Incidental Mutation 'R5256:Plxnb1'
| ID |
399674 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
042827-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5256 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 108943661 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 1916
(F1916S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072093
AA Change: F1916S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: F1916S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Meta Mutation Damage Score |
0.8458 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.8%
|
| Validation Efficiency |
97% (95/98) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730015C16Rik |
C |
A |
4: 108,705,262 (GRCm39) |
|
probably benign |
Het |
| Actr1b |
T |
C |
1: 36,739,173 (GRCm39) |
H372R |
probably benign |
Het |
| Ampd2 |
C |
A |
3: 107,986,865 (GRCm39) |
|
probably benign |
Het |
| Anapc4 |
A |
G |
5: 53,020,936 (GRCm39) |
S612G |
probably benign |
Het |
| Arhgef7 |
T |
C |
8: 11,850,811 (GRCm39) |
L141P |
probably damaging |
Het |
| Atl1 |
A |
G |
12: 70,006,107 (GRCm39) |
D471G |
probably damaging |
Het |
| Atrn |
A |
G |
2: 130,787,939 (GRCm39) |
D247G |
probably benign |
Het |
| Bag1 |
T |
A |
4: 40,948,022 (GRCm39) |
R61W |
probably damaging |
Het |
| Card10 |
C |
T |
15: 78,662,451 (GRCm39) |
R898H |
probably damaging |
Het |
| Cct6b |
G |
A |
11: 82,655,046 (GRCm39) |
A3V |
probably damaging |
Het |
| Cfap54 |
A |
T |
10: 92,770,953 (GRCm39) |
L2097* |
probably null |
Het |
| Cfap54 |
T |
C |
10: 92,880,885 (GRCm39) |
|
probably null |
Het |
| Chd5 |
T |
C |
4: 152,456,554 (GRCm39) |
F964L |
probably benign |
Het |
| Cog5 |
A |
G |
12: 31,936,204 (GRCm39) |
T584A |
probably benign |
Het |
| Cpa2 |
T |
A |
6: 30,547,196 (GRCm39) |
N157K |
probably damaging |
Het |
| Cpeb1 |
A |
T |
7: 81,001,587 (GRCm39) |
M440K |
probably damaging |
Het |
| Cracr2a |
G |
A |
6: 127,580,992 (GRCm39) |
C56Y |
probably damaging |
Het |
| Ddb2 |
A |
C |
2: 91,067,073 (GRCm39) |
L30R |
probably damaging |
Het |
| Dlk1 |
T |
A |
12: 109,425,697 (GRCm39) |
I190N |
probably damaging |
Het |
| Dnaaf4 |
T |
C |
9: 72,879,362 (GRCm39) |
|
probably null |
Het |
| Dnajc13 |
T |
A |
9: 104,080,528 (GRCm39) |
Y851F |
possibly damaging |
Het |
| Dop1a |
T |
A |
9: 86,397,381 (GRCm39) |
L895Q |
probably damaging |
Het |
| F7 |
G |
A |
8: 13,080,763 (GRCm39) |
C122Y |
probably damaging |
Het |
| Frrs1 |
T |
C |
3: 116,696,749 (GRCm39) |
V573A |
possibly damaging |
Het |
| Galnt2l |
T |
C |
8: 122,997,175 (GRCm39) |
|
probably benign |
Het |
| Gm17541 |
A |
T |
12: 4,739,672 (GRCm39) |
|
probably benign |
Het |
| Gm5519 |
A |
T |
19: 33,800,576 (GRCm39) |
H90L |
probably damaging |
Het |
| Gm5526 |
T |
A |
1: 45,896,569 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5709 |
A |
T |
3: 59,509,971 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
T |
A |
9: 118,385,569 (GRCm39) |
V869D |
possibly damaging |
Het |
| Grm7 |
A |
T |
6: 111,335,182 (GRCm39) |
Q531L |
probably benign |
Het |
| Hnrnpu |
C |
A |
1: 178,163,458 (GRCm39) |
C265F |
unknown |
Het |
| Hoxd3 |
G |
A |
2: 74,577,211 (GRCm39) |
V364I |
possibly damaging |
Het |
| Hspb8 |
T |
C |
5: 116,547,532 (GRCm39) |
D150G |
probably damaging |
Het |
| Hydin |
C |
A |
8: 111,313,855 (GRCm39) |
N4244K |
possibly damaging |
Het |
| Ik |
A |
G |
18: 36,881,926 (GRCm39) |
D136G |
probably benign |
Het |
| Il11ra1 |
T |
C |
4: 41,767,932 (GRCm39) |
|
probably benign |
Het |
| Jph1 |
T |
C |
1: 17,161,622 (GRCm39) |
I347V |
probably benign |
Het |
| Klk1 |
T |
A |
7: 43,870,985 (GRCm39) |
|
probably benign |
Het |
| Lmcd1 |
T |
A |
6: 112,265,087 (GRCm39) |
|
probably benign |
Het |
| Lnx1 |
C |
T |
5: 74,846,315 (GRCm39) |
C45Y |
probably damaging |
Het |
| Macc1 |
T |
A |
12: 119,410,264 (GRCm39) |
M344K |
possibly damaging |
Het |
| Madcam1 |
A |
G |
10: 79,500,779 (GRCm39) |
E32G |
possibly damaging |
Het |
| Mat2a |
T |
C |
6: 72,411,316 (GRCm39) |
D383G |
probably benign |
Het |
| Mpst |
T |
A |
15: 78,297,849 (GRCm39) |
I289N |
probably damaging |
Het |
| Myh6 |
C |
T |
14: 55,190,118 (GRCm39) |
R1055Q |
probably damaging |
Het |
| Myh7 |
T |
C |
14: 55,216,965 (GRCm39) |
K1131E |
probably damaging |
Het |
| Ndrg3 |
A |
T |
2: 156,773,125 (GRCm39) |
|
probably benign |
Het |
| Nebl |
A |
G |
2: 17,438,786 (GRCm39) |
S209P |
probably benign |
Het |
| Nid2 |
A |
G |
14: 19,818,276 (GRCm39) |
|
probably null |
Het |
| Nup188 |
A |
T |
2: 30,220,761 (GRCm39) |
S945C |
probably damaging |
Het |
| Or1j21 |
A |
G |
2: 36,683,685 (GRCm39) |
M146V |
probably benign |
Het |
| Or5g23 |
C |
T |
2: 85,438,817 (GRCm39) |
V146I |
probably benign |
Het |
| Or8c11 |
A |
G |
9: 38,289,213 (GRCm39) |
N12S |
probably benign |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Patl2 |
A |
G |
2: 121,959,368 (GRCm39) |
L32P |
probably damaging |
Het |
| Pcdh20 |
T |
A |
14: 88,705,813 (GRCm39) |
M496L |
probably benign |
Het |
| Pdzd2 |
A |
G |
15: 12,373,028 (GRCm39) |
V2369A |
possibly damaging |
Het |
| Pfn2 |
A |
G |
3: 57,754,812 (GRCm39) |
V31A |
probably damaging |
Het |
| Plxna4 |
T |
C |
6: 32,228,007 (GRCm39) |
N533S |
probably benign |
Het |
| Ppp4r3b |
T |
C |
11: 29,138,293 (GRCm39) |
F214L |
probably benign |
Het |
| Prox1 |
T |
C |
1: 189,893,638 (GRCm39) |
D269G |
probably benign |
Het |
| Rapgef4 |
T |
C |
2: 71,864,378 (GRCm39) |
F71S |
probably damaging |
Het |
| Rft1 |
A |
G |
14: 30,383,243 (GRCm39) |
I94M |
probably benign |
Het |
| S100z |
T |
C |
13: 95,615,127 (GRCm39) |
I13V |
probably damaging |
Het |
| Serhl |
T |
A |
15: 82,986,835 (GRCm39) |
V117E |
probably damaging |
Het |
| Shroom1 |
G |
A |
11: 53,356,334 (GRCm39) |
R336Q |
probably benign |
Het |
| Sik3 |
A |
T |
9: 46,123,552 (GRCm39) |
Q1067L |
probably damaging |
Het |
| Slc22a30 |
G |
A |
19: 8,321,757 (GRCm39) |
Q436* |
probably null |
Het |
| Slc28a1 |
G |
A |
7: 80,771,869 (GRCm39) |
V118M |
probably damaging |
Het |
| Slco1a6 |
T |
A |
6: 142,078,427 (GRCm39) |
I153F |
probably benign |
Het |
| Ss18l1 |
T |
C |
2: 179,703,735 (GRCm39) |
Y323H |
unknown |
Het |
| Susd4 |
G |
T |
1: 182,719,824 (GRCm39) |
A480S |
possibly damaging |
Het |
| Syne3 |
A |
T |
12: 104,942,139 (GRCm39) |
M1K |
probably null |
Het |
| Synpo2l |
A |
T |
14: 20,711,082 (GRCm39) |
S513T |
probably benign |
Het |
| Tat |
A |
T |
8: 110,724,966 (GRCm39) |
N388I |
probably benign |
Het |
| Tbc1d1 |
A |
G |
5: 64,439,352 (GRCm39) |
Y619C |
probably damaging |
Het |
| Tbk1 |
G |
A |
10: 121,406,590 (GRCm39) |
T216M |
probably damaging |
Het |
| Tns1 |
C |
T |
1: 74,034,585 (GRCm39) |
|
probably benign |
Het |
| Trbv5 |
T |
C |
6: 41,039,318 (GRCm39) |
V9A |
possibly damaging |
Het |
| Trpm5 |
A |
G |
7: 142,636,040 (GRCm39) |
Y575H |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,570,045 (GRCm39) |
Y25203* |
probably null |
Het |
| Tubb3 |
C |
A |
8: 124,148,391 (GRCm39) |
D441E |
probably benign |
Het |
| Usp33 |
T |
A |
3: 152,097,333 (GRCm39) |
C850* |
probably null |
Het |
| Vdac1 |
G |
A |
11: 52,274,905 (GRCm39) |
|
probably null |
Het |
| Vmn1r232 |
T |
C |
17: 21,133,846 (GRCm39) |
I251M |
probably damaging |
Het |
| Vmn2r11 |
T |
G |
5: 109,202,658 (GRCm39) |
I140L |
probably benign |
Het |
| Vmn2r6 |
A |
T |
3: 64,464,263 (GRCm39) |
N190K |
probably benign |
Het |
| Vps51 |
T |
A |
19: 6,120,518 (GRCm39) |
H465L |
probably benign |
Het |
| Zfp318 |
T |
G |
17: 46,722,995 (GRCm39) |
I1666S |
probably benign |
Het |
| Zfp446 |
C |
T |
7: 12,713,231 (GRCm39) |
R90* |
probably null |
Het |
| Zgrf1 |
T |
A |
3: 127,396,094 (GRCm39) |
F547I |
probably damaging |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- GACACGCCTGCTATCCATGAAG -3'
(R):5'- AGTAACTGTGCTGTGGAGGC -3'
Sequencing Primer
(F):5'- CCTGCTATCCATGAAGGTGGG -3'
(R):5'- GCCCCCACATATGTCCTGAG -3'
|
| Posted On |
2016-07-06 |
Incidental Mutation