Incidental Mutation 'R0415:Cd109'
| ID |
40251 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cd109
|
| Ensembl Gene |
ENSMUSG00000046186 |
| Gene Name |
CD109 antigen |
| Synonyms |
Gov platelet alloantigens, 9930012E15Rik |
| MMRRC Submission |
038617-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0415 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
78615546-78716253 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 78712615 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 1380
(S1380T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091330
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093812]
|
| AlphaFold |
Q8R422 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093812
AA Change: S1380T
PolyPhen 2
Score 0.129 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000091330
Gene: ENSMUSG00000046186
AA Change: S1380T
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
129 |
220 |
1.5e-16 |
PFAM |
|
A2M_N_2
|
470 |
601 |
8.89e-32 |
SMART |
|
A2M
|
695 |
786 |
2.07e-32 |
SMART |
|
Pfam:Thiol-ester_cl
|
912 |
941 |
2.6e-20 |
PFAM |
|
Pfam:A2M_comp
|
961 |
1197 |
1.9e-65 |
PFAM |
|
low complexity region
|
1265 |
1275 |
N/A |
INTRINSIC |
|
A2M_recep
|
1311 |
1395 |
2.06e-27 |
SMART |
|
low complexity region
|
1422 |
1437 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0590 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.6%
|
| Validation Efficiency |
97% (99/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
PHENOTYPE: Mice homozygous for a null mutation display epidermal hyperplasia and thickening, sebaceous gland hyperplasia and transient impairment of hair growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427G23Rik |
A |
T |
5: 23,831,050 (GRCm38) |
|
noncoding transcript |
Het |
| Acox2 |
A |
G |
14: 8,243,835 (GRCm38) |
|
probably benign |
Het |
| Adgb |
T |
C |
10: 10,431,067 (GRCm38) |
|
probably null |
Het |
| Adgra3 |
C |
A |
5: 49,961,757 (GRCm38) |
|
probably benign |
Het |
| Adgre4 |
G |
A |
17: 55,852,288 (GRCm38) |
V658I |
probably benign |
Het |
| Ahnak |
A |
G |
19: 9,012,871 (GRCm38) |
|
probably benign |
Het |
| Anapc2 |
A |
G |
2: 25,278,325 (GRCm38) |
T159A |
probably damaging |
Het |
| Arfgef3 |
A |
G |
10: 18,613,127 (GRCm38) |
|
probably benign |
Het |
| Atf7ip |
C |
T |
6: 136,560,012 (GRCm38) |
S81L |
possibly damaging |
Het |
| Cacna1i |
A |
G |
15: 80,368,830 (GRCm38) |
|
probably benign |
Het |
| Camk1 |
A |
T |
6: 113,341,891 (GRCm38) |
Y20* |
probably null |
Het |
| Ccdc40 |
T |
C |
11: 119,232,118 (GRCm38) |
Y249H |
possibly damaging |
Het |
| Cfap57 |
A |
T |
4: 118,569,431 (GRCm38) |
L1107Q |
possibly damaging |
Het |
| Col6a4 |
C |
T |
9: 106,075,080 (GRCm38) |
V540I |
probably damaging |
Het |
| Cst9 |
T |
A |
2: 148,838,442 (GRCm38) |
|
probably benign |
Het |
| Cul5 |
C |
T |
9: 53,667,070 (GRCm38) |
V73I |
probably benign |
Het |
| Cxcl16 |
T |
A |
11: 70,458,748 (GRCm38) |
K84* |
probably null |
Het |
| Cyp2c29 |
T |
C |
19: 39,329,095 (GRCm38) |
|
probably benign |
Het |
| D6Ertd527e |
C |
G |
6: 87,111,524 (GRCm38) |
T223S |
unknown |
Het |
| Dip2c |
C |
T |
13: 9,568,289 (GRCm38) |
|
probably benign |
Het |
| Dis3 |
A |
T |
14: 99,087,456 (GRCm38) |
I513N |
probably damaging |
Het |
| Dnajc16 |
A |
T |
4: 141,789,048 (GRCm38) |
L3* |
probably null |
Het |
| Dopey1 |
T |
A |
9: 86,506,502 (GRCm38) |
L480M |
probably damaging |
Het |
| Eml6 |
A |
G |
11: 29,749,392 (GRCm38) |
V1787A |
possibly damaging |
Het |
| Etnk1 |
A |
G |
6: 143,180,774 (GRCm38) |
N115S |
probably damaging |
Het |
| Fryl |
T |
C |
5: 73,098,414 (GRCm38) |
Y758C |
probably damaging |
Het |
| Gbp4 |
G |
A |
5: 105,121,106 (GRCm38) |
R394C |
possibly damaging |
Het |
| Ggnbp2 |
A |
C |
11: 84,833,225 (GRCm38) |
|
probably benign |
Het |
| Gm7137 |
A |
G |
10: 77,788,173 (GRCm38) |
|
probably benign |
Het |
| Gstm2 |
T |
A |
3: 107,984,006 (GRCm38) |
Q132L |
probably benign |
Het |
| Habp2 |
T |
C |
19: 56,317,717 (GRCm38) |
|
probably benign |
Het |
| Hectd2 |
T |
C |
19: 36,584,884 (GRCm38) |
|
probably benign |
Het |
| Htr6 |
A |
G |
4: 139,062,081 (GRCm38) |
I291T |
possibly damaging |
Het |
| Ighg2c |
T |
C |
12: 113,287,910 (GRCm38) |
D199G |
unknown |
Het |
| Itih2 |
A |
G |
2: 10,105,615 (GRCm38) |
|
probably benign |
Het |
| Kcnab2 |
A |
G |
4: 152,395,136 (GRCm38) |
F248S |
probably benign |
Het |
| Kcnc4 |
T |
C |
3: 107,445,433 (GRCm38) |
K610E |
probably damaging |
Het |
| Kcnk16 |
T |
A |
14: 20,262,975 (GRCm38) |
|
probably null |
Het |
| Kndc1 |
C |
T |
7: 139,930,124 (GRCm38) |
T1293I |
probably damaging |
Het |
| Lcp1 |
A |
T |
14: 75,227,006 (GRCm38) |
I556F |
possibly damaging |
Het |
| Lrrc8d |
T |
C |
5: 105,811,865 (GRCm38) |
L47P |
probably damaging |
Het |
| Lyst |
T |
C |
13: 13,711,610 (GRCm38) |
|
probably benign |
Het |
| Macrod2 |
G |
A |
2: 142,210,145 (GRCm38) |
|
probably null |
Het |
| Micalcl |
C |
T |
7: 112,381,028 (GRCm38) |
R70C |
probably damaging |
Het |
| Mllt3 |
ACTGCTGCTGCTGCTGCTGCT |
ACTGCTGCTGCTGCTGCT |
4: 87,841,339 (GRCm38) |
|
probably benign |
Het |
| Msh3 |
A |
G |
13: 92,346,786 (GRCm38) |
V283A |
possibly damaging |
Het |
| Nup205 |
T |
C |
6: 35,214,634 (GRCm38) |
|
probably benign |
Het |
| Nxpe2 |
T |
C |
9: 48,326,614 (GRCm38) |
T114A |
probably damaging |
Het |
| Olfr1023 |
A |
T |
2: 85,887,438 (GRCm38) |
I213F |
possibly damaging |
Het |
| Olfr1034 |
A |
T |
2: 86,047,055 (GRCm38) |
H191L |
probably benign |
Het |
| Olfr229 |
A |
G |
9: 39,909,983 (GRCm38) |
Y60C |
probably damaging |
Het |
| Olfr78 |
C |
T |
7: 102,742,087 (GRCm38) |
M305I |
probably benign |
Het |
| Olfr893 |
A |
T |
9: 38,209,973 (GRCm38) |
M305L |
probably benign |
Het |
| Pard3 |
G |
A |
8: 127,610,566 (GRCm38) |
G1221D |
probably damaging |
Het |
| Pax5 |
G |
A |
4: 44,691,886 (GRCm38) |
A120V |
probably damaging |
Het |
| Pcsk6 |
C |
T |
7: 66,033,874 (GRCm38) |
R746C |
probably damaging |
Het |
| Pif1 |
G |
A |
9: 65,588,051 (GRCm38) |
C81Y |
probably benign |
Het |
| Plcb1 |
A |
G |
2: 135,337,499 (GRCm38) |
Y609C |
probably damaging |
Het |
| Plcd4 |
C |
A |
1: 74,552,097 (GRCm38) |
S217Y |
probably damaging |
Het |
| Plxna1 |
G |
A |
6: 89,357,336 (GRCm38) |
H104Y |
probably benign |
Het |
| Polr2k |
A |
G |
15: 36,175,456 (GRCm38) |
Y45C |
probably damaging |
Het |
| Pqlc3 |
C |
A |
12: 16,997,710 (GRCm38) |
|
probably benign |
Het |
| Prex1 |
A |
G |
2: 166,586,699 (GRCm38) |
|
probably benign |
Het |
| Pth2r |
A |
G |
1: 65,388,439 (GRCm38) |
M424V |
probably benign |
Het |
| Pygm |
A |
G |
19: 6,391,366 (GRCm38) |
R464G |
probably benign |
Het |
| Rad51c |
A |
G |
11: 87,397,655 (GRCm38) |
L234P |
probably damaging |
Het |
| Rnf145 |
A |
G |
11: 44,525,138 (GRCm38) |
Y60C |
probably damaging |
Het |
| Rnf167 |
T |
C |
11: 70,649,699 (GRCm38) |
I135T |
probably damaging |
Het |
| Rnf213 |
A |
T |
11: 119,414,469 (GRCm38) |
I509F |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,869,156 (GRCm38) |
S213G |
probably damaging |
Het |
| Selenbp1 |
T |
C |
3: 94,936,913 (GRCm38) |
V27A |
possibly damaging |
Het |
| Selenof |
T |
G |
3: 144,577,692 (GRCm38) |
L14R |
probably damaging |
Het |
| Sfswap |
A |
T |
5: 129,504,126 (GRCm38) |
D121V |
probably damaging |
Het |
| Slc25a34 |
C |
A |
4: 141,620,469 (GRCm38) |
M300I |
possibly damaging |
Het |
| Slc34a3 |
T |
G |
2: 25,229,110 (GRCm38) |
T583P |
probably benign |
Het |
| Smg1 |
C |
A |
7: 118,182,468 (GRCm38) |
A1199S |
probably benign |
Het |
| Spint1 |
A |
G |
2: 119,245,615 (GRCm38) |
T231A |
probably damaging |
Het |
| Sptbn1 |
A |
C |
11: 30,149,576 (GRCm38) |
N229K |
probably damaging |
Het |
| Sult2b1 |
A |
G |
7: 45,730,092 (GRCm38) |
|
probably benign |
Het |
| Tas2r123 |
A |
T |
6: 132,847,838 (GRCm38) |
M233L |
probably damaging |
Het |
| Tbcel |
C |
A |
9: 42,444,500 (GRCm38) |
C139F |
probably benign |
Het |
| Thbs2 |
A |
C |
17: 14,679,973 (GRCm38) |
S573A |
probably benign |
Het |
| Tmem132c |
A |
G |
5: 127,563,705 (GRCm38) |
E980G |
probably damaging |
Het |
| Tmem247 |
G |
T |
17: 86,922,322 (GRCm38) |
C197F |
probably damaging |
Het |
| Tmem251 |
T |
A |
12: 102,744,876 (GRCm38) |
Y119* |
probably null |
Het |
| Tmem43 |
C |
A |
6: 91,482,318 (GRCm38) |
P257Q |
probably benign |
Het |
| Tmprss13 |
A |
G |
9: 45,337,132 (GRCm38) |
|
probably null |
Het |
| Trove2 |
G |
T |
1: 143,760,075 (GRCm38) |
N444K |
probably benign |
Het |
| Ubr5 |
T |
C |
15: 37,972,980 (GRCm38) |
T2626A |
probably damaging |
Het |
| Vmn1r196 |
T |
A |
13: 22,293,836 (GRCm38) |
V215D |
probably damaging |
Het |
| Vmn1r22 |
G |
T |
6: 57,900,332 (GRCm38) |
T220K |
probably benign |
Het |
| Vmn2r116 |
G |
A |
17: 23,387,279 (GRCm38) |
M388I |
possibly damaging |
Het |
| Vmn2r74 |
A |
C |
7: 85,961,410 (GRCm38) |
C25G |
probably damaging |
Het |
| Xndc1 |
T |
C |
7: 102,080,616 (GRCm38) |
|
probably benign |
Het |
| Zfp282 |
A |
G |
6: 47,897,881 (GRCm38) |
D340G |
probably damaging |
Het |
| Zfp282 |
T |
A |
6: 47,905,053 (GRCm38) |
I558N |
possibly damaging |
Het |
| Zfp316 |
T |
A |
5: 143,264,491 (GRCm38) |
T56S |
unknown |
Het |
| Zfp345 |
A |
G |
2: 150,474,559 (GRCm38) |
|
probably benign |
Het |
|
| Other mutations in Cd109 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Cd109
|
APN |
9 |
78,616,969 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00465:Cd109
|
APN |
9 |
78,660,934 (GRCm38) |
nonsense |
probably null |
|
|
IGL00667:Cd109
|
APN |
9 |
78,684,877 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01432:Cd109
|
APN |
9 |
78,698,123 (GRCm38) |
missense |
probably benign |
|
|
IGL01795:Cd109
|
APN |
9 |
78,661,765 (GRCm38) |
splice site |
probably benign |
|
|
IGL02343:Cd109
|
APN |
9 |
78,688,955 (GRCm38) |
splice site |
probably benign |
|
|
IGL02450:Cd109
|
APN |
9 |
78,695,850 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
IGL02699:Cd109
|
APN |
9 |
78,671,989 (GRCm38) |
splice site |
probably benign |
|
|
IGL02738:Cd109
|
APN |
9 |
78,691,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02797:Cd109
|
APN |
9 |
78,661,713 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL03160:Cd109
|
APN |
9 |
78,661,056 (GRCm38) |
splice site |
probably null |
|
|
IGL03349:Cd109
|
APN |
9 |
78,636,485 (GRCm38) |
missense |
probably benign |
0.34 |
|
FR4589:Cd109
|
UTSW |
9 |
78,712,529 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R0048:Cd109
|
UTSW |
9 |
78,680,021 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R0060:Cd109
|
UTSW |
9 |
78,703,107 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0060:Cd109
|
UTSW |
9 |
78,703,107 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0158:Cd109
|
UTSW |
9 |
78,688,932 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R0659:Cd109
|
UTSW |
9 |
78,680,170 (GRCm38) |
splice site |
probably benign |
|
|
R0709:Cd109
|
UTSW |
9 |
78,671,978 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0840:Cd109
|
UTSW |
9 |
78,664,330 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0909:Cd109
|
UTSW |
9 |
78,636,473 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0945:Cd109
|
UTSW |
9 |
78,688,941 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R1344:Cd109
|
UTSW |
9 |
78,672,550 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R1471:Cd109
|
UTSW |
9 |
78,654,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1484:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R1570:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R1688:Cd109
|
UTSW |
9 |
78,705,091 (GRCm38) |
missense |
probably benign |
0.17 |
|
R1773:Cd109
|
UTSW |
9 |
78,703,724 (GRCm38) |
missense |
probably benign |
0.21 |
|
R1813:Cd109
|
UTSW |
9 |
78,617,005 (GRCm38) |
missense |
probably benign |
0.04 |
|
R2004:Cd109
|
UTSW |
9 |
78,703,762 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2083:Cd109
|
UTSW |
9 |
78,667,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2483:Cd109
|
UTSW |
9 |
78,667,357 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2857:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2858:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2859:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2911:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2912:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2914:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2927:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3623:Cd109
|
UTSW |
9 |
78,667,357 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3713:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3760:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3762:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3771:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3772:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3773:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3916:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3917:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4117:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4260:Cd109
|
UTSW |
9 |
78,636,463 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R4387:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4389:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4526:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4527:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4528:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4700:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4708:Cd109
|
UTSW |
9 |
78,672,589 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4723:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4750:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4751:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4754:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4755:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4773:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4984:Cd109
|
UTSW |
9 |
78,634,677 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5259:Cd109
|
UTSW |
9 |
78,710,152 (GRCm38) |
missense |
probably benign |
0.30 |
|
R5353:Cd109
|
UTSW |
9 |
78,710,239 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5440:Cd109
|
UTSW |
9 |
78,680,164 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5559:Cd109
|
UTSW |
9 |
78,660,968 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5701:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R5995:Cd109
|
UTSW |
9 |
78,700,279 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5997:Cd109
|
UTSW |
9 |
78,705,062 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6103:Cd109
|
UTSW |
9 |
78,698,314 (GRCm38) |
splice site |
probably null |
|
|
R6174:Cd109
|
UTSW |
9 |
78,665,546 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6410:Cd109
|
UTSW |
9 |
78,657,516 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6529:Cd109
|
UTSW |
9 |
78,712,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6655:Cd109
|
UTSW |
9 |
78,684,938 (GRCm38) |
missense |
probably benign |
0.44 |
|
R6704:Cd109
|
UTSW |
9 |
78,680,075 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6772:Cd109
|
UTSW |
9 |
78,680,810 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R6817:Cd109
|
UTSW |
9 |
78,714,955 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6903:Cd109
|
UTSW |
9 |
78,636,603 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7294:Cd109
|
UTSW |
9 |
78,712,635 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7432:Cd109
|
UTSW |
9 |
78,714,943 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7566:Cd109
|
UTSW |
9 |
78,680,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7767:Cd109
|
UTSW |
9 |
78,710,159 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7986:Cd109
|
UTSW |
9 |
78,688,766 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8017:Cd109
|
UTSW |
9 |
78,707,546 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R8019:Cd109
|
UTSW |
9 |
78,707,546 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R8050:Cd109
|
UTSW |
9 |
78,664,351 (GRCm38) |
missense |
probably benign |
0.28 |
|
R8225:Cd109
|
UTSW |
9 |
78,661,690 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8269:Cd109
|
UTSW |
9 |
78,665,682 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8479:Cd109
|
UTSW |
9 |
78,667,346 (GRCm38) |
nonsense |
probably null |
|
|
R8493:Cd109
|
UTSW |
9 |
78,657,519 (GRCm38) |
missense |
probably benign |
0.41 |
|
R8781:Cd109
|
UTSW |
9 |
78,636,647 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8977:Cd109
|
UTSW |
9 |
78,707,528 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9051:Cd109
|
UTSW |
9 |
78,712,531 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R9051:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R9228:Cd109
|
UTSW |
9 |
78,669,760 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R9366:Cd109
|
UTSW |
9 |
78,714,993 (GRCm38) |
missense |
probably benign |
0.11 |
|
R9430:Cd109
|
UTSW |
9 |
78,667,416 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9572:Cd109
|
UTSW |
9 |
78,660,306 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9691:Cd109
|
UTSW |
9 |
78,703,792 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9736:Cd109
|
UTSW |
9 |
78,712,636 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9749:Cd109
|
UTSW |
9 |
78,684,884 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9751:Cd109
|
UTSW |
9 |
78,698,160 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9752:Cd109
|
UTSW |
9 |
78,707,552 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9789:Cd109
|
UTSW |
9 |
78,634,662 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R9797:Cd109
|
UTSW |
9 |
78,671,935 (GRCm38) |
missense |
probably benign |
0.04 |
|
RF002:Cd109
|
UTSW |
9 |
78,712,528 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF002:Cd109
|
UTSW |
9 |
78,712,523 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF003:Cd109
|
UTSW |
9 |
78,712,531 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF011:Cd109
|
UTSW |
9 |
78,712,528 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF013:Cd109
|
UTSW |
9 |
78,712,531 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF047:Cd109
|
UTSW |
9 |
78,712,527 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF060:Cd109
|
UTSW |
9 |
78,712,525 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
Z1177:Cd109
|
UTSW |
9 |
78,691,313 (GRCm38) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCATCCCTTTAGTAGACGGGGAC -3'
(R):5'- TCTTCATTTACAGACAGCCTGCCAC -3'
Sequencing Primer
(F):5'- attacctgacattcagaaattctcc -3'
(R):5'- AGCCTGCCACCTGCATC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation