A1185D |
probably damaging |
Het |
| Sin3b |
G |
A |
8: 73,471,184 (GRCm39) |
S377N |
probably benign |
Het |
| Slc28a2 |
T |
C |
2: 122,288,371 (GRCm39) |
M554T |
possibly damaging |
Het |
| Snhg11 |
T |
C |
2: 158,218,872 (GRCm39) |
|
probably benign |
Het |
| Spink5 |
A |
T |
18: 44,139,479 (GRCm39) |
N614I |
probably damaging |
Het |
| Tert |
T |
C |
13: 73,794,428 (GRCm39) |
|
probably null |
Het |
| Thap4 |
T |
C |
1: 93,677,598 (GRCm39) |
Y396C |
probably damaging |
Het |
| Tle2 |
T |
C |
10: 81,420,531 (GRCm39) |
L348P |
probably damaging |
Het |
| Tmem104 |
T |
C |
11: 115,134,312 (GRCm39) |
S283P |
probably damaging |
Het |
| Tpm4 |
A |
G |
8: 72,900,938 (GRCm39) |
K190R |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,870,485 (GRCm39) |
E196G |
probably benign |
Het |
| Ugt3a1 |
T |
C |
15: 9,365,373 (GRCm39) |
W329R |
probably damaging |
Het |
| Unc13a |
G |
A |
8: 72,094,121 (GRCm39) |
Q1327* |
probably null |
Het |
| Vmn1r194 |
C |
T |
13: 22,429,058 (GRCm39) |
T225I |
probably benign |
Het |
| Vmn1r215 |
T |
C |
13: 23,260,721 (GRCm39) |
S254P |
probably damaging |
Het |
| Vmn2r109 |
T |
C |
17: 20,775,451 (GRCm39) |
E92G |
probably damaging |
Het |
| Ythdc2 |
A |
G |
18: 44,987,809 (GRCm39) |
M625V |
probably benign |
Het |
| Zfp106 |
A |
G |
2: 120,341,015 (GRCm39) |
W1832R |
probably damaging |
Het |
| Zfp189 |
G |
A |
4: 49,530,438 (GRCm39) |
G514S |
probably damaging |
Het |
| Zfp768 |
T |
C |
7: 126,942,875 (GRCm39) |
R418G |
probably damaging |
Het |
| Zmynd11 |
C |
T |
13: 9,739,479 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
159,953,021 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
159,925,776 (GRCm39) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
159,915,962 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
159,975,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
159,948,124 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
159,953,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
159,975,172 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
159,934,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
159,916,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
159,972,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
159,968,163 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
159,950,222 (GRCm39) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
159,942,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
159,913,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
159,968,347 (GRCm39) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
159,943,848 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
159,953,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
159,924,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
159,913,647 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
159,932,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
159,948,137 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
159,948,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
159,943,907 (GRCm39) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
159,952,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
159,952,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
159,924,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
159,945,978 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
159,975,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Tnn
|
UTSW |
1 |
159,972,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
159,975,154 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
159,968,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
159,943,752 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
159,924,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
159,968,170 (GRCm39) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
159,924,798 (GRCm39) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
159,938,079 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
159,966,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
159,934,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
159,973,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
159,924,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
159,972,681 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4701:Tnn
|
UTSW |
1 |
159,975,338 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4703:Tnn
|
UTSW |
1 |
159,943,815 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4737:Tnn
|
UTSW |
1 |
159,973,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4868:Tnn
|
UTSW |
1 |
159,958,443 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4977:Tnn
|
UTSW |
1 |
159,948,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5026:Tnn
|
UTSW |
1 |
159,973,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Tnn
|
UTSW |
1 |
159,972,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5049:Tnn
|
UTSW |
1 |
159,968,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
159,948,122 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
159,950,464 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
159,972,569 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
159,975,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
159,950,272 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
159,937,831 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
159,948,106 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
159,937,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
159,925,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
159,913,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
159,973,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
159,972,774 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
159,942,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
159,915,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
159,942,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
159,948,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
159,932,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
159,953,947 (GRCm39) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
159,934,687 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7340:Tnn
|
UTSW |
1 |
159,973,592 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7472:Tnn
|
UTSW |
1 |
159,937,917 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
159,937,929 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
159,946,074 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
159,915,984 (GRCm39) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
159,942,255 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
159,950,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
159,934,630 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
159,953,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
159,958,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
159,924,790 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
159,950,397 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
159,973,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
159,937,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
159,943,846 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
159,937,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
159,953,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
159,953,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
159,913,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
159,973,863 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
159,954,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCACCGAGTCTGCTAAAAG -3'
(R):5'- GTGACAGAGAACAGCCTCTC -3'
Sequencing Primer
(F):5'- ACTTAGATTGTGCCGCAAGC -3'
(R):5'- TCTCTGTCTCGTGGGACCCAG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation