Mutagenetix > Incidental Mutation

Incidental Mutation 'R5169:Nav2'

397446

Institutional Source

Beutler Lab

Gene Symbol

Nav2

Ensembl Gene

ENSMUSG00000052512

Gene Name

neuron navigator 2

Synonyms

Rainb1, Unc53H2, 5330421F07Rik, POMFIL2, HELAD1, RAINB2

MMRRC Submission

042749-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.550) question?

Stock #

R5169 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

48608796-49259838 bp(+) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 49198231 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Stop codon at position 1287 (Q1287*)

Ref Sequence

ENSEMBL: ENSMUSP00000139045 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000064395] [ENSMUST00000183659] [ENSMUST00000184109] [ENSMUST00000184945]

AlphaFold

E9Q842

Predicted Effect

probably null
Transcript: ENSMUST00000064395
AA Change: Q1287*

SMART Domains

Protein: ENSMUSP00000067448
Gene: ENSMUSG00000052512
AA Change: Q1287*

Domain	Start	End	E-Value	Type
CH	84	187	1.58e-13	SMART
low complexity region	202	210	N/A	INTRINSIC
low complexity region	297	310	N/A	INTRINSIC
low complexity region	337	348	N/A	INTRINSIC
low complexity region	412	424	N/A	INTRINSIC
coiled coil region	486	516	N/A	INTRINSIC
low complexity region	580	591	N/A	INTRINSIC
low complexity region	613	625	N/A	INTRINSIC
low complexity region	640	662	N/A	INTRINSIC
low complexity region	846	857	N/A	INTRINSIC
low complexity region	920	944	N/A	INTRINSIC
low complexity region	947	967	N/A	INTRINSIC
low complexity region	990	1004	N/A	INTRINSIC
low complexity region	1062	1074	N/A	INTRINSIC
low complexity region	1343	1360	N/A	INTRINSIC
low complexity region	1368	1385	N/A	INTRINSIC
low complexity region	1417	1432	N/A	INTRINSIC
low complexity region	1454	1466	N/A	INTRINSIC
low complexity region	1526	1540	N/A	INTRINSIC
low complexity region	1614	1628	N/A	INTRINSIC
coiled coil region	1630	1717	N/A	INTRINSIC
low complexity region	1789	1800	N/A	INTRINSIC
coiled coil region	1841	1909	N/A	INTRINSIC
AAA	2093	2247	1.69e-5	SMART
low complexity region	2404	2430	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000183659
AA Change: Q1226*

SMART Domains

Protein: ENSMUSP00000139309
Gene: ENSMUSG00000052512
AA Change: Q1226*

Domain	Start	End	E-Value	Type
low complexity region	2	11	N/A	INTRINSIC
CH	23	126	6.19e-16	SMART
low complexity region	141	149	N/A	INTRINSIC
low complexity region	236	249	N/A	INTRINSIC
low complexity region	276	287	N/A	INTRINSIC
low complexity region	351	363	N/A	INTRINSIC
coiled coil region	425	455	N/A	INTRINSIC
low complexity region	519	530	N/A	INTRINSIC
low complexity region	552	564	N/A	INTRINSIC
low complexity region	579	601	N/A	INTRINSIC
low complexity region	785	796	N/A	INTRINSIC
low complexity region	859	883	N/A	INTRINSIC
low complexity region	886	906	N/A	INTRINSIC
low complexity region	929	943	N/A	INTRINSIC
low complexity region	1001	1013	N/A	INTRINSIC
low complexity region	1282	1299	N/A	INTRINSIC
low complexity region	1307	1324	N/A	INTRINSIC
low complexity region	1356	1371	N/A	INTRINSIC
low complexity region	1393	1405	N/A	INTRINSIC
low complexity region	1465	1479	N/A	INTRINSIC
low complexity region	1553	1567	N/A	INTRINSIC
coiled coil region	1569	1656	N/A	INTRINSIC
low complexity region	1728	1739	N/A	INTRINSIC
coiled coil region	1780	1848	N/A	INTRINSIC
AAA	2032	2186	1.69e-5	SMART
low complexity region	2343	2369	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000184109
AA Change: Q98*

SMART Domains

Protein: ENSMUSP00000138846
Gene: ENSMUSG00000052512
AA Change: Q98*

Domain	Start	End	E-Value	Type
low complexity region	154	171	N/A	INTRINSIC
low complexity region	179	196	N/A	INTRINSIC
low complexity region	228	243	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000184945
AA Change: Q1287*

SMART Domains

Protein: ENSMUSP00000139045
Gene: ENSMUSG00000052512
AA Change: Q1287*

Domain	Start	End	E-Value	Type
CH	84	187	1.58e-13	SMART
low complexity region	202	210	N/A	INTRINSIC
low complexity region	297	310	N/A	INTRINSIC
low complexity region	337	348	N/A	INTRINSIC
low complexity region	412	424	N/A	INTRINSIC
coiled coil region	486	516	N/A	INTRINSIC
low complexity region	580	591	N/A	INTRINSIC
low complexity region	613	625	N/A	INTRINSIC
low complexity region	640	662	N/A	INTRINSIC
low complexity region	846	857	N/A	INTRINSIC
low complexity region	920	944	N/A	INTRINSIC
low complexity region	947	967	N/A	INTRINSIC
low complexity region	990	1004	N/A	INTRINSIC
low complexity region	1062	1074	N/A	INTRINSIC
low complexity region	1343	1360	N/A	INTRINSIC
low complexity region	1368	1385	N/A	INTRINSIC
low complexity region	1417	1432	N/A	INTRINSIC
low complexity region	1454	1466	N/A	INTRINSIC
low complexity region	1526	1540	N/A	INTRINSIC
low complexity region	1614	1628	N/A	INTRINSIC
coiled coil region	1630	1717	N/A	INTRINSIC
low complexity region	1789	1800	N/A	INTRINSIC
coiled coil region	1841	1909	N/A	INTRINSIC
AAA	2093	2247	1.69e-5	SMART
low complexity region	2404	2430	N/A	INTRINSIC

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Homozygous null mice display impaired olfaction and hearing, increased latency in a hot plate test, degeneration of the optic nerve, decreased exploration in new environments, and weight loss. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 62 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb5	A	T	12: 118,841,552 (GRCm39)	Y964*	probably null	Het
Acsbg2	T	C	17: 57,156,913 (GRCm39)	K375R	probably benign	Het
Ago4	C	A	4: 126,405,520 (GRCm39)	R415L	probably benign	Het
Alpk1	A	T	3: 127,464,750 (GRCm39)	I1176N	probably damaging	Het
Arhgap25	A	T	6: 87,440,252 (GRCm39)	I465N	possibly damaging	Het
Arhgef10	A	G	8: 14,980,051 (GRCm39)	D97G	possibly damaging	Het
Cdc37	T	A	9: 21,052,413 (GRCm39)	M299L	probably benign	Het
Ddx54	C	A	5: 120,761,328 (GRCm39)	H453Q	probably damaging	Het
Dip2b	T	C	15: 100,102,994 (GRCm39)	Y1102H	probably damaging	Het
Dmpk	C	G	7: 18,821,944 (GRCm39)	L301V	probably benign	Het
Dop1a	T	C	9: 86,415,074 (GRCm39)	F1939L	probably damaging	Het
Igkv4-80	A	C	6: 68,993,649 (GRCm39)	S81A	probably benign	Het
Ints7	T	C	1: 191,345,202 (GRCm39)	F631L	probably benign	Het
Itih1	A	T	14: 30,655,403 (GRCm39)	Y597*	probably null	Het
Kctd1	T	C	18: 15,195,822 (GRCm39)	E267G	possibly damaging	Het
Lrrc8e	A	G	8: 4,284,329 (GRCm39)	T185A	probably benign	Het
Maco1	T	C	4: 134,555,774 (GRCm39)	H233R	probably benign	Het
Masp2	T	C	4: 148,690,571 (GRCm39)	I276T	probably damaging	Het
Med17	A	T	9: 15,188,900 (GRCm39)	F122I	probably benign	Het
Milr1	C	T	11: 106,645,754 (GRCm39)	R99*	probably null	Het
Mpp4	T	C	1: 59,169,256 (GRCm39)		probably null	Het
Ms4a4d	C	T	19: 11,535,340 (GRCm39)	P213S	possibly damaging	Het
Mtcl1	T	C	17: 66,650,818 (GRCm39)	N1100S	probably benign	Het
Myom3	T	C	4: 135,502,889 (GRCm39)	I322T	probably benign	Het
Nr3c2	A	T	8: 77,635,666 (GRCm39)	N256Y	probably damaging	Het
Nrde2	A	G	12: 100,095,552 (GRCm39)		probably null	Het
Otog	G	T	7: 45,947,572 (GRCm39)	A2242S	probably benign	Het
Otx1	C	A	11: 21,947,037 (GRCm39)	A91S	probably damaging	Het
Pcdh18	T	C	3: 49,710,415 (GRCm39)	D300G	possibly damaging	Het
Pcdh8	G	A	14: 80,005,095 (GRCm39)	P880S	probably benign	Het
Pcid2	A	G	8: 13,129,632 (GRCm39)		probably null	Het
Phkb	A	G	8: 86,623,120 (GRCm39)	H148R	probably benign	Het
Pik3r4	T	C	9: 105,555,360 (GRCm39)	S1106P	probably benign	Het
Pnpla7	A	T	2: 24,940,321 (GRCm39)	M1067L	probably benign	Het
Pp2d1	C	A	17: 53,814,930 (GRCm39)	G598V	possibly damaging	Het
Ppm1d	C	T	11: 85,223,196 (GRCm39)	A267V	probably damaging	Het
Psg29	C	T	7: 16,945,578 (GRCm39)	P383S	probably damaging	Het
Rc3h2	A	T	2: 37,295,324 (GRCm39)	F231I	probably damaging	Het
Rpl14	T	A	9: 120,401,254 (GRCm39)	D32E	possibly damaging	Het
Rpl32	G	T	6: 115,783,949 (GRCm39)	N92K	probably benign	Het
Rragc	A	G	4: 123,829,457 (GRCm39)	N391S	probably damaging	Het
Ryr3	C	T	2: 112,501,005 (GRCm39)	E3563K	possibly damaging	Het
Sh3rf2	A	G	18: 42,286,126 (GRCm39)	M508V	probably benign	Het
Shoc1	T	A	4: 59,059,618 (GRCm39)	Y1014F	possibly damaging	Het
Slc24a3	G	A	2: 145,482,184 (GRCm39)	C614Y	probably benign	Het
Spata31d1b	T	C	13: 59,864,309 (GRCm39)	S486P	probably damaging	Het
Spi1	A	T	2: 90,945,428 (GRCm39)	K170*	probably null	Het
Srgn	C	A	10: 62,330,866 (GRCm39)	D80Y	probably damaging	Het
St6galnac6	A	G	2: 32,504,857 (GRCm39)	K87R	possibly damaging	Het
Sytl3	A	T	17: 6,982,945 (GRCm39)	K134*	probably null	Het
Szt2	T	C	4: 118,247,027 (GRCm39)	T863A	probably benign	Het
Tcea3	A	T	4: 135,992,181 (GRCm39)		probably null	Het
Tg	T	A	15: 66,550,629 (GRCm39)	L253*	probably null	Het
Timm8a2	T	A	14: 122,272,138 (GRCm39)	S14T	probably benign	Het
Tppp3	G	C	8: 106,194,501 (GRCm39)	N166K	probably benign	Het
Trav2	G	A	14: 52,804,759 (GRCm39)	V4M	probably benign	Het
Trmt5	T	C	12: 73,329,495 (GRCm39)	D221G	probably damaging	Het
Ttc27	T	A	17: 75,054,690 (GRCm39)	L332*	probably null	Het
V1rd19	A	G	7: 23,703,209 (GRCm39)	N225S	possibly damaging	Het
Wdr20rt	A	T	12: 65,274,184 (GRCm39)	Q448L	probably damaging	Het
Zc3h7b	A	T	15: 81,657,515 (GRCm39)	N185I	probably benign	Het
Zmpste24	A	T	4: 120,925,914 (GRCm39)	I351N	probably damaging	Het

Other mutations in Nav2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01097:Nav2	APN	7	49,220,942 (GRCm39)	missense	probably damaging	1.00
IGL01150:Nav2	APN	7	49,102,269 (GRCm39)	missense	probably benign	0.17
IGL01649:Nav2	APN	7	49,225,477 (GRCm39)	missense	probably damaging	1.00
IGL01662:Nav2	APN	7	49,220,957 (GRCm39)	missense	probably damaging	1.00
IGL02297:Nav2	APN	7	49,243,977 (GRCm39)	missense	probably damaging	0.98
IGL02313:Nav2	APN	7	49,208,521 (GRCm39)	missense	probably damaging	0.99
IGL02441:Nav2	APN	7	49,102,260 (GRCm39)	missense	probably damaging	1.00
IGL02472:Nav2	APN	7	49,195,789 (GRCm39)	missense	probably damaging	1.00
IGL02477:Nav2	APN	7	49,232,623 (GRCm39)	missense	probably damaging	0.99
IGL02725:Nav2	APN	7	49,214,843 (GRCm39)	missense	probably damaging	1.00
IGL02944:Nav2	APN	7	49,070,004 (GRCm39)	missense	probably damaging	0.99
IGL02953:Nav2	APN	7	49,198,171 (GRCm39)	missense	probably damaging	1.00
IGL03105:Nav2	APN	7	49,114,627 (GRCm39)	missense	probably damaging	1.00
IGL03234:Nav2	APN	7	49,111,756 (GRCm39)	missense	possibly damaging	0.94
IGL03274:Nav2	APN	7	49,011,847 (GRCm39)	missense	probably damaging	1.00
IGL03294:Nav2	APN	7	49,141,205 (GRCm39)	nonsense	probably null
R0006:Nav2	UTSW	7	49,102,978 (GRCm39)	missense	possibly damaging	0.50
R0070:Nav2	UTSW	7	49,220,462 (GRCm39)	missense	probably damaging	1.00
R0113:Nav2	UTSW	7	49,185,701 (GRCm39)	missense	probably damaging	1.00
R0306:Nav2	UTSW	7	49,195,651 (GRCm39)	missense	probably benign	0.01
R0346:Nav2	UTSW	7	49,254,333 (GRCm39)	missense	probably benign	0.11
R0539:Nav2	UTSW	7	49,111,686 (GRCm39)	missense	probably damaging	1.00
R0669:Nav2	UTSW	7	49,058,431 (GRCm39)	missense	probably damaging	1.00
R0785:Nav2	UTSW	7	49,070,081 (GRCm39)	missense	probably benign	0.06
R0970:Nav2	UTSW	7	49,233,901 (GRCm39)	missense	probably damaging	1.00
R1162:Nav2	UTSW	7	49,185,788 (GRCm39)	splice site	probably benign
R1274:Nav2	UTSW	7	49,254,178 (GRCm39)	nonsense	probably null
R1463:Nav2	UTSW	7	49,185,710 (GRCm39)	missense	probably damaging	1.00
R1464:Nav2	UTSW	7	49,011,952 (GRCm39)	missense	probably damaging	1.00
R1464:Nav2	UTSW	7	49,011,952 (GRCm39)	missense	probably damaging	1.00
R1536:Nav2	UTSW	7	49,195,682 (GRCm39)	missense	probably damaging	1.00
R1612:Nav2	UTSW	7	49,220,959 (GRCm39)	missense	probably damaging	1.00
R1638:Nav2	UTSW	7	49,102,213 (GRCm39)	missense	probably benign
R1731:Nav2	UTSW	7	49,197,922 (GRCm39)	missense	probably damaging	1.00
R1734:Nav2	UTSW	7	49,225,468 (GRCm39)	missense	probably damaging	1.00
R1865:Nav2	UTSW	7	49,197,943 (GRCm39)	missense	possibly damaging	0.95
R1945:Nav2	UTSW	7	49,114,620 (GRCm39)	missense	probably damaging	1.00
R1997:Nav2	UTSW	7	49,198,219 (GRCm39)	missense	probably benign	0.16
R2061:Nav2	UTSW	7	49,248,645 (GRCm39)	splice site	probably benign
R2117:Nav2	UTSW	7	49,114,328 (GRCm39)	missense	probably benign	0.00
R2174:Nav2	UTSW	7	49,102,411 (GRCm39)	missense	probably damaging	0.99
R2182:Nav2	UTSW	7	49,247,002 (GRCm39)	missense	probably benign	0.38
R2251:Nav2	UTSW	7	49,103,025 (GRCm39)	missense	probably damaging	1.00
R2283:Nav2	UTSW	7	49,141,152 (GRCm39)	missense	probably damaging	1.00
R2343:Nav2	UTSW	7	49,248,565 (GRCm39)	missense	possibly damaging	0.82
R2472:Nav2	UTSW	7	49,058,632 (GRCm39)	missense	probably benign
R2568:Nav2	UTSW	7	49,247,312 (GRCm39)	missense	probably damaging	1.00
R2656:Nav2	UTSW	7	49,195,690 (GRCm39)	missense	probably damaging	1.00
R2964:Nav2	UTSW	7	49,206,780 (GRCm39)	missense	probably damaging	1.00
R2966:Nav2	UTSW	7	49,206,780 (GRCm39)	missense	probably damaging	1.00
R3817:Nav2	UTSW	7	49,114,310 (GRCm39)	missense	probably benign	0.00
R3834:Nav2	UTSW	7	49,195,606 (GRCm39)	missense	possibly damaging	0.91
R4207:Nav2	UTSW	7	49,246,979 (GRCm39)	missense	probably damaging	1.00
R4207:Nav2	UTSW	7	49,222,046 (GRCm39)	splice site	probably null
R4411:Nav2	UTSW	7	49,047,857 (GRCm39)	missense	probably benign	0.37
R4413:Nav2	UTSW	7	49,047,857 (GRCm39)	missense	probably benign	0.37
R4440:Nav2	UTSW	7	49,225,011 (GRCm39)	splice site	probably benign
R4440:Nav2	UTSW	7	49,201,785 (GRCm39)	missense	possibly damaging	0.86
R4454:Nav2	UTSW	7	49,198,292 (GRCm39)	splice site	probably null
R4729:Nav2	UTSW	7	49,102,567 (GRCm39)	missense	probably benign	0.17
R4801:Nav2	UTSW	7	49,195,600 (GRCm39)	missense	possibly damaging	0.94
R4802:Nav2	UTSW	7	49,195,600 (GRCm39)	missense	possibly damaging	0.94
R4824:Nav2	UTSW	7	49,058,749 (GRCm39)	intron	probably benign
R4887:Nav2	UTSW	7	49,198,182 (GRCm39)	nonsense	probably null
R4908:Nav2	UTSW	7	49,254,258 (GRCm39)	missense	probably damaging	1.00
R4952:Nav2	UTSW	7	48,954,288 (GRCm39)	intron	probably benign
R4965:Nav2	UTSW	7	49,202,625 (GRCm39)	nonsense	probably null
R5224:Nav2	UTSW	7	49,201,473 (GRCm39)	missense	probably benign	0.00
R5249:Nav2	UTSW	7	49,185,661 (GRCm39)	missense	probably damaging	1.00
R5285:Nav2	UTSW	7	49,197,982 (GRCm39)	missense	probably damaging	1.00
R5314:Nav2	UTSW	7	49,058,440 (GRCm39)	small deletion	probably benign
R5320:Nav2	UTSW	7	49,141,121 (GRCm39)	missense	probably benign	0.00
R5377:Nav2	UTSW	7	49,238,908 (GRCm39)	missense	probably benign	0.02
R5471:Nav2	UTSW	7	49,197,917 (GRCm39)	missense	probably damaging	1.00
R5754:Nav2	UTSW	7	49,206,794 (GRCm39)	missense	probably damaging	1.00
R5832:Nav2	UTSW	7	49,197,817 (GRCm39)	splice site	probably null
R5884:Nav2	UTSW	7	49,246,917 (GRCm39)	nonsense	probably null
R5921:Nav2	UTSW	7	48,954,324 (GRCm39)	intron	probably benign
R6180:Nav2	UTSW	7	49,107,915 (GRCm39)	missense	probably benign	0.39
R6208:Nav2	UTSW	7	49,213,851 (GRCm39)	missense	probably damaging	0.99
R6373:Nav2	UTSW	7	49,102,923 (GRCm39)	missense	probably damaging	1.00
R6450:Nav2	UTSW	7	49,244,114 (GRCm39)	missense	probably damaging	1.00
R6522:Nav2	UTSW	7	49,247,281 (GRCm39)	missense	probably damaging	1.00
R6626:Nav2	UTSW	7	49,244,100 (GRCm39)	missense	probably damaging	1.00
R6695:Nav2	UTSW	7	49,114,652 (GRCm39)	missense	probably benign	0.04
R6705:Nav2	UTSW	7	49,201,664 (GRCm39)	missense	probably damaging	1.00
R6842:Nav2	UTSW	7	49,107,917 (GRCm39)	missense	possibly damaging	0.91
R6847:Nav2	UTSW	7	49,141,204 (GRCm39)	missense	probably benign	0.14
R7287:Nav2	UTSW	7	49,070,076 (GRCm39)	missense	probably benign	0.01
R7312:Nav2	UTSW	7	49,111,672 (GRCm39)	missense	possibly damaging	0.55
R7315:Nav2	UTSW	7	49,198,037 (GRCm39)	missense	possibly damaging	0.61
R7337:Nav2	UTSW	7	49,201,521 (GRCm39)	missense	possibly damaging	0.56
R7366:Nav2	UTSW	7	49,203,951 (GRCm39)	splice site	probably null
R7451:Nav2	UTSW	7	49,202,577 (GRCm39)	splice site	probably null
R7545:Nav2	UTSW	7	49,232,605 (GRCm39)	missense	probably damaging	1.00
R7706:Nav2	UTSW	7	49,244,067 (GRCm39)	missense	probably benign	0.35
R7730:Nav2	UTSW	7	49,222,145 (GRCm39)	missense	probably damaging	1.00
R7812:Nav2	UTSW	7	49,246,921 (GRCm39)	missense	probably benign	0.13
R8097:Nav2	UTSW	7	49,237,525 (GRCm39)	missense	probably damaging	1.00
R8110:Nav2	UTSW	7	49,201,698 (GRCm39)	nonsense	probably null
R8119:Nav2	UTSW	7	49,103,232 (GRCm39)	missense	probably damaging	0.99
R8298:Nav2	UTSW	7	49,204,009 (GRCm39)	critical splice donor site	probably null
R8306:Nav2	UTSW	7	49,195,765 (GRCm39)	missense	probably benign	0.33
R8331:Nav2	UTSW	7	49,102,371 (GRCm39)	missense	probably benign
R8402:Nav2	UTSW	7	49,103,185 (GRCm39)	missense	probably benign	0.43
R8421:Nav2	UTSW	7	49,102,269 (GRCm39)	missense	probably benign
R8478:Nav2	UTSW	7	49,111,733 (GRCm39)	missense	probably damaging	0.99
R8724:Nav2	UTSW	7	49,141,184 (GRCm39)	missense	possibly damaging	0.82
R8753:Nav2	UTSW	7	49,102,320 (GRCm39)	missense	probably benign
R8835:Nav2	UTSW	7	49,248,551 (GRCm39)	missense	possibly damaging	0.83
R8933:Nav2	UTSW	7	49,111,705 (GRCm39)	missense	probably damaging	1.00
R8957:Nav2	UTSW	7	49,220,964 (GRCm39)	missense	probably damaging	1.00
R9069:Nav2	UTSW	7	49,208,561 (GRCm39)	missense	probably damaging	0.99
R9095:Nav2	UTSW	7	49,254,293 (GRCm39)	missense	probably damaging	1.00
R9223:Nav2	UTSW	7	49,202,599 (GRCm39)	missense	probably damaging	1.00
R9261:Nav2	UTSW	7	49,246,904 (GRCm39)	missense	probably damaging	1.00
X0023:Nav2	UTSW	7	49,197,647 (GRCm39)	missense	possibly damaging	0.47
Z1177:Nav2	UTSW	7	49,243,971 (GRCm39)	missense	probably benign	0.01
Z1177:Nav2	UTSW	7	49,102,509 (GRCm39)	missense	possibly damaging	0.47

Predicted Primers

PCR Primer
(F):5'- AACATGAGCAGCAAGTCGGC -3'
(R):5'- TTTCCCATCCTGGCATGGAAG -3'

Sequencing Primer
(F):5'- AGCAAGTCGGCAGGCCTG -3'
(R):5'- AAAAAGCAGAGTACAGACCCGTC -3'

Posted On

2016-07-06