Incidental Mutation 'R5011:Lrriq1'
| ID |
390519 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrriq1
|
| Ensembl Gene |
ENSMUSG00000019892 |
| Gene Name |
leucine-rich repeats and IQ motif containing 1 |
| Synonyms |
Gm1557, LOC380658, 4930503E15Rik |
| MMRRC Submission |
042602-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.073)
|
| Stock # |
R5011 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
102881892-103072183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103025784 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 946
(D946G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131419
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166240]
|
| AlphaFold |
Q0P5X1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166240
AA Change: D946G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131419
Gene: ENSMUSG00000019892
AA Change: D946G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
IQ
|
290 |
312 |
9.78e1 |
SMART |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
LRR
|
873 |
894 |
2.14e1 |
SMART |
|
LRR
|
895 |
917 |
4.45e1 |
SMART |
|
LRR
|
984 |
1005 |
2.03e2 |
SMART |
|
LRR
|
1029 |
1052 |
3.65e0 |
SMART |
|
low complexity region
|
1244 |
1258 |
N/A |
INTRINSIC |
|
IQ
|
1279 |
1301 |
5.61e1 |
SMART |
|
IQ
|
1339 |
1361 |
6.7e-3 |
SMART |
|
low complexity region
|
1369 |
1394 |
N/A |
INTRINSIC |
|
low complexity region
|
1502 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1528 |
1543 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1677 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.5%
|
| Validation Efficiency |
100% (104/104) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810010H24Rik |
T |
C |
11: 106,919,324 (GRCm39) |
V223A |
probably damaging |
Het |
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| Ahctf1 |
A |
T |
1: 179,611,675 (GRCm39) |
I565N |
possibly damaging |
Het |
| Ank1 |
C |
T |
8: 23,572,300 (GRCm39) |
T70I |
probably damaging |
Het |
| Atg16l1 |
C |
A |
1: 87,701,902 (GRCm39) |
S248* |
probably null |
Het |
| Atp13a5 |
A |
T |
16: 29,169,566 (GRCm39) |
L42Q |
probably damaging |
Het |
| Atxn1 |
T |
C |
13: 45,710,545 (GRCm39) |
N796D |
probably damaging |
Het |
| C3 |
T |
A |
17: 57,530,236 (GRCm39) |
Y455F |
probably benign |
Het |
| Card11 |
A |
T |
5: 140,862,275 (GRCm39) |
D1007E |
possibly damaging |
Het |
| Cbr2 |
T |
C |
11: 120,621,697 (GRCm39) |
D60G |
possibly damaging |
Het |
| Cgn |
T |
A |
3: 94,683,455 (GRCm39) |
E400V |
probably null |
Het |
| Chil3 |
T |
A |
3: 106,057,477 (GRCm39) |
Y229F |
possibly damaging |
Het |
| Clcn2 |
G |
A |
16: 20,525,965 (GRCm39) |
P785S |
probably damaging |
Het |
| Clk1 |
T |
C |
1: 58,453,642 (GRCm39) |
I315V |
probably benign |
Het |
| Cops6 |
A |
G |
5: 138,160,459 (GRCm39) |
D102G |
probably benign |
Het |
| Dennd5a |
A |
G |
7: 109,513,983 (GRCm39) |
I743T |
possibly damaging |
Het |
| Dnaaf5 |
T |
A |
5: 139,149,012 (GRCm39) |
L437Q |
probably damaging |
Het |
| Dnah12 |
T |
A |
14: 26,431,326 (GRCm39) |
D381E |
probably benign |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Draxin |
C |
A |
4: 148,192,436 (GRCm39) |
R292L |
probably damaging |
Het |
| Dst |
T |
C |
1: 34,289,728 (GRCm39) |
V5776A |
probably damaging |
Het |
| Eddm13 |
G |
A |
7: 6,269,332 (GRCm39) |
|
probably benign |
Het |
| Ercc4 |
G |
A |
16: 12,941,445 (GRCm39) |
|
probably benign |
Het |
| Eya1 |
T |
A |
1: 14,254,582 (GRCm39) |
N417Y |
probably damaging |
Het |
| Fam149b |
T |
A |
14: 20,413,439 (GRCm39) |
H219Q |
possibly damaging |
Het |
| Fam227b |
G |
A |
2: 125,958,043 (GRCm39) |
P241S |
probably damaging |
Het |
| Fat1 |
A |
T |
8: 45,484,300 (GRCm39) |
|
probably null |
Het |
| Fbxl18 |
A |
G |
5: 142,872,435 (GRCm39) |
S267P |
probably damaging |
Het |
| Fer1l4 |
T |
C |
2: 155,873,135 (GRCm39) |
Y1315C |
probably damaging |
Het |
| Fgd2 |
T |
C |
17: 29,593,954 (GRCm39) |
|
probably null |
Het |
| Gm7251 |
T |
A |
13: 49,958,656 (GRCm39) |
|
noncoding transcript |
Het |
| Golt1a |
T |
C |
1: 133,248,006 (GRCm39) |
V78A |
probably damaging |
Het |
| Gsn |
T |
A |
2: 35,188,933 (GRCm39) |
Y440N |
probably damaging |
Het |
| Gtf2ird2 |
G |
T |
5: 134,245,824 (GRCm39) |
S694I |
possibly damaging |
Het |
| H2-Ob |
T |
A |
17: 34,460,253 (GRCm39) |
|
probably null |
Het |
| Hsp90b1 |
T |
C |
10: 86,532,617 (GRCm39) |
D353G |
probably benign |
Het |
| Ilk |
A |
G |
7: 105,391,456 (GRCm39) |
D374G |
probably damaging |
Het |
| Invs |
G |
A |
4: 48,421,807 (GRCm39) |
R813Q |
probably damaging |
Het |
| Itga7 |
G |
A |
10: 128,785,316 (GRCm39) |
V836M |
possibly damaging |
Het |
| Itln1 |
T |
A |
1: 171,360,958 (GRCm39) |
K45* |
probably null |
Het |
| Ivd |
A |
G |
2: 118,710,946 (GRCm39) |
Y385C |
probably damaging |
Het |
| Ivns1abp |
T |
A |
1: 151,238,953 (GRCm39) |
M589K |
possibly damaging |
Het |
| Jakmip3 |
C |
T |
7: 138,621,951 (GRCm39) |
R284W |
probably damaging |
Het |
| Kank3 |
T |
C |
17: 34,041,044 (GRCm39) |
L512P |
probably damaging |
Het |
| Kcnn2 |
T |
A |
18: 45,818,352 (GRCm39) |
I483N |
possibly damaging |
Het |
| Klk1b4 |
A |
G |
7: 43,860,492 (GRCm39) |
N170S |
probably benign |
Het |
| Klk1b9 |
A |
C |
7: 43,445,419 (GRCm39) |
D203A |
probably damaging |
Het |
| Lbr |
A |
T |
1: 181,647,453 (GRCm39) |
Y199* |
probably null |
Het |
| Lcn6 |
T |
A |
2: 25,567,082 (GRCm39) |
|
probably null |
Het |
| Ltbp1 |
T |
A |
17: 75,373,152 (GRCm39) |
L265H |
probably damaging |
Het |
| Maml3 |
A |
T |
3: 51,598,196 (GRCm39) |
N183K |
possibly damaging |
Het |
| Mprip |
T |
C |
11: 59,650,721 (GRCm39) |
V1475A |
possibly damaging |
Het |
| Myh4 |
C |
A |
11: 67,147,189 (GRCm39) |
S1611R |
probably benign |
Het |
| Nagpa |
A |
T |
16: 5,013,743 (GRCm39) |
M365K |
probably benign |
Het |
| Nckap5l |
G |
T |
15: 99,324,457 (GRCm39) |
P682Q |
probably benign |
Het |
| Nudt12 |
T |
C |
17: 59,303,499 (GRCm39) |
|
probably benign |
Het |
| Nup153 |
T |
C |
13: 46,840,879 (GRCm39) |
T910A |
possibly damaging |
Het |
| Or1e31 |
T |
A |
11: 73,690,473 (GRCm39) |
T37S |
possibly damaging |
Het |
| Or5ae2 |
T |
C |
7: 84,505,646 (GRCm39) |
V23A |
probably damaging |
Het |
| Or7c74 |
A |
G |
2: 37,160,937 (GRCm39) |
|
noncoding transcript |
Het |
| Or8k53 |
A |
T |
2: 86,177,647 (GRCm39) |
F154L |
probably benign |
Het |
| Pate14 |
T |
C |
9: 36,549,120 (GRCm39) |
N47D |
probably benign |
Het |
| Pbx2 |
T |
A |
17: 34,813,673 (GRCm39) |
C224* |
probably null |
Het |
| Pcdha6 |
A |
G |
18: 37,100,960 (GRCm39) |
D51G |
probably damaging |
Het |
| Pnpla1 |
C |
T |
17: 29,104,558 (GRCm39) |
T538I |
possibly damaging |
Het |
| Pnpla2 |
T |
C |
7: 141,039,204 (GRCm39) |
|
probably null |
Het |
| Psme2b |
C |
T |
11: 48,836,654 (GRCm39) |
E98K |
probably benign |
Het |
| Ranbp2 |
T |
A |
10: 58,297,717 (GRCm39) |
S375T |
probably benign |
Het |
| Rimbp2 |
T |
C |
5: 128,880,985 (GRCm39) |
Y134C |
probably damaging |
Het |
| Ryr1 |
G |
A |
7: 28,802,234 (GRCm39) |
|
probably null |
Het |
| Sh3tc1 |
G |
T |
5: 35,857,633 (GRCm39) |
A1185D |
probably damaging |
Het |
| Sin3b |
G |
A |
8: 73,471,184 (GRCm39) |
S377N |
probably benign |
Het |
| Slc28a2 |
T |
C |
2: 122,288,371 (GRCm39) |
M554T |
possibly damaging |
Het |
| Snhg11 |
T |
C |
2: 158,218,872 (GRCm39) |
|
probably benign |
Het |
| Spink5 |
A |
T |
18: 44,139,479 (GRCm39) |
N614I |
probably damaging |
Het |
| Tert |
T |
C |
13: 73,794,428 (GRCm39) |
|
probably null |
Het |
| Thap4 |
T |
C |
1: 93,677,598 (GRCm39) |
Y396C |
probably damaging |
Het |
| Tle2 |
T |
C |
10: 81,420,531 (GRCm39) |
L348P |
probably damaging |
Het |
| Tmem104 |
T |
C |
11: 115,134,312 (GRCm39) |
S283P |
probably damaging |
Het |
| Tnn |
T |
C |
1: 159,953,949 (GRCm39) |
E602G |
possibly damaging |
Het |
| Tpm4 |
A |
G |
8: 72,900,938 (GRCm39) |
K190R |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,870,485 (GRCm39) |
E196G |
probably benign |
Het |
| Ugt3a1 |
T |
C |
15: 9,365,373 (GRCm39) |
W329R |
probably damaging |
Het |
| Unc13a |
G |
A |
8: 72,094,121 (GRCm39) |
Q1327* |
probably null |
Het |
| Vmn1r194 |
C |
T |
13: 22,429,058 (GRCm39) |
T225I |
probably benign |
Het |
| Vmn1r215 |
T |
C |
13: 23,260,721 (GRCm39) |
S254P |
probably damaging |
Het |
| Vmn2r109 |
T |
C |
17: 20,775,451 (GRCm39) |
E92G |
probably damaging |
Het |
| Ythdc2 |
A |
G |
18: 44,987,809 (GRCm39) |
M625V |
probably benign |
Het |
| Zfp106 |
A |
G |
2: 120,341,015 (GRCm39) |
W1832R |
probably damaging |
Het |
| Zfp189 |
G |
A |
4: 49,530,438 (GRCm39) |
G514S |
probably damaging |
Het |
| Zfp768 |
T |
C |
7: 126,942,875 (GRCm39) |
R418G |
probably damaging |
Het |
| Zmynd11 |
C |
T |
13: 9,739,479 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Lrriq1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00988:Lrriq1
|
APN |
10 |
102,997,757 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01523:Lrriq1
|
APN |
10 |
103,053,977 (GRCm39) |
nonsense |
probably null |
|
|
IGL01637:Lrriq1
|
APN |
10 |
103,051,489 (GRCm39) |
missense |
probably benign |
|
|
IGL02019:Lrriq1
|
APN |
10 |
103,014,661 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02153:Lrriq1
|
APN |
10 |
103,006,340 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02341:Lrriq1
|
APN |
10 |
103,060,802 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02343:Lrriq1
|
APN |
10 |
103,070,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL02408:Lrriq1
|
APN |
10 |
102,982,142 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02431:Lrriq1
|
APN |
10 |
103,036,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Lrriq1
|
APN |
10 |
103,050,880 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02558:Lrriq1
|
APN |
10 |
102,982,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Lrriq1
|
APN |
10 |
102,980,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02642:Lrriq1
|
APN |
10 |
103,057,322 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03027:Lrriq1
|
APN |
10 |
103,063,057 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4362001:Lrriq1
|
UTSW |
10 |
102,907,055 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0124:Lrriq1
|
UTSW |
10 |
103,006,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0244:Lrriq1
|
UTSW |
10 |
103,051,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0323:Lrriq1
|
UTSW |
10 |
103,057,150 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0515:Lrriq1
|
UTSW |
10 |
102,904,829 (GRCm39) |
splice site |
probably null |
|
|
R0522:Lrriq1
|
UTSW |
10 |
102,997,638 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0701:Lrriq1
|
UTSW |
10 |
103,069,905 (GRCm39) |
missense |
probably benign |
|
|
R1220:Lrriq1
|
UTSW |
10 |
102,906,990 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1261:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1262:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1451:Lrriq1
|
UTSW |
10 |
103,038,376 (GRCm39) |
splice site |
probably benign |
|
|
R1642:Lrriq1
|
UTSW |
10 |
103,050,317 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1643:Lrriq1
|
UTSW |
10 |
103,050,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1647:Lrriq1
|
UTSW |
10 |
103,006,509 (GRCm39) |
nonsense |
probably null |
|
|
R1830:Lrriq1
|
UTSW |
10 |
102,997,620 (GRCm39) |
missense |
probably benign |
|
|
R1843:Lrriq1
|
UTSW |
10 |
103,063,034 (GRCm39) |
splice site |
probably null |
|
|
R2128:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2129:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2199:Lrriq1
|
UTSW |
10 |
102,904,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2354:Lrriq1
|
UTSW |
10 |
103,025,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Lrriq1
|
UTSW |
10 |
103,038,242 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2897:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2898:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2922:Lrriq1
|
UTSW |
10 |
103,050,536 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2939:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2965:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2966:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3081:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3115:Lrriq1
|
UTSW |
10 |
103,006,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3745:Lrriq1
|
UTSW |
10 |
103,006,717 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3813:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3814:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3885:Lrriq1
|
UTSW |
10 |
103,051,967 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4378:Lrriq1
|
UTSW |
10 |
103,038,225 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Lrriq1
|
UTSW |
10 |
103,057,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Lrriq1
|
UTSW |
10 |
103,036,424 (GRCm39) |
nonsense |
probably null |
|
|
R4663:Lrriq1
|
UTSW |
10 |
102,899,273 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4702:Lrriq1
|
UTSW |
10 |
103,051,610 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4793:Lrriq1
|
UTSW |
10 |
103,006,327 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4801:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4802:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4815:Lrriq1
|
UTSW |
10 |
102,980,739 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4872:Lrriq1
|
UTSW |
10 |
103,014,649 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4877:Lrriq1
|
UTSW |
10 |
103,069,899 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4894:Lrriq1
|
UTSW |
10 |
102,997,613 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4990:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4991:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5122:Lrriq1
|
UTSW |
10 |
103,023,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5282:Lrriq1
|
UTSW |
10 |
103,051,206 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5311:Lrriq1
|
UTSW |
10 |
103,050,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Lrriq1
|
UTSW |
10 |
103,006,457 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5643:Lrriq1
|
UTSW |
10 |
103,051,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5683:Lrriq1
|
UTSW |
10 |
103,009,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5916:Lrriq1
|
UTSW |
10 |
103,057,243 (GRCm39) |
nonsense |
probably null |
|
|
R6008:Lrriq1
|
UTSW |
10 |
103,006,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6022:Lrriq1
|
UTSW |
10 |
103,051,395 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6224:Lrriq1
|
UTSW |
10 |
103,051,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Lrriq1
|
UTSW |
10 |
103,051,312 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6311:Lrriq1
|
UTSW |
10 |
103,009,254 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6460:Lrriq1
|
UTSW |
10 |
103,036,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6502:Lrriq1
|
UTSW |
10 |
103,063,045 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6637:Lrriq1
|
UTSW |
10 |
103,057,293 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6719:Lrriq1
|
UTSW |
10 |
102,906,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6736:Lrriq1
|
UTSW |
10 |
103,017,750 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6928:Lrriq1
|
UTSW |
10 |
103,050,800 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6991:Lrriq1
|
UTSW |
10 |
103,023,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Lrriq1
|
UTSW |
10 |
103,060,826 (GRCm39) |
missense |
probably benign |
|
|
R7241:Lrriq1
|
UTSW |
10 |
103,051,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Lrriq1
|
UTSW |
10 |
103,059,611 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7287:Lrriq1
|
UTSW |
10 |
103,051,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7402:Lrriq1
|
UTSW |
10 |
103,057,185 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7439:Lrriq1
|
UTSW |
10 |
103,050,380 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7585:Lrriq1
|
UTSW |
10 |
103,050,807 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7611:Lrriq1
|
UTSW |
10 |
103,036,432 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7634:Lrriq1
|
UTSW |
10 |
103,036,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7767:Lrriq1
|
UTSW |
10 |
103,051,815 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7809:Lrriq1
|
UTSW |
10 |
103,051,678 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7910:Lrriq1
|
UTSW |
10 |
103,051,055 (GRCm39) |
nonsense |
probably null |
|
|
R8131:Lrriq1
|
UTSW |
10 |
103,051,572 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8156:Lrriq1
|
UTSW |
10 |
102,992,196 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8211:Lrriq1
|
UTSW |
10 |
103,006,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8304:Lrriq1
|
UTSW |
10 |
103,069,929 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Lrriq1
|
UTSW |
10 |
103,050,914 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8500:Lrriq1
|
UTSW |
10 |
102,882,016 (GRCm39) |
missense |
|
|
|
R9013:Lrriq1
|
UTSW |
10 |
103,050,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Lrriq1
|
UTSW |
10 |
103,051,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9155:Lrriq1
|
UTSW |
10 |
103,050,640 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9320:Lrriq1
|
UTSW |
10 |
103,057,144 (GRCm39) |
missense |
probably benign |
|
|
R9384:Lrriq1
|
UTSW |
10 |
103,006,458 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9585:Lrriq1
|
UTSW |
10 |
103,051,250 (GRCm39) |
missense |
probably benign |
|
|
R9706:Lrriq1
|
UTSW |
10 |
102,881,902 (GRCm39) |
missense |
|
|
|
R9780:Lrriq1
|
UTSW |
10 |
103,025,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Lrriq1
|
UTSW |
10 |
103,051,565 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Lrriq1
|
UTSW |
10 |
103,038,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,069,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTTGGGATTAGCATACAGTTGG -3'
(R):5'- CCCAACAGGTATGGATATAGATGC -3'
Sequencing Primer
(F):5'- CAACCTGGTCTATAGAGTGAGTTCC -3'
(R):5'- CCAGGTGGTTTAGAATCTTT -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation