Incidental Mutation 'R0453:Zfp318'
| ID |
39818 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp318
|
| Ensembl Gene |
ENSMUSG00000015597 |
| Gene Name |
zinc finger protein 318 |
| Synonyms |
2610034E08Rik, TZF, D530032D06Rik |
| MMRRC Submission |
038653-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0453 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
46694657-46731846 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46707634 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 231
(S231P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116544
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113481]
[ENSMUST00000138127]
[ENSMUST00000152472]
|
| AlphaFold |
Q99PP2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113481
AA Change: S231P
PolyPhen 2
Score 0.125 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000109109
Gene: ENSMUSG00000015597
AA Change: S231P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
208 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
376 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
916 |
995 |
2e-4 |
SMART |
|
low complexity region
|
1018 |
1055 |
N/A |
INTRINSIC |
|
ZnF_U1
|
1085 |
1119 |
5.99e-7 |
SMART |
|
ZnF_C2H2
|
1088 |
1112 |
4.5e1 |
SMART |
|
ZnF_U1
|
1155 |
1189 |
2.1e-11 |
SMART |
|
ZnF_C2H2
|
1158 |
1180 |
4.62e1 |
SMART |
|
low complexity region
|
1225 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1358 |
1371 |
N/A |
INTRINSIC |
|
low complexity region
|
1640 |
1651 |
N/A |
INTRINSIC |
|
Blast:HNHc
|
1660 |
1710 |
3e-17 |
BLAST |
|
low complexity region
|
2001 |
2013 |
N/A |
INTRINSIC |
|
low complexity region
|
2110 |
2121 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000138127
AA Change: S231P
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000116544
Gene: ENSMUSG00000015597
AA Change: S231P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
208 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
376 |
N/A |
INTRINSIC |
|
Blast:HOLI
|
854 |
1114 |
8e-19 |
BLAST |
|
SCOP:d1eq1a_
|
916 |
995 |
6e-5 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152472
|
| SMART Domains |
Protein: ENSMUSP00000116132
Gene: ENSMUSG00000015597
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
3 |
30 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0762 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 93.6%
|
| Validation Efficiency |
99% (97/98) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit reduced male fertility and altered IgM and IgD levels. Null mutants displayed normal level of circulating B cells with decreased IgD and increased IgM levels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad10 |
T |
A |
5: 121,765,445 (GRCm39) |
K843* |
probably null |
Het |
| Adam26b |
T |
C |
8: 43,973,387 (GRCm39) |
I538M |
probably benign |
Het |
| Adamtsl1 |
T |
C |
4: 86,150,852 (GRCm39) |
Y337H |
probably damaging |
Het |
| Ak7 |
T |
C |
12: 105,682,307 (GRCm39) |
M156T |
probably damaging |
Het |
| Aldh3a1 |
A |
G |
11: 61,106,338 (GRCm39) |
M238V |
probably benign |
Het |
| Asic4 |
T |
A |
1: 75,450,155 (GRCm39) |
|
probably benign |
Het |
| AW551984 |
A |
G |
9: 39,511,937 (GRCm39) |
S25P |
probably damaging |
Het |
| Bbs7 |
T |
A |
3: 36,661,818 (GRCm39) |
Y127F |
possibly damaging |
Het |
| Bco1 |
G |
A |
8: 117,835,516 (GRCm39) |
E156K |
possibly damaging |
Het |
| Becn1 |
T |
C |
11: 101,181,275 (GRCm39) |
D342G |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,956,749 (GRCm39) |
I3575N |
probably damaging |
Het |
| Brd10 |
T |
C |
19: 29,731,068 (GRCm39) |
Y715C |
probably damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,860,636 (GRCm39) |
M522L |
probably benign |
Het |
| Cerkl |
A |
G |
2: 79,172,795 (GRCm39) |
F293L |
probably benign |
Het |
| Chil3 |
T |
G |
3: 106,056,221 (GRCm39) |
N311T |
probably benign |
Het |
| Cpeb2 |
T |
A |
5: 43,443,056 (GRCm39) |
|
probably benign |
Het |
| Cpxm2 |
A |
G |
7: 131,730,134 (GRCm39) |
S162P |
probably damaging |
Het |
| Cracr2b |
A |
C |
7: 141,044,176 (GRCm39) |
E136A |
probably damaging |
Het |
| Cyp2a4 |
T |
A |
7: 26,012,258 (GRCm39) |
M347K |
probably benign |
Het |
| Dicer1 |
C |
A |
12: 104,668,889 (GRCm39) |
R1264S |
probably benign |
Het |
| Dlgap1 |
T |
A |
17: 71,068,341 (GRCm39) |
N609K |
probably benign |
Het |
| Dnhd1 |
A |
G |
7: 105,323,651 (GRCm39) |
T641A |
probably benign |
Het |
| Egfl8 |
T |
C |
17: 34,833,856 (GRCm39) |
Y74C |
probably damaging |
Het |
| Esyt1 |
A |
G |
10: 128,348,078 (GRCm39) |
S901P |
probably benign |
Het |
| Fam83e |
A |
T |
7: 45,373,372 (GRCm39) |
D246V |
probably damaging |
Het |
| Galnt2 |
T |
C |
8: 125,065,323 (GRCm39) |
|
probably benign |
Het |
| Hdc |
A |
G |
2: 126,436,871 (GRCm39) |
|
probably benign |
Het |
| Herc1 |
A |
C |
9: 66,307,054 (GRCm39) |
Q958P |
probably benign |
Het |
| Iqcg |
T |
A |
16: 32,870,213 (GRCm39) |
|
probably benign |
Het |
| Iqub |
A |
T |
6: 24,450,829 (GRCm39) |
F590Y |
probably damaging |
Het |
| Jak2 |
T |
C |
19: 29,289,238 (GRCm39) |
I1130T |
probably benign |
Het |
| Kbtbd11 |
G |
A |
8: 15,077,499 (GRCm39) |
A33T |
probably benign |
Het |
| Kcnip4 |
A |
G |
5: 48,667,054 (GRCm39) |
L37P |
probably damaging |
Het |
| Klk6 |
A |
G |
7: 43,477,963 (GRCm39) |
N112D |
probably damaging |
Het |
| Kmt2c |
G |
A |
5: 25,559,745 (GRCm39) |
T1011I |
probably damaging |
Het |
| Knl1 |
A |
T |
2: 118,898,869 (GRCm39) |
K190M |
probably damaging |
Het |
| Lama3 |
T |
A |
18: 12,598,535 (GRCm39) |
S981T |
possibly damaging |
Het |
| Lrrc18 |
T |
C |
14: 32,730,608 (GRCm39) |
L49P |
probably damaging |
Het |
| Lrrc31 |
T |
C |
3: 30,741,674 (GRCm39) |
E245G |
probably damaging |
Het |
| Lypd10 |
T |
A |
7: 24,413,712 (GRCm39) |
S243T |
probably benign |
Het |
| Macf1 |
T |
C |
4: 123,338,737 (GRCm39) |
I2456M |
probably benign |
Het |
| Mcm6 |
T |
A |
1: 128,261,292 (GRCm39) |
T771S |
probably benign |
Het |
| Met |
A |
C |
6: 17,534,197 (GRCm39) |
Y680S |
possibly damaging |
Het |
| Mixl1 |
T |
A |
1: 180,524,211 (GRCm39) |
T123S |
probably damaging |
Het |
| Myh8 |
A |
T |
11: 67,183,731 (GRCm39) |
I787F |
probably benign |
Het |
| Myocd |
A |
G |
11: 65,087,051 (GRCm39) |
F292S |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,203,902 (GRCm39) |
|
probably null |
Het |
| Nfe2l1 |
A |
G |
11: 96,718,194 (GRCm39) |
S114P |
probably damaging |
Het |
| Nrxn2 |
T |
C |
19: 6,541,551 (GRCm39) |
S986P |
probably damaging |
Het |
| Oprl1 |
T |
C |
2: 181,360,527 (GRCm39) |
|
probably null |
Het |
| Or11h6 |
T |
C |
14: 50,880,461 (GRCm39) |
V241A |
possibly damaging |
Het |
| Or4a73 |
A |
T |
2: 89,421,095 (GRCm39) |
Y121* |
probably null |
Het |
| Or5b101 |
T |
G |
19: 13,005,295 (GRCm39) |
T133P |
probably damaging |
Het |
| Or6c8 |
A |
G |
10: 128,915,640 (GRCm39) |
F64S |
probably damaging |
Het |
| Or8b53 |
G |
A |
9: 38,667,425 (GRCm39) |
G147D |
probably damaging |
Het |
| Or8c9 |
A |
T |
9: 38,241,467 (GRCm39) |
T195S |
probably benign |
Het |
| Panx2 |
T |
A |
15: 88,952,610 (GRCm39) |
I359N |
probably damaging |
Het |
| Pik3c2b |
T |
A |
1: 133,005,134 (GRCm39) |
V545E |
probably damaging |
Het |
| Piwil4 |
T |
C |
9: 14,638,748 (GRCm39) |
N259S |
probably benign |
Het |
| Plcxd2 |
A |
T |
16: 45,800,919 (GRCm39) |
F102I |
probably damaging |
Het |
| Pld5 |
A |
T |
1: 175,917,522 (GRCm39) |
M75K |
possibly damaging |
Het |
| Pmp22 |
T |
A |
11: 63,041,929 (GRCm39) |
|
probably benign |
Het |
| Polr2a |
A |
G |
11: 69,631,845 (GRCm39) |
S1074P |
possibly damaging |
Het |
| Pop1 |
T |
A |
15: 34,526,352 (GRCm39) |
V649E |
possibly damaging |
Het |
| Prc1 |
A |
G |
7: 79,962,850 (GRCm39) |
N548S |
probably damaging |
Het |
| Prss51 |
T |
C |
14: 64,334,588 (GRCm39) |
L202P |
probably damaging |
Het |
| Rhpn1 |
T |
C |
15: 75,585,428 (GRCm39) |
S576P |
possibly damaging |
Het |
| Rictor |
A |
G |
15: 6,738,123 (GRCm39) |
D20G |
probably benign |
Het |
| Rpl13a-ps1 |
A |
T |
19: 50,018,645 (GRCm39) |
L177* |
probably null |
Het |
| Rpl23a-ps1 |
T |
G |
1: 46,021,087 (GRCm39) |
|
noncoding transcript |
Het |
| Saa2 |
A |
G |
7: 46,402,902 (GRCm39) |
D51G |
probably damaging |
Het |
| Sec31a |
A |
T |
5: 100,551,977 (GRCm39) |
|
probably benign |
Het |
| Secisbp2 |
G |
A |
13: 51,837,361 (GRCm39) |
E841K |
possibly damaging |
Het |
| Serinc1 |
A |
G |
10: 57,393,306 (GRCm39) |
Y437H |
probably damaging |
Het |
| Slc39a12 |
A |
T |
2: 14,440,492 (GRCm39) |
H481L |
probably benign |
Het |
| Suz12 |
T |
A |
11: 79,920,859 (GRCm39) |
N586K |
probably damaging |
Het |
| Synm |
T |
C |
7: 67,386,630 (GRCm39) |
Y344C |
possibly damaging |
Het |
| Tas2r104 |
A |
G |
6: 131,662,304 (GRCm39) |
V135A |
probably benign |
Het |
| Tdrd9 |
T |
C |
12: 112,034,673 (GRCm39) |
S1371P |
probably benign |
Het |
| Tg |
T |
A |
15: 66,700,382 (GRCm39) |
D893E |
probably benign |
Het |
| Thoc5 |
C |
A |
11: 4,868,217 (GRCm39) |
D423E |
possibly damaging |
Het |
| Trim11 |
G |
A |
11: 58,881,361 (GRCm39) |
R418H |
probably damaging |
Het |
| Trim52 |
T |
G |
14: 106,344,399 (GRCm39) |
V19G |
probably damaging |
Het |
| Tuba4a |
C |
A |
1: 75,192,502 (GRCm39) |
V371L |
probably damaging |
Het |
| Ugt8a |
A |
G |
3: 125,708,606 (GRCm39) |
V168A |
probably benign |
Het |
| Ulk1 |
C |
T |
5: 110,938,951 (GRCm39) |
G496R |
probably damaging |
Het |
| Usp40 |
A |
G |
1: 87,874,320 (GRCm39) |
*1236Q |
probably null |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r24 |
A |
G |
6: 123,757,350 (GRCm39) |
|
probably null |
Het |
| Vmn2r53 |
A |
G |
7: 12,316,338 (GRCm39) |
Y494H |
probably damaging |
Het |
| Vmn2r65 |
T |
A |
7: 84,595,442 (GRCm39) |
D414V |
probably benign |
Het |
| Wdr26 |
A |
T |
1: 181,010,444 (GRCm39) |
L519* |
probably null |
Het |
| Wnk1 |
A |
G |
6: 119,940,112 (GRCm39) |
V173A |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zfp398 |
T |
C |
6: 47,842,782 (GRCm39) |
V146A |
probably benign |
Het |
| Zfp410 |
T |
C |
12: 84,378,486 (GRCm39) |
M270T |
probably damaging |
Het |
| Zfp445 |
A |
T |
9: 122,682,578 (GRCm39) |
H454Q |
possibly damaging |
Het |
|
| Other mutations in Zfp318 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00705:Zfp318
|
APN |
17 |
46,723,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00978:Zfp318
|
APN |
17 |
46,724,652 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01016:Zfp318
|
APN |
17 |
46,711,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01310:Zfp318
|
APN |
17 |
46,724,153 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01453:Zfp318
|
APN |
17 |
46,719,942 (GRCm39) |
splice site |
probably null |
|
|
IGL01887:Zfp318
|
APN |
17 |
46,710,094 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02025:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02026:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02070:Zfp318
|
APN |
17 |
46,707,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02182:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02187:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02188:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02189:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02190:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02191:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02192:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02203:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02224:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02230:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02231:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02232:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02233:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02234:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Zfp318
|
APN |
17 |
46,720,043 (GRCm39) |
nonsense |
probably null |
|
|
IGL02792:Zfp318
|
APN |
17 |
46,720,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02826:Zfp318
|
APN |
17 |
46,709,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Wonton
|
UTSW |
17 |
46,720,618 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
I0000:Zfp318
|
UTSW |
17 |
46,710,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0206:Zfp318
|
UTSW |
17 |
46,709,945 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0240:Zfp318
|
UTSW |
17 |
46,707,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0240:Zfp318
|
UTSW |
17 |
46,707,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0281:Zfp318
|
UTSW |
17 |
46,723,540 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0350:Zfp318
|
UTSW |
17 |
46,724,124 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0383:Zfp318
|
UTSW |
17 |
46,724,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1014:Zfp318
|
UTSW |
17 |
46,723,462 (GRCm39) |
nonsense |
probably null |
|
|
R1166:Zfp318
|
UTSW |
17 |
46,720,618 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1208:Zfp318
|
UTSW |
17 |
46,723,446 (GRCm39) |
unclassified |
probably benign |
|
|
R1208:Zfp318
|
UTSW |
17 |
46,723,446 (GRCm39) |
unclassified |
probably benign |
|
|
R1327:Zfp318
|
UTSW |
17 |
46,724,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1330:Zfp318
|
UTSW |
17 |
46,724,684 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1737:Zfp318
|
UTSW |
17 |
46,710,403 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1800:Zfp318
|
UTSW |
17 |
46,722,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1846:Zfp318
|
UTSW |
17 |
46,724,592 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1848:Zfp318
|
UTSW |
17 |
46,716,981 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1861:Zfp318
|
UTSW |
17 |
46,722,366 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1913:Zfp318
|
UTSW |
17 |
46,723,450 (GRCm39) |
unclassified |
probably benign |
|
|
R1913:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R2059:Zfp318
|
UTSW |
17 |
46,707,950 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2085:Zfp318
|
UTSW |
17 |
46,720,590 (GRCm39) |
splice site |
probably null |
|
|
R2122:Zfp318
|
UTSW |
17 |
46,724,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2339:Zfp318
|
UTSW |
17 |
46,710,389 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4526:Zfp318
|
UTSW |
17 |
46,723,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4564:Zfp318
|
UTSW |
17 |
46,723,741 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4689:Zfp318
|
UTSW |
17 |
46,710,560 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4795:Zfp318
|
UTSW |
17 |
46,722,988 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5256:Zfp318
|
UTSW |
17 |
46,722,995 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5317:Zfp318
|
UTSW |
17 |
46,723,463 (GRCm39) |
unclassified |
probably benign |
|
|
R5323:Zfp318
|
UTSW |
17 |
46,697,662 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5436:Zfp318
|
UTSW |
17 |
46,723,975 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5485:Zfp318
|
UTSW |
17 |
46,723,180 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5627:Zfp318
|
UTSW |
17 |
46,724,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5643:Zfp318
|
UTSW |
17 |
46,720,170 (GRCm39) |
intron |
probably benign |
|
|
R5782:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R5783:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R5820:Zfp318
|
UTSW |
17 |
46,723,699 (GRCm39) |
missense |
probably benign |
|
|
R5895:Zfp318
|
UTSW |
17 |
46,709,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R6385:Zfp318
|
UTSW |
17 |
46,721,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Zfp318
|
UTSW |
17 |
46,710,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Zfp318
|
UTSW |
17 |
46,710,431 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6666:Zfp318
|
UTSW |
17 |
46,720,140 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6812:Zfp318
|
UTSW |
17 |
46,723,468 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,464 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,459 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,460 (GRCm39) |
unclassified |
probably benign |
|
|
R6854:Zfp318
|
UTSW |
17 |
46,723,468 (GRCm39) |
unclassified |
probably benign |
|
|
R6980:Zfp318
|
UTSW |
17 |
46,708,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6999:Zfp318
|
UTSW |
17 |
46,710,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7164:Zfp318
|
UTSW |
17 |
46,716,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7164:Zfp318
|
UTSW |
17 |
46,708,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7175:Zfp318
|
UTSW |
17 |
46,697,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7233:Zfp318
|
UTSW |
17 |
46,716,978 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7339:Zfp318
|
UTSW |
17 |
46,722,173 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7426:Zfp318
|
UTSW |
17 |
46,710,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7600:Zfp318
|
UTSW |
17 |
46,695,210 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7608:Zfp318
|
UTSW |
17 |
46,710,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7779:Zfp318
|
UTSW |
17 |
46,710,820 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8057:Zfp318
|
UTSW |
17 |
46,710,692 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R8273:Zfp318
|
UTSW |
17 |
46,723,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8274:Zfp318
|
UTSW |
17 |
46,723,915 (GRCm39) |
missense |
probably benign |
|
|
R8695:Zfp318
|
UTSW |
17 |
46,723,576 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8822:Zfp318
|
UTSW |
17 |
46,723,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8851:Zfp318
|
UTSW |
17 |
46,710,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Zfp318
|
UTSW |
17 |
46,722,699 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8953:Zfp318
|
UTSW |
17 |
46,731,356 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9031:Zfp318
|
UTSW |
17 |
46,723,433 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9327:Zfp318
|
UTSW |
17 |
46,721,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9329:Zfp318
|
UTSW |
17 |
46,722,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9352:Zfp318
|
UTSW |
17 |
46,721,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9633:Zfp318
|
UTSW |
17 |
46,710,421 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9662:Zfp318
|
UTSW |
17 |
46,724,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9728:Zfp318
|
UTSW |
17 |
46,707,713 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9755:Zfp318
|
UTSW |
17 |
46,722,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Zfp318
|
UTSW |
17 |
46,721,564 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
X0054:Zfp318
|
UTSW |
17 |
46,723,535 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
X0065:Zfp318
|
UTSW |
17 |
46,721,915 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Zfp318
|
UTSW |
17 |
46,716,904 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGCTTGTGACATTTCATGACACTG -3'
(R):5'- TTCGCTGCCGATAGTTTCGAGTCC -3'
Sequencing Primer
(F):5'- TGACATTTCATGACACTGAGAAAGG -3'
(R):5'- CCGATAGTTTCGAGTCCCAGATG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation