Mutagenetix > Incidental Mutation

Incidental Mutation 'R5056:Dnah3'

390847

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

Dnahc3

MMRRC Submission

042646-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R5056 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

119521894-119694503 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 119620169 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 1587 (Y1587H)

Ref Sequence

ENSEMBL: ENSMUSP00000042857 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000046993
AA Change: Y1587H

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: Y1587H

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000209154
AA Change: Y1576H

PolyPhen 2 Score 0.278 (Sensitivity: 0.91; Specificity: 0.88)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Meta Mutation Damage Score

0.3789

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.0%
20x: 91.2%

Validation Efficiency

99% (73/74)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 66 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700030J22Rik	T	A	8: 117,698,421 (GRCm39)	K229*	probably null	Het
Adora2a	T	A	10: 75,161,992 (GRCm39)	S44T	probably damaging	Het
Agap3	T	C	5: 24,682,860 (GRCm39)	V459A	probably damaging	Het
Apc2	T	C	10: 80,137,148 (GRCm39)	V31A	probably benign	Het
Asic2	T	A	11: 80,862,429 (GRCm39)	K189N	possibly damaging	Het
Bbs10	C	T	10: 111,136,401 (GRCm39)	P505S	probably benign	Het
Brd10	A	T	19: 29,694,759 (GRCm39)	I1578K	probably benign	Het
Cdh20	G	T	1: 104,881,722 (GRCm39)	V396L	probably benign	Het
Cenpb	C	T	2: 131,020,091 (GRCm39)		probably benign	Het
Chil6	T	A	3: 106,301,659 (GRCm39)	Y147F	probably damaging	Het
Cluh	C	T	11: 74,552,772 (GRCm39)	R606C	probably damaging	Het
Cmtr1	A	G	17: 29,909,302 (GRCm39)	T404A	possibly damaging	Het
Cnot1	T	C	8: 96,467,636 (GRCm39)	N1499S	probably damaging	Het
Dmkn	T	C	7: 30,463,529 (GRCm39)	S61P	probably damaging	Het
Dmxl1	T	C	18: 50,003,990 (GRCm39)	C872R	probably benign	Het
Dsc2	A	T	18: 20,183,199 (GRCm39)	V73D	probably damaging	Het
F5	A	T	1: 164,019,601 (GRCm39)	Y692F	possibly damaging	Het
Fam184a	A	T	10: 53,550,670 (GRCm39)	L80I	probably damaging	Het
Foxj2	A	G	6: 122,810,833 (GRCm39)	H271R	probably benign	Het
Grm7	A	G	6: 111,057,404 (GRCm39)	T335A	probably damaging	Het
Hspa9	A	G	18: 35,071,734 (GRCm39)	L622P	probably damaging	Het
Kcna7	G	A	7: 45,056,015 (GRCm39)	R77H	probably damaging	Het
Kcnd3	T	A	3: 105,574,244 (GRCm39)		probably benign	Het
Klhdc8b	ACACGCACGCACGCACGCACGCACGCACGCACGCACGCAC	ACACGCACGCACGCACGCACGCACGCACGCACGCACGCACGCAC	9: 108,326,184 (GRCm39)		probably benign	Het
Klk14	G	A	7: 43,341,501 (GRCm39)	C51Y	probably damaging	Het
Lrch4	C	G	5: 137,635,113 (GRCm39)	N237K	probably damaging	Het
Lss	T	G	10: 76,388,760 (GRCm39)		probably null	Het
Map6	T	C	7: 98,985,859 (GRCm39)	F588L	probably benign	Het
Mbd6	C	T	10: 127,122,310 (GRCm39)	V173I	probably benign	Het
Med13	A	T	11: 86,219,391 (GRCm39)	S352T	probably benign	Het
Mettl16	T	A	11: 74,707,766 (GRCm39)	V320E	probably benign	Het
Myh7b	G	C	2: 155,474,293 (GRCm39)	R1669S	possibly damaging	Het
Nup188	T	A	2: 30,194,143 (GRCm39)	D149E	probably damaging	Het
Ogfrl1	A	G	1: 23,418,130 (GRCm39)	S83P	probably damaging	Het
Or52l1	T	A	7: 104,829,779 (GRCm39)	H262L	probably damaging	Het
Or5m13	T	A	2: 85,748,480 (GRCm39)	D70E	probably damaging	Het
Or8k36-ps1	T	A	2: 86,437,364 (GRCm39)	I184F	unknown	Het
Or9m1	T	C	2: 87,733,915 (GRCm39)	Y35C	probably damaging	Het
Pafah1b3	C	T	7: 24,994,764 (GRCm39)	R98Q	probably damaging	Het
Pde6b	A	T	5: 108,571,357 (GRCm39)	K437*	probably null	Het
Ppp1r12b	A	T	1: 134,762,130 (GRCm39)		probably benign	Het
Ppp1r12b	G	T	1: 134,883,471 (GRCm39)	A17E	probably benign	Het
Pramel34	T	C	5: 93,786,784 (GRCm39)		probably benign	Het
Prdm9	T	C	17: 15,782,679 (GRCm39)	Q104R	possibly damaging	Het
Rgs22	A	T	15: 36,050,391 (GRCm39)		probably null	Het
Rnf14	C	T	18: 38,441,441 (GRCm39)	P277L	probably damaging	Het
Robo4	T	C	9: 37,316,102 (GRCm39)	S258P	probably benign	Het
Sfrp1	T	A	8: 23,907,420 (GRCm39)	F207I	probably damaging	Het
Sgms1	A	G	19: 32,137,087 (GRCm39)	S160P	probably damaging	Het
Sil1	T	C	18: 35,402,755 (GRCm39)	K263R	probably benign	Het
St14	A	G	9: 31,008,847 (GRCm39)		probably null	Het
Syne2	A	G	12: 75,955,905 (GRCm39)		probably benign	Het
Tbc1d9	T	C	8: 83,995,835 (GRCm39)	S1013P	probably benign	Het
Tent5b	C	T	4: 133,207,749 (GRCm39)	R47W	possibly damaging	Het
Tmem67	T	C	4: 12,070,471 (GRCm39)	S352G	probably benign	Het
Trib2	C	A	12: 15,843,795 (GRCm39)	K282N	possibly damaging	Het
Trnau1ap	T	C	4: 132,054,482 (GRCm39)		probably benign	Het
Trpm4	T	C	7: 44,958,054 (GRCm39)	D952G	probably damaging	Het
Unc93b1	A	G	19: 3,992,762 (GRCm39)	N305D	possibly damaging	Het
Usp32	A	G	11: 84,917,621 (GRCm39)	V802A	probably benign	Het
Vmn2r48	T	A	7: 9,676,251 (GRCm39)	H410L	probably damaging	Het
Wfs1	T	C	5: 37,132,931 (GRCm39)	N116S	probably benign	Het
Wif1	A	T	10: 120,935,684 (GRCm39)	H333L	probably benign	Het
Zfp109	T	C	7: 23,928,162 (GRCm39)	T416A	possibly damaging	Het
Zfp808	T	A	13: 62,320,444 (GRCm39)	C558S	probably damaging	Het
Zpbp	T	C	11: 11,409,734 (GRCm39)	D116G	possibly damaging	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,538,128 (GRCm39)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,550,820 (GRCm39)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	119,622,164 (GRCm39)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,525,787 (GRCm39)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,566,943 (GRCm39)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,564,753 (GRCm39)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,542,798 (GRCm39)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,550,874 (GRCm39)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,550,437 (GRCm39)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	119,628,277 (GRCm39)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,550,494 (GRCm39)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,566,802 (GRCm39)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,550,215 (GRCm39)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,565,470 (GRCm39)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,538,137 (GRCm39)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,536,246 (GRCm39)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,564,720 (GRCm39)	missense	probably benign
IGL03404:Dnah3	APN	7	119,538,200 (GRCm39)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	119,618,924 (GRCm39)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	119,676,998 (GRCm39)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	119,644,882 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,564,882 (GRCm39)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,542,795 (GRCm39)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,527,977 (GRCm39)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	119,671,110 (GRCm39)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	119,620,138 (GRCm39)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,567,128 (GRCm39)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	119,629,274 (GRCm39)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R0972:Dnah3	UTSW	7	119,634,563 (GRCm39)	splice site	probably null
R1066:Dnah3	UTSW	7	119,660,232 (GRCm39)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	119,677,668 (GRCm39)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,522,253 (GRCm39)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,538,227 (GRCm39)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	119,689,899 (GRCm39)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,551,202 (GRCm39)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	119,646,853 (GRCm39)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	119,670,181 (GRCm39)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	119,618,918 (GRCm39)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,525,672 (GRCm39)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,570,402 (GRCm39)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,527,963 (GRCm39)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	119,645,009 (GRCm39)	splice site	probably null
R1711:Dnah3	UTSW	7	119,677,794 (GRCm39)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	119,634,582 (GRCm39)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,528,079 (GRCm39)	splice site	probably null
R1883:Dnah3	UTSW	7	119,677,142 (GRCm39)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	119,685,557 (GRCm39)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,567,182 (GRCm39)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,566,793 (GRCm39)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	119,694,400 (GRCm39)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,550,465 (GRCm39)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	119,638,629 (GRCm39)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,551,132 (GRCm39)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,566,982 (GRCm39)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,551,236 (GRCm39)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,550,792 (GRCm39)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	119,645,011 (GRCm39)	splice site	probably null
R2567:Dnah3	UTSW	7	119,551,920 (GRCm39)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,567,161 (GRCm39)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,550,722 (GRCm39)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,550,338 (GRCm39)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,550,333 (GRCm39)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	119,677,704 (GRCm39)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,550,303 (GRCm39)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	119,682,516 (GRCm39)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	119,628,248 (GRCm39)	nonsense	probably null
R4478:Dnah3	UTSW	7	119,671,086 (GRCm39)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	119,608,554 (GRCm39)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign
R4649:Dnah3	UTSW	7	119,646,921 (GRCm39)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	119,658,589 (GRCm39)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	119,677,169 (GRCm39)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	119,678,629 (GRCm39)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,567,047 (GRCm39)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	119,610,295 (GRCm39)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,550,904 (GRCm39)	nonsense	probably null
R4935:Dnah3	UTSW	7	119,615,700 (GRCm39)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,530,783 (GRCm39)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,555,424 (GRCm39)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,528,002 (GRCm39)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	119,671,128 (GRCm39)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,550,803 (GRCm39)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5069:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5154:Dnah3	UTSW	7	119,551,642 (GRCm39)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	119,631,861 (GRCm39)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	119,620,234 (GRCm39)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,542,871 (GRCm39)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,524,126 (GRCm39)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	119,689,299 (GRCm39)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,570,689 (GRCm39)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,570,844 (GRCm39)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,538,288 (GRCm39)	splice site	probably null
R5673:Dnah3	UTSW	7	119,550,812 (GRCm39)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	119,677,074 (GRCm39)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	119,658,421 (GRCm39)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,577,445 (GRCm39)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	119,689,175 (GRCm39)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,542,822 (GRCm39)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,530,696 (GRCm39)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	119,638,585 (GRCm39)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,538,056 (GRCm39)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,574,331 (GRCm39)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	119,668,927 (GRCm39)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	119,677,724 (GRCm39)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	119,615,749 (GRCm39)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,522,103 (GRCm39)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	119,672,764 (GRCm39)	missense	probably benign
R6004:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,566,745 (GRCm39)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	119,629,254 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	119,685,469 (GRCm39)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,564,711 (GRCm39)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	119,608,607 (GRCm39)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	119,653,856 (GRCm39)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,522,191 (GRCm39)	splice site	probably null
R6447:Dnah3	UTSW	7	119,522,277 (GRCm39)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	119,660,179 (GRCm39)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	119,670,172 (GRCm39)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,522,197 (GRCm39)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,570,950 (GRCm39)	missense	probably benign
R6882:Dnah3	UTSW	7	119,570,407 (GRCm39)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	119,653,824 (GRCm39)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	119,631,977 (GRCm39)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	119,629,233 (GRCm39)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,570,312 (GRCm39)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,521,965 (GRCm39)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	119,670,746 (GRCm39)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	119,631,893 (GRCm39)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,542,856 (GRCm39)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,580,567 (GRCm39)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	119,629,208 (GRCm39)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	119,628,239 (GRCm39)	missense	probably benign
R7375:Dnah3	UTSW	7	119,550,900 (GRCm39)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	119,660,183 (GRCm39)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,565,474 (GRCm39)	missense
R7431:Dnah3	UTSW	7	119,650,967 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	119,660,135 (GRCm39)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	119,672,815 (GRCm39)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,570,817 (GRCm39)	missense	probably benign
R7618:Dnah3	UTSW	7	119,577,601 (GRCm39)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,566,657 (GRCm39)	missense
R7728:Dnah3	UTSW	7	119,538,051 (GRCm39)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,570,438 (GRCm39)	splice site	probably null
R7757:Dnah3	UTSW	7	119,670,793 (GRCm39)	missense	probably benign
R7774:Dnah3	UTSW	7	119,550,975 (GRCm39)	nonsense	probably null
R7804:Dnah3	UTSW	7	119,610,235 (GRCm39)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,551,841 (GRCm39)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,550,927 (GRCm39)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,566,775 (GRCm39)	missense
R7903:Dnah3	UTSW	7	119,641,351 (GRCm39)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	119,677,012 (GRCm39)	missense	probably benign
R8142:Dnah3	UTSW	7	119,660,189 (GRCm39)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,566,837 (GRCm39)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,525,636 (GRCm39)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,550,375 (GRCm39)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	119,671,104 (GRCm39)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,551,728 (GRCm39)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	119,610,253 (GRCm39)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,536,253 (GRCm39)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,550,591 (GRCm39)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,561,375 (GRCm39)	missense
R8912:Dnah3	UTSW	7	119,689,869 (GRCm39)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,549,881 (GRCm39)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,536,294 (GRCm39)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,551,272 (GRCm39)	missense	probably benign
R9053:Dnah3	UTSW	7	119,618,987 (GRCm39)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	119,684,368 (GRCm39)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	119,684,351 (GRCm39)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,566,859 (GRCm39)	missense
R9383:Dnah3	UTSW	7	119,646,819 (GRCm39)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	119,628,205 (GRCm39)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,551,473 (GRCm39)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,551,523 (GRCm39)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	119,644,912 (GRCm39)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	119,650,951 (GRCm39)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	119,670,236 (GRCm39)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,561,356 (GRCm39)	missense
R9633:Dnah3	UTSW	7	119,550,216 (GRCm39)	missense	probably benign
R9654:Dnah3	UTSW	7	119,641,396 (GRCm39)	nonsense	probably null
R9665:Dnah3	UTSW	7	119,644,981 (GRCm39)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	119,677,611 (GRCm39)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,574,299 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	119,610,096 (GRCm39)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,567,026 (GRCm39)	missense
Z1177:Dnah3	UTSW	7	119,607,085 (GRCm39)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,567,124 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- ACTCTCAAAAGTGGGATGGC -3'
(R):5'- AAGCGTAGTTTCTGAAGGGGC -3'

Sequencing Primer
(F):5'- TCTCAAAAGTGGGATGGCTAGGATG -3'
(R):5'- GCTTCAATGAGGACCTGAAGTC -3'

Posted On

2016-06-06