Mutagenetix > Incidental Mutation

Incidental Mutation 'R5101:Dnah10'

392351

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

042852-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5101 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

124725085-124834308 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 124832513 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 4399 (T4399A)

Ref Sequence

ENSEMBL: ENSMUSP00000114593 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000036206] [ENSMUST00000058440] [ENSMUST00000135495] [ENSMUST00000141137] [ENSMUST00000143268]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000036206

SMART Domains

Protein: ENSMUSP00000038075
Gene: ENSMUSG00000037979

Domain	Start	End	E-Value	Type
Pfam:CCDC92	7	63	1.5e-25	PFAM
low complexity region	72	84	N/A	INTRINSIC
low complexity region	106	120	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000058440
AA Change: T4456A

PolyPhen 2 Score 0.514 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: T4456A

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000135495

SMART Domains

Protein: ENSMUSP00000119438
Gene: ENSMUSG00000037979

Domain	Start	End	E-Value	Type
Pfam:CCDC92	6	59	2.9e-25	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000141137
AA Change: T4399A

PolyPhen 2 Score 0.514 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: T4399A

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000143268

SMART Domains

Protein: ENSMUSP00000114983
Gene: ENSMUSG00000037979

Domain	Start	End	E-Value	Type
Pfam:CCDC92	6	66	2.3e-25	PFAM
low complexity region	72	84	N/A	INTRINSIC
low complexity region	106	120	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000196708

Meta Mutation Damage Score

0.3930

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.4%
20x: 93.0%

Validation Efficiency

100% (57/57)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam17	T	C	12: 21,373,405 (GRCm38)	T10A	possibly damaging	Het
Adgrg3	T	C	8: 95,036,935 (GRCm38)	F288S	probably benign	Het
Ago2	A	G	15: 73,119,490 (GRCm38)	V533A	probably damaging	Het
Akap9	T	G	5: 4,001,748 (GRCm38)	V1505G	probably damaging	Het
Apob	T	C	12: 8,011,934 (GRCm38)	I3439T	probably benign	Het
C1qtnf7	T	A	5: 43,615,972 (GRCm38)	Y204*	probably null	Het
Cdc42bpb	T	C	12: 111,299,115 (GRCm38)	E1461G	probably damaging	Het
Cdh3	C	T	8: 106,541,392 (GRCm38)	A353V	possibly damaging	Het
Clec4d	A	G	6: 123,267,112 (GRCm38)	Y60C	probably damaging	Het
Cmya5	T	A	13: 93,091,603 (GRCm38)	T2326S	possibly damaging	Het
Cnot1	G	A	8: 95,760,187 (GRCm38)	L631F	possibly damaging	Het
Cntnap5a	C	T	1: 116,442,296 (GRCm38)	T881I	probably benign	Het
Col6a1	T	A	10: 76,709,906 (GRCm38)	T911S	unknown	Het
Ctsw	A	G	19: 5,465,675 (GRCm38)	V287A	probably benign	Het
Cyp2c23	T	C	19: 44,029,183 (GRCm38)	E2G	unknown	Het
Cytip	A	T	2: 58,147,899 (GRCm38)	I151N	probably damaging	Het
Dock3	A	T	9: 106,969,781 (GRCm38)	I883N	probably damaging	Het
Entpd3	A	G	9: 120,566,542 (GRCm38)	*530W	probably null	Het
Gm4787	G	C	12: 81,377,830 (GRCm38)	T518S	probably benign	Het
Gp1ba	G	A	11: 70,641,399 (GRCm38)	V664M	probably benign	Het
Gpd2	T	A	2: 57,355,901 (GRCm38)	I481N	probably damaging	Het
Gvin-ps5	T	C	7: 106,329,889 (GRCm38)		noncoding transcript	Het
Ildr2	A	G	1: 166,307,762 (GRCm38)	D342G	probably damaging	Het
Krt83	A	G	15: 101,487,510 (GRCm38)	I327T	probably benign	Het
Lats1	T	A	10: 7,712,584 (GRCm38)	C988*	probably null	Het
Lpin2	G	A	17: 71,243,970 (GRCm38)	W708*	probably null	Het
Mast4	T	C	13: 102,736,356 (GRCm38)	D2168G	probably benign	Het
Myo6	G	T	9: 80,270,039 (GRCm38)	E606*	probably null	Het
Nek7	A	G	1: 138,515,693 (GRCm38)	V174A	probably benign	Het
Nid1	T	A	13: 13,483,754 (GRCm38)	C695S	probably damaging	Het
Nme8	A	G	13: 19,690,847 (GRCm38)		probably null	Het
Nr2c2	T	C	6: 92,154,516 (GRCm38)		probably null	Het
Or1e16	AGCGGTCGTAGGC	AGC	11: 73,395,654 (GRCm38)		probably null	Het
Or2ag18	A	T	7: 106,806,213 (GRCm38)	I83K	possibly damaging	Het
Or4x11	A	G	2: 90,037,047 (GRCm38)	M43V	probably benign	Het
Or51ab3	G	A	7: 103,551,943 (GRCm38)	E53K	probably damaging	Het
Or9g19	A	G	2: 85,769,924 (GRCm38)	N41S	probably damaging	Het
Pms2	A	G	5: 143,928,188 (GRCm38)	D696G	probably damaging	Het
Psapl1	T	A	5: 36,204,150 (GRCm38)	C29S	probably damaging	Het
Scn3a	A	T	2: 65,461,506 (GRCm38)	V1632D	probably damaging	Het
Slc22a1	C	T	17: 12,667,242 (GRCm38)	G168D	probably damaging	Het
Smad4	A	G	18: 73,675,860 (GRCm38)	V112A	probably benign	Het
Smc4	T	C	3: 69,028,512 (GRCm38)	V796A	probably benign	Het
Smco4	A	G	9: 15,544,672 (GRCm38)	E18G	unknown	Het
Spata31e2	T	C	1: 26,683,336 (GRCm38)	E921G	possibly damaging	Het
Sugp2	A	G	8: 70,260,489 (GRCm38)	E1035G	probably damaging	Het
Syde2	T	C	3: 146,015,638 (GRCm38)	S820P	probably damaging	Het
Syn2	T	C	6: 115,263,899 (GRCm38)	L410P	probably damaging	Het
Tmem131l	T	C	3: 83,937,504 (GRCm38)	N466S	probably damaging	Het
Uba1y	T	G	Y: 821,447 (GRCm38)		probably null	Het
Unc79	T	C	12: 103,112,510 (GRCm38)	S1645P	probably damaging	Het
Vmn2r17	A	T	5: 109,428,351 (GRCm38)	S363C	probably damaging	Het
Vmn2r78	T	C	7: 86,922,355 (GRCm38)	Y458H	probably damaging	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,828,603 (GRCm38)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,746,616 (GRCm38)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,794,341 (GRCm38)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,775,512 (GRCm38)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,777,212 (GRCm38)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,779,154 (GRCm38)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,783,946 (GRCm38)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,821,341 (GRCm38)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,732,489 (GRCm38)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,803,328 (GRCm38)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,787,465 (GRCm38)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,768,927 (GRCm38)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,755,786 (GRCm38)	missense	probably benign
IGL01767:Dnah10	APN	5	124,743,737 (GRCm38)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,764,944 (GRCm38)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,783,921 (GRCm38)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,789,812 (GRCm38)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,804,746 (GRCm38)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,819,366 (GRCm38)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,833,423 (GRCm38)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,773,067 (GRCm38)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,773,819 (GRCm38)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,793,852 (GRCm38)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,821,287 (GRCm38)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,787,331 (GRCm38)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,799,005 (GRCm38)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,773,745 (GRCm38)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,826,863 (GRCm38)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,730,086 (GRCm38)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,798,014 (GRCm38)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,801,822 (GRCm38)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,763,133 (GRCm38)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,730,162 (GRCm38)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,764,886 (GRCm38)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,748,457 (GRCm38)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,817,643 (GRCm38)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,817,697 (GRCm38)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,754,290 (GRCm38)	missense	probably benign	0.06
frosty	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,829,529 (GRCm38)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,730,100 (GRCm38)	missense	probably benign
P0019:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
P0037:Dnah10	UTSW	5	124,817,992 (GRCm38)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,775,524 (GRCm38)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,726,902 (GRCm38)	missense	probably benign
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,830,744 (GRCm38)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,763,076 (GRCm38)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,834,075 (GRCm38)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,796,369 (GRCm38)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,823,352 (GRCm38)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,755,735 (GRCm38)	missense	probably benign
R0480:Dnah10	UTSW	5	124,808,851 (GRCm38)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,812,723 (GRCm38)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,775,250 (GRCm38)	splice site	probably null
R0599:Dnah10	UTSW	5	124,800,953 (GRCm38)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,750,812 (GRCm38)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,829,577 (GRCm38)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,797,938 (GRCm38)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,760,014 (GRCm38)	splice site	probably null
R1248:Dnah10	UTSW	5	124,755,823 (GRCm38)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,753,326 (GRCm38)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,774,986 (GRCm38)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,762,221 (GRCm38)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,798,945 (GRCm38)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,743,686 (GRCm38)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1479:Dnah10	UTSW	5	124,777,889 (GRCm38)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,754,239 (GRCm38)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,760,952 (GRCm38)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,829,614 (GRCm38)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,765,562 (GRCm38)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,760,091 (GRCm38)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,773,190 (GRCm38)	splice site	probably null
R1828:Dnah10	UTSW	5	124,761,279 (GRCm38)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,804,689 (GRCm38)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,832,526 (GRCm38)	splice site	probably null
R1893:Dnah10	UTSW	5	124,754,317 (GRCm38)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,758,430 (GRCm38)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,800,984 (GRCm38)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,782,268 (GRCm38)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,775,203 (GRCm38)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,833,988 (GRCm38)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,829,587 (GRCm38)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,746,704 (GRCm38)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,796,341 (GRCm38)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,814,674 (GRCm38)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,774,981 (GRCm38)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,761,237 (GRCm38)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,731,466 (GRCm38)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,819,221 (GRCm38)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,742,000 (GRCm38)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,762,865 (GRCm38)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,775,478 (GRCm38)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,817,670 (GRCm38)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,819,412 (GRCm38)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,796,258 (GRCm38)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,747,630 (GRCm38)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,773,031 (GRCm38)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,777,926 (GRCm38)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,730,137 (GRCm38)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,732,330 (GRCm38)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,819,925 (GRCm38)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,762,869 (GRCm38)	splice site	probably null
R4651:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,775,517 (GRCm38)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,747,745 (GRCm38)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,819,344 (GRCm38)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,773,132 (GRCm38)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,817,748 (GRCm38)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,762,196 (GRCm38)	missense	possibly damaging	0.79
R5105:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,779,258 (GRCm38)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,798,960 (GRCm38)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,787,420 (GRCm38)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,785,156 (GRCm38)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,791,787 (GRCm38)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,773,566 (GRCm38)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,743,629 (GRCm38)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,830,493 (GRCm38)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,753,168 (GRCm38)	missense	probably benign
R5587:Dnah10	UTSW	5	124,793,913 (GRCm38)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,742,026 (GRCm38)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,821,386 (GRCm38)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,747,746 (GRCm38)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,823,373 (GRCm38)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,808,729 (GRCm38)	missense	probably benign
R6021:Dnah10	UTSW	5	124,736,984 (GRCm38)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,801,860 (GRCm38)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,819,210 (GRCm38)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,805,897 (GRCm38)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,753,174 (GRCm38)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,785,175 (GRCm38)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,770,599 (GRCm38)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,823,318 (GRCm38)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,743,679 (GRCm38)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,794,219 (GRCm38)	splice site	probably null
R6275:Dnah10	UTSW	5	124,785,184 (GRCm38)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,775,080 (GRCm38)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,829,646 (GRCm38)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,809,269 (GRCm38)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,762,782 (GRCm38)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,758,355 (GRCm38)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,830,033 (GRCm38)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,760,159 (GRCm38)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,805,805 (GRCm38)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,808,812 (GRCm38)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,777,826 (GRCm38)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,790,000 (GRCm38)	splice site	probably null
R6932:Dnah10	UTSW	5	124,821,450 (GRCm38)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,787,426 (GRCm38)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,816,142 (GRCm38)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,822,945 (GRCm38)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,822,942 (GRCm38)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,813,828 (GRCm38)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,832,598 (GRCm38)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,821,269 (GRCm38)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,747,739 (GRCm38)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,799,031 (GRCm38)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,746,544 (GRCm38)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,817,712 (GRCm38)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,777,234 (GRCm38)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,782,361 (GRCm38)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,726,885 (GRCm38)	missense	probably benign
R7999:Dnah10	UTSW	5	124,725,258 (GRCm38)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,800,885 (GRCm38)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,746,612 (GRCm38)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,828,511 (GRCm38)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,754,266 (GRCm38)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,800,882 (GRCm38)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,755,726 (GRCm38)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,828,460 (GRCm38)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,750,794 (GRCm38)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,782,346 (GRCm38)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,832,502 (GRCm38)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,773,542 (GRCm38)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,736,831 (GRCm38)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,816,100 (GRCm38)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,726,847 (GRCm38)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,814,621 (GRCm38)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,775,346 (GRCm38)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,765,550 (GRCm38)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,818,117 (GRCm38)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,789,764 (GRCm38)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,800,951 (GRCm38)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,813,942 (GRCm38)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,736,993 (GRCm38)	missense
R9001:Dnah10	UTSW	5	124,775,451 (GRCm38)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,743,719 (GRCm38)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,828,077 (GRCm38)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,762,173 (GRCm38)	missense
R9133:Dnah10	UTSW	5	124,782,359 (GRCm38)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,830,411 (GRCm38)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,794,373 (GRCm38)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,741,925 (GRCm38)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,736,836 (GRCm38)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,768,926 (GRCm38)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,794,443 (GRCm38)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,746,613 (GRCm38)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,823,444 (GRCm38)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,830,043 (GRCm38)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,775,185 (GRCm38)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,818,077 (GRCm38)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,777,907 (GRCm38)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
U24488:Dnah10	UTSW	5	124,813,980 (GRCm38)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,765,697 (GRCm38)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,775,355 (GRCm38)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,741,955 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,817,988 (GRCm38)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,747,619 (GRCm38)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- AGTCCACCTAGAGTTCGGTG -3'
(R):5'- TCCACATGGTACTTGGATTTGG -3'

Sequencing Primer
(F):5'- CACCTAGAGTTCGGTGGTCAG -3'
(R):5'- CCACATGGTACTTGGATTTGGGAATG -3'

Posted On

2016-06-15