Mutagenetix > Incidental Mutation

Incidental Mutation 'R5248:Ptprz1'

398644

Institutional Source

Beutler Lab

Gene Symbol

Ptprz1

Ensembl Gene

ENSMUSG00000068748

Gene Name

protein tyrosine phosphatase receptor type Z, polypeptide 1

Synonyms

DSD-1-PG, phosphacan, Ptprz, Ptpz, PTPzeta, Rptpbeta, RPTPz, PTPbeta

MMRRC Submission

042819-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.726) question?

Stock #

R5248 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

22875501-23052915 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 23001900 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Glutamine at position 1330 (P1330Q)

Ref Sequence

ENSEMBL: ENSMUSP00000144605 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090568] [ENSMUST00000202102] [ENSMUST00000202579]

AlphaFold

B9EKR1

Predicted Effect

probably benign
Transcript: ENSMUST00000090568
AA Change: P1330Q

PolyPhen 2 Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000088056
Gene: ENSMUSG00000068748
AA Change: P1330Q

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC
Blast:PTPc	1497	1573	1e-12	BLAST
low complexity region	1606	1620	N/A	INTRINSIC
transmembrane domain	1637	1659	N/A	INTRINSIC
low complexity region	1679	1693	N/A	INTRINSIC
PTPc	1720	1991	2.8e-130	SMART
PTPc	2019	2281	1.65e-77	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000201827

Predicted Effect

probably benign
Transcript: ENSMUST00000202102

SMART Domains

Protein: ENSMUSP00000143902
Gene: ENSMUSG00000068748

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
transmembrane domain	788	810	N/A	INTRINSIC
low complexity region	830	844	N/A	INTRINSIC
PTPc	871	1142	2.8e-130	SMART
PTPc	1170	1432	1.65e-77	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000202579
AA Change: P1330Q

PolyPhen 2 Score 0.107 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000144605
Gene: ENSMUSG00000068748
AA Change: P1330Q

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Carb_anhydrase	38	300	4e-103	SMART
FN3	312	397	2.8e-6	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.1%
20x: 94.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
PHENOTYPE: Mice homozygous for targeted null mutations demonstrate an impaired ability to recover from inflamatory lesions of the CNS or gastric mucosa. Mice homozygous for a knock-out allele exhibit increased tactile and thermal nociception thresholds. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aass	T	A	6: 23,109,437 (GRCm39)	E344D	probably benign	Het
Acoxl	G	A	2: 127,917,855 (GRCm39)		probably null	Het
Adora1	A	T	1: 134,131,224 (GRCm39)	L149Q	possibly damaging	Het
Aebp1	C	A	11: 5,818,501 (GRCm39)	D115E	possibly damaging	Het
Ank3	A	G	10: 69,822,938 (GRCm39)	I1819V	probably benign	Het
Ankrd44	T	C	1: 54,706,539 (GRCm39)	H454R	probably damaging	Het
Ap4e1	C	T	2: 126,906,842 (GRCm39)	A1034V	possibly damaging	Het
B3galt2	T	A	1: 143,522,849 (GRCm39)	F328L	probably benign	Het
Bbip1	G	A	19: 53,919,786 (GRCm39)		probably benign	Het
Brsk1	G	A	7: 4,711,865 (GRCm39)	E572K	possibly damaging	Het
Clca3a1	G	T	3: 144,442,897 (GRCm39)	P716T	possibly damaging	Het
Clpx	T	C	9: 65,228,132 (GRCm39)	V380A	probably damaging	Het
Epha3	T	A	16: 63,418,620 (GRCm39)	Q608H	probably damaging	Het
Gprc6a	G	T	10: 51,491,089 (GRCm39)	P712T	probably damaging	Het
Itpr1	C	A	6: 108,519,023 (GRCm39)	Q2720K	probably damaging	Het
Kdm5b	A	G	1: 134,548,735 (GRCm39)	E1080G	probably benign	Het
Macf1	G	A	4: 123,295,567 (GRCm39)	R3163*	probably null	Het
Map4k5	T	C	12: 69,888,755 (GRCm39)	D292G	probably benign	Het
Mau2	A	T	8: 70,481,373 (GRCm39)	C217S	probably benign	Het
Mtf1	T	C	4: 124,714,220 (GRCm39)	F210L	probably damaging	Het
Mtif2	G	A	11: 29,486,889 (GRCm39)	V300M	probably damaging	Het
Mtmr2	T	C	9: 13,694,905 (GRCm39)		probably benign	Het
Mybpc3	C	A	2: 90,955,573 (GRCm39)		probably null	Het
Ncmap	T	C	4: 135,107,430 (GRCm39)		probably null	Het
Nek9	A	G	12: 85,355,751 (GRCm39)	F672S	probably damaging	Het
Nuak1	A	T	10: 84,245,542 (GRCm39)	I101N	probably damaging	Het
Or8s16	T	C	15: 98,211,311 (GRCm39)	N40S	probably damaging	Het
Pcdh7	T	A	5: 58,286,515 (GRCm39)	M1197K	probably damaging	Het
Pcdhb17	A	C	18: 37,618,939 (GRCm39)	Q243P	probably benign	Het
Pcf11	T	G	7: 92,310,699 (GRCm39)	K221Q	probably damaging	Het
Pkhd1	C	T	1: 20,604,769 (GRCm39)	R1182H	probably benign	Het
Rbm33	T	G	5: 28,542,050 (GRCm39)		probably null	Het
Rhobtb1	A	G	10: 69,084,615 (GRCm39)	D2G	probably damaging	Het
Rngtt	T	A	4: 33,325,110 (GRCm39)	C110*	probably null	Het
Setx	T	A	2: 29,038,430 (GRCm39)	N1638K	probably benign	Het
Slc24a3	A	T	2: 145,446,437 (GRCm39)	M282L	probably benign	Het
Slc7a1	A	T	5: 148,270,798 (GRCm39)	V556D	possibly damaging	Het
Sppl2c	A	T	11: 104,077,407 (GRCm39)	D69V	possibly damaging	Het
Srpk3	C	T	X: 72,818,555 (GRCm39)	R82*	probably null	Het
Tas2r120	A	T	6: 132,634,110 (GRCm39)	N64I	probably damaging	Het
Tcf25	G	T	8: 124,100,678 (GRCm39)	A23S	probably damaging	Het
Tigd2	A	T	6: 59,188,138 (GRCm39)	K335I	probably damaging	Het
Tlr6	A	G	5: 65,112,647 (GRCm39)	S87P	probably benign	Het
Tmem135	T	A	7: 88,797,200 (GRCm39)	Y352F	probably damaging	Het
Tob2	T	C	15: 81,735,918 (GRCm39)	Y17C	probably damaging	Het
Tymp	GC	GCC	15: 89,258,567 (GRCm39)		probably null	Het
Vmn1r179	T	C	7: 23,628,478 (GRCm39)	V223A	probably damaging	Het
Zfp946	T	C	17: 22,673,447 (GRCm39)	V67A	probably benign	Het
Zswim4	G	T	8: 84,946,561 (GRCm39)	N698K	probably benign	Het
Zzz3	A	G	3: 152,133,182 (GRCm39)	Q80R	probably damaging	Het

Other mutations in Ptprz1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00486:Ptprz1	APN	6	22,973,053 (GRCm39)	missense	probably damaging	1.00
IGL00773:Ptprz1	APN	6	23,002,628 (GRCm39)	missense	probably benign	0.41
IGL01458:Ptprz1	APN	6	22,972,843 (GRCm39)	missense	probably damaging	0.99
IGL01481:Ptprz1	APN	6	22,999,979 (GRCm39)	missense	probably benign	0.05
IGL01501:Ptprz1	APN	6	22,973,081 (GRCm39)	missense	probably damaging	1.00
IGL01601:Ptprz1	APN	6	23,000,437 (GRCm39)	missense	probably damaging	0.99
IGL01882:Ptprz1	APN	6	23,000,463 (GRCm39)	missense	probably damaging	1.00
IGL02058:Ptprz1	APN	6	23,002,502 (GRCm39)	missense	probably benign	0.00
IGL02089:Ptprz1	APN	6	23,033,447 (GRCm39)	missense	probably damaging	1.00
IGL02136:Ptprz1	APN	6	22,972,821 (GRCm39)	missense	probably damaging	1.00
IGL02215:Ptprz1	APN	6	22,965,181 (GRCm39)	missense	possibly damaging	0.91
IGL02220:Ptprz1	APN	6	23,042,742 (GRCm39)	splice site	probably benign
IGL02556:Ptprz1	APN	6	22,972,844 (GRCm39)	missense	probably benign	0.01
IGL02601:Ptprz1	APN	6	23,000,686 (GRCm39)	missense	probably benign	0.11
IGL02620:Ptprz1	APN	6	22,959,739 (GRCm39)	missense	probably damaging	1.00
IGL02666:Ptprz1	APN	6	23,001,209 (GRCm39)	missense	probably benign	0.00
IGL02718:Ptprz1	APN	6	23,001,348 (GRCm39)	missense	possibly damaging	0.77
IGL02792:Ptprz1	APN	6	22,959,722 (GRCm39)	missense	probably damaging	1.00
IGL02894:Ptprz1	APN	6	23,035,148 (GRCm39)	missense	probably damaging	1.00
IGL02952:Ptprz1	APN	6	23,036,925 (GRCm39)	missense	probably damaging	1.00
IGL03003:Ptprz1	APN	6	23,002,582 (GRCm39)	missense	probably damaging	0.98
IGL03060:Ptprz1	APN	6	22,972,834 (GRCm39)	missense	probably damaging	1.00
IGL03170:Ptprz1	APN	6	22,959,766 (GRCm39)	missense	probably benign	0.00
IGL03246:Ptprz1	APN	6	22,986,159 (GRCm39)	missense	probably damaging	0.99
IGL03349:Ptprz1	APN	6	23,000,331 (GRCm39)	missense	probably damaging	1.00
IGL03365:Ptprz1	APN	6	23,030,581 (GRCm39)	splice site	probably benign
Elevator	UTSW	6	23,030,661 (GRCm39)	missense	probably benign	0.03
escalator	UTSW	6	22,986,187 (GRCm39)	missense	probably damaging	1.00
R0044:Ptprz1	UTSW	6	23,007,402 (GRCm39)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,195 (GRCm39)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,195 (GRCm39)	missense	probably damaging	1.00
R0107:Ptprz1	UTSW	6	23,000,569 (GRCm39)	missense	probably damaging	0.98
R0278:Ptprz1	UTSW	6	23,000,816 (GRCm39)	missense	probably benign	0.31
R0345:Ptprz1	UTSW	6	23,016,164 (GRCm39)	missense	probably damaging	1.00
R0359:Ptprz1	UTSW	6	22,973,175 (GRCm39)	splice site	probably benign
R0743:Ptprz1	UTSW	6	23,044,366 (GRCm39)	nonsense	probably null
R1014:Ptprz1	UTSW	6	23,000,643 (GRCm39)	missense	probably damaging	1.00
R1016:Ptprz1	UTSW	6	23,000,973 (GRCm39)	missense	probably damaging	1.00
R1106:Ptprz1	UTSW	6	22,965,748 (GRCm39)	missense	probably damaging	0.99
R1391:Ptprz1	UTSW	6	23,001,728 (GRCm39)	missense	probably benign	0.33
R1424:Ptprz1	UTSW	6	23,000,382 (GRCm39)	missense	probably benign	0.00
R1445:Ptprz1	UTSW	6	23,050,473 (GRCm39)	missense	probably damaging	1.00
R1496:Ptprz1	UTSW	6	23,049,523 (GRCm39)	splice site	probably benign
R1544:Ptprz1	UTSW	6	23,000,747 (GRCm39)	missense	possibly damaging	0.63
R1626:Ptprz1	UTSW	6	23,001,573 (GRCm39)	missense	probably benign
R1641:Ptprz1	UTSW	6	23,049,605 (GRCm39)	missense	probably damaging	1.00
R1757:Ptprz1	UTSW	6	23,044,319 (GRCm39)	missense	probably damaging	1.00
R1812:Ptprz1	UTSW	6	22,959,711 (GRCm39)	missense	probably benign	0.07
R1917:Ptprz1	UTSW	6	23,035,039 (GRCm39)	splice site	probably benign
R1930:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R1931:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R1974:Ptprz1	UTSW	6	22,986,310 (GRCm39)	missense	probably damaging	1.00
R1992:Ptprz1	UTSW	6	22,959,747 (GRCm39)	missense	probably benign	0.24
R1997:Ptprz1	UTSW	6	23,050,496 (GRCm39)	missense	probably damaging	0.99
R2002:Ptprz1	UTSW	6	23,027,833 (GRCm39)	nonsense	probably null
R2012:Ptprz1	UTSW	6	23,001,026 (GRCm39)	missense	probably benign	0.03
R2059:Ptprz1	UTSW	6	22,986,322 (GRCm39)	splice site	probably benign
R2061:Ptprz1	UTSW	6	23,049,674 (GRCm39)	critical splice donor site	probably null
R2064:Ptprz1	UTSW	6	23,050,388 (GRCm39)	splice site	probably benign
R2067:Ptprz1	UTSW	6	23,050,388 (GRCm39)	splice site	probably benign
R2108:Ptprz1	UTSW	6	23,033,476 (GRCm39)	missense	probably damaging	0.99
R2152:Ptprz1	UTSW	6	23,030,670 (GRCm39)	missense	probably damaging	0.99
R2166:Ptprz1	UTSW	6	23,045,632 (GRCm39)	missense	possibly damaging	0.90
R2183:Ptprz1	UTSW	6	23,002,284 (GRCm39)	missense	probably benign
R2202:Ptprz1	UTSW	6	23,000,649 (GRCm39)	missense	possibly damaging	0.63
R2238:Ptprz1	UTSW	6	22,987,376 (GRCm39)	missense	probably damaging	1.00
R2290:Ptprz1	UTSW	6	23,000,990 (GRCm39)	missense	probably damaging	1.00
R3027:Ptprz1	UTSW	6	23,016,196 (GRCm39)	missense	possibly damaging	0.89
R3861:Ptprz1	UTSW	6	23,036,894 (GRCm39)	missense	probably damaging	0.98
R4012:Ptprz1	UTSW	6	23,002,584 (GRCm39)	missense	probably damaging	0.99
R4020:Ptprz1	UTSW	6	22,959,623 (GRCm39)	splice site	probably benign
R4158:Ptprz1	UTSW	6	23,022,204 (GRCm39)	missense	possibly damaging	0.73
R4158:Ptprz1	UTSW	6	23,001,683 (GRCm39)	nonsense	probably null
R4159:Ptprz1	UTSW	6	23,001,683 (GRCm39)	nonsense	probably null
R4160:Ptprz1	UTSW	6	23,022,204 (GRCm39)	missense	possibly damaging	0.73
R4606:Ptprz1	UTSW	6	23,001,486 (GRCm39)	missense	possibly damaging	0.80
R4621:Ptprz1	UTSW	6	23,001,453 (GRCm39)	missense	possibly damaging	0.68
R4640:Ptprz1	UTSW	6	22,972,797 (GRCm39)	missense	probably damaging	1.00
R4731:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4732:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4733:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4803:Ptprz1	UTSW	6	23,001,545 (GRCm39)	missense	probably benign	0.00
R4890:Ptprz1	UTSW	6	23,024,957 (GRCm39)	missense	probably damaging	1.00
R5035:Ptprz1	UTSW	6	23,016,214 (GRCm39)	missense	probably benign	0.06
R5052:Ptprz1	UTSW	6	23,045,625 (GRCm39)	missense	probably damaging	1.00
R5106:Ptprz1	UTSW	6	23,000,027 (GRCm39)	missense	probably benign	0.04
R5292:Ptprz1	UTSW	6	23,002,581 (GRCm39)	missense	probably benign	0.31
R5373:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R5374:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R5378:Ptprz1	UTSW	6	23,007,401 (GRCm39)	missense	probably damaging	1.00
R5408:Ptprz1	UTSW	6	23,002,599 (GRCm39)	missense	probably damaging	1.00
R5479:Ptprz1	UTSW	6	23,001,665 (GRCm39)	missense	probably benign
R5524:Ptprz1	UTSW	6	22,986,317 (GRCm39)	splice site	probably null
R5527:Ptprz1	UTSW	6	23,000,052 (GRCm39)	missense	possibly damaging	0.66
R5557:Ptprz1	UTSW	6	23,001,000 (GRCm39)	missense	probably benign	0.04
R5654:Ptprz1	UTSW	6	22,986,133 (GRCm39)	missense	probably damaging	1.00
R5655:Ptprz1	UTSW	6	22,999,772 (GRCm39)	missense	probably benign	0.00
R5658:Ptprz1	UTSW	6	23,016,188 (GRCm39)	missense	probably damaging	1.00
R5663:Ptprz1	UTSW	6	23,035,142 (GRCm39)	missense	probably damaging	1.00
R5765:Ptprz1	UTSW	6	23,000,235 (GRCm39)	missense	probably damaging	1.00
R5822:Ptprz1	UTSW	6	23,001,444 (GRCm39)	missense	probably benign	0.01
R5837:Ptprz1	UTSW	6	23,001,417 (GRCm39)	missense	probably benign	0.00
R6108:Ptprz1	UTSW	6	23,045,658 (GRCm39)	missense	probably damaging	1.00
R6199:Ptprz1	UTSW	6	23,002,470 (GRCm39)	missense	probably benign	0.01
R6245:Ptprz1	UTSW	6	23,051,989 (GRCm39)	missense	probably damaging	1.00
R6257:Ptprz1	UTSW	6	22,959,639 (GRCm39)	missense	probably damaging	1.00
R6488:Ptprz1	UTSW	6	23,001,516 (GRCm39)	nonsense	probably null
R6606:Ptprz1	UTSW	6	23,002,500 (GRCm39)	missense	probably benign	0.27
R6612:Ptprz1	UTSW	6	23,052,081 (GRCm39)	missense	probably damaging	1.00
R6824:Ptprz1	UTSW	6	23,002,130 (GRCm39)	missense	probably benign	0.05
R6834:Ptprz1	UTSW	6	22,999,632 (GRCm39)	missense	probably benign	0.38
R6836:Ptprz1	UTSW	6	23,030,664 (GRCm39)	nonsense	probably null
R6991:Ptprz1	UTSW	6	23,002,686 (GRCm39)	missense	probably benign	0.00
R7044:Ptprz1	UTSW	6	23,044,345 (GRCm39)	missense	probably damaging	1.00
R7048:Ptprz1	UTSW	6	22,961,622 (GRCm39)	missense	probably benign	0.18
R7225:Ptprz1	UTSW	6	23,000,928 (GRCm39)	missense	possibly damaging	0.61
R7284:Ptprz1	UTSW	6	23,000,097 (GRCm39)	missense	probably damaging	1.00
R7360:Ptprz1	UTSW	6	23,000,906 (GRCm39)	missense	probably damaging	1.00
R7501:Ptprz1	UTSW	6	23,001,746 (GRCm39)	nonsense	probably null
R7515:Ptprz1	UTSW	6	23,022,266 (GRCm39)	missense	probably damaging	1.00
R7538:Ptprz1	UTSW	6	22,999,895 (GRCm39)	missense	possibly damaging	0.81
R7567:Ptprz1	UTSW	6	22,959,779 (GRCm39)	missense	probably damaging	0.97
R7599:Ptprz1	UTSW	6	23,002,518 (GRCm39)	missense	not run
R7611:Ptprz1	UTSW	6	23,001,219 (GRCm39)	missense	probably benign
R7685:Ptprz1	UTSW	6	23,024,977 (GRCm39)	missense	probably damaging	1.00
R7707:Ptprz1	UTSW	6	23,002,295 (GRCm39)	missense	probably benign	0.00
R7733:Ptprz1	UTSW	6	23,000,383 (GRCm39)	missense	probably benign	0.31
R7786:Ptprz1	UTSW	6	23,036,992 (GRCm39)	missense	probably damaging	1.00
R7868:Ptprz1	UTSW	6	23,000,963 (GRCm39)	missense	not run
R7882:Ptprz1	UTSW	6	23,002,256 (GRCm39)	missense	probably benign	0.13
R7968:Ptprz1	UTSW	6	22,959,675 (GRCm39)	missense	probably damaging	0.98
R8024:Ptprz1	UTSW	6	23,042,750 (GRCm39)	missense	probably damaging	1.00
R8157:Ptprz1	UTSW	6	23,002,539 (GRCm39)	missense	probably damaging	1.00
R8159:Ptprz1	UTSW	6	23,001,662 (GRCm39)	missense	probably benign
R8354:Ptprz1	UTSW	6	22,999,614 (GRCm39)	missense	probably damaging	0.99
R8496:Ptprz1	UTSW	6	22,972,797 (GRCm39)	missense	probably damaging	0.96
R8757:Ptprz1	UTSW	6	22,972,716 (GRCm39)	missense	possibly damaging	0.74
R8767:Ptprz1	UTSW	6	22,986,187 (GRCm39)	missense	probably damaging	1.00
R8783:Ptprz1	UTSW	6	23,002,026 (GRCm39)	missense	probably benign	0.00
R8811:Ptprz1	UTSW	6	23,030,661 (GRCm39)	missense	probably benign	0.03
R8817:Ptprz1	UTSW	6	23,007,371 (GRCm39)	missense	probably damaging	1.00
R8822:Ptprz1	UTSW	6	23,002,588 (GRCm39)	missense	probably damaging	0.98
R8874:Ptprz1	UTSW	6	23,042,747 (GRCm39)	missense
R9009:Ptprz1	UTSW	6	23,001,653 (GRCm39)	missense	possibly damaging	0.94
R9126:Ptprz1	UTSW	6	23,002,334 (GRCm39)	nonsense	probably null
R9201:Ptprz1	UTSW	6	22,972,869 (GRCm39)	critical splice donor site	probably null
R9210:Ptprz1	UTSW	6	23,050,493 (GRCm39)	missense	probably damaging	0.99
R9212:Ptprz1	UTSW	6	23,050,493 (GRCm39)	missense	probably damaging	0.99
R9229:Ptprz1	UTSW	6	22,986,283 (GRCm39)	missense	probably null	0.03
R9279:Ptprz1	UTSW	6	23,002,444 (GRCm39)	missense	probably benign
R9336:Ptprz1	UTSW	6	23,000,855 (GRCm39)	missense	probably benign	0.01
R9372:Ptprz1	UTSW	6	23,045,706 (GRCm39)	missense	probably damaging	1.00
R9577:Ptprz1	UTSW	6	23,002,202 (GRCm39)	missense	probably damaging	1.00
R9594:Ptprz1	UTSW	6	23,025,026 (GRCm39)	missense	probably damaging	0.98
R9632:Ptprz1	UTSW	6	23,007,292 (GRCm39)	missense	probably damaging	1.00
R9636:Ptprz1	UTSW	6	22,999,994 (GRCm39)	missense	probably benign
R9657:Ptprz1	UTSW	6	23,042,377 (GRCm39)	missense	possibly damaging	0.92
R9694:Ptprz1	UTSW	6	22,959,694 (GRCm39)	missense	probably damaging	1.00
R9716:Ptprz1	UTSW	6	22,959,650 (GRCm39)	missense	probably damaging	1.00
R9794:Ptprz1	UTSW	6	23,000,204 (GRCm39)	missense	probably benign	0.00
Z1176:Ptprz1	UTSW	6	23,051,994 (GRCm39)	missense	probably damaging	0.99
Z1177:Ptprz1	UTSW	6	23,052,023 (GRCm39)	missense	probably damaging	1.00
Z1177:Ptprz1	UTSW	6	22,999,839 (GRCm39)	missense	possibly damaging	0.51

Predicted Primers

PCR Primer
(F):5'- TAAGGTGCACTCCACTCCAC -3'
(R):5'- TGTTGGGAGAAACCATTGTCAAGG -3'

Sequencing Primer
(F):5'- GCTTAACAGTTCCTCACTCGAGTAAG -3'
(R):5'- GAAATGGGCCCACTTCCTAATGG -3'

Posted On

2016-07-06