Incidental Mutation 'R5170:Zfp941'
ID397504
Institutional Source Beutler Lab
Gene Symbol Zfp941
Ensembl Gene ENSMUSG00000060314
Gene Namezinc finger protein 941
SynonymsBC066028
MMRRC Submission 042750-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.082) question?
Stock #R5170 (G1)
Quality Score225
Status Not validated
Chromosome7
Chromosomal Location140807449-140822178 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) G to A at 140812957 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000147965 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000080651] [ENSMUST00000106052] [ENSMUST00000150053]
Predicted Effect unknown
Transcript: ENSMUST00000080651
AA Change: P163L
SMART Domains Protein: ENSMUSP00000079482
Gene: ENSMUSG00000060314
AA Change: P163L

DomainStartEndE-ValueType
KRAB 4 65 3.88e-21 SMART
ZnF_C2H2 339 361 1.26e-2 SMART
ZnF_C2H2 367 389 1.12e-3 SMART
ZnF_C2H2 395 417 7.78e-3 SMART
ZnF_C2H2 423 445 1.12e-3 SMART
ZnF_C2H2 451 471 1.16e1 SMART
ZnF_C2H2 500 522 2.57e-3 SMART
ZnF_C2H2 528 550 7.9e-4 SMART
ZnF_C2H2 556 578 6.42e-4 SMART
ZnF_C2H2 584 606 1.38e-3 SMART
ZnF_C2H2 612 634 3.69e-4 SMART
Predicted Effect unknown
Transcript: ENSMUST00000106052
AA Change: P163L
SMART Domains Protein: ENSMUSP00000101667
Gene: ENSMUSG00000060314
AA Change: P163L

DomainStartEndE-ValueType
KRAB 4 65 3.88e-21 SMART
ZnF_C2H2 339 361 1.26e-2 SMART
ZnF_C2H2 367 389 1.12e-3 SMART
ZnF_C2H2 395 417 7.78e-3 SMART
ZnF_C2H2 423 445 1.12e-3 SMART
ZnF_C2H2 451 471 1.16e1 SMART
ZnF_C2H2 500 522 2.57e-3 SMART
ZnF_C2H2 528 550 7.9e-4 SMART
ZnF_C2H2 556 578 6.42e-4 SMART
ZnF_C2H2 584 606 1.38e-3 SMART
ZnF_C2H2 612 634 3.69e-4 SMART
ZnF_C2H2 640 662 2.99e-4 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000150053
Coding Region Coverage
  • 1x: 99.2%
  • 3x: 98.6%
  • 10x: 97.3%
  • 20x: 95.4%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acox3 A G 5: 35,588,625 I51V probably benign Het
Agbl2 A G 2: 90,803,197 K559R probably benign Het
Arhgap30 A G 1: 171,408,050 D664G probably benign Het
BC034090 A G 1: 155,213,650 V798A probably damaging Het
Bdp1 A T 13: 100,030,794 C2237* probably null Het
C3 C T 17: 57,223,938 V388M probably damaging Het
Ccdc170 G A 10: 4,514,200 E60K probably damaging Het
Cdh8 G A 8: 99,279,550 T135M probably damaging Het
Cep131 G T 11: 120,070,609 A572E probably damaging Het
Clec16a A G 16: 10,741,791 Y976C probably benign Het
Dmpk C G 7: 19,088,019 L301V probably benign Het
Eno3 A G 11: 70,662,214 I393V probably benign Het
Fbxo47 A G 11: 97,857,694 V305A probably benign Het
Fry G A 5: 150,429,854 V1779M probably benign Het
Gm15293 A T 8: 21,201,680 D26V probably damaging Het
Gtse1 T C 15: 85,864,264 probably null Het
Gucy2e A T 11: 69,235,570 L328Q probably damaging Het
Ifi207 T C 1: 173,730,498 T225A unknown Het
Igkv4-80 A C 6: 69,016,665 S81A probably benign Het
Lamc3 A T 2: 31,887,344 M1L probably benign Het
Lman1l G A 9: 57,615,619 R153* probably null Het
Myo16 A G 8: 10,569,745 D1432G probably benign Het
Nwd2 A T 5: 63,806,037 N988I probably damaging Het
Otx1 C A 11: 21,997,037 A91S probably damaging Het
Parp14 T C 16: 35,857,279 E773G probably benign Het
Psen1 T A 12: 83,714,862 M146K probably damaging Het
Ptx4 G A 17: 25,123,178 R209Q probably benign Het
Slc13a2 T C 11: 78,400,808 T340A probably damaging Het
St8sia1 T C 6: 142,963,708 K21E probably damaging Het
Stxbp1 T C 2: 32,794,674 D581G probably benign Het
Sumo2 G A 11: 115,534,660 probably benign Het
Supt5 G A 7: 28,316,083 P910S probably benign Het
Tbc1d30 T C 10: 121,306,838 Q158R possibly damaging Het
Tenm2 T A 11: 36,024,806 H1968L probably damaging Het
Trmt1 T C 8: 84,695,232 Y220H probably damaging Het
Trp73 C T 4: 154,104,838 E60K possibly damaging Het
Ttn A G 2: 76,787,069 Y8026H probably damaging Het
Zar1l A G 5: 150,517,585 probably null Het
Zfp740 T C 15: 102,209,205 Y117H probably damaging Het
Zp1 C A 19: 10,920,554 V8F possibly damaging Het
Other mutations in Zfp941
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01393:Zfp941 APN 7 140811928 missense probably damaging 1.00
IGL02399:Zfp941 APN 7 140812699 missense probably benign 0.37
IGL03202:Zfp941 APN 7 140813053 missense probably benign 0.02
R0025:Zfp941 UTSW 7 140813272 missense probably benign 0.01
R0025:Zfp941 UTSW 7 140813272 missense probably benign 0.01
R0226:Zfp941 UTSW 7 140813275 missense probably damaging 1.00
R0945:Zfp941 UTSW 7 140811664 missense probably damaging 0.99
R1455:Zfp941 UTSW 7 140812774 missense probably benign 0.29
R1581:Zfp941 UTSW 7 140812120 missense probably benign 0.03
R2474:Zfp941 UTSW 7 140811471 missense probably damaging 1.00
R4052:Zfp941 UTSW 7 140812427 missense possibly damaging 0.81
R4576:Zfp941 UTSW 7 140811590 nonsense probably null
R4604:Zfp941 UTSW 7 140812211 missense probably damaging 1.00
R5311:Zfp941 UTSW 7 140811959 nonsense probably null
R5505:Zfp941 UTSW 7 140811917 missense probably benign 0.03
R5549:Zfp941 UTSW 7 140808108 missense possibly damaging 0.46
R5566:Zfp941 UTSW 7 140812766 missense probably benign 0.01
R5723:Zfp941 UTSW 7 140812850 unclassified probably benign
R5736:Zfp941 UTSW 7 140813060 missense probably benign 0.01
R5861:Zfp941 UTSW 7 140812139 missense probably damaging 1.00
R6041:Zfp941 UTSW 7 140812245 nonsense probably null
R6058:Zfp941 UTSW 7 140812097 missense probably damaging 1.00
R6226:Zfp941 UTSW 7 140812485 missense probably benign 0.01
R6488:Zfp941 UTSW 7 140812750 missense probably benign 0.37
R6824:Zfp941 UTSW 7 140812699 missense probably benign 0.37
R7356:Zfp941 UTSW 7 140812115 missense possibly damaging 0.66
R7554:Zfp941 UTSW 7 140812057 missense possibly damaging 0.69
Z1177:Zfp941 UTSW 7 140812186 missense possibly damaging 0.53
Predicted Primers
Posted On2016-07-06