Incidental Mutation 'R0437:Atp4a'
| ID |
39073 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atp4a
|
| Ensembl Gene |
ENSMUSG00000005553 |
| Gene Name |
ATPase, H+/K+ exchanging, gastric, alpha polypeptide |
| Synonyms |
H+K+-transporting alpha 1, H+/K+-ATPase alpha |
| MMRRC Submission |
038638-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.085)
|
| Stock # |
R0437 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
30411634-30424959 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to G
at 30419526 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glycine
at position 659
(R659G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131964
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000005692]
[ENSMUST00000170371]
[ENSMUST00000171014]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000005692
AA Change: R659G
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000005692
Gene: ENSMUSG00000005553
AA Change: R659G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:H-K_ATPase_N
|
2 |
42 |
5.4e-23 |
PFAM |
|
Cation_ATPase_N
|
52 |
126 |
2.26e-18 |
SMART |
|
Pfam:E1-E2_ATPase
|
144 |
375 |
1.1e-57 |
PFAM |
|
Pfam:Hydrolase
|
380 |
739 |
5.3e-16 |
PFAM |
|
Pfam:HAD
|
383 |
736 |
1.9e-18 |
PFAM |
|
Pfam:Cation_ATPase
|
436 |
531 |
1.6e-24 |
PFAM |
|
Pfam:Cation_ATPase_C
|
809 |
1019 |
4.8e-43 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165410
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167761
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170371
AA Change: R659G
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000131964
Gene: ENSMUSG00000005553
AA Change: R659G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:H-K_ATPase_N
|
2 |
42 |
4.9e-28 |
PFAM |
|
Cation_ATPase_N
|
52 |
126 |
2.26e-18 |
SMART |
|
Pfam:E1-E2_ATPase
|
145 |
376 |
1e-62 |
PFAM |
|
Pfam:Hydrolase
|
380 |
730 |
9.3e-25 |
PFAM |
|
Pfam:HAD
|
383 |
727 |
2.1e-15 |
PFAM |
|
Pfam:Hydrolase_like2
|
436 |
531 |
4e-25 |
PFAM |
|
Pfam:Cation_ATPase_C
|
800 |
1010 |
1.5e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171014
|
| Meta Mutation Damage Score |
0.0961 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.8%
|
| Validation Efficiency |
100% (104/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous mutation of this gene results in achlorhydria, hypergastrinemia, and abnormalities of the parietal cells. Mice homozygous for an ENU-induced allele exhibit iron-deficiency anemia. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(3) : Targeted, knock-out(1) Targeted, other(2) |
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4833420G17Rik |
G |
A |
13: 119,606,631 (GRCm39) |
R291K |
probably benign |
Het |
| Abca2 |
T |
C |
2: 25,332,857 (GRCm39) |
S1519P |
probably damaging |
Het |
| Abcb11 |
G |
A |
2: 69,087,639 (GRCm39) |
A1042V |
probably damaging |
Het |
| Abcc10 |
A |
T |
17: 46,623,845 (GRCm39) |
|
probably null |
Het |
| Abcc10 |
G |
T |
17: 46,623,846 (GRCm39) |
|
probably benign |
Het |
| Alkbh3 |
A |
C |
2: 93,811,914 (GRCm39) |
L240V |
probably damaging |
Het |
| Apol10b |
T |
C |
15: 77,469,608 (GRCm39) |
S190G |
probably benign |
Het |
| Atp1a3 |
C |
A |
7: 24,698,392 (GRCm39) |
C135F |
probably benign |
Het |
| Bicra |
A |
G |
7: 15,722,687 (GRCm39) |
S277P |
possibly damaging |
Het |
| Bltp1 |
A |
T |
3: 37,043,953 (GRCm39) |
H2820L |
possibly damaging |
Het |
| Bmp8a |
T |
C |
4: 123,210,690 (GRCm39) |
E275G |
probably benign |
Het |
| Ccdc102a |
T |
C |
8: 95,640,054 (GRCm39) |
E80G |
probably damaging |
Het |
| Cdh23 |
T |
C |
10: 60,246,576 (GRCm39) |
D954G |
probably damaging |
Het |
| Chrm4 |
A |
G |
2: 91,758,788 (GRCm39) |
T399A |
possibly damaging |
Het |
| Clcn3 |
A |
G |
8: 61,387,571 (GRCm39) |
V199A |
possibly damaging |
Het |
| Crlf1 |
T |
C |
8: 70,952,164 (GRCm39) |
|
probably null |
Het |
| Crx |
G |
T |
7: 15,605,071 (GRCm39) |
S57* |
probably null |
Het |
| Cstpp1 |
A |
G |
2: 91,252,298 (GRCm39) |
L21P |
probably damaging |
Het |
| Cyp4f16 |
A |
G |
17: 32,756,072 (GRCm39) |
I34V |
possibly damaging |
Het |
| Daxx |
T |
C |
17: 34,132,598 (GRCm39) |
V576A |
probably benign |
Het |
| Ddx17 |
C |
T |
15: 79,421,672 (GRCm39) |
R351H |
probably damaging |
Het |
| Dhx38 |
T |
C |
8: 110,285,261 (GRCm39) |
|
probably benign |
Het |
| Dnd1 |
T |
C |
18: 36,897,552 (GRCm39) |
|
probably benign |
Het |
| Dync1i2 |
A |
T |
2: 71,058,169 (GRCm39) |
|
probably null |
Het |
| E2f6 |
T |
C |
12: 16,866,446 (GRCm39) |
S52P |
probably benign |
Het |
| Epb41l4a |
A |
G |
18: 34,013,326 (GRCm39) |
F116S |
probably damaging |
Het |
| Ext1 |
T |
C |
15: 52,969,502 (GRCm39) |
N362S |
probably damaging |
Het |
| Fam227a |
C |
A |
15: 79,528,189 (GRCm39) |
K79N |
possibly damaging |
Het |
| Fam228a |
T |
A |
12: 4,782,759 (GRCm39) |
L111F |
probably damaging |
Het |
| Fat2 |
T |
C |
11: 55,173,625 (GRCm39) |
T2363A |
probably benign |
Het |
| Fat3 |
A |
T |
9: 15,908,228 (GRCm39) |
N2591K |
probably damaging |
Het |
| Frem2 |
A |
G |
3: 53,560,436 (GRCm39) |
M1357T |
possibly damaging |
Het |
| Frmd4b |
A |
T |
6: 97,400,424 (GRCm39) |
V29D |
probably damaging |
Het |
| G930045G22Rik |
A |
G |
6: 50,823,918 (GRCm39) |
|
noncoding transcript |
Het |
| Galnt3 |
A |
G |
2: 65,937,573 (GRCm39) |
S46P |
possibly damaging |
Het |
| Gmeb2 |
A |
G |
2: 180,895,766 (GRCm39) |
V468A |
possibly damaging |
Het |
| Herc2 |
C |
T |
7: 55,869,563 (GRCm39) |
R4271* |
probably null |
Het |
| Il5 |
C |
A |
11: 53,614,733 (GRCm39) |
|
probably benign |
Het |
| Ints9 |
G |
A |
14: 65,223,818 (GRCm39) |
|
probably benign |
Het |
| Itga10 |
T |
C |
3: 96,556,453 (GRCm39) |
F196S |
probably damaging |
Het |
| Itgb3bp |
T |
C |
4: 99,670,126 (GRCm39) |
T138A |
probably damaging |
Het |
| Kcnd1 |
G |
A |
X: 7,690,922 (GRCm39) |
V281M |
probably benign |
Het |
| Lcp2 |
T |
C |
11: 34,037,229 (GRCm39) |
L391P |
probably benign |
Het |
| Lrrc66 |
T |
C |
5: 73,765,030 (GRCm39) |
Y671C |
probably benign |
Het |
| Mettl23 |
T |
C |
11: 116,740,120 (GRCm39) |
V197A |
possibly damaging |
Het |
| Mmp15 |
C |
A |
8: 96,097,400 (GRCm39) |
D456E |
probably benign |
Het |
| Mospd4 |
T |
C |
18: 46,598,848 (GRCm39) |
|
noncoding transcript |
Het |
| Mov10l1 |
C |
A |
15: 88,889,515 (GRCm39) |
H484N |
probably damaging |
Het |
| Mphosph9 |
T |
C |
5: 124,453,631 (GRCm39) |
Q197R |
probably benign |
Het |
| Ms4a1 |
T |
A |
19: 11,233,933 (GRCm39) |
|
probably null |
Het |
| Mybbp1a |
T |
C |
11: 72,339,674 (GRCm39) |
V919A |
possibly damaging |
Het |
| Mycbpap |
A |
T |
11: 94,404,338 (GRCm39) |
|
probably benign |
Het |
| Naip6 |
G |
A |
13: 100,433,432 (GRCm39) |
S1135F |
possibly damaging |
Het |
| Ndufc2 |
T |
A |
7: 97,049,544 (GRCm39) |
M50K |
probably benign |
Het |
| Npr2 |
T |
C |
4: 43,648,082 (GRCm39) |
V842A |
probably damaging |
Het |
| Ntsr2 |
G |
T |
12: 16,703,696 (GRCm39) |
G66W |
probably damaging |
Het |
| Obscn |
T |
C |
11: 58,885,914 (GRCm39) |
|
probably benign |
Het |
| Optn |
C |
T |
2: 5,028,926 (GRCm39) |
G526R |
probably damaging |
Het |
| Or4c11 |
T |
A |
2: 88,695,229 (GRCm39) |
N93K |
probably benign |
Het |
| Or4c114 |
T |
A |
2: 88,904,956 (GRCm39) |
I160F |
probably benign |
Het |
| Or6c33 |
T |
C |
10: 129,853,965 (GRCm39) |
V245A |
probably damaging |
Het |
| Or6k14 |
G |
A |
1: 173,927,965 (GRCm39) |
G314R |
probably benign |
Het |
| Otud4 |
T |
A |
8: 80,396,626 (GRCm39) |
H628Q |
probably benign |
Het |
| Padi6 |
T |
C |
4: 140,456,240 (GRCm39) |
T585A |
probably benign |
Het |
| Pex16 |
G |
T |
2: 92,205,937 (GRCm39) |
R10L |
probably damaging |
Het |
| Pitpnm2 |
A |
G |
5: 124,269,152 (GRCm39) |
|
probably benign |
Het |
| Pom121l2 |
A |
G |
13: 22,167,375 (GRCm39) |
T549A |
possibly damaging |
Het |
| Prdm15 |
A |
T |
16: 97,613,759 (GRCm39) |
M470K |
probably benign |
Het |
| Prkag2 |
T |
A |
5: 25,233,503 (GRCm39) |
D49V |
possibly damaging |
Het |
| Prl3c1 |
A |
G |
13: 27,383,447 (GRCm39) |
M38V |
probably benign |
Het |
| Prpf18 |
T |
A |
2: 4,648,572 (GRCm39) |
I85F |
possibly damaging |
Het |
| Psg27 |
A |
G |
7: 18,294,636 (GRCm39) |
|
probably benign |
Het |
| Relt |
A |
G |
7: 100,497,991 (GRCm39) |
|
probably benign |
Het |
| Rskr |
T |
C |
11: 78,182,362 (GRCm39) |
L57P |
probably benign |
Het |
| Serpina3b |
A |
T |
12: 104,096,929 (GRCm39) |
N70I |
probably damaging |
Het |
| Slc19a3 |
T |
C |
1: 83,000,286 (GRCm39) |
S244G |
probably benign |
Het |
| Slc39a5 |
T |
C |
10: 128,235,716 (GRCm39) |
T81A |
possibly damaging |
Het |
| Slc7a2 |
G |
A |
8: 41,357,563 (GRCm39) |
G277D |
probably damaging |
Het |
| Slc9c1 |
C |
T |
16: 45,420,250 (GRCm39) |
|
probably benign |
Het |
| Slx1b |
A |
G |
7: 126,291,753 (GRCm39) |
F104L |
probably benign |
Het |
| Smg6 |
G |
A |
11: 74,820,527 (GRCm39) |
S266N |
probably damaging |
Het |
| Spata9 |
T |
C |
13: 76,146,614 (GRCm39) |
V162A |
possibly damaging |
Het |
| Szrd1 |
T |
C |
4: 140,846,055 (GRCm39) |
I47V |
probably benign |
Het |
| Tha1 |
G |
T |
11: 117,759,401 (GRCm39) |
L363M |
probably benign |
Het |
| Tmc6 |
G |
A |
11: 117,669,087 (GRCm39) |
T89I |
possibly damaging |
Het |
| Tmem132d |
C |
T |
5: 127,866,849 (GRCm39) |
G684R |
probably damaging |
Het |
| Trim55 |
G |
A |
3: 19,725,142 (GRCm39) |
G220S |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,600,874 (GRCm39) |
L18836P |
probably damaging |
Het |
| Ubn1 |
G |
T |
16: 4,890,048 (GRCm39) |
|
probably benign |
Het |
| Ush2a |
T |
G |
1: 188,643,228 (GRCm39) |
W4197G |
probably benign |
Het |
| Vmn1r189 |
A |
T |
13: 22,286,231 (GRCm39) |
V202E |
probably damaging |
Het |
| Vmn1r209 |
T |
C |
13: 22,990,526 (GRCm39) |
I55V |
probably benign |
Het |
| Vmn2r86 |
A |
T |
10: 130,282,412 (GRCm39) |
C735S |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,543,281 (GRCm39) |
D174V |
probably damaging |
Het |
| Zfp438 |
T |
C |
18: 5,214,910 (GRCm39) |
N16S |
probably damaging |
Het |
| Zfp444 |
C |
T |
7: 6,192,408 (GRCm39) |
T142I |
probably benign |
Het |
| Zfp804a |
A |
G |
2: 81,884,135 (GRCm39) |
M1V |
probably null |
Het |
| Zfp936 |
T |
G |
7: 42,838,734 (GRCm39) |
I67S |
probably benign |
Het |
| Zfp948 |
A |
T |
17: 21,807,260 (GRCm39) |
N151Y |
unknown |
Het |
|
| Other mutations in Atp4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Atp4a
|
APN |
7 |
30,412,629 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01327:Atp4a
|
APN |
7 |
30,412,675 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01510:Atp4a
|
APN |
7 |
30,420,216 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01763:Atp4a
|
APN |
7 |
30,414,943 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL02061:Atp4a
|
APN |
7 |
30,414,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02435:Atp4a
|
APN |
7 |
30,416,482 (GRCm39) |
missense |
probably benign |
|
|
IGL02903:Atp4a
|
APN |
7 |
30,415,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03181:Atp4a
|
APN |
7 |
30,424,129 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03350:Atp4a
|
APN |
7 |
30,420,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
atypical
|
UTSW |
7 |
30,414,781 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
sublytic
|
UTSW |
7 |
30,415,225 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03097:Atp4a
|
UTSW |
7 |
30,422,462 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0095:Atp4a
|
UTSW |
7 |
30,420,160 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0121:Atp4a
|
UTSW |
7 |
30,419,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0140:Atp4a
|
UTSW |
7 |
30,419,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0241:Atp4a
|
UTSW |
7 |
30,416,560 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0624:Atp4a
|
UTSW |
7 |
30,418,424 (GRCm39) |
missense |
probably benign |
|
|
R1164:Atp4a
|
UTSW |
7 |
30,417,117 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2105:Atp4a
|
UTSW |
7 |
30,419,793 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2272:Atp4a
|
UTSW |
7 |
30,414,925 (GRCm39) |
nonsense |
probably null |
|
|
R2327:Atp4a
|
UTSW |
7 |
30,419,666 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2881:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2990:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2992:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2993:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3123:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3125:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3441:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3442:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3686:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3687:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3845:Atp4a
|
UTSW |
7 |
30,416,540 (GRCm39) |
missense |
probably null |
0.99 |
|
R4027:Atp4a
|
UTSW |
7 |
30,424,377 (GRCm39) |
splice site |
probably null |
|
|
R4072:Atp4a
|
UTSW |
7 |
30,414,757 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4433:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4454:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4457:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4458:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4510:Atp4a
|
UTSW |
7 |
30,423,678 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atp4a
|
UTSW |
7 |
30,423,678 (GRCm39) |
nonsense |
probably null |
|
|
R4576:Atp4a
|
UTSW |
7 |
30,417,147 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4656:Atp4a
|
UTSW |
7 |
30,419,373 (GRCm39) |
intron |
probably benign |
|
|
R4661:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4662:Atp4a
|
UTSW |
7 |
30,419,650 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4852:Atp4a
|
UTSW |
7 |
30,423,693 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4892:Atp4a
|
UTSW |
7 |
30,411,899 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4907:Atp4a
|
UTSW |
7 |
30,418,517 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5024:Atp4a
|
UTSW |
7 |
30,415,289 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5254:Atp4a
|
UTSW |
7 |
30,414,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Atp4a
|
UTSW |
7 |
30,414,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5340:Atp4a
|
UTSW |
7 |
30,420,231 (GRCm39) |
missense |
probably benign |
|
|
R5484:Atp4a
|
UTSW |
7 |
30,420,097 (GRCm39) |
unclassified |
probably benign |
|
|
R5729:Atp4a
|
UTSW |
7 |
30,411,851 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5762:Atp4a
|
UTSW |
7 |
30,418,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5797:Atp4a
|
UTSW |
7 |
30,412,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Atp4a
|
UTSW |
7 |
30,421,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6030:Atp4a
|
UTSW |
7 |
30,421,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6077:Atp4a
|
UTSW |
7 |
30,415,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6243:Atp4a
|
UTSW |
7 |
30,415,382 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6346:Atp4a
|
UTSW |
7 |
30,414,781 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6459:Atp4a
|
UTSW |
7 |
30,411,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6515:Atp4a
|
UTSW |
7 |
30,411,903 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6773:Atp4a
|
UTSW |
7 |
30,414,802 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6854:Atp4a
|
UTSW |
7 |
30,414,433 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7215:Atp4a
|
UTSW |
7 |
30,416,785 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7271:Atp4a
|
UTSW |
7 |
30,421,944 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7340:Atp4a
|
UTSW |
7 |
30,416,155 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7457:Atp4a
|
UTSW |
7 |
30,420,192 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7593:Atp4a
|
UTSW |
7 |
30,424,105 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7712:Atp4a
|
UTSW |
7 |
30,414,978 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7762:Atp4a
|
UTSW |
7 |
30,419,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8714:Atp4a
|
UTSW |
7 |
30,420,013 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9324:Atp4a
|
UTSW |
7 |
30,415,207 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Atp4a
|
UTSW |
7 |
30,417,265 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1186:Atp4a
|
UTSW |
7 |
30,416,782 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGGGACATTGCTCTGATCTGAAGG -3'
(R):5'- CAATCACCAGCTTCTGCTGAGGAC -3'
Sequencing Primer
(F):5'- CTCTGATCTGAAGGGGTGAAG -3'
(R):5'- TCAGTCAGTGTGGGTTGCA -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation