Mutagenetix > Incidental Mutation

Incidental Mutation 'R5254:Ankhd1'

399423

Institutional Source

Beutler Lab

Gene Symbol

Ankhd1

Ensembl Gene

ENSMUSG00000024483

Gene Name

ankyrin repeat and KH domain containing 1

Synonyms

MMRRC Submission

042825-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5254 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

36559987-36665917 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 36656715 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 907 (I907V)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000006205] [ENSMUST00000142977] [ENSMUST00000155329]

AlphaFold

E9PUR0

Predicted Effect

probably benign
Transcript: ENSMUST00000006205
AA Change: I2418V

PolyPhen 2 Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000006205
Gene: ENSMUSG00000024483
AA Change: I2418V

Domain	Start	End	E-Value	Type
low complexity region	20	38	N/A	INTRINSIC
low complexity region	48	78	N/A	INTRINSIC
low complexity region	91	109	N/A	INTRINSIC
ANK	207	236	2.11e2	SMART
ANK	240	269	3.31e-1	SMART
ANK	274	303	5.24e-4	SMART
ANK	307	336	7.64e-6	SMART
ANK	340	369	2.7e-6	SMART
ANK	374	403	3.23e-4	SMART
ANK	407	436	1.61e-4	SMART
ANK	440	469	5.16e-3	SMART
ANK	473	502	4.16e-7	SMART
ANK	507	536	1.68e-2	SMART
ANK	537	566	7.02e-5	SMART
ANK	570	599	7.95e-4	SMART
ANK	603	632	4.56e-4	SMART
ANK	637	666	9.64e-3	SMART
ANK	670	699	6.71e-2	SMART
coiled coil region	815	855	N/A	INTRINSIC
ANK	1057	1086	2.07e-2	SMART
ANK	1090	1119	2.48e-5	SMART
ANK	1124	1153	3.85e-2	SMART
ANK	1157	1186	1.61e-4	SMART
ANK	1192	1221	1.24e-5	SMART
ANK	1226	1255	1.59e-3	SMART
ANK	1259	1288	3.91e-3	SMART
ANK	1294	1323	5.93e-3	SMART
ANK	1327	1356	9.41e-6	SMART
ANK	1360	1393	3.8e-1	SMART
coiled coil region	1422	1486	N/A	INTRINSIC
low complexity region	1509	1526	N/A	INTRINSIC
low complexity region	1538	1557	N/A	INTRINSIC
low complexity region	1585	1604	N/A	INTRINSIC
KH	1693	1763	5.04e-13	SMART
low complexity region	1968	2001	N/A	INTRINSIC
low complexity region	2041	2057	N/A	INTRINSIC
low complexity region	2064	2081	N/A	INTRINSIC
low complexity region	2334	2346	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000037072
AA Change: I907V

PolyPhen 2 Score 0.049 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000040300
Gene: ENSMUSG00000024483
AA Change: I907V

Domain	Start	End	E-Value	Type
low complexity region	1	16	N/A	INTRINSIC
low complexity region	28	47	N/A	INTRINSIC
low complexity region	75	94	N/A	INTRINSIC
KH	183	253	5.04e-13	SMART
low complexity region	458	491	N/A	INTRINSIC
low complexity region	531	547	N/A	INTRINSIC
low complexity region	554	571	N/A	INTRINSIC
low complexity region	824	836	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000116653

Predicted Effect

probably benign
Transcript: ENSMUST00000140061
AA Change: I447V

PolyPhen 2 Score 0.020 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000121811
Gene: ENSMUSG00000024483
AA Change: I447V

Domain	Start	End	E-Value	Type
low complexity region	54	70	N/A	INTRINSIC
low complexity region	77	94	N/A	INTRINSIC
low complexity region	355	375	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000142977
AA Change: I2418V

PolyPhen 2 Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000120290
Gene: ENSMUSG00000024483
AA Change: I2418V

Domain	Start	End	E-Value	Type
low complexity region	20	38	N/A	INTRINSIC
low complexity region	48	78	N/A	INTRINSIC
low complexity region	91	109	N/A	INTRINSIC
ANK	207	236	2.11e2	SMART
ANK	240	269	3.31e-1	SMART
ANK	274	303	5.24e-4	SMART
ANK	307	336	7.64e-6	SMART
ANK	340	369	2.7e-6	SMART
ANK	374	403	3.23e-4	SMART
ANK	407	436	1.61e-4	SMART
ANK	440	469	5.16e-3	SMART
ANK	473	502	4.16e-7	SMART
ANK	507	536	1.68e-2	SMART
ANK	537	566	7.02e-5	SMART
ANK	570	599	7.95e-4	SMART
ANK	603	632	4.56e-4	SMART
ANK	637	666	9.64e-3	SMART
ANK	670	699	6.71e-2	SMART
coiled coil region	815	855	N/A	INTRINSIC
ANK	1057	1086	2.07e-2	SMART
ANK	1090	1119	2.48e-5	SMART
ANK	1124	1153	3.85e-2	SMART
ANK	1157	1186	1.61e-4	SMART
ANK	1192	1221	1.24e-5	SMART
ANK	1226	1255	1.59e-3	SMART
ANK	1259	1288	3.91e-3	SMART
ANK	1294	1323	5.93e-3	SMART
ANK	1327	1356	9.41e-6	SMART
ANK	1360	1393	3.8e-1	SMART
coiled coil region	1422	1486	N/A	INTRINSIC
low complexity region	1509	1526	N/A	INTRINSIC
low complexity region	1538	1557	N/A	INTRINSIC
low complexity region	1585	1604	N/A	INTRINSIC
KH	1693	1763	5.04e-13	SMART
low complexity region	1968	2001	N/A	INTRINSIC
low complexity region	2041	2057	N/A	INTRINSIC
low complexity region	2064	2081	N/A	INTRINSIC
low complexity region	2334	2346	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000155329
AA Change: I2435V

PolyPhen 2 Score 0.018 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000123270
Gene: ENSMUSG00000024483
AA Change: I2435V

Domain	Start	End	E-Value	Type
low complexity region	20	38	N/A	INTRINSIC
low complexity region	48	78	N/A	INTRINSIC
low complexity region	91	109	N/A	INTRINSIC
ANK	207	236	2.11e2	SMART
ANK	240	269	3.31e-1	SMART
ANK	274	303	5.24e-4	SMART
ANK	307	336	7.64e-6	SMART
ANK	340	369	2.7e-6	SMART
ANK	374	403	3.23e-4	SMART
ANK	407	436	1.61e-4	SMART
ANK	440	469	5.16e-3	SMART
ANK	473	502	4.16e-7	SMART
ANK	507	536	1.68e-2	SMART
ANK	537	566	7.02e-5	SMART
ANK	570	599	7.95e-4	SMART
ANK	603	632	4.56e-4	SMART
ANK	637	666	9.64e-3	SMART
ANK	670	699	6.71e-2	SMART
coiled coil region	815	855	N/A	INTRINSIC
ANK	1057	1086	2.07e-2	SMART
ANK	1090	1119	2.48e-5	SMART
ANK	1124	1153	3.85e-2	SMART
ANK	1157	1186	1.61e-4	SMART
ANK	1192	1221	1.24e-5	SMART
ANK	1226	1255	1.59e-3	SMART
ANK	1259	1288	3.91e-3	SMART
ANK	1294	1323	5.93e-3	SMART
ANK	1327	1356	9.41e-6	SMART
ANK	1360	1393	3.8e-1	SMART
coiled coil region	1422	1486	N/A	INTRINSIC
low complexity region	1509	1526	N/A	INTRINSIC
low complexity region	1538	1557	N/A	INTRINSIC
low complexity region	1585	1604	N/A	INTRINSIC
KH	1693	1763	5.04e-13	SMART
low complexity region	1968	2001	N/A	INTRINSIC
low complexity region	2041	2057	N/A	INTRINSIC
low complexity region	2064	2081	N/A	INTRINSIC
low complexity region	2342	2362	N/A	INTRINSIC

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.0%
20x: 94.6%

Validation Efficiency

98% (82/84)

Allele List at MGI

Other mutations in this stock

Total: 78 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abhd8	G	T	8: 71,458,398 (GRCm38)	C296*	probably null	Het
Adam11	T	A	11: 102,774,272 (GRCm38)	Y413*	probably null	Het
Arrdc5	A	G	17: 56,297,897 (GRCm38)	I130T	probably benign	Het
Asic5	T	A	3: 82,020,987 (GRCm38)	I419K	probably damaging	Het
Atp4a	A	T	7: 30,715,530 (GRCm38)	E248V	probably damaging	Het
Avil	C	A	10: 127,011,761 (GRCm38)	V154L	probably benign	Het
Bclaf1	T	A	10: 20,323,536 (GRCm38)	H226Q	possibly damaging	Het
Cald1	A	G	6: 34,746,416 (GRCm38)		probably benign	Het
Cd200r4	A	C	16: 44,832,090 (GRCm38)	D27A	possibly damaging	Het
Cdsn	T	A	17: 35,552,202 (GRCm38)	M1K	probably null	Het
Cfap46	T	A	7: 139,678,514 (GRCm38)	H281L	possibly damaging	Het
Chaf1a	T	C	17: 56,062,606 (GRCm38)	F533L	probably benign	Het
Chil4	T	A	3: 106,219,452 (GRCm38)	I5F	probably benign	Het
Ctu2	A	T	8: 122,476,588 (GRCm38)	R48W	probably damaging	Het
Daam1	A	T	12: 71,946,576 (GRCm38)	H373L	unknown	Het
Dcaf10	T	A	4: 45,370,415 (GRCm38)	Y328N	possibly damaging	Het
Dst	A	T	1: 34,177,931 (GRCm38)	K1151*	probably null	Het
Ect2	T	C	3: 27,130,070 (GRCm38)	D503G	probably damaging	Het
Epm2a	C	A	10: 11,457,345 (GRCm38)	D307E	probably benign	Het
Exph5	A	T	9: 53,337,930 (GRCm38)	D73V	probably damaging	Het
Fam20b	C	T	1: 156,705,740 (GRCm38)	G102D	probably damaging	Het
Fat2	T	C	11: 55,281,175 (GRCm38)	N2904S	probably damaging	Het
Flt3	T	A	5: 147,375,690 (GRCm38)	Q147L	possibly damaging	Het
Fndc11	A	G	2: 181,222,163 (GRCm38)	T254A	possibly damaging	Het
Galnt15	C	T	14: 32,058,287 (GRCm38)	R514*	probably null	Het
Gbgt1	A	G	2: 28,505,208 (GRCm38)	D286G	probably damaging	Het
Ggt1	T	A	10: 75,579,198 (GRCm38)		probably null	Het
Gm26526	A	T	7: 39,589,234 (GRCm38)		noncoding transcript	Het
H2-K1	T	C	17: 33,997,462 (GRCm38)	T237A	probably damaging	Het
Igf1r	T	A	7: 68,207,319 (GRCm38)	S1010T	probably damaging	Het
Il21	T	C	3: 37,227,735 (GRCm38)	T87A	possibly damaging	Het
Kmt2b	G	A	7: 30,569,175 (GRCm38)	R2010C	probably damaging	Het
Kmt2c	G	A	5: 25,314,594 (GRCm38)	P2173S	probably benign	Het
Krt1	A	T	15: 101,846,368 (GRCm38)	S512T	unknown	Het
Krtap16-1	G	A	11: 99,985,598 (GRCm38)	R327*	probably null	Het
Lama1	T	A	17: 67,756,716 (GRCm38)	I745N	probably benign	Het
Lrrk1	T	A	7: 66,307,107 (GRCm38)	N372I	probably benign	Het
Lyst	A	T	13: 13,683,070 (GRCm38)	E2481D	probably benign	Het
Map2k1	A	T	9: 64,187,745 (GRCm38)		probably benign	Het
Mbip	A	G	12: 56,337,443 (GRCm38)	V215A	probably damaging	Het
Mdc1	T	A	17: 35,847,922 (GRCm38)	V398D	probably benign	Het
Mog	T	G	17: 37,012,372 (GRCm38)	I225L	probably benign	Het
Mrgprx3-ps	T	A	7: 47,309,436 (GRCm38)		noncoding transcript	Het
Muc5b	C	T	7: 141,864,540 (GRCm38)	S3741L	probably benign	Het
Myo5a	A	T	9: 75,130,120 (GRCm38)	I202F	probably damaging	Het
Myo5b	A	T	18: 74,700,606 (GRCm38)	I818F	possibly damaging	Het
Nfia	T	A	4: 98,014,297 (GRCm38)	M262K	probably damaging	Het
Nisch	C	T	14: 31,206,567 (GRCm38)		probably null	Het
Nkd1	A	G	8: 88,589,194 (GRCm38)	D64G	probably damaging	Het
Nt5c2	T	A	19: 46,893,560 (GRCm38)	K284*	probably null	Het
Olfr1052	A	T	2: 86,297,921 (GRCm38)	Y35F	probably damaging	Het
Olfr1058	A	T	2: 86,386,140 (GRCm38)	S93T	possibly damaging	Het
Olfr262	A	G	19: 12,241,248 (GRCm38)	S138P	probably damaging	Het
Olfr305	A	T	7: 86,364,190 (GRCm38)	V49E	possibly damaging	Het
Olfr619	T	G	7: 103,603,789 (GRCm38)	I45R	probably benign	Het
Olfr723	A	T	14: 49,928,779 (GRCm38)	I255N	probably damaging	Het
Olfr725	C	A	14: 50,034,678 (GRCm38)	A242S	possibly damaging	Het
Olfr972	A	T	9: 39,873,445 (GRCm38)	T57S	possibly damaging	Het
Pcdhb17	A	T	18: 37,486,825 (GRCm38)	D556V	probably damaging	Het
Pcdhga8	A	T	18: 37,726,620 (GRCm38)	D243V	probably benign	Het
Polq	A	T	16: 37,089,319 (GRCm38)	Q2355L	probably damaging	Het
Slc22a30	G	A	19: 8,344,393 (GRCm38)	Q436*	probably null	Het
Slc5a4a	C	A	10: 76,182,738 (GRCm38)	Y506*	probably null	Het
Sp110	G	C	1: 85,577,202 (GRCm38)		probably benign	Het
Tarbp1	G	A	8: 126,467,156 (GRCm38)	H336Y	probably damaging	Het
Tas2r134	T	G	2: 51,627,547 (GRCm38)	F13V	probably benign	Het
Tgfb2	A	G	1: 186,704,483 (GRCm38)	Y98H	probably damaging	Het
Tmprss11a	C	A	5: 86,411,806 (GRCm38)	V376L	probably damaging	Het
Tmprss11f	T	A	5: 86,538,033 (GRCm38)	K158N	probably benign	Het
Tnip2	G	T	5: 34,503,578 (GRCm38)	Q177K	probably damaging	Het
Trp53inp1	T	A	4: 11,165,075 (GRCm38)		probably null	Het
Ttc28	C	T	5: 111,271,238 (GRCm38)	P1398S	probably benign	Het
Umodl1	T	G	17: 30,980,359 (GRCm38)	I308S	possibly damaging	Het
Vcan	A	T	13: 89,691,600 (GRCm38)	S1942T	probably damaging	Het
Vmn2r124	T	A	17: 18,063,077 (GRCm38)	N344K	probably benign	Het
Vmn2r25	C	G	6: 123,825,318 (GRCm38)	C542S	probably damaging	Het
Wiz	T	A	17: 32,378,496 (GRCm38)		probably benign	Het
Wrap73	A	G	4: 154,155,346 (GRCm38)	Y343C	probably benign	Het

Other mutations in Ankhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Ankhd1	APN	18	36,665,459 (GRCm38)	unclassified	probably benign
IGL00927:Ankhd1	APN	18	36,632,072 (GRCm38)	missense	probably benign	0.01
IGL01367:Ankhd1	APN	18	36,578,643 (GRCm38)	missense	probably benign	0.16
IGL01624:Ankhd1	APN	18	36,658,013 (GRCm38)	missense	probably damaging	1.00
IGL01725:Ankhd1	APN	18	36,648,153 (GRCm38)	missense	probably benign	0.04
IGL01767:Ankhd1	APN	18	36,648,374 (GRCm38)	missense	probably damaging	1.00
IGL02005:Ankhd1	APN	18	36,648,426 (GRCm38)	missense	probably damaging	1.00
IGL02009:Ankhd1	APN	18	36,624,661 (GRCm38)	missense	probably damaging	1.00
IGL02246:Ankhd1	APN	18	36,656,726 (GRCm38)	missense	probably damaging	1.00
IGL02336:Ankhd1	APN	18	36,594,814 (GRCm38)	missense	probably damaging	0.97
IGL02628:Ankhd1	APN	18	36,647,703 (GRCm38)	missense	probably benign	0.00
IGL02644:Ankhd1	APN	18	36,578,775 (GRCm38)	critical splice donor site	probably null
IGL02735:Ankhd1	APN	18	36,648,546 (GRCm38)	missense	probably benign	0.00
IGL02877:Ankhd1	APN	18	36,594,823 (GRCm38)	missense	probably damaging	1.00
IGL03129:Ankhd1	APN	18	36,658,008 (GRCm38)	nonsense	probably null
IGL03163:Ankhd1	APN	18	36,647,628 (GRCm38)	missense	probably damaging	0.97
IGL03182:Ankhd1	APN	18	36,578,774 (GRCm38)	missense	probably benign	0.06
IGL03184:Ankhd1	APN	18	36,647,777 (GRCm38)	missense	probably damaging	1.00
IGL03398:Ankhd1	APN	18	36,656,837 (GRCm38)	splice site	probably benign
FR4304:Ankhd1	UTSW	18	36,560,924 (GRCm38)	small insertion	probably benign
R0051:Ankhd1	UTSW	18	36,647,188 (GRCm38)	unclassified	probably benign
R0089:Ankhd1	UTSW	18	36,640,356 (GRCm38)	missense	probably damaging	0.99
R0105:Ankhd1	UTSW	18	36,646,766 (GRCm38)	missense	probably damaging	1.00
R0149:Ankhd1	UTSW	18	36,647,214 (GRCm38)	missense	probably damaging	1.00
R0243:Ankhd1	UTSW	18	36,634,734 (GRCm38)	missense	probably damaging	1.00
R0322:Ankhd1	UTSW	18	36,658,008 (GRCm38)	nonsense	probably null
R0361:Ankhd1	UTSW	18	36,647,214 (GRCm38)	missense	probably damaging	1.00
R0389:Ankhd1	UTSW	18	36,644,599 (GRCm38)	missense	possibly damaging	0.48
R0418:Ankhd1	UTSW	18	36,634,300 (GRCm38)	missense	probably damaging	1.00
R0443:Ankhd1	UTSW	18	36,644,599 (GRCm38)	missense	possibly damaging	0.48
R0540:Ankhd1	UTSW	18	36,640,280 (GRCm38)	missense	probably damaging	1.00
R0607:Ankhd1	UTSW	18	36,640,280 (GRCm38)	missense	probably damaging	1.00
R0738:Ankhd1	UTSW	18	36,645,249 (GRCm38)	splice site	probably benign
R1127:Ankhd1	UTSW	18	36,634,346 (GRCm38)	missense	probably damaging	1.00
R1434:Ankhd1	UTSW	18	36,625,159 (GRCm38)	missense	probably benign	0.09
R1742:Ankhd1	UTSW	18	36,625,265 (GRCm38)	missense	probably damaging	1.00
R1776:Ankhd1	UTSW	18	36,647,308 (GRCm38)	missense	probably benign	0.17
R1856:Ankhd1	UTSW	18	36,644,527 (GRCm38)	missense	probably benign	0.00
R1923:Ankhd1	UTSW	18	36,648,030 (GRCm38)	missense	probably benign	0.08
R2044:Ankhd1	UTSW	18	36,645,113 (GRCm38)	missense	probably benign	0.31
R2112:Ankhd1	UTSW	18	36,641,626 (GRCm38)	missense	probably damaging	1.00
R2115:Ankhd1	UTSW	18	36,634,308 (GRCm38)	missense	probably damaging	1.00
R2136:Ankhd1	UTSW	18	36,647,621 (GRCm38)	missense	probably benign
R2196:Ankhd1	UTSW	18	36,648,379 (GRCm38)	missense	probably damaging	1.00
R2291:Ankhd1	UTSW	18	36,644,333 (GRCm38)	missense	probably benign	0.31
R2305:Ankhd1	UTSW	18	36,642,926 (GRCm38)	missense	possibly damaging	0.59
R2309:Ankhd1	UTSW	18	36,624,765 (GRCm38)	missense	probably damaging	1.00
R2519:Ankhd1	UTSW	18	36,578,543 (GRCm38)	splice site	probably null
R2958:Ankhd1	UTSW	18	36,634,729 (GRCm38)	missense	probably damaging	1.00
R3978:Ankhd1	UTSW	18	36,647,613 (GRCm38)	missense	probably damaging	0.96
R3980:Ankhd1	UTSW	18	36,647,613 (GRCm38)	missense	probably damaging	0.96
R4159:Ankhd1	UTSW	18	36,589,540 (GRCm38)	missense	possibly damaging	0.91
R4199:Ankhd1	UTSW	18	36,661,048 (GRCm38)	unclassified	probably benign
R4323:Ankhd1	UTSW	18	36,578,633 (GRCm38)	missense	probably damaging	1.00
R4356:Ankhd1	UTSW	18	36,643,043 (GRCm38)	nonsense	probably null
R4496:Ankhd1	UTSW	18	36,560,786 (GRCm38)	missense	probably damaging	0.98
R4551:Ankhd1	UTSW	18	36,655,507 (GRCm38)	splice site	probably null
R4590:Ankhd1	UTSW	18	36,583,644 (GRCm38)	missense	probably damaging	1.00
R4667:Ankhd1	UTSW	18	36,648,021 (GRCm38)	missense	possibly damaging	0.77
R4889:Ankhd1	UTSW	18	36,578,734 (GRCm38)	missense	probably null	0.00
R4923:Ankhd1	UTSW	18	36,589,452 (GRCm38)	missense	probably damaging	1.00
R5091:Ankhd1	UTSW	18	36,625,027 (GRCm38)	missense	possibly damaging	0.68
R5314:Ankhd1	UTSW	18	36,561,058 (GRCm38)	splice site	probably null
R5336:Ankhd1	UTSW	18	36,646,716 (GRCm38)	missense	probably damaging	1.00
R5367:Ankhd1	UTSW	18	36,589,408 (GRCm38)	missense	probably damaging	1.00
R5384:Ankhd1	UTSW	18	36,591,495 (GRCm38)	missense	probably damaging	1.00
R5385:Ankhd1	UTSW	18	36,591,495 (GRCm38)	missense	probably damaging	1.00
R5387:Ankhd1	UTSW	18	36,634,644 (GRCm38)	missense	probably damaging	1.00
R5458:Ankhd1	UTSW	18	36,648,485 (GRCm38)	missense	probably benign	0.01
R5599:Ankhd1	UTSW	18	36,560,807 (GRCm38)	missense	probably damaging	0.98
R5659:Ankhd1	UTSW	18	36,561,050 (GRCm38)	missense	probably damaging	1.00
R5750:Ankhd1	UTSW	18	36,624,902 (GRCm38)	missense	probably benign	0.00
R5874:Ankhd1	UTSW	18	36,640,269 (GRCm38)	missense	possibly damaging	0.92
R5894:Ankhd1	UTSW	18	36,647,524 (GRCm38)	missense	probably damaging	0.99
R5969:Ankhd1	UTSW	18	36,600,834 (GRCm38)	missense	probably damaging	1.00
R6133:Ankhd1	UTSW	18	36,625,126 (GRCm38)	missense	possibly damaging	0.77
R6190:Ankhd1	UTSW	18	36,611,809 (GRCm38)	missense	possibly damaging	0.84
R6247:Ankhd1	UTSW	18	36,654,146 (GRCm38)	missense	probably benign	0.00
R6512:Ankhd1	UTSW	18	36,591,456 (GRCm38)	missense	probably damaging	1.00
R6649:Ankhd1	UTSW	18	36,600,783 (GRCm38)	splice site	probably null
R6653:Ankhd1	UTSW	18	36,600,783 (GRCm38)	splice site	probably null
R6763:Ankhd1	UTSW	18	36,642,969 (GRCm38)	missense	probably benign	0.31
R6976:Ankhd1	UTSW	18	36,648,254 (GRCm38)	missense	probably benign	0.00
R7075:Ankhd1	UTSW	18	36,559,989 (GRCm38)	missense
R7208:Ankhd1	UTSW	18	36,625,028 (GRCm38)	missense	probably benign
R7305:Ankhd1	UTSW	18	36,632,205 (GRCm38)	missense
R7615:Ankhd1	UTSW	18	36,656,773 (GRCm38)	missense
R7654:Ankhd1	UTSW	18	36,594,101 (GRCm38)	missense	probably damaging	1.00
R7781:Ankhd1	UTSW	18	36,625,205 (GRCm38)	missense	probably damaging	1.00
R7842:Ankhd1	UTSW	18	36,647,828 (GRCm38)	missense	probably benign	0.00
R7965:Ankhd1	UTSW	18	36,658,412 (GRCm38)	missense
R8006:Ankhd1	UTSW	18	36,648,719 (GRCm38)	missense
R8037:Ankhd1	UTSW	18	36,638,623 (GRCm38)	missense	probably damaging	0.98
R8123:Ankhd1	UTSW	18	36,575,083 (GRCm38)	missense
R8195:Ankhd1	UTSW	18	36,654,177 (GRCm38)	missense
R8305:Ankhd1	UTSW	18	36,647,166 (GRCm38)	missense	possibly damaging	0.79
R8708:Ankhd1	UTSW	18	36,594,291 (GRCm38)	missense	probably damaging	1.00
R8827:Ankhd1	UTSW	18	36,624,580 (GRCm38)	nonsense	probably null
R9138:Ankhd1	UTSW	18	36,560,908 (GRCm38)	small deletion	probably benign
R9139:Ankhd1	UTSW	18	36,578,757 (GRCm38)	missense
R9186:Ankhd1	UTSW	18	36,634,330 (GRCm38)	missense	possibly damaging	0.95
R9245:Ankhd1	UTSW	18	36,655,600 (GRCm38)	missense
R9254:Ankhd1	UTSW	18	36,644,627 (GRCm38)	missense	probably benign	0.03
R9262:Ankhd1	UTSW	18	36,632,746 (GRCm38)	missense
R9379:Ankhd1	UTSW	18	36,644,627 (GRCm38)	missense	probably benign	0.03
R9436:Ankhd1	UTSW	18	36,641,601 (GRCm38)	missense	probably benign	0.04
R9436:Ankhd1	UTSW	18	36,560,988 (GRCm38)	missense	probably benign	0.39
R9541:Ankhd1	UTSW	18	36,624,644 (GRCm38)	missense
R9584:Ankhd1	UTSW	18	36,665,451 (GRCm38)	missense	probably benign	0.06
R9664:Ankhd1	UTSW	18	36,647,825 (GRCm38)	missense	probably benign	0.03
RF001:Ankhd1	UTSW	18	36,560,921 (GRCm38)	small insertion	probably benign
RF004:Ankhd1	UTSW	18	36,560,910 (GRCm38)	small insertion	probably benign
RF007:Ankhd1	UTSW	18	36,560,909 (GRCm38)	small insertion	probably benign
RF008:Ankhd1	UTSW	18	36,560,924 (GRCm38)	small insertion	probably benign
RF009:Ankhd1	UTSW	18	36,560,922 (GRCm38)	small insertion	probably benign
RF013:Ankhd1	UTSW	18	36,560,926 (GRCm38)	small insertion	probably benign
RF016:Ankhd1	UTSW	18	36,560,910 (GRCm38)	small insertion	probably benign
RF016:Ankhd1	UTSW	18	36,560,909 (GRCm38)	small insertion	probably benign
RF017:Ankhd1	UTSW	18	36,560,909 (GRCm38)	small insertion	probably benign
RF018:Ankhd1	UTSW	18	36,560,912 (GRCm38)	small insertion	probably benign
RF026:Ankhd1	UTSW	18	36,560,912 (GRCm38)	small insertion	probably benign
RF030:Ankhd1	UTSW	18	36,560,927 (GRCm38)	small insertion	probably benign
RF030:Ankhd1	UTSW	18	36,560,913 (GRCm38)	small insertion	probably benign
RF039:Ankhd1	UTSW	18	36,560,918 (GRCm38)	small insertion	probably benign
RF043:Ankhd1	UTSW	18	36,560,917 (GRCm38)	small insertion	probably benign
RF046:Ankhd1	UTSW	18	36,560,926 (GRCm38)	small insertion	probably benign
RF047:Ankhd1	UTSW	18	36,560,923 (GRCm38)	small insertion	probably benign
RF047:Ankhd1	UTSW	18	36,560,917 (GRCm38)	small insertion	probably benign
RF049:Ankhd1	UTSW	18	36,560,923 (GRCm38)	small insertion	probably benign
RF050:Ankhd1	UTSW	18	36,560,927 (GRCm38)	small insertion	probably benign
RF054:Ankhd1	UTSW	18	36,560,929 (GRCm38)	small insertion	probably benign
RF057:Ankhd1	UTSW	18	36,560,929 (GRCm38)	small insertion	probably benign
RF060:Ankhd1	UTSW	18	36,560,922 (GRCm38)	small insertion	probably benign
RF061:Ankhd1	UTSW	18	36,560,921 (GRCm38)	small insertion	probably benign
RF062:Ankhd1	UTSW	18	36,560,918 (GRCm38)	small insertion	probably benign
X0027:Ankhd1	UTSW	18	36,624,832 (GRCm38)	missense	probably damaging	1.00
X0065:Ankhd1	UTSW	18	36,578,764 (GRCm38)	nonsense	probably null
X0066:Ankhd1	UTSW	18	36,646,704 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTGGGAATATACAAGGCTATTCACC -3'
(R):5'- GTGTCTGGCAGTGTATCAAAGTTAC -3'

Sequencing Primer
(F):5'- GGCTATTCACCTATTTTTCTAGGAAC -3'
(R):5'- CAATGACACATGTTGACTCACTG -3'

Posted On

2016-07-06