Mutagenetix > Incidental Mutation

Incidental Mutation 'R5205:Chd7'

398409

Institutional Source

Beutler Lab

Gene Symbol

Chd7

Ensembl Gene

ENSMUSG00000041235

Gene Name

chromodomain helicase DNA binding protein 7

Synonyms

Whi, Dz, Cyn, GENA 47, Cycn, Lda, Flo, Obt, Edy, A730019I05Rik, Todo, GENA 60, WBE1, Gena 52, Mt

MMRRC Submission

042780-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.952) question?

Stock #

R5205 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

8690406-8867659 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 8752509 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 335 (N335K)

Ref Sequence

ENSEMBL: ENSMUSP00000118711 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039267] [ENSMUST00000051558] [ENSMUST00000127476] [ENSMUST00000129655] [ENSMUST00000170391]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000039267
AA Change: N335K

SMART Domains

Protein: ENSMUSP00000043903
Gene: ENSMUSG00000041235
AA Change: N335K

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
low complexity region	585	595	N/A	INTRINSIC
low complexity region	632	696	N/A	INTRINSIC
low complexity region	721	733	N/A	INTRINSIC
low complexity region	735	748	N/A	INTRINSIC
low complexity region	759	768	N/A	INTRINSIC
CHROMO	789	854	2.54e-9	SMART
CHROMO	870	927	2.94e-5	SMART
low complexity region	928	939	N/A	INTRINSIC
DEXDc	954	1155	9.64e-38	SMART
HELICc	1310	1394	1.67e-23	SMART
Blast:DEXDc	1608	1653	8e-16	BLAST
low complexity region	1728	1739	N/A	INTRINSIC
internal_repeat_2	1774	1825	1.31e-5	PROSPERO
low complexity region	1831	1846	N/A	INTRINSIC
low complexity region	1898	1906	N/A	INTRINSIC
low complexity region	1929	1947	N/A	INTRINSIC
SANT	1952	2011	9.31e-1	SMART
internal_repeat_2	2079	2126	1.31e-5	PROSPERO
low complexity region	2173	2195	N/A	INTRINSIC
low complexity region	2218	2244	N/A	INTRINSIC
low complexity region	2387	2407	N/A	INTRINSIC
low complexity region	2437	2452	N/A	INTRINSIC
BRK	2553	2602	6.57e-23	SMART
BRK	2631	2675	3.77e-23	SMART
low complexity region	2715	2725	N/A	INTRINSIC
low complexity region	2746	2758	N/A	INTRINSIC
low complexity region	2769	2778	N/A	INTRINSIC
low complexity region	2785	2796	N/A	INTRINSIC
low complexity region	2810	2821	N/A	INTRINSIC
low complexity region	2897	2916	N/A	INTRINSIC
low complexity region	2967	2980	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000051558
AA Change: N335K

SMART Domains

Protein: ENSMUSP00000059079
Gene: ENSMUSG00000041235
AA Change: N335K

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
low complexity region	585	595	N/A	INTRINSIC
low complexity region	632	696	N/A	INTRINSIC
low complexity region	721	733	N/A	INTRINSIC
low complexity region	735	748	N/A	INTRINSIC
low complexity region	759	768	N/A	INTRINSIC
CHROMO	789	854	2.54e-9	SMART
CHROMO	870	927	2.94e-5	SMART
low complexity region	928	939	N/A	INTRINSIC
DEXDc	954	1155	9.64e-38	SMART
HELICc	1310	1394	1.67e-23	SMART
Blast:DEXDc	1608	1653	8e-16	BLAST
low complexity region	1728	1739	N/A	INTRINSIC
internal_repeat_2	1774	1825	1.31e-5	PROSPERO
low complexity region	1831	1846	N/A	INTRINSIC
low complexity region	1898	1906	N/A	INTRINSIC
low complexity region	1929	1947	N/A	INTRINSIC
SANT	1952	2011	9.31e-1	SMART
internal_repeat_2	2079	2126	1.31e-5	PROSPERO
low complexity region	2173	2195	N/A	INTRINSIC
low complexity region	2218	2244	N/A	INTRINSIC
low complexity region	2387	2407	N/A	INTRINSIC
low complexity region	2437	2452	N/A	INTRINSIC
BRK	2553	2602	6.57e-23	SMART
BRK	2631	2675	3.77e-23	SMART
low complexity region	2715	2725	N/A	INTRINSIC
low complexity region	2746	2758	N/A	INTRINSIC
low complexity region	2769	2778	N/A	INTRINSIC
low complexity region	2785	2796	N/A	INTRINSIC
low complexity region	2810	2821	N/A	INTRINSIC
low complexity region	2897	2916	N/A	INTRINSIC
low complexity region	2967	2980	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000127476
AA Change: N335K

PolyPhen 2 Score 0.601 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000118711
Gene: ENSMUSG00000041235
AA Change: N335K

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
low complexity region	585	595	N/A	INTRINSIC
Blast:CHROMO	596	630	6e-8	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000129655

Predicted Effect

unknown
Transcript: ENSMUST00000170391
AA Change: N335K

SMART Domains

Protein: ENSMUSP00000127007
Gene: ENSMUSG00000041235
AA Change: N335K

Domain	Start	End	E-Value	Type
low complexity region	11	28	N/A	INTRINSIC
low complexity region	48	59	N/A	INTRINSIC
low complexity region	107	129	N/A	INTRINSIC
low complexity region	152	178	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	385	400	N/A	INTRINSIC
low complexity region	491	504	N/A	INTRINSIC
low complexity region	512	535	N/A	INTRINSIC
BRK	586	630	3.77e-23	SMART
low complexity region	670	680	N/A	INTRINSIC
low complexity region	701	713	N/A	INTRINSIC
low complexity region	724	733	N/A	INTRINSIC
low complexity region	740	751	N/A	INTRINSIC
low complexity region	765	776	N/A	INTRINSIC
low complexity region	852	871	N/A	INTRINSIC
low complexity region	922	935	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000170457

Meta Mutation Damage Score

0.0690

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.1%
20x: 95.0%

Validation Efficiency

100% (54/54)

MGI Phenotype

FUNCTION: This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]
PHENOTYPE: Heterozygotes for mutations of this gene exhibit a variety of combinations of hyperactivity, circling, head-bobbing, semicircular canal defects, hearing loss, reduced size, and tail-kink. [provided by MGI curators]

Allele List at MGI

All alleles(32) : Targeted, other(4) Gene trapped(19) Chemically induced(9)

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts19	G	A	18: 59,101,880 (GRCm39)	R650Q	probably damaging	Het
Adgre4	G	T	17: 56,101,727 (GRCm39)	E216*	probably null	Het
Aldh6a1	T	A	12: 84,486,418 (GRCm39)	M167L	probably damaging	Het
Asb16	G	A	11: 102,159,820 (GRCm39)	D58N	probably damaging	Het
Cfap43	C	A	19: 47,885,987 (GRCm39)	L209F	possibly damaging	Het
Cfh	A	G	1: 140,071,708 (GRCm39)	C327R	probably damaging	Het
Clca3a1	T	C	3: 144,452,545 (GRCm39)	E646G	possibly damaging	Het
Col6a6	A	T	9: 105,659,232 (GRCm39)	V571D	probably damaging	Het
Cttnbp2	T	C	6: 18,427,432 (GRCm39)		probably benign	Het
Dennd1b	T	A	1: 138,982,306 (GRCm39)	S132T	probably benign	Het
Dmpk	C	G	7: 18,821,944 (GRCm39)	L301V	probably benign	Het
Dnaaf2	C	T	12: 69,239,698 (GRCm39)	V608I	probably damaging	Het
Edem3	A	T	1: 151,687,270 (GRCm39)	D717V	probably damaging	Het
Fam135a	T	C	1: 24,068,592 (GRCm39)	N589S	probably benign	Het
Gm13991	G	C	2: 116,358,681 (GRCm39)		noncoding transcript	Het
Ighv2-3	T	C	12: 113,574,895 (GRCm39)	S87G	probably benign	Het
Igkv4-80	A	C	6: 68,993,649 (GRCm39)	S81A	probably benign	Het
Kcna2	T	C	3: 107,004,462 (GRCm39)		probably benign	Het
Klra4	T	A	6: 130,039,080 (GRCm39)	N104I	probably damaging	Het
Lrrc28	A	G	7: 67,181,516 (GRCm39)	S240P	probably benign	Het
Majin	T	C	19: 6,245,789 (GRCm39)	I27T	possibly damaging	Het
Mfhas1	G	A	8: 36,058,161 (GRCm39)	E879K	probably benign	Het
Mif-ps6	A	T	9: 14,756,768 (GRCm39)		noncoding transcript	Het
Msh4	A	G	3: 153,572,049 (GRCm39)	L583P	probably damaging	Het
Nrxn1	A	T	17: 90,471,302 (GRCm39)	N1234K	probably damaging	Het
Or5b120	T	C	19: 13,480,163 (GRCm39)	L152P	probably damaging	Het
Orm1	T	C	4: 63,262,929 (GRCm39)	I32T	possibly damaging	Het
Otx1	C	A	11: 21,947,037 (GRCm39)	A91S	probably damaging	Het
Plppr2	A	T	9: 21,852,370 (GRCm39)	T85S	probably damaging	Het
Ppp1r9b	T	A	11: 94,892,124 (GRCm39)	W604R	probably benign	Het
Prorp	T	A	12: 55,351,226 (GRCm39)	Y178*	probably null	Het
Prss56	G	T	1: 87,113,256 (GRCm39)	D195Y	probably damaging	Het
Psme4	T	A	11: 30,782,666 (GRCm39)		probably benign	Het
Rbm25	T	A	12: 83,719,643 (GRCm39)	D554E	probably benign	Het
Rbm6	A	G	9: 107,665,542 (GRCm39)	M618T	probably benign	Het
Slc17a5	A	G	9: 78,485,899 (GRCm39)	V62A	probably damaging	Het
Slk	T	A	19: 47,613,899 (GRCm39)	N918K	possibly damaging	Het
Syne1	C	A	10: 5,002,295 (GRCm39)	A8126S	probably benign	Het
Synj2	T	C	17: 5,991,793 (GRCm39)	L23S	probably damaging	Het
Taar2	A	C	10: 23,816,874 (GRCm39)	H138P	probably benign	Het
Taar7b	A	T	10: 23,875,916 (GRCm39)	E27V	probably benign	Het
Tbc1d2b	A	G	9: 90,089,863 (GRCm39)	Y889H	probably damaging	Het
Tmem43	T	C	6: 91,463,763 (GRCm39)	I346T	possibly damaging	Het
Ttc3	T	A	16: 94,248,918 (GRCm39)	C1139S	probably benign	Het
Txndc11	A	G	16: 10,946,529 (GRCm39)	V94A	probably damaging	Het
Ush2a	T	A	1: 188,607,133 (GRCm39)	H4009Q	probably benign	Het
Wnk4	A	G	11: 101,155,964 (GRCm39)	E407G	possibly damaging	Het
Ybx1	G	T	4: 119,136,348 (GRCm39)	D261E	probably damaging	Het
Zfp985	A	T	4: 147,667,368 (GRCm39)	I79F	probably damaging	Het

Other mutations in Chd7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00422:Chd7	APN	4	8,859,106 (GRCm39)	missense	probably damaging	1.00
IGL00510:Chd7	APN	4	8,801,404 (GRCm39)	missense	probably damaging	1.00
IGL00741:Chd7	APN	4	8,839,454 (GRCm39)	missense	probably damaging	1.00
IGL00796:Chd7	APN	4	8,847,271 (GRCm39)	missense	possibly damaging	0.95
IGL00907:Chd7	APN	4	8,840,435 (GRCm39)	missense	probably damaging	0.98
IGL00930:Chd7	APN	4	8,805,181 (GRCm39)	missense	probably damaging	1.00
IGL01542:Chd7	APN	4	8,859,285 (GRCm39)	missense	possibly damaging	0.71
IGL01602:Chd7	APN	4	8,833,834 (GRCm39)	missense	probably damaging	1.00
IGL01605:Chd7	APN	4	8,833,834 (GRCm39)	missense	probably damaging	1.00
IGL01670:Chd7	APN	4	8,827,033 (GRCm39)	missense	probably damaging	0.98
IGL02434:Chd7	APN	4	8,752,145 (GRCm39)	missense	probably benign	0.00
IGL02531:Chd7	APN	4	8,854,134 (GRCm39)	missense	probably damaging	1.00
IGL02626:Chd7	APN	4	8,826,519 (GRCm39)	missense	probably damaging	1.00
IGL02961:Chd7	APN	4	8,751,542 (GRCm39)	missense	probably damaging	1.00
IGL02972:Chd7	APN	4	8,855,174 (GRCm39)	missense	probably benign	0.30
IGL03329:Chd7	APN	4	8,841,108 (GRCm39)	missense	probably damaging	1.00
Fili	UTSW	4	8,839,523 (GRCm39)	missense	probably damaging	1.00
D4043:Chd7	UTSW	4	8,862,650 (GRCm39)	missense	probably damaging	1.00
IGL02991:Chd7	UTSW	4	8,828,398 (GRCm39)	missense	possibly damaging	0.91
PIT4466001:Chd7	UTSW	4	8,753,101 (GRCm39)	missense	unknown
PIT4472001:Chd7	UTSW	4	8,753,101 (GRCm39)	missense	unknown
R0157:Chd7	UTSW	4	8,833,759 (GRCm39)	missense	probably damaging	1.00
R0179:Chd7	UTSW	4	8,862,516 (GRCm39)	missense	probably benign	0.22
R0240:Chd7	UTSW	4	8,852,670 (GRCm39)	unclassified	probably benign
R0388:Chd7	UTSW	4	8,854,560 (GRCm39)	missense	probably benign	0.27
R0462:Chd7	UTSW	4	8,850,821 (GRCm39)	missense	probably damaging	1.00
R0512:Chd7	UTSW	4	8,805,139 (GRCm39)	intron	probably benign
R0657:Chd7	UTSW	4	8,753,141 (GRCm39)	missense	probably damaging	1.00
R0799:Chd7	UTSW	4	8,801,310 (GRCm39)	intron	probably benign
R0885:Chd7	UTSW	4	8,866,432 (GRCm39)	missense	probably damaging	1.00
R1056:Chd7	UTSW	4	8,822,402 (GRCm39)	missense	possibly damaging	0.50
R1086:Chd7	UTSW	4	8,866,458 (GRCm39)	missense	probably benign	0.04
R1353:Chd7	UTSW	4	8,839,556 (GRCm39)	missense	probably damaging	0.99
R1466:Chd7	UTSW	4	8,840,561 (GRCm39)	splice site	probably null
R1466:Chd7	UTSW	4	8,840,561 (GRCm39)	splice site	probably null
R1605:Chd7	UTSW	4	8,844,675 (GRCm39)	missense	probably damaging	1.00
R1693:Chd7	UTSW	4	8,864,307 (GRCm39)	critical splice donor site	probably null
R1695:Chd7	UTSW	4	8,833,960 (GRCm39)	missense	probably damaging	1.00
R1938:Chd7	UTSW	4	8,847,200 (GRCm39)	missense	probably damaging	1.00
R1964:Chd7	UTSW	4	8,865,978 (GRCm39)	missense	probably damaging	0.96
R2020:Chd7	UTSW	4	8,855,226 (GRCm39)	missense	probably benign	0.00
R2134:Chd7	UTSW	4	8,753,147 (GRCm39)	missense	probably damaging	0.99
R2171:Chd7	UTSW	4	8,752,424 (GRCm39)	missense	probably damaging	1.00
R2271:Chd7	UTSW	4	8,785,532 (GRCm39)	missense	probably damaging	1.00
R2300:Chd7	UTSW	4	8,855,241 (GRCm39)	missense	probably benign	0.02
R2355:Chd7	UTSW	4	8,801,350 (GRCm39)	missense	possibly damaging	0.95
R3153:Chd7	UTSW	4	8,855,174 (GRCm39)	missense	probably benign	0.30
R3430:Chd7	UTSW	4	8,844,517 (GRCm39)	missense	probably damaging	0.99
R3746:Chd7	UTSW	4	8,752,537 (GRCm39)	missense	probably damaging	1.00
R4118:Chd7	UTSW	4	8,865,831 (GRCm39)	missense	probably damaging	1.00
R4119:Chd7	UTSW	4	8,785,658 (GRCm39)	intron	probably benign
R4332:Chd7	UTSW	4	8,854,143 (GRCm39)	missense	probably damaging	1.00
R4402:Chd7	UTSW	4	8,866,353 (GRCm39)	missense	possibly damaging	0.61
R4571:Chd7	UTSW	4	8,866,217 (GRCm39)	missense	probably benign	0.09
R4722:Chd7	UTSW	4	8,822,445 (GRCm39)	missense	probably damaging	1.00
R4821:Chd7	UTSW	4	8,844,706 (GRCm39)	missense	probably damaging	1.00
R4894:Chd7	UTSW	4	8,838,629 (GRCm39)	missense	probably damaging	0.99
R5344:Chd7	UTSW	4	8,844,417 (GRCm39)	missense	probably damaging	1.00
R5484:Chd7	UTSW	4	8,828,258 (GRCm39)	missense	probably damaging	1.00
R5578:Chd7	UTSW	4	8,847,149 (GRCm39)	missense	probably benign	0.09
R5583:Chd7	UTSW	4	8,752,473 (GRCm39)	missense	probably damaging	1.00
R5888:Chd7	UTSW	4	8,866,382 (GRCm39)	missense	probably damaging	0.98
R5905:Chd7	UTSW	4	8,840,553 (GRCm39)	missense	possibly damaging	0.91
R6091:Chd7	UTSW	4	8,751,875 (GRCm39)	missense	probably damaging	0.99
R6126:Chd7	UTSW	4	8,826,482 (GRCm39)	missense	probably damaging	1.00
R6399:Chd7	UTSW	4	8,828,274 (GRCm39)	missense	probably damaging	1.00
R6751:Chd7	UTSW	4	8,833,866 (GRCm39)	missense	probably damaging	1.00
R6810:Chd7	UTSW	4	8,839,523 (GRCm39)	missense	probably damaging	1.00
R6868:Chd7	UTSW	4	8,811,501 (GRCm39)	splice site	probably null
R6952:Chd7	UTSW	4	8,856,797 (GRCm39)	missense	probably damaging	1.00
R6986:Chd7	UTSW	4	8,859,285 (GRCm39)	missense	possibly damaging	0.71
R6990:Chd7	UTSW	4	8,844,525 (GRCm39)	missense	probably benign	0.28
R7139:Chd7	UTSW	4	8,865,865 (GRCm39)	missense	probably benign	0.00
R7288:Chd7	UTSW	4	8,847,093 (GRCm39)	missense	possibly damaging	0.92
R7355:Chd7	UTSW	4	8,752,196 (GRCm39)	missense	unknown
R7452:Chd7	UTSW	4	8,854,731 (GRCm39)	missense	probably benign	0.03
R7471:Chd7	UTSW	4	8,859,197 (GRCm39)	missense	probably damaging	0.96
R7588:Chd7	UTSW	4	8,864,039 (GRCm39)	missense	probably damaging	1.00
R7711:Chd7	UTSW	4	8,805,234 (GRCm39)	missense	probably benign	0.00
R7744:Chd7	UTSW	4	8,862,485 (GRCm39)	splice site	probably null
R7842:Chd7	UTSW	4	8,854,115 (GRCm39)	missense	probably benign	0.01
R7883:Chd7	UTSW	4	8,826,504 (GRCm39)	missense	probably damaging	1.00
R7934:Chd7	UTSW	4	8,854,121 (GRCm39)	missense	probably benign	0.00
R7983:Chd7	UTSW	4	8,844,609 (GRCm39)	missense	possibly damaging	0.47
R7983:Chd7	UTSW	4	8,752,628 (GRCm39)	missense	unknown
R8022:Chd7	UTSW	4	8,751,605 (GRCm39)	missense	unknown
R8161:Chd7	UTSW	4	8,855,038 (GRCm39)	missense	probably damaging	1.00
R8274:Chd7	UTSW	4	8,839,432 (GRCm39)	missense	probably damaging	1.00
R8278:Chd7	UTSW	4	8,862,485 (GRCm39)	splice site	probably null
R8358:Chd7	UTSW	4	8,839,529 (GRCm39)	missense	probably damaging	1.00
R8464:Chd7	UTSW	4	8,811,465 (GRCm39)	missense	probably benign	0.06
R8483:Chd7	UTSW	4	8,822,412 (GRCm39)	missense	possibly damaging	0.65
R8507:Chd7	UTSW	4	8,858,675 (GRCm39)	missense	probably damaging	1.00
R8535:Chd7	UTSW	4	8,859,211 (GRCm39)	missense	possibly damaging	0.92
R8695:Chd7	UTSW	4	8,850,812 (GRCm39)	missense	probably damaging	1.00
R8700:Chd7	UTSW	4	8,833,892 (GRCm39)	missense	probably damaging	1.00
R8755:Chd7	UTSW	4	8,866,069 (GRCm39)	missense	probably benign	0.31
R8774:Chd7	UTSW	4	8,854,692 (GRCm39)	missense	probably damaging	1.00
R8774-TAIL:Chd7	UTSW	4	8,854,692 (GRCm39)	missense	probably damaging	1.00
R8796:Chd7	UTSW	4	8,838,691 (GRCm39)	missense	probably damaging	1.00
R8992:Chd7	UTSW	4	8,839,589 (GRCm39)	missense	probably damaging	1.00
R9018:Chd7	UTSW	4	8,847,083 (GRCm39)	missense	possibly damaging	0.88
R9122:Chd7	UTSW	4	8,840,510 (GRCm39)	missense	possibly damaging	0.77
R9131:Chd7	UTSW	4	8,785,642 (GRCm39)	missense
R9182:Chd7	UTSW	4	8,838,737 (GRCm39)	missense	probably damaging	1.00
R9227:Chd7	UTSW	4	8,805,272 (GRCm39)	missense	probably benign	0.03
R9254:Chd7	UTSW	4	8,752,210 (GRCm39)	missense	unknown
R9379:Chd7	UTSW	4	8,752,210 (GRCm39)	missense	unknown
R9388:Chd7	UTSW	4	8,865,756 (GRCm39)	missense	possibly damaging	0.89
R9455:Chd7	UTSW	4	8,752,061 (GRCm39)	missense	unknown
R9531:Chd7	UTSW	4	8,858,489 (GRCm39)	missense
R9577:Chd7	UTSW	4	8,752,964 (GRCm39)	missense	unknown
R9634:Chd7	UTSW	4	8,832,499 (GRCm39)	missense	probably damaging	1.00
Z1176:Chd7	UTSW	4	8,844,313 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTGCCCACAGTCCCAGATTC -3'
(R):5'- TACTCATTGCTTTCATGGGTGAC -3'

Sequencing Primer
(F):5'- TCCTCAACAAGGGGCTGTCAG -3'
(R):5'- ATGGGTGACATGGGAGGTG -3'

Posted On

2016-07-06