Mutagenetix > Incidental Mutation

Incidental Mutation 'R5135:Dnah12'

396163

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

DHC3, Hdhc3, HL-19, Dnahc7l, 4921531P07Rik, LOC380889, DLP12, HL19, Dnahc12

MMRRC Submission

043261-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.184) question?

Stock #

R5135 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

26693274-26891703 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 26770477 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 1191 (D1191E)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433] [ENSMUST00000073309]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000022433
AA Change: D1191E

PolyPhen 2 Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: D1191E

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000073309

SMART Domains

Protein: ENSMUSP00000073035
Gene: ENSMUSG00000021879

Domain	Start	End	E-Value	Type
Pfam:AAA_6	1	203	4e-84	PFAM

Meta Mutation Damage Score

0.0851

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.3%
20x: 95.1%

Validation Efficiency

98% (82/84)

Allele List at MGI

Other mutations in this stock

Total: 80 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700056E22Rik	T	C	1: 184,033,506 (GRCm38)	S119G	probably benign	Het
4930553M12Rik	G	T	4: 88,868,271 (GRCm38)	H37N	unknown	Het
Adam10	T	A	9: 70,766,074 (GRCm38)	C496S	probably damaging	Het
Akap2	G	T	4: 57,855,912 (GRCm38)	A414S	probably benign	Het
Aldh18a1	A	C	19: 40,554,817 (GRCm38)		probably benign	Het
Alox5	A	G	6: 116,413,786 (GRCm38)	F468S	probably benign	Het
Ankrd50	T	C	3: 38,455,803 (GRCm38)	H805R	probably damaging	Het
Ap2s1	T	A	7: 16,747,323 (GRCm38)	D72E	probably damaging	Het
Apaf1	T	C	10: 91,060,094 (GRCm38)	Y372C	probably damaging	Het
Apob	C	T	12: 8,010,086 (GRCm38)	T2823I	probably damaging	Het
Bhmt	A	G	13: 93,627,323 (GRCm38)	V70A	probably damaging	Het
Cdc42bpg	T	A	19: 6,320,618 (GRCm38)	L1247H	probably damaging	Het
Cel	A	G	2: 28,559,423 (GRCm38)	V264A	probably benign	Het
Celsr2	T	C	3: 108,398,659 (GRCm38)	N2043S	probably damaging	Het
Clca4a	A	T	3: 144,954,946 (GRCm38)	W706R	probably damaging	Het
Col22a1	G	T	15: 71,799,337 (GRCm38)	P1058Q	unknown	Het
Cyp4a14	A	G	4: 115,489,960 (GRCm38)		probably null	Het
Dhx30	T	G	9: 110,098,795 (GRCm38)	R55S	probably damaging	Het
Dlgap5	C	T	14: 47,399,665 (GRCm38)	R452H	probably damaging	Het
Dock3	A	T	9: 106,932,997 (GRCm38)	I164N	probably damaging	Het
Edrf1	T	A	7: 133,651,044 (GRCm38)	M436K	probably benign	Het
Eif2ak2	T	A	17: 78,866,345 (GRCm38)	Y268F	probably damaging	Het
Evi2a	G	A	11: 79,527,451 (GRCm38)	T111M	possibly damaging	Het
Fzd4	A	G	7: 89,407,501 (GRCm38)	E252G	probably damaging	Het
Gcm2	A	G	13: 41,102,959 (GRCm38)	V438A	probably benign	Het
Gm10722	T	C	9: 3,000,937 (GRCm38)	C6R	probably benign	Het
Gm21994	A	T	2: 150,255,490 (GRCm38)	Y34*	probably null	Het
Gm4787	G	C	12: 81,377,830 (GRCm38)	T518S	probably benign	Het
Gm4846	T	C	1: 166,483,982 (GRCm38)	D436G	probably damaging	Het
Gm5414	T	A	15: 101,627,768 (GRCm38)	I141F	probably damaging	Het
Gm6185	T	A	1: 161,198,231 (GRCm38)		noncoding transcript	Het
Grip2	T	C	6: 91,773,916 (GRCm38)	E776G	possibly damaging	Het
H2-Ob	T	A	17: 34,243,516 (GRCm38)	V160E	probably benign	Het
Hormad1	T	C	3: 95,585,220 (GRCm38)		probably benign	Het
Ighv2-1	A	T	12: 113,574,462 (GRCm38)		probably benign	Het
Igkv4-92	A	T	6: 68,755,554 (GRCm38)	C14S	probably benign	Het
Iqsec3	T	C	6: 121,383,919 (GRCm38)	I993M	probably damaging	Het
Kdm5b	T	A	1: 134,588,746 (GRCm38)		probably benign	Het
Kitl	T	C	10: 100,088,222 (GRCm38)		probably null	Het
Klhl26	G	T	8: 70,452,718 (GRCm38)	R100S	probably benign	Het
Kpna4	C	T	3: 69,092,809 (GRCm38)		probably null	Het
Lama5	T	A	2: 180,202,220 (GRCm38)	N383Y	possibly damaging	Het
Large1	T	G	8: 72,818,096 (GRCm38)	I685L	probably benign	Het
Larp4b	A	G	13: 9,170,737 (GRCm38)	E590G	probably damaging	Het
Liph	A	T	16: 21,956,165 (GRCm38)	C425*	probably null	Het
Lrrc31	A	T	3: 30,684,890 (GRCm38)	C327*	probably null	Het
Lrrc36	T	C	8: 105,463,898 (GRCm38)	V733A	probably benign	Het
Mmel1	T	A	4: 154,882,324 (GRCm38)	I83K	probably benign	Het
Myo16	G	T	8: 10,476,114 (GRCm38)	V885L	probably benign	Het
Naip2	A	T	13: 100,179,440 (GRCm38)	N277K	probably damaging	Het
Ncapg2	T	A	12: 116,427,786 (GRCm38)	I485N	possibly damaging	Het
Npc1l1	A	T	11: 6,224,245 (GRCm38)	Y687N	possibly damaging	Het
Obscn	A	T	11: 59,129,653 (GRCm38)	V922E	probably damaging	Het
Oc90	A	G	15: 65,883,830 (GRCm38)	S223P	probably benign	Het
Olfr1	AGCGGTCGTAGGC	AGC	11: 73,395,654 (GRCm38)		probably null	Het
Olfr1253	A	T	2: 89,751,895 (GRCm38)	L311H	possibly damaging	Het
Olfr1508	T	C	14: 52,463,854 (GRCm38)	I52V	probably benign	Het
Pdlim5	C	T	3: 142,304,365 (GRCm38)	R174H	probably benign	Het
Pex5l	G	T	3: 32,955,831 (GRCm38)	A386E	probably damaging	Het
Plcxd1	T	A	5: 110,101,363 (GRCm38)		probably benign	Het
Pramef8	T	G	4: 143,419,009 (GRCm38)	S349R	probably benign	Het
Prl8a1	A	T	13: 27,579,819 (GRCm38)		probably null	Het
Ryr2	G	T	13: 11,662,130 (GRCm38)	N3278K	probably benign	Het
Sacm1l	A	G	9: 123,577,025 (GRCm38)	M324V	probably benign	Het
Sdad1	T	C	5: 92,303,934 (GRCm38)	T143A	probably benign	Het
Sec11a	A	T	7: 80,923,064 (GRCm38)		probably benign	Het
Sema6a	A	G	18: 47,291,172 (GRCm38)	V223A	probably damaging	Het
Serpinb6c	A	G	13: 33,880,097 (GRCm38)	V325A	probably damaging	Het
Slc4a2	G	A	5: 24,430,127 (GRCm38)	A177T	possibly damaging	Het
Slc5a4a	A	G	10: 76,147,594 (GRCm38)	N22D	unknown	Het
Stard13	C	T	5: 151,062,767 (GRCm38)	W308*	probably null	Het
Tanc2	C	T	11: 105,857,553 (GRCm38)	L504F	possibly damaging	Het
Tfap2e	G	T	4: 126,720,544 (GRCm38)	N282K	probably damaging	Het
Uhrf1bp1l	T	C	10: 89,789,355 (GRCm38)	I48T	probably damaging	Het
Usp36	G	T	11: 118,264,905 (GRCm38)	T682K	possibly damaging	Het
Zc3h11a	T	C	1: 133,633,789 (GRCm38)	T315A	probably benign	Het
Zfa-ps	T	A	10: 52,543,022 (GRCm38)		noncoding transcript	Het
Zfp663	A	T	2: 165,353,670 (GRCm38)	C210S	possibly damaging	Het
Zfp747	T	C	7: 127,374,394 (GRCm38)	I201M	probably damaging	Het
Zic4	C	T	9: 91,384,152 (GRCm38)	T276M	probably damaging	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,771,005 (GRCm38)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,710,275 (GRCm38)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,722,160 (GRCm38)	missense	probably benign
IGL02082:Dnah12	APN	14	26,707,162 (GRCm38)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,716,577 (GRCm38)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,773,112 (GRCm38)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,706,917 (GRCm38)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,709,161 (GRCm38)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,773,722 (GRCm38)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,724,512 (GRCm38)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,697,398 (GRCm38)	missense	probably benign	0.06
drippings	UTSW	14	26,854,804 (GRCm38)	missense	probably damaging	1.00
grueben	UTSW	14	26,878,079 (GRCm38)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,872,740 (GRCm38)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,772,644 (GRCm38)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,798,899 (GRCm38)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,799,999 (GRCm38)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,706,117 (GRCm38)	splice site	probably null
R0364:Dnah12	UTSW	14	26,724,473 (GRCm38)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,798,899 (GRCm38)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,709,310 (GRCm38)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,884,265 (GRCm38)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,800,013 (GRCm38)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,739,220 (GRCm38)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,710,248 (GRCm38)	missense	probably benign
R1503:Dnah12	UTSW	14	26,773,692 (GRCm38)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,816,322 (GRCm38)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,766,190 (GRCm38)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,778,883 (GRCm38)	missense	possibly damaging	0.71
R1758:Dnah12	UTSW	14	26,766,114 (GRCm38)	missense	probably benign	0.02
R1826:Dnah12	UTSW	14	26,711,019 (GRCm38)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,800,075 (GRCm38)	missense	probably damaging	1.00
R1829:Dnah12	UTSW	14	26,773,023 (GRCm38)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,709,257 (GRCm38)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,697,398 (GRCm38)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,792,264 (GRCm38)	splice site	probably null
R1933:Dnah12	UTSW	14	26,734,495 (GRCm38)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,814,459 (GRCm38)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,781,528 (GRCm38)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,766,141 (GRCm38)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,724,458 (GRCm38)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,724,458 (GRCm38)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,781,787 (GRCm38)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,739,330 (GRCm38)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,769,950 (GRCm38)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,876,950 (GRCm38)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,693,470 (GRCm38)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,770,972 (GRCm38)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,812,790 (GRCm38)	missense	probably benign
R3729:Dnah12	UTSW	14	26,706,065 (GRCm38)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,770,923 (GRCm38)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,710,211 (GRCm38)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,856,616 (GRCm38)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,771,051 (GRCm38)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,723,599 (GRCm38)	missense	probably benign
R4065:Dnah12	UTSW	14	26,770,448 (GRCm38)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,693,567 (GRCm38)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,709,186 (GRCm38)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,798,926 (GRCm38)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,798,926 (GRCm38)	missense	probably benign	0.01
R4348:Dnah12	UTSW	14	26,814,541 (GRCm38)	missense	possibly damaging	0.94
R4457:Dnah12	UTSW	14	26,815,507 (GRCm38)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,734,603 (GRCm38)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,734,603 (GRCm38)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,871,855 (GRCm38)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,876,958 (GRCm38)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,770,022 (GRCm38)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,773,014 (GRCm38)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,772,594 (GRCm38)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,735,758 (GRCm38)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,706,839 (GRCm38)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,872,317 (GRCm38)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,781,784 (GRCm38)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,781,784 (GRCm38)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,716,629 (GRCm38)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,718,046 (GRCm38)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,710,170 (GRCm38)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,734,570 (GRCm38)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,861,805 (GRCm38)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,891,524 (GRCm38)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,716,700 (GRCm38)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,710,171 (GRCm38)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,710,171 (GRCm38)	missense	probably benign	0.03
R5043:Dnah12	UTSW	14	26,884,190 (GRCm38)	missense	probably damaging	1.00
R5049:Dnah12	UTSW	14	26,735,697 (GRCm38)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,718,000 (GRCm38)	missense	probably benign	0.00
R5149:Dnah12	UTSW	14	26,850,926 (GRCm38)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,849,363 (GRCm38)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,769,985 (GRCm38)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,693,486 (GRCm38)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,773,830 (GRCm38)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,879,738 (GRCm38)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,814,537 (GRCm38)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,774,342 (GRCm38)	splice site	probably null
R5389:Dnah12	UTSW	14	26,735,749 (GRCm38)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,859,299 (GRCm38)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,771,050 (GRCm38)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,710,269 (GRCm38)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,815,495 (GRCm38)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,770,518 (GRCm38)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,854,921 (GRCm38)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,706,884 (GRCm38)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,770,008 (GRCm38)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,706,918 (GRCm38)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,706,867 (GRCm38)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,886,871 (GRCm38)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,697,341 (GRCm38)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,717,911 (GRCm38)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,875,270 (GRCm38)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,773,685 (GRCm38)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,861,769 (GRCm38)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,710,257 (GRCm38)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,854,804 (GRCm38)	missense	probably damaging	1.00
R6277:Dnah12	UTSW	14	26,770,482 (GRCm38)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,717,974 (GRCm38)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,706,834 (GRCm38)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,878,051 (GRCm38)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,872,455 (GRCm38)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,735,710 (GRCm38)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,735,692 (GRCm38)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,872,749 (GRCm38)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,796,223 (GRCm38)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,707,228 (GRCm38)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,801,513 (GRCm38)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,735,749 (GRCm38)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,878,079 (GRCm38)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,799,076 (GRCm38)	splice site	probably null
R7001:Dnah12	UTSW	14	26,879,724 (GRCm38)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,876,998 (GRCm38)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,735,680 (GRCm38)	missense	probably benign
R7107:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,801,413 (GRCm38)	missense	probably damaging	0.99
R7150:Dnah12	UTSW	14	26,861,732 (GRCm38)	missense	probably damaging	0.99
R7188:Dnah12	UTSW	14	26,814,413 (GRCm38)	missense	probably benign	0.04
R7201:Dnah12	UTSW	14	26,814,622 (GRCm38)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,781,485 (GRCm38)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,854,880 (GRCm38)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,766,577 (GRCm38)	splice site	probably null
R7339:Dnah12	UTSW	14	26,872,320 (GRCm38)	missense	probably benign
R7363:Dnah12	UTSW	14	26,724,611 (GRCm38)	missense	probably benign
R7426:Dnah12	UTSW	14	26,724,626 (GRCm38)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,856,635 (GRCm38)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,770,503 (GRCm38)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,859,316 (GRCm38)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,859,316 (GRCm38)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,781,380 (GRCm38)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,785,933 (GRCm38)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,796,219 (GRCm38)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,829,329 (GRCm38)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,856,529 (GRCm38)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,856,542 (GRCm38)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,709,272 (GRCm38)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,706,881 (GRCm38)	missense	probably benign
R8263:Dnah12	UTSW	14	26,891,464 (GRCm38)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,812,603 (GRCm38)	missense	probably benign
R8336:Dnah12	UTSW	14	26,711,065 (GRCm38)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,854,831 (GRCm38)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,885,912 (GRCm38)	missense	probably benign
R8458:Dnah12	UTSW	14	26,826,892 (GRCm38)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,853,796 (GRCm38)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,774,270 (GRCm38)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,830,625 (GRCm38)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,707,263 (GRCm38)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,693,602 (GRCm38)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,734,563 (GRCm38)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,722,120 (GRCm38)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,824,546 (GRCm38)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,770,368 (GRCm38)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,814,612 (GRCm38)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,849,298 (GRCm38)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,723,905 (GRCm38)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,849,298 (GRCm38)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,815,417 (GRCm38)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,773,059 (GRCm38)	missense	probably benign
R9322:Dnah12	UTSW	14	26,770,977 (GRCm38)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,856,550 (GRCm38)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,792,211 (GRCm38)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,773,756 (GRCm38)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,850,537 (GRCm38)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,875,324 (GRCm38)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,875,324 (GRCm38)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,693,464 (GRCm38)	missense	probably benign
R9581:Dnah12	UTSW	14	26,770,028 (GRCm38)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,868,914 (GRCm38)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,801,553 (GRCm38)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,814,480 (GRCm38)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,816,288 (GRCm38)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,814,645 (GRCm38)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,875,215 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGTGAGATATATGTTCTAGGCATAGTC -3'
(R):5'- CTGAAAATCTGTATCATGTGAGACACC -3'

Sequencing Primer
(F):5'- ATGTTCTAGGCATAGTCATACGTG -3'
(R):5'- GGGTAGCCTAGTCTACATAGCTAC -3'

Posted On

2016-06-21