Incidental Mutation 'R5027:Tnn'
| ID |
391401 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
tenascin-W, Tnw |
| MMRRC Submission |
042618-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.396)
|
| Stock # |
R5027 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159912599-159981150 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 159972781 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 274
(T274A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115685
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039178
AA Change: T274A
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: T274A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131919
AA Change: T274A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
AA Change: T274A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.3057 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.6%
|
| Validation Efficiency |
97% (97/100) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca14 |
T |
G |
7: 119,911,505 (GRCm39) |
I1363R |
probably benign |
Het |
| Abcc1 |
T |
C |
16: 14,221,917 (GRCm39) |
|
probably null |
Het |
| Adgrf1 |
T |
A |
17: 43,614,638 (GRCm39) |
F241I |
probably damaging |
Het |
| Afg3l1 |
T |
C |
8: 124,216,553 (GRCm39) |
M264T |
probably benign |
Het |
| Ankle1 |
T |
C |
8: 71,861,623 (GRCm39) |
S434P |
probably damaging |
Het |
| Apoe |
C |
T |
7: 19,430,940 (GRCm39) |
A101T |
probably damaging |
Het |
| Apol11a |
G |
T |
15: 77,401,153 (GRCm39) |
K213N |
probably damaging |
Het |
| Asap2 |
A |
G |
12: 21,254,082 (GRCm39) |
M198V |
probably damaging |
Het |
| Atg4b |
C |
T |
1: 93,714,297 (GRCm39) |
A360V |
probably benign |
Het |
| B3gnt5 |
T |
A |
16: 19,588,444 (GRCm39) |
V221D |
probably damaging |
Het |
| Baz2b |
A |
T |
2: 59,928,988 (GRCm39) |
|
probably benign |
Het |
| Cep350 |
C |
A |
1: 155,809,100 (GRCm39) |
W492L |
probably benign |
Het |
| Cln6 |
A |
G |
9: 62,754,375 (GRCm39) |
Y139C |
probably damaging |
Het |
| Col16a1 |
C |
T |
4: 129,972,988 (GRCm39) |
T643M |
probably benign |
Het |
| Cul9 |
C |
T |
17: 46,811,708 (GRCm39) |
E2507K |
probably damaging |
Het |
| Dgkz |
A |
T |
2: 91,775,888 (GRCm39) |
V125D |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,993,365 (GRCm39) |
M1127V |
probably benign |
Het |
| Dnajb1 |
C |
A |
8: 84,336,732 (GRCm39) |
D67E |
probably benign |
Het |
| Dync1li1 |
A |
G |
9: 114,542,612 (GRCm39) |
D258G |
probably damaging |
Het |
| Egflam |
G |
T |
15: 7,283,125 (GRCm39) |
P311T |
probably benign |
Het |
| Fbxw11 |
T |
A |
11: 32,602,811 (GRCm39) |
|
probably benign |
Het |
| Fn3krp |
T |
G |
11: 121,320,274 (GRCm39) |
D206E |
probably benign |
Het |
| Fsip2 |
A |
G |
2: 82,819,477 (GRCm39) |
H5070R |
possibly damaging |
Het |
| Gm6605 |
T |
C |
7: 38,149,683 (GRCm39) |
|
noncoding transcript |
Het |
| Gna14 |
C |
A |
19: 16,580,636 (GRCm39) |
T158K |
probably benign |
Het |
| Gstt2 |
A |
T |
10: 75,667,726 (GRCm39) |
I243N |
probably damaging |
Het |
| Haus6 |
C |
T |
4: 86,523,933 (GRCm39) |
D50N |
possibly damaging |
Het |
| Hcrtr2 |
A |
G |
9: 76,230,578 (GRCm39) |
I70T |
probably benign |
Het |
| Herc1 |
G |
A |
9: 66,380,811 (GRCm39) |
V3563I |
probably benign |
Het |
| Herc1 |
A |
T |
9: 66,411,900 (GRCm39) |
I4707F |
probably damaging |
Het |
| Hic2 |
C |
T |
16: 17,076,611 (GRCm39) |
A480V |
possibly damaging |
Het |
| Hsd17b3 |
A |
G |
13: 64,210,720 (GRCm39) |
Y212H |
probably damaging |
Het |
| Hspa5 |
A |
G |
2: 34,665,827 (GRCm39) |
K557R |
probably damaging |
Het |
| Iqch |
T |
C |
9: 63,432,294 (GRCm39) |
E367G |
possibly damaging |
Het |
| Itgb4 |
C |
T |
11: 115,874,983 (GRCm39) |
R447W |
probably benign |
Het |
| Lars2 |
A |
G |
9: 123,270,560 (GRCm39) |
M551V |
probably benign |
Het |
| Lbp |
T |
C |
2: 158,150,646 (GRCm39) |
I57T |
possibly damaging |
Het |
| Liat1 |
A |
G |
11: 75,891,047 (GRCm39) |
K54E |
probably damaging |
Het |
| Litaf |
T |
C |
16: 10,778,868 (GRCm39) |
Q142R |
possibly damaging |
Het |
| Lpar5 |
G |
C |
6: 125,059,110 (GRCm39) |
R277P |
possibly damaging |
Het |
| Muc6 |
T |
A |
7: 141,216,349 (GRCm39) |
I2710F |
probably benign |
Het |
| Myo7b |
T |
A |
18: 32,108,265 (GRCm39) |
I1199F |
probably benign |
Het |
| Naca |
A |
C |
10: 127,883,990 (GRCm39) |
E2140D |
possibly damaging |
Het |
| Nup214 |
G |
T |
2: 31,881,329 (GRCm39) |
G396C |
probably damaging |
Het |
| Or2v1 |
A |
T |
11: 49,025,451 (GRCm39) |
Q144L |
probably benign |
Het |
| Or5aq7 |
T |
A |
2: 86,938,150 (GRCm39) |
I194F |
probably benign |
Het |
| Or5j3 |
G |
A |
2: 86,128,540 (GRCm39) |
V127I |
possibly damaging |
Het |
| Or7g33 |
A |
G |
9: 19,448,573 (GRCm39) |
Y218H |
probably damaging |
Het |
| Or8b57 |
A |
T |
9: 40,003,690 (GRCm39) |
S187T |
probably damaging |
Het |
| P4htm |
A |
G |
9: 108,456,492 (GRCm39) |
V436A |
probably benign |
Het |
| Pfkm |
A |
G |
15: 98,017,307 (GRCm39) |
I117V |
possibly damaging |
Het |
| Phlpp1 |
T |
G |
1: 106,209,201 (GRCm39) |
V518G |
probably damaging |
Het |
| Piwil4 |
G |
A |
9: 14,621,240 (GRCm39) |
L598F |
probably damaging |
Het |
| Polr1b |
T |
G |
2: 128,965,803 (GRCm39) |
I815R |
possibly damaging |
Het |
| Ppef2 |
T |
C |
5: 92,382,150 (GRCm39) |
N515S |
probably damaging |
Het |
| Prp2rt |
A |
G |
13: 97,235,648 (GRCm39) |
I33T |
probably benign |
Het |
| Prpsap2 |
G |
T |
11: 61,631,830 (GRCm39) |
|
probably null |
Het |
| Rab27a |
A |
G |
9: 73,002,695 (GRCm39) |
D208G |
probably benign |
Het |
| Ralgds |
A |
G |
2: 28,442,102 (GRCm39) |
|
probably null |
Het |
| Raph1 |
C |
A |
1: 60,535,436 (GRCm39) |
C540F |
probably damaging |
Het |
| Rbsn |
A |
G |
6: 92,175,231 (GRCm39) |
L281P |
probably damaging |
Het |
| Rigi |
T |
A |
4: 40,208,845 (GRCm39) |
M756L |
probably benign |
Het |
| Rmdn1 |
G |
T |
4: 19,588,533 (GRCm39) |
G110* |
probably null |
Het |
| Rph3a |
T |
A |
5: 121,092,512 (GRCm39) |
E363V |
possibly damaging |
Het |
| Serpina16 |
G |
T |
12: 103,641,262 (GRCm39) |
Y154* |
probably null |
Het |
| Sh2d3c |
G |
A |
2: 32,634,814 (GRCm39) |
E198K |
possibly damaging |
Het |
| Shank2 |
C |
A |
7: 143,812,842 (GRCm39) |
Y663* |
probably null |
Het |
| Sharpin |
T |
C |
15: 76,234,225 (GRCm39) |
|
probably benign |
Het |
| Slitrk1 |
G |
A |
14: 109,149,740 (GRCm39) |
P324S |
probably benign |
Het |
| Sorbs2 |
T |
A |
8: 46,199,571 (GRCm39) |
|
probably null |
Het |
| Spag16 |
C |
T |
1: 69,962,963 (GRCm39) |
|
probably benign |
Het |
| Sycp2l |
A |
T |
13: 41,283,247 (GRCm39) |
|
probably null |
Het |
| Synj1 |
A |
T |
16: 90,737,407 (GRCm39) |
|
probably null |
Het |
| Sytl1 |
T |
C |
4: 132,983,530 (GRCm39) |
|
probably benign |
Het |
| Tkfc |
A |
T |
19: 10,570,023 (GRCm39) |
|
probably null |
Het |
| Trav14-2 |
T |
A |
14: 53,878,505 (GRCm39) |
W35R |
probably damaging |
Het |
| Trim72 |
T |
C |
7: 127,607,137 (GRCm39) |
M222T |
probably damaging |
Het |
| Trim9 |
A |
G |
12: 70,393,482 (GRCm39) |
V154A |
probably damaging |
Het |
| Ttc7b |
T |
C |
12: 100,268,001 (GRCm39) |
Y266C |
probably damaging |
Het |
| Uchl3 |
T |
A |
14: 101,903,982 (GRCm39) |
I43K |
possibly damaging |
Het |
| Vdac1 |
T |
A |
11: 52,279,305 (GRCm39) |
N269K |
possibly damaging |
Het |
| Wdr72 |
T |
A |
9: 74,053,258 (GRCm39) |
W187R |
probably damaging |
Het |
| Zfp30 |
T |
A |
7: 29,492,491 (GRCm39) |
C248* |
probably null |
Het |
| Zfp940 |
A |
T |
7: 29,550,381 (GRCm39) |
|
probably benign |
Het |
| Zfp980 |
G |
A |
4: 145,428,653 (GRCm39) |
G461S |
probably benign |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
159,953,021 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
159,925,776 (GRCm39) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
159,915,962 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
159,975,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
159,948,124 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
159,953,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
159,975,172 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
159,934,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
159,916,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
159,972,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
159,968,163 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
159,950,222 (GRCm39) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
159,942,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
159,913,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
159,968,347 (GRCm39) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
159,943,848 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
159,953,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
159,924,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
159,913,647 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
159,932,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
159,948,137 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
159,948,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
159,943,907 (GRCm39) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
159,952,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
159,952,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
159,924,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
159,945,978 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
159,975,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Tnn
|
UTSW |
1 |
159,972,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
159,975,154 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
159,968,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
159,943,752 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
159,924,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
159,968,170 (GRCm39) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
159,924,798 (GRCm39) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
159,938,079 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
159,966,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
159,934,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
159,973,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
159,924,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
159,972,681 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4701:Tnn
|
UTSW |
1 |
159,975,338 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4703:Tnn
|
UTSW |
1 |
159,943,815 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4737:Tnn
|
UTSW |
1 |
159,973,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4868:Tnn
|
UTSW |
1 |
159,958,443 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4977:Tnn
|
UTSW |
1 |
159,948,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Tnn
|
UTSW |
1 |
159,953,949 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5026:Tnn
|
UTSW |
1 |
159,973,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5049:Tnn
|
UTSW |
1 |
159,968,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
159,948,122 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
159,950,464 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
159,972,569 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
159,975,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
159,950,272 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
159,937,831 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
159,948,106 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
159,937,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
159,925,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
159,913,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
159,973,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
159,972,774 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
159,942,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
159,915,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
159,942,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
159,948,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
159,932,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
159,953,947 (GRCm39) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
159,934,687 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7340:Tnn
|
UTSW |
1 |
159,973,592 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7472:Tnn
|
UTSW |
1 |
159,937,917 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
159,937,929 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
159,946,074 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
159,915,984 (GRCm39) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
159,942,255 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
159,950,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
159,934,630 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
159,953,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
159,958,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
159,924,790 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
159,950,397 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
159,973,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
159,937,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
159,943,846 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
159,937,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
159,953,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
159,953,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
159,913,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
159,973,863 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
159,954,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGGAAATGTCTTTCTTCACG -3'
(R):5'- CAGTAACATCCAGGGGAACG -3'
Sequencing Primer
(F):5'- TCTTCACGTTGCGCAGG -3'
(R):5'- TAACATCCAGGGGAACGGTGTC -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation