Incidental Mutation 'R5256:Nebl'
| ID |
399569 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nebl
|
| Ensembl Gene |
ENSMUSG00000053702 |
| Gene Name |
nebulette |
| Synonyms |
Lnebl, D830029A09Rik, A630080F05Rik, 1200007O21Rik |
| MMRRC Submission |
042827-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5256 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
17348720-17736275 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 17438786 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 209
(S209P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028080]
[ENSMUST00000124270]
[ENSMUST00000131957]
[ENSMUST00000132418]
[ENSMUST00000145492]
|
| AlphaFold |
Q0II04 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028080
|
| SMART Domains |
Protein: ENSMUSP00000028080
Gene: ENSMUSG00000053702
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
4 |
56 |
6.95e-14 |
SMART |
|
NEBU
|
62 |
92 |
3.35e-8 |
SMART |
|
NEBU
|
98 |
128 |
4.88e-10 |
SMART |
|
NEBU
|
134 |
164 |
3.82e-3 |
SMART |
|
SH3
|
213 |
270 |
2.12e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124270
AA Change: S209P
PolyPhen 2
Score 0.366 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000117805
Gene: ENSMUSG00000053702
AA Change: S209P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
25 |
N/A |
INTRINSIC |
|
NEBU
|
30 |
60 |
1.21e-5 |
SMART |
|
NEBU
|
65 |
95 |
5.4e-3 |
SMART |
|
NEBU
|
102 |
132 |
4.46e-4 |
SMART |
|
NEBU
|
139 |
169 |
1.31e-1 |
SMART |
|
NEBU
|
173 |
203 |
5.4e-3 |
SMART |
|
NEBU
|
207 |
237 |
2.74e-4 |
SMART |
|
NEBU
|
245 |
275 |
1.57e0 |
SMART |
|
NEBU
|
280 |
310 |
9.67e-1 |
SMART |
|
NEBU
|
315 |
345 |
6.25e-8 |
SMART |
|
NEBU
|
351 |
381 |
5.97e-5 |
SMART |
|
NEBU
|
387 |
418 |
2.56e-4 |
SMART |
|
NEBU
|
425 |
455 |
8.91e-4 |
SMART |
|
NEBU
|
462 |
492 |
4.92e-6 |
SMART |
|
NEBU
|
499 |
529 |
2.33e-7 |
SMART |
|
NEBU
|
536 |
566 |
1.84e-5 |
SMART |
|
NEBU
|
571 |
601 |
2.23e-4 |
SMART |
|
NEBU
|
602 |
632 |
1.24e-2 |
SMART |
|
NEBU
|
664 |
694 |
6.6e-7 |
SMART |
|
NEBU
|
695 |
725 |
6.86e-5 |
SMART |
|
NEBU
|
726 |
756 |
2.03e-7 |
SMART |
|
NEBU
|
761 |
791 |
1.74e-6 |
SMART |
|
NEBU
|
797 |
827 |
3.82e-3 |
SMART |
|
SH3
|
957 |
1014 |
2.12e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124611
|
| SMART Domains |
Protein: ENSMUSP00000116065
Gene: ENSMUSG00000053702
| Domain | Start | End | E-Value | Type |
|---|
|
NEBU
|
3 |
33 |
4.88e-10 |
SMART |
|
NEBU
|
39 |
69 |
3.82e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131957
AA Change: S209P
PolyPhen 2
Score 0.366 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000118525
Gene: ENSMUSG00000053702
AA Change: S209P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
25 |
N/A |
INTRINSIC |
|
NEBU
|
30 |
60 |
1.21e-5 |
SMART |
|
NEBU
|
65 |
95 |
5.4e-3 |
SMART |
|
NEBU
|
102 |
132 |
4.46e-4 |
SMART |
|
NEBU
|
139 |
169 |
1.31e-1 |
SMART |
|
NEBU
|
173 |
203 |
5.4e-3 |
SMART |
|
NEBU
|
207 |
237 |
2.74e-4 |
SMART |
|
NEBU
|
245 |
275 |
7.35e0 |
SMART |
|
NEBU
|
280 |
310 |
6.25e-8 |
SMART |
|
NEBU
|
316 |
346 |
5.97e-5 |
SMART |
|
NEBU
|
352 |
383 |
2.56e-4 |
SMART |
|
NEBU
|
390 |
420 |
8.91e-4 |
SMART |
|
NEBU
|
427 |
457 |
4.92e-6 |
SMART |
|
NEBU
|
464 |
494 |
2.33e-7 |
SMART |
|
NEBU
|
501 |
525 |
1.02e2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132418
AA Change: S209P
PolyPhen 2
Score 0.207 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000122024
Gene: ENSMUSG00000053702
AA Change: S209P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
25 |
N/A |
INTRINSIC |
|
NEBU
|
30 |
60 |
1.21e-5 |
SMART |
|
NEBU
|
65 |
95 |
5.4e-3 |
SMART |
|
NEBU
|
102 |
132 |
4.46e-4 |
SMART |
|
NEBU
|
139 |
169 |
1.31e-1 |
SMART |
|
NEBU
|
173 |
203 |
5.4e-3 |
SMART |
|
NEBU
|
207 |
237 |
2.74e-4 |
SMART |
|
NEBU
|
245 |
275 |
7.35e0 |
SMART |
|
NEBU
|
280 |
310 |
6.25e-8 |
SMART |
|
NEBU
|
316 |
346 |
5.97e-5 |
SMART |
|
NEBU
|
352 |
383 |
2.56e-4 |
SMART |
|
NEBU
|
390 |
420 |
4.78e-4 |
SMART |
|
NEBU
|
427 |
450 |
6.81e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145492
AA Change: S209P
PolyPhen 2
Score 0.157 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000121313
Gene: ENSMUSG00000053702
AA Change: S209P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
25 |
N/A |
INTRINSIC |
|
NEBU
|
30 |
60 |
1.21e-5 |
SMART |
|
NEBU
|
65 |
95 |
5.4e-3 |
SMART |
|
NEBU
|
102 |
132 |
4.46e-4 |
SMART |
|
NEBU
|
139 |
169 |
1.31e-1 |
SMART |
|
NEBU
|
173 |
203 |
5.4e-3 |
SMART |
|
NEBU
|
207 |
237 |
2.74e-4 |
SMART |
|
NEBU
|
245 |
275 |
7.35e0 |
SMART |
|
NEBU
|
280 |
310 |
6.25e-8 |
SMART |
|
NEBU
|
316 |
346 |
5.97e-5 |
SMART |
|
NEBU
|
352 |
383 |
2.56e-4 |
SMART |
|
NEBU
|
390 |
420 |
8.91e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145545
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.8%
|
| Validation Efficiency |
97% (95/98) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730015C16Rik |
C |
A |
4: 108,705,262 (GRCm39) |
|
probably benign |
Het |
| Actr1b |
T |
C |
1: 36,739,173 (GRCm39) |
H372R |
probably benign |
Het |
| Ampd2 |
C |
A |
3: 107,986,865 (GRCm39) |
|
probably benign |
Het |
| Anapc4 |
A |
G |
5: 53,020,936 (GRCm39) |
S612G |
probably benign |
Het |
| Arhgef7 |
T |
C |
8: 11,850,811 (GRCm39) |
L141P |
probably damaging |
Het |
| Atl1 |
A |
G |
12: 70,006,107 (GRCm39) |
D471G |
probably damaging |
Het |
| Atrn |
A |
G |
2: 130,787,939 (GRCm39) |
D247G |
probably benign |
Het |
| Bag1 |
T |
A |
4: 40,948,022 (GRCm39) |
R61W |
probably damaging |
Het |
| Card10 |
C |
T |
15: 78,662,451 (GRCm39) |
R898H |
probably damaging |
Het |
| Cct6b |
G |
A |
11: 82,655,046 (GRCm39) |
A3V |
probably damaging |
Het |
| Cfap54 |
A |
T |
10: 92,770,953 (GRCm39) |
L2097* |
probably null |
Het |
| Cfap54 |
T |
C |
10: 92,880,885 (GRCm39) |
|
probably null |
Het |
| Chd5 |
T |
C |
4: 152,456,554 (GRCm39) |
F964L |
probably benign |
Het |
| Cog5 |
A |
G |
12: 31,936,204 (GRCm39) |
T584A |
probably benign |
Het |
| Cpa2 |
T |
A |
6: 30,547,196 (GRCm39) |
N157K |
probably damaging |
Het |
| Cpeb1 |
A |
T |
7: 81,001,587 (GRCm39) |
M440K |
probably damaging |
Het |
| Cracr2a |
G |
A |
6: 127,580,992 (GRCm39) |
C56Y |
probably damaging |
Het |
| Ddb2 |
A |
C |
2: 91,067,073 (GRCm39) |
L30R |
probably damaging |
Het |
| Dlk1 |
T |
A |
12: 109,425,697 (GRCm39) |
I190N |
probably damaging |
Het |
| Dnaaf4 |
T |
C |
9: 72,879,362 (GRCm39) |
|
probably null |
Het |
| Dnajc13 |
T |
A |
9: 104,080,528 (GRCm39) |
Y851F |
possibly damaging |
Het |
| Dop1a |
T |
A |
9: 86,397,381 (GRCm39) |
L895Q |
probably damaging |
Het |
| F7 |
G |
A |
8: 13,080,763 (GRCm39) |
C122Y |
probably damaging |
Het |
| Frrs1 |
T |
C |
3: 116,696,749 (GRCm39) |
V573A |
possibly damaging |
Het |
| Galnt2l |
T |
C |
8: 122,997,175 (GRCm39) |
|
probably benign |
Het |
| Gm17541 |
A |
T |
12: 4,739,672 (GRCm39) |
|
probably benign |
Het |
| Gm5519 |
A |
T |
19: 33,800,576 (GRCm39) |
H90L |
probably damaging |
Het |
| Gm5526 |
T |
A |
1: 45,896,569 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5709 |
A |
T |
3: 59,509,971 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
T |
A |
9: 118,385,569 (GRCm39) |
V869D |
possibly damaging |
Het |
| Grm7 |
A |
T |
6: 111,335,182 (GRCm39) |
Q531L |
probably benign |
Het |
| Hnrnpu |
C |
A |
1: 178,163,458 (GRCm39) |
C265F |
unknown |
Het |
| Hoxd3 |
G |
A |
2: 74,577,211 (GRCm39) |
V364I |
possibly damaging |
Het |
| Hspb8 |
T |
C |
5: 116,547,532 (GRCm39) |
D150G |
probably damaging |
Het |
| Hydin |
C |
A |
8: 111,313,855 (GRCm39) |
N4244K |
possibly damaging |
Het |
| Ik |
A |
G |
18: 36,881,926 (GRCm39) |
D136G |
probably benign |
Het |
| Il11ra1 |
T |
C |
4: 41,767,932 (GRCm39) |
|
probably benign |
Het |
| Jph1 |
T |
C |
1: 17,161,622 (GRCm39) |
I347V |
probably benign |
Het |
| Klk1 |
T |
A |
7: 43,870,985 (GRCm39) |
|
probably benign |
Het |
| Lmcd1 |
T |
A |
6: 112,265,087 (GRCm39) |
|
probably benign |
Het |
| Lnx1 |
C |
T |
5: 74,846,315 (GRCm39) |
C45Y |
probably damaging |
Het |
| Macc1 |
T |
A |
12: 119,410,264 (GRCm39) |
M344K |
possibly damaging |
Het |
| Madcam1 |
A |
G |
10: 79,500,779 (GRCm39) |
E32G |
possibly damaging |
Het |
| Mat2a |
T |
C |
6: 72,411,316 (GRCm39) |
D383G |
probably benign |
Het |
| Mpst |
T |
A |
15: 78,297,849 (GRCm39) |
I289N |
probably damaging |
Het |
| Myh6 |
C |
T |
14: 55,190,118 (GRCm39) |
R1055Q |
probably damaging |
Het |
| Myh7 |
T |
C |
14: 55,216,965 (GRCm39) |
K1131E |
probably damaging |
Het |
| Ndrg3 |
A |
T |
2: 156,773,125 (GRCm39) |
|
probably benign |
Het |
| Nid2 |
A |
G |
14: 19,818,276 (GRCm39) |
|
probably null |
Het |
| Nup188 |
A |
T |
2: 30,220,761 (GRCm39) |
S945C |
probably damaging |
Het |
| Or1j21 |
A |
G |
2: 36,683,685 (GRCm39) |
M146V |
probably benign |
Het |
| Or5g23 |
C |
T |
2: 85,438,817 (GRCm39) |
V146I |
probably benign |
Het |
| Or8c11 |
A |
G |
9: 38,289,213 (GRCm39) |
N12S |
probably benign |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Patl2 |
A |
G |
2: 121,959,368 (GRCm39) |
L32P |
probably damaging |
Het |
| Pcdh20 |
T |
A |
14: 88,705,813 (GRCm39) |
M496L |
probably benign |
Het |
| Pdzd2 |
A |
G |
15: 12,373,028 (GRCm39) |
V2369A |
possibly damaging |
Het |
| Pfn2 |
A |
G |
3: 57,754,812 (GRCm39) |
V31A |
probably damaging |
Het |
| Plxna4 |
T |
C |
6: 32,228,007 (GRCm39) |
N533S |
probably benign |
Het |
| Plxnb1 |
T |
C |
9: 108,943,661 (GRCm39) |
F1916S |
probably damaging |
Het |
| Ppp4r3b |
T |
C |
11: 29,138,293 (GRCm39) |
F214L |
probably benign |
Het |
| Prox1 |
T |
C |
1: 189,893,638 (GRCm39) |
D269G |
probably benign |
Het |
| Rapgef4 |
T |
C |
2: 71,864,378 (GRCm39) |
F71S |
probably damaging |
Het |
| Rft1 |
A |
G |
14: 30,383,243 (GRCm39) |
I94M |
probably benign |
Het |
| S100z |
T |
C |
13: 95,615,127 (GRCm39) |
I13V |
probably damaging |
Het |
| Serhl |
T |
A |
15: 82,986,835 (GRCm39) |
V117E |
probably damaging |
Het |
| Shroom1 |
G |
A |
11: 53,356,334 (GRCm39) |
R336Q |
probably benign |
Het |
| Sik3 |
A |
T |
9: 46,123,552 (GRCm39) |
Q1067L |
probably damaging |
Het |
| Slc22a30 |
G |
A |
19: 8,321,757 (GRCm39) |
Q436* |
probably null |
Het |
| Slc28a1 |
G |
A |
7: 80,771,869 (GRCm39) |
V118M |
probably damaging |
Het |
| Slco1a6 |
T |
A |
6: 142,078,427 (GRCm39) |
I153F |
probably benign |
Het |
| Ss18l1 |
T |
C |
2: 179,703,735 (GRCm39) |
Y323H |
unknown |
Het |
| Susd4 |
G |
T |
1: 182,719,824 (GRCm39) |
A480S |
possibly damaging |
Het |
| Syne3 |
A |
T |
12: 104,942,139 (GRCm39) |
M1K |
probably null |
Het |
| Synpo2l |
A |
T |
14: 20,711,082 (GRCm39) |
S513T |
probably benign |
Het |
| Tat |
A |
T |
8: 110,724,966 (GRCm39) |
N388I |
probably benign |
Het |
| Tbc1d1 |
A |
G |
5: 64,439,352 (GRCm39) |
Y619C |
probably damaging |
Het |
| Tbk1 |
G |
A |
10: 121,406,590 (GRCm39) |
T216M |
probably damaging |
Het |
| Tns1 |
C |
T |
1: 74,034,585 (GRCm39) |
|
probably benign |
Het |
| Trbv5 |
T |
C |
6: 41,039,318 (GRCm39) |
V9A |
possibly damaging |
Het |
| Trpm5 |
A |
G |
7: 142,636,040 (GRCm39) |
Y575H |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,570,045 (GRCm39) |
Y25203* |
probably null |
Het |
| Tubb3 |
C |
A |
8: 124,148,391 (GRCm39) |
D441E |
probably benign |
Het |
| Usp33 |
T |
A |
3: 152,097,333 (GRCm39) |
C850* |
probably null |
Het |
| Vdac1 |
G |
A |
11: 52,274,905 (GRCm39) |
|
probably null |
Het |
| Vmn1r232 |
T |
C |
17: 21,133,846 (GRCm39) |
I251M |
probably damaging |
Het |
| Vmn2r11 |
T |
G |
5: 109,202,658 (GRCm39) |
I140L |
probably benign |
Het |
| Vmn2r6 |
A |
T |
3: 64,464,263 (GRCm39) |
N190K |
probably benign |
Het |
| Vps51 |
T |
A |
19: 6,120,518 (GRCm39) |
H465L |
probably benign |
Het |
| Zfp318 |
T |
G |
17: 46,722,995 (GRCm39) |
I1666S |
probably benign |
Het |
| Zfp446 |
C |
T |
7: 12,713,231 (GRCm39) |
R90* |
probably null |
Het |
| Zgrf1 |
T |
A |
3: 127,396,094 (GRCm39) |
F547I |
probably damaging |
Het |
|
| Other mutations in Nebl |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02146:Nebl
|
APN |
2 |
17,353,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02732:Nebl
|
APN |
2 |
17,457,295 (GRCm39) |
splice site |
probably benign |
|
|
IGL03241:Nebl
|
APN |
2 |
17,397,975 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03334:Nebl
|
APN |
2 |
17,418,522 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB008:Nebl
|
UTSW |
2 |
17,381,433 (GRCm39) |
critical splice donor site |
probably null |
|
|
BB018:Nebl
|
UTSW |
2 |
17,381,433 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0068:Nebl
|
UTSW |
2 |
17,439,782 (GRCm39) |
nonsense |
probably null |
|
|
R0127:Nebl
|
UTSW |
2 |
17,397,794 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0128:Nebl
|
UTSW |
2 |
17,397,834 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0130:Nebl
|
UTSW |
2 |
17,397,834 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0130:Nebl
|
UTSW |
2 |
17,395,737 (GRCm39) |
start gained |
probably benign |
|
|
R0537:Nebl
|
UTSW |
2 |
17,409,026 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R0743:Nebl
|
UTSW |
2 |
17,415,929 (GRCm39) |
missense |
probably benign |
|
|
R0884:Nebl
|
UTSW |
2 |
17,415,929 (GRCm39) |
missense |
probably benign |
|
|
R1364:Nebl
|
UTSW |
2 |
17,397,848 (GRCm39) |
unclassified |
probably benign |
|
|
R1638:Nebl
|
UTSW |
2 |
17,381,462 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1711:Nebl
|
UTSW |
2 |
17,393,565 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1933:Nebl
|
UTSW |
2 |
17,380,103 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1990:Nebl
|
UTSW |
2 |
17,457,321 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1991:Nebl
|
UTSW |
2 |
17,457,321 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1992:Nebl
|
UTSW |
2 |
17,457,321 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2062:Nebl
|
UTSW |
2 |
17,401,932 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2183:Nebl
|
UTSW |
2 |
17,409,027 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2325:Nebl
|
UTSW |
2 |
17,397,827 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2679:Nebl
|
UTSW |
2 |
17,429,402 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2877:Nebl
|
UTSW |
2 |
17,439,740 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2878:Nebl
|
UTSW |
2 |
17,439,740 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3079:Nebl
|
UTSW |
2 |
17,381,462 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3080:Nebl
|
UTSW |
2 |
17,381,462 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3878:Nebl
|
UTSW |
2 |
17,398,063 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3947:Nebl
|
UTSW |
2 |
17,382,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4983:Nebl
|
UTSW |
2 |
17,380,082 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5006:Nebl
|
UTSW |
2 |
17,393,582 (GRCm39) |
splice site |
probably null |
|
|
R5491:Nebl
|
UTSW |
2 |
17,439,783 (GRCm39) |
nonsense |
probably null |
|
|
R5533:Nebl
|
UTSW |
2 |
17,398,079 (GRCm39) |
nonsense |
probably null |
|
|
R5597:Nebl
|
UTSW |
2 |
17,382,978 (GRCm39) |
missense |
probably benign |
|
|
R5658:Nebl
|
UTSW |
2 |
17,353,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5933:Nebl
|
UTSW |
2 |
17,408,998 (GRCm39) |
missense |
probably benign |
|
|
R6056:Nebl
|
UTSW |
2 |
17,455,045 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6161:Nebl
|
UTSW |
2 |
17,735,641 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6646:Nebl
|
UTSW |
2 |
17,381,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Nebl
|
UTSW |
2 |
17,439,725 (GRCm39) |
nonsense |
probably null |
|
|
R6935:Nebl
|
UTSW |
2 |
17,353,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Nebl
|
UTSW |
2 |
17,457,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7671:Nebl
|
UTSW |
2 |
17,395,727 (GRCm39) |
nonsense |
probably null |
|
|
R7728:Nebl
|
UTSW |
2 |
17,375,325 (GRCm39) |
missense |
|
|
|
R7931:Nebl
|
UTSW |
2 |
17,381,433 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8007:Nebl
|
UTSW |
2 |
17,375,300 (GRCm39) |
missense |
|
|
|
R8048:Nebl
|
UTSW |
2 |
17,429,333 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8118:Nebl
|
UTSW |
2 |
17,384,631 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8317:Nebl
|
UTSW |
2 |
17,355,568 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8349:Nebl
|
UTSW |
2 |
17,418,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8360:Nebl
|
UTSW |
2 |
17,465,298 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8392:Nebl
|
UTSW |
2 |
17,457,363 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8449:Nebl
|
UTSW |
2 |
17,418,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8537:Nebl
|
UTSW |
2 |
17,355,520 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8778:Nebl
|
UTSW |
2 |
17,409,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Nebl
|
UTSW |
2 |
17,735,671 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R8894:Nebl
|
UTSW |
2 |
17,380,036 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8906:Nebl
|
UTSW |
2 |
17,382,928 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8929:Nebl
|
UTSW |
2 |
17,397,991 (GRCm39) |
nonsense |
probably null |
|
|
R9054:Nebl
|
UTSW |
2 |
17,415,907 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9119:Nebl
|
UTSW |
2 |
17,405,370 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9211:Nebl
|
UTSW |
2 |
17,393,501 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9225:Nebl
|
UTSW |
2 |
17,405,322 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9296:Nebl
|
UTSW |
2 |
17,429,451 (GRCm39) |
splice site |
probably benign |
|
|
R9310:Nebl
|
UTSW |
2 |
17,353,678 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9474:Nebl
|
UTSW |
2 |
17,374,421 (GRCm39) |
nonsense |
probably null |
|
|
X0012:Nebl
|
UTSW |
2 |
17,448,605 (GRCm39) |
missense |
probably benign |
0.16 |
|
X0025:Nebl
|
UTSW |
2 |
17,409,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTAGCTTCAGAAACATTACCTTGG -3'
(R):5'- TGATGATGGCTGGCTACATAG -3'
Sequencing Primer
(F):5'- ACATTACCTTGGTTTATTCTTGCAG -3'
(R):5'- GGCTGGCTACATAGGTTAAAATAC -3'
|
| Posted On |
2016-07-06 |
Incidental Mutation