Incidental Mutation 'R0454:Fbxw10'
| ID |
39902 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fbxw10
|
| Ensembl Gene |
ENSMUSG00000090173 |
| Gene Name |
F-box and WD-40 domain protein 10 |
| Synonyms |
SM2SH2, SM25H2, Fbw10 |
| MMRRC Submission |
038654-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.066)
|
| Stock # |
R0454 (G1)
|
| Quality Score |
174 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
62737895-62768291 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 62767564 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 800
(N800S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135870
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014321]
[ENSMUST00000036085]
[ENSMUST00000150989]
[ENSMUST00000176577]
[ENSMUST00000177336]
|
| AlphaFold |
Q5SUS0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000014321
|
| SMART Domains |
Protein: ENSMUSP00000014321
Gene: ENSMUSG00000014177
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF846
|
32 |
174 |
9.5e-58 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036085
AA Change: N805S
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000046156
Gene: ENSMUSG00000090173
AA Change: N805S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
6e-14 |
BLAST |
|
Blast:WD40
|
416 |
453 |
2e-8 |
BLAST |
|
WD40
|
457 |
496 |
1.78e-5 |
SMART |
|
WD40
|
499 |
536 |
5.55e-7 |
SMART |
|
WD40
|
539 |
575 |
2.84e-4 |
SMART |
|
WD40
|
578 |
615 |
3.81e-5 |
SMART |
|
WD40
|
620 |
656 |
6.9e-1 |
SMART |
|
low complexity region
|
709 |
724 |
N/A |
INTRINSIC |
|
coiled coil region
|
964 |
992 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127646
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128698
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150989
AA Change: N795S
PolyPhen 2
Score 0.083 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000117872
Gene: ENSMUSG00000090173
AA Change: N795S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
1e-13 |
BLAST |
|
Blast:WD40
|
406 |
443 |
2e-8 |
BLAST |
|
WD40
|
447 |
486 |
1.78e-5 |
SMART |
|
WD40
|
489 |
526 |
5.55e-7 |
SMART |
|
WD40
|
529 |
565 |
2.84e-4 |
SMART |
|
WD40
|
568 |
605 |
3.81e-5 |
SMART |
|
WD40
|
610 |
646 |
6.9e-1 |
SMART |
|
low complexity region
|
699 |
714 |
N/A |
INTRINSIC |
|
coiled coil region
|
954 |
982 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154176
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000176577
AA Change: N800S
PolyPhen 2
Score 0.528 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000135870
Gene: ENSMUSG00000090173
AA Change: N800S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
6e-14 |
BLAST |
|
Blast:WD40
|
406 |
443 |
2e-8 |
BLAST |
|
WD40
|
447 |
486 |
1.78e-5 |
SMART |
|
WD40
|
489 |
526 |
5.55e-7 |
SMART |
|
WD40
|
529 |
565 |
2.84e-4 |
SMART |
|
WD40
|
568 |
605 |
3.81e-5 |
SMART |
|
WD40
|
610 |
646 |
6.9e-1 |
SMART |
|
low complexity region
|
704 |
719 |
N/A |
INTRINSIC |
|
coiled coil region
|
959 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177336
|
| SMART Domains |
Protein: ENSMUSP00000135294
Gene: ENSMUSG00000090173
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
5e-14 |
BLAST |
|
Blast:WD40
|
406 |
443 |
1e-8 |
BLAST |
|
WD40
|
447 |
486 |
1.78e-5 |
SMART |
|
WD40
|
489 |
526 |
5.55e-7 |
SMART |
|
WD40
|
529 |
565 |
2.84e-4 |
SMART |
|
WD40
|
568 |
605 |
3.81e-5 |
SMART |
|
WD40
|
610 |
646 |
6.9e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930447F04Rik |
T |
C |
X: 65,347,274 (GRCm39) |
E91G |
unknown |
Het |
| Acot1 |
A |
G |
12: 84,064,113 (GRCm39) |
Q407R |
probably benign |
Het |
| Adcy10 |
T |
A |
1: 165,398,297 (GRCm39) |
Y1465N |
probably damaging |
Het |
| Ahsa2 |
T |
A |
11: 23,440,702 (GRCm39) |
I249F |
probably damaging |
Het |
| Arhgap10 |
T |
C |
8: 77,977,594 (GRCm39) |
N721S |
probably damaging |
Het |
| Arrdc4 |
T |
G |
7: 68,391,619 (GRCm39) |
E216A |
probably damaging |
Het |
| Axin1 |
T |
C |
17: 26,392,637 (GRCm39) |
V306A |
probably benign |
Het |
| Cct3 |
T |
C |
3: 88,210,173 (GRCm39) |
|
probably null |
Het |
| Cfap58 |
G |
A |
19: 47,963,119 (GRCm39) |
|
probably null |
Het |
| Chd9 |
T |
C |
8: 91,699,859 (GRCm39) |
S49P |
possibly damaging |
Het |
| Clcn2 |
C |
A |
16: 20,529,178 (GRCm39) |
|
probably null |
Het |
| Col26a1 |
T |
C |
5: 136,783,047 (GRCm39) |
N286D |
probably benign |
Het |
| Cpt1b |
T |
A |
15: 89,308,596 (GRCm39) |
I111F |
possibly damaging |
Het |
| Cyp4f16 |
T |
A |
17: 32,756,061 (GRCm39) |
I30N |
probably damaging |
Het |
| Ddc |
T |
G |
11: 11,830,587 (GRCm39) |
D19A |
possibly damaging |
Het |
| Depdc1a |
T |
A |
3: 159,222,537 (GRCm39) |
|
probably null |
Het |
| Evc2 |
T |
A |
5: 37,574,828 (GRCm39) |
C1028S |
possibly damaging |
Het |
| Fam228a |
T |
C |
12: 4,781,457 (GRCm39) |
E134G |
probably damaging |
Het |
| Fasl |
T |
C |
1: 161,615,523 (GRCm39) |
E111G |
probably benign |
Het |
| Fras1 |
T |
C |
5: 96,910,524 (GRCm39) |
S3318P |
probably damaging |
Het |
| G3bp1 |
T |
C |
11: 55,389,452 (GRCm39) |
F383L |
probably damaging |
Het |
| Gad1 |
T |
A |
2: 70,409,545 (GRCm39) |
M212K |
probably damaging |
Het |
| Gm17455 |
T |
G |
10: 60,238,752 (GRCm39) |
S6A |
probably benign |
Het |
| Grm5 |
T |
C |
7: 87,779,997 (GRCm39) |
S1146P |
probably damaging |
Het |
| Gsn |
T |
C |
2: 35,194,651 (GRCm39) |
L649P |
probably damaging |
Het |
| H2-DMb1 |
A |
G |
17: 34,374,685 (GRCm39) |
T112A |
probably benign |
Het |
| Hcn3 |
T |
A |
3: 89,060,201 (GRCm39) |
I148F |
probably damaging |
Het |
| Hdac10 |
T |
C |
15: 89,009,961 (GRCm39) |
|
probably null |
Het |
| Hk3 |
C |
A |
13: 55,156,518 (GRCm39) |
D619Y |
probably damaging |
Het |
| Ifi44 |
T |
A |
3: 151,451,134 (GRCm39) |
R272S |
possibly damaging |
Het |
| Il1rap |
A |
C |
16: 26,517,625 (GRCm39) |
D275A |
probably damaging |
Het |
| Irag2 |
A |
G |
6: 145,113,710 (GRCm39) |
R293G |
possibly damaging |
Het |
| Itgam |
A |
T |
7: 127,707,152 (GRCm39) |
N660I |
probably benign |
Het |
| Itpr3 |
T |
C |
17: 27,332,793 (GRCm39) |
M1853T |
probably benign |
Het |
| Lrrc8c |
A |
C |
5: 105,754,965 (GRCm39) |
K247Q |
probably damaging |
Het |
| Map3k21 |
T |
C |
8: 126,668,858 (GRCm39) |
S815P |
probably benign |
Het |
| Mast4 |
A |
G |
13: 102,888,068 (GRCm39) |
S1114P |
probably damaging |
Het |
| Myh8 |
C |
T |
11: 67,194,591 (GRCm39) |
Q1601* |
probably null |
Het |
| Nhlrc2 |
A |
G |
19: 56,558,959 (GRCm39) |
D148G |
probably damaging |
Het |
| Nos1 |
T |
A |
5: 118,081,385 (GRCm39) |
S1196T |
probably benign |
Het |
| Nsmaf |
C |
T |
4: 6,424,874 (GRCm39) |
|
probably null |
Het |
| Obscn |
T |
C |
11: 58,890,449 (GRCm39) |
D7361G |
unknown |
Het |
| Or2t35 |
T |
C |
14: 14,407,777 (GRCm38) |
V183A |
probably damaging |
Het |
| Or52ad1 |
C |
A |
7: 102,996,085 (GRCm39) |
A17S |
probably benign |
Het |
| Or5bw2 |
C |
T |
7: 6,573,359 (GRCm39) |
A123V |
probably damaging |
Het |
| Pank3 |
T |
G |
11: 35,668,536 (GRCm39) |
M175R |
probably benign |
Het |
| Papolg |
A |
G |
11: 23,829,868 (GRCm39) |
|
probably null |
Het |
| Pcdhb21 |
G |
A |
18: 37,647,566 (GRCm39) |
D232N |
probably damaging |
Het |
| Pcdhb22 |
T |
C |
18: 37,651,925 (GRCm39) |
F131S |
probably damaging |
Het |
| Pik3r6 |
G |
A |
11: 68,419,608 (GRCm39) |
A140T |
possibly damaging |
Het |
| Pinlyp |
T |
C |
7: 24,241,947 (GRCm39) |
T87A |
possibly damaging |
Het |
| Pld1 |
T |
C |
3: 28,178,724 (GRCm39) |
S873P |
probably damaging |
Het |
| Pld5 |
T |
A |
1: 176,102,295 (GRCm39) |
Y49F |
probably benign |
Het |
| Polq |
T |
C |
16: 36,855,252 (GRCm39) |
V449A |
probably damaging |
Het |
| Prkca |
A |
G |
11: 107,869,106 (GRCm39) |
V69A |
probably benign |
Het |
| Ptk6 |
A |
G |
2: 180,844,075 (GRCm39) |
S75P |
possibly damaging |
Het |
| Ptprq |
G |
A |
10: 107,418,391 (GRCm39) |
Q1662* |
probably null |
Het |
| Ptprt |
C |
A |
2: 161,395,742 (GRCm39) |
A1144S |
probably damaging |
Het |
| Rrm1 |
T |
A |
7: 102,116,133 (GRCm39) |
W684R |
probably damaging |
Het |
| Ryr1 |
T |
A |
7: 28,735,500 (GRCm39) |
M4093L |
probably damaging |
Het |
| Scnn1a |
C |
T |
6: 125,299,189 (GRCm39) |
L90F |
probably damaging |
Het |
| Slc25a19 |
G |
T |
11: 115,508,423 (GRCm39) |
Y188* |
probably null |
Het |
| Slc31a1 |
C |
T |
4: 62,303,866 (GRCm39) |
|
probably benign |
Het |
| Slc5a11 |
C |
G |
7: 122,864,458 (GRCm39) |
S351R |
possibly damaging |
Het |
| Slc6a17 |
A |
G |
3: 107,384,183 (GRCm39) |
L387P |
probably benign |
Het |
| Slitrk6 |
A |
T |
14: 110,987,364 (GRCm39) |
L781H |
probably damaging |
Het |
| Spam1 |
T |
A |
6: 24,797,837 (GRCm39) |
L331Q |
probably damaging |
Het |
| Spata32 |
A |
G |
11: 103,100,125 (GRCm39) |
W127R |
probably damaging |
Het |
| Spring1 |
A |
G |
5: 118,393,886 (GRCm39) |
E88G |
possibly damaging |
Het |
| Spta1 |
T |
G |
1: 174,041,508 (GRCm39) |
I1324S |
probably damaging |
Het |
| St6galnac4 |
A |
G |
2: 32,484,330 (GRCm39) |
Y176C |
probably damaging |
Het |
| Stk10 |
A |
G |
11: 32,546,724 (GRCm39) |
E327G |
probably damaging |
Het |
| Stxbp5l |
T |
A |
16: 36,954,646 (GRCm39) |
Y912F |
possibly damaging |
Het |
| Tchp |
G |
A |
5: 114,858,243 (GRCm39) |
E459K |
probably benign |
Het |
| Terf2 |
C |
T |
8: 107,822,842 (GRCm39) |
W100* |
probably null |
Het |
| Thoc2l |
T |
G |
5: 104,666,077 (GRCm39) |
S200A |
probably benign |
Het |
| Thrsp |
T |
C |
7: 97,066,634 (GRCm39) |
N26S |
probably damaging |
Het |
| Tln1 |
C |
A |
4: 43,553,504 (GRCm39) |
R297L |
probably benign |
Het |
| Tmeff2 |
C |
A |
1: 50,967,234 (GRCm39) |
T43N |
possibly damaging |
Het |
| Tmx1 |
C |
T |
12: 70,499,947 (GRCm39) |
A2V |
possibly damaging |
Het |
| Tnks1bp1 |
T |
A |
2: 84,902,481 (GRCm39) |
L1053Q |
probably damaging |
Het |
| Trmt10b |
A |
T |
4: 45,304,286 (GRCm39) |
K107N |
probably damaging |
Het |
| Trpa1 |
A |
T |
1: 14,955,972 (GRCm39) |
|
probably null |
Het |
| Trrap |
A |
G |
5: 144,783,287 (GRCm39) |
K3371R |
probably damaging |
Het |
| Tuba3b |
G |
A |
6: 145,563,995 (GRCm39) |
V14I |
probably benign |
Het |
| Usp19 |
T |
C |
9: 108,371,439 (GRCm39) |
|
probably null |
Het |
| Usp28 |
C |
A |
9: 48,950,401 (GRCm39) |
D615E |
possibly damaging |
Het |
| Utp20 |
T |
C |
10: 88,657,931 (GRCm39) |
D43G |
probably benign |
Het |
| Vmn1r58 |
T |
G |
7: 5,413,997 (GRCm39) |
K78Q |
possibly damaging |
Het |
| Vmn2r10 |
T |
C |
5: 109,151,327 (GRCm39) |
M96V |
probably benign |
Het |
| Wdr90 |
T |
C |
17: 26,079,023 (GRCm39) |
E273G |
probably damaging |
Het |
| Xpc |
C |
T |
6: 91,468,208 (GRCm39) |
A860T |
probably benign |
Het |
| Zscan21 |
T |
C |
5: 138,131,865 (GRCm39) |
I463T |
possibly damaging |
Het |
|
| Other mutations in Fbxw10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00941:Fbxw10
|
APN |
11 |
62,764,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01552:Fbxw10
|
APN |
11 |
62,748,510 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01625:Fbxw10
|
APN |
11 |
62,750,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01960:Fbxw10
|
APN |
11 |
62,767,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02457:Fbxw10
|
APN |
11 |
62,765,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02475:Fbxw10
|
APN |
11 |
62,748,561 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02864:Fbxw10
|
APN |
11 |
62,764,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Fbxw10
|
UTSW |
11 |
62,767,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0108:Fbxw10
|
UTSW |
11 |
62,767,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0147:Fbxw10
|
UTSW |
11 |
62,738,307 (GRCm39) |
splice site |
probably null |
|
|
R0180:Fbxw10
|
UTSW |
11 |
62,743,922 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0196:Fbxw10
|
UTSW |
11 |
62,768,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0529:Fbxw10
|
UTSW |
11 |
62,750,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0791:Fbxw10
|
UTSW |
11 |
62,738,282 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0927:Fbxw10
|
UTSW |
11 |
62,767,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1026:Fbxw10
|
UTSW |
11 |
62,765,997 (GRCm39) |
missense |
probably benign |
|
|
R1448:Fbxw10
|
UTSW |
11 |
62,738,418 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1468:Fbxw10
|
UTSW |
11 |
62,753,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Fbxw10
|
UTSW |
11 |
62,753,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1689:Fbxw10
|
UTSW |
11 |
62,750,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1785:Fbxw10
|
UTSW |
11 |
62,750,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2130:Fbxw10
|
UTSW |
11 |
62,750,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2132:Fbxw10
|
UTSW |
11 |
62,750,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2211:Fbxw10
|
UTSW |
11 |
62,758,361 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3078:Fbxw10
|
UTSW |
11 |
62,758,339 (GRCm39) |
splice site |
probably benign |
|
|
R3700:Fbxw10
|
UTSW |
11 |
62,759,983 (GRCm39) |
splice site |
probably null |
|
|
R3932:Fbxw10
|
UTSW |
11 |
62,759,983 (GRCm39) |
splice site |
probably benign |
|
|
R4843:Fbxw10
|
UTSW |
11 |
62,738,151 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4869:Fbxw10
|
UTSW |
11 |
62,753,557 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4879:Fbxw10
|
UTSW |
11 |
62,738,573 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4980:Fbxw10
|
UTSW |
11 |
62,738,583 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5417:Fbxw10
|
UTSW |
11 |
62,767,990 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5531:Fbxw10
|
UTSW |
11 |
62,753,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Fbxw10
|
UTSW |
11 |
62,748,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Fbxw10
|
UTSW |
11 |
62,764,345 (GRCm39) |
nonsense |
probably null |
|
|
R6616:Fbxw10
|
UTSW |
11 |
62,743,850 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6870:Fbxw10
|
UTSW |
11 |
62,746,193 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6967:Fbxw10
|
UTSW |
11 |
62,738,429 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7409:Fbxw10
|
UTSW |
11 |
62,767,606 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7464:Fbxw10
|
UTSW |
11 |
62,744,124 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7542:Fbxw10
|
UTSW |
11 |
62,741,422 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7568:Fbxw10
|
UTSW |
11 |
62,765,994 (GRCm39) |
missense |
probably benign |
|
|
R7733:Fbxw10
|
UTSW |
11 |
62,764,223 (GRCm39) |
missense |
unknown |
|
|
R7793:Fbxw10
|
UTSW |
11 |
62,738,213 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7943:Fbxw10
|
UTSW |
11 |
62,741,487 (GRCm39) |
nonsense |
probably null |
|
|
R8003:Fbxw10
|
UTSW |
11 |
62,748,587 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8323:Fbxw10
|
UTSW |
11 |
62,767,506 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8899:Fbxw10
|
UTSW |
11 |
62,748,567 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8904:Fbxw10
|
UTSW |
11 |
62,765,831 (GRCm39) |
nonsense |
probably null |
|
|
R9035:Fbxw10
|
UTSW |
11 |
62,758,449 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9121:Fbxw10
|
UTSW |
11 |
62,738,153 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9300:Fbxw10
|
UTSW |
11 |
62,768,109 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9332:Fbxw10
|
UTSW |
11 |
62,748,585 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9334:Fbxw10
|
UTSW |
11 |
62,765,910 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9417:Fbxw10
|
UTSW |
11 |
62,753,522 (GRCm39) |
nonsense |
probably null |
|
|
R9476:Fbxw10
|
UTSW |
11 |
62,743,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9510:Fbxw10
|
UTSW |
11 |
62,743,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9520:Fbxw10
|
UTSW |
11 |
62,750,842 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9526:Fbxw10
|
UTSW |
11 |
62,765,945 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9547:Fbxw10
|
UTSW |
11 |
62,767,647 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9602:Fbxw10
|
UTSW |
11 |
62,750,782 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
Z1186:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1186:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCCCTTTTCAGCAACAAGACCTCAG -3'
(R):5'- AGGGGAATGTTGGTTTGTCTCACAC -3'
Sequencing Primer
(F):5'- AGACCTCAGTGTGCCTTTAAGTG -3'
(R):5'- GCTGATCAACTGCGTGTTGA -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation