Mutagenetix > Incidental Mutation

Incidental Mutation 'R5223:Pcnt'

402444

Institutional Source

Beutler Lab

Gene Symbol

Pcnt

Ensembl Gene

ENSMUSG00000001151

Gene Name

pericentrin (kendrin)

Synonyms

m239Asp, m275Asp, Pcnt2

MMRRC Submission

042796-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5223 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

76351263-76442786 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 76380272 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Aspartic acid at position 2261 (N2261D)

Ref Sequence

ENSEMBL: ENSMUSP00000001179 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000001179] [ENSMUST00000217838]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000001179
AA Change: N2261D

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000001179
Gene: ENSMUSG00000001151
AA Change: N2261D

Domain	Start	End	E-Value	Type
internal_repeat_1	7	78	2.47e-5	PROSPERO
low complexity region	104	114	N/A	INTRINSIC
coiled coil region	131	229	N/A	INTRINSIC
internal_repeat_3	241	259	6.69e-5	PROSPERO
low complexity region	313	325	N/A	INTRINSIC
internal_repeat_3	391	409	6.69e-5	PROSPERO
low complexity region	456	467	N/A	INTRINSIC
coiled coil region	468	520	N/A	INTRINSIC
coiled coil region	554	581	N/A	INTRINSIC
low complexity region	652	666	N/A	INTRINSIC
coiled coil region	727	787	N/A	INTRINSIC
coiled coil region	871	916	N/A	INTRINSIC
low complexity region	931	942	N/A	INTRINSIC
low complexity region	969	985	N/A	INTRINSIC
coiled coil region	1055	1383	N/A	INTRINSIC
coiled coil region	1429	1481	N/A	INTRINSIC
coiled coil region	1529	1567	N/A	INTRINSIC
low complexity region	1614	1624	N/A	INTRINSIC
internal_repeat_2	1916	1964	2.47e-5	PROSPERO
coiled coil region	2158	2178	N/A	INTRINSIC
coiled coil region	2211	2279	N/A	INTRINSIC
coiled coil region	2300	2421	N/A	INTRINSIC
coiled coil region	2447	2526	N/A	INTRINSIC
Pfam:PACT_coil_coil	2718	2797	5.8e-29	PFAM
internal_repeat_1	2820	2885	2.47e-5	PROSPERO
internal_repeat_2	2844	2891	2.47e-5	PROSPERO

Predicted Effect

probably damaging
Transcript: ENSMUST00000217838
AA Change: N2261D

PolyPhen 2 Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000220395

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.6%
20x: 93.2%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a gene trapped allele display mitotic spindle misorientation, microcephaly, craniofacial developmental anomalies, such as cleft palate and eye defects, variable structural kidney and cardiovascular defects, and altered hemodynamics leading to heart failure and prenatal lethality. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aatk	C	T	11: 120,013,452 (GRCm38)	V273M	possibly damaging	Het
Acin1	CCGC	CC	14: 54,642,941 (GRCm38)		probably null	Het
Acvr1b	T	A	15: 101,193,976 (GRCm38)	C46S	probably damaging	Het
Ahi1	A	T	10: 20,970,919 (GRCm38)	H416L	possibly damaging	Het
Aspm	T	A	1: 139,478,334 (GRCm38)	L1653Q	probably damaging	Het
Cacna1a	G	A	8: 84,587,195 (GRCm38)	V1533M	possibly damaging	Het
Ccdc33	C	T	9: 58,032,984 (GRCm38)	E502K	possibly damaging	Het
Ctnnd1	C	T	2: 84,616,789 (GRCm38)	V371M	probably damaging	Het
Cyp2a12	A	T	7: 27,036,463 (GRCm38)		probably null	Het
Ep400	A	G	5: 110,668,630 (GRCm38)	V2675A	probably damaging	Het
Foxh1	T	A	15: 76,668,729 (GRCm38)		probably null	Het
Gad1-ps	G	A	10: 99,445,147 (GRCm38)		noncoding transcript	Het
Gm10093	A	G	17: 78,492,438 (GRCm38)	E286G	probably benign	Het
Gm13078	T	A	4: 143,728,021 (GRCm38)	S296R	probably benign	Het
Gpnmb	C	T	6: 49,056,205 (GRCm38)	T539M	probably benign	Het
Hspa9	A	G	18: 34,952,671 (GRCm38)		probably null	Het
Hspg2	T	C	4: 137,543,914 (GRCm38)	L2454P	probably damaging	Het
Ift140	T	A	17: 25,035,812 (GRCm38)	I422N	probably benign	Het
Igkv6-32	T	C	6: 70,074,223 (GRCm38)	S50G	probably benign	Het
Il23r	T	A	6: 67,486,170 (GRCm38)	Y113F	probably benign	Het
Kcnt1	A	G	2: 25,903,422 (GRCm38)	D636G	probably benign	Het
Klhl41	G	A	2: 69,679,827 (GRCm38)	W569*	probably null	Het
Klra4	T	A	6: 130,062,147 (GRCm38)	D94V	probably damaging	Het
Lca5	T	A	9: 83,398,613 (GRCm38)	H378L	probably benign	Het
Lhx8	T	A	3: 154,321,644 (GRCm38)	T254S	probably damaging	Het
Lrch3	C	T	16: 32,914,397 (GRCm38)	R86W	probably damaging	Het
Lrp2	T	A	2: 69,524,053 (GRCm38)	N477I	probably damaging	Het
Man2a1	T	A	17: 64,712,271 (GRCm38)	I710K	probably benign	Het
Ncor1	A	T	11: 62,339,000 (GRCm38)	Y881N	probably damaging	Het
Nhsl1	T	A	10: 18,526,326 (GRCm38)	V1100E	probably damaging	Het
Olfr1208	T	C	2: 88,897,334 (GRCm38)	T88A	probably benign	Het
Olfr486	A	G	7: 108,172,708 (GRCm38)	V12A	probably benign	Het
Olfr855	T	C	9: 19,585,026 (GRCm38)	V163A	probably benign	Het
Oprk1	T	C	1: 5,589,296 (GRCm38)	V83A	probably benign	Het
Pacs1	C	T	19: 5,145,141 (GRCm38)	V472I	probably benign	Het
Pard3b	T	C	1: 62,344,113 (GRCm38)	Y789H	probably damaging	Het
Pcdha2	T	C	18: 36,940,791 (GRCm38)	Y492H	probably damaging	Het
Pex5l	A	T	3: 32,958,796 (GRCm38)	S15T	probably damaging	Het
Plekhg4	A	G	8: 105,378,949 (GRCm38)	N682S	probably benign	Het
Poc5	A	T	13: 96,402,955 (GRCm38)	M335L	probably benign	Het
Polr1a	C	T	6: 71,967,907 (GRCm38)	R1316W	possibly damaging	Het
Pp2d1	T	C	17: 53,507,845 (GRCm38)	H617R	probably benign	Het
Prpsap1	T	C	11: 116,488,148 (GRCm38)	K65E	probably benign	Het
Ptgfrn	T	C	3: 101,045,593 (GRCm38)	E775G	probably benign	Het
Ptprc	T	A	1: 138,117,862 (GRCm38)	I87F	probably benign	Het
Rbbp8	C	A	18: 11,721,690 (GRCm38)	A324E	probably benign	Het
Rfx6	G	T	10: 51,677,996 (GRCm38)	G63*	probably null	Het
Rpl37a	T	C	1: 72,712,149 (GRCm38)	M47T	probably benign	Het
Samm50	T	G	15: 84,200,630 (GRCm38)	N187K	probably benign	Het
Skiv2l	A	G	17: 34,845,166 (GRCm38)		probably null	Het
Slamf9	T	C	1: 172,476,232 (GRCm38)	I48T	possibly damaging	Het
Slc2a12	A	G	10: 22,702,032 (GRCm38)	K576E	probably damaging	Het
Slc4a10	G	A	2: 62,253,366 (GRCm38)	G388S	probably damaging	Het
Smtn	G	T	11: 3,529,530 (GRCm38)	N512K	probably benign	Het
Sntb1	C	G	15: 55,642,795 (GRCm38)	G461R	probably damaging	Het
Sspo	A	G	6: 48,478,324 (GRCm38)	Y3040C	probably damaging	Het
Stat1	T	A	1: 52,144,242 (GRCm38)	V389E	probably damaging	Het
Sult5a1	A	T	8: 123,145,422 (GRCm38)	M227K	probably damaging	Het
Thsd4	T	C	9: 60,057,042 (GRCm38)	D389G	probably damaging	Het
Tnxb	T	C	17: 34,704,078 (GRCm38)	V2545A	possibly damaging	Het
Tpo	T	A	12: 30,092,590 (GRCm38)	I712F	probably damaging	Het
Trim62	T	C	4: 128,909,411 (GRCm38)	V418A	probably damaging	Het
Uqcrc1	C	A	9: 108,942,156 (GRCm38)	H95N	probably damaging	Het
Vmn2r114	ATTT	ATT	17: 23,290,932 (GRCm38)		probably null	Het
Vmn2r66	T	C	7: 85,007,885 (GRCm38)	D104G	probably benign	Het
Wdr26	T	C	1: 181,187,686 (GRCm38)	I371V	probably benign	Het
Wdr78	T	A	4: 103,049,403 (GRCm38)	S738C	possibly damaging	Het
Zfp273	T	G	13: 67,826,179 (GRCm38)	C475W	probably damaging	Het
Zfp738	G	T	13: 67,673,063 (GRCm38)	T55K	probably damaging	Het
Zmym2	A	G	14: 56,946,514 (GRCm38)	I978V	probably benign	Het

Other mutations in Pcnt

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01075:Pcnt	APN	10	76,422,904 (GRCm38)	nonsense	probably null
IGL01307:Pcnt	APN	10	76,411,588 (GRCm38)	missense	probably damaging	1.00
IGL01549:Pcnt	APN	10	76,367,486 (GRCm38)	splice site	probably null
IGL01576:Pcnt	APN	10	76,368,822 (GRCm38)	missense	probably damaging	0.99
IGL01611:Pcnt	APN	10	76,436,424 (GRCm38)	critical splice donor site	probably null
IGL01630:Pcnt	APN	10	76,420,246 (GRCm38)	missense	probably damaging	0.99
IGL01647:Pcnt	APN	10	76,370,001 (GRCm38)	nonsense	probably null
IGL01689:Pcnt	APN	10	76,411,653 (GRCm38)	missense	probably damaging	1.00
IGL01690:Pcnt	APN	10	76,392,775 (GRCm38)	missense	probably damaging	1.00
IGL01723:Pcnt	APN	10	76,418,499 (GRCm38)	missense	possibly damaging	0.63
IGL01920:Pcnt	APN	10	76,404,528 (GRCm38)	missense	probably damaging	1.00
IGL01958:Pcnt	APN	10	76,433,679 (GRCm38)	missense	probably damaging	0.96
IGL02210:Pcnt	APN	10	76,389,219 (GRCm38)	missense	possibly damaging	0.95
IGL02225:Pcnt	APN	10	76,389,474 (GRCm38)	missense	probably benign	0.00
IGL02228:Pcnt	APN	10	76,389,474 (GRCm38)	missense	probably benign	0.00
IGL02237:Pcnt	APN	10	76,352,984 (GRCm38)	missense	probably damaging	1.00
IGL02279:Pcnt	APN	10	76,403,765 (GRCm38)	missense	probably damaging	1.00
IGL02303:Pcnt	APN	10	76,442,559 (GRCm38)	splice site	probably benign
IGL02355:Pcnt	APN	10	76,375,162 (GRCm38)	nonsense	probably null
IGL02362:Pcnt	APN	10	76,375,162 (GRCm38)	nonsense	probably null
IGL02428:Pcnt	APN	10	76,429,256 (GRCm38)	missense	probably damaging	0.99
IGL02536:Pcnt	APN	10	76,380,229 (GRCm38)	missense	possibly damaging	0.68
IGL02715:Pcnt	APN	10	76,368,722 (GRCm38)	splice site	probably benign
IGL02800:Pcnt	APN	10	76,412,583 (GRCm38)	nonsense	probably null
IGL03395:Pcnt	APN	10	76,436,491 (GRCm38)	missense	possibly damaging	0.95
IGL02799:Pcnt	UTSW	10	76,412,583 (GRCm38)	nonsense	probably null
PIT4520001:Pcnt	UTSW	10	76,420,235 (GRCm38)	missense	probably damaging	0.99
R0049:Pcnt	UTSW	10	76,369,821 (GRCm38)	unclassified	probably benign
R0049:Pcnt	UTSW	10	76,369,821 (GRCm38)	unclassified	probably benign
R0109:Pcnt	UTSW	10	76,389,196 (GRCm38)	missense	probably benign	0.00
R0117:Pcnt	UTSW	10	76,408,727 (GRCm38)	nonsense	probably null
R0254:Pcnt	UTSW	10	76,392,580 (GRCm38)	missense	probably benign	0.10
R0392:Pcnt	UTSW	10	76,384,826 (GRCm38)	missense	probably benign
R0511:Pcnt	UTSW	10	76,404,595 (GRCm38)	missense	possibly damaging	0.66
R0570:Pcnt	UTSW	10	76,412,107 (GRCm38)	missense	probably damaging	1.00
R0614:Pcnt	UTSW	10	76,420,316 (GRCm38)	missense	probably damaging	1.00
R0635:Pcnt	UTSW	10	76,404,585 (GRCm38)	missense	probably damaging	1.00
R0707:Pcnt	UTSW	10	76,420,541 (GRCm38)	missense	probably damaging	1.00
R0749:Pcnt	UTSW	10	76,381,364 (GRCm38)	missense	probably damaging	1.00
R0969:Pcnt	UTSW	10	76,427,951 (GRCm38)	missense	probably damaging	1.00
R1172:Pcnt	UTSW	10	76,393,044 (GRCm38)	splice site	probably null
R1174:Pcnt	UTSW	10	76,393,044 (GRCm38)	splice site	probably null
R1175:Pcnt	UTSW	10	76,393,044 (GRCm38)	splice site	probably null
R1512:Pcnt	UTSW	10	76,404,662 (GRCm38)	splice site	probably null
R1542:Pcnt	UTSW	10	76,401,386 (GRCm38)	missense	probably benign	0.02
R1542:Pcnt	UTSW	10	76,389,387 (GRCm38)	missense	probably benign	0.08
R1558:Pcnt	UTSW	10	76,422,922 (GRCm38)	missense	possibly damaging	0.53
R1562:Pcnt	UTSW	10	76,367,330 (GRCm38)	missense	probably benign	0.02
R1762:Pcnt	UTSW	10	76,355,137 (GRCm38)	critical splice acceptor site	probably null
R1779:Pcnt	UTSW	10	76,408,796 (GRCm38)	missense	probably damaging	0.99
R1869:Pcnt	UTSW	10	76,379,906 (GRCm38)	missense	probably null	0.94
R1911:Pcnt	UTSW	10	76,368,816 (GRCm38)	missense	possibly damaging	0.94
R1985:Pcnt	UTSW	10	76,380,337 (GRCm38)	missense	possibly damaging	0.95
R1995:Pcnt	UTSW	10	76,392,799 (GRCm38)	nonsense	probably null
R2073:Pcnt	UTSW	10	76,380,380 (GRCm38)	missense	possibly damaging	0.92
R2111:Pcnt	UTSW	10	76,420,526 (GRCm38)	missense	probably damaging	0.99
R2112:Pcnt	UTSW	10	76,420,526 (GRCm38)	missense	probably damaging	0.99
R2309:Pcnt	UTSW	10	76,442,626 (GRCm38)	start gained	probably benign
R2902:Pcnt	UTSW	10	76,375,230 (GRCm38)	missense	probably damaging	0.98
R3623:Pcnt	UTSW	10	76,433,750 (GRCm38)	missense	probably benign	0.23
R4088:Pcnt	UTSW	10	76,428,014 (GRCm38)	missense	probably damaging	1.00
R4300:Pcnt	UTSW	10	76,367,391 (GRCm38)	missense	probably benign	0.40
R4402:Pcnt	UTSW	10	76,392,393 (GRCm38)	missense	probably benign	0.00
R4407:Pcnt	UTSW	10	76,374,870 (GRCm38)	missense	possibly damaging	0.90
R4483:Pcnt	UTSW	10	76,401,483 (GRCm38)	missense	probably damaging	1.00
R4647:Pcnt	UTSW	10	76,354,213 (GRCm38)	missense	probably benign	0.01
R4734:Pcnt	UTSW	10	76,437,206 (GRCm38)	missense	probably benign	0.25
R4747:Pcnt	UTSW	10	76,436,465 (GRCm38)	missense	possibly damaging	0.91
R4782:Pcnt	UTSW	10	76,409,577 (GRCm38)	missense	possibly damaging	0.62
R4795:Pcnt	UTSW	10	76,370,024 (GRCm38)	missense	probably benign	0.21
R4831:Pcnt	UTSW	10	76,412,501 (GRCm38)	missense	probably damaging	0.96
R4873:Pcnt	UTSW	10	76,369,854 (GRCm38)	missense	probably benign	0.03
R4875:Pcnt	UTSW	10	76,369,854 (GRCm38)	missense	probably benign	0.03
R4946:Pcnt	UTSW	10	76,356,185 (GRCm38)	missense	probably damaging	1.00
R5032:Pcnt	UTSW	10	76,355,077 (GRCm38)	missense	probably benign	0.00
R5033:Pcnt	UTSW	10	76,399,945 (GRCm38)	missense	possibly damaging	0.95
R5106:Pcnt	UTSW	10	76,401,444 (GRCm38)	missense	probably damaging	1.00
R5118:Pcnt	UTSW	10	76,412,168 (GRCm38)	missense	probably damaging	0.98
R5167:Pcnt	UTSW	10	76,420,424 (GRCm38)	missense	probably damaging	0.97
R5199:Pcnt	UTSW	10	76,418,544 (GRCm38)	missense	probably benign	0.09
R5241:Pcnt	UTSW	10	76,433,617 (GRCm38)	missense	probably benign	0.26
R5308:Pcnt	UTSW	10	76,356,325 (GRCm38)	nonsense	probably null
R5328:Pcnt	UTSW	10	76,411,719 (GRCm38)	missense	probably damaging	1.00
R5454:Pcnt	UTSW	10	76,389,547 (GRCm38)	splice site	probably null
R5543:Pcnt	UTSW	10	76,412,052 (GRCm38)	missense	probably benign	0.01
R5588:Pcnt	UTSW	10	76,442,611 (GRCm38)	missense	possibly damaging	0.74
R5647:Pcnt	UTSW	10	76,385,841 (GRCm38)	missense	probably benign	0.17
R5668:Pcnt	UTSW	10	76,409,500 (GRCm38)	missense	probably benign	0.16
R5712:Pcnt	UTSW	10	76,429,271 (GRCm38)	missense	probably damaging	0.96
R5714:Pcnt	UTSW	10	76,420,491 (GRCm38)	missense	probably damaging	1.00
R5797:Pcnt	UTSW	10	76,392,756 (GRCm38)	missense	probably benign	0.00
R5946:Pcnt	UTSW	10	76,382,063 (GRCm38)	missense	possibly damaging	0.91
R5955:Pcnt	UTSW	10	76,411,622 (GRCm38)	missense	possibly damaging	0.45
R6024:Pcnt	UTSW	10	76,420,037 (GRCm38)	missense	possibly damaging	0.87
R6267:Pcnt	UTSW	10	76,385,798 (GRCm38)	missense	probably benign	0.02
R6485:Pcnt	UTSW	10	76,389,330 (GRCm38)	nonsense	probably null
R6605:Pcnt	UTSW	10	76,429,198 (GRCm38)	critical splice donor site	probably null
R6877:Pcnt	UTSW	10	76,434,017 (GRCm38)	missense	possibly damaging	0.94
R6882:Pcnt	UTSW	10	76,427,828 (GRCm38)	missense	probably benign	0.00
R6919:Pcnt	UTSW	10	76,385,798 (GRCm38)	missense	probably benign	0.02
R7025:Pcnt	UTSW	10	76,403,835 (GRCm38)	missense	probably damaging	1.00
R7098:Pcnt	UTSW	10	76,384,839 (GRCm38)	missense	probably benign
R7109:Pcnt	UTSW	10	76,369,904 (GRCm38)	missense	probably damaging	1.00
R7121:Pcnt	UTSW	10	76,427,927 (GRCm38)	missense	possibly damaging	0.73
R7143:Pcnt	UTSW	10	76,389,060 (GRCm38)	missense	possibly damaging	0.47
R7152:Pcnt	UTSW	10	76,411,360 (GRCm38)	splice site	probably null
R7213:Pcnt	UTSW	10	76,408,904 (GRCm38)	missense	probably damaging	1.00
R7368:Pcnt	UTSW	10	76,400,001 (GRCm38)	missense	probably benign
R7453:Pcnt	UTSW	10	76,389,450 (GRCm38)	missense	probably benign
R7486:Pcnt	UTSW	10	76,418,437 (GRCm38)	missense	probably benign
R7486:Pcnt	UTSW	10	76,418,436 (GRCm38)	missense	probably benign	0.03
R7538:Pcnt	UTSW	10	76,399,939 (GRCm38)	missense	probably benign
R7575:Pcnt	UTSW	10	76,389,252 (GRCm38)	missense	probably benign	0.32
R7662:Pcnt	UTSW	10	76,387,522 (GRCm38)	missense	probably benign	0.27
R7685:Pcnt	UTSW	10	76,422,808 (GRCm38)	missense	probably benign	0.14
R7764:Pcnt	UTSW	10	76,354,248 (GRCm38)	missense	probably benign	0.33
R7802:Pcnt	UTSW	10	76,375,303 (GRCm38)	splice site	probably null
R8432:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8439:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8493:Pcnt	UTSW	10	76,403,623 (GRCm38)	critical splice donor site	probably null
R8530:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8535:Pcnt	UTSW	10	76,420,205 (GRCm38)	missense	probably damaging	1.00
R8830:Pcnt	UTSW	10	76,382,174 (GRCm38)	missense	probably benign	0.03
R8878:Pcnt	UTSW	10	76,408,841 (GRCm38)	missense	probably damaging	1.00
R8911:Pcnt	UTSW	10	76,387,525 (GRCm38)	missense	probably damaging	0.98
R8988:Pcnt	UTSW	10	76,409,573 (GRCm38)	nonsense	probably null
R9084:Pcnt	UTSW	10	76,399,992 (GRCm38)	missense	probably benign	0.09
R9169:Pcnt	UTSW	10	76,385,738 (GRCm38)	missense	possibly damaging	0.95
R9372:Pcnt	UTSW	10	76,423,126 (GRCm38)	missense	probably damaging	1.00
R9411:Pcnt	UTSW	10	76,423,062 (GRCm38)	missense	probably damaging	0.96
R9448:Pcnt	UTSW	10	76,420,526 (GRCm38)	missense	probably damaging	0.99
R9459:Pcnt	UTSW	10	76,392,738 (GRCm38)	missense	probably damaging	1.00
R9479:Pcnt	UTSW	10	76,382,129 (GRCm38)	missense	probably benign	0.00
R9503:Pcnt	UTSW	10	76,428,048 (GRCm38)	missense	possibly damaging	0.59
R9561:Pcnt	UTSW	10	76,381,294 (GRCm38)	nonsense	probably null
R9618:Pcnt	UTSW	10	76,352,960 (GRCm38)	missense	probably damaging	1.00
R9648:Pcnt	UTSW	10	76,354,255 (GRCm38)	missense	probably benign	0.32
R9733:Pcnt	UTSW	10	76,401,480 (GRCm38)	missense	probably benign	0.01
Z1176:Pcnt	UTSW	10	76,382,157 (GRCm38)	nonsense	probably null
Z1177:Pcnt	UTSW	10	76,399,968 (GRCm38)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- AGAAAGGCAGTCACCTCCAG -3'
(R):5'- AGGGATAACGTGCTGTCTACC -3'

Sequencing Primer
(F):5'- TCTGCAGGTACCGCAGTTG -3'
(R):5'- AACGTGCTGTCTACCGTTTTAATTC -3'

Posted On

2016-07-22