Incidental Mutation 'R5267:Dsc2'
| ID |
401808 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
042859-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5267 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 20167640 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000039247
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000075214
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000075214
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000155407
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9495 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.8%
|
| Validation Efficiency |
98% (86/88) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca12 |
T |
A |
1: 71,374,933 (GRCm39) |
|
probably benign |
Het |
| Adam15 |
T |
G |
3: 89,257,206 (GRCm39) |
|
probably benign |
Het |
| Albfm1 |
T |
C |
5: 90,732,716 (GRCm39) |
F509S |
probably damaging |
Het |
| Atp12a |
T |
C |
14: 56,621,668 (GRCm39) |
S768P |
probably damaging |
Het |
| Atp8a1 |
G |
A |
5: 67,919,887 (GRCm39) |
T393I |
probably damaging |
Het |
| B4galnt4 |
T |
G |
7: 140,650,524 (GRCm39) |
I3S |
probably damaging |
Het |
| Bfsp1 |
G |
A |
2: 143,668,971 (GRCm39) |
T536I |
probably benign |
Het |
| Brsk1 |
G |
T |
7: 4,707,708 (GRCm39) |
W284L |
probably damaging |
Het |
| Cadm3 |
A |
T |
1: 173,164,669 (GRCm39) |
D370E |
probably damaging |
Het |
| Cadps2 |
A |
G |
6: 23,626,667 (GRCm39) |
I207T |
possibly damaging |
Het |
| Calr4 |
A |
C |
4: 109,101,273 (GRCm39) |
T52P |
probably damaging |
Het |
| Catsperg2 |
G |
A |
7: 29,416,491 (GRCm39) |
T307M |
probably damaging |
Het |
| Ckap5 |
T |
A |
2: 91,422,097 (GRCm39) |
N1166K |
probably null |
Het |
| Clca4a |
G |
A |
3: 144,659,573 (GRCm39) |
T761I |
probably damaging |
Het |
| Cnksr3 |
A |
T |
10: 7,076,633 (GRCm39) |
|
probably null |
Het |
| Diaph3 |
A |
G |
14: 86,893,989 (GRCm39) |
S7P |
probably benign |
Het |
| Dnah7a |
G |
A |
1: 53,518,851 (GRCm39) |
P2969S |
probably damaging |
Het |
| Dnai2 |
A |
T |
11: 114,631,293 (GRCm39) |
T221S |
probably benign |
Het |
| Eif4g1 |
A |
G |
16: 20,504,283 (GRCm39) |
N789S |
probably damaging |
Het |
| Fn1 |
C |
T |
1: 71,668,863 (GRCm39) |
R694H |
probably damaging |
Het |
| Gm5478 |
G |
A |
15: 101,552,837 (GRCm39) |
R365C |
probably damaging |
Het |
| Gm5591 |
A |
T |
7: 38,218,338 (GRCm39) |
M845K |
possibly damaging |
Het |
| Gm5800 |
A |
T |
14: 51,951,294 (GRCm39) |
|
probably null |
Het |
| Gprc5c |
G |
T |
11: 114,755,093 (GRCm39) |
V257L |
possibly damaging |
Het |
| H2-Q2 |
A |
T |
17: 35,562,155 (GRCm39) |
Y134F |
probably benign |
Het |
| Hcfc1r1 |
A |
G |
17: 23,893,648 (GRCm39) |
R76G |
possibly damaging |
Het |
| Hectd4 |
T |
C |
5: 121,482,887 (GRCm39) |
I3146T |
probably benign |
Het |
| Herc1 |
G |
T |
9: 66,369,091 (GRCm39) |
L2928F |
probably damaging |
Het |
| Hmx3 |
C |
T |
7: 131,145,898 (GRCm39) |
A202V |
probably benign |
Het |
| Ikzf3 |
A |
T |
11: 98,381,406 (GRCm39) |
M58K |
probably benign |
Het |
| Il20ra |
A |
G |
10: 19,625,107 (GRCm39) |
T129A |
probably damaging |
Het |
| Il21 |
T |
C |
3: 37,281,946 (GRCm39) |
H66R |
probably benign |
Het |
| Kcnh5 |
A |
T |
12: 75,134,190 (GRCm39) |
M453K |
probably damaging |
Het |
| Kdf1 |
C |
G |
4: 133,256,258 (GRCm39) |
A325G |
probably damaging |
Het |
| Klhl10 |
C |
T |
11: 100,338,047 (GRCm39) |
A262V |
probably benign |
Het |
| Krt81 |
T |
A |
15: 101,357,340 (GRCm39) |
N464I |
probably benign |
Het |
| Ksr1 |
A |
T |
11: 78,911,251 (GRCm39) |
I698N |
probably damaging |
Het |
| Lrp2 |
A |
G |
2: 69,379,322 (GRCm39) |
V130A |
possibly damaging |
Het |
| Mcm2 |
T |
C |
6: 88,874,432 (GRCm39) |
T25A |
probably benign |
Het |
| Mrps18c |
T |
A |
5: 100,950,960 (GRCm39) |
Y93* |
probably null |
Het |
| Mycl |
C |
T |
4: 122,894,289 (GRCm39) |
A363V |
probably damaging |
Het |
| Mylk2 |
C |
A |
2: 152,755,469 (GRCm39) |
A211E |
probably benign |
Het |
| Myo5a |
G |
A |
9: 75,059,292 (GRCm39) |
D507N |
probably damaging |
Het |
| Myo7b |
A |
G |
18: 32,131,787 (GRCm39) |
F470L |
probably damaging |
Het |
| Oas1a |
A |
T |
5: 121,037,284 (GRCm39) |
C248S |
probably benign |
Het |
| Or2ag2b |
T |
C |
7: 106,418,015 (GRCm39) |
S242P |
probably damaging |
Het |
| Or4c15b |
C |
T |
2: 89,112,574 (GRCm39) |
W301* |
probably null |
Het |
| Or51aa2 |
T |
C |
7: 103,188,031 (GRCm39) |
I137V |
probably benign |
Het |
| Or5b116 |
A |
G |
19: 13,422,475 (GRCm39) |
Y33C |
probably damaging |
Het |
| Or5m9b |
T |
A |
2: 85,905,882 (GRCm39) |
V266E |
probably benign |
Het |
| Or5p67 |
A |
G |
7: 107,922,185 (GRCm39) |
S233P |
probably damaging |
Het |
| Or8d1 |
G |
A |
9: 38,767,101 (GRCm39) |
V248M |
probably damaging |
Het |
| Otub1 |
C |
A |
19: 7,177,357 (GRCm39) |
G67C |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Paqr8 |
A |
G |
1: 21,004,920 (GRCm39) |
I25V |
probably benign |
Het |
| Pcdh1 |
A |
G |
18: 38,325,252 (GRCm39) |
Y897H |
probably damaging |
Het |
| Pde4d |
T |
G |
13: 109,397,343 (GRCm39) |
|
probably benign |
Het |
| Pdzd8 |
C |
A |
19: 59,289,458 (GRCm39) |
K647N |
probably damaging |
Het |
| Pnkp |
C |
T |
7: 44,511,827 (GRCm39) |
S113L |
probably damaging |
Het |
| Praf2 |
T |
C |
X: 7,596,641 (GRCm39) |
|
probably benign |
Het |
| Pramel29 |
A |
T |
4: 143,939,575 (GRCm39) |
|
probably benign |
Het |
| Psg25 |
A |
T |
7: 18,258,711 (GRCm39) |
Y322N |
possibly damaging |
Het |
| Rxrg |
A |
G |
1: 167,463,335 (GRCm39) |
E402G |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,692,022 (GRCm39) |
V20E |
probably benign |
Het |
| Sipa1 |
G |
A |
19: 5,705,786 (GRCm39) |
T394I |
probably benign |
Het |
| Spag17 |
A |
T |
3: 99,969,264 (GRCm39) |
N1247I |
probably damaging |
Het |
| Spata31d1c |
A |
G |
13: 65,183,718 (GRCm39) |
D420G |
probably damaging |
Het |
| Syk |
A |
G |
13: 52,795,962 (GRCm39) |
K519R |
probably benign |
Het |
| Syne2 |
A |
T |
12: 75,985,515 (GRCm39) |
E1654D |
possibly damaging |
Het |
| Tha1 |
A |
C |
11: 117,760,502 (GRCm39) |
S241A |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,379,601 (GRCm39) |
E941V |
probably damaging |
Het |
| Tjp1 |
T |
C |
7: 64,972,797 (GRCm39) |
T548A |
probably damaging |
Het |
| Tube1 |
C |
A |
10: 39,020,552 (GRCm39) |
D210E |
probably benign |
Het |
| Vmn1r183 |
T |
A |
7: 23,754,971 (GRCm39) |
I258N |
possibly damaging |
Het |
| Vmn1r89 |
A |
T |
7: 12,954,140 (GRCm39) |
N292I |
probably damaging |
Het |
| Vmp1 |
C |
A |
11: 86,554,377 (GRCm39) |
V79L |
probably benign |
Het |
| Zfp182 |
T |
A |
X: 20,902,605 (GRCm39) |
D125V |
possibly damaging |
Het |
| Zfp975 |
T |
G |
7: 42,311,654 (GRCm39) |
T320P |
probably damaging |
Het |
| Znrf1 |
G |
A |
8: 112,263,899 (GRCm39) |
A43T |
probably benign |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,184,283 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,168,520 (GRCm39) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,373 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,183,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATGTGCGCTAGAGGATTG -3'
(R):5'- ATTTGATGAGACACTTACAGGAGC -3'
Sequencing Primer
(F):5'- GTAGCACAGCATGTCCAAACTGAG -3'
(R):5'- ATGAGACACTTACAGGAGCCTCTTTC -3'
|
| Posted On |
2016-07-06 |
Incidental Mutation