Incidental Mutation 'R5267:Dsc2'
| ID |
401808 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2b, Dsc2a |
| MMRRC Submission |
042859-MU
|
| Accession Numbers |
Genbank: NM_013505; MGI: 103221 |
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5267 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20030633-20059554 bp(-) (GRCm38) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 20034583 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000039247
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000075214
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000075214
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000155407
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9495 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.8%
|
| Validation Efficiency |
98% (86/88) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5830473C10Rik |
T |
C |
5: 90,584,857 (GRCm38) |
F509S |
probably damaging |
Het |
| Abca12 |
T |
A |
1: 71,335,774 (GRCm38) |
|
probably benign |
Het |
| Adam15 |
T |
G |
3: 89,349,899 (GRCm38) |
|
probably benign |
Het |
| Atp12a |
T |
C |
14: 56,384,211 (GRCm38) |
S768P |
probably damaging |
Het |
| Atp8a1 |
G |
A |
5: 67,762,544 (GRCm38) |
T393I |
probably damaging |
Het |
| B4galnt4 |
T |
G |
7: 141,070,611 (GRCm38) |
I3S |
probably damaging |
Het |
| Bfsp1 |
G |
A |
2: 143,827,051 (GRCm38) |
T536I |
probably benign |
Het |
| Brsk1 |
G |
T |
7: 4,704,709 (GRCm38) |
W284L |
probably damaging |
Het |
| C87977 |
A |
T |
4: 144,213,005 (GRCm38) |
|
probably benign |
Het |
| Cadm3 |
A |
T |
1: 173,337,102 (GRCm38) |
D370E |
probably damaging |
Het |
| Cadps2 |
A |
G |
6: 23,626,668 (GRCm38) |
I207T |
possibly damaging |
Het |
| Calr4 |
A |
C |
4: 109,244,076 (GRCm38) |
T52P |
probably damaging |
Het |
| Catsperg2 |
G |
A |
7: 29,717,066 (GRCm38) |
T307M |
probably damaging |
Het |
| Ckap5 |
T |
A |
2: 91,591,752 (GRCm38) |
N1166K |
probably null |
Het |
| Clca4a |
G |
A |
3: 144,953,812 (GRCm38) |
T761I |
probably damaging |
Het |
| Cnksr3 |
A |
T |
10: 7,126,633 (GRCm38) |
|
probably null |
Het |
| Diaph3 |
A |
G |
14: 86,656,553 (GRCm38) |
S7P |
probably benign |
Het |
| Dnah7a |
G |
A |
1: 53,479,692 (GRCm38) |
P2969S |
probably damaging |
Het |
| Dnaic2 |
A |
T |
11: 114,740,467 (GRCm38) |
T221S |
probably benign |
Het |
| Eif4g1 |
A |
G |
16: 20,685,533 (GRCm38) |
N789S |
probably damaging |
Het |
| Fn1 |
C |
T |
1: 71,629,704 (GRCm38) |
R694H |
probably damaging |
Het |
| Gm5478 |
G |
A |
15: 101,644,402 (GRCm38) |
R365C |
probably damaging |
Het |
| Gm5591 |
A |
T |
7: 38,518,914 (GRCm38) |
M845K |
possibly damaging |
Het |
| Gm5800 |
A |
T |
14: 51,713,837 (GRCm38) |
|
probably null |
Het |
| Gprc5c |
G |
T |
11: 114,864,267 (GRCm38) |
V257L |
possibly damaging |
Het |
| H2-Q2 |
A |
T |
17: 35,343,179 (GRCm38) |
Y134F |
probably benign |
Het |
| Hcfc1r1 |
A |
G |
17: 23,674,674 (GRCm38) |
R76G |
possibly damaging |
Het |
| Hectd4 |
T |
C |
5: 121,344,824 (GRCm38) |
I3146T |
probably benign |
Het |
| Herc1 |
G |
T |
9: 66,461,809 (GRCm38) |
L2928F |
probably damaging |
Het |
| Hmx3 |
C |
T |
7: 131,544,169 (GRCm38) |
A202V |
probably benign |
Het |
| Ikzf3 |
A |
T |
11: 98,490,580 (GRCm38) |
M58K |
probably benign |
Het |
| Il20ra |
A |
G |
10: 19,749,359 (GRCm38) |
T129A |
probably damaging |
Het |
| Il21 |
T |
C |
3: 37,227,797 (GRCm38) |
H66R |
probably benign |
Het |
| Kcnh5 |
A |
T |
12: 75,087,416 (GRCm38) |
M453K |
probably damaging |
Het |
| Kdf1 |
C |
G |
4: 133,528,947 (GRCm38) |
A325G |
probably damaging |
Het |
| Klhl10 |
C |
T |
11: 100,447,221 (GRCm38) |
A262V |
probably benign |
Het |
| Krt81 |
T |
A |
15: 101,459,459 (GRCm38) |
N464I |
probably benign |
Het |
| Ksr1 |
A |
T |
11: 79,020,425 (GRCm38) |
I698N |
probably damaging |
Het |
| Lrp2 |
A |
G |
2: 69,548,978 (GRCm38) |
V130A |
possibly damaging |
Het |
| Mcm2 |
T |
C |
6: 88,897,450 (GRCm38) |
T25A |
probably benign |
Het |
| Mrps18c |
T |
A |
5: 100,803,094 (GRCm38) |
Y93* |
probably null |
Het |
| Mycl |
C |
T |
4: 123,000,496 (GRCm38) |
A363V |
probably damaging |
Het |
| Mylk2 |
C |
A |
2: 152,913,549 (GRCm38) |
A211E |
probably benign |
Het |
| Myo5a |
G |
A |
9: 75,152,010 (GRCm38) |
D507N |
probably damaging |
Het |
| Myo7b |
A |
G |
18: 31,998,734 (GRCm38) |
F470L |
probably damaging |
Het |
| Oas1a |
A |
T |
5: 120,899,221 (GRCm38) |
C248S |
probably benign |
Het |
| Olfr1036 |
T |
A |
2: 86,075,538 (GRCm38) |
V266E |
probably benign |
Het |
| Olfr1229 |
C |
T |
2: 89,282,230 (GRCm38) |
W301* |
probably null |
Het |
| Olfr1471 |
A |
G |
19: 13,445,111 (GRCm38) |
Y33C |
probably damaging |
Het |
| Olfr26 |
G |
A |
9: 38,855,805 (GRCm38) |
V248M |
probably damaging |
Het |
| Olfr492 |
A |
G |
7: 108,322,978 (GRCm38) |
S233P |
probably damaging |
Het |
| Olfr612 |
T |
C |
7: 103,538,824 (GRCm38) |
I137V |
probably benign |
Het |
| Olfr701 |
T |
C |
7: 106,818,808 (GRCm38) |
S242P |
probably damaging |
Het |
| Otub1 |
C |
A |
19: 7,199,992 (GRCm38) |
G67C |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,997,037 (GRCm38) |
A91S |
probably damaging |
Het |
| Paqr8 |
A |
G |
1: 20,934,696 (GRCm38) |
I25V |
probably benign |
Het |
| Pcdh1 |
A |
G |
18: 38,192,199 (GRCm38) |
Y897H |
probably damaging |
Het |
| Pde4d |
T |
G |
13: 109,260,809 (GRCm38) |
|
probably benign |
Het |
| Pdzd8 |
C |
A |
19: 59,301,026 (GRCm38) |
K647N |
probably damaging |
Het |
| Pnkp |
C |
T |
7: 44,862,403 (GRCm38) |
S113L |
probably damaging |
Het |
| Praf2 |
T |
C |
X: 7,730,402 (GRCm38) |
|
probably benign |
Het |
| Psg25 |
A |
T |
7: 18,524,786 (GRCm38) |
Y322N |
possibly damaging |
Het |
| Rxrg |
A |
G |
1: 167,635,766 (GRCm38) |
E402G |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,970,065 (GRCm38) |
V20E |
probably benign |
Het |
| Sipa1 |
G |
A |
19: 5,655,758 (GRCm38) |
T394I |
probably benign |
Het |
| Spag17 |
A |
T |
3: 100,061,948 (GRCm38) |
N1247I |
probably damaging |
Het |
| Spata31d1c |
A |
G |
13: 65,035,904 (GRCm38) |
D420G |
probably damaging |
Het |
| Syk |
A |
G |
13: 52,641,926 (GRCm38) |
K519R |
probably benign |
Het |
| Syne2 |
A |
T |
12: 75,938,741 (GRCm38) |
E1654D |
possibly damaging |
Het |
| Tha1 |
A |
C |
11: 117,869,676 (GRCm38) |
S241A |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,379,602 (GRCm38) |
E941V |
probably damaging |
Het |
| Tjp1 |
T |
C |
7: 65,323,049 (GRCm38) |
T548A |
probably damaging |
Het |
| Tube1 |
C |
A |
10: 39,144,556 (GRCm38) |
D210E |
probably benign |
Het |
| Vmn1r183 |
T |
A |
7: 24,055,546 (GRCm38) |
I258N |
possibly damaging |
Het |
| Vmn1r89 |
A |
T |
7: 13,220,213 (GRCm38) |
N292I |
probably damaging |
Het |
| Vmp1 |
C |
A |
11: 86,663,551 (GRCm38) |
V79L |
probably benign |
Het |
| Zfp182 |
T |
A |
X: 21,036,366 (GRCm38) |
D125V |
possibly damaging |
Het |
| Zfp975 |
T |
G |
7: 42,662,230 (GRCm38) |
T320P |
probably damaging |
Het |
| Znrf1 |
G |
A |
8: 111,537,267 (GRCm38) |
A43T |
probably benign |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,041,797 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,035,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,034,683 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,043,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,048,286 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,047,157 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,038,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,046,342 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,043,733 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,045,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,041,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,047,079 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,046,243 (GRCm38) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,046,277 (GRCm38) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,033,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,051,226 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,041,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,041,452 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,050,059 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,033,295 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,032,212 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,045,565 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,034,701 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,050,151 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,046,246 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,032,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,045,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,035,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,045,469 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,045,501 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,032,351 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,050,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,050,142 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5445:Dsc2
|
UTSW |
18 |
20,035,303 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,046,279 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,035,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,032,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,047,108 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,045,430 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,035,463 (GRCm38) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,051,175 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,046,238 (GRCm38) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,032,278 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,050,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,035,275 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,051,179 (GRCm38) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,035,335 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,041,926 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,035,394 (GRCm38) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,050,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,041,778 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,316 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,315 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,050,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,046,285 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,034,663 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,034,665 (GRCm38) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,038,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,043,911 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,034,707 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,041,716 (GRCm38) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,047,219 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,038,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,046,304 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,035,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATGTGCGCTAGAGGATTG -3'
(R):5'- ATTTGATGAGACACTTACAGGAGC -3'
Sequencing Primer
(F):5'- GTAGCACAGCATGTCCAAACTGAG -3'
(R):5'- ATGAGACACTTACAGGAGCCTCTTTC -3'
|
| Posted On |
2016-07-06 |
Incidental Mutation