Incidental Mutation 'R5135:Pex5l'
| ID |
396104 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pex5l
|
| Ensembl Gene |
ENSMUSG00000027674 |
| Gene Name |
peroxisomal biogenesis factor 5-like |
| Synonyms |
PXR2, TRIP8b, Pex2, 1700016J08Rik |
| MMRRC Submission |
043261-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.604)
|
| Stock # |
R5135 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
33003557-33197396 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 33009980 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Glutamic Acid
at position 386
(A386E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142196
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078226]
[ENSMUST00000108221]
[ENSMUST00000108224]
[ENSMUST00000108225]
[ENSMUST00000108226]
[ENSMUST00000192093]
[ENSMUST00000193289]
[ENSMUST00000193681]
[ENSMUST00000194016]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000078226
AA Change: A351E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000077353
Gene: ENSMUSG00000027674
AA Change: A351E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
113 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
228 |
N/A |
INTRINSIC |
|
TPR
|
349 |
382 |
6.95e-4 |
SMART |
|
Blast:TPR
|
383 |
416 |
4e-14 |
BLAST |
|
TPR
|
463 |
496 |
3.19e-3 |
SMART |
|
TPR
|
497 |
530 |
3.47e-4 |
SMART |
|
TPR
|
531 |
564 |
1.1e-1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000108219
|
| SMART Domains |
Protein: ENSMUSP00000103854
Gene: ENSMUSG00000027674
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
124 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
240 |
N/A |
INTRINSIC |
|
PDB:4EQF|A
|
266 |
362 |
8e-64 |
PDB |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108221
AA Change: A80E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103856
Gene: ENSMUSG00000027674
AA Change: A80E
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
78 |
111 |
6.95e-4 |
SMART |
|
Blast:TPR
|
112 |
145 |
2e-14 |
BLAST |
|
TPR
|
192 |
225 |
3.19e-3 |
SMART |
|
TPR
|
226 |
259 |
3.47e-4 |
SMART |
|
TPR
|
260 |
293 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108224
AA Change: A327E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103859
Gene: ENSMUSG00000027674
AA Change: A327E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
88 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
190 |
204 |
N/A |
INTRINSIC |
|
TPR
|
325 |
358 |
6.95e-4 |
SMART |
|
Blast:TPR
|
359 |
392 |
2e-14 |
BLAST |
|
TPR
|
439 |
472 |
3.19e-3 |
SMART |
|
TPR
|
473 |
506 |
3.47e-4 |
SMART |
|
TPR
|
507 |
540 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108225
AA Change: A351E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103860
Gene: ENSMUSG00000027674
AA Change: A351E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
113 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
228 |
N/A |
INTRINSIC |
|
TPR
|
349 |
382 |
6.95e-4 |
SMART |
|
Blast:TPR
|
383 |
416 |
4e-14 |
BLAST |
|
TPR
|
463 |
496 |
3.19e-3 |
SMART |
|
TPR
|
497 |
530 |
3.47e-4 |
SMART |
|
TPR
|
531 |
564 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108226
AA Change: A303E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103861
Gene: ENSMUSG00000027674
AA Change: A303E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
65 |
81 |
N/A |
INTRINSIC |
|
low complexity region
|
166 |
180 |
N/A |
INTRINSIC |
|
TPR
|
301 |
334 |
6.95e-4 |
SMART |
|
Blast:TPR
|
335 |
368 |
2e-14 |
BLAST |
|
TPR
|
415 |
448 |
3.19e-3 |
SMART |
|
TPR
|
449 |
482 |
3.47e-4 |
SMART |
|
TPR
|
483 |
516 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000192093
AA Change: A351E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000141387
Gene: ENSMUSG00000027674
AA Change: A351E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
113 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
228 |
N/A |
INTRINSIC |
|
TPR
|
349 |
382 |
6.95e-4 |
SMART |
|
Blast:TPR
|
383 |
416 |
4e-14 |
BLAST |
|
TPR
|
463 |
496 |
3.19e-3 |
SMART |
|
TPR
|
497 |
530 |
3.47e-4 |
SMART |
|
TPR
|
531 |
564 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000193289
AA Change: A386E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142008
Gene: ENSMUSG00000027674
AA Change: A386E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
148 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
263 |
N/A |
INTRINSIC |
|
TPR
|
384 |
417 |
6.95e-4 |
SMART |
|
Blast:TPR
|
418 |
451 |
4e-14 |
BLAST |
|
TPR
|
498 |
531 |
3.19e-3 |
SMART |
|
TPR
|
532 |
565 |
3.47e-4 |
SMART |
|
TPR
|
566 |
599 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000193681
AA Change: A386E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000141454
Gene: ENSMUSG00000027674
AA Change: A386E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
148 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
263 |
N/A |
INTRINSIC |
|
TPR
|
384 |
417 |
6.95e-4 |
SMART |
|
Blast:TPR
|
418 |
451 |
4e-14 |
BLAST |
|
TPR
|
498 |
531 |
3.19e-3 |
SMART |
|
TPR
|
532 |
565 |
3.47e-4 |
SMART |
|
TPR
|
566 |
599 |
1.1e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000194016
AA Change: A386E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142196
Gene: ENSMUSG00000027674
AA Change: A386E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
148 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
263 |
N/A |
INTRINSIC |
|
TPR
|
384 |
417 |
6.95e-4 |
SMART |
|
Blast:TPR
|
418 |
451 |
4e-14 |
BLAST |
|
TPR
|
498 |
531 |
3.19e-3 |
SMART |
|
TPR
|
532 |
565 |
3.47e-4 |
SMART |
|
TPR
|
566 |
599 |
1.1e-1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192259
|
| Meta Mutation Damage Score |
0.8031 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
98% (82/84) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a targeted mutation lacking isoform b exhibit exhibit reduced hyperpolarization-activated current in CA1 pyramidal neuron, impaired motor learning, impaired nest-building, decreased startle reflex, and decreased depression-related behaviors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700056E22Rik |
T |
C |
1: 183,765,703 (GRCm39) |
S119G |
probably benign |
Het |
| 4930553M12Rik |
G |
T |
4: 88,786,508 (GRCm39) |
H37N |
unknown |
Het |
| Adam10 |
T |
A |
9: 70,673,356 (GRCm39) |
C496S |
probably damaging |
Het |
| Aldh18a1 |
A |
C |
19: 40,543,261 (GRCm39) |
|
probably benign |
Het |
| Alox5 |
A |
G |
6: 116,390,747 (GRCm39) |
F468S |
probably benign |
Het |
| Ankrd50 |
T |
C |
3: 38,509,952 (GRCm39) |
H805R |
probably damaging |
Het |
| Ap2s1 |
T |
A |
7: 16,481,248 (GRCm39) |
D72E |
probably damaging |
Het |
| Apaf1 |
T |
C |
10: 90,895,956 (GRCm39) |
Y372C |
probably damaging |
Het |
| Apob |
C |
T |
12: 8,060,086 (GRCm39) |
T2823I |
probably damaging |
Het |
| Bhmt |
A |
G |
13: 93,763,831 (GRCm39) |
V70A |
probably damaging |
Het |
| Bltp3b |
T |
C |
10: 89,625,217 (GRCm39) |
I48T |
probably damaging |
Het |
| Cdc42bpg |
T |
A |
19: 6,370,648 (GRCm39) |
L1247H |
probably damaging |
Het |
| Cel |
A |
G |
2: 28,449,435 (GRCm39) |
V264A |
probably benign |
Het |
| Celsr2 |
T |
C |
3: 108,305,975 (GRCm39) |
N2043S |
probably damaging |
Het |
| Clca4a |
A |
T |
3: 144,660,707 (GRCm39) |
W706R |
probably damaging |
Het |
| Col22a1 |
G |
T |
15: 71,671,186 (GRCm39) |
P1058Q |
unknown |
Het |
| Cyp4a14 |
A |
G |
4: 115,347,157 (GRCm39) |
|
probably null |
Het |
| Dhx30 |
T |
G |
9: 109,927,863 (GRCm39) |
R55S |
probably damaging |
Het |
| Dlgap5 |
C |
T |
14: 47,637,122 (GRCm39) |
R452H |
probably damaging |
Het |
| Dnah12 |
T |
A |
14: 26,492,434 (GRCm39) |
D1191E |
probably damaging |
Het |
| Dock3 |
A |
T |
9: 106,810,196 (GRCm39) |
I164N |
probably damaging |
Het |
| Edrf1 |
T |
A |
7: 133,252,773 (GRCm39) |
M436K |
probably benign |
Het |
| Eif2ak2 |
T |
A |
17: 79,173,774 (GRCm39) |
Y268F |
probably damaging |
Het |
| Evi2a |
G |
A |
11: 79,418,277 (GRCm39) |
T111M |
possibly damaging |
Het |
| Fzd4 |
A |
G |
7: 89,056,709 (GRCm39) |
E252G |
probably damaging |
Het |
| Gcm2 |
A |
G |
13: 41,256,435 (GRCm39) |
V438A |
probably benign |
Het |
| Gm10722 |
T |
C |
9: 3,000,937 (GRCm39) |
C6R |
probably benign |
Het |
| Gm4787 |
G |
C |
12: 81,424,604 (GRCm39) |
T518S |
probably benign |
Het |
| Gm4846 |
T |
C |
1: 166,311,551 (GRCm39) |
D436G |
probably damaging |
Het |
| Gm5414 |
T |
A |
15: 101,536,203 (GRCm39) |
I141F |
probably damaging |
Het |
| Gm6185 |
T |
A |
1: 161,025,801 (GRCm39) |
|
noncoding transcript |
Het |
| Grip2 |
T |
C |
6: 91,750,897 (GRCm39) |
E776G |
possibly damaging |
Het |
| H2-Ob |
T |
A |
17: 34,462,490 (GRCm39) |
V160E |
probably benign |
Het |
| Hormad1 |
T |
C |
3: 95,492,531 (GRCm39) |
|
probably benign |
Het |
| Ighv2-1 |
A |
T |
12: 113,538,082 (GRCm39) |
|
probably benign |
Het |
| Igkv4-92 |
A |
T |
6: 68,732,538 (GRCm39) |
C14S |
probably benign |
Het |
| Iqsec3 |
T |
C |
6: 121,360,878 (GRCm39) |
I993M |
probably damaging |
Het |
| Kdm5b |
T |
A |
1: 134,516,484 (GRCm39) |
|
probably benign |
Het |
| Kitl |
T |
C |
10: 99,924,084 (GRCm39) |
|
probably null |
Het |
| Klhl26 |
G |
T |
8: 70,905,368 (GRCm39) |
R100S |
probably benign |
Het |
| Kpna4 |
C |
T |
3: 69,000,142 (GRCm39) |
|
probably null |
Het |
| Lama5 |
T |
A |
2: 179,844,013 (GRCm39) |
N383Y |
possibly damaging |
Het |
| Large1 |
T |
G |
8: 73,544,724 (GRCm39) |
I685L |
probably benign |
Het |
| Larp4b |
A |
G |
13: 9,220,773 (GRCm39) |
E590G |
probably damaging |
Het |
| Liph |
A |
T |
16: 21,774,915 (GRCm39) |
C425* |
probably null |
Het |
| Lrrc31 |
A |
T |
3: 30,739,039 (GRCm39) |
C327* |
probably null |
Het |
| Lrrc36 |
T |
C |
8: 106,190,530 (GRCm39) |
V733A |
probably benign |
Het |
| Mmel1 |
T |
A |
4: 154,966,781 (GRCm39) |
I83K |
probably benign |
Het |
| Myo16 |
G |
T |
8: 10,526,114 (GRCm39) |
V885L |
probably benign |
Het |
| Naip2 |
A |
T |
13: 100,315,948 (GRCm39) |
N277K |
probably damaging |
Het |
| Ncapg2 |
T |
A |
12: 116,391,406 (GRCm39) |
I485N |
possibly damaging |
Het |
| Npc1l1 |
A |
T |
11: 6,174,245 (GRCm39) |
Y687N |
possibly damaging |
Het |
| Obscn |
A |
T |
11: 59,020,479 (GRCm39) |
V922E |
probably damaging |
Het |
| Oc90 |
A |
G |
15: 65,755,679 (GRCm39) |
S223P |
probably benign |
Het |
| Or1e16 |
AGCGGTCGTAGGC |
AGC |
11: 73,286,480 (GRCm39) |
|
probably null |
Het |
| Or4a80 |
A |
T |
2: 89,582,239 (GRCm39) |
L311H |
possibly damaging |
Het |
| Or4e1 |
T |
C |
14: 52,701,311 (GRCm39) |
I52V |
probably benign |
Het |
| Pakap |
G |
T |
4: 57,855,912 (GRCm39) |
A414S |
probably benign |
Het |
| Pdlim5 |
C |
T |
3: 142,010,126 (GRCm39) |
R174H |
probably benign |
Het |
| Plcxd1 |
T |
A |
5: 110,249,229 (GRCm39) |
|
probably benign |
Het |
| Pramel12 |
T |
G |
4: 143,145,579 (GRCm39) |
S349R |
probably benign |
Het |
| Prl8a1 |
A |
T |
13: 27,763,802 (GRCm39) |
|
probably null |
Het |
| Ryr2 |
G |
T |
13: 11,677,016 (GRCm39) |
N3278K |
probably benign |
Het |
| Sacm1l |
A |
G |
9: 123,406,090 (GRCm39) |
M324V |
probably benign |
Het |
| Sdad1 |
T |
C |
5: 92,451,793 (GRCm39) |
T143A |
probably benign |
Het |
| Sec11a |
A |
T |
7: 80,572,812 (GRCm39) |
|
probably benign |
Het |
| Sema6a |
A |
G |
18: 47,424,239 (GRCm39) |
V223A |
probably damaging |
Het |
| Serpinb6c |
A |
G |
13: 34,064,080 (GRCm39) |
V325A |
probably damaging |
Het |
| Slc4a2 |
G |
A |
5: 24,635,125 (GRCm39) |
A177T |
possibly damaging |
Het |
| Slc5a4a |
A |
G |
10: 75,983,428 (GRCm39) |
N22D |
unknown |
Het |
| Stard13 |
C |
T |
5: 150,986,232 (GRCm39) |
W308* |
probably null |
Het |
| Tanc2 |
C |
T |
11: 105,748,379 (GRCm39) |
L504F |
possibly damaging |
Het |
| Tfap2e |
G |
T |
4: 126,614,337 (GRCm39) |
N282K |
probably damaging |
Het |
| Usp36 |
G |
T |
11: 118,155,731 (GRCm39) |
T682K |
possibly damaging |
Het |
| Zc3h11a |
T |
C |
1: 133,561,527 (GRCm39) |
T315A |
probably benign |
Het |
| Zfa-ps |
T |
A |
10: 52,419,118 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp1002 |
A |
T |
2: 150,097,410 (GRCm39) |
Y34* |
probably null |
Het |
| Zfp663 |
A |
T |
2: 165,195,590 (GRCm39) |
C210S |
possibly damaging |
Het |
| Zfp747 |
T |
C |
7: 126,973,566 (GRCm39) |
I201M |
probably damaging |
Het |
| Zic4 |
C |
T |
9: 91,266,205 (GRCm39) |
T276M |
probably damaging |
Het |
|
| Other mutations in Pex5l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01397:Pex5l
|
APN |
3 |
33,006,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01621:Pex5l
|
APN |
3 |
33,069,110 (GRCm39) |
splice site |
probably null |
|
|
IGL01813:Pex5l
|
APN |
3 |
33,136,204 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02313:Pex5l
|
APN |
3 |
33,047,141 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02508:Pex5l
|
APN |
3 |
33,047,051 (GRCm39) |
splice site |
probably benign |
|
|
IGL02997:Pex5l
|
APN |
3 |
33,009,991 (GRCm39) |
splice site |
probably benign |
|
|
R0195:Pex5l
|
UTSW |
3 |
33,047,102 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0674:Pex5l
|
UTSW |
3 |
33,006,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Pex5l
|
UTSW |
3 |
33,008,685 (GRCm39) |
splice site |
probably benign |
|
|
R1500:Pex5l
|
UTSW |
3 |
33,069,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1513:Pex5l
|
UTSW |
3 |
33,069,162 (GRCm39) |
nonsense |
probably null |
|
|
R1695:Pex5l
|
UTSW |
3 |
33,008,531 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1850:Pex5l
|
UTSW |
3 |
33,005,025 (GRCm39) |
splice site |
probably null |
|
|
R2165:Pex5l
|
UTSW |
3 |
33,007,281 (GRCm39) |
splice site |
probably null |
|
|
R2679:Pex5l
|
UTSW |
3 |
33,136,201 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2880:Pex5l
|
UTSW |
3 |
33,047,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2881:Pex5l
|
UTSW |
3 |
33,047,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3766:Pex5l
|
UTSW |
3 |
33,061,327 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3780:Pex5l
|
UTSW |
3 |
33,004,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3934:Pex5l
|
UTSW |
3 |
33,061,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3975:Pex5l
|
UTSW |
3 |
33,069,164 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4285:Pex5l
|
UTSW |
3 |
33,061,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Pex5l
|
UTSW |
3 |
33,047,134 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4855:Pex5l
|
UTSW |
3 |
33,196,989 (GRCm39) |
splice site |
probably benign |
|
|
R4868:Pex5l
|
UTSW |
3 |
33,006,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5217:Pex5l
|
UTSW |
3 |
33,061,477 (GRCm39) |
splice site |
probably null |
|
|
R5223:Pex5l
|
UTSW |
3 |
33,012,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5362:Pex5l
|
UTSW |
3 |
33,047,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5398:Pex5l
|
UTSW |
3 |
33,006,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5829:Pex5l
|
UTSW |
3 |
33,060,139 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6731:Pex5l
|
UTSW |
3 |
33,012,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Pex5l
|
UTSW |
3 |
33,078,840 (GRCm39) |
splice site |
probably null |
|
|
R7452:Pex5l
|
UTSW |
3 |
33,058,467 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7549:Pex5l
|
UTSW |
3 |
33,136,184 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7563:Pex5l
|
UTSW |
3 |
33,008,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7757:Pex5l
|
UTSW |
3 |
33,136,300 (GRCm39) |
start gained |
probably benign |
|
|
R8030:Pex5l
|
UTSW |
3 |
33,008,568 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8143:Pex5l
|
UTSW |
3 |
33,136,658 (GRCm39) |
start gained |
probably benign |
|
|
R8242:Pex5l
|
UTSW |
3 |
33,060,184 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8919:Pex5l
|
UTSW |
3 |
33,007,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9034:Pex5l
|
UTSW |
3 |
33,006,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9422:Pex5l
|
UTSW |
3 |
33,136,401 (GRCm39) |
start gained |
probably benign |
|
|
R9585:Pex5l
|
UTSW |
3 |
33,060,091 (GRCm39) |
missense |
probably benign |
|
|
R9654:Pex5l
|
UTSW |
3 |
33,010,827 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9711:Pex5l
|
UTSW |
3 |
33,136,204 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Pex5l
|
UTSW |
3 |
33,061,308 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGGAAACTCTCAGTGGTTTGG -3'
(R):5'- CCTGTAATAAAGTGTGCTCCCC -3'
Sequencing Primer
(F):5'- CTCATCAGAGCTATGTAGGCG -3'
(R):5'- CACAGGGGATCACAGCTAAAC -3'
|
| Posted On |
2016-06-21 |
Incidental Mutation