Incidental Mutation 'R5120:Ralgapa2'
| ID |
392903 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapa2
|
| Ensembl Gene |
ENSMUSG00000037110 |
| Gene Name |
Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Synonyms |
AS250, A230067G21Rik, RGC2 |
| MMRRC Submission |
042708-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.209)
|
| Stock # |
R5120 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
146081799-146354264 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 146254004 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 852
(T852K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153734
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000109986]
[ENSMUST00000131824]
[ENSMUST00000228797]
|
| AlphaFold |
A3KGS3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109986
AA Change: T805K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
AA Change: T805K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131824
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146024
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149499
|
| SMART Domains |
Protein: ENSMUSP00000122017
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
140 |
151 |
N/A |
INTRINSIC |
|
low complexity region
|
650 |
661 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
934 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1334 |
1511 |
2.4e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228797
AA Change: T852K
PolyPhen 2
Score 0.257 (Sensitivity: 0.91; Specificity: 0.88)
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.8%
- 20x: 90.6%
|
| Validation Efficiency |
100% (97/97) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence and severity of induced urothelial bladder tumors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310033P09Rik |
A |
G |
11: 59,101,061 (GRCm39) |
H225R |
probably benign |
Het |
| Abcc9 |
T |
A |
6: 142,602,344 (GRCm39) |
I690F |
probably benign |
Het |
| Acp4 |
A |
T |
7: 43,906,395 (GRCm39) |
D52E |
probably damaging |
Het |
| Adam17 |
T |
C |
12: 21,393,020 (GRCm39) |
|
probably benign |
Het |
| Adamts15 |
T |
C |
9: 30,832,872 (GRCm39) |
E221G |
probably damaging |
Het |
| Aoc2 |
A |
G |
11: 101,216,540 (GRCm39) |
T208A |
probably benign |
Het |
| Apoa4 |
T |
G |
9: 46,154,035 (GRCm39) |
I212S |
probably damaging |
Het |
| Bptf |
A |
T |
11: 106,964,211 (GRCm39) |
M1598K |
probably damaging |
Het |
| Camsap3 |
G |
A |
8: 3,650,680 (GRCm39) |
R209Q |
probably damaging |
Het |
| Ccdc171 |
C |
A |
4: 83,476,763 (GRCm39) |
|
probably benign |
Het |
| Celsr2 |
G |
C |
3: 108,300,436 (GRCm39) |
P2875A |
probably benign |
Het |
| Cenpb |
A |
G |
2: 131,021,738 (GRCm39) |
V20A |
probably benign |
Het |
| Cfap61 |
A |
T |
2: 145,985,080 (GRCm39) |
K975* |
probably null |
Het |
| Cfhr4 |
T |
C |
1: 139,680,841 (GRCm39) |
S226G |
probably benign |
Het |
| Col9a2 |
G |
T |
4: 120,896,969 (GRCm39) |
A20S |
unknown |
Het |
| Crnn |
A |
T |
3: 93,056,203 (GRCm39) |
I330F |
probably benign |
Het |
| Csf3r |
C |
A |
4: 125,929,620 (GRCm39) |
P381Q |
probably benign |
Het |
| Csmd3 |
G |
A |
15: 48,536,891 (GRCm39) |
Q104* |
probably null |
Het |
| Ctnna1 |
G |
A |
18: 35,315,607 (GRCm39) |
|
probably null |
Het |
| Cwf19l2 |
C |
T |
9: 3,418,761 (GRCm39) |
Q183* |
probably null |
Het |
| Ddx60 |
T |
C |
8: 62,398,940 (GRCm39) |
Y220H |
probably benign |
Het |
| Dhh |
T |
C |
15: 98,796,038 (GRCm39) |
Q39R |
probably benign |
Het |
| Dynlrb2 |
T |
A |
8: 117,242,437 (GRCm39) |
I89N |
possibly damaging |
Het |
| Dytn |
T |
C |
1: 63,662,202 (GRCm39) |
E645G |
probably benign |
Het |
| Efcab7 |
A |
G |
4: 99,754,688 (GRCm39) |
T287A |
probably damaging |
Het |
| Eogt |
A |
G |
6: 97,111,276 (GRCm39) |
V195A |
probably benign |
Het |
| Ep400 |
G |
T |
5: 110,904,224 (GRCm39) |
P125Q |
probably damaging |
Het |
| Fasn |
A |
G |
11: 120,702,217 (GRCm39) |
V1815A |
probably benign |
Het |
| Gm5866 |
T |
C |
5: 52,740,224 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8674 |
C |
A |
13: 50,055,984 (GRCm39) |
|
noncoding transcript |
Het |
| Gpat4 |
G |
T |
8: 23,670,218 (GRCm39) |
H270Q |
possibly damaging |
Het |
| Grik5 |
A |
G |
7: 24,710,065 (GRCm39) |
L890P |
probably damaging |
Het |
| Gsap |
A |
G |
5: 21,474,934 (GRCm39) |
N500S |
probably damaging |
Het |
| H2-M10.1 |
T |
C |
17: 36,636,048 (GRCm39) |
D173G |
probably benign |
Het |
| Igfn1 |
T |
A |
1: 135,901,240 (GRCm39) |
I413F |
possibly damaging |
Het |
| Ighv1-52 |
G |
T |
12: 115,109,406 (GRCm39) |
H17N |
probably benign |
Het |
| Kcnu1 |
T |
A |
8: 26,424,516 (GRCm39) |
D270E |
possibly damaging |
Het |
| Kif16b |
A |
C |
2: 142,690,259 (GRCm39) |
N274K |
probably damaging |
Het |
| Klk1b11 |
C |
T |
7: 43,648,446 (GRCm39) |
T151I |
probably benign |
Het |
| Krtap13 |
A |
G |
16: 88,548,458 (GRCm39) |
F10S |
probably damaging |
Het |
| Large1 |
A |
T |
8: 73,585,969 (GRCm39) |
I379N |
probably damaging |
Het |
| Lhx8 |
T |
C |
3: 154,017,332 (GRCm39) |
H301R |
probably damaging |
Het |
| Lrriq3 |
T |
C |
3: 154,835,021 (GRCm39) |
V252A |
probably benign |
Het |
| Lysmd3 |
T |
A |
13: 81,817,311 (GRCm39) |
I96N |
probably damaging |
Het |
| Mpeg1 |
C |
T |
19: 12,438,793 (GRCm39) |
Q84* |
probably null |
Het |
| Myoz1 |
C |
T |
14: 20,700,722 (GRCm39) |
G165D |
probably benign |
Het |
| Myt1 |
G |
A |
2: 181,439,413 (GRCm39) |
V312I |
probably benign |
Het |
| Ndufb7 |
T |
C |
8: 84,293,606 (GRCm39) |
|
probably benign |
Het |
| Numa1 |
C |
T |
7: 101,626,644 (GRCm39) |
T10M |
probably damaging |
Het |
| Or10d1b |
T |
A |
9: 39,613,366 (GRCm39) |
H233L |
probably benign |
Het |
| Or1e30 |
A |
C |
11: 73,677,790 (GRCm39) |
I9L |
probably benign |
Het |
| Or2g7 |
A |
T |
17: 38,378,157 (GRCm39) |
I32F |
probably damaging |
Het |
| Or4f14d |
A |
T |
2: 111,960,903 (GRCm39) |
D84E |
probably damaging |
Het |
| Or4k39 |
T |
C |
2: 111,239,585 (GRCm39) |
|
noncoding transcript |
Het |
| Osmr |
A |
T |
15: 6,856,756 (GRCm39) |
S464T |
probably benign |
Het |
| Pak5 |
G |
A |
2: 135,925,149 (GRCm39) |
H718Y |
probably damaging |
Het |
| Pan2 |
T |
A |
10: 128,150,864 (GRCm39) |
|
probably null |
Het |
| Pik3r4 |
T |
C |
9: 105,546,208 (GRCm39) |
S853P |
probably benign |
Het |
| Pnkp |
C |
T |
7: 44,511,827 (GRCm39) |
S113L |
probably damaging |
Het |
| Polr3gl |
T |
A |
3: 96,485,795 (GRCm39) |
|
probably benign |
Het |
| Psd2 |
G |
A |
18: 36,112,863 (GRCm39) |
R186Q |
possibly damaging |
Het |
| Psd4 |
T |
C |
2: 24,295,450 (GRCm39) |
V868A |
probably benign |
Het |
| Rbm43 |
T |
C |
2: 51,822,435 (GRCm39) |
|
probably benign |
Het |
| Rps6kl1 |
C |
A |
12: 85,186,122 (GRCm39) |
G329C |
probably damaging |
Het |
| Scaf11 |
T |
C |
15: 96,317,423 (GRCm39) |
T714A |
probably benign |
Het |
| Selenoo |
C |
A |
15: 88,978,508 (GRCm39) |
N310K |
possibly damaging |
Het |
| Sepsecs |
T |
C |
5: 52,818,003 (GRCm39) |
Q258R |
probably damaging |
Het |
| Sgcz |
T |
C |
8: 37,993,420 (GRCm39) |
S226G |
probably benign |
Het |
| Slfn5 |
A |
G |
11: 82,851,754 (GRCm39) |
K627E |
probably damaging |
Het |
| Sos1 |
A |
T |
17: 80,715,677 (GRCm39) |
F1027I |
probably damaging |
Het |
| Ssh1 |
C |
G |
5: 114,095,459 (GRCm39) |
V228L |
possibly damaging |
Het |
| Sugp1 |
C |
A |
8: 70,501,317 (GRCm39) |
P65T |
probably benign |
Het |
| Tas2r106 |
T |
A |
6: 131,655,779 (GRCm39) |
N24I |
probably damaging |
Het |
| Tex10 |
T |
C |
4: 48,459,272 (GRCm39) |
E534G |
possibly damaging |
Het |
| Tmem182 |
C |
T |
1: 40,894,061 (GRCm39) |
T192I |
possibly damaging |
Het |
| Traf7 |
T |
A |
17: 24,737,718 (GRCm39) |
K51* |
probably null |
Het |
| Trap1 |
C |
A |
16: 3,861,952 (GRCm39) |
R604L |
probably damaging |
Het |
| Trim6 |
T |
A |
7: 103,877,447 (GRCm39) |
L179Q |
probably damaging |
Het |
| Ubfd1 |
T |
C |
7: 121,670,973 (GRCm39) |
S264P |
probably damaging |
Het |
| Upk3bl |
T |
C |
5: 136,093,045 (GRCm39) |
|
probably benign |
Het |
| Wdfy3 |
T |
A |
5: 102,015,972 (GRCm39) |
Q2601L |
possibly damaging |
Het |
| Wdr89 |
A |
G |
12: 75,679,412 (GRCm39) |
Y281H |
probably damaging |
Het |
| Zfp286 |
A |
T |
11: 62,671,551 (GRCm39) |
M174K |
probably benign |
Het |
| Zmym1 |
T |
C |
4: 126,945,230 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Ralgapa2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00666:Ralgapa2
|
APN |
2 |
146,327,056 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL00915:Ralgapa2
|
APN |
2 |
146,184,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01012:Ralgapa2
|
APN |
2 |
146,263,659 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,113 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01902:Ralgapa2
|
APN |
2 |
146,156,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ralgapa2
|
APN |
2 |
146,190,360 (GRCm39) |
splice site |
probably benign |
|
|
IGL02321:Ralgapa2
|
APN |
2 |
146,254,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Ralgapa2
|
APN |
2 |
146,254,052 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03026:Ralgapa2
|
APN |
2 |
146,302,695 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Ralgapa2
|
APN |
2 |
146,266,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03256:Ralgapa2
|
APN |
2 |
146,302,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03379:Ralgapa2
|
APN |
2 |
146,199,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
Chow
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
purina
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P4748:Ralgapa2
|
UTSW |
2 |
146,188,731 (GRCm39) |
nonsense |
probably null |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0165:Ralgapa2
|
UTSW |
2 |
146,230,407 (GRCm39) |
splice site |
probably benign |
|
|
R0344:Ralgapa2
|
UTSW |
2 |
146,188,714 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0402:Ralgapa2
|
UTSW |
2 |
146,276,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0419:Ralgapa2
|
UTSW |
2 |
146,270,592 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0638:Ralgapa2
|
UTSW |
2 |
146,184,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0704:Ralgapa2
|
UTSW |
2 |
146,293,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0722:Ralgapa2
|
UTSW |
2 |
146,230,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0866:Ralgapa2
|
UTSW |
2 |
146,277,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1065:Ralgapa2
|
UTSW |
2 |
146,292,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1212:Ralgapa2
|
UTSW |
2 |
146,199,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1395:Ralgapa2
|
UTSW |
2 |
146,230,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1614:Ralgapa2
|
UTSW |
2 |
146,230,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Ralgapa2
|
UTSW |
2 |
146,199,920 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1799:Ralgapa2
|
UTSW |
2 |
146,184,648 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1905:Ralgapa2
|
UTSW |
2 |
146,229,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Ralgapa2
|
UTSW |
2 |
146,302,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Ralgapa2
|
UTSW |
2 |
146,230,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2148:Ralgapa2
|
UTSW |
2 |
146,273,807 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2219:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2220:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2261:Ralgapa2
|
UTSW |
2 |
146,184,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2402:Ralgapa2
|
UTSW |
2 |
146,195,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ralgapa2
|
UTSW |
2 |
146,203,320 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3752:Ralgapa2
|
UTSW |
2 |
146,263,551 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3953:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3956:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4177:Ralgapa2
|
UTSW |
2 |
146,327,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4182:Ralgapa2
|
UTSW |
2 |
146,277,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Ralgapa2
|
UTSW |
2 |
146,184,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Ralgapa2
|
UTSW |
2 |
146,102,288 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4507:Ralgapa2
|
UTSW |
2 |
146,195,168 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4574:Ralgapa2
|
UTSW |
2 |
146,277,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4585:Ralgapa2
|
UTSW |
2 |
146,156,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4627:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4647:Ralgapa2
|
UTSW |
2 |
146,229,549 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4677:Ralgapa2
|
UTSW |
2 |
146,187,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4724:Ralgapa2
|
UTSW |
2 |
146,187,453 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4760:Ralgapa2
|
UTSW |
2 |
146,188,669 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4831:Ralgapa2
|
UTSW |
2 |
146,246,987 (GRCm39) |
intron |
probably benign |
|
|
R4962:Ralgapa2
|
UTSW |
2 |
146,276,754 (GRCm39) |
nonsense |
probably null |
|
|
R4993:Ralgapa2
|
UTSW |
2 |
146,289,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5041:Ralgapa2
|
UTSW |
2 |
146,327,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5185:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R5393:Ralgapa2
|
UTSW |
2 |
146,187,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5428:Ralgapa2
|
UTSW |
2 |
146,176,414 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5439:Ralgapa2
|
UTSW |
2 |
146,184,430 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5476:Ralgapa2
|
UTSW |
2 |
146,289,356 (GRCm39) |
missense |
probably benign |
|
|
R5695:Ralgapa2
|
UTSW |
2 |
146,175,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Ralgapa2
|
UTSW |
2 |
146,291,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ralgapa2
|
UTSW |
2 |
146,295,326 (GRCm39) |
splice site |
probably null |
|
|
R5817:Ralgapa2
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Ralgapa2
|
UTSW |
2 |
146,230,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6048:Ralgapa2
|
UTSW |
2 |
146,276,765 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6158:Ralgapa2
|
UTSW |
2 |
146,266,596 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6169:Ralgapa2
|
UTSW |
2 |
146,292,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6280:Ralgapa2
|
UTSW |
2 |
146,184,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6301:Ralgapa2
|
UTSW |
2 |
146,169,331 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6650:Ralgapa2
|
UTSW |
2 |
146,230,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Ralgapa2
|
UTSW |
2 |
146,184,621 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7020:Ralgapa2
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
R7035:Ralgapa2
|
UTSW |
2 |
146,353,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Ralgapa2
|
UTSW |
2 |
146,190,374 (GRCm39) |
missense |
probably benign |
|
|
R7186:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R7252:Ralgapa2
|
UTSW |
2 |
146,184,671 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7266:Ralgapa2
|
UTSW |
2 |
146,176,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7371:Ralgapa2
|
UTSW |
2 |
146,189,046 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7432:Ralgapa2
|
UTSW |
2 |
146,276,776 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7470:Ralgapa2
|
UTSW |
2 |
146,266,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7663:Ralgapa2
|
UTSW |
2 |
146,260,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7780:Ralgapa2
|
UTSW |
2 |
146,184,334 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7973:Ralgapa2
|
UTSW |
2 |
146,230,481 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8018:Ralgapa2
|
UTSW |
2 |
146,182,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Ralgapa2
|
UTSW |
2 |
146,285,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Ralgapa2
|
UTSW |
2 |
146,195,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8264:Ralgapa2
|
UTSW |
2 |
146,175,370 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8309:Ralgapa2
|
UTSW |
2 |
146,246,786 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8409:Ralgapa2
|
UTSW |
2 |
146,086,897 (GRCm39) |
missense |
|
|
|
R8474:Ralgapa2
|
UTSW |
2 |
146,266,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8487:Ralgapa2
|
UTSW |
2 |
146,230,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8492:Ralgapa2
|
UTSW |
2 |
146,184,524 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8733:Ralgapa2
|
UTSW |
2 |
146,266,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8856:Ralgapa2
|
UTSW |
2 |
146,184,139 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8858:Ralgapa2
|
UTSW |
2 |
146,102,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8862:Ralgapa2
|
UTSW |
2 |
146,266,731 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9146:Ralgapa2
|
UTSW |
2 |
146,184,252 (GRCm39) |
missense |
probably benign |
|
|
R9324:Ralgapa2
|
UTSW |
2 |
146,302,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9439:Ralgapa2
|
UTSW |
2 |
146,254,058 (GRCm39) |
missense |
probably benign |
|
|
R9457:Ralgapa2
|
UTSW |
2 |
146,176,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF019:Ralgapa2
|
UTSW |
2 |
146,203,423 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
X0019:Ralgapa2
|
UTSW |
2 |
146,230,572 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1088:Ralgapa2
|
UTSW |
2 |
146,276,825 (GRCm39) |
missense |
probably benign |
0.20 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCTCAGGCCTTACTTAGTG -3'
(R):5'- CAAAGCCATAGGTTTTGTCTTGG -3'
Sequencing Primer
(F):5'- AGGCCTTACTTAGTGTCTTTCC -3'
(R):5'- TCTGGAGTCCAAAGGTTGAC -3'
|
| Posted On |
2016-06-15 |
Incidental Mutation