Incidental Mutation 'R5032:Pik3c2g'
| ID |
391752 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3c2g
|
| Ensembl Gene |
ENSMUSG00000030228 |
| Gene Name |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
| Synonyms |
|
| MMRRC Submission |
042623-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.105)
|
| Stock # |
R5032 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
139591070-139915010 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 139841928 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 778
(T778S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087657]
[ENSMUST00000111868]
[ENSMUST00000218528]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000087657
AA Change: T410S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000084939
Gene: ENSMUSG00000030228
AA Change: T410S
| Domain | Start | End | E-Value | Type |
|---|
|
PI3Kc
|
125 |
387 |
2.11e-109 |
SMART |
|
PX
|
411 |
515 |
1.24e-21 |
SMART |
|
C2
|
550 |
647 |
1.34e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111868
AA Change: T778S
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000107499
Gene: ENSMUSG00000030228
AA Change: T778S
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa2
|
1 |
83 |
4e-16 |
SMART |
|
PI3Ka
|
103 |
288 |
7.6e-29 |
SMART |
|
PI3Kc
|
375 |
637 |
2.11e-109 |
SMART |
|
PX
|
661 |
765 |
1.24e-21 |
SMART |
|
C2
|
800 |
897 |
1.34e-7 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187448
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189374
|
| SMART Domains |
Protein: ENSMUSP00000139763
Gene: ENSMUSG00000030228
| Domain | Start | End | E-Value | Type |
|---|
|
PI3Kc
|
125 |
387 |
2.11e-109 |
SMART |
|
PX
|
411 |
515 |
1.24e-21 |
SMART |
|
C2
|
550 |
647 |
1.34e-7 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206646
AA Change: T410S
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000218528
AA Change: T660S
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| Meta Mutation Damage Score |
0.0693 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.6%
- 20x: 93.0%
|
| Validation Efficiency |
97% (77/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
PHENOTYPE: Mice homozygous for a knock-out allelel exhibit reduced liver glucogen accumulation, hyperlipidemia, adiposity and insulin resistance with age or after consumption of a high-fat diet. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700012B07Rik |
G |
T |
11: 109,684,980 (GRCm39) |
C172* |
probably null |
Het |
| Actl9 |
A |
G |
17: 33,653,062 (GRCm39) |
N374S |
probably benign |
Het |
| Adam34l |
T |
C |
8: 44,079,508 (GRCm39) |
N239D |
probably damaging |
Het |
| Ahcyl2 |
T |
A |
6: 29,768,555 (GRCm39) |
|
probably benign |
Het |
| Arfgef2 |
T |
C |
2: 166,720,464 (GRCm39) |
M1501T |
probably benign |
Het |
| Asb17 |
A |
T |
3: 153,550,175 (GRCm39) |
D69V |
probably damaging |
Het |
| Atp13a5 |
T |
C |
16: 29,082,202 (GRCm39) |
Y877C |
probably damaging |
Het |
| Atrip |
T |
C |
9: 108,894,271 (GRCm39) |
Q64R |
probably benign |
Het |
| Auts2 |
A |
G |
5: 131,505,730 (GRCm39) |
|
probably benign |
Het |
| Cacna2d1 |
G |
T |
5: 16,564,068 (GRCm39) |
R893L |
probably damaging |
Het |
| Ccdc138 |
C |
T |
10: 58,409,458 (GRCm39) |
R596C |
probably damaging |
Het |
| Cd163 |
A |
G |
6: 124,288,628 (GRCm39) |
Y353C |
probably damaging |
Het |
| Cdon |
T |
C |
9: 35,400,330 (GRCm39) |
Y1015H |
probably damaging |
Het |
| Chsy3 |
T |
C |
18: 59,312,543 (GRCm39) |
Y339H |
probably damaging |
Het |
| Cspp1 |
T |
C |
1: 10,136,744 (GRCm39) |
W190R |
probably benign |
Het |
| Ddx1 |
A |
T |
12: 13,273,993 (GRCm39) |
I570N |
probably damaging |
Het |
| Duox1 |
G |
A |
2: 122,167,798 (GRCm39) |
R1027H |
probably benign |
Het |
| Dync1h1 |
C |
T |
12: 110,593,326 (GRCm39) |
Q1198* |
probably null |
Het |
| Ecel1 |
G |
A |
1: 87,081,975 (GRCm39) |
S246L |
probably damaging |
Het |
| Fam228b |
T |
G |
12: 4,813,042 (GRCm39) |
R109S |
probably damaging |
Het |
| Fut9 |
T |
A |
4: 25,799,245 (GRCm39) |
|
probably benign |
Het |
| Gm5592 |
A |
G |
7: 40,939,159 (GRCm39) |
R814G |
probably damaging |
Het |
| Gmps |
A |
G |
3: 63,897,746 (GRCm39) |
K233E |
probably benign |
Het |
| Gramd1c |
A |
G |
16: 43,811,026 (GRCm39) |
Y438H |
probably damaging |
Het |
| Gsdmc |
A |
T |
15: 63,673,882 (GRCm39) |
D134E |
possibly damaging |
Het |
| Gxylt2 |
A |
G |
6: 100,760,142 (GRCm39) |
I226V |
probably benign |
Het |
| Hc |
T |
C |
2: 34,903,544 (GRCm39) |
I1037V |
probably benign |
Het |
| Hspa4 |
T |
G |
11: 53,179,950 (GRCm39) |
R69S |
possibly damaging |
Het |
| Hspg2 |
C |
T |
4: 137,246,251 (GRCm39) |
R1010C |
probably damaging |
Het |
| Kifc3 |
A |
G |
8: 95,829,354 (GRCm39) |
S508P |
probably damaging |
Het |
| Krt7 |
G |
A |
15: 101,310,428 (GRCm39) |
R25H |
probably benign |
Het |
| Lhfpl6 |
T |
A |
3: 52,950,854 (GRCm39) |
S43T |
possibly damaging |
Het |
| Lrrc7 |
T |
A |
3: 157,887,217 (GRCm39) |
K394N |
possibly damaging |
Het |
| Lypd4 |
A |
T |
7: 24,566,240 (GRCm39) |
L28Q |
probably damaging |
Het |
| Mdc1 |
A |
G |
17: 36,161,481 (GRCm39) |
E798G |
probably benign |
Het |
| Mta1 |
T |
A |
12: 113,097,145 (GRCm39) |
|
probably null |
Het |
| Mtg2 |
A |
T |
2: 179,725,183 (GRCm39) |
Q132L |
possibly damaging |
Het |
| Myh1 |
G |
T |
11: 67,096,874 (GRCm39) |
E382* |
probably null |
Het |
| Myo3a |
T |
C |
2: 22,287,413 (GRCm39) |
L175P |
probably damaging |
Het |
| Nckap5 |
A |
T |
1: 125,904,786 (GRCm39) |
F144L |
possibly damaging |
Het |
| Nfrkb |
T |
A |
9: 31,300,351 (GRCm39) |
|
probably null |
Het |
| Nmt2 |
C |
T |
2: 3,285,429 (GRCm39) |
P5L |
probably benign |
Het |
| Nsmf |
T |
C |
2: 24,945,073 (GRCm39) |
|
probably null |
Het |
| Oprl1 |
C |
T |
2: 181,360,795 (GRCm39) |
R257C |
probably damaging |
Het |
| Or51q1 |
A |
T |
7: 103,628,581 (GRCm39) |
M61L |
probably damaging |
Het |
| Or5a1 |
T |
A |
19: 12,097,420 (GRCm39) |
I219F |
probably benign |
Het |
| Pcdhgc3 |
T |
A |
18: 37,940,638 (GRCm39) |
N346K |
probably damaging |
Het |
| Pcnt |
G |
A |
10: 76,190,911 (GRCm39) |
P2791S |
probably benign |
Het |
| Pdia3 |
A |
G |
2: 121,244,620 (GRCm39) |
N11S |
probably benign |
Het |
| Pik3ip1 |
T |
A |
11: 3,283,520 (GRCm39) |
I75N |
probably damaging |
Het |
| Pla2g4d |
A |
T |
2: 120,112,176 (GRCm39) |
Y118* |
probably null |
Het |
| Ppargc1b |
A |
G |
18: 61,440,336 (GRCm39) |
S845P |
probably damaging |
Het |
| Prdm2 |
A |
T |
4: 142,905,937 (GRCm39) |
L50* |
probably null |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Pxdn |
G |
A |
12: 30,053,140 (GRCm39) |
V926I |
probably benign |
Het |
| Rab11fip2 |
A |
T |
19: 59,925,799 (GRCm39) |
N139K |
probably damaging |
Het |
| Rcn2 |
T |
A |
9: 55,960,300 (GRCm39) |
M189K |
probably damaging |
Het |
| Rev1 |
A |
T |
1: 38,113,570 (GRCm39) |
|
probably benign |
Het |
| Rhbg |
C |
A |
3: 88,152,441 (GRCm39) |
G368C |
probably damaging |
Het |
| Rnf214 |
A |
G |
9: 45,811,042 (GRCm39) |
|
probably null |
Het |
| Sf3a3 |
T |
C |
4: 124,618,959 (GRCm39) |
S307P |
probably benign |
Het |
| Slc6a18 |
T |
A |
13: 73,814,442 (GRCm39) |
Y494F |
probably damaging |
Het |
| Son |
T |
C |
16: 91,454,552 (GRCm39) |
S1100P |
probably damaging |
Het |
| Spag16 |
T |
G |
1: 69,892,511 (GRCm39) |
N97K |
probably benign |
Het |
| Tmem192 |
T |
C |
8: 65,412,163 (GRCm39) |
V114A |
possibly damaging |
Het |
| Urb1 |
G |
T |
16: 90,553,059 (GRCm39) |
P1901T |
probably benign |
Het |
| Vwa5b2 |
A |
G |
16: 20,419,459 (GRCm39) |
T601A |
probably damaging |
Het |
| Wdtc1 |
G |
T |
4: 133,036,162 (GRCm39) |
T126K |
possibly damaging |
Het |
| Xirp2 |
T |
C |
2: 67,356,014 (GRCm39) |
Y3592H |
possibly damaging |
Het |
| Xylt2 |
A |
T |
11: 94,560,842 (GRCm39) |
V232E |
probably damaging |
Het |
|
| Other mutations in Pik3c2g |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Pik3c2g
|
APN |
6 |
139,841,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01355:Pik3c2g
|
APN |
6 |
139,798,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01579:Pik3c2g
|
APN |
6 |
139,700,467 (GRCm39) |
nonsense |
probably null |
|
|
IGL01580:Pik3c2g
|
APN |
6 |
139,599,514 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01587:Pik3c2g
|
APN |
6 |
139,700,467 (GRCm39) |
nonsense |
probably null |
|
|
IGL01813:Pik3c2g
|
APN |
6 |
139,599,407 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL02218:Pik3c2g
|
APN |
6 |
139,806,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Pik3c2g
|
APN |
6 |
139,863,730 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL02480:Pik3c2g
|
APN |
6 |
139,798,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02721:Pik3c2g
|
APN |
6 |
139,682,699 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02967:Pik3c2g
|
APN |
6 |
139,913,554 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03221:Pik3c2g
|
APN |
6 |
139,718,133 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
FR4304:Pik3c2g
|
UTSW |
6 |
139,612,654 (GRCm39) |
frame shift |
probably null |
|
|
FR4340:Pik3c2g
|
UTSW |
6 |
139,612,654 (GRCm39) |
frame shift |
probably null |
|
|
FR4976:Pik3c2g
|
UTSW |
6 |
139,612,652 (GRCm39) |
frame shift |
probably null |
|
|
IGL02837:Pik3c2g
|
UTSW |
6 |
139,603,562 (GRCm39) |
nonsense |
probably null |
|
|
PIT4531001:Pik3c2g
|
UTSW |
6 |
139,805,096 (GRCm39) |
missense |
|
|
|
R0002:Pik3c2g
|
UTSW |
6 |
139,714,471 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0081:Pik3c2g
|
UTSW |
6 |
139,903,519 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0098:Pik3c2g
|
UTSW |
6 |
139,639,441 (GRCm39) |
missense |
unknown |
|
|
R0719:Pik3c2g
|
UTSW |
6 |
139,606,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0740:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0837:Pik3c2g
|
UTSW |
6 |
139,903,425 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pik3c2g
|
UTSW |
6 |
139,841,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1306:Pik3c2g
|
UTSW |
6 |
139,718,154 (GRCm39) |
missense |
probably benign |
|
|
R1501:Pik3c2g
|
UTSW |
6 |
139,789,796 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1591:Pik3c2g
|
UTSW |
6 |
139,693,904 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1666:Pik3c2g
|
UTSW |
6 |
139,612,634 (GRCm39) |
intron |
probably benign |
|
|
R1907:Pik3c2g
|
UTSW |
6 |
139,789,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Pik3c2g
|
UTSW |
6 |
139,846,112 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1982:Pik3c2g
|
UTSW |
6 |
139,599,546 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2171:Pik3c2g
|
UTSW |
6 |
139,801,012 (GRCm39) |
nonsense |
probably null |
|
|
R2188:Pik3c2g
|
UTSW |
6 |
139,798,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3777:Pik3c2g
|
UTSW |
6 |
139,599,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3778:Pik3c2g
|
UTSW |
6 |
139,599,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3965:Pik3c2g
|
UTSW |
6 |
139,801,018 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4076:Pik3c2g
|
UTSW |
6 |
139,798,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4078:Pik3c2g
|
UTSW |
6 |
139,612,608 (GRCm39) |
intron |
probably benign |
|
|
R4108:Pik3c2g
|
UTSW |
6 |
139,676,096 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4461:Pik3c2g
|
UTSW |
6 |
139,787,407 (GRCm39) |
intron |
probably benign |
|
|
R4474:Pik3c2g
|
UTSW |
6 |
139,610,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4509:Pik3c2g
|
UTSW |
6 |
139,665,732 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Pik3c2g
|
UTSW |
6 |
139,665,744 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4732:Pik3c2g
|
UTSW |
6 |
139,881,711 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4733:Pik3c2g
|
UTSW |
6 |
139,881,711 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4854:Pik3c2g
|
UTSW |
6 |
139,714,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Pik3c2g
|
UTSW |
6 |
139,913,528 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4959:Pik3c2g
|
UTSW |
6 |
139,789,657 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4973:Pik3c2g
|
UTSW |
6 |
139,789,657 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5071:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5072:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5073:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5074:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5107:Pik3c2g
|
UTSW |
6 |
139,612,623 (GRCm39) |
intron |
probably benign |
|
|
R5186:Pik3c2g
|
UTSW |
6 |
139,599,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5253:Pik3c2g
|
UTSW |
6 |
139,841,983 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5359:Pik3c2g
|
UTSW |
6 |
139,599,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Pik3c2g
|
UTSW |
6 |
139,665,808 (GRCm39) |
missense |
probably benign |
|
|
R5417:Pik3c2g
|
UTSW |
6 |
139,682,669 (GRCm39) |
missense |
probably benign |
|
|
R5435:Pik3c2g
|
UTSW |
6 |
139,661,581 (GRCm39) |
splice site |
probably null |
|
|
R5580:Pik3c2g
|
UTSW |
6 |
139,603,531 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5664:Pik3c2g
|
UTSW |
6 |
139,682,733 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5908:Pik3c2g
|
UTSW |
6 |
139,714,436 (GRCm39) |
missense |
|
|
|
R5914:Pik3c2g
|
UTSW |
6 |
139,599,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,842,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,599,137 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6298:Pik3c2g
|
UTSW |
6 |
139,603,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6382:Pik3c2g
|
UTSW |
6 |
139,665,724 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6480:Pik3c2g
|
UTSW |
6 |
139,676,195 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6917:Pik3c2g
|
UTSW |
6 |
139,841,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6929:Pik3c2g
|
UTSW |
6 |
139,903,502 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7022:Pik3c2g
|
UTSW |
6 |
139,599,061 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7144:Pik3c2g
|
UTSW |
6 |
139,606,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7213:Pik3c2g
|
UTSW |
6 |
139,805,990 (GRCm39) |
missense |
|
|
|
R7215:Pik3c2g
|
UTSW |
6 |
139,700,589 (GRCm39) |
missense |
|
|
|
R7332:Pik3c2g
|
UTSW |
6 |
139,841,981 (GRCm39) |
missense |
|
|
|
R7357:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7359:Pik3c2g
|
UTSW |
6 |
139,913,620 (GRCm39) |
missense |
unknown |
|
|
R7385:Pik3c2g
|
UTSW |
6 |
139,801,079 (GRCm39) |
missense |
|
|
|
R7455:Pik3c2g
|
UTSW |
6 |
139,913,643 (GRCm39) |
missense |
unknown |
|
|
R7651:Pik3c2g
|
UTSW |
6 |
139,599,070 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7888:Pik3c2g
|
UTSW |
6 |
139,842,470 (GRCm39) |
missense |
|
|
|
R7923:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7964:Pik3c2g
|
UTSW |
6 |
139,827,786 (GRCm39) |
missense |
|
|
|
R8005:Pik3c2g
|
UTSW |
6 |
139,599,067 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8371:Pik3c2g
|
UTSW |
6 |
139,881,782 (GRCm39) |
missense |
unknown |
|
|
R8724:Pik3c2g
|
UTSW |
6 |
139,913,619 (GRCm39) |
missense |
unknown |
|
|
R8733:Pik3c2g
|
UTSW |
6 |
139,714,426 (GRCm39) |
nonsense |
probably null |
|
|
R8809:Pik3c2g
|
UTSW |
6 |
139,714,436 (GRCm39) |
missense |
|
|
|
R8888:Pik3c2g
|
UTSW |
6 |
139,676,092 (GRCm39) |
nonsense |
probably null |
|
|
R8931:Pik3c2g
|
UTSW |
6 |
139,821,093 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9188:Pik3c2g
|
UTSW |
6 |
139,599,401 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9336:Pik3c2g
|
UTSW |
6 |
139,821,161 (GRCm39) |
missense |
|
|
|
R9383:Pik3c2g
|
UTSW |
6 |
139,827,742 (GRCm39) |
nonsense |
probably null |
|
|
R9524:Pik3c2g
|
UTSW |
6 |
139,606,768 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9531:Pik3c2g
|
UTSW |
6 |
139,841,926 (GRCm39) |
missense |
|
|
|
R9630:Pik3c2g
|
UTSW |
6 |
139,599,237 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9697:Pik3c2g
|
UTSW |
6 |
139,913,517 (GRCm39) |
missense |
unknown |
|
|
R9708:Pik3c2g
|
UTSW |
6 |
139,606,865 (GRCm39) |
missense |
probably benign |
|
|
R9717:Pik3c2g
|
UTSW |
6 |
139,841,910 (GRCm39) |
missense |
|
|
|
RF015:Pik3c2g
|
UTSW |
6 |
139,700,497 (GRCm39) |
missense |
|
|
|
RF032:Pik3c2g
|
UTSW |
6 |
139,612,656 (GRCm39) |
frame shift |
probably null |
|
|
X0024:Pik3c2g
|
UTSW |
6 |
139,805,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAAACATAAGGCCCAATG -3'
(R):5'- GGAACTGTTCCCTCTCATGG -3'
Sequencing Primer
(F):5'- CCCAATGATAAACAAAGCCATGGGG -3'
(R):5'- GCACAGACAGGTTTAGACT -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation