Incidental Mutation 'R5134:Tdrd6'
| ID |
396086 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tdrd6
|
| Ensembl Gene |
ENSMUSG00000040140 |
| Gene Name |
tudor domain containing 6 |
| Synonyms |
|
| MMRRC Submission |
042722-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5134 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
43926226-43941190 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 43937101 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 1316
(Y1316H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131277
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045717]
[ENSMUST00000168073]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000045717
AA Change: Y1316H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000035338
Gene: ENSMUSG00000040140
AA Change: Y1316H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
14 |
133 |
9.9e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2026 |
2083 |
9.45e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000168073
AA Change: Y1316H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131277
Gene: ENSMUSG00000040140
AA Change: Y1316H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
12 |
133 |
7.2e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2027 |
2084 |
9.45e-1 |
SMART |
|
| Meta Mutation Damage Score |
0.4434 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.5%
|
| Validation Efficiency |
96% (100/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit male fertility associated with arrested spermatogenesis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adarb1 |
T |
A |
10: 77,161,679 (GRCm39) |
|
probably benign |
Het |
| Adrb3 |
A |
C |
8: 27,717,798 (GRCm39) |
M217R |
probably damaging |
Het |
| Ank2 |
A |
T |
3: 126,757,094 (GRCm39) |
N1054K |
possibly damaging |
Het |
| Aox4 |
A |
T |
1: 58,275,835 (GRCm39) |
D389V |
probably benign |
Het |
| Aph1a |
G |
T |
3: 95,802,843 (GRCm39) |
G148W |
probably damaging |
Het |
| Arsj |
A |
G |
3: 126,231,803 (GRCm39) |
D183G |
probably benign |
Het |
| Atg2b |
A |
G |
12: 105,641,209 (GRCm39) |
S76P |
probably damaging |
Het |
| Atxn7l1 |
C |
A |
12: 33,422,875 (GRCm39) |
N815K |
probably damaging |
Het |
| Cd3d |
A |
T |
9: 44,896,296 (GRCm39) |
E28D |
probably damaging |
Het |
| Cir1 |
G |
A |
2: 73,114,847 (GRCm39) |
R404* |
probably null |
Het |
| Cops8 |
A |
G |
1: 90,538,724 (GRCm39) |
D51G |
probably damaging |
Het |
| Csgalnact1 |
T |
C |
8: 68,913,623 (GRCm39) |
E194G |
probably benign |
Het |
| Cstf2t |
T |
A |
19: 31,061,494 (GRCm39) |
D343E |
probably damaging |
Het |
| Ddx23 |
A |
T |
15: 98,548,651 (GRCm39) |
D352E |
possibly damaging |
Het |
| Dhx34 |
G |
T |
7: 15,952,175 (GRCm39) |
A150D |
possibly damaging |
Het |
| Dnal4 |
A |
T |
15: 79,647,766 (GRCm39) |
V32E |
possibly damaging |
Het |
| Dvl3 |
G |
T |
16: 20,343,357 (GRCm39) |
|
probably benign |
Het |
| Ehmt1 |
G |
T |
2: 24,767,509 (GRCm39) |
P135T |
probably damaging |
Het |
| Enpp2 |
C |
T |
15: 54,762,726 (GRCm39) |
R174H |
probably damaging |
Het |
| Eps15 |
G |
A |
4: 109,223,727 (GRCm39) |
|
probably benign |
Het |
| F10 |
T |
C |
8: 13,105,698 (GRCm39) |
V421A |
probably damaging |
Het |
| Fabp3 |
C |
T |
4: 130,206,180 (GRCm39) |
T57I |
probably benign |
Het |
| Fer1l6 |
A |
T |
15: 58,512,003 (GRCm39) |
D1490V |
probably damaging |
Het |
| Fsd1l |
A |
G |
4: 53,647,766 (GRCm39) |
K70E |
probably benign |
Het |
| Galnt12 |
G |
A |
4: 47,113,818 (GRCm39) |
A79T |
probably damaging |
Het |
| Galnt17 |
A |
T |
5: 130,992,873 (GRCm39) |
M347K |
probably damaging |
Het |
| Glyatl3 |
A |
G |
17: 41,215,921 (GRCm39) |
V195A |
probably benign |
Het |
| Gm10770 |
A |
T |
2: 150,021,480 (GRCm39) |
|
probably null |
Het |
| Gm5578 |
A |
T |
6: 112,583,046 (GRCm39) |
|
noncoding transcript |
Het |
| Grn |
C |
A |
11: 102,321,380 (GRCm39) |
|
probably benign |
Het |
| Gsk3b |
G |
A |
16: 38,060,882 (GRCm39) |
R418H |
probably damaging |
Het |
| Hspa12b |
A |
G |
2: 130,981,428 (GRCm39) |
E221G |
possibly damaging |
Het |
| Ighv1-50 |
T |
G |
12: 115,083,653 (GRCm39) |
Q22H |
probably benign |
Het |
| Ipcef1 |
A |
G |
10: 6,869,950 (GRCm39) |
I150T |
probably benign |
Het |
| Ipp |
T |
A |
4: 116,372,654 (GRCm39) |
F228I |
possibly damaging |
Het |
| Itgb7 |
A |
G |
15: 102,125,842 (GRCm39) |
C596R |
probably damaging |
Het |
| Kif27 |
T |
C |
13: 58,438,904 (GRCm39) |
D1219G |
possibly damaging |
Het |
| Lats1 |
T |
A |
10: 7,567,575 (GRCm39) |
D115E |
probably benign |
Het |
| Lpcat3 |
A |
G |
6: 124,679,493 (GRCm39) |
N331S |
probably benign |
Het |
| Lrpprc |
A |
T |
17: 85,058,684 (GRCm39) |
N725K |
probably benign |
Het |
| Lss |
T |
G |
10: 76,382,070 (GRCm39) |
|
probably benign |
Het |
| Mfsd6 |
T |
C |
1: 52,747,515 (GRCm39) |
Y450C |
possibly damaging |
Het |
| Mmp21 |
A |
T |
7: 133,280,742 (GRCm39) |
V76E |
probably benign |
Het |
| Mtmr11 |
A |
T |
3: 96,077,223 (GRCm39) |
Y527F |
probably damaging |
Het |
| Nat10 |
A |
T |
2: 103,573,638 (GRCm39) |
F327I |
probably benign |
Het |
| Nfkbiz |
A |
T |
16: 55,638,863 (GRCm39) |
M199K |
probably damaging |
Het |
| Nuak1 |
A |
G |
10: 84,210,214 (GRCm39) |
Y625H |
probably benign |
Het |
| Odf1 |
A |
G |
15: 38,226,393 (GRCm39) |
T98A |
possibly damaging |
Het |
| Oprl1 |
T |
A |
2: 181,360,403 (GRCm39) |
I153N |
probably damaging |
Het |
| Or10g3b |
T |
C |
14: 52,587,248 (GRCm39) |
N85S |
probably benign |
Het |
| Or1j4 |
A |
T |
2: 36,740,488 (GRCm39) |
L143F |
probably benign |
Het |
| Or4x13 |
T |
A |
2: 90,231,107 (GRCm39) |
M34K |
probably benign |
Het |
| Osbpl8 |
T |
A |
10: 111,124,554 (GRCm39) |
D705E |
probably benign |
Het |
| Otud4 |
G |
A |
8: 80,382,318 (GRCm39) |
V176I |
probably damaging |
Het |
| Paics |
T |
C |
5: 77,104,669 (GRCm39) |
|
probably benign |
Het |
| Pax5 |
A |
G |
4: 44,710,407 (GRCm39) |
M1T |
probably null |
Het |
| Pck1 |
A |
T |
2: 172,995,282 (GRCm39) |
N34I |
probably benign |
Het |
| Pde8b |
T |
C |
13: 95,223,250 (GRCm39) |
I335V |
probably benign |
Het |
| Piezo2 |
A |
G |
18: 63,207,691 (GRCm39) |
V1440A |
probably damaging |
Het |
| Prr23a4 |
T |
C |
9: 98,785,793 (GRCm39) |
S153P |
probably benign |
Het |
| Ptpre |
T |
A |
7: 135,253,821 (GRCm39) |
F83Y |
probably damaging |
Het |
| Pwwp3a |
T |
C |
10: 80,068,702 (GRCm39) |
L282P |
probably benign |
Het |
| Rassf6 |
T |
A |
5: 90,752,225 (GRCm39) |
|
probably null |
Het |
| Rilp |
A |
T |
11: 75,403,534 (GRCm39) |
L325F |
probably damaging |
Het |
| Rpf1 |
A |
G |
3: 146,212,293 (GRCm39) |
L349S |
probably damaging |
Het |
| Rprd2 |
G |
C |
3: 95,672,632 (GRCm39) |
R924G |
probably benign |
Het |
| Rps6kc1 |
T |
A |
1: 190,505,845 (GRCm39) |
D1039V |
probably damaging |
Het |
| Rufy3 |
G |
A |
5: 88,793,426 (GRCm39) |
V579I |
probably benign |
Het |
| Serpinc1 |
A |
G |
1: 160,825,140 (GRCm39) |
|
probably null |
Het |
| Siae |
T |
G |
9: 37,557,816 (GRCm39) |
I541S |
possibly damaging |
Het |
| St14 |
T |
G |
9: 31,006,879 (GRCm39) |
D649A |
probably benign |
Het |
| Stab2 |
A |
G |
10: 86,707,674 (GRCm39) |
|
probably null |
Het |
| Sun3 |
T |
C |
11: 8,988,287 (GRCm39) |
T12A |
probably benign |
Het |
| Thbs3 |
CAGAAG |
CAG |
3: 89,130,409 (GRCm39) |
|
probably benign |
Het |
| Tmem161b |
C |
A |
13: 84,442,887 (GRCm39) |
T269K |
possibly damaging |
Het |
| Trav14-3 |
T |
A |
14: 54,000,701 (GRCm39) |
S17T |
unknown |
Het |
| Trmu |
T |
A |
15: 85,780,556 (GRCm39) |
|
probably null |
Het |
| Ttn |
T |
A |
2: 76,537,586 (GRCm39) |
T26454S |
possibly damaging |
Het |
| Ubr3 |
T |
C |
2: 69,850,790 (GRCm39) |
|
probably benign |
Het |
| Unc5b |
A |
T |
10: 60,610,879 (GRCm39) |
V376E |
probably benign |
Het |
| Usp3 |
T |
C |
9: 66,449,814 (GRCm39) |
S166G |
possibly damaging |
Het |
| Vldlr |
C |
A |
19: 27,216,212 (GRCm39) |
C344* |
probably null |
Het |
| Vmn1r17 |
A |
G |
6: 57,337,828 (GRCm39) |
V130A |
probably benign |
Het |
| Wdfy3 |
A |
C |
5: 102,091,969 (GRCm39) |
Y457D |
probably damaging |
Het |
| Zbtb2 |
T |
C |
10: 4,319,267 (GRCm39) |
Y253C |
possibly damaging |
Het |
| Zfp687 |
A |
C |
3: 94,917,697 (GRCm39) |
F692V |
probably damaging |
Het |
| Zfp758 |
A |
G |
17: 22,594,386 (GRCm39) |
K291E |
probably damaging |
Het |
| Zfp799 |
A |
T |
17: 33,039,415 (GRCm39) |
C284S |
probably damaging |
Het |
| Zp1 |
C |
A |
19: 10,897,926 (GRCm39) |
C5F |
probably benign |
Het |
|
| Other mutations in Tdrd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00571:Tdrd6
|
APN |
17 |
43,939,051 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00844:Tdrd6
|
APN |
17 |
43,928,087 (GRCm39) |
missense |
probably benign |
|
|
IGL00845:Tdrd6
|
APN |
17 |
43,937,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,936,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,935,657 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01575:Tdrd6
|
APN |
17 |
43,938,871 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01812:Tdrd6
|
APN |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02013:Tdrd6
|
APN |
17 |
43,936,837 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02067:Tdrd6
|
APN |
17 |
43,939,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02112:Tdrd6
|
APN |
17 |
43,940,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02159:Tdrd6
|
APN |
17 |
43,939,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02226:Tdrd6
|
APN |
17 |
43,938,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02416:Tdrd6
|
APN |
17 |
43,935,629 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02577:Tdrd6
|
APN |
17 |
43,937,728 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02631:Tdrd6
|
APN |
17 |
43,937,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02738:Tdrd6
|
APN |
17 |
43,931,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02792:Tdrd6
|
APN |
17 |
43,935,918 (GRCm39) |
missense |
probably benign |
|
|
IGL02929:Tdrd6
|
APN |
17 |
43,940,604 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02934:Tdrd6
|
APN |
17 |
43,938,778 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02954:Tdrd6
|
APN |
17 |
43,938,153 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02969:Tdrd6
|
APN |
17 |
43,938,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03006:Tdrd6
|
APN |
17 |
43,936,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03155:Tdrd6
|
APN |
17 |
43,936,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03219:Tdrd6
|
APN |
17 |
43,938,855 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03372:Tdrd6
|
APN |
17 |
43,936,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Edward
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
eliza
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
Elizabeth
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
henry
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
BB001:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
BB011:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
G1citation:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0030:Tdrd6
|
UTSW |
17 |
43,937,482 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0057:Tdrd6
|
UTSW |
17 |
43,928,052 (GRCm39) |
splice site |
probably benign |
|
|
R0090:Tdrd6
|
UTSW |
17 |
43,939,132 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Tdrd6
|
UTSW |
17 |
43,935,199 (GRCm39) |
missense |
probably benign |
|
|
R0463:Tdrd6
|
UTSW |
17 |
43,936,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Tdrd6
|
UTSW |
17 |
43,940,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0650:Tdrd6
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1226:Tdrd6
|
UTSW |
17 |
43,937,523 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1309:Tdrd6
|
UTSW |
17 |
43,937,512 (GRCm39) |
missense |
probably benign |
|
|
R1483:Tdrd6
|
UTSW |
17 |
43,938,498 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1561:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1574:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1647:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1648:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1723:Tdrd6
|
UTSW |
17 |
43,939,218 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1786:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1819:Tdrd6
|
UTSW |
17 |
43,937,442 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1836:Tdrd6
|
UTSW |
17 |
43,936,480 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1892:Tdrd6
|
UTSW |
17 |
43,935,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1911:Tdrd6
|
UTSW |
17 |
43,937,979 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1936:Tdrd6
|
UTSW |
17 |
43,937,358 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2005:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2006:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2133:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3010:Tdrd6
|
UTSW |
17 |
43,938,933 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4225:Tdrd6
|
UTSW |
17 |
43,936,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4449:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4531:Tdrd6
|
UTSW |
17 |
43,939,645 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4624:Tdrd6
|
UTSW |
17 |
43,936,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4665:Tdrd6
|
UTSW |
17 |
43,935,007 (GRCm39) |
missense |
probably benign |
|
|
R4676:Tdrd6
|
UTSW |
17 |
43,938,501 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4785:Tdrd6
|
UTSW |
17 |
43,936,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4912:Tdrd6
|
UTSW |
17 |
43,935,218 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5145:Tdrd6
|
UTSW |
17 |
43,936,966 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5623:Tdrd6
|
UTSW |
17 |
43,940,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5712:Tdrd6
|
UTSW |
17 |
43,937,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Tdrd6
|
UTSW |
17 |
43,935,768 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5913:Tdrd6
|
UTSW |
17 |
43,939,302 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6142:Tdrd6
|
UTSW |
17 |
43,940,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6181:Tdrd6
|
UTSW |
17 |
43,939,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6195:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6289:Tdrd6
|
UTSW |
17 |
43,935,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6315:Tdrd6
|
UTSW |
17 |
43,937,229 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6578:Tdrd6
|
UTSW |
17 |
43,939,852 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6645:Tdrd6
|
UTSW |
17 |
43,935,423 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6822:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7000:Tdrd6
|
UTSW |
17 |
43,938,599 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7075:Tdrd6
|
UTSW |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7107:Tdrd6
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7381:Tdrd6
|
UTSW |
17 |
43,936,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7458:Tdrd6
|
UTSW |
17 |
43,935,937 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7461:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7505:Tdrd6
|
UTSW |
17 |
43,938,570 (GRCm39) |
missense |
not run |
|
|
R7583:Tdrd6
|
UTSW |
17 |
43,935,129 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7613:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7723:Tdrd6
|
UTSW |
17 |
43,936,851 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7759:Tdrd6
|
UTSW |
17 |
43,935,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7924:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8002:Tdrd6
|
UTSW |
17 |
43,940,710 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8134:Tdrd6
|
UTSW |
17 |
43,937,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8231:Tdrd6
|
UTSW |
17 |
43,933,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8242:Tdrd6
|
UTSW |
17 |
43,939,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8542:Tdrd6
|
UTSW |
17 |
43,935,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8713:Tdrd6
|
UTSW |
17 |
43,935,910 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9100:Tdrd6
|
UTSW |
17 |
43,936,305 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9201:Tdrd6
|
UTSW |
17 |
43,936,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9222:Tdrd6
|
UTSW |
17 |
43,939,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9369:Tdrd6
|
UTSW |
17 |
43,936,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9373:Tdrd6
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9384:Tdrd6
|
UTSW |
17 |
43,937,783 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9448:Tdrd6
|
UTSW |
17 |
43,936,567 (GRCm39) |
missense |
probably benign |
|
|
R9534:Tdrd6
|
UTSW |
17 |
43,936,510 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9613:Tdrd6
|
UTSW |
17 |
43,939,518 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,884 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,044 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1088:Tdrd6
|
UTSW |
17 |
43,937,409 (GRCm39) |
missense |
probably benign |
0.23 |
|
Z1177:Tdrd6
|
UTSW |
17 |
43,938,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGCTCGGTACCATAAGTTATCCTC -3'
(R):5'- ATCAGGACTCAGTGGGCAAC -3'
Sequencing Primer
(F):5'- TTATCCTCTGGGAAAACGGC -3'
(R):5'- CAACAAAAATGATGGAGGGTTTCC -3'
|
| Posted On |
2016-06-21 |
Incidental Mutation