Mutagenetix > Incidental Mutation

Incidental Mutation 'R5133:Baz2b'

395902

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

MMRRC Submission

042721-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.287) question?

Stock #

R5133 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

59729707-60040183 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 59792368 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 587 (S587T)

Ref Sequence

ENSEMBL: ENSMUSP00000108169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

probably benign
Transcript: ENSMUST00000090925
AA Change: S587T

PolyPhen 2 Score 0.119 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: S587T

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000112550
AA Change: S587T

PolyPhen 2 Score 0.119 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: S587T

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000135722

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 96.9%
20x: 94.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 101 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A3galt2	A	T	4: 128,655,934 (GRCm39)	T101S	probably damaging	Het
Abraxas2	C	T	7: 132,484,875 (GRCm39)	A306V	probably benign	Het
Acvr1c	T	A	2: 58,173,518 (GRCm39)	N248I	probably damaging	Het
Adgrv1	C	T	13: 81,587,560 (GRCm39)	R4537Q	probably damaging	Het
Adrb3	A	C	8: 27,717,798 (GRCm39)	M217R	probably damaging	Het
Afg3l1	T	C	8: 124,216,532 (GRCm39)	V257A	probably benign	Het
Agbl1	C	A	7: 76,071,904 (GRCm39)	Q334K	probably benign	Het
Aox4	A	T	1: 58,275,835 (GRCm39)	D389V	probably benign	Het
Apob	A	T	12: 8,058,898 (GRCm39)	Q2427L	probably damaging	Het
Asxl3	T	C	18: 22,649,765 (GRCm39)	C585R	probably damaging	Het
Baz2a	G	A	10: 127,951,995 (GRCm39)	G571D	probably damaging	Het
Bicdl2	T	C	17: 23,880,795 (GRCm39)	L14P	unknown	Het
Cachd1	G	A	4: 100,851,935 (GRCm39)	S1177N	probably damaging	Het
Cacna2d3	A	G	14: 29,015,135 (GRCm39)	F86L	possibly damaging	Het
Ccdc192	C	T	18: 57,697,041 (GRCm39)	T65I	possibly damaging	Het
Cd3d	A	T	9: 44,896,296 (GRCm39)	E28D	probably damaging	Het
Cmya5	T	C	13: 93,229,880 (GRCm39)	K1736R	possibly damaging	Het
Col12a1	A	G	9: 79,512,456 (GRCm39)	V2913A	probably damaging	Het
Cops8	A	G	1: 90,538,724 (GRCm39)	D51G	probably damaging	Het
Csgalnact1	T	C	8: 68,913,623 (GRCm39)	E194G	probably benign	Het
Csn1s1	A	G	5: 87,828,737 (GRCm39)	D267G	possibly damaging	Het
Cyp2c40	T	C	19: 39,795,663 (GRCm39)	N172S	probably benign	Het
Dhtkd1	T	A	2: 5,908,813 (GRCm39)	K760N	probably damaging	Het
Dnah17	T	C	11: 118,007,939 (GRCm39)	K691E	probably benign	Het
Dppa4	G	A	16: 48,113,334 (GRCm39)	R189Q	probably benign	Het
Dsp	G	A	13: 38,381,678 (GRCm39)	D2808N	possibly damaging	Het
Egr2	A	G	10: 67,375,605 (GRCm39)	E17G	probably damaging	Het
Ehmt1	G	T	2: 24,767,509 (GRCm39)	P135T	probably damaging	Het
Epas1	A	G	17: 87,116,882 (GRCm39)	N184S	probably damaging	Het
Ezh2	C	T	6: 47,517,684 (GRCm39)	C584Y	probably damaging	Het
F10	T	C	8: 13,105,698 (GRCm39)	V421A	probably damaging	Het
Fabp3	C	T	4: 130,206,180 (GRCm39)	T57I	probably benign	Het
Fam186a	T	G	15: 99,853,374 (GRCm39)	D122A	unknown	Het
Fam227b	G	A	2: 125,958,043 (GRCm39)	P241S	probably damaging	Het
Fam234b	T	C	6: 135,186,193 (GRCm39)	V67A	probably benign	Het
Fbn2	T	C	18: 58,172,412 (GRCm39)	D2131G	probably damaging	Het
Fgfr4	T	C	13: 55,307,828 (GRCm39)	Y271H	probably damaging	Het
Gnmt	A	T	17: 47,036,860 (GRCm39)	S250T	probably benign	Het
Golgb1	C	A	16: 36,711,819 (GRCm39)	Q208K	possibly damaging	Het
Grn	C	A	11: 102,321,380 (GRCm39)		probably benign	Het
Grwd1	T	C	7: 45,475,298 (GRCm39)	T415A	probably benign	Het
Gsk3b	G	A	16: 38,060,882 (GRCm39)	R418H	probably damaging	Het
Hap1	T	G	11: 100,242,357 (GRCm39)	M382L	probably benign	Het
Hspa12b	A	G	2: 130,981,428 (GRCm39)	E221G	possibly damaging	Het
Hspa4l	T	A	3: 40,741,179 (GRCm39)	D709E	possibly damaging	Het
Il17ra	A	G	6: 120,458,514 (GRCm39)	E555G	possibly damaging	Het
Il27ra	T	C	8: 84,760,688 (GRCm39)	T426A	possibly damaging	Het
Jup	T	C	11: 100,273,941 (GRCm39)	D200G	probably benign	Het
Kcnq1	T	C	7: 142,748,083 (GRCm39)		probably null	Het
Kctd9	C	T	14: 67,966,805 (GRCm39)	T106I	probably damaging	Het
Kmt5b	T	A	19: 3,852,240 (GRCm39)	H159Q	probably damaging	Het
Kprp	C	T	3: 92,731,829 (GRCm39)	R407Q	unknown	Het
Kras	T	C	6: 145,177,879 (GRCm39)	Q131R	probably benign	Het
Krt16	T	A	11: 100,138,457 (GRCm39)	R230S	probably damaging	Het
Lpar6	G	A	14: 73,476,147 (GRCm39)	C36Y	probably damaging	Het
Lrp10	T	C	14: 54,707,067 (GRCm39)	S635P	probably benign	Het
Mapre2	C	A	18: 23,991,190 (GRCm39)	H153N	possibly damaging	Het
Mark3	C	A	12: 111,621,762 (GRCm39)	R703S	probably damaging	Het
Mboat2	A	G	12: 25,009,065 (GRCm39)	D457G	probably benign	Het
Med13	T	C	11: 86,210,675 (GRCm39)	D489G	probably benign	Het
Msh2	C	A	17: 88,030,841 (GRCm39)	A906E	probably benign	Het
Mtus1	T	C	8: 41,536,229 (GRCm39)	T496A	probably benign	Het
Nckap5	T	C	1: 125,961,697 (GRCm39)	H204R	probably benign	Het
Nlrc4	G	T	17: 74,753,712 (GRCm39)	P224T	possibly damaging	Het
Oprl1	T	A	2: 181,360,403 (GRCm39)	I153N	probably damaging	Het
Or13a27	A	T	7: 139,925,236 (GRCm39)	I222N	probably damaging	Het
Or4c116	A	T	2: 88,942,140 (GRCm39)		probably null	Het
Or5an1	T	C	19: 12,260,670 (GRCm39)	L86P	possibly damaging	Het
Or5b121	T	A	19: 13,507,442 (GRCm39)	M135K	probably damaging	Het
Otud4	G	A	8: 80,382,318 (GRCm39)	V176I	probably damaging	Het
Pcdhb5	T	C	18: 37,453,943 (GRCm39)	F108L	probably benign	Het
Pde8b	T	C	13: 95,223,250 (GRCm39)	I335V	probably benign	Het
Pdzd7	T	A	19: 45,016,868 (GRCm39)	I886L	possibly damaging	Het
Prune2	C	T	19: 16,980,995 (GRCm39)	P51S	probably damaging	Het
Ptpre	C	T	7: 135,270,861 (GRCm39)	H346Y	probably benign	Het
Pwwp3a	T	C	10: 80,068,702 (GRCm39)	L282P	probably benign	Het
Rab27b	T	C	18: 70,122,659 (GRCm39)	D100G	probably damaging	Het
Rpf1	A	G	3: 146,212,293 (GRCm39)	L349S	probably damaging	Het
Samd14	T	C	11: 94,912,409 (GRCm39)	S233P	probably damaging	Het
Sema6a	C	A	18: 47,433,195 (GRCm39)	V79F	probably damaging	Het
Setbp1	A	G	18: 78,900,697 (GRCm39)	I990T	probably damaging	Het
Setx	A	G	2: 29,070,093 (GRCm39)	R2633G	probably benign	Het
Siae	T	G	9: 37,557,816 (GRCm39)	I541S	possibly damaging	Het
Slc13a1	A	G	6: 24,103,428 (GRCm39)	S372P	possibly damaging	Het
Smarcc2	T	C	10: 128,297,342 (GRCm39)		probably null	Het
Snrpf	T	C	10: 93,423,985 (GRCm39)	S2G	probably benign	Het
Speer2	C	A	16: 69,655,708 (GRCm39)	K39N	probably null	Het
Spink5	T	G	18: 44,119,490 (GRCm39)	F267C	probably damaging	Het
Tgfbrap1	G	T	1: 43,114,666 (GRCm39)	R145S	probably damaging	Het
Tmem161b	C	A	13: 84,442,887 (GRCm39)	T269K	possibly damaging	Het
Tmem64	T	C	4: 15,281,119 (GRCm39)	I304T	probably damaging	Het
Tomm7	A	G	5: 24,049,004 (GRCm39)	I23T	probably benign	Het
Top6bl	T	A	19: 4,708,449 (GRCm39)	S194C	probably damaging	Het
Ttn	A	T	2: 76,641,587 (GRCm39)	L5176Q	possibly damaging	Het
Ttr	C	T	18: 20,803,167 (GRCm39)	A111V	possibly damaging	Het
Usp47	T	A	7: 111,683,089 (GRCm39)	Y561N	probably damaging	Het
Vmn1r17	A	G	6: 57,337,828 (GRCm39)	V130A	probably benign	Het
Wdr45b	A	G	11: 121,219,621 (GRCm39)	I309T	probably benign	Het
Wnt6	T	C	1: 74,823,755 (GRCm39)	L364P	probably damaging	Het
Zc3h13	T	C	14: 75,573,449 (GRCm39)	L1530P	probably damaging	Het
Zfp933	A	G	4: 147,911,321 (GRCm39)	W60R	probably benign	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,743,139 (GRCm39)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,744,083 (GRCm39)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,788,019 (GRCm39)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,792,821 (GRCm39)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	59,836,527 (GRCm39)	missense	unknown
IGL01348:Baz2b	APN	2	59,764,031 (GRCm39)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,799,233 (GRCm39)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,765,615 (GRCm39)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,798,984 (GRCm39)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,792,571 (GRCm39)	missense	probably benign
IGL02370:Baz2b	APN	2	59,753,933 (GRCm39)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,790,407 (GRCm39)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,731,840 (GRCm39)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,747,713 (GRCm39)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,778,604 (GRCm39)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,747,849 (GRCm39)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,792,868 (GRCm39)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,807,718 (GRCm39)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,799,002 (GRCm39)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,807,872 (GRCm39)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,788,087 (GRCm39)	splice site	probably null
IGL02892:Baz2b	APN	2	59,731,080 (GRCm39)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,738,097 (GRCm39)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,733,640 (GRCm39)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,731,898 (GRCm39)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,743,963 (GRCm39)	splice site	probably null
R0136:Baz2b	UTSW	2	59,732,298 (GRCm39)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,737,839 (GRCm39)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,799,721 (GRCm39)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,732,340 (GRCm39)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,767,083 (GRCm39)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,792,826 (GRCm39)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,752,553 (GRCm39)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,792,670 (GRCm39)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,778,598 (GRCm39)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,798,981 (GRCm39)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	59,836,474 (GRCm39)	missense	unknown
R1641:Baz2b	UTSW	2	59,743,234 (GRCm39)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,743,336 (GRCm39)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	59,836,480 (GRCm39)	missense	unknown
R1826:Baz2b	UTSW	2	59,799,077 (GRCm39)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,732,163 (GRCm39)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,799,087 (GRCm39)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,754,024 (GRCm39)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,743,067 (GRCm39)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,743,348 (GRCm39)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,755,010 (GRCm39)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,799,240 (GRCm39)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,742,917 (GRCm39)	splice site	probably null
R4182:Baz2b	UTSW	2	59,928,801 (GRCm39)	intron	probably benign
R4255:Baz2b	UTSW	2	59,750,916 (GRCm39)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,731,957 (GRCm39)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,799,599 (GRCm39)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,788,795 (GRCm39)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,738,087 (GRCm39)	missense	probably benign
R4868:Baz2b	UTSW	2	59,755,226 (GRCm39)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,773,103 (GRCm39)	splice site	probably null
R4889:Baz2b	UTSW	2	59,767,070 (GRCm39)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,756,383 (GRCm39)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	59,928,988 (GRCm39)	intron	probably benign
R5031:Baz2b	UTSW	2	59,743,151 (GRCm39)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,731,835 (GRCm39)	nonsense	probably null
R5276:Baz2b	UTSW	2	59,792,958 (GRCm39)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,762,496 (GRCm39)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,808,946 (GRCm39)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,744,332 (GRCm39)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,790,233 (GRCm39)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,807,770 (GRCm39)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,742,871 (GRCm39)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,809,019 (GRCm39)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,755,150 (GRCm39)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,778,567 (GRCm39)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,737,292 (GRCm39)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,732,073 (GRCm39)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,799,623 (GRCm39)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,755,234 (GRCm39)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,792,776 (GRCm39)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,731,874 (GRCm39)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,743,283 (GRCm39)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,799,120 (GRCm39)	missense	probably benign
R6978:Baz2b	UTSW	2	59,738,059 (GRCm39)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,764,014 (GRCm39)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,792,528 (GRCm39)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,742,841 (GRCm39)	missense
R7198:Baz2b	UTSW	2	59,792,550 (GRCm39)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,792,836 (GRCm39)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,750,781 (GRCm39)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,807,792 (GRCm39)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,792,817 (GRCm39)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,792,485 (GRCm39)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,731,112 (GRCm39)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,792,580 (GRCm39)	missense	probably benign
R8343:Baz2b	UTSW	2	59,731,858 (GRCm39)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8438:Baz2b	UTSW	2	59,747,828 (GRCm39)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8511:Baz2b	UTSW	2	59,732,158 (GRCm39)	missense	probably benign
R8893:Baz2b	UTSW	2	59,755,149 (GRCm39)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,778,583 (GRCm39)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,799,608 (GRCm39)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,743,993 (GRCm39)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,743,331 (GRCm39)	missense	probably benign
R9577:Baz2b	UTSW	2	59,809,031 (GRCm39)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,799,300 (GRCm39)	missense	probably benign
R9601:Baz2b	UTSW	2	59,731,847 (GRCm39)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,731,824 (GRCm39)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,731,828 (GRCm39)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,807,705 (GRCm39)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,731,019 (GRCm39)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,799,626 (GRCm39)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,790,359 (GRCm39)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,807,864 (GRCm39)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,807,749 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GTCACTAATGCCAGGGGAAC -3'
(R):5'- TGTCAATCTGAGCACGAGTGG -3'

Sequencing Primer
(F):5'- GTAAGAAATCAGTGAGTGGC -3'
(R):5'- GGGTCAGCAATGACGCAACC -3'

Posted On

2016-06-21