Incidental Mutation 'R4726:Lrrc7'
| ID |
401826 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrrc7
|
| Ensembl Gene |
ENSMUSG00000028176 |
| Gene Name |
leucine rich repeat containing 7 |
| Synonyms |
densin |
| MMRRC Submission |
041989-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.748)
|
| Stock # |
R4726 (G1)
|
| Quality Score |
217 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
157788528-158267858 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site |
| DNA Base Change (assembly) |
GAAGTTGTTTGGAGATTCTTATCTTA to GA
at 158024045 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106044]
[ENSMUST00000199890]
[ENSMUST00000200137]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106044
|
| SMART Domains |
Protein: ENSMUSP00000101659
Gene: ENSMUSG00000028176
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1349 |
1378 |
2e-11 |
BLAST |
|
PDZ
|
1460 |
1540 |
1.33e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199890
|
| SMART Domains |
Protein: ENSMUSP00000142440
Gene: ENSMUSG00000028176
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
9e-6 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1328 |
1364 |
1e-15 |
BLAST |
|
low complexity region
|
1374 |
1387 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200137
|
| SMART Domains |
Protein: ENSMUSP00000142498
Gene: ENSMUSG00000028176
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
52 |
69 |
7.6e-1 |
SMART |
|
LRR
|
73 |
92 |
4.2e-1 |
SMART |
|
LRR
|
96 |
115 |
3.4e-1 |
SMART |
|
LRR
|
142 |
164 |
1.8e-1 |
SMART |
|
LRR
|
165 |
184 |
1.5e-1 |
SMART |
|
LRR
|
188 |
207 |
2e-2 |
SMART |
|
LRR
|
211 |
233 |
1.3e-1 |
SMART |
|
LRR
|
234 |
257 |
1.7e-1 |
SMART |
|
LRR
|
257 |
276 |
1e0 |
SMART |
|
LRR
|
280 |
299 |
3.1e-2 |
SMART |
|
LRR
|
303 |
322 |
6.6e-1 |
SMART |
|
LRR
|
326 |
345 |
2.1e-1 |
SMART |
|
LRR
|
372 |
391 |
1.2e-1 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1302 |
1331 |
2e-11 |
BLAST |
|
PDZ
|
1413 |
1493 |
6.4e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200196
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
99% (74/75) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit limb grasping, reduced long term depression, increased anxiety, increased aggression towards other mice, impaired spatial memory, decreased prepulse inhibition, decreased nesting building behavior, and abnormal dendritic spines. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(2) : Gene trapped(2) |
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930583I09Rik |
T |
C |
17: 65,141,448 (GRCm39) |
S52G |
probably null |
Het |
| Abcc2 |
T |
C |
19: 43,820,553 (GRCm39) |
S1351P |
probably benign |
Het |
| Acp2 |
T |
A |
2: 91,034,622 (GRCm39) |
L87Q |
probably damaging |
Het |
| Adgrl3 |
C |
A |
5: 81,794,425 (GRCm39) |
T550K |
possibly damaging |
Het |
| Amotl2 |
A |
G |
9: 102,601,018 (GRCm39) |
R329G |
probably benign |
Het |
| Angel1 |
T |
C |
12: 86,768,649 (GRCm39) |
N278S |
probably damaging |
Het |
| Ankrd12 |
A |
C |
17: 66,277,319 (GRCm39) |
M1985R |
probably damaging |
Het |
| Apob |
T |
A |
12: 8,040,267 (GRCm39) |
F535I |
probably damaging |
Het |
| Art3 |
A |
G |
5: 92,559,002 (GRCm39) |
K313R |
probably benign |
Het |
| Asxl2 |
C |
T |
12: 3,551,872 (GRCm39) |
H1205Y |
possibly damaging |
Het |
| Bsph1 |
A |
T |
7: 13,206,920 (GRCm39) |
M99L |
probably benign |
Het |
| Ccdc153 |
T |
C |
9: 44,154,963 (GRCm39) |
|
probably null |
Het |
| Cdh16 |
A |
T |
8: 105,342,664 (GRCm39) |
M28K |
probably damaging |
Het |
| Cdhr2 |
T |
C |
13: 54,866,352 (GRCm39) |
F353L |
probably damaging |
Het |
| Chrna2 |
G |
T |
14: 66,386,345 (GRCm39) |
V164L |
possibly damaging |
Het |
| Cip2a |
A |
G |
16: 48,834,433 (GRCm39) |
T672A |
probably benign |
Het |
| Ckmt1 |
T |
C |
2: 121,191,712 (GRCm39) |
|
probably null |
Het |
| Col25a1 |
A |
T |
3: 130,313,430 (GRCm39) |
E280V |
possibly damaging |
Het |
| Dnajc12 |
A |
G |
10: 63,233,087 (GRCm39) |
D76G |
probably damaging |
Het |
| Drd3 |
G |
T |
16: 43,643,164 (GRCm39) |
E467* |
probably null |
Het |
| Ecpas |
A |
G |
4: 58,844,191 (GRCm39) |
V525A |
probably damaging |
Het |
| Ehbp1l1 |
C |
A |
19: 5,769,204 (GRCm39) |
A700S |
possibly damaging |
Het |
| Gab1 |
T |
C |
8: 81,515,682 (GRCm39) |
D212G |
possibly damaging |
Het |
| Gm26996 |
A |
G |
6: 130,557,134 (GRCm39) |
|
noncoding transcript |
Het |
| Gm28113 |
A |
G |
15: 75,198,577 (GRCm39) |
|
noncoding transcript |
Het |
| Has3 |
T |
C |
8: 107,604,718 (GRCm39) |
F308S |
probably damaging |
Het |
| Ifit3b |
T |
A |
19: 34,588,860 (GRCm39) |
I12N |
probably benign |
Het |
| Ifna4 |
C |
A |
4: 88,760,519 (GRCm39) |
T141K |
probably benign |
Het |
| Ints3 |
A |
G |
3: 90,301,084 (GRCm39) |
S840P |
probably damaging |
Het |
| Itih4 |
T |
C |
14: 30,611,792 (GRCm39) |
V132A |
probably damaging |
Het |
| Itprid2 |
T |
A |
2: 79,493,101 (GRCm39) |
I1216N |
probably damaging |
Het |
| Kcnj10 |
A |
G |
1: 172,196,639 (GRCm39) |
Y51C |
probably damaging |
Het |
| Klk1b24 |
G |
A |
7: 43,839,820 (GRCm39) |
V60I |
probably damaging |
Het |
| Klra14-ps |
C |
A |
6: 130,134,626 (GRCm39) |
|
noncoding transcript |
Het |
| Krt6b |
A |
G |
15: 101,586,520 (GRCm39) |
I323T |
probably damaging |
Het |
| Lilra5 |
A |
C |
7: 4,240,957 (GRCm39) |
Q17P |
probably benign |
Het |
| Map3k4 |
T |
C |
17: 12,451,851 (GRCm39) |
N1479S |
possibly damaging |
Het |
| Mbd3l2 |
A |
T |
9: 18,356,256 (GRCm39) |
I194F |
probably damaging |
Het |
| Megf10 |
T |
C |
18: 57,420,864 (GRCm39) |
I834T |
probably benign |
Het |
| Mterf4 |
G |
A |
1: 93,229,471 (GRCm39) |
T251M |
probably damaging |
Het |
| Mtmr3 |
A |
T |
11: 4,457,634 (GRCm39) |
D170E |
probably damaging |
Het |
| Myom3 |
C |
T |
4: 135,534,586 (GRCm39) |
|
probably null |
Het |
| Nemp1 |
G |
A |
10: 127,530,462 (GRCm39) |
V305I |
probably benign |
Het |
| Nlrp1b |
G |
T |
11: 71,072,232 (GRCm39) |
T537K |
probably benign |
Het |
| Npdc1 |
G |
A |
2: 25,298,957 (GRCm39) |
D284N |
probably damaging |
Het |
| Or5b3 |
T |
A |
19: 13,388,469 (GRCm39) |
C179S |
probably damaging |
Het |
| Or6c206 |
A |
G |
10: 129,097,045 (GRCm39) |
T72A |
possibly damaging |
Het |
| Or8k28 |
A |
G |
2: 86,286,580 (GRCm39) |
F12L |
possibly damaging |
Het |
| Pias1 |
A |
G |
9: 62,827,771 (GRCm39) |
V212A |
probably damaging |
Het |
| Plscr1 |
T |
A |
9: 92,145,221 (GRCm39) |
V77D |
probably damaging |
Het |
| Plxna1 |
T |
C |
6: 89,299,798 (GRCm39) |
N1657S |
probably damaging |
Het |
| Ptprf |
A |
G |
4: 118,069,414 (GRCm39) |
V1551A |
possibly damaging |
Het |
| Ptprn2 |
C |
A |
12: 117,211,393 (GRCm39) |
Y857* |
probably null |
Het |
| Puf60 |
A |
T |
15: 75,944,183 (GRCm39) |
|
probably null |
Het |
| Rnf20 |
C |
T |
4: 49,654,579 (GRCm39) |
R879* |
probably null |
Het |
| Robo1 |
G |
A |
16: 72,768,931 (GRCm39) |
A499T |
probably damaging |
Het |
| Slc39a14 |
A |
G |
14: 70,551,048 (GRCm39) |
|
probably null |
Het |
| Smarcad1 |
A |
T |
6: 65,052,025 (GRCm39) |
H6L |
probably damaging |
Het |
| Smg5 |
A |
G |
3: 88,243,758 (GRCm39) |
S10G |
possibly damaging |
Het |
| Stk39 |
T |
A |
2: 68,093,647 (GRCm39) |
D488V |
probably damaging |
Het |
| Stx19 |
A |
G |
16: 62,642,495 (GRCm39) |
N104D |
probably benign |
Het |
| Tcstv1b |
A |
T |
13: 120,635,173 (GRCm39) |
S152C |
possibly damaging |
Het |
| Tmem222 |
T |
C |
4: 133,004,975 (GRCm39) |
M21V |
probably benign |
Het |
| Trim43b |
T |
A |
9: 88,971,538 (GRCm39) |
N205I |
possibly damaging |
Het |
| Ubr4 |
C |
A |
4: 139,209,890 (GRCm39) |
H5017N |
possibly damaging |
Het |
| Vmn2r93 |
A |
G |
17: 18,536,960 (GRCm39) |
T548A |
probably damaging |
Het |
| Vps8 |
G |
A |
16: 21,267,154 (GRCm39) |
|
probably null |
Het |
| Wasl |
A |
G |
6: 24,633,110 (GRCm39) |
V176A |
probably benign |
Het |
| Wbp2nl |
T |
A |
15: 82,190,255 (GRCm39) |
V61E |
probably damaging |
Het |
| Zfp959 |
T |
A |
17: 56,205,260 (GRCm39) |
|
probably null |
Het |
| Zmiz1 |
T |
C |
14: 25,644,098 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Lrrc7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00594:Lrrc7
|
APN |
3 |
157,892,647 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00644:Lrrc7
|
APN |
3 |
157,908,005 (GRCm39) |
nonsense |
probably null |
|
|
IGL00822:Lrrc7
|
APN |
3 |
157,891,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00927:Lrrc7
|
APN |
3 |
157,866,727 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00946:Lrrc7
|
APN |
3 |
157,866,993 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00948:Lrrc7
|
APN |
3 |
157,867,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01838:Lrrc7
|
APN |
3 |
157,891,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Lrrc7
|
APN |
3 |
157,946,080 (GRCm39) |
splice site |
probably benign |
|
|
IGL02514:Lrrc7
|
APN |
3 |
157,865,929 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02545:Lrrc7
|
APN |
3 |
157,891,011 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Lrrc7
|
APN |
3 |
157,866,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03129:Lrrc7
|
APN |
3 |
157,866,696 (GRCm39) |
missense |
probably benign |
0.02 |
|
N/A:Lrrc7
|
UTSW |
3 |
157,865,977 (GRCm39) |
missense |
probably benign |
|
|
R0021:Lrrc7
|
UTSW |
3 |
157,866,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0041:Lrrc7
|
UTSW |
3 |
157,869,897 (GRCm39) |
splice site |
probably benign |
|
|
R0255:Lrrc7
|
UTSW |
3 |
157,866,475 (GRCm39) |
nonsense |
probably null |
|
|
R0278:Lrrc7
|
UTSW |
3 |
157,885,432 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0409:Lrrc7
|
UTSW |
3 |
157,867,063 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0612:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0866:Lrrc7
|
UTSW |
3 |
157,869,903 (GRCm39) |
splice site |
probably benign |
|
|
R1077:Lrrc7
|
UTSW |
3 |
157,866,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1103:Lrrc7
|
UTSW |
3 |
157,854,343 (GRCm39) |
splice site |
probably benign |
|
|
R1157:Lrrc7
|
UTSW |
3 |
157,865,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1187:Lrrc7
|
UTSW |
3 |
157,866,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1301:Lrrc7
|
UTSW |
3 |
157,840,968 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1433:Lrrc7
|
UTSW |
3 |
157,882,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Lrrc7
|
UTSW |
3 |
157,892,681 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1595:Lrrc7
|
UTSW |
3 |
157,882,914 (GRCm39) |
nonsense |
probably null |
|
|
R1659:Lrrc7
|
UTSW |
3 |
157,867,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1693:Lrrc7
|
UTSW |
3 |
157,790,170 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1774:Lrrc7
|
UTSW |
3 |
157,865,929 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2273:Lrrc7
|
UTSW |
3 |
157,892,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2276:Lrrc7
|
UTSW |
3 |
157,885,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2302:Lrrc7
|
UTSW |
3 |
157,840,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2326:Lrrc7
|
UTSW |
3 |
157,876,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2371:Lrrc7
|
UTSW |
3 |
157,866,697 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2383:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R2679:Lrrc7
|
UTSW |
3 |
157,880,745 (GRCm39) |
nonsense |
probably null |
|
|
R2698:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2858:Lrrc7
|
UTSW |
3 |
157,867,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3758:Lrrc7
|
UTSW |
3 |
157,869,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3791:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R3805:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3806:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3807:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3892:Lrrc7
|
UTSW |
3 |
157,866,333 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3912:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3913:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Lrrc7
|
UTSW |
3 |
157,866,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4665:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4666:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4671:Lrrc7
|
UTSW |
3 |
157,908,132 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4688:Lrrc7
|
UTSW |
3 |
157,854,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4725:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4728:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4783:Lrrc7
|
UTSW |
3 |
157,832,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4867:Lrrc7
|
UTSW |
3 |
157,866,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4907:Lrrc7
|
UTSW |
3 |
157,866,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Lrrc7
|
UTSW |
3 |
157,887,217 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5107:Lrrc7
|
UTSW |
3 |
157,867,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5295:Lrrc7
|
UTSW |
3 |
157,876,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5348:Lrrc7
|
UTSW |
3 |
157,880,963 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5468:Lrrc7
|
UTSW |
3 |
158,024,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5778:Lrrc7
|
UTSW |
3 |
157,876,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6179:Lrrc7
|
UTSW |
3 |
158,059,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6312:Lrrc7
|
UTSW |
3 |
157,866,246 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6313:Lrrc7
|
UTSW |
3 |
157,866,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6366:Lrrc7
|
UTSW |
3 |
157,841,012 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6389:Lrrc7
|
UTSW |
3 |
157,891,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Lrrc7
|
UTSW |
3 |
157,840,940 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6956:Lrrc7
|
UTSW |
3 |
157,994,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6969:Lrrc7
|
UTSW |
3 |
157,862,550 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7073:Lrrc7
|
UTSW |
3 |
157,832,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7313:Lrrc7
|
UTSW |
3 |
157,866,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7365:Lrrc7
|
UTSW |
3 |
157,903,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7398:Lrrc7
|
UTSW |
3 |
157,997,595 (GRCm39) |
nonsense |
probably null |
|
|
R7403:Lrrc7
|
UTSW |
3 |
157,854,311 (GRCm39) |
nonsense |
probably null |
|
|
R7407:Lrrc7
|
UTSW |
3 |
157,840,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Lrrc7
|
UTSW |
3 |
157,903,778 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7453:Lrrc7
|
UTSW |
3 |
157,891,046 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Lrrc7
|
UTSW |
3 |
157,892,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7807:Lrrc7
|
UTSW |
3 |
157,866,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Lrrc7
|
UTSW |
3 |
158,059,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Lrrc7
|
UTSW |
3 |
157,915,387 (GRCm39) |
missense |
probably benign |
|
|
R8367:Lrrc7
|
UTSW |
3 |
157,908,007 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8867:Lrrc7
|
UTSW |
3 |
157,867,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8880:Lrrc7
|
UTSW |
3 |
157,867,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8941:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R8958:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9068:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9069:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9180:Lrrc7
|
UTSW |
3 |
157,867,011 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9193:Lrrc7
|
UTSW |
3 |
158,059,011 (GRCm39) |
nonsense |
probably null |
|
|
R9309:Lrrc7
|
UTSW |
3 |
157,915,361 (GRCm39) |
nonsense |
probably null |
|
|
R9418:Lrrc7
|
UTSW |
3 |
157,908,023 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9474:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9515:Lrrc7
|
UTSW |
3 |
157,867,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9635:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9639:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9682:Lrrc7
|
UTSW |
3 |
157,882,954 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9731:Lrrc7
|
UTSW |
3 |
157,880,888 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCTCTGAAAATGAGGATGAACC -3'
(R):5'- AGTGAGTCTAGCCAAACTGTG -3'
Sequencing Primer
(F):5'- CTAGTAGAGGATGCAAAATGGTTTAG -3'
(R):5'- CCAAACTGTGGCCTAACTAGTGAG -3'
|
| Posted On |
2016-07-08 |
Incidental Mutation